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The experimental protocols were approved by Ethical Committee Area 2 Milan (ID:721) and performed in accordance with the institutional review board of the Fondazione IRCCS Ca\u2019 Granda Ospedale Maggiore Policlinico.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The patients provided written informed consent for all aspects of the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}