{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T10:17:43Z","timestamp":1695896263186},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2009,5,13]],"date-time":"2009-05-13T00:00:00Z","timestamp":1242172800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Metab Brain Dis"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1007\/s11011-009-9141-x","type":"journal-article","created":{"date-parts":[[2009,5,12]],"date-time":"2009-05-12T03:56:43Z","timestamp":1242100603000},"page":"723-731","source":"Crossref","is-referenced-by-count":3,"title":["Cysteamine prevents inhibition of adenylate kinase caused by cystine in rat brain cortex"],"prefix":"10.1007","volume":"24","author":[{"given":"Vandr\u00e9","family":"Casagrande Figueiredo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciane Rosa","family":"Feksa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clovis Milton Duval","family":"Wannmacher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,5,13]]},"reference":[{"key":"9141_CR1","first-page":"839","volume":"265","author":"A Ben-Nun","year":"1993","unstructured":"Ben-Nun A, Bashan N, Potashnik R, Cohen-Luria R, Moran A (1993) Cystine loading induces Fanconi\u2019s syndrome in rats: in vivo and vesicle studies. Am. J. Physiol. 265:839\u2013844","journal-title":"Am. J. Physiol."},{"key":"9141_CR2","doi-asserted-by":"crossref","first-page":"C516","DOI":"10.1152\/ajpcell.1992.263.2.C516","volume":"263","author":"A Ben-Nun","year":"1992","unstructured":"Ben-Nun A, Bashan N, Potashnik R, Cohen-luria R, Moran A (1992) Cystine dimethyl ester reduces the forces driving sodium-dependent transport in Llc-Pk1 cells. Am. J. Physiol. 263:C516\u2013C520","journal-title":"Am. J. Physiol."},{"key":"9141_CR3","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/s004410100424","volume":"306","author":"A Burlacu","year":"2001","unstructured":"Burlacu A, Jinga V, Gafencu AV, Simionescu M (2001) Severity of oxidative stress generates different mechanisms of endothelial cell death. Cell Tissue Res. 306:409\u2013416","journal-title":"Cell Tissue Res."},{"key":"9141_CR4","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1097\/01.ASN.0000023681.13865.25","volume":"13","author":"I \u00c7cetinkaya","year":"2002","unstructured":"\u00c7cetinkaya I, Schlatter E, Hirsch JR, Herter P, Harms E, Kleta R (2002) Inhibition of Na+-dependent transporters in cystine-loaded human renal cells: electrophysiological studies on the Fanconi syndrome of cystinosis. J. Am. Soc. Nephrol. 13:2085\u20132093","journal-title":"J. Am. Soc. Nephrol."},{"key":"9141_CR5","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1172\/JCI115103","volume":"87","author":"C Coor","year":"1991","unstructured":"Coor C, Salmon RF, Quigley R, Marver D, Baum M (1991) Role of adenosine- triphosphate (ATP) and Na+, K+ -ATPase in the inhibition of proximal tubule transport with intracellular cystine loading. J. Clin. Invest. 87:955\u2013961","journal-title":"J. Clin. Invest."},{"key":"9141_CR6","unstructured":"Das, U.N. (2006). Pyruvate is an endogenous anti-inflammatory and anti-oxidant molecule. Med. Sci. Monit. 12: RA79-84"},{"key":"9141_CR7","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.1242\/jeb.00426","volume":"206","author":"PP Dzeja","year":"2003","unstructured":"Dzeja PP, Terzic A (2003) Phosphotransfer networks and cellular energetics. J. Exp. Biol. 206:2039\u20132047","journal-title":"J. Exp. Biol."},{"key":"9141_CR8","doi-asserted-by":"crossref","first-page":"10156","DOI":"10.1073\/pnas.152259999","volume":"99","author":"PP Dzeja","year":"2002","unstructured":"Dzeja PP, Bortolon R, Perez-Terzic C, Holmuhamedov EL, Terzic A (2002) Energetic communication between mitochondria and nucleus directed by catalyzed phosphotransfer. Proc. Natl. Acad. Sci. USA 99:10156\u201310161","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"9141_CR9","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1161\/01.RES.84.10.1137","volume":"84","author":"PP Dzeja","year":"1999","unstructured":"Dzeja PP, Vitkevicius KT, Redfield MM, Burnettm JC, Terzic A (1999) Adenylate Kinase\u2013Catalyzed Phosphotransfer in the Myocardium: Increased Contribution in Heart Failure. Circ. Res. 84:1137\u20131143","journal-title":"Circ. Res."},{"key":"9141_CR10","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.brainres.2004.03.035","volume":"1012","author":"LR Feksa","year":"2004","unstructured":"Feksa LR, Cornelio A, Dutra-Filho CS, Wyse ATS, Wajner M, Wannmacher CMD (2004) Inhibition of pyruvate kinase activity by cystine in brain cortex of rats. Brain. Res. 1012:93\u2013100","journal-title":"Brain. Res."},{"key":"9141_CR11","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.neuint.2004.11.008","volume":"46","author":"RMM Fleck","year":"2005","unstructured":"Fleck RMM, Rodrigues-Junior V, Giacomazzi J, Parissoto D, Dutra-Filho CS, Wyse ATS, Wajner M, Wannmacher CMD (2005) Cysteamine prevents and reverses the inhibition of creatine kinase activity caused by cystine in rat brain cortex. Neurochem. Int. 46:391\u2013397","journal-title":"Neurochem. Int."},{"key":"9141_CR12","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1681\/ASN.V62269","volume":"6","author":"JW Foreman","year":"1995","unstructured":"Foreman JW, Benson LL, Wellons M, Avner ED, Sweeney W, Nissim I, Nissim I (1995) Metabolic studies of rat renal tubule cells loaded with cystine: the cystine dimethylester model of cystinosis. J. Am. Soc. Nephrol. 6:269\u2013272","journal-title":"J. Am. Soc. Nephrol."},{"key":"9141_CR13","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/0026-0495(87)90246-0","volume":"36","author":"JW Foreman","year":"1987","unstructured":"Foreman JW, Bowring MA, Lee J, States B, Segal S (1987) Effect of cystine dimethyl ester on renal solute handling and isolated renal tubule transport in the rat: A new model Fanconi syndrome. Metab. 36:1185\u20131191","journal-title":"Metab."},{"issue":"1","key":"9141_CR14","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/s00431-003-1349-x","volume":"162","author":"WA Gahl","year":"2003","unstructured":"Gahl WA (2003) Early oral cysteamine therapy for nephropathic cystinosis. Eur. J. Pediatr. 162(1):38\u201341","journal-title":"Eur. J. Pediatr."},{"key":"9141_CR15","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1056\/NEJMra020552","volume":"347","author":"WA Gahl","year":"2002","unstructured":"Gahl WA, Thoene JG, Schneider JA (2002) Cystinosis. N. Engl. J. Med. 347:111\u2013121","journal-title":"N. Engl. J. Med."},{"key":"9141_CR16","first-page":"5085","volume-title":"The Metabolic & Molecular Bases of Inherited Diseases","author":"WA Gahl","year":"2001","unstructured":"Gahl WA, Thoene JG, Schneider JA (2001) Cystinosis: a disorder of lysosomal membrane transport. In: Scriver CR, Beaudet AL, Sly WS, Valle D (eds) The Metabolic & Molecular Bases of Inherited Diseases. McGraw- Hill, New York, pp 5085\u20135108"},{"key":"9141_CR17","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0891-5849(91)90002-K","volume":"10","author":"FB Gonzalez","year":"1991","unstructured":"Gonzalez FB, Llesuy S, Boveris A (1991) Hydroperoxide initiated chemiluminescence: an assay for oxidative stress in biopsies of heart, liver, and muscle. Free Radic. Biol. Med. 10:93\u2013100","journal-title":"Free Radic. Biol. Med."},{"key":"9141_CR18","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1007\/s11064-007-9486-7","volume":"33","author":"A Kessler","year":"2008","unstructured":"Kessler A, Biasibetti M, da Silva Melo DA, Wajner M, Dutra-Filho CS, Wyse ATS, Wannmacher CMD (2008) Antioxidant Effect of Cysteamine in Brain Cortex of Young Rats. Neurochem. Res. 33:737\u2013744","journal-title":"Neurochem. Res."},{"key":"9141_CR19","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1007\/s00467-006-0005-x","volume":"21","author":"GF Laube","year":"2006","unstructured":"Laube GF, Shah V, Stewart VC, Hargreaves IP, Haq MR, Heales SJ, van\u2019t Hoff WG (2006) Glutathione depletion and increased apoptosis rate in human cystinotic proximal tubular cells. Pediatr. Nephrol. 21:503\u2013509","journal-title":"Pediatr. Nephrol."},{"key":"9141_CR20","first-page":"46","volume-title":"SPSS for intermediate statistics","author":"NL Leech","year":"2005","unstructured":"Leech NL, Barrett KC, Morgan GA (2005) SPSS for intermediate statistics. Use and interpretation, Lawrence Erlbaum Associates Publishers, London, pp 46\u201362"},{"key":"9141_CR21","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1203\/01.pdr.0000196334.46940.54","volume":"59","author":"EN Levtchenko","year":"2006","unstructured":"Levtchenko EN, Wilmer MJG, Janssen AJM, Koenderink JB, Visch AJ, Willems PH, Graaf-Hess A, Blom HJ, van den Heuvel LP, Monnens LA (2006) Decreased ATP content and intact mitochondrial energy generating capacity in human cystinotic fibroblasts. Pediatr. Res. 59:287\u2013292","journal-title":"Pediatr. Res."},{"issue":"3","key":"9141_CR22","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1177\/030089168507100305","volume":"71","author":"SF Llesuy","year":"1985","unstructured":"Llesuy SF, Milei J, Molina H (1985) Comparison of lipid peroxidation and myocardial damage induced by adriamycin and 40-epiadriamycin in mice. Tumori. 71(3):241\u2013249","journal-title":"Tumori."},{"issue":"1","key":"9141_CR23","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1042\/bj2370271","volume":"237","author":"JB Lloyd","year":"1986","unstructured":"Lloyd JB (1986) Disulphide reduction in lysosomes. The role of cysteine. Biochem. J. 237(1):271\u2013272","journal-title":"Biochem. J."},{"key":"9141_CR24","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","author":"OH Lowry","year":"1951","unstructured":"Lowry OH, Rosebrough NJ, Farr AL (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:265\u2013275","journal-title":"J. Biol. Chem."},{"key":"9141_CR25","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.arcmed.2006.09.013","volume":"38","author":"PRP Oliveira","year":"2007","unstructured":"Oliveira PRP, Rodrigues-Junior V, Rech VC, Wannmacher CMD (2007) Cystine Inhibits Creatine Kinase Activity in Pig Retina. Arch. Med. Res. 38:164\u2013169","journal-title":"Arch. Med. Res."},{"issue":"1","key":"9141_CR26","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1042\/bj0610116","volume":"61","author":"IT Oliver","year":"1955","unstructured":"Oliver IT (1955) A Spectrophotometric Method for the Determination of Creatine Phosphokinase and Myokinase. Biochem. J. 61(1):116\u2013122","journal-title":"Biochem. J."},{"key":"9141_CR27","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/s00467-004-1712-9","volume":"20","author":"MA Park","year":"2005","unstructured":"Park MA, Thoene JG (2005) Potential role of apoptosis in development of the cystinotic phenotype. Pediatr. Nephrol. 20:441\u2013446","journal-title":"Pediatr. Nephrol."},{"key":"9141_CR28","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1074\/jbc.270.3.1179","volume":"270","author":"RL Pisoni","year":"1995","unstructured":"Pisoni RL, Park GY, Velilla VQ, Thoene JG (1995) Detection and characterization of a transport system mediating cysteamine entry into human fibroblast lysosomes. Specificity for aminoethylthiol and aminoethylsulfide derivatives. J. Biol. Chem. 270:1179\u20131184","journal-title":"J. Biol. Chem."},{"key":"9141_CR29","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/S0021-9258(19)41945-5","volume":"250","author":"NC Price","year":"1975","unstructured":"Price NC, Cohn M, Schirmer RH (1975) Fluorescent and Spin Label Probes of the Environments of the Sulfhydryl Groups of Porcine Muscle Adenylate Kinase. J. Biol. Chem. 250:644\u2013652","journal-title":"J. Biol. Chem."},{"key":"9141_CR30","doi-asserted-by":"crossref","first-page":"41424","DOI":"10.1074\/jbc.M007903200","volume":"275","author":"D Pucar","year":"2000","unstructured":"Pucar D, Janssen E, Dzeja PP, Juranic N, Macura S, Wieringa B, Terzic A (2000) Compromised Energetics in the Adenylate Kinase AK1 Gene Knockout Heart under Metabolic Stress. J. Biol. Chem. 275:41424\u201341429","journal-title":"J. Biol. Chem."},{"key":"9141_CR31","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1007\/s00467-007-0494-2","volume":"22","author":"VC Rech","year":"2007","unstructured":"Rech VC, Feksa LR, Amaral MFA, Koch GW, Wajner M, Dutra-Filho CS, Wyse ATS, Wannmacher CMD (2007) Promotion of oxidative stress in kidney of rats loaded with cystine dimethyl ester. Pediatr. Nephro. L 22:1121\u20131128","journal-title":"Pediatr. Nephro. L"},{"key":"9141_CR32","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.bbadis.2004.02.006","volume":"1689","author":"TG Rosa","year":"2004","unstructured":"Rosa TG, Wyse ATS, Wajner M, Wannmacher CMD (2004) Cysteamine prevents and reverses the inhibition of pyruvate kinase activity caused by cystine in rat heart. Biochim. Biophys. Acta 1689:114\u2013119","journal-title":"Biochim. Biophys. Acta"},{"key":"9141_CR33","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1172\/JCI114443","volume":"85","author":"RF Salmon","year":"1990","unstructured":"Salmon RF, Baum M (1990) Intracellular Cystine Loading Inhibits Transport in the Rabbit Proximal Convoluted Tubule. J. Clin. Invest. 85:340\u2013344","journal-title":"J. Clin. Invest."},{"key":"9141_CR34","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/ng0498-319","volume":"18","author":"M Town","year":"1998","unstructured":"Town M, Jean G, Cherqui S, Attard M, Forestier L, Whitmore S, Callen D, Gribouval O, Broyer M, Bates G, van\u2019t Hoff W, Antignac C (1998) A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis. Nat. Genet. 18:319\u2013324","journal-title":"Nat. Genet."},{"key":"9141_CR35","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1042\/bj1070311","volume":"107","author":"AG Weeds","year":"1968","unstructured":"Weeds AG, Noda L (1968) Amino Acid Sequences around the Thiol Groups of Myokinase. Biochem J. 107:311\u2013312","journal-title":"Biochem J."},{"key":"9141_CR36","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.abb.2005.10.003","volume":"444","author":"M Willemoes","year":"2005","unstructured":"Willemoes M, Kilstrup M (2005) Nucleoside triphosphate synthesis catalysed by Adenylate Kinase is ADP dependent. Arch. Biochem. Biophys. 444:195\u2013199","journal-title":"Arch. Biochem. Biophys."},{"key":"9141_CR37","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1203\/PDR.0b013e31809fd9a7","volume":"62","author":"MJ Wilmer","year":"2007","unstructured":"Wilmer MJ, Willems PH, Verkaart S, Visch HJ, de Graaf-Hess A, Blom HJ, Monnens LA, van den Heuvel LP, Levtchenko EN (2007) Cystine dimethylester model of cystinosis: still reliable? Pediatr. Res. 62:151\u20135","journal-title":"Pediatr. Res."},{"key":"9141_CR38","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.bbrc.2005.09.094","volume":"337","author":"MJ Wilmer","year":"2005","unstructured":"Wilmer MJ, de Graaf-Hess A, Blom HJ, Dijkman HB, Monnens LA, van den Heuvel LP, Levtchenko EM (2005) Elevated oxidized glutathione in cystinotic proximal tubular epithelial cells. Biochem. Biophys. Res. Commun. 337:610\u2013614","journal-title":"Biochem. Biophys. Res. Commun."}],"container-title":["Metabolic Brain Disease"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11011-009-9141-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11011-009-9141-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11011-009-9141-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,5]],"date-time":"2021-10-05T05:52:16Z","timestamp":1633413136000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11011-009-9141-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5,13]]},"references-count":38,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["9141"],"URL":"https:\/\/doi.org\/10.1007\/s11011-009-9141-x","relation":{},"ISSN":["0885-7490","1573-7365"],"issn-type":[{"value":"0885-7490","type":"print"},{"value":"1573-7365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5,13]]}}}