{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T13:57:14Z","timestamp":1765807034469},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2012,2,2]],"date-time":"2012-02-02T00:00:00Z","timestamp":1328140800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Divers"],"published-print":{"date-parts":[[2012,5]]},"DOI":"10.1007\/s11030-012-9359-0","type":"journal-article","created":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T16:06:44Z","timestamp":1328112404000},"page":"291-298","source":"Crossref","is-referenced-by-count":12,"title":["Synthesis of 5-alkylated barbituric acids and 3-alkylated indoles via microwave-assisted three-component reactions in solvent-free conditions using Hantzsch 1,4-dihydropyridines as reducing agents"],"prefix":"10.1007","volume":"16","author":[{"given":"Biswajita","family":"Baruah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. Seetham","family":"Naidu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pallabi","family":"Borah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pulak J.","family":"Bhuyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,2,2]]},"reference":[{"key":"9359_CR1","first-page":"358","volume-title":"The pharmacological basis of therapeutics","author":"LS Goodman","year":"1991","unstructured":"Goodman LS, Gilman A (1991) The pharmacological basis of therapeutics. Mc Graw-Hill, New Delhi, pp 358\u2013360"},{"key":"9359_CR2","first-page":"243","volume-title":"Medical pharmacology","author":"G Andrews","year":"1976","unstructured":"Andrews G (1976) Medical pharmacology. The CV Mosby Co., Saint Louis, MO, pp 243\u2013250"},{"key":"9359_CR3","first-page":"143","volume-title":"Principles of medicinal chemistry","author":"WO Foye","year":"1989","unstructured":"Foye WO (1989) Principles of medicinal chemistry. Lea & Febiger, Pennsylvania, PA, pp 143\u2013237"},{"key":"9359_CR4","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1016\/S0960-894X(99)00238-3","volume":"9","author":"DJ Guerin","year":"1999","unstructured":"Guerin DJ, Mazeas D, Musale MS, Naguib FNM, Safarjalani ONA, Kouni MH, Panzica RP (1999) Uridine phosphorylase inhibitors: chemical modification of benzyloxybenzyl barbituric acid and its effects on UrdPase inhibition. Bioorg Med Chem Lett 9: 1477\u20131480. doi: 10.1016\/S0960-894X(99)00238-3","journal-title":"Bioorg Med Chem Lett"},{"key":"9359_CR5","first-page":"97","volume":"44","author":"E Fisher","year":"1903","unstructured":"Fisher E, Moring JR (1903) Ueber eine neue Klasse von Schlafmitteln. Ther Ggw 44: 97\u2013105","journal-title":"Ther Ggw"},{"key":"9359_CR6","first-page":"164","volume":"4","author":"WJ Doran","year":"1959","unstructured":"Doran WJ (1959) Barbituric acid hypnotics. Med Chem 4: 164\u2013167","journal-title":"Med Chem"},{"key":"9359_CR7","first-page":"231","volume":"31","author":"B Bobranski","year":"1977","unstructured":"Bobranski B (1977) Progress in chemistry of barbituric acid. Wiad Chem 31: 231\u2013278","journal-title":"Wiad Chem"},{"key":"9359_CR8","first-page":"1519","volume":"17","author":"S Senda","year":"1967","unstructured":"Senda S, Izumi H, Fujimura H (1967) Uracil derivatives and related compounds. VI. Derivatives of 5-alkyl-2,4,6-trioxoperhydropyrimidine as anti-inflammatory agents. Arznein Forsch 17: 1519\u20131523","journal-title":"Arznein Forsch"},{"key":"9359_CR9","doi-asserted-by":"crossref","first-page":"2757","DOI":"10.1016\/S0040-4039(00)77025-0","volume":"35","author":"JWG Meissuer","year":"1994","unstructured":"Meissuer JWG, Vander Lean AC, Pandit UK (1994) Reduction of 5-arylidenebarbiturate derivatives by thiols. Tetrahedron Lett 35: 2757\u20132760. doi: 10.1016\/S0040-4039(00)77025-0","journal-title":"Tetrahedron Lett"},{"key":"9359_CR10","doi-asserted-by":"crossref","first-page":"3241","DOI":"10.1016\/S0040-4020(01)85957-3","volume":"44","author":"K Tanaka","year":"1988","unstructured":"Tanaka K, Chen X, Yoneda F (1988) Oxidation of thiol with 5-arylidene-1,3-dimethylbarbituric acid: application to synthesis of unsymmetrical disulfide. Tetrahedron 44: 3241\u20133249. doi: 10.1016\/S0040-4020(01)85957-3","journal-title":"Tetrahedron"},{"key":"9359_CR11","doi-asserted-by":"crossref","first-page":"2250","DOI":"10.1021\/cr900195a","volume":"110","author":"M Shiri","year":"2010","unstructured":"Shiri M, Zolfigol MA, Kruger HG, Tanbakouchain Z (2010) Bis- and trisindolylmethanes (BIMs and TIMs). Chem Rev 110: 2250\u20132293. doi: 10.1021\/cr900195a","journal-title":"Chem Rev"},{"key":"9359_CR12","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1126\/science.1078197","volume":"299","author":"DJ Walter","year":"2003","unstructured":"Walter DJ, Peter J, Basahammakh S, Hortnagl H, Voits M, Fink H, Bader M (2003) Synthesis of serotonin by a second tryptophan hydroxylase isoform. Science 299: 76\u201379. doi: 10.1126\/science.1078197","journal-title":"Science"},{"key":"9359_CR13","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.7164\/antibiotics.45.1681","volume":"45","author":"D Komagata","year":"1992","unstructured":"Komagata D, Sawa R, Kinoshita N, Imada C, Sawa T, Naganawa H, Hamada M, Okami Y, Takeuchi T (1992) Isolation of glutathione- S-transferase inhibitors. J Antibiot 45: 1681\u20131683","journal-title":"J Antibiot"},{"key":"9359_CR14","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1016\/S0040-4020(98)01095-3","volume":"55","author":"A Santamaria","year":"1999","unstructured":"Santamaria A, Cabezas N, Avendano C (1999) Synthesis of tryptophan-dehydrobutyrine diketopiperazines and analogues. Tetrahedron 55: 1173\u20131186. doi: 10.1016\/S0040-4020(98)01095-3","journal-title":"Tetrahedron"},{"key":"9359_CR15","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1002\/hlca.200690026","volume":"89","author":"J Wagger","year":"2006","unstructured":"Wagger J, Bevk D, Meden A, Svete J, Stanovnik B (2006) Enaminone-based synthesis of dipodazine derivatives. Helv Chim Acta 89: 240\u2013248. doi: 10.1002\/hlca.200690026","journal-title":"Helv Chim Acta"},{"key":"9359_CR16","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0065-7743(08)60490-X","volume":"17","author":"H Meyer","year":"1982","unstructured":"Meyer H (1982) Chapter 8. Antianginal and Anti-ischemic Agents. Annu Rep Med Chem 17: 71\u201377. doi: 10.1016\/S0065-7743(08)60490-X","journal-title":"Annu Rep Med Chem"},{"key":"9359_CR17","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1021\/jm00360a001","volume":"26","author":"RA Janis","year":"1983","unstructured":"Janis RA, Triggle DJ (1983) New developments in calcium ion channel antagonists. J Med Chem 26: 775\u2013785. doi: 10.1021\/jm00360a001","journal-title":"J Med Chem"},{"key":"9359_CR18","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0065-7743(08)61119-7","volume":"21","author":"E Wehinger","year":"1986","unstructured":"Wehinger E, Gross R (1986) Chapter 9. Calcium modulators. Annu Rep Med Chem 21: 85\u201394. doi: 10.1016\/S0065-7743(08)61119-7","journal-title":"Annu Rep Med Chem"},{"key":"9359_CR19","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0302-4598(00)00073-8","volume":"51","author":"R Toniolo","year":"2000","unstructured":"Toniolo R, Narda FD, Bontempelli G, Ursini F (2000) An electroanalytical investigation on the redox properties of lacidipine supporting its anti-oxidant effect. Bioelectrochem 51: 193\u2013200. doi: 10.1016\/S0302-4598(00)00073-8","journal-title":"Bioelectrochem"},{"key":"9359_CR20","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1021\/jm00110a012","volume":"34","author":"FP Guengerich","year":"1991","unstructured":"Guengerich FP, Brain WR, Iwasaki M, Sari MA, Berntsson P (1991) Oxidation of dihydropyridine calcium channel blockers and analogs by human liver cytochrome P-450 IIIA4. J Med Chem 34: 1838\u20131844. doi: 10.1021\/jm00110a012","journal-title":"J Med Chem"},{"key":"9359_CR21","unstructured":"The Merck Index (2001) 13th ed. Merck Research Laboratories: New Jersy, NJ, p 6370"},{"key":"9359_CR22","doi-asserted-by":"crossref","first-page":"8158","DOI":"10.1021\/jo000484h","volume":"65","author":"BXQ Zhu","year":"2000","unstructured":"Zhu BXQ, Zhao J, Cheng JP (2000) Mechanisms of the oxidations of NAD(P)H model Hantzsch 1,4-dihydropyridines by nitric oxide and its donor N-Methyl-N-nitrosotoluene-p-sulfonamide. J Org Chem 65: 8158\u20138163. doi: 10.1021\/jo000484h","journal-title":"J Org Chem"},{"key":"9359_CR23","doi-asserted-by":"crossref","first-page":"3440","DOI":"10.1021\/ja037631o","volume":"126","author":"D Zhang","year":"2004","unstructured":"Zhang D, Wu LZ, Zhou L, Han X, Yang LQZ, Zhang P, Tung CH (2004) Photocatalytic hydrogen production from Hantzsch 1,4-dihydropyridines by platinum(II) terpyridyl complexes in homogeneous solution. J Am Chem Soc 126: 3440\u20133441. doi: 10.1021\/ja037631o","journal-title":"J Am Chem Soc"},{"key":"9359_CR24","doi-asserted-by":"crossref","first-page":"2720","DOI":"10.1016\/j.bmc.2005.11.051","volume":"14","author":"M Nasr-Esfahani","year":"2006","unstructured":"Nasr-Esfahani M, Moghadam M, Tangesta-ninejad S, Mirkhani V, Momeni AR (2006) Rapid and efficient oxidation of Hantzsch 1,4-dihydropyridines with sodium periodate catalyzed by manganese (III) Schiff base complexes. Bioorg Med Chem 14: 2720\u20132724. doi: 10.1016\/j.bmc.2005.11.051","journal-title":"Bioorg Med Chem"},{"key":"9359_CR25","doi-asserted-by":"crossref","first-page":"3305","DOI":"10.1016\/j.bmcl.2007.04.002","volume":"17","author":"MM Heravi","year":"2007","unstructured":"Heravi MM, Derkvand F, Pour SH, Bakhitari K, Bamoharram FF, Oskooie HA (2007) Oxidative aromatization of Hantzsch 1,4-dihydropyridines in the presence of mixed-addenda vanadomolybdophosphate heteropolyacid, H6PMo9V3O40. Bioorg Med Chem Lett 17: 3305\u20133309. doi: 10.1016\/j.bmcl.2007.04.002","journal-title":"Bioorg Med Chem Lett"},{"key":"9359_CR26","doi-asserted-by":"crossref","first-page":"8608","DOI":"10.1021\/jo701796n","volume":"72","author":"X Fang","year":"2007","unstructured":"Fang X, Liu YC, Li C (2007) 9-Phenyl-10-methylacridinium: a highly efficient and reusable organocatalyst for mild aromatization of 1,4-dihydropyridines by molecular oxygen. J Org Chem 72: 8608\u20138610. doi: 10.1021\/jo701796n","journal-title":"J Org Chem"},{"key":"9359_CR27","doi-asserted-by":"crossref","first-page":"5649","DOI":"10.1016\/j.tet.2008.04.040","volume":"64","author":"MF Litvic","year":"2008","unstructured":"Litvic MF, Litvic M, Vinkovic V (2008) An efficient, metal-free, room temperature aromatization of Hantzsch-1,4-dihydropyridines with urea\u2013hydrogen peroxide adduct, catalyzed by molecular iodine. Tetrahedron 64: 5649\u20135656. doi: 10.1016\/j.tet.2008.04.040","journal-title":"Tetrahedron"},{"key":"9359_CR28","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1021\/cr940089p","volume":"100","author":"T Tanaka","year":"2000","unstructured":"Tanaka T, Toda F (2000) Solvent-free organic synthesis. Chem Rev 100: 1025\u20131074. doi: 10.1021\/cr940089p","journal-title":"Chem Rev"},{"key":"9359_CR29","doi-asserted-by":"crossref","first-page":"6966","DOI":"10.1021\/jo0005621","volume":"65","author":"M Pourashraf","year":"2000","unstructured":"Pourashraf M, Delair P, Rasmaissen MO, Greene AE (2000) Highly enantioselective approach to indolizidines: preparation of (+)-(1S,8aS)-1-hydroxyindolizidine and (\u2212)slaframine. J Org Chem 65: 6966\u20136972. doi: 10.1021\/jo0005621","journal-title":"J Org Chem"},{"key":"9359_CR30","doi-asserted-by":"crossref","unstructured":"Cossy J, Willis C, Bellosta V, Jalmes LS (2002) Enantioselective sllyltitanation. Synthesis of (\u2212)slaframine. Synthesis 7:951\u2013957. doi: 10.1055\/s-2002-28505","DOI":"10.1055\/s-2002-28505"},{"key":"9359_CR31","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1055\/s-1999-2612","volume":"29","author":"L Weber","year":"1999","unstructured":"Weber L, Illegen K, Almstetter M (1999) Discovery of new multi component reactions with combinatorial methods. Synlett 29: 366\u2013374","journal-title":"Synlett"},{"key":"9359_CR32","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1021\/ar9502083","volume":"29","author":"RW Armstrong","year":"1996","unstructured":"Armstrong RW, Combs AP, Tempest PA, Brown SD, Keating TA (1996) Multiple-component condensation strategies for combinatorial library synthesis. Acc Chem Rev 29: 123\u2013131. doi: 10.1021\/ar9502083","journal-title":"Acc Chem Rev"},{"key":"9359_CR33","doi-asserted-by":"crossref","first-page":"7099","DOI":"10.1016\/j.tet.2009.06.036","volume":"65","author":"B Baruah","year":"2009","unstructured":"Baruah B, Bhuyan PJ (2009) Synthesis of some complex pyrano[2,3-b]- and pyrido[2,3-b]quinolines from simple acetanilides via intramolecular domino hetero Diels\u2013Alder reactions of 1-oxa-1,3-butadienes in aqueous medium. Tetrahedron 65: 7099\u20137104. doi: 10.1016\/j.tet.2009.06.036","journal-title":"Tetrahedron"},{"key":"9359_CR34","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.tetlet.2008.10.125","volume":"50","author":"B Baruah","year":"2009","unstructured":"Baruah B, Bhuyan PJ (2009) Tertiary amine effect: synthesis of some novel spirosubstituted pyrido[2,3-d]pyrimidines. Tetrahedron Lett 50: 243\u2013245. doi: 10.1016\/j.tetlet.2008.10.125","journal-title":"Tetrahedron Lett"},{"key":"9359_CR35","unstructured":"Deb ML, Bhuyan PJ (2008) An efficient method for the synthesis of indolo[3,2-b]-carbazoles from 3,3\u2032-bis(indolyl)methanes catalyzed by molecular iodine. Synlett 3:325\u2013328"},{"key":"9359_CR36","doi-asserted-by":"crossref","unstructured":"Deb ML, Bhuyan PJ (2008) A novel and efficient method for the synthesis of unsymmetrical diindolylmethanes and heterocyclic(indolyl)alkanes. Synthesis 18:2891\u20132898. doi: 10.1055\/s-2008-1067217","DOI":"10.1055\/s-2008-1067217"},{"key":"9359_CR37","doi-asserted-by":"crossref","unstructured":"Deb ML, Baruah B, Bhuyan PJ (2008) A facile synthesis of 6,12-disubstituted 5, 7-dihydroindolo[2,3-b]carbazoles from the reaction of 1H-indole & catalysed by molecular iodine. Synthesis 2:286\u2013292. doi: 10.1055\/s-2008-1000849","DOI":"10.1055\/s-2008-1000849"},{"key":"9359_CR38","doi-asserted-by":"crossref","first-page":"583","DOI":"10.3987\/COM-05-S(K)33","volume":"66","author":"K Yamada","year":"2005","unstructured":"Yamada K, Izumi T, Yamada F, Somei M (2005) Solvent effect on the reaction of 1-methoxy-3-(2-nitrovinyl)indole with nucleophiles. Heterocycles 66: 583\u2013594. doi: 10.3987\/COM-05-S(K)33","journal-title":"Heterocycles"}],"container-title":["Molecular Diversity"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11030-012-9359-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11030-012-9359-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11030-012-9359-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T02:58:24Z","timestamp":1559357904000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11030-012-9359-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2,2]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,5]]}},"alternative-id":["9359"],"URL":"https:\/\/doi.org\/10.1007\/s11030-012-9359-0","relation":{},"ISSN":["1381-1991","1573-501X"],"issn-type":[{"value":"1381-1991","type":"print"},{"value":"1573-501X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,2,2]]}}}