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All the experiments were conducted according to the standards recommended by the United States National Institute of Health Guide for the Care and Use of Laboratory Animals, and were approved by the Institutional Animal Care and Use Committee at Shanghai Pudong Hospital, Fudan University Pudong Medical Center (No.2020QKW-03).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"All the authors agreed to publish the article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication\u00a0"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors declare that they have no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"66"}}