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SJ van Rensburg, C Hattingh, ME Kemp and KE Moremi were supported by Winetech, South Africa (Grant Number N07\/09\/203), and AVP by the Strategic Health Innovation Partnerships Unit of the South African Medical Research Council (MRC), with funds received from the Department of Science and Innovation, South Africa (Grant number S003665). The funding bodies had no role in the design of the study, collection, analysis, and interpretation of data or in writing of the manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Financial disclosure"}},{"value":"SJVR and MJK are listed as inventors on patent number 2010\/ 00058 filed by Stellenbosch University. MJK is also a director and shareholder of Gknowmix (Pty) Ltd., a spin out company of the South African Medical Research Council. The remaining authors declared no conflict of interest. No writing assistance was utilised in the preparation of this manuscript.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was approved by the Human Research Ethics Committee (HREC) of the University of Stellenbosch (N07\/09\/203).","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Both participants gave written informed consent for study participation.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Both participants gave written informed consent for the publication of the case reports.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}