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For full disclosure, relationships unrelated to this work are listed. Dr. Naga Chalasani served as a paid consultant to Abbvie, Madrigal, Zydus, Galectin, Boehringer-Ingelheim, Lilly, and Altimmune. He has research funding from NIH, Galectin, DSM, and Exact Sciences.\u00a0Dr. Chalasani has equity in RestUp, Inc, a start-up specializing in health care staff placement. Dr. Boustani receives consulting fees and honoria from Lilly, Eisa, BioGen, Genetech, ACADIA, Merck. Additionally, he has patents pending for the \u201cABC Took Kit\u201d and Agile Processes and has stock options in PPHM, RestUP and BlueAgillis.Ethics approval: This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Indiana University Institutional Review Board. (Last Date of Approval July 20, 2022\/No 1402496491).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors affirm that human research participants provided informed consent for publication of their data.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}}]}}