{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T04:16:42Z","timestamp":1743394602926,"version":"3.40.3"},"reference-count":76,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T00:00:00Z","timestamp":1741996800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T00:00:00Z","timestamp":1741996800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Kerman University of Medical Sciences, Kerman, Iran","award":["99000705"],"award-info":[{"award-number":["99000705"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Metab Brain Dis"],"DOI":"10.1007\/s11011-025-01575-0","type":"journal-article","created":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T08:01:33Z","timestamp":1742025693000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Protective effects of omega-3 against procarbazine-induced brain damage in the cerebellum and CA1 Hippocampus of male rats: a focus on oxidative stress mechanisms"],"prefix":"10.1007","volume":"40","author":[{"given":"Maryam","family":"Abolghasemi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6215-8693","authenticated-orcid":false,"given":"Ali","family":"Shamsara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masoumeh","family":"Nozari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rana","family":"Eftekhar-vaghefi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masoumeh","family":"Baghalishahi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali Sarhadi","family":"Roodbari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5122-9900","authenticated-orcid":false,"given":"Mohammad Reza","family":"Afarinesh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,3,15]]},"reference":[{"key":"1575_CR1","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1146\/annurev-clinpsy-050817-084903","volume":"14","author":"TA Ahles","year":"2018","unstructured":"Ahles TA, Root JC (2018) Cognitive effects of cancer and cancer treatments. Ann Rev Clin Psychol 14:425\u2013451","journal-title":"Ann Rev Clin Psychol"},{"key":"1575_CR2","doi-asserted-by":"publisher","first-page":"e2993","DOI":"10.1002\/brb3.2993","volume":"13","author":"BBM Ahmadi","year":"2023","unstructured":"Ahmadi BBM, Afarinesh MR, Jafaripour L, Sheibani V (2023) Alteration in social interaction and tactile discrimination of juvenile autistic-like rats following tactile stimulation and whisker deprivation. Brain Behav 13:e2993","journal-title":"Brain Behav"},{"key":"1575_CR3","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1007\/s12031-014-0232-8","volume":"53","author":"HA Ali","year":"2014","unstructured":"Ali HA, Afifi M, Abdelazim AM, Mosleh YY (2014) Quercetin and Omega 3 ameliorate oxidative stress induced by aluminium chloride in the brain. J Mol Neurosci 53:654\u2013660","journal-title":"J Mol Neurosci"},{"key":"1575_CR4","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/j.jmau.2017.05.006","volume":"5","author":"G Altun","year":"2017","unstructured":"Altun G, Kaplan S, Deniz OG, Kocacan SE, Canan S, Davis D, Marangoz C (2017) Protective effects of melatonin and omega-3 on the hippocampus and the cerebellum of adult Wistar albino rats exposed to electromagnetic fields. J Microscopy Ultrastructure 5:230\u2013241","journal-title":"J Microscopy Ultrastructure"},{"key":"1575_CR5","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1002\/jnr.1210","volume":"66","author":"C Ananth","year":"2001","unstructured":"Ananth C, Thameem Dheen S, Gopalakrishnakone P, Kaur C (2001) Domoic acid-induced neuronal damage in the rat hippocampus: changes in apoptosis related genes (bcl\u20102, Bax, caspase\u20103) and microglial response. J Neurosci Res 66:177\u2013190","journal-title":"J Neurosci Res"},{"key":"1575_CR6","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/s12640-011-9265-8","volume":"21","author":"MC Antonelli","year":"2012","unstructured":"Antonelli MC, Guillemin GJ, Raisman-Vozari R, Del-Bel EA, Aschner M, Collins MA, Tizabi Y, Moratalla R, West AK (2012) New strategies in neuroprotection and neurorepair. Neurotox Res 21:49\u201356","journal-title":"Neurotox Res"},{"key":"1575_CR7","doi-asserted-by":"publisher","first-page":"213","DOI":"10.2147\/tcrm.2007.3.2.213","volume":"3","author":"J-P Armand","year":"2007","unstructured":"Armand J-P, Ribrag V, Harrousseau J-L, Abrey L (2007) Reappraisal of the use of procarbazine in the treatment of lymphomas and brain tumors. Ther Clin Risk Manag 3:213","journal-title":"Ther Clin Risk Manag"},{"key":"1575_CR8","doi-asserted-by":"crossref","unstructured":"Asadikaram G, Pourghdamyari H, Abolhassani M, Abbasi-Jorjandi M, Faramarz S, Yousefi F, Salimi F, Afshar RM, Asadikaram P, Shafiepour M (2022) Oxidative stress induction by pesticides may cause lung cancer incidence","DOI":"10.21203\/rs.3.rs-1204945\/v1"},{"key":"1575_CR9","doi-asserted-by":"publisher","first-page":"3893","DOI":"10.1038\/s41598-021-83024-3","volume":"11","author":"YV Bobkov","year":"2021","unstructured":"Bobkov YV, Walker Iii WB, Cattaneo AM (2021) Altered functional properties of the codling moth Orco mutagenized in the intracellular loop-3. Sci Rep 11:3893","journal-title":"Sci Rep"},{"key":"1575_CR10","first-page":"681","volume":"38","author":"JC Bradberry","year":"2013","unstructured":"Bradberry JC, Hilleman DE (2013) Overview of omega-3 fatty acid therapies. Pharm Ther 38:681","journal-title":"Pharm Ther"},{"key":"1575_CR11","doi-asserted-by":"crossref","unstructured":"Buege JA, Aust SD (1978) [30] Microsomal lipid peroxidation. Methods in Enzymology 52: 302\u2013310","DOI":"10.1016\/S0076-6879(78)52032-6"},{"key":"1575_CR12","doi-asserted-by":"crossref","unstructured":"Chalon S (2006) Omega-3 fatty acids and monoamine neurotransmission.75: 259\u2009\u2013\u200969","DOI":"10.1016\/j.plefa.2006.07.005"},{"key":"1575_CR13","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.bbr.2014.08.002","volume":"285","author":"SJ Cohen","year":"2015","unstructured":"Cohen SJ, Stackman RW Jr (2015) Assessing rodent hippocampal involvement in the novel object recognition task. A review. Behav Brain Res 285:105\u2013117","journal-title":"Behav Brain Res"},{"key":"1575_CR14","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.ejphar.2009.02.037","volume":"607","author":"BC Detanico","year":"2009","unstructured":"Detanico BC, Piato \u00c2L, Freitas JJ, Lhullier FL, Hidalgo MP, Caumo W, Elisabetsky E (2009) Antidepressant-like effects of melatonin in the mouse chronic mild stress model. Eur J Pharmacol 607:121\u2013125","journal-title":"Eur J Pharmacol"},{"key":"1575_CR15","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.mpsur.2017.12.002","volume":"36","author":"E Dickens","year":"2018","unstructured":"Dickens E, Ahmed S (2018) Principles of cancer treatment by chemotherapy. Surg (Oxford) 36:134\u2013138","journal-title":"Surg (Oxford)"},{"key":"1575_CR16","doi-asserted-by":"publisher","first-page":"44","DOI":"10.15835\/nbha4118929","volume":"41","author":"HS El-Beltagi","year":"2013","unstructured":"El-Beltagi HS, Mohamed HI (2013) Reactive oxygen species, lipid peroxidation and antioxidative defense mechanism. Notulae Botanicae Horti Agrobotanici Cluj-Napoca 41:44\u201357","journal-title":"Notulae Botanicae Horti Agrobotanici Cluj-Napoca"},{"key":"1575_CR17","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1592\/phco.30.5.540","volume":"30","author":"MJ Fesler","year":"2010","unstructured":"Fesler MJ, Becker-Koepke S, Di Bisceglie AM, Petruska PJ (2010) Procarbazine\u2010Induced hepatotoxicity: case report and review of the literature. Pharmacotherapy: J Hum Pharmacol Drug Therapy 30:540\u2013540","journal-title":"Pharmacotherapy: J Hum Pharmacol Drug Therapy"},{"key":"1575_CR18","doi-asserted-by":"publisher","first-page":"945","DOI":"10.3390\/nu11050945","volume":"11","author":"RD Freitas","year":"2019","unstructured":"Freitas RD, Campos MM (2019) Protective effects of omega-3 fatty acids in cancer-related complications. Nutrients 11:945","journal-title":"Nutrients"},{"key":"1575_CR19","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1016\/j.jpsychores.2008.03.005","volume":"65","author":"JA Greer","year":"2008","unstructured":"Greer JA, Pirl WF, Park ER, Lynch TJ, Temel JS (2008) Behavioral and psychological predictors of chemotherapy adherence in patients with advanced non-small cell lung cancer. J Psychosom Res 65:549\u2013552","journal-title":"J Psychosom Res"},{"key":"1575_CR20","doi-asserted-by":"publisher","first-page":"399","DOI":"10.3389\/fncel.2014.00399","volume":"8","author":"T Grundy","year":"2014","unstructured":"Grundy T, Toben C, Jaehne EJ, Corrigan F, Baune BT (2014) Long-term omega-3 supplementation modulates behavior, hippocampal fatty acid concentration, neuronal progenitor proliferation and central TNF-\u03b1 expression in 7 month old unchallenged mice. Front Cell Neurosci 8:399","journal-title":"Front Cell Neurosci"},{"key":"1575_CR21","doi-asserted-by":"crossref","unstructured":"Hanie MH, Reza AM, Mansoureh S, Fatemeh SB, Ali S (2024) Exploring the impact of melatonin and omega-3, individually and in combination, on cognitive function, histological changes, and oxidant-antioxidant balance in male rats with dorsal CA1 hippocampal lesions. Brain Res\u00a01840:149046","DOI":"10.1016\/j.brainres.2024.149046"},{"key":"1575_CR22","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1007\/s11745-010-3523-z","volume":"46","author":"A Harauma","year":"2011","unstructured":"Harauma A, Moriguchi T (2011) Dietary n-3 fatty acid deficiency in mice enhances anxiety induced by chronic mild stress. Lipids 46:409\u2013416","journal-title":"Lipids"},{"key":"1575_CR23","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1007\/s11064-008-9808-4","volume":"34","author":"E Head","year":"2009","unstructured":"Head E (2009) Oxidative damage and cognitive dysfunction: antioxidant treatments to promote healthy brain aging. Neurochem Res 34:670\u2013678","journal-title":"Neurochem Res"},{"key":"1575_CR24","doi-asserted-by":"publisher","first-page":"e42142","DOI":"10.1371\/journal.pone.0042142","volume":"7","author":"M Hennebelle","year":"2012","unstructured":"Hennebelle M, Balasse L, Latour A, Champeil-Potokar G, Denis S, Lavialle M, Gisquet-Verrier P, Denis I, Vancassel S (2012) Influence of omega-3 fatty acid status on the way rats adapt to chronic restraint stress. PLoS ONE 7:e42142","journal-title":"PLoS ONE"},{"key":"1575_CR25","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/0006-291X(76)90524-6","volume":"69","author":"J Hoebeke","year":"1976","unstructured":"Hoebeke J, Van Nijen G, De Brabander M (1976) Interaction of oncodazole (R 17934), a new anti-tumoral drug, with rat brain tubulin. Biochem Biophys Res Commun 69:319\u2013324","journal-title":"Biochem Biophys Res Commun"},{"key":"1575_CR26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/tera.1420300102","volume":"30","author":"J Johnson","year":"1984","unstructured":"Johnson J, Thompson D, Burek J, Haggerty G, Dyke I, Lower C, Solomon J (1984) The neuroteratogenicity of procarbazine in the rat: behavioral, morphological, and neurochemical aspects. Teratology 30:1\u201310","journal-title":"Teratology"},{"key":"1575_CR27","doi-asserted-by":"crossref","unstructured":"Kalu C, Woelke S, Zhang J, Belury M, Shen R, Clinton SK, Yee L (2019) Omega-3 fatty acids and ERPR (-) and HER2\/neu (+\/-) breast cancer prevention. J Clin Oncol 37:15","DOI":"10.1200\/JCO.2019.37.15_suppl.TPS1589"},{"key":"1575_CR28","first-page":"335","volume":"27","author":"KM Khoram-Abadi","year":"2024","unstructured":"Khoram-Abadi KM, Haratizadeh S, Basiri M, Parvan M, Pourjafari F, Aghaei I, Amiresmaili S, Nozari M (2024) Autistic-like behaviors are attenuated by Agmatine consumption during pregnancy: assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus. Iran J Basic Med Sci 27:335","journal-title":"Iran J Basic Med Sci"},{"key":"1575_CR29","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1007\/s00277-013-1853-7","volume":"93","author":"YR Kim","year":"2014","unstructured":"Kim YR, Kim SH, Chang JH, Suh C-O, Kim S-J, Kim Y, Hwang DY, Jang JE, Hyun SY, Cheong J-W (2014) Early response to high-dose methotrexate, vincristine, and procarbazine chemotherapy-adapted strategy for primary CNS lymphoma: no consolidation therapy for patients achieving early complete response. Ann Hematol 93:211\u2013219","journal-title":"Ann Hematol"},{"key":"1575_CR30","doi-asserted-by":"publisher","first-page":"205","DOI":"10.33549\/physiolres.930742","volume":"55","author":"M Kiray","year":"2006","unstructured":"Kiray M, Bagriyanik H, Pekcetin C, Ergur B, Uysal N, Ozyurt D, Buldan Z (2006) Deprenyl and the relationship between its effects on Spatial memory, oxidant stress and hippocampal neurons in aged male rats. Physiol Res 55:205","journal-title":"Physiol Res"},{"key":"1575_CR31","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1002\/pon.3378","volume":"23","author":"SL Kraft","year":"2014","unstructured":"Kraft SL, Baker NM, Carpenter J, Bostwick JR (2014) Procarbazine and antidepressants: a retrospective review of the risk of serotonin toxicity. Psycho-oncology 23:108\u2013113","journal-title":"Psycho-oncology"},{"key":"1575_CR32","doi-asserted-by":"publisher","first-page":"1290","DOI":"10.1002\/pbc.21387","volume":"50","author":"S Kupeli","year":"2008","unstructured":"Kupeli S, Varan A, Buyukpamukcu M (2008) Cerebellar dysfunction caused by procarbazine and consumption of excessive amount of bananas. Pediatr Blood Cancer 50:1290","journal-title":"Pediatr Blood Cancer"},{"key":"1575_CR33","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.ebiom.2018.05.028","volume":"32","author":"C Luo","year":"2018","unstructured":"Luo C, Ren H, Yao X, Shi Z, Liang F, Kang JX, Wan J-b, Pei Z, Su K-P, Su H (2018) Enriched brain omega-3 polyunsaturated fatty acids confer neuroprotection against microinfarction. EBioMedicine 32:50\u201361","journal-title":"EBioMedicine"},{"key":"1575_CR34","first-page":"59","volume":"5","author":"M Madmoli","year":"2018","unstructured":"Madmoli M (2018) Evaluation of chemotherapy complications in patients with cancer: A systematic review. Int J Res Stud Sci Eng Technol 5:59\u201364","journal-title":"Int J Res Stud Sci Eng Technol"},{"key":"1575_CR35","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.blre.2014.09.012","volume":"29","author":"RS Magge","year":"2015","unstructured":"Magge RS, DeAngelis LM (2015) The double-edged sword: neurotoxicity of chemotherapy. Blood Rev 29:93\u2013100","journal-title":"Blood Rev"},{"key":"1575_CR36","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1159\/000065419","volume":"46","author":"I Mart\u00ednez","year":"2002","unstructured":"Mart\u00ednez I, Quirarte GL, D\u00edaz-Cintra S, Quiroz C, Prado-Alcal\u00e1 RA (2002) Effects of lesions of hippocampal fields CA1 and CA3 on acquisition of inhibitory avoidance. Neuropsychobiology 46:97\u2013103","journal-title":"Neuropsychobiology"},{"key":"1575_CR37","unstructured":"Mathers CD, Boschi-Pinto C, Lopez AD, Murray CJ, Organization WH (2001) Cancer incidence, mortality and survival by site for 14 regions of the world"},{"key":"1575_CR38","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/j.jnutbio.2009.01.013","volume":"21","author":"JD Moreira","year":"2010","unstructured":"Moreira JD, Knorr L, Thomazi AP, Sim\u00e3o F, Batt\u00fa C, Oses JP, Gottfried C, Wofchuk S, Salbego C, Souza DO (2010) Dietary omega-3 fatty acids attenuate cellular damage after a hippocampal ischemic insult in adult rats. J Nutr Biochem 21:351\u2013356","journal-title":"J Nutr Biochem"},{"key":"1575_CR39","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1007\/s11060-014-1657-1","volume":"121","author":"LL Muldoon","year":"2015","unstructured":"Muldoon LL, Wu YJ, Pagel MA, Neuwelt EA (2015) N-acetylcysteine chemoprotection without decreased cisplatin antitumor efficacy in pediatric tumor models. J Neurooncol 121:433\u2013440","journal-title":"J Neurooncol"},{"key":"1575_CR40","first-page":"001","volume":"1","author":"A Mustapha","year":"2022","unstructured":"Mustapha A, Ismail A, Abdullahi SU, Hassan ON, Ugwunnaji PI, Berinyuy EB (2022) Cancer chemotherapy: a review update of the mechanisms of actions, prospects and associated problems. J Biomed 1:001\u201316","journal-title":"J Biomed"},{"key":"1575_CR41","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1007\/s10555-015-9572-2","volume":"34","author":"SF Nabavi","year":"2015","unstructured":"Nabavi SF, Bilotto S, Russo GL, Orhan IE, Habtemariam S, Daglia M, Devi KP, Loizzo MR, Tundis R, Nabavi SM (2015) Omega-3 polyunsaturated fatty acids and cancer: lessons learned from clinical trials. Cancer Metastasis Rev 34:359\u2013380","journal-title":"Cancer Metastasis Rev"},{"key":"1575_CR42","first-page":"25","volume-title":"lncRNAs: significance and function mechanisms","author":"MR Noori-Daloii","year":"2015","unstructured":"Noori-Daloii MR, Eshaghkhani Y (2015) LncRNAs: significance and function mechanisms. Medical Sciences Journal of Islamic Azad University, p 25"},{"key":"1575_CR43","first-page":"1","volume":"68","author":"MR Noori-Daloii","year":"2010","unstructured":"Noori-Daloii MR, Jalilian N (2010) Applications of comparative genomic hybridization in cancer and genetic disorders: a review Article. Tehran Univ Med J 68:1\u201311","journal-title":"Tehran Univ Med J"},{"key":"1575_CR44","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.lmot.2019.01.001","volume":"65","author":"F Nouri","year":"2019","unstructured":"Nouri F, Afarinesh M, Sheibania V, Foroumadi A, Esmaeili Mahani S, Mahmoudi M, Rohani E (2019) Concomitant abuse of methadone and methamphetamine could impair Spatial learning and memory in male rats. Learn Motiv 65:43\u201351","journal-title":"Learn Motiv"},{"key":"1575_CR45","doi-asserted-by":"publisher","first-page":"304","DOI":"10.3390\/antiox4020304","volume":"4","author":"ET Olayinka","year":"2015","unstructured":"Olayinka ET, Ore A, Adeyemo OA, Ola OS, Olotu OO, Echebiri RC (2015) Quercetin, a flavonoid antioxidant, ameliorated procarbazine-induced oxidative damage to murine tissues. Antioxidants 4:304\u2013321","journal-title":"Antioxidants"},{"key":"1575_CR46","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/S0022-2275(20)40232-9","volume":"5","author":"MM Oliveira","year":"1964","unstructured":"Oliveira MM, Vaughan M (1964) Incorporation of fatty acids into phospholipids of erythrocyte membranes. J Lipid Res 5:156\u2013162","journal-title":"J Lipid Res"},{"key":"1575_CR47","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.jelechem.2015.02.033","volume":"746","author":"SCB Oliveira","year":"2015","unstructured":"Oliveira SCB, Mendes CH, Franklin Filho F, Queiroz NL, Nascimento JA, Nascimento VB (2015) Electrochemical oxidation mechanism of procarbazine at glassy carbon electrode. J Electroanal Chem 746:51\u201356","journal-title":"J Electroanal Chem"},{"key":"1575_CR48","first-page":"1","volume-title":"Chemobrain in cancer treatment: Mechanisms and its prevention. handbook of cancer and immunology","author":"B Ongnok","year":"2022","unstructured":"Ongnok B, Thiankhaw K, Chattipakorn N, Chattipakorn SC (2022) Chemobrain in cancer treatment: mechanisms and its prevention. Handbook of cancer and immunology. Springer, pp 1\u201337"},{"key":"1575_CR49","volume-title":"Examining effects of dietary enrichment with omega-3 fatty acids on neuroinflammation, insulin resistance, and cognitive function in a mouse model of chemotherapy","author":"KS Ormiston","year":"2020","unstructured":"Ormiston KS (2020) Examining effects of dietary enrichment with omega-3 fatty acids on neuroinflammation, insulin resistance, and cognitive function in a mouse model of chemotherapy. The Ohio State University"},{"key":"1575_CR50","unstructured":"Paxinos G, Watson C (2007) The rat brain in stereotaxic coordinates, 44\u2013168"},{"key":"1575_CR51","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/j.advms.2020.04.001","volume":"65","author":"C Pellacani","year":"2020","unstructured":"Pellacani C, Eleftheriou G (2020) Neurotoxicity of antineoplastic drugs: mechanisms, susceptibility, and neuroprotective strategies. Adv Med Sci 65:265\u2013285","journal-title":"Adv Med Sci"},{"key":"1575_CR52","doi-asserted-by":"publisher","first-page":"3461","DOI":"10.2147\/PPA.S440148","volume":"17","author":"M Pezzolato","year":"2023","unstructured":"Pezzolato M, Spada GE, Fragale E, Cutica I, Masiero M, Marzorati C, Pravettoni G (2023) Predictive models of psychological distress, quality of life, and adherence to medication in breast cancer patients: A scoping review. Patient Prefer Adherence 17:3461\u20133473","journal-title":"Patient Prefer Adherence"},{"key":"1575_CR53","first-page":"e2021394","volume":"92","author":"H Pourmobini","year":"2021","unstructured":"Pourmobini H, Afarinesh MR, Shamsara A, Eftekhar-Vaghefi SH, Asadi-Shekaari M (2021) Chronically Pre-treatment of pistachio alters the morphology of CA1 hippocampus neurons following transient focal cerebral ischemia in male Wistar rats. Acta Biomed 92:e2021394","journal-title":"Acta Biomed"},{"key":"1575_CR54","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.eurpolymj.2014.05.003","volume":"57","author":"R Quintana","year":"2014","unstructured":"Quintana R, Persenaire O, Lemmouchi Y, Bonnaud L, Dubois P (2014) Grafted D\/L-lactide to cellulose acetate by reactive melt processing: its role as CA\/PLA blend compatibilizer. Eur Polymer J 57:30\u201336","journal-title":"Eur Polymer J"},{"key":"1575_CR55","doi-asserted-by":"publisher","first-page":"6533","DOI":"10.1007\/s00018-021-03925-4","volume":"78","author":"NG Rummel","year":"2021","unstructured":"Rummel NG, Chaiswing L, Bondada S, St. Clair DK, Butterfield DA (2021) Chemotherapy-induced cognitive impairment: focus on the intersection of oxidative stress and TNF\u03b1. Cell Mol Life Sci 78:6533\u20136540","journal-title":"Cell Mol Life Sci"},{"key":"1575_CR56","first-page":"694","volume":"16","author":"A Saberi Moghadam","year":"2013","unstructured":"Saberi Moghadam A, Sepehri G, Sheibani V, Haghpanah T, Divsalar K, Hajzadeh MA, Afarineshkhaki M (2013) The effect of opium dependency of parent (s) on offspring\u2019s Spatial learning & memory in adult male rats. Iran J Basic Med Sci 16:694\u2013699","journal-title":"Iran J Basic Med Sci"},{"key":"1575_CR57","doi-asserted-by":"publisher","first-page":"51","DOI":"10.9734\/jpri\/2022\/v34i18A35785","volume":"34","author":"C Samanta","year":"2022","unstructured":"Samanta C, Tewari S, Chakraborty D, Vaishnav S (2022) Omega-3 fatty acid and its protective effect against cancer and cancer-related complication. J Pharm Res Int 34:51\u201362","journal-title":"J Pharm Res Int"},{"key":"1575_CR58","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.ejcsup.2013.07.007","volume":"11","author":"SB Schagen","year":"2013","unstructured":"Schagen SB, Wefel JS (2013) Chemotherapy-related changes in cognitive functioning. Eur J Cancer Suppl 11:225\u2013232","journal-title":"Eur J Cancer Suppl"},{"key":"1575_CR59","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1016\/j.arr.2004.05.002","volume":"3","author":"F Serrano","year":"2004","unstructured":"Serrano F, Klann E (2004) Reactive oxygen species and synaptic plasticity in the aging hippocampus. Ageing Res Rev 3:431\u2013443","journal-title":"Ageing Res Rev"},{"key":"1575_CR60","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/0003-2697(72)90132-7","volume":"47","author":"AK Sinha","year":"1972","unstructured":"Sinha AK (1972) Colorimetric assay of catalase. Anal Biochem 47:389\u2013394","journal-title":"Anal Biochem"},{"key":"1575_CR61","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1002\/med.21977","volume":"44","author":"M Skurlova","year":"2024","unstructured":"Skurlova M, Holubova K, Kleteckova L, Kozak T, Kubova H, Horacek J, Vales K (2024) Chemobrain in blood cancers: how chemotherapeutics interfere with the brain\u2019s structure and functionality, immune system, and metabolic functions. Med Res Rev 44:5\u201322","journal-title":"Med Res Rev"},{"key":"1575_CR62","doi-asserted-by":"crossref","unstructured":"Soffietti R, Trevisan E, Rud\u00e0 R (2014) Chapter 80\u2014Neurologic complications of chemotherapy and other newer and experimental approaches. In: Biller J, Ferro JM (eds) Handbook of clinical neurology.\u00a0Elsevier, pp 1199\u20131218","DOI":"10.1016\/B978-0-7020-4088-7.00080-8"},{"key":"1575_CR63","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1002\/ijc.32113","volume":"145","author":"M Song","year":"2019","unstructured":"Song M, Ou F-S, Zemla TJ, Hull MA, Shi Q, Limburg PJ, Alberts SR, Sinicrope FA, Giovannucci EL, Van Blarigan EL (2019) Marine omega-3 fatty acid intake and survival of stage III colon cancer according to tumor molecular markers in NCCTG phase III trial N0147 (alliance). Int J Cancer 145:380\u2013389","journal-title":"Int J Cancer"},{"key":"1575_CR64","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4172\/1948-5956.100000e2","volume":"1","author":"A Sudhakar","year":"2009","unstructured":"Sudhakar A (2009) History of cancer, ancient and modern treatment methods. J cancer Sci Therapy 1:1","journal-title":"J cancer Sci Therapy"},{"key":"1575_CR65","first-page":"135","volume":"2","author":"M Taati","year":"2020","unstructured":"Taati M, Habibi Rezaei M, Keihan AH (2020) Omega-3 fatty acids: Anti-inflammatory effects to ensure the health. J Mar Med 2:135\u2013149","journal-title":"J Mar Med"},{"key":"1575_CR66","doi-asserted-by":"publisher","first-page":"100","DOI":"10.7324\/JAPS.2018.8716","volume":"8","author":"M Taheri","year":"2018","unstructured":"Taheri M, Haghpanah T, Meftahi GH, Abedini-Esfahlani M, Gloshan F, Esmailpour K, Znangiabadi I, Masoumi-Ardakani Y, Nouri F, Sheibani V, Afarinesh M (2018) Mild permanent chronic thyroid hormone insufficiency induces cognitive dysfunction in the adult male and female rats. J App Pharm Sci 8:100\u2013106","journal-title":"J App Pharm Sci"},{"key":"1575_CR67","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1016\/0003-2697(69)90064-5","volume":"27","author":"F Tietze","year":"1969","unstructured":"Tietze F (1969) Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem 27:502\u2013522","journal-title":"Anal Biochem"},{"key":"1575_CR68","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.ejcsup.2013.07.009","volume":"11","author":"MD Trill","year":"2013","unstructured":"Trill MD (2013) Anxiety and sleep disorders in cancer patients. Eur J Cancer Suppl 11:216\u2013224","journal-title":"Eur J Cancer Suppl"},{"key":"1575_CR69","doi-asserted-by":"publisher","first-page":"3","DOI":"10.2174\/138161210789941847","volume":"16","author":"A Urruticoechea","year":"2010","unstructured":"Urruticoechea A, Alemany R, Balart J, Villanueva A, Vinals F, Capella G (2010) Recent advances in cancer therapy: an overview. Curr Pharm Design 16:3\u201310","journal-title":"Curr Pharm Design"},{"key":"1575_CR70","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.1038\/s41380-019-0595-x","volume":"25","author":"YH Wang","year":"2019","unstructured":"Wang YH, Li JQ, Shi JF, Que JY, Liu JJ, Lappin JM, Leung J, Ravindran AV, Chen WQ, Qiao YL, Shi J, Lu L, Bao YP (2019) Depression and anxiety in relation to cancer incidence and mortality: a systematic review and meta-analysis of cohort studies. Mol Psychiatry 25:1487\u20131499","journal-title":"Mol Psychiatry"},{"key":"1575_CR71","first-page":"568","volume":"50","author":"JA Ward","year":"1990","unstructured":"Ward JA, Robinson J, Furr BJ, Shalet SM, Morris ID (1990) Protection of spermatogenesis in rats from the cytotoxic procarbazine by the depot formulation of Zoladex, a gonadotropin-releasing hormone agonist. Cancer Res 50:568\u2013574","journal-title":"Cancer Res"},{"key":"1575_CR72","first-page":"1315","volume":"23","author":"G Warwick","year":"1963","unstructured":"Warwick G (1963) The mechanism of action of alkylating agents. Cancer Res 23:1315\u20131333","journal-title":"Cancer Res"},{"key":"1575_CR73","doi-asserted-by":"publisher","first-page":"750507","DOI":"10.3389\/fphar.2022.750507","volume":"13","author":"H Was","year":"2022","unstructured":"Was H, Borkowska A, Bagues A, Tu L, Liu JY, Lu Z, Rudd JA, Nurgali K, Abalo R (2022) Mechanisms of chemotherapy-induced neurotoxicity. Front Pharmacol 13:750507","journal-title":"Front Pharmacol"},{"key":"1575_CR74","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1038\/nprot.2009.197","volume":"5","author":"CJ Weydert","year":"2010","unstructured":"Weydert CJ, Cullen JJ (2010) Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue. Nat Protoc 5:51\u201366","journal-title":"Nat Protoc"},{"key":"1575_CR75","doi-asserted-by":"publisher","first-page":"36615","DOI":"10.1007\/s11356-019-06809-0","volume":"26","author":"I Zangiabadi","year":"2019","unstructured":"Zangiabadi I, Afarinesh MR, Shamsara A, Eftekhar-Vaghefi SH (2019) Movento effects on learning and hippocampal brain-derived neurotrophic factor protein of adult male rats. Environ Sci Pollut Res Int 26:36615\u201336622","journal-title":"Environ Sci Pollut Res Int"},{"key":"1575_CR76","doi-asserted-by":"publisher","first-page":"707","DOI":"10.3389\/fneur.2020.00707","volume":"11","author":"E Zhang","year":"2020","unstructured":"Zhang E, Wan X, Yang L, Wang D, Chen Z, Chen Y, Liu M, Zhang G, Wu J, Han H (2020) Omega-3 polyunsaturated fatty acids alleviate traumatic brain injury by regulating the glymphatic pathway in mice. Front Neurol 11:707","journal-title":"Front Neurol"}],"container-title":["Metabolic Brain Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11011-025-01575-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11011-025-01575-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11011-025-01575-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T12:18:23Z","timestamp":1743337103000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11011-025-01575-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,15]]},"references-count":76,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,3]]}},"alternative-id":["1575"],"URL":"https:\/\/doi.org\/10.1007\/s11011-025-01575-0","relation":{},"ISSN":["1573-7365"],"issn-type":[{"type":"electronic","value":"1573-7365"}],"subject":[],"published":{"date-parts":[[2025,3,15]]},"assertion":[{"value":"16 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 March 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 March 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Animal care protocols were accepted by the Animal Experiment Committee at Kerman University of\u00a0Medical Sciences\u00a0(Ethics code: Ethics code: IR.KMU.AH.REC.1400.114).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"153"}}