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Am J Clin Nutr. https:\/\/doi.org\/10.3945\/ajcn.2009.28449c","journal-title":"Am J Clin Nutr"}],"container-title":["Metabolic Brain Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11011-025-01757-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11011-025-01757-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11011-025-01757-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T22:02:07Z","timestamp":1768082527000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11011-025-01757-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,10]]},"references-count":196,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["1757"],"URL":"https:\/\/doi.org\/10.1007\/s11011-025-01757-w","relation":{},"ISSN":["1573-7365"],"issn-type":[{"value":"1573-7365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,10]]},"assertion":[{"value":"4 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The authors declare no competing financial interests or conflicts of interest relevant to this study.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Financial Disclosures"}},{"value":"Databases:\n                      PubMed, Web of Science, Google Scholar.\n                      Search Terms:\n                      \"Adiponectin AND depression\", \"Adiponectin AND HPA axis\", \"Adiponectin AND neuroinflammation\", \"Adiponectin AND antidepressant\", \"AdipoRon\", etc.\n                      Inclusion Criteria:\n                      Preclinical and clinical studies, English language, focus on mood and mechanistic pathways.\n                      Synthesis:\n                      This narrative review synthesizes evidence to build a comprehensive picture of the topic.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Review Methodology"}},{"value":"Extracted data were analyzed to identify convergent mechanisms and highlight the potential of adiponectin as a biomarker and therapeutic target. The review also explores the effects of lifestyle interventions and existing antidepressants on adiponectin levels.","order":8,"name":"Ethics","group":{"name":"EthicsHeading","label":"Data Synthesis"}}],"article-number":"17"}}