{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T22:39:17Z","timestamp":1776638357783,"version":"3.51.2"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T00:00:00Z","timestamp":1632441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T00:00:00Z","timestamp":1632441600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"RBFR","award":["\u2116 18-315-00228 mol_\u0430"],"award-info":[{"award-number":["\u2116 18-315-00228 mol_\u0430"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Metab Brain Dis"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1007\/s11011-021-00837-x","type":"journal-article","created":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T15:26:16Z","timestamp":1632497176000},"page":"2473-2482","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Stress load and neurodegeneration after gastrostomy tube placement in amyotrophic lateral sclerosis patients"],"prefix":"10.1007","volume":"36","author":[{"given":"L.","family":"Brylev","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Fominykh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Chernenkaia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Chernenkiy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Gorbachev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ataulina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Izvekov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Monakhov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Olenichev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Orlov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Turin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Loginov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Rautbart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Baymukanov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Parshikov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Demeshonok","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Yakovlev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Druzhkova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Guekht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Gulyaeva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,9,24]]},"reference":[{"key":"837_CR1","doi-asserted-by":"publisher","unstructured":"Abrahams S, Newton J, Niven E, Foley J, Bak T (2014) Screening for cognition and behaviour changes in ALS. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration15(1\u20132):9\u201314 https:\/\/doi.org\/10.3109\/21678421.2013.805784","DOI":"10.3109\/21678421.2013.805784"},{"issue":"2","key":"837_CR2","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1177\/1094428112470848","volume":"16","author":"H Aguinis","year":"2013","unstructured":"Aguinis H, Gottfredson R, Joo H (2013) Best-Practice Recommendations for Defining, Identifying, and Handling Outliers. Organ Res Methods 16(2):270\u2013301. https:\/\/doi.org\/10.1177\/1094428112470848","journal-title":"Organ Res Methods"},{"key":"837_CR3","doi-asserted-by":"publisher","unstructured":"Andersen PM et al (2012) EFNS Task Force on Diagnosis and Management of Amyotrophic Lateral Sclerosis: et al. EFNS guidelines on the clinical management of amyotrophic lateral sclerosis (MALS)\u2013revised report of an EFNS task force. European journal of neurology 19: 360\u2013375. https:\/\/doi.org\/10.1111\/j.1468-1331.2005.01351.x","DOI":"10.1111\/j.1468-1331.2005.01351.x"},{"issue":"4","key":"837_CR4","doi-asserted-by":"publisher","first-page":"272","DOI":"10.3109\/17482968.2011.577786","volume":"12","author":"N Atassi","year":"2011","unstructured":"Atassi N, Cudkowicz M, Schoenfeld D (2011) Advanced Statistical Methods to Study the Effects of Gastric Tube and Non-Invasive Ventilation on Functional Decline and Survival in Amyotrophic Lateral Sclerosis 12(4):272\u2013277. https:\/\/doi.org\/10.3109\/17482968.2011.577786","journal-title":"Advanced Statistical Methods to Study the Effects of Gastric Tube and Non-Invasive Ventilation on Functional Decline and Survival in Amyotrophic Lateral Sclerosis"},{"key":"837_CR5","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1186\/s12913-016-1492-5","volume":"16","author":"H Aust","year":"2016","unstructured":"Aust H, R\u00fcsch D, Schuster M, Sturm T, Brehm F, Nestoriuc Y (2016) Coping strategies in anxious surgical patients. BMC Health Serv Res 16:250. https:\/\/doi.org\/10.1186\/s12913-016-1492-5","journal-title":"BMC Health Serv Res"},{"key":"837_CR6","doi-asserted-by":"publisher","unstructured":"Ben-Eliyahu S (2020) Tumor Excision as a Metastatic Russian Roulette: Perioperative Interventions to Improve Long-Term Survival of Cancer Patients. Trends Cancer9:S2405\u20138033(20)30188\u20136. https:\/\/doi.org\/10.1016\/j.trecan.2020.06.004.","DOI":"10.1016\/j.trecan.2020.06.004"},{"issue":"1","key":"837_CR7","doi-asserted-by":"publisher","first-page":"17652","DOI":"10.1038\/s41598-017-17389-9","volume":"7","author":"H Blasco","year":"2017","unstructured":"Blasco H, Veyrat-Durebex C, Bocca C et al (2017) Lipidomics Reveals Cerebrospinal-Fluid Signatures of ALS. Sci Rep 7(1):17652. https:\/\/doi.org\/10.1038\/s41598-017-17389-9","journal-title":"Sci Rep"},{"issue":"9","key":"837_CR8","doi-asserted-by":"publisher","first-page":"223","DOI":"10.3390\/brainsci9090223","volume":"9","author":"L Bond","year":"2019","unstructured":"Bond L, Ganguly P, Khamankar N et al (2019) A Comprehensive Examination of Percutaneous Endoscopic Gastrostomy and Its Association with Amyotrophic Lateral Sclerosis Patient Outcomes. Brain Sci 9(9):223. https:\/\/doi.org\/10.3390\/brainsci9090223","journal-title":"Brain Sci"},{"key":"837_CR9","doi-asserted-by":"publisher","unstructured":"Brooks B, Miller R, Swash M, Munsat T and World Federation of Neurology Research Group on Motor Neuron Diseases (2000) El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis.\u00a0Amyotrophic lateral sclerosis and other motor neuron disorders 1(5): 293\u2013299.https:\/\/doi.org\/10.1080\/146608200300079536","DOI":"10.1080\/146608200300079536"},{"issue":"5","key":"837_CR10","doi-asserted-by":"publisher","first-page":"1115","DOI":"10.1007\/s10072-019-04201-x","volume":"41","author":"B Che\u0142stowska","year":"2020","unstructured":"Che\u0142stowska B, Ku\u017ama-Kozakiewicz M (2020) Biochemical parameters in determination of nutritional status in amyotrophic lateral sclerosis. Neurol Sci 41(5):1115\u20131124. https:\/\/doi.org\/10.1007\/s10072-019-04201-x","journal-title":"Neurol Sci"},{"key":"837_CR11","doi-asserted-by":"publisher","unstructured":"Chernenkaya V, Gorbachev K, Gorbachev D, Ataulina A, Fominykh V, Brylev L, Guekht A (2018) The Edinburgh Cognitive and Behavioral ALS Screen (ECAS): a Russian version. Zh Nevrol Psikhiatr Im S S Korsakova 118(12):36\u201339. https:\/\/doi.org\/10.17116\/jnevro201811812136","DOI":"10.17116\/jnevro201811812136"},{"key":"837_CR12","doi-asserted-by":"publisher","unstructured":"Chi\u00f2 A, Calvo A, Bovio G et al (2014) Piemonte and Valle d\u2019Aosta Register for Amyotrophic Lateral Sclerosis. Amyotrophic lateral sclerosis outcome measures and the role of albumin and creatinine: a population-based study. JAMA Neurol 71(9):1134\u201342. https:\/\/doi.org\/10.1001\/jamaneurol.2014.1129.","DOI":"10.1001\/jamaneurol.2014.1129"},{"key":"837_CR13","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/j.jns.2017.02.012","volume":"375","author":"S Choi","year":"2017","unstructured":"Choi S, Hong Y, Shin J et al (2017) Takotsubo cardiomyopathy in amyotrophic lateral sclerosis. J Neurol Sci 375:289\u2013293. https:\/\/doi.org\/10.1016\/j.jns.2017.02.012","journal-title":"J Neurol Sci"},{"issue":"15","key":"837_CR14","doi-asserted-by":"publisher","first-page":"e1370","DOI":"10.1212\/WNL.0000000000006317","volume":"91","author":"C Crockford","year":"2018","unstructured":"Crockford C, Newton J, Lonergan K et al (2018) ALS-specific cognitive and behavior changes associated with advancing disease stage in ALS. Neurology 91(15):e1370\u2013e1380. https:\/\/doi.org\/10.1212\/WNL.0000000000006317","journal-title":"Neurology"},{"issue":"2","key":"837_CR15","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1016\/j.ijcard.2014.08.101","volume":"177","author":"J Finsterer","year":"2014","unstructured":"Finsterer J, Wahbi K (2014) CNS disease triggering Takotsubo stress cardiomyopathy. Int J Cardiol 177(2):322\u2013329. https:\/\/doi.org\/10.1016\/j.ijcard.2014.08.101","journal-title":"Int J Cardiol"},{"issue":"3","key":"837_CR16","doi-asserted-by":"publisher","first-page":"327","DOI":"10.3988\/jcn.2018.14.3.327","volume":"14","author":"V Fominykh","year":"2018","unstructured":"Fominykh V, Vorobyeva A, Onufriev MV, Brylev L, Zakharova MN, Gulyaeva NV (2018) Interleukin-6, S-Nitrosothiols, and Neurodegeneration in Different CentralNervous System Demyelinating Disorders: Is There a Relationship? J Clin Neurol 14(3):327\u2013332. https:\/\/doi.org\/10.3988\/jcn.2018.14.3.327","journal-title":"J Clin Neurol"},{"issue":"11","key":"837_CR17","doi-asserted-by":"publisher","first-page":"1306","DOI":"10.1134\/S0006297919110087","volume":"84","author":"N Gulyaeva","year":"2019","unstructured":"Gulyaeva N (2019) Biochemical Mechanisms and Translational Relevance of Hippocampal Vulnerability to Distant Focal Brain Injury: The Price of Stress Response. Biochemistry (mosc) 84(11):1306\u20131328. https:\/\/doi.org\/10.1134\/S0006297919110087","journal-title":"Biochemistry (mosc)"},{"issue":"2","key":"837_CR18","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1080\/14660820410020349","volume":"5","author":"C Heffernan","year":"2004","unstructured":"Heffernan C et al (2004) Nutritional management in MND\/ALS patients: an evidence based review. Amyotroph Lateral Scler Other Motor Neuron Disord 5(2):72\u201383. https:\/\/doi.org\/10.1080\/14660820410020349","journal-title":"Amyotroph Lateral Scler Other Motor Neuron Disord"},{"issue":"9","key":"837_CR19","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1038\/sj.bdj.4801220","volume":"191","author":"CM Hill","year":"2001","unstructured":"Hill CM, Walker RV (2001) Salivary cortisol determinations and self-rating scales in the assessment of stress in patients undergoing the extraction of wisdom teeth. Br Dent J 191(9):513\u2013515. https:\/\/doi.org\/10.1038\/sj.bdj.4801220","journal-title":"Br Dent J"},{"issue":"1\u20132","key":"837_CR20","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1080\/21678421.2019.1674874","volume":"21","author":"F Hodgins","year":"2020","unstructured":"Hodgins F, Mulhern S, Abrahams S (2020) The clinical impact of the Edinburgh Cognitive and Behavioural ALS Screen (ECAS) and neuropsychological intervention in routine ALS care. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 21(1\u20132):92\u201399. https:\/\/doi.org\/10.1080\/21678421.2019.1674874","journal-title":"Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration"},{"issue":"2","key":"837_CR21","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1007\/s00540-019-02611-x","volume":"33","author":"A Hoeper","year":"2019","unstructured":"Hoeper A, Barbara D, Watson J et al (2019) Amyotrophic lateral sclerosis and anesthesia: a case series and review of the literature. J Anesth 33(2):257\u2013265. https:\/\/doi.org\/10.1007\/s00540-019-02611-x","journal-title":"J Anesth"},{"key":"837_CR22","doi-asserted-by":"publisher","unstructured":"Kalava A, Clendenen S, McKinney J, Bojaxhi E, Greengrass R (2016) Bilateral thoracic paravertebral nerve blocks for placement of percutaneous radiologic gastrostomy in patients with amyotrophic lateral sclerosis: a case series.\u00a0Romanian journal of anaesthesia and intensive care\u00a023(2):149\u2013153. https:\/\/doi.org\/10.21454\/rjaic.7518\/232.scl","DOI":"10.21454\/rjaic.7518\/232.scl"},{"issue":"1","key":"837_CR23","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.expneurol.2011.04.020","volume":"233","author":"M Larauche","year":"2012","unstructured":"Larauche M, Mulak A, Tach\u00e9 Y (2012) Stress and visceral pain: from animal models to clinical therapies. Exp Neurol 233(1):49\u201367. https:\/\/doi.org\/10.1016\/j.expneurol.2011.04.020","journal-title":"Exp Neurol"},{"issue":"5","key":"837_CR24","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1136\/jnnp-2014-307672","volume":"86","author":"C Lu","year":"2015","unstructured":"Lu C, Petzold A, Topping J et al (2015) Plasma neurofilament heavy chain levels and disease progression in amyotrophic lateral sclerosis: insights from a longitudinal study. J Neurol Neurosurg Psychiatry 86(5):565\u2013573. https:\/\/doi.org\/10.1136\/jnnp-2014-307672","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"5","key":"837_CR25","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1016\/j.bja.2019.08.011","volume":"123","author":"V Manou-Stathopoulou","year":"2019","unstructured":"Manou-Stathopoulou V, Korbonits M, Ackland GL (2019) Redefining the perioperative stress response: a narrative review. Br J Anaesth 123(5):570\u2013583. https:\/\/doi.org\/10.1016\/j.bja.2019.08.011","journal-title":"Br J Anaesth"},{"issue":"6","key":"837_CR26","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1007\/s00540-013-1644-2","volume":"27","author":"A Prabhakar","year":"2013","unstructured":"Prabhakar A, Owen CP, Kaye AD (2013) Anesthetic management of the patient with amyotrophic lateral sclerosis. J Anesth 27(6):909\u2013918. https:\/\/doi.org\/10.1007\/s00540-013-1644-2","journal-title":"J Anesth"},{"issue":"7","key":"837_CR27","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1016\/S1474-4422(15)00104-0","volume":"14","author":"ProGas Study Group","year":"2015","unstructured":"ProGas Study Group (2015) Gastrostomy in patients with amyotrophic lateral sclerosis (ProGas): a prospective cohort study. The Lancet Neurology 14(7):702\u2013709. https:\/\/doi.org\/10.1016\/S1474-4422(15)00104-0","journal-title":"The Lancet Neurology"},{"key":"837_CR28","doi-asserted-by":"publisher","unstructured":"Steinthorsdottir K, Kehlet H, Aasvang E (2017) Surgical stress response and the potential role of preoperative glucocorticoids on post-anesthesia care unit recovery.\u00a0Minerva anestesiologica 83(12):1324\u20131331. https:\/\/doi.org\/10.23736\/S0375-9393.17.11878-X","DOI":"10.23736\/S0375-9393.17.11878-X"},{"issue":"11","key":"837_CR29","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1097\/MEG.0000000000000959","volume":"29","author":"D Strijbos","year":"2017","unstructured":"Strijbos D, Hofstede J, Keszthelyi D, Masclee A, Gilissen L (2017) Percutaneous endoscopic gastrostomy under conscious sedation in patients with amyotrophic lateral sclerosis is safe: an observational study. Eur J Gastroenterol Hepatol 29(11):1303\u20131308. https:\/\/doi.org\/10.1097\/MEG.0000000000000959","journal-title":"Eur J Gastroenterol Hepatol"},{"issue":"8","key":"837_CR30","doi-asserted-by":"publisher","first-page":"615","DOI":"10.3109\/00365513.2013.835862","volume":"73","author":"R Toone","year":"2013","unstructured":"Toone R, Peacock O, Smith A, Thompson D, Drawer S, Cook C, Stokes KA (2013) Measurement of steroid hormones in saliva: Effects of sample storage condition. Scand J Clin Lab Invest 73(8):615\u2013621. https:\/\/doi.org\/10.3109\/00365513.2013.835862","journal-title":"Scand J Clin Lab Invest"},{"issue":"10","key":"837_CR31","doi-asserted-by":"publisher","first-page":"3112","DOI":"10.1016\/j.clnu.2020.01.018","volume":"39","author":"M Vergonjeanne","year":"2020","unstructured":"Vergonjeanne M, Fayemendy P, Marin B et al (2020) Predictive factors for gastrostomy at time of diagnosis and impact on survival in patients with amyotrophic lateral sclerosis. Clin Nutr 39(10):3112\u20133118. https:\/\/doi.org\/10.1016\/j.clnu.2020.01.018","journal-title":"Clin Nutr"}],"container-title":["Metabolic Brain Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11011-021-00837-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11011-021-00837-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11011-021-00837-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,10]],"date-time":"2021-11-10T06:10:05Z","timestamp":1636524605000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11011-021-00837-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,24]]},"references-count":31,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["837"],"URL":"https:\/\/doi.org\/10.1007\/s11011-021-00837-x","relation":{},"ISSN":["0885-7490","1573-7365"],"issn-type":[{"value":"0885-7490","type":"print"},{"value":"1573-7365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,24]]},"assertion":[{"value":"13 December 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 September 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 September 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no conflicts of interest to declare that are relevant to the content of this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest\/Competing interests"}},{"value":"This study was approved by the local Ethical Committee of Bujanov Moscow City Clinical Hospital. This study was performed in line with the principles of the Declaration of Helsinki.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.All patients signed informed concern for data publication.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate, consent for publication"}}]}}