{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T23:18:48Z","timestamp":1783207128505,"version":"3.54.6"},"reference-count":584,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Divers"],"DOI":"10.1007\/s11030-025-11453-7","type":"journal-article","created":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T12:41:33Z","timestamp":1768394493000},"page":"5641-5717","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Integrative gene target mapping, RNA sequencing, in silico molecular docking, ADMET profiling and molecular dynamics simulation study of marine derived molecules for type 1 diabetes mellitus"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2202-7637","authenticated-orcid":false,"given":"Basavaraj","family":"Vastrad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9246-1604","authenticated-orcid":false,"given":"Shivaling","family":"Pattanashetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1054-8996","authenticated-orcid":false,"given":"Veeresh","family":"Sadashivanavar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2017-9533","authenticated-orcid":false,"given":"K. S. R.","family":"Pai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3615-4450","authenticated-orcid":false,"given":"Chanabasayya","family":"Vastrad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,14]]},"reference":[{"issue":"2","key":"11453_CR1","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1503\/cmaj.060244","volume":"175","author":"KM Gillespie","year":"2006","unstructured":"Gillespie KM (2006) Type 1 diabetes: pathogenesis and prevention. CMAJ 175(2):165\u2013170. https:\/\/doi.org\/10.1503\/cmaj.060244","journal-title":"CMAJ"},{"issue":"3","key":"11453_CR2","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/j.ecl.2010.05.011","volume":"39","author":"DM Maahs","year":"2010","unstructured":"Maahs DM, West NA, Lawrence JM, Mayer-Davis EJ (2010) Epidemiology of type 1 diabetes. Endocrinol Metab Clin North Am 39(3):481\u2013497. https:\/\/doi.org\/10.1016\/j.ecl.2010.05.011","journal-title":"Endocrinol Metab Clin North Am"},{"key":"11453_CR3","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.999108","volume":"13","author":"J Zhang","year":"2022","unstructured":"Zhang J, Xiao Y, Hu J, Liu S, Zhou Z, Xie L (2022) Lipid metabolism in type 1 diabetes mellitus: pathogenetic and therapeutic implications. Front Immunol 13:999108. https:\/\/doi.org\/10.3389\/fimmu.2022.999108","journal-title":"Front Immunol"},{"issue":"5","key":"11453_CR4","doi-asserted-by":"publisher","first-page":"438","DOI":"10.2174\/1573399815666191004112647","volume":"16","author":"S Desai","year":"2020","unstructured":"Desai S, Deshmukh A (2020) Mapping of type 1 diabetes mellitus. Curr Diabetes Rev 16(5):438\u2013441. https:\/\/doi.org\/10.2174\/1573399815666191004112647","journal-title":"Curr Diabetes Rev"},{"key":"11453_CR5","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.mito.2023.07.002","volume":"72","author":"AV Blagov","year":"2023","unstructured":"Blagov AV, Summerhill VI, Sukhorukov VN, Popov MA, Grechko AV, Orekhov AN (2023) Type 1 diabetes mellitus: inflammation, mitophagy, and mitochondrial function. Mitochondrion 72:11\u201321. https:\/\/doi.org\/10.1016\/j.mito.2023.07.002","journal-title":"Mitochondrion"},{"issue":"12","key":"11453_CR6","doi-asserted-by":"publisher","first-page":"1579","DOI":"10.1134\/S0006297921120075","volume":"86","author":"EG Novoselova","year":"2021","unstructured":"Novoselova EG, Glushkova OV, Khrenov MO, Lunin SM, Novoselova TV, Parfenuyk SB (2021) Role of innate immunity and oxidative stress in the development of type 1 diabetes mellitus. Peroxiredoxin 6 as a new anti-diabetic agent. Biochemistry (Mosc) 86(12):1579\u20131589. https:\/\/doi.org\/10.1134\/S0006297921120075","journal-title":"Biochemistry (Mosc)"},{"issue":"8","key":"11453_CR7","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1001\/jama.2017.0686","volume":"317","author":"D Dabelea","year":"2017","unstructured":"Dabelea D, Stafford JM, Mayer-Davis EJ, D\u2019Agostino R Jr, Dolan L, Imperatore G, Linder B, Lawrence JM, Marcovina SM, Mottl AK et al (2017) Association of type 1 diabetes vs type 2 diabetes diagnosed during childhood and adolescence with complications during teenage years and young adulthood. JAMA 317(8):825\u2013835. https:\/\/doi.org\/10.1001\/jama.2017.0686","journal-title":"JAMA"},{"key":"11453_CR8","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/2987901","volume":"2019","author":"K Wang","year":"2019","unstructured":"Wang K, Li F, Cui Y, Cui C, Cao Z, Xu K, Han S, Zhu P, Sun Y (2019) The association between depression and type 1 diabetes mellitus: inflammatory cytokines as ferrymen in between? Mediat Inflamm 2019:2987901. https:\/\/doi.org\/10.1155\/2019\/2987901","journal-title":"Mediat Inflamm"},{"issue":"4","key":"11453_CR9","doi-asserted-by":"publisher","DOI":"10.1136\/bmjdrc-2024-004024","volume":"12","author":"S Satuli-Autere","year":"2024","unstructured":"Satuli-Autere S, Harjutsalo V, Eriksson MI, H\u00e4gg-Holmberg S, \u00d6hman H, Claesson TB, Groop PH, Thorn LM, FinnDiane Study Group (2024) Increased incidence of neurodegenerative diseases in Finnish individuals with type 1 diabetes. BMJ Open Diabetes Res Care 12(4):e004024. https:\/\/doi.org\/10.1136\/bmjdrc-2024-004024","journal-title":"BMJ Open Diabetes Res Care"},{"key":"11453_CR10","doi-asserted-by":"publisher","first-page":"2807","DOI":"10.2147\/DMSO.S223618","volume":"14","author":"N Vilarrasa","year":"2021","unstructured":"Vilarrasa N, San Jose P, Rubio M\u00c1, Lecube A (2021) Obesity in patients with type 1 diabetes: links, risks and mana ent challenges. Diabetes Metab Syndr Obes 14:2807\u20132827. https:\/\/doi.org\/10.2147\/DMSO.S223618","journal-title":"Diabetes Metab Syndr Obes"},{"issue":"8","key":"11453_CR11","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1093\/ajh\/hpz058","volume":"32","author":"G Ponirakis","year":"2019","unstructured":"Ponirakis G, Petropoulos IN, Alam U, Ferdousi M, Asghar O, Marshall A, Azmi S, Jeziorska M, Mahfoud ZR, Boulton AJM et al (2019) Hypertension contributes to neuropathy in patients with type 1 diabetes. Am J Hypertens 32(8):796\u2013803. https:\/\/doi.org\/10.1093\/ajh\/hpz058","journal-title":"Am J Hypertens"},{"issue":"8","key":"11453_CR12","doi-asserted-by":"publisher","first-page":"1798","DOI":"10.3390\/jcm10081798","volume":"10","author":"C Colom","year":"2021","unstructured":"Colom C, Rull A, Sanchez-Quesada JL, P\u00e9rez A (2021) Cardiovascular Disease in Type 1 Diabetes Mellitus: epidemiology and management of cardiovascular risk. J Clin Med 10(8):1798. https:\/\/doi.org\/10.3390\/jcm10081798","journal-title":"J Clin Med"},{"issue":"12","key":"11453_CR13","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics11122267","volume":"11","author":"NH Chowdhury","year":"2021","unstructured":"Chowdhury NH, Reaz MBI, Haque F, Ahmad S, Ali SHM, A Bakar AA, Bhuiyan MAS (2021) Performance analysis of conventional machine learning algorithms for identification of chronic kidney disease in type 1 diabetes mellitus patients. Diagnostics 11(12):2267. https:\/\/doi.org\/10.3390\/diagnostics11122267","journal-title":"Diagnostics"},{"issue":"2","key":"11453_CR14","doi-asserted-by":"publisher","DOI":"10.3390\/metabo11020069","volume":"11","author":"C Mameli","year":"2021","unstructured":"Mameli C, Ghezzi M, Mari A, Cammi G, Macedoni M, Redaelli FC, Calcaterra V, Zuccotti G, D\u2019Auria E (2021) The diabetic lung: insights into pulmonary changes in children and adolescents with type 1 diabetes. Metabolites 11(2):69. https:\/\/doi.org\/10.3390\/metabo11020069","journal-title":"Metabolites"},{"key":"11453_CR15","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.1031633","volume":"13","author":"P Memaj","year":"2022","unstructured":"Memaj P, Jornayvaz FR (2022) Non-alcoholic fatty liver disease in type 1 diabetes: prevalence and pathophysiology. Front Endocrinol (Lausanne) 13:1031633","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"11","key":"11453_CR16","doi-asserted-by":"publisher","first-page":"1785","DOI":"10.4103\/njcp.njcp_1985_21","volume":"25","author":"S Dereci","year":"2022","unstructured":"Dereci S, Hizli S, Bolu S, Asik A, Direkci I, Karadag AS (2022) Evaluation of eye health in children with type 1 diabetes mellitus and celiac disease. Niger J Clin Pract 25(11):1785\u20131791. https:\/\/doi.org\/10.4103\/njcp.njcp_1985_21","journal-title":"Niger J Clin Pract"},{"issue":"3","key":"11453_CR17","doi-asserted-by":"publisher","DOI":"10.3390\/jpm13030422","volume":"13","author":"MS Popoviciu","year":"2023","unstructured":"Popoviciu MS, Kaka N, Sethi Y, Patel N, Chopra H, Cavalu S (2023) Type 1 Diabetes Mellitus and Autoimmune Diseases: a critical review of the association and the application of personalized medicine. J Pers Med 13(3):422. https:\/\/doi.org\/10.3390\/jpm13030422","journal-title":"J Pers Med"},{"key":"11453_CR18","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/174186","volume":"2015","author":"TS Khan","year":"2015","unstructured":"Khan TS, Fraser LA (2015) Type 1 diabetes and osteoporosis: from molecular pathways to bone phenotype. J Osteoporos 2015:174186. https:\/\/doi.org\/10.1155\/2015\/174186","journal-title":"J Osteoporos"},{"issue":"10","key":"11453_CR19","doi-asserted-by":"publisher","first-page":"1394","DOI":"10.2337\/dc17-0681","volume":"40","author":"S H\u00e4gg-Holmberg","year":"2017","unstructured":"H\u00e4gg-Holmberg S, Thorn LM, Forsblom CM, Gordin D, Elonen N, Harjutsalo V, Liebkind R, Putaala J, Tatlisumak T, Groop PH et al (2017) Prognosis and its predictors after incident stroke in patients with type 1 diabetes. Diabetes Care 40(10):1394\u20131400. https:\/\/doi.org\/10.2337\/dc17-0681","journal-title":"Diabetes Care"},{"issue":"7","key":"11453_CR20","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1038\/nrendo.2017.39","volume":"13","author":"C Mathieu","year":"2017","unstructured":"Mathieu C, Gillard P, Benhalima K (2017) Insulin analogues in type 1 diabetes mellitus: getting better all the time. Nat Rev Endocrinol 13(7):385\u2013399. https:\/\/doi.org\/10.1038\/nrendo.2017.39","journal-title":"Nat Rev Endocrinol"},{"issue":"11","key":"11453_CR21","doi-asserted-by":"publisher","first-page":"3901","DOI":"10.2337\/db13-0236","volume":"62","author":"W Hagopian","year":"2013","unstructured":"Hagopian W, Ferry RJ Jr, Sherry N, Carlin D, Bonvini E, Johnson S, Stein KE, Koenig S, Daifotis AG, Herold KC et al (2013) Teplizumab preserves C-peptide in recent-onset type 1 diabetes: two-year results from the randomized, placebo-controlled Prot\u00e9g\u00e9 trial. Diabetes 62(11):3901\u20133908. https:\/\/doi.org\/10.2337\/db13-0236","journal-title":"Diabetes"},{"issue":"6","key":"11453_CR22","doi-asserted-by":"publisher","DOI":"10.1007\/s11892-016-0739-1","volume":"16","author":"CJ Dwyer","year":"2016","unstructured":"Dwyer CJ, Ward NC, Pugliese A, Malek TR (2016) Promoting immune regulation in type 1 diabetes using low-dose interleukin-2. Curr Diab Rep 16(6):46. https:\/\/doi.org\/10.1007\/s11892-016-0739-1","journal-title":"Curr Diab Rep"},{"issue":"1","key":"11453_CR23","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/S2213-8587(18)30109-8","volume":"7","author":"BO Roep","year":"2019","unstructured":"Roep BO, Wheeler DCS, Peakman M (2019) Antigen-based immune modulation therapy for type 1 diabetes: the era of precision medicine. Lancet Diabetes Endocrinol 7(1):65\u201374. https:\/\/doi.org\/10.1016\/S2213-8587(18)30109-8","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"3","key":"11453_CR24","doi-asserted-by":"publisher","first-page":"101S","DOI":"10.1177\/0145721706288S237","volume":"32","author":"C Martin","year":"2006","unstructured":"Martin C (2006) The physiology of amylin and insulin: maintaining the balance between glucose secretion and glucose uptake. Diabetes Educ 32(3):101S-104S. https:\/\/doi.org\/10.1177\/0145721706288S237","journal-title":"Diabetes Educ"},{"issue":"1","key":"11453_CR25","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.cmet.2017.04.011","volume":"26","author":"E Ferrannini","year":"2017","unstructured":"Ferrannini E (2017) Sodium-glucose co-transporters and their inhibition: clinical physiology. Cell Metab 26(1):27\u201338. https:\/\/doi.org\/10.1016\/j.cmet.2017.04.011","journal-title":"Cell Metab"},{"issue":"1","key":"11453_CR26","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1111\/dom.13162","volume":"20","author":"VR Aroda","year":"2018","unstructured":"Aroda VR (2018) A review of GLP-1 receptor agonists: evolution and advancement, through the lens of randomised controlled trials. Diabetes Obes Metab 20(1):22\u201333. https:\/\/doi.org\/10.1111\/dom.13162","journal-title":"Diabetes Obes Metab"},{"issue":"4","key":"11453_CR27","doi-asserted-by":"publisher","first-page":"848","DOI":"10.2337\/db11-0955","volume":"61","author":"G Xu","year":"2012","unstructured":"Xu G, Chen J, Jing G, Shalev A (2012) Preventing \u03b2-cell loss and diabetes with calcium channel blockers. Diabetes 61(4):848\u2013856. https:\/\/doi.org\/10.2337\/db11-0955","journal-title":"Diabetes"},{"issue":"1","key":"11453_CR28","doi-asserted-by":"publisher","first-page":"9157","DOI":"10.1038\/s41598-022-13291-1","volume":"12","author":"M Pujar","year":"2022","unstructured":"Pujar M, Vastrad B, Kavatagimath S, Vastrad C, Kotturshetti S (2022) Identification of candidate biomarkers and pathways associated with type 1 diabetes mellitus using bioinformatics analysis. Sci Rep 12(1):9157. https:\/\/doi.org\/10.1038\/s41598-022-13291-1","journal-title":"Sci Rep"},{"issue":"1","key":"11453_CR29","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-021-00709-6","volume":"21","author":"G Prashanth","year":"2021","unstructured":"Prashanth G, Vastrad B, Tengli A, Vastrad C, Kotturshetti I (2021) Identification of hub genes related to the progression of type 1 diabetes by computational analysis. BMC Endocr Disord 21(1):61. https:\/\/doi.org\/10.1186\/s12902-021-00709-6","journal-title":"BMC Endocr Disord"},{"issue":"1","key":"11453_CR30","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1093\/aje\/kwi165","volume":"162","author":"FK Kavvoura","year":"2005","unstructured":"Kavvoura FK, Ioannidis JP (2005) CTLA-4 gene polymorphisms and susceptibility to type 1 diabetes mellitus: a HuGE review and meta-analysis. Am J Epidemiol 162(1):3\u201316. https:\/\/doi.org\/10.1093\/aje\/kwi165","journal-title":"Am J Epidemiol"},{"issue":"2","key":"11453_CR31","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/s00439-006-0309-8","volume":"121","author":"R Ni","year":"2007","unstructured":"Ni R, Ihara K, Miyako K, Kuromaru R, Inuo M, Kohno H, Hara T (2007) PD-1 gene haplotype is associated with the development of type 1 diabetes mellitus in Japanese children. Hum Genet 121(2):223\u2013232. https:\/\/doi.org\/10.1007\/s00439-006-0309-8","journal-title":"Hum Genet"},{"issue":"7153","key":"11453_CR32","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1038\/nature06010","volume":"448","author":"H Hakonarson","year":"2007","unstructured":"Hakonarson H, Grant SF, Bradfield JP, Marchand L, Kim CE, Glessner JT, Grabs R, Casalunovo T, Taback SP, Frackelton EC et al (2007) A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. Nature 448(7153):591\u2013594. https:\/\/doi.org\/10.1038\/nature06010","journal-title":"Nature"},{"issue":"10","key":"11453_CR33","doi-asserted-by":"publisher","first-page":"2616","DOI":"10.2337\/db07-0652","volume":"56","author":"R Bailey","year":"2007","unstructured":"Bailey R, Cooper JD, Zeitels L, Smyth DJ, Yang JH, Walker NM, Hypp\u00f6nen E, Dunger DB, Ramos-Lopez E, Badenhoop K et al (2007) Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes. Diabetes 56(10):2616\u20132621. https:\/\/doi.org\/10.2337\/db07-0652","journal-title":"Diabetes"},{"issue":"7171","key":"11453_CR34","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1038\/nature06406","volume":"450","author":"S Nejentsev","year":"2007","unstructured":"Nejentsev S, Howson JM, Walker NM, Szeszko J, Field SF, Stevens HE, Reynolds P, Hardy M, King E, Masters J et al (2007) Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. Nature 450(7171):887\u2013892. https:\/\/doi.org\/10.1038\/nature06406","journal-title":"Nature"},{"issue":"4","key":"11453_CR35","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1111\/1753-0407.13252","volume":"14","author":"I Camaya","year":"2022","unstructured":"Camaya I, Donnelly S, O\u2019Brien B (2022) Targeting the PI3K\/Akt signaling pathway in pancreatic \u03b2-cells to enhance their survival and function: an emerging therapeutic strategy for type 1 diabetes. J Diabetes 14(4):247\u2013260. https:\/\/doi.org\/10.1111\/1753-0407.13252","journal-title":"J Diabetes"},{"issue":"2","key":"11453_CR36","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/j.fct.2009.11.004","volume":"48","author":"C Kang","year":"2010","unstructured":"Kang C, Jin YB, Lee H, Cha M, Sohn ET, Moon J, Park C, Chun S, Jung ES, Hong JS et al (2010) Brown alga Ecklonia cava attenuates type 1 diabetes by activating AMPK and Akt signaling pathways. Food Chem Toxicol 48(2):509\u2013516. https:\/\/doi.org\/10.1016\/j.fct.2009.11.004","journal-title":"Food Chem Toxicol"},{"issue":"2","key":"11453_CR37","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1007\/s00210-020-01979-y","volume":"394","author":"AA Gbr","year":"2021","unstructured":"Gbr AA, Abdel Baky NA, Mohamed EA, Zaky HS (2021) Cardioprotective effect of pioglitazone and curcumin against diabetic cardiomyopathy in type 1 diabetes mellitus: impact on CaMKII\/NF-\u03baB\/TGF-\u03b21 and PPAR-\u03b3 signaling pathway. Naunyn Schmiedebergs Arch Pharmacol 394(2):349\u2013360. https:\/\/doi.org\/10.1007\/s00210-020-01979-y","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"issue":"1","key":"11453_CR38","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/s11596-020-2144-x","volume":"40","author":"JJ Liu","year":"2020","unstructured":"Liu JJ, Shentu LM, Ma N, Wang LY, Zhang GM, Sun Y, Wang Y, Li J, Mu YL (2020) Inhibition of NF-\u03baB and Wnt\/\u03b2-catenin\/GSK3\u03b2 signaling pathways ameliorates cardiomyocyte hypertrophy and fibrosis in streptozotocin (STZ)-induced type 1 diabetic rats. Curr Med Sci 40(1):35\u201347. https:\/\/doi.org\/10.1007\/s11596-020-2144-x","journal-title":"Curr Med Sci"},{"issue":"5","key":"11453_CR39","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1016\/j.jnutbio.2012.04.013","volume":"24","author":"V Soetikno","year":"2013","unstructured":"Soetikno V, Sari FR, Sukumaran V, Lakshmanan AP, Harima M, Suzuki K, Kawachi H, Watanabe K (2013) Curcumin decreases renal triglyceride accumulation through AMPK-SREBP signaling pathway in streptozotocin-induced type 1 diabetic rats. J Nutr Biochem 24(5):796\u2013802. https:\/\/doi.org\/10.1016\/j.jnutbio.2012.04.013","journal-title":"J Nutr Biochem"},{"key":"11453_CR40","doi-asserted-by":"publisher","DOI":"10.1101\/2024.12.16.628242","author":"X Liu","year":"2024","unstructured":"Liu X, Dos Santos T, Spigelman AF, Duckett S, Smith N, Suzuki K, MacDonald PE (2024) TMEM55A-mediated PI5P signaling regulates \u03b1-cell actin depolymerization and glucagon secretion. bioRxiv. https:\/\/doi.org\/10.1101\/2024.12.16.628242","journal-title":"bioRxiv"},{"key":"11453_CR41","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1007\/978-1-4939-3578-9_5","volume":"1418","author":"E Clough","year":"2016","unstructured":"Clough E, Barrett T (2016) The gene expression omnibus database. Methods Mol Biol 1418:93\u2013110. https:\/\/doi.org\/10.1007\/978-1-4939-3578-9_5","journal-title":"Methods Mol Biol"},{"issue":"12","key":"11453_CR42","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-014-0550-8","volume":"15","author":"MI Love","year":"2014","unstructured":"Love MI, Huber W, Anders S (2014) Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol 15(12):550. https:\/\/doi.org\/10.1186\/s13059-014-0550-8","journal-title":"Genome Biol"},{"issue":"issue","key":"11453_CR43","doi-asserted-by":"publisher","first-page":"W193","DOI":"10.1093\/nar\/gkm226","volume":"35","author":"J Reimand","year":"2007","unstructured":"Reimand J, Kull M, Peterson H, Hansen J, Vilo J (2007) g:Profiler--a web-based toolset for functional profiling of gene lists from large-scale experiments. Nucleic Acids Res 35(issue):W193\u2013W200. https:\/\/doi.org\/10.1093\/nar\/gkm226","journal-title":"Nucleic Acids Res"},{"key":"11453_CR44","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/978-1-4939-3743-1_2","volume":"1446","author":"PD Thomas","year":"2017","unstructured":"Thomas PD (2017) The gene ontology and the meaning of biological function. Methods Mol Biol 1446:15\u201324. https:\/\/doi.org\/10.1007\/978-1-4939-3743-1_2","journal-title":"Methods Mol Biol"},{"issue":"D1","key":"11453_CR45","doi-asserted-by":"publisher","first-page":"D649","DOI":"10.1093\/nar\/gkx1132","volume":"46","author":"A Fabregat","year":"2018","unstructured":"Fabregat A, Jupe S, Matthews L, Sidiropoulos K, Gillespie M, Garapati P, Haw R, Jassal B, Korninger F, May B et al (2018) The reactome pathway knowledgebase. Nucleic Acids Res 46(D1):D649\u2013D655. https:\/\/doi.org\/10.1093\/nar\/gkx1132","journal-title":"Nucleic Acids Res"},{"issue":"D1","key":"11453_CR46","doi-asserted-by":"publisher","first-page":"D640","DOI":"10.1093\/nar\/gkab1034","volume":"50","author":"M Kotlyar","year":"2022","unstructured":"Kotlyar M, Pastrello C, Ahmed Z, Chee J, Varyova Z, Jurisica I (2022) IID 2021: towards context-specific protein interaction analyses by increased coverage, enhanced annotation and enrichment analysis. Nucleic Acids Res 50(D1):D640\u2013D647. https:\/\/doi.org\/10.1093\/nar\/gkab1034","journal-title":"Nucleic Acids Res"},{"issue":"W1","key":"11453_CR47","doi-asserted-by":"publisher","first-page":"W203","DOI":"10.1093\/nar\/gkaf365","volume":"53","author":"K Ono","year":"2025","unstructured":"Ono K, Fong D, Gao C, Churas C, Pillich R, Lenkiewicz J, Pratt D, Pico AR, Hanspers K, Xin Y et al (2025) Cytoscape web: bringing network biology to the browser. Nucleic Acids Res 53(W1):W203\u2013W212. https:\/\/doi.org\/10.1093\/nar\/gkaf365","journal-title":"Nucleic Acids Res"},{"key":"11453_CR48","doi-asserted-by":"publisher","first-page":"2011","DOI":"10.2147\/NDT.S142742","volume":"13","author":"X Luo","year":"2017","unstructured":"Luo X, Guo L, Dai XJ, Wang Q, Zhu W, Miao X, Gong H (2017) Abnormal intrinsic functional hubs in alcohol dependence: evidence from a voxelwise degree centrality analysis. Neuropsychiatr Dis Treat 13:2011\u20132020. https:\/\/doi.org\/10.2147\/NDT.S142742","journal-title":"Neuropsychiatr Dis Treat"},{"key":"11453_CR49","doi-asserted-by":"publisher","DOI":"10.1038\/srep46491","volume":"7","author":"Y Li","year":"2017","unstructured":"Li Y, Li W, Tan Y, Liu F, Cao Y, Lee KY (2017) Hierarchical decomposition for betweenness centrality measure of complex networks. Sci Rep 7:46491. https:\/\/doi.org\/10.1038\/srep46491","journal-title":"Sci Rep"},{"key":"11453_CR50","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2021.104114","volume":"235","author":"M Gilbert","year":"2021","unstructured":"Gilbert M, Li Z, Wu XN, Rohr L, Gombos S, Harter K, Schulze WX (2021) Comparison of path-based centrality measures in protein-protein interaction networks revealed proteins with phenotypic relevance during adaptation to changing nitrogen environments. J Proteomics 235:104114. https:\/\/doi.org\/10.1016\/j.jprot.2021.104114","journal-title":"J Proteomics"},{"issue":"4","key":"11453_CR51","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1109\/TCBB.2018.2889978","volume":"17","author":"G Li","year":"2020","unstructured":"Li G, Li M, Wang J, Li Y, Pan Y (2020) United neighborhood closeness centrality and orthology for predicting essential proteins. IEEE ACM Trans Comput Biol Bioinform 17(4):1451\u20131458. https:\/\/doi.org\/10.1109\/TCBB.2018.2889978","journal-title":"IEEE ACM Trans Comput Biol Bioinform"},{"key":"11453_CR52","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-14","volume":"14","author":"N Zaki","year":"2013","unstructured":"Zaki N, Efimov D, Berengueres J (2013) Protein complex detection using interaction reliability assessment and weighted clustering coefficient. BMC Bioinform 14:163. https:\/\/doi.org\/10.1186\/1471-2105-14","journal-title":"BMC Bioinform"},{"key":"11453_CR53","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1007\/978-1-4939-8618-7_10","volume":"1819","author":"Y Fan","year":"2018","unstructured":"Fan Y, Xia J (2018) miRNet-functional analysis and visual exploration of miRNA-target interactions in a network context. Methods Mol Biol 1819:215\u2013233. https:\/\/doi.org\/10.1007\/978-1-4939-8618-7_10","journal-title":"Methods Mol Biol"},{"key":"11453_CR54","doi-asserted-by":"publisher","first-page":"W234","DOI":"10.1093\/nar\/gkz240","volume":"47","author":"G Zhou","year":"2019","unstructured":"Zhou G, Soufan O, Ewald J, Hancock REW, Basu N, Xia J (2019) NetworkAnalyst 3.0: a visual analytics platform for comprehensive gene expression profiling and meta-analysis. Nucleic Acids Res 47:W234\u2013W241. https:\/\/doi.org\/10.1093\/nar\/gkz240","journal-title":"Nucleic Acids Res"},{"key":"11453_CR55","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-12-77","volume":"12","author":"X Robin","year":"2011","unstructured":"Robin X, Turck N, Hainard A, Tiberti N, Lisacek F, Sanchez JC, M\u00fcller M (2011) pROC: an open-source package for R and S+ to analyze and compare ROC curves. BMC Bioinform 12:77. https:\/\/doi.org\/10.1186\/1471-2105-12-77","journal-title":"BMC Bioinform"},{"issue":"1","key":"11453_CR56","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1038\/nrg2918","volume":"12","author":"AL Barab\u00e1si","year":"2011","unstructured":"Barab\u00e1si AL, Gulbahce N, Loscalzo J (2011) Network medicine: a network-based approach to human disease. Nat Rev Genet 12(1):56\u201368. https:\/\/doi.org\/10.1038\/nrg2918","journal-title":"Nat Rev Genet"},{"issue":"43","key":"11453_CR57","doi-asserted-by":"publisher","first-page":"15545","DOI":"10.1073\/pnas.0506580102","volume":"102","author":"A Subramanian","year":"2005","unstructured":"Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES et al (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 102(43):15545\u201315550. https:\/\/doi.org\/10.1073\/pnas.0506580102","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"D1","key":"11453_CR58","doi-asserted-by":"publisher","first-page":"D523","DOI":"10.1093\/nar\/gkac1052","volume":"51","author":"UniProt Consortium","year":"2023","unstructured":"UniProt Consortium (2023) UniProt: the Universal Protein Knowledgebase in 2023. Nucleic Acids Res 51(D1):D523\u2013D531. https:\/\/doi.org\/10.1093\/nar\/gkac1052","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"11453_CR59","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1093\/nar\/28.1.235","volume":"28","author":"HM Berman","year":"2000","unstructured":"Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE (2000) The protein data bank. Nucleic Acids Res 28(1):235\u2013242. https:\/\/doi.org\/10.1093\/nar\/28.1.235","journal-title":"Nucleic Acids Res"},{"issue":"4","key":"11453_CR60","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1002\/jcc.21643","volume":"32","author":"D Plewczynski","year":"2011","unstructured":"Plewczynski D, \u0141a\u017aniewski M, Augustyniak R, Ginalski K (2011) Can we trust docking results? Evaluation of seven commonly used programs on PDBbind database. J Comput Chem 32(4):742\u2013755. https:\/\/doi.org\/10.1002\/jcc.21643","journal-title":"J Comput Chem"},{"issue":"D1","key":"11453_CR61","doi-asserted-by":"publisher","first-page":"D945","DOI":"10.1093\/nar\/gkw1074","volume":"45","author":"A Gaulton","year":"2017","unstructured":"Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibri\u00e1n-Uhalte E et al (2017) The ChEMBL database in 2017. Nucleic Acids Res 45(D1):D945\u2013D954. https:\/\/doi.org\/10.1093\/nar\/gkw1074","journal-title":"Nucleic Acids Res"},{"issue":"issue","key":"11453_CR62","doi-asserted-by":"publisher","first-page":"D198","DOI":"10.1093\/nar\/gkl999","volume":"35","author":"T Liu","year":"2007","unstructured":"Liu T, Lin Y, Wen X, Jorissen RN, Gilson MK (2007) BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities. Nucleic Acids Res 35(issue):D198\u2013D201. https:\/\/doi.org\/10.1093\/nar\/gkl999","journal-title":"Nucleic Acids Res"},{"issue":"W1","key":"11453_CR63","doi-asserted-by":"publisher","first-page":"W363","DOI":"10.1093\/nar\/gky473","volume":"46","author":"W Tian","year":"2018","unstructured":"Tian W, Chen C, Lei X, Zhao J, Liang J (2018) CASTp 3.0: computed atlas of surface topography of proteins. Nucleic Acids Res 46(W1):W363\u2013W367. https:\/\/doi.org\/10.1093\/nar\/gky473","journal-title":"Nucleic Acids Res"},{"key":"11453_CR64","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-10-168","volume":"10","author":"V Le Guilloux","year":"2009","unstructured":"Le Guilloux V, Schmidtke P, Tuffery P (2009) Fpocket: an open-source platform for ligand pocket detection. BMC Bioinform 10:168. https:\/\/doi.org\/10.1186\/1471-2105-10-168","journal-title":"BMC Bioinform"},{"issue":"5","key":"11453_CR65","doi-asserted-by":"publisher","first-page":"822","DOI":"10.1021\/ci100026x","volume":"50","author":"IJ Chen","year":"2010","unstructured":"Chen IJ, Foloppe N (2010) Drug-like bioactive structures and conformational coverage with the LigPrep\/ConfGen suite: comparison to programs MOE and catalyst. J Chem Inf Model 50(5):822\u2013839. https:\/\/doi.org\/10.1021\/ci100026x","journal-title":"J Chem Inf Model"},{"issue":"1","key":"11453_CR66","doi-asserted-by":"publisher","DOI":"10.1186\/s13065-024-01317-w","volume":"18","author":"A Mili","year":"2024","unstructured":"Mili A, Birangal S, Giridhar J, Nandakumar K, Lobo R (2024) Identification of phytomolecules as isoform and mutation specific PI3K-\u03b1 inhibitor for protection against breast cancer using e-pharmacophore modeling and molecular dynamics simulations. BMC Chem 18(1):241. https:\/\/doi.org\/10.1186\/s13065-024-01317-w","journal-title":"BMC Chem"},{"issue":"6","key":"11453_CR67","doi-asserted-by":"publisher","DOI":"10.3390\/ph17060725","volume":"17","author":"D Klimoszek","year":"2024","unstructured":"Klimoszek D, Jele\u0144 M, Do\u0142owy M, Morak-M\u0142odawska B (2024) Study of the lipophilicity and ADMET parameters of new anticancer diquinothiazines with pharmacophore substituents. Pharmaceuticals (Basel) 17(6):725. https:\/\/doi.org\/10.3390\/ph17060725","journal-title":"Pharmaceuticals (Basel)"},{"issue":"5","key":"11453_CR68","doi-asserted-by":"publisher","first-page":"958","DOI":"10.1021\/ci800004w","volume":"48","author":"CR Guimar\u00e3es","year":"2008","unstructured":"Guimar\u00e3es CR, Cardozo M (2008) MM-GB\/SA rescoring of docking poses in structure-based lead optimization. J Chem Inf Model 48(5):958\u2013970. https:\/\/doi.org\/10.1021\/ci800004w","journal-title":"J Chem Inf Model"},{"issue":"16","key":"11453_CR69","doi-asserted-by":"publisher","first-page":"9478","DOI":"10.1021\/acs.chemrev.9b00055","volume":"119","author":"E Wang","year":"2019","unstructured":"Wang E, Sun H, Wang J, Wang Z, Liu H, Zhang JZH, Hou T (2019) End-point binding free energy calculation with MM\/PBSA and MM\/GBSA: strategies and applications in drug design. Chem Rev 119(16):9478\u20139508. https:\/\/doi.org\/10.1021\/acs.chemrev.9b00055","journal-title":"Chem Rev"},{"issue":"1","key":"11453_CR70","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1111\/j.1747-0285.2005.00327.x","volume":"67","author":"W Sherman","year":"2006","unstructured":"Sherman W, Beard HS, Farid R (2006) Use of an induced fit receptor structure in virtual screening. Chem Biol Drug Des 67(1):83\u201384. https:\/\/doi.org\/10.1111\/j.1747-0285.2005.00327.x","journal-title":"Chem Biol Drug Des"},{"issue":"2","key":"11453_CR71","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1021\/jm050540c","volume":"49","author":"W Sherman","year":"2006","unstructured":"Sherman W, Day T, Jacobson MP, Friesner RA, Farid R (2006) Novel procedure for modeling ligand\/receptor induced fit effects. J Med Chem 49(2):534\u2013553. https:\/\/doi.org\/10.1021\/jm050540c","journal-title":"J Med Chem"},{"issue":"1","key":"11453_CR72","doi-asserted-by":"publisher","DOI":"10.3390\/molecules30010100","volume":"30","author":"A Saadabadi","year":"2024","unstructured":"Saadabadi A, Wilkman L, Rantanen M, Koivisto AP, Salo-Ahen OMH (2024) Structure- and ligand-based virtual screening for identification of novel TRPV4 antagonists. Molecules 30(1):100. https:\/\/doi.org\/10.3390\/molecules30010100","journal-title":"Molecules"},{"issue":"3","key":"11453_CR73","doi-asserted-by":"publisher","first-page":"1528","DOI":"10.1021\/acs.jcim.9b00843","volume":"60","author":"L Fusani","year":"2020","unstructured":"Fusani L, Palmer DS, Somers DO, Wall ID (2020) Exploring ligand stability in protein crystal structures using binding pose metadynamics. J Chem Inf Model 60(3):1528\u20131539. https:\/\/doi.org\/10.1021\/acs.jcim.9b00843","journal-title":"J Chem Inf Model"},{"issue":"7","key":"11453_CR74","doi-asserted-by":"publisher","first-page":"2695","DOI":"10.1021\/ja512751q","volume":"137","author":"L Wang","year":"2015","unstructured":"Wang L, Wu Y, Deng Y, Kim B, Pierce L, Krilov G, Lupyan D, Robinson S, Dahlgren MK, Greenwood J et al (2015) Accurate and reliable prediction of relative ligand binding potency in prospective drug discovery by way of a modern free-energy calculation protocol and force field. J Am Chem Soc 137(7):2695\u20132703. https:\/\/doi.org\/10.1021\/ja512751q","journal-title":"J Am Chem Soc"},{"issue":"4","key":"11453_CR75","doi-asserted-by":"publisher","first-page":"2014","DOI":"10.1021\/acs.jcim.4c01947","volume":"65","author":"C Li","year":"2025","unstructured":"Li C, Du H, Zhang C, Huang W, Zhang X, Wang T, Jiang D, Hou T, Wang E (2025) Comprehensive evaluation of end-point free energy methods in DNA-ligand interaction predictions. J Chem Inf Model 65(4):2014\u20132025. https:\/\/doi.org\/10.1021\/acs.jcim.4c01947","journal-title":"J Chem Inf Model"},{"issue":"23","key":"11453_CR76","doi-asserted-by":"publisher","first-page":"3093","DOI":"10.2174\/0929867043363929","volume":"11","author":"P Cozzini","year":"2004","unstructured":"Cozzini P, Fornabaio M, Marabotti A, Abraham DJ, Kellogg GE, Mozzarelli A (2004) Free energy of ligand binding to protein: evaluation of the contribution of water molecules by computational methods. Curr Med Chem 11(23):3093\u20133118. https:\/\/doi.org\/10.2174\/0929867043363929","journal-title":"Curr Med Chem"},{"issue":"3","key":"11453_CR77","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1016\/j.jsb.2016.09.003","volume":"196","author":"DJ Huggins","year":"2016","unstructured":"Huggins DJ (2016) Studying the role of cooperative hydration in stabilizing folded protein states. J Struct Biol 196(3):394\u2013406. https:\/\/doi.org\/10.1016\/j.jsb.2016.09.003","journal-title":"J Struct Biol"},{"issue":"5","key":"11453_CR78","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1006\/jmbi.1999.3218","volume":"293","author":"S Kumar","year":"1999","unstructured":"Kumar S, Nussinov R (1999) Salt bridge stability in monomeric proteins. J Mol Biol 293(5):1241\u20131255. https:\/\/doi.org\/10.1006\/jmbi.1999.3218","journal-title":"J Mol Biol"},{"key":"11453_CR79","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2022.133104","volume":"390","author":"N Xia","year":"2022","unstructured":"Xia N, Wang C, Zhu S (2022) Interaction between pH-shifted ovalbumin and insoluble neohesperidin: experimental and binding mechanism studies. Food Chem 390:133104. https:\/\/doi.org\/10.1016\/j.foodchem.2022.133104","journal-title":"Food Chem"},{"issue":"7","key":"11453_CR80","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27072105","volume":"27","author":"HAL Filipe","year":"2022","unstructured":"Filipe HAL, Loura LMS (2022) Molecular dynamics simulations: advances and applications. Molecules 27(7):2105. https:\/\/doi.org\/10.3390\/molecules27072105","journal-title":"Molecules"},{"issue":"6","key":"11453_CR81","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1016\/j.neuron.2018.08.011","volume":"99","author":"SA Hollingsworth","year":"2018","unstructured":"Hollingsworth SA, Dror RO (2018) Molecular dynamics simulation for all. Neuron 99(6):1129\u20131143. https:\/\/doi.org\/10.1016\/j.neuron.2018.08.011","journal-title":"Neuron"},{"issue":"7","key":"11453_CR82","doi-asserted-by":"publisher","first-page":"4047","DOI":"10.1021\/acs.jctc.1c01214","volume":"18","author":"D Jones","year":"2022","unstructured":"Jones D, Allen JE, Yang Y, Drew Bennett WF, Gokhale M, Moshiri N, Rosing TS (2022) Accelerators for classical molecular dynamics simulations of biomolecules. J Chem Theory Comput 18(7):4047\u20134069. https:\/\/doi.org\/10.1021\/acs.jctc.1c01214","journal-title":"J Chem Theory Comput"},{"issue":"9","key":"11453_CR83","doi-asserted-by":"publisher","first-page":"4035","DOI":"10.1021\/acs.jmedchem.5b01684","volume":"59","author":"M De Vivo","year":"2016","unstructured":"De Vivo M, Masetti M, Bottegoni G, Cavalli A (2016) Role of molecular dynamics and related methods in drug discovery. J Med Chem 59(9):4035\u20134061. https:\/\/doi.org\/10.1021\/acs.jmedchem.5b01684","journal-title":"J Med Chem"},{"issue":"6","key":"11453_CR84","doi-asserted-by":"publisher","first-page":"2653","DOI":"10.1021\/acs.jcim.0c00319","volume":"60","author":"RE Amaro","year":"2020","unstructured":"Amaro RE, Mulholland AJ (2020) A community letter regarding sharing biomolecular simulation data for COVID-19. J Chem Inf Model 60(6):2653\u20132656. https:\/\/doi.org\/10.1021\/acs.jcim.0c00319","journal-title":"J Chem Inf Model"},{"issue":"14","key":"11453_CR85","doi-asserted-by":"publisher","first-page":"5061","DOI":"10.1021\/jm100112j","volume":"53","author":"C Bissantz","year":"2010","unstructured":"Bissantz C, Kuhn B, Stahl M (2010) A medicinal chemist\u2019s guide to molecular interactions. J Med Chem 53(14):5061\u20135084. https:\/\/doi.org\/10.1021\/jm100112j","journal-title":"J Med Chem"},{"issue":"27","key":"11453_CR86","doi-asserted-by":"publisher","first-page":"7512","DOI":"10.1021\/acs.langmuir.5b00236","volume":"31","author":"S Parimal","year":"2015","unstructured":"Parimal S, Garde S, Cramer SM (2015) Interactions of multimodal ligands with proteins: insights into selectivity using molecular dynamics simulations. Langmuir 31(27):7512\u20137523. https:\/\/doi.org\/10.1021\/acs.langmuir.5b00236","journal-title":"Langmuir"},{"issue":"11","key":"11453_CR87","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1080\/15257770.2023.2215839","volume":"42","author":"MA Hosen","year":"2023","unstructured":"Hosen MA, Qais FA, Chtita S, Rahman IA, Almehdi AM, Ali F, Almalki FA, Hadda TB, Laaroussi H, Kawsar SMA (2023) In silico and POM analysis for potential antimicrobial agents of thymidine analogs by using molecular docking, molecular dynamics and ADMET profiling. Nucleosides Nucleotides Nucleic Acids 42(11):877\u2013918. https:\/\/doi.org\/10.1080\/15257770.2023.2215839","journal-title":"Nucleosides Nucleotides Nucleic Acids"},{"issue":"11","key":"11453_CR88","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.2174\/138955752411240402134719","volume":"24","author":"IJ Dos Santos Nascimento","year":"2024","unstructured":"Dos Santos Nascimento IJ, de Moura RO (2024) Molecular dynamics simulations in drug discovery. Mini Rev Med Chem 24(11):1061\u20131062. https:\/\/doi.org\/10.2174\/138955752411240402134719","journal-title":"Mini Rev Med Chem"},{"issue":"9","key":"11453_CR89","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1038\/s41574-023-00853-0","volume":"19","author":"MJ Redondo","year":"2023","unstructured":"Redondo MJ, Morgan NG (2023) Heterogeneity and endotypes in type 1 diabetes mellitus. Nat Rev Endocrinol 19(9):542\u2013554. https:\/\/doi.org\/10.1038\/s41574-023-00853-0","journal-title":"Nat Rev Endocrinol"},{"issue":"11","key":"11453_CR90","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1038\/s41574-019-0254-y","volume":"15","author":"J Ilonen","year":"2019","unstructured":"Ilonen J, Lempainen J, Veijola R (2019) The heterogeneous pathogenesis of type 1 diabetes mellitus. Nat Rev Endocrinol 15(11):635\u2013650. https:\/\/doi.org\/10.1038\/s41574-019-0254-y","journal-title":"Nat Rev Endocrinol"},{"issue":"1","key":"11453_CR91","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1038\/ng.493","volume":"42","author":"C Wallace","year":"2010","unstructured":"Wallace C, Smyth DJ, Maisuria-Armer M, Walker NM, Todd JA, Clayton DG (2010) The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes. Nat Genet 42(1):68\u201371. https:\/\/doi.org\/10.1038\/ng.493","journal-title":"Nat Genet"},{"issue":"3","key":"11453_CR92","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0093053","volume":"9","author":"JF Paulsson","year":"2014","unstructured":"Paulsson JF, Ludvigsson J, Carlsson A, Casas R, Forsander G, Ivarsson SA, Kockum I, Lernmark \u00c5, Marcus C, Lindblad B et al (2014) High plasma levels of islet amyloid polypeptide in young with new-onset of type 1 diabetes mellitus. PLoS ONE 9(3):e93053. https:\/\/doi.org\/10.1371\/journal.pone.0093053","journal-title":"PLoS ONE"},{"issue":"2","key":"11453_CR93","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1007\/s00125-005-0100-8","volume":"49","author":"EB Tsai","year":"2006","unstructured":"Tsai EB, Sherry NA, Palmer JP, Herold KC (2006) The rise and fall of insulin secretion in type 1 diabetes mellitus. Diabetologia 49(2):261\u2013270. https:\/\/doi.org\/10.1007\/s00125-005-0100-8","journal-title":"Diabetologia"},{"issue":"5","key":"11453_CR94","doi-asserted-by":"publisher","first-page":"831","DOI":"10.2337\/diabetes.47.5.831","volume":"47","author":"P Vafiadis","year":"1998","unstructured":"Vafiadis P, Grabs R, Goodyer CG, Colle E, Polychronakos C (1998) A functional analysis of the role of IGF2 in IDDM2-encoded susceptibility to type 1 diabetes. Diabetes 47(5):831\u2013836. https:\/\/doi.org\/10.2337\/diabetes.47.5.831","journal-title":"Diabetes"},{"issue":"9","key":"11453_CR95","doi-asserted-by":"publisher","first-page":"2237","DOI":"10.3390\/cells10092237","volume":"10","author":"Y Okano","year":"2021","unstructured":"Okano Y, Takeshita A, Yasuma T, Toda M, Nishihama K, Fridman D\u2019Alessandro V, Inoue C, D\u2019Alessandro-Gabazza CN, Kobayashi T, Yano Y et al (2021) Protective role of recombinant human thrombomodulin in diabetes mellitus. Cells 10(9):2237. https:\/\/doi.org\/10.3390\/cells10092237","journal-title":"Cells"},{"issue":"6","key":"11453_CR96","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1111\/j.1399-5448.2009.00604.x","volume":"11","author":"J Huber","year":"2010","unstructured":"Huber J, Fr\u00f6hlich-Reiterer EE, Sudi K, Suppan E, Weinhandl G, Jasser-Nitsche H, Aigner R, Borkenstein MH (2010) The influence of physical activity on ghrelin and IGF-1\/IGFBP-3 levels in children and adolescents with type 1 diabetes mellitus. Pediatr Diabetes 11(6):383\u2013385. https:\/\/doi.org\/10.1111\/j.1399-5448.2009.00604.x","journal-title":"Pediatr Diabetes"},{"issue":"8","key":"11453_CR97","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9082579","volume":"9","author":"C Hern\u00e1ndez","year":"2020","unstructured":"Hern\u00e1ndez C, Arroba AI, Bogdanov P, Ramos H, Sim\u00f3-Servat O, Sim\u00f3 R, Valverde AM (2020) Effect of topical administration of somatostatin on retinal inflammation and neurodegeneration in an experimental model of diabetes. J Clin Med 9(8):2579. https:\/\/doi.org\/10.3390\/jcm9082579","journal-title":"J Clin Med"},{"issue":"4","key":"11453_CR98","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1086\/342731","volume":"71","author":"Z Hassan","year":"2002","unstructured":"Hassan Z, Mohan V, Ali L, Allotey R, Barakat K, Faruque MO, Deepa R, McDermott MF, Jackson AE, Cassell P et al (2002) SPINK1 is a susceptibility gene for fibrocalculous pancreatic diabetes in subjects from the Indian subcontinent. Am J Hum Genet 71(4):964\u2013968. https:\/\/doi.org\/10.1086\/342731","journal-title":"Am J Hum Genet"},{"key":"11453_CR99","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.peptides.2017.11.005","volume":"100","author":"RA Lafferty","year":"2018","unstructured":"Lafferty RA, Flatt PR, Irwin N (2018) Emerging therapeutic potential for peptide YY for obesity-diabetes. Peptides 100:269\u2013274. https:\/\/doi.org\/10.1016\/j.peptides.2017.11.005","journal-title":"Peptides"},{"issue":"1","key":"11453_CR100","doi-asserted-by":"publisher","first-page":"112","DOI":"10.2337\/db22-0194","volume":"72","author":"X Tang","year":"2023","unstructured":"Tang X, Wang J, Abboud HE, Chen Y, Wang JJ, Zhang SX (2023) Sustained upregulation of endothelial Nox4 mediates retinal vascular pathology in type 1 diabetes. Diabetes 72(1):112\u2013125. https:\/\/doi.org\/10.2337\/db22-0194","journal-title":"Diabetes"},{"issue":"1","key":"11453_CR101","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1007\/s10266-024-00979-1","volume":"113","author":"Y Hong","year":"2025","unstructured":"Hong Y, Xu L, Yu X, He Y, Du Y (2025) DLK1 regulates periodontal inflammation by inhibiting NF-\u03baB p65 and JNK signaling pathways. Odontology 113(1):349\u2013357. https:\/\/doi.org\/10.1007\/s10266-024-00979-1","journal-title":"Odontology"},{"issue":"9","key":"11453_CR102","doi-asserted-by":"publisher","first-page":"1884","DOI":"10.1007\/s00125-014-3304-y","volume":"57","author":"DT Meier","year":"2014","unstructured":"Meier DT, Morcos M, Samarasekera T, Zraika S, Hull RL, Kahn SE (2014) Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice. Diabetologia 57(9):1884\u20131888. https:\/\/doi.org\/10.1007\/s00125-014-3304-y","journal-title":"Diabetologia"},{"issue":"10","key":"11453_CR103","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1007\/s00109-023-02370-z","volume":"101","author":"D Freiholtz","year":"2023","unstructured":"Freiholtz D, Bergman O, Pradhananga S, L\u00e5ng K, Poujade FA, Granath C, Olsson C, Franco-Cereceda A, Sahl\u00e9n P, Eriksson P et al (2023) SPP1\/osteopontin: a driver of fibrosis and inflammation in degenerative ascending aortic aneurysm? J Mol Med (Berl) 101(10):1323\u20131333. https:\/\/doi.org\/10.1007\/s00109-023-02370-z","journal-title":"J Mol Med (Berl)"},{"issue":"2","key":"11453_CR104","doi-asserted-by":"publisher","first-page":"204","DOI":"10.4103\/aja202487","volume":"27","author":"JG Wu","year":"2025","unstructured":"Wu JG, Zhou CP, Gui WW, Liang ZY, Zhang FB, Fu YG, Li R, Wu F, Lin XH (2025) Correlation of IGF2 levels with sperm quality, inflammation, and DNA damage in infertile patients. Asian J Androl 27(2):204\u2013210. https:\/\/doi.org\/10.4103\/aja202487","journal-title":"Asian J Androl"},{"issue":"1","key":"11453_CR105","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1007\/s00281-011-0282-8","volume":"34","author":"EM Conway","year":"2012","unstructured":"Conway EM (2012) Thrombomodulin and its role in inflammation. Semin Immunopathol 34(1):107\u2013125. https:\/\/doi.org\/10.1007\/s00281-011-0282-8","journal-title":"Semin Immunopathol"},{"issue":"1","key":"11453_CR106","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1111\/cen.12241","volume":"80","author":"J Lohr","year":"2014","unstructured":"Lohr J, Grotevendt A, Nauck M, V\u00f6lzke H, Wallaschofski H, Friedrich N (2014) Relation of insulin-like growth factor-I and IGF binding protein 3 with markers of inflammation: results of a population-based study. Clin Endocrinol (Oxf) 80(1):148\u2013154. https:\/\/doi.org\/10.1111\/cen.12241","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"12","key":"11453_CR107","doi-asserted-by":"publisher","first-page":"3222","DOI":"10.1016\/j.jid.2022.06.021","volume":"142","author":"S Kamiya","year":"2022","unstructured":"Kamiya S, Ikegami I, Yanagi M, Takaki H, Kamekura R, Sato T, Kobayashi K, Kamiya T, Kamada Y, Abe T et al (2022) Functional interplay between IL-9 and peptide YY contributes to chronic skin inflammation. J Invest Dermatol 142(12):3222-3231.e5. https:\/\/doi.org\/10.1016\/j.jid.2022.06.021","journal-title":"J Invest Dermatol"},{"issue":"9","key":"11453_CR108","doi-asserted-by":"publisher","first-page":"2863","DOI":"10.7150\/thno.81240","volume":"13","author":"J Li","year":"2023","unstructured":"Li J, Wang L, Wang B, Zhang Z, Jiang L, Qin Z, Zhao Y, Su B (2023) NOX4 is a potential therapeutic target in septic acute kidney injury by inhibiting mitochondrial dysfunction and inflammation. Theranostics 13(9):2863\u20132878. https:\/\/doi.org\/10.7150\/thno.81240","journal-title":"Theranostics"},{"issue":"9","key":"11453_CR109","doi-asserted-by":"publisher","first-page":"1807","DOI":"10.2337\/db17-0682","volume":"67","author":"V Kameswaran","year":"2018","unstructured":"Kameswaran V, Golson ML, Ramos-Rodr\u00edguez M, Ou K, Wang YJ, Zhang J, Pasquali L, Kaestner KH (2018) The dysregulation of the DLK1-MEG3 locus in islets from patients with type 2 diabetes is mimicked by targeted epimutation of its promoter with TALE-DNMT constructs. Diabetes 67(9):1807\u20131815. https:\/\/doi.org\/10.2337\/db17-0682","journal-title":"Diabetes"},{"issue":"1","key":"11453_CR110","doi-asserted-by":"publisher","DOI":"10.1186\/s13098-023-01082-1","volume":"15","author":"M Alrouji","year":"2023","unstructured":"Alrouji M, Al-Kuraishy HM, Al-Gareeb AI, Alexiou A, Papadakis M, Saad HM, Batiha GE (2023) The potential role of human islet amyloid polypeptide in type 2 diabetes mellitus and Alzheimer\u2019s diseases. Diabetol Metab Syndr 15(1):101. https:\/\/doi.org\/10.1186\/s13098-023-01082-1","journal-title":"Diabetol Metab Syndr"},{"issue":"5","key":"11453_CR111","doi-asserted-by":"publisher","first-page":"1770","DOI":"10.3390\/ijms21051770","volume":"21","author":"N Rachdaoui","year":"2020","unstructured":"Rachdaoui N (2020) Insulin: the friend and the foe in the development of type 2 diabetes mellitus. Int J Mol Sci 21(5):1770. https:\/\/doi.org\/10.3390\/ijms21051770","journal-title":"Int J Mol Sci"},{"issue":"1","key":"11453_CR112","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-64857-0","volume":"14","author":"S Xiao","year":"2024","unstructured":"Xiao S, Wang XB, Yang Y, Wang Q (2024) Diagnostic role of SPP1 and collagen IV in a rat model of type 2 diabetes mellitus with MASLD. Sci Rep 14(1):13943. https:\/\/doi.org\/10.1038\/s41598-024-64857-0","journal-title":"Sci Rep"},{"issue":"11","key":"11453_CR113","doi-asserted-by":"publisher","first-page":"2903","DOI":"10.2337\/db17-0187","volume":"66","author":"JM Mercader","year":"2017","unstructured":"Mercader JM, Liao RG, Bell AD, Dymek Z, Estrada K, Tukiainen T, Huerta-Chagoya A, Moreno-Mac\u00edas H, Jablonski KA, Hanson RL et al (2017) A loss-of-function splice acceptor variant in IGF2 is protective for type 2 diabetes. Diabetes 66(11):2903\u20132914. https:\/\/doi.org\/10.2337\/db17-0187","journal-title":"Diabetes"},{"key":"11453_CR114","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2023.101867","volume":"79","author":"A Dance","year":"2024","unstructured":"Dance A, Fernandes J, Toussaint B, Vaillant E, Boutry R, Baron M, Loiselle H, Balkau B, Charpentier G, Franc S et al (2024) Xploring the role of purinergic receptor P2RY1 in type 2 diabetes risk and pathophysiology: insights from human functional genomics. Mol Metab 79:101867. https:\/\/doi.org\/10.1016\/j.molmet.2023.101867","journal-title":"Mol Metab"},{"key":"11453_CR115","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2024.1444279","volume":"15","author":"B Liu","year":"2024","unstructured":"Liu B, Wang Y (2024) Predictive value of IGF-1\/IGFBP-3 ratio for thyroid nodules in type 2 diabetic mellitus. Front Endocrinol (Lausanne) 15:1444279. https:\/\/doi.org\/10.3389\/fendo.2024.1444279","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"4","key":"11453_CR116","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24043449","volume":"24","author":"L Kothegala","year":"2023","unstructured":"Kothegala L, Miranda C, Singh M, Krieger JP, Gandasi NR (2023) Somatostatin containing \u03b4-cell number is reduced in type-2 diabetes. Int J Mol Sci 24(4):3449. https:\/\/doi.org\/10.3390\/ijms24043449","journal-title":"Int J Mol Sci"},{"issue":"6","key":"11453_CR117","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1111\/j.1464-5491.2005.01513.x","volume":"22","author":"A Schneider","year":"2005","unstructured":"Schneider A, Lawrence EC, Barmada MM, Norris JM, Hamman RF, Marshall JA, Ferrell RE, Whitcomb DC (2005) The SPINK1 N34S mutation is not associated with type 2 diabetes mellitus in a population of the USA. Diabet Med 22(6):744\u2013748. https:\/\/doi.org\/10.1111\/j.1464-5491.2005.01513.x","journal-title":"Diabet Med"},{"key":"11453_CR118","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2023.106808","volume":"140","author":"W Chen","year":"2023","unstructured":"Chen W, Binbin G, Lidan S, Qiang Z, Jing H (2023) Evolution of peptide YY analogs for the management of type 2 diabetes and obesity. Bioorg Chem 140:106808. https:\/\/doi.org\/10.1016\/j.bioorg.2023.106808","journal-title":"Bioorg Chem"},{"issue":"7","key":"11453_CR119","doi-asserted-by":"publisher","first-page":"e811","DOI":"10.1111\/aos.13769","volume":"96","author":"W Meng","year":"2018","unstructured":"Meng W, Shah KP, Pollack S, Toppila I, Hebert HL, McCarthy MI, Groop L, Ahlqvist E, Lyssenko V, Agardh E et al (2018) A genome-wide association study suggests new evidence for an association of the NADPH oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes. Acta Ophthalmol 96(7):e811\u2013e819. https:\/\/doi.org\/10.1111\/aos.13769","journal-title":"Acta Ophthalmol"},{"issue":"12","key":"11453_CR120","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci10120975","volume":"10","author":"T Harris","year":"2020","unstructured":"Harris T, Bugescu R, Kelly J, Makela A, Sotzen M, Sisk C, Atkin G, Pratt R, Crockett E, Leinninger G (2020) DLK1 expressed in mouse orexin neurons modulates anxio-depressive behavior but not energy balance. Brain Sci 10(12):975. https:\/\/doi.org\/10.3390\/brainsci10120975","journal-title":"Brain Sci"},{"issue":"5","key":"11453_CR121","doi-asserted-by":"publisher","DOI":"10.1111\/cpr.12806","volume":"53","author":"XH Zou","year":"2020","unstructured":"Zou XH, Sun LH, Yang W, Li BJ, Cui RJ (2020) Potential role of insulin on the pathogenesis of depression. Cell Prolif 53(5):e12806. https:\/\/doi.org\/10.1111\/cpr.12806","journal-title":"Cell Prolif"},{"issue":"1","key":"11453_CR122","doi-asserted-by":"publisher","DOI":"10.1186\/1868-7083-3-2","volume":"3","author":"A Soubry","year":"2011","unstructured":"Soubry A, Murphy S, Huang Z, Murtha A, Schildkraut J, Jirtle R, Wang F, Kurtzberg J, Demark-Wahnefried W, Forman M et al (2011) The effects of depression and use of antidepressive medicines during pregnancy on the methylation status of the IGF2 imprinted control regions in the offspring. Clin Epigenetics 3(1):2. https:\/\/doi.org\/10.1186\/1868-7083-3-2","journal-title":"Clin Epigenetics"},{"issue":"3","key":"11453_CR123","doi-asserted-by":"publisher","first-page":"223","DOI":"10.21101\/cejph.a4301","volume":"24","author":"S Mahmood","year":"2016","unstructured":"Mahmood S, Evinov\u00e1 A, \u0160kere\u0148ov\u00e1 M, Ondrejka I, Lehotsk\u00fd J (2016) Association of EGF, IGFBP-3 and TP53 gene polymorphisms with major depressive disorder in Slovak population. Cent Eur J Public Health 24(3):223\u2013230. https:\/\/doi.org\/10.21101\/cejph.a4301","journal-title":"Cent Eur J Public Health"},{"issue":"8","key":"11453_CR124","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1016\/j.biopsych.2017.05.024","volume":"82","author":"C Fee","year":"2017","unstructured":"Fee C, Banasr M, Sibille E (2017) Somatostatin-positive gamma-aminobutyric acid interneuron deficits in depression: cortical microcircuit and therapeutic perspectives. Biol Psychiatry 82(8):549\u2013559. https:\/\/doi.org\/10.1016\/j.biopsych.2017.05.024","journal-title":"Biol Psychiatry"},{"issue":"3","key":"11453_CR125","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpsgos.2024.100294","volume":"4","author":"II Chan","year":"2024","unstructured":"Chan II, Wu AMS (2024) Assessing the role of cortisol in anxiety, major depression, and neuroticism: a Mendelian randomization study using SERPINA6\/SERPINA1 variants. Biol Psychiatry Glob Open Sci 4(3):100294. https:\/\/doi.org\/10.1016\/j.bpsgos.2024.100294","journal-title":"Biol Psychiatry Glob Open Sci"},{"issue":"2","key":"11453_CR126","doi-asserted-by":"publisher","DOI":"10.3390\/nu13020598","volume":"13","author":"M Tyszkiewicz-Nwafor","year":"2021","unstructured":"Tyszkiewicz-Nwafor M, Jowik K, Dutkiewicz A, Krasinska A, Pytlinska N, Dmitrzak-Weglarz M, Suminska M, Pruciak A, Skowronska B, Slopien A (2021) Neuropeptide Y and peptide YY in association with depressive symptoms and eating behaviours in adolescents across the weight spectrum: from anorexia nervosa to obesity. Nutrients 13(2):598. https:\/\/doi.org\/10.3390\/nu13020598","journal-title":"Nutrients"},{"issue":"6","key":"11453_CR127","doi-asserted-by":"publisher","DOI":"10.3390\/ph16060848","volume":"16","author":"HH Arab","year":"2023","unstructured":"Arab HH, Khames A, Mohammad MK, Alsufyani SE, Ashour AM, El-Sheikh AAK, Darwish HW, Gad AM (2023) Meloxicam targets COX-2\/NOX1\/NOX4\/Nrf2 axis to ameliorate the depression-like neuropathology induced by chronic restraint stress in rats. Pharmaceuticals (Basel) 16(6):848. https:\/\/doi.org\/10.3390\/ph16060848","journal-title":"Pharmaceuticals (Basel)"},{"key":"11453_CR128","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.1033179","volume":"13","author":"S Palumbo","year":"2022","unstructured":"Palumbo S, Umano GR, Aiello F, Cirillo G, Miraglia Del Giudice E, Grandone A (2022) Circulating levels of DLK1 and glucose homeostasis in girls with obesity: a pilot study. Front Endocrinol (Lausanne) 13:1033179. https:\/\/doi.org\/10.3389\/fendo.2022.1033179","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"7","key":"11453_CR129","doi-asserted-by":"publisher","first-page":"2158","DOI":"10.2337\/diabetes.51.7.2158","volume":"51","author":"JG Geisler","year":"2002","unstructured":"Geisler JG, Zawalich W, Zawalich K, Lakey JR, Stukenbrok H, Milici AJ, Soeller WC (2002) Estrogen can prevent or reverse obesity and diabetes in mice expressing human islet amyloid polypeptide. Diabetes 51(7):2158\u20132169. https:\/\/doi.org\/10.2337\/diabetes.51.7.2158","journal-title":"Diabetes"},{"issue":"7","key":"11453_CR130","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1038\/nm.4350","volume":"23","author":"MP Czech","year":"2017","unstructured":"Czech MP (2017) Insulin action and resistance in obesity and type 2 diabetes. Nat Med 23(7):804\u2013814. https:\/\/doi.org\/10.1038\/nm.4350","journal-title":"Nat Med"},{"issue":"7","key":"11453_CR131","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25073966","volume":"25","author":"J Szydlowska-Gladysz","year":"2024","unstructured":"Szydlowska-Gladysz J, Gorecka AE, Stepien J, Rysz I, Ben-Skowronek I (2024) IGF-1 and IGF-2 as molecules linked to causes and consequences of obesity from fetal life to adulthood: a systematic review. Int J Mol Sci 25(7):3966. https:\/\/doi.org\/10.3390\/ijms25073966","journal-title":"Int J Mol Sci"},{"issue":"2","key":"11453_CR132","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1007\/s00431-022-04731-1","volume":"182","author":"D Haldrup","year":"2023","unstructured":"Haldrup D, Wei C, Holland-Fischer P, Kristensen K, Rittig S, Lange A, H\u00f8rlyck A, Solvig J, Gr\u00f8nb\u00e6k H, Birkeb\u00e6k NH et al (2023) Effects of lifestyle intervention on IGF-1, IGFBP-3, and insulin resistance in children with obesity with or without metabolic-associated fatty liver disease. Eur J Pediatr 182(2):855\u2013865. https:\/\/doi.org\/10.1007\/s00431-022-04731-1","journal-title":"Eur J Pediatr"},{"issue":"7","key":"11453_CR133","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21072568","volume":"21","author":"U Kumar","year":"2020","unstructured":"Kumar U, Singh S (2020) Role of somatostatin in the regulation of central and peripheral factors of satiety and obesity. Int J Mol Sci 21(7):2568. https:\/\/doi.org\/10.3390\/ijms21072568","journal-title":"Int J Mol Sci"},{"key":"11453_CR134","doi-asserted-by":"publisher","DOI":"10.1530\/EDM-22-0273","author":"MK Abass","year":"2022","unstructured":"Abass MK, Al Shamsi A, Jan I, Masalawala MSY, Deeb A (2022) Combined SPINK1 mutations induce early-onset severe chronic pancreatitis in a child with severe obesity. Endocrinol Diabetes Metab Case Rep. https:\/\/doi.org\/10.1530\/EDM-22-0273","journal-title":"Endocrinol Diabetes Metab Case Rep"},{"issue":"3","key":"11453_CR135","doi-asserted-by":"publisher","DOI":"10.1172\/JCI162533","volume":"134","author":"S Greatorex","year":"2023","unstructured":"Greatorex S, Kaur S, Xirouchaki CE, Goh PK, Wiede F, Genders AJ, Tran M, Jia Y, Raajendiran A, Brown WA et al (2023) Mitochondria- and NOX4-dependent antioxidant defense mitigates progression to nonalcoholic steatohepatitis in obesity. J Clin Invest 134(3):e162533. https:\/\/doi.org\/10.1172\/JCI162533","journal-title":"J Clin Invest"},{"issue":"6","key":"11453_CR136","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1007\/s10735-023-10161-6","volume":"54","author":"N Zeng","year":"2023","unstructured":"Zeng N, Jian Z, Xu J, Zheng S, Fan Y, Xiao F (2023) DLK1 overexpression improves sepsis-induced cardiac dysfunction and fibrosis in mice through the TGF-\u03b21\/Smad3 signaling pathway and MMPs. J Mol Histol 54(6):655\u2013664. https:\/\/doi.org\/10.1007\/s10735-023-10161-6","journal-title":"J Mol Histol"},{"issue":"1","key":"11453_CR137","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/s0025-7125(03)00128-7","volume":"88","author":"JR Sowers","year":"2004","unstructured":"Sowers JR, Frohlich ED (2004) Insulin and insulin resistance: impact on blood pressure and cardiovascular disease. Med Clin North Am 88(1):63\u201382. https:\/\/doi.org\/10.1016\/s0025-7125(03)00128-7","journal-title":"Med Clin North Am"},{"issue":"5","key":"11453_CR138","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1111\/j.1751-553X.2012.01420.x","volume":"34","author":"AA Timur","year":"2012","unstructured":"Timur AA, Murugesan G, Zhang L, Aung PP, Barnard J, Wang QK, Gaussem P, Silverstein RL, Bhatt DL, Kottke-Marchant K (2012) P2RY1 and P2RY12 polymorphisms and on-aspirin platelet reactivity in patients with coronary artery disease. Int J Lab Hematol 34(5):473\u2013483. https:\/\/doi.org\/10.1111\/j.1751-553X.2012.01420.x","journal-title":"Int J Lab Hematol"},{"issue":"6","key":"11453_CR139","doi-asserted-by":"publisher","DOI":"10.23750\/abm.v92i6.9622","volume":"92","author":"E Khosravi","year":"2022","unstructured":"Khosravi E, Sadeghian L, Mohamadynejad P, Dianatkhah M, Hajizadeh M, Gharipour M (2022) Association study of polymorphism in Thrombomodulin gene [rs1042579] with cardiovascular disease. Acta Biomed 92(6):e2021282. https:\/\/doi.org\/10.23750\/abm.v92i6.9622","journal-title":"Acta Biomed"},{"issue":"2","key":"11453_CR140","doi-asserted-by":"publisher","DOI":"10.1093\/ehjopen\/oeaf028","volume":"5","author":"JA Lee","year":"2025","unstructured":"Lee JA, Wise J, Raudsepp SD, Paton LN, Powell J, Jina K, Aldous S, Troughton RW, Adamson PD, Richards AM et al (2025) Insulin-like growth factor binding protein-3 (IGFBP-3): a biomarker of coronary artery disease induced myocardial ischaemia. Eur Heart J Open 5(2):oeaf028. https:\/\/doi.org\/10.1093\/ehjopen\/oeaf028","journal-title":"Eur Heart J Open"},{"issue":"12","key":"11453_CR141","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9123952","volume":"9","author":"E Haj-Yehia","year":"2020","unstructured":"Haj-Yehia E, Mertens RW, Kahles F, R\u00fcckbeil MV, Rau M, Moellmann J, Biener M, Almalla M, Schroeder J, Giannitsis E et al (2020) Peptide YY (PYY) is associated with cardiovascular risk in patients with acute myocardial infarction. J Clin Med 9(12):3952. https:\/\/doi.org\/10.3390\/jcm9123952","journal-title":"J Clin Med"},{"issue":"18","key":"11453_CR142","doi-asserted-by":"publisher","first-page":"1389","DOI":"10.1089\/ars.2014.6221","volume":"23","author":"AE Vendrov","year":"2015","unstructured":"Vendrov AE, Vendrov KC, Smith A, Yuan J, Sumida A, Robidoux J, Runge MS, Madamanchi NR (2015) NOX4 NADPH oxidase-dependent mitochondrial oxidative stress in aging-associated cardiovascular disease. Antioxid Redox Signal 23(18):1389\u20131409. https:\/\/doi.org\/10.1089\/ars.2014.6221","journal-title":"Antioxid Redox Signal"},{"issue":"1","key":"11453_CR143","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201903131R","volume":"35","author":"L Marquez-Exposito","year":"2021","unstructured":"Marquez-Exposito L, Rodrigues-Diez RR, Rayego-Mateos S, Fierro-Fernandez M, Rodrigues-Diez R, Orejudo M, Santos-Sanchez L, Blanco EM, Laborda J, Mezzano S et al (2021) Deletion of delta-like 1 homologue accelerates renal inflammation by modulating the Th17 immune response. FASEB J 35(1):e21213. https:\/\/doi.org\/10.1096\/fj.201903131R","journal-title":"FASEB J"},{"issue":"3","key":"11453_CR144","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1007\/s00467-007-0611-2","volume":"23","author":"RH Mak","year":"2008","unstructured":"Mak RH (2008) Insulin and its role in chronic kidney disease. Pediatr Nephrol 23(3):355\u2013362. https:\/\/doi.org\/10.1007\/s00467-007-0611-2","journal-title":"Pediatr Nephrol"},{"issue":"9","key":"11453_CR145","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2024.109839","volume":"27","author":"H Ding","year":"2024","unstructured":"Ding H, Xu Z, Lu Y, Yuan Q, Li J, Sun Q (2024) Kidney fibrosis molecular mechanisms Spp1 influences fibroblast activity through transforming growth factor beta smad signaling. iScience 27(9):109839. https:\/\/doi.org\/10.1016\/j.isci.2024.109839","journal-title":"iScience"},{"issue":"5","key":"11453_CR146","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1530\/EJE-11-0923","volume":"166","author":"AK B\u00fcscher","year":"2012","unstructured":"B\u00fcscher AK, B\u00fcscher R, Pridzun L et al (2012) Functional and total IGFBP3 for the assessment of disorders of the GH\/IGF1 axis in children with chronic kidney disease, GH deficiency, or short stature after SGA status at birth. Eur J Endocrinol 166(5):923\u2013931. https:\/\/doi.org\/10.1530\/EJE-11-0923","journal-title":"Eur J Endocrinol"},{"issue":"8","key":"11453_CR147","doi-asserted-by":"publisher","first-page":"1306","DOI":"10.1093\/ndt\/gfz054","volume":"35","author":"AL Messchendorp","year":"2020","unstructured":"Messchendorp AL, Casteleijn NF, Meijer E, Gansevoort RT (2020) Somatostatin in renal physiology and autosomal dominant polycystic kidney disease. Nephrol Dial Transplant 35(8):1306\u20131316. https:\/\/doi.org\/10.1093\/ndt\/gfz054","journal-title":"Nephrol Dial Transplant"},{"issue":"11","key":"11453_CR148","doi-asserted-by":"publisher","first-page":"3696","DOI":"10.1093\/ndt\/gfn297","volume":"23","author":"M P\u00e9rez-Font\u00e1n","year":"2008","unstructured":"P\u00e9rez-Font\u00e1n M, Cordido F, Rodr\u00edguez-Carmona A, Pen\u00edn M, D\u00edaz-Cambre H, L\u00f3pez-Mu\u00f1iz A, Sangiao-Alvarellos S, Garc\u00eda-Buela J (2008) Short-term regulation of peptide YY secretion by a mixed meal or peritoneal glucose-based dialysate in patients with chronic renal failure. Nephrol Dial Transplant 23(11):3696\u20133703. https:\/\/doi.org\/10.1093\/ndt\/gfn297","journal-title":"Nephrol Dial Transplant"},{"issue":"1","key":"11453_CR149","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-025-03264-z","volume":"26","author":"Y Li","year":"2025","unstructured":"Li Y, Zhou C, Sun J, Wang E, Wang C, Liu X, Zhou X, Bai J (2025) Inhibition of DLK1 regulates AT2 differentiation and alleviates established pulmonary fibrosis by upregulating TTF-1\/CLDN6. Respir Res 26(1):188. https:\/\/doi.org\/10.1186\/s12931-025-03264-z","journal-title":"Respir Res"},{"key":"11453_CR150","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/627384","volume":"2013","author":"S Singh","year":"2013","unstructured":"Singh S, Prakash YS, Linneberg A, Agrawal A (2013) Insulin and the lung: connecting asthma and metabolic syndrome. J Allergy 2013:627384. https:\/\/doi.org\/10.1155\/2013\/627384","journal-title":"J Allergy"},{"issue":"2","key":"11453_CR151","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02441-2018","volume":"54","author":"C Morse","year":"2019","unstructured":"Morse C, Tabib T, Sembrat J, Buschur KL, Bittar HT, Valenzi E, Jiang Y, Kass DJ, Gibson K, Chen W et al (2019) Proliferating SPP1\/MERTK-expressing macrophages in idiopathic pulmonary fibrosis. Eur Respir J 54(2):1802441. https:\/\/doi.org\/10.1183\/13993003.02441-2018","journal-title":"Eur Respir J"},{"issue":"3","key":"11453_CR152","doi-asserted-by":"publisher","DOI":"10.5867\/medwave.2024.03.2783","volume":"24","author":"G de Carvalho","year":"2024","unstructured":"de Carvalho G, Sep\u00falveda-Loyola W, de Oliveira Lima L, Fernandes Szezerbaty SK, Poli-Frederico RC, Guti\u00e9rrez-Espinoza H, Valenzuela-Fuenzalida JJ, Probst VS (2024) Association of IGF-1 and IGF-2 genotypes with respiratory muscle strength in individuals with COPD: a cross-sectional study. Medwave 24(3):e2783. https:\/\/doi.org\/10.5867\/medwave.2024.03.2783","journal-title":"Medwave"},{"issue":"1","key":"11453_CR153","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1530\/EJE-11-0778","volume":"166","author":"AM Ahasic","year":"2012","unstructured":"Ahasic AM, Zhai R, Su L, Zhao Y, Aronis KN, Thompson BT, Mantzoros CS, Christiani DC (2012) IGF1 and IGFBP3 in acute respiratory distress syndrome. Eur J Endocrinol 166(1):121\u2013129. https:\/\/doi.org\/10.1530\/EJE-11-0778","journal-title":"Eur J Endocrinol"},{"issue":"2","key":"11453_CR154","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1016\/j.peptides.2012.02.011","volume":"34","author":"JO Ram\u00edrez-Jarqu\u00edn","year":"2012","unstructured":"Ram\u00edrez-Jarqu\u00edn JO, Lara-Hern\u00e1ndez S, L\u00f3pez-Guerrero JJ, Aguileta MA, Rivera-Angulo AJ, Sampieri A, Vaca L, Ordaz B, Pe\u00f1a-Ortega F (2012) Somatostatin modulates generation of inspiratory rhythms and determines asphyxia survival. Peptides 34(2):360\u2013372. https:\/\/doi.org\/10.1016\/j.peptides.2012.02.011","journal-title":"Peptides"},{"key":"11453_CR155","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.880878","volume":"13","author":"A Harijith","year":"2022","unstructured":"Harijith A, Basa P, Ha A, Thomas J, Jafri A, Fu P, MacFarlane PM, Raffay TM, Natarajan V, Sudhadevi T (2022) NOX4 mediates epithelial cell death in hyperoxic acute lung injury through mitochondrial reactive oxygen species. Front Pharmacol 13:880878. https:\/\/doi.org\/10.3389\/fphar.2022.880878","journal-title":"Front Pharmacol"},{"issue":"13","key":"11453_CR156","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23136897","volume":"23","author":"M Perram\u00f3n","year":"2022","unstructured":"Perram\u00f3n M, Jim\u00e9nez W (2022) Pituitary tumor-transforming gene 1\/Delta like non-canonical Notch ligand 1 signaling in chronic liver diseases. Int J Mol Sci 23(13):6897. https:\/\/doi.org\/10.3390\/ijms23136897","journal-title":"Int J Mol Sci"},{"issue":"1","key":"11453_CR157","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-66287-4","volume":"14","author":"X Wu","year":"2024","unstructured":"Wu X, Yuan C, Pan J, Zhou Y, Pan X, Kang J, Ren L, Gong L, Li Y (2024) CXCL9, IL2RB, and SPP1, potential diagnostic biomarkers in the co-morbidity pattern of atherosclerosis and non-alcoholic steatohepatitis. Sci Rep 14(1):16364. https:\/\/doi.org\/10.1038\/s41598-024-66287-4","journal-title":"Sci Rep"},{"issue":"2","key":"11453_CR158","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1038\/s41366-020-00687-0","volume":"45","author":"PJ Giraudi","year":"2021","unstructured":"Giraudi PJ, Giuricin M, Bonazza D, de Manzini N, Tiribelli C, Palmisano S, Rosso N (2021) Modifications of IGF2 and EGFR plasma protein concentrations in NAFLD patients after bariatric surgery. Int J Obes (Lond) 45(2):374\u2013382. https:\/\/doi.org\/10.1038\/s41366-020-00687-0","journal-title":"Int J Obes (Lond)"},{"issue":"12","key":"11453_CR159","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1515\/jpem-2015-0328","volume":"29","author":"X Kan","year":"2016","unstructured":"Kan X, Liu G, Yang Y, Yang Q, Li Y, Wang F (2016) Serum vascular endothelial cadherin and thrombomodulin are markers of non-alcoholic fatty liver disease in children. J Pediatr Endocrinol Metab 29(12):1331\u20131335. https:\/\/doi.org\/10.1515\/jpem-2015-0328","journal-title":"J Pediatr Endocrinol Metab"},{"issue":"6","key":"11453_CR160","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1007\/s12192-018-0929-7","volume":"23","author":"NM Aziz","year":"2018","unstructured":"Aziz NM, Ragy MM, Ahmed SM (2018) Somatostatin analogue, octreotide, improves restraint stress-induced liver injury by ameliorating oxidative stress, inflammatory response, and activation of hepatic stellate cells. Cell Stress Chaperones 23(6):1237\u20131245. https:\/\/doi.org\/10.1007\/s12192-018-0929-7","journal-title":"Cell Stress Chaperones"},{"issue":"2","key":"11453_CR161","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/S1665-2681(19)31788-0","volume":"8","author":"N Oruc","year":"2009","unstructured":"Oruc N, Ozutemiz O, Berdeli A, Ersoz G, Gunsar F, Karasu Z, Ilter T, Batur Y, Akarca US (2009) Common SPINK-1 mutations do not predispose to the development of non-alcoholic fatty liver disease. Ann Hepatol 8(2):116\u2013119","journal-title":"Ann Hepatol"},{"issue":"5","key":"11453_CR162","doi-asserted-by":"publisher","DOI":"10.3390\/genes12050680","volume":"12","author":"R Dai","year":"2021","unstructured":"Dai R, Wang Z, Ahmed SA (2021) Epigenetic contribution and genomic imprinting Dlk1-Dio3 miRNAs in systemic lupus erythematosus. Genes 12(5):680. https:\/\/doi.org\/10.3390\/genes12050680","journal-title":"Genes"},{"issue":"3","key":"11453_CR163","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204581","volume":"74","author":"S Gazal","year":"2015","unstructured":"Gazal S, Sacre K, Allanore Y, Teruel M, Goodall AH, Tohma S, Alfredsson L, Okada Y, Xie G, Constantin A et al (2015) Identification of secreted phosphoprotein 1 gene as a new rheumatoid arthritis susceptibility gene. Ann Rheum Dis 74(3):e19. https:\/\/doi.org\/10.1136\/annrheumdis-2013-204581","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"11453_CR164","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1530\/EJE-14-1078","volume":"173","author":"A Peet","year":"2015","unstructured":"Peet A, H\u00e4m\u00e4l\u00e4inen AM, Kool P, Ilonen J, Knip M, Tillmann V, DIABIMMUNE Study Group (2015) Circulating IGF1 and IGFBP3 in relation to the development of \u03b2-cell autoimmunity in young children. Eur J Endocrinol 173(2):129\u2013137. https:\/\/doi.org\/10.1530\/EJE-14-1078","journal-title":"Eur J Endocrinol"},{"key":"11453_CR165","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/5523582","volume":"2021","author":"JA Balog","year":"2021","unstructured":"Balog JA, Kemeny A, Puskas LG, Burcsar S, Balog A, Szebeni GJ (2021) Investigation of newly diagnosed drug-naive patients with systemic autoimmune diseases revealed the cleaved peptide tyrosine tyrosine (PYY 3-36) as a specific plasma biomarker of rheumatoid arthritis. Mediators Inflamm 2021:5523582. https:\/\/doi.org\/10.1155\/2021\/5523582","journal-title":"Mediators Inflamm"},{"key":"11453_CR166","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/j.bone.2018.02.030","volume":"110","author":"F Figeac","year":"2018","unstructured":"Figeac F, Andersen DC, Nipper Nielsen CA, Ditzel N, Sheikh SP, Skj\u00f8dt K, Kassem M, Jensen CH, Abdallah BM (2018) Antibody-based inhibition of circulating DLK1 protects from estrogen deficiency-induced bone loss in mice. Bone 110:312\u2013320. https:\/\/doi.org\/10.1016\/j.bone.2018.02.030","journal-title":"Bone"},{"issue":"5","key":"11453_CR167","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0097428","volume":"9","author":"JH Chen","year":"2014","unstructured":"Chen JH, Chen YC, Mao CL, Chiou JM, Tsao CK, Tsai KS (2014) Association between secreted phosphoprotein-1 (SPP1) polymorphisms and low bone mineral density in women. PLoS ONE 9(5):e97428. https:\/\/doi.org\/10.1371\/journal.pone.0097428","journal-title":"PLoS ONE"},{"issue":"1","key":"11453_CR168","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1007\/s00011-025-02096-3","volume":"74","author":"C Zhao","year":"2025","unstructured":"Zhao C, Li Q, Jin P, Shen C (2025) Tuberculosis-infected macrophage exosomal miR-125b-5p induces osteoporosis by targeting IGF2 through the PI3K\/AKT pathway. Inflamm Res 74(1):126. https:\/\/doi.org\/10.1007\/s00011-025-02096-3","journal-title":"Inflamm Res"},{"key":"11453_CR169","doi-asserted-by":"publisher","DOI":"10.1155\/2023\/2613766","volume":"2023","author":"X Shi","year":"2023","unstructured":"Shi X, Jiang J, Hong R, Xu F, Dai S (2023) Circulating IGFBP-3 and interleukin 6 as predictors of osteoporosis in postmenopausal women: a cross-sectional study. Mediat Inflamm 2023:2613766. https:\/\/doi.org\/10.1155\/2023\/2613766","journal-title":"Mediat Inflamm"},{"key":"11453_CR170","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/8164064","volume":"2020","author":"Y Chen","year":"2020","unstructured":"Chen Y, Bai R, Chen W, Li S, Jiang Y (2020) Zhuang-Gu-Fang treats osteoporosis in ovariectomized rats by increasing the osteogenesis-related factors leptin, ghrelin, and PYY. Evid Based Complement Alternat Med 2020:8164064. https:\/\/doi.org\/10.1155\/2020\/8164064","journal-title":"Evid Based Complement Alternat Med"},{"key":"11453_CR171","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.freeradbiomed.2023.01.026","volume":"198","author":"H Zhang","year":"2023","unstructured":"Zhang H, Wang A, Li G, Zhai Q, Huang Z, Wang X, Cao Z, Liu L, Liu G, Chen B et al (2023) Osteoporotic bone loss from excess iron accumulation is driven by NOX4-triggered ferroptosis in osteoblasts. Free Radic Biol Med 198:123\u2013136. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2023.01.026","journal-title":"Free Radic Biol Med"},{"issue":"23","key":"11453_CR172","doi-asserted-by":"publisher","first-page":"3915","DOI":"10.1042\/BCJ20170323","volume":"474","author":"R Dubey","year":"2017","unstructured":"Dubey R, Minj P, Malik N, Sardesai DM, Kulkarni SH, Acharya JD, Bhavesh NS, Sharma S, Kumar A (2017) Recombinant human islet amyloid polypeptide forms shorter fibrils and mediates \u03b2-cell apoptosis via generation of oxidative stress. Biochem J 474(23):3915\u20133934. https:\/\/doi.org\/10.1042\/BCJ20170323","journal-title":"Biochem J"},{"issue":"2","key":"11453_CR173","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0088052","volume":"9","author":"B Yang","year":"2014","unstructured":"Yang B, Wagner J, Damaschke N, Yao T, Wuerzberger-Davis SM, Lee MH, Svaren J, Miyamoto S, Jarrard DF (2014) A novel pathway links oxidative stress to loss of insulin growth factor-2 (IGF2) imprinting through NF-\u03baB activation. PLoS ONE 9(2):e88052. https:\/\/doi.org\/10.1371\/journal.pone.0088052","journal-title":"PLoS ONE"},{"key":"11453_CR174","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/6831779","volume":"2022","author":"D Hu","year":"2022","unstructured":"Hu D, Ge Y, Cui Y, Li K, Chen J, Zhang C, Liu Q, He L, Chen W, Chen J et al (2022) Upregulated IGFBP3 with aging is involved in modulating apoptosis, oxidative stress, and fibrosis: a target of age-related erectile dysfunction. Oxid Med Cell Longev 2022:6831779. https:\/\/doi.org\/10.1155\/2022\/6831779","journal-title":"Oxid Med Cell Longev"},{"key":"11453_CR175","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2022.112064","volume":"172","author":"AA Syed","year":"2023","unstructured":"Syed AA, Reza MI, Yadav H, Gayen JR (2023) Hesperidin inhibits NOX4 mediated oxidative stress and inflammation by upregulating SIRT1 in experimental diabetic neuropathy. Exp Gerontol 172:112064. https:\/\/doi.org\/10.1016\/j.exger.2022.112064","journal-title":"Exp Gerontol"},{"issue":"6","key":"11453_CR176","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1007\/s00702-013-1147-1","volume":"121","author":"M Ramalingam","year":"2014","unstructured":"Ramalingam M, Kim SJ (2014) Mechanisms of action of brain insulin against neurodegenerative diseases. J Neural Transm (Vienna) 121(6):611\u2013626. https:\/\/doi.org\/10.1007\/s00702-013-1147-1","journal-title":"J Neural Transm (Vienna)"},{"issue":"3","key":"11453_CR177","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1038\/s41593-023-01257-z","volume":"26","author":"S De Schepper","year":"2023","unstructured":"De Schepper S, Ge JZ, Crowley G, Ferreira LSS, Garceau D, Toomey CE, Sokolova D, Rueda-Carrasco J, Shin SH, Kim JS et al (2023) Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer\u2019s disease. Nat Neurosci 26(3):406\u2013415. https:\/\/doi.org\/10.1038\/s41593-023-01257-z","journal-title":"Nat Neurosci"},{"issue":"6","key":"11453_CR178","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1016\/j.tins.2023.03.007","volume":"46","author":"CM Alberini","year":"2023","unstructured":"Alberini CM (2023) IGF2 in memory, neurodevelopmental disorders, and neurodegenerative diseases. Trends Neurosci 46(6):488\u2013502. https:\/\/doi.org\/10.1016\/j.tins.2023.03.007","journal-title":"Trends Neurosci"},{"issue":"9","key":"11453_CR179","doi-asserted-by":"publisher","first-page":"1729","DOI":"10.1016\/j.psyneuen.2013.02.006","volume":"38","author":"P Johansson","year":"2013","unstructured":"Johansson P, \u00c5berg D, Johansson JO, Mattsson N, Hansson O, Ahr\u00e9n B, Isgaard J, \u00c5berg ND, Blennow K, Zetterberg H et al (2013) Serum but not cerebrospinal fluid levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 (IGFBP-3) are increased in Alzheimer\u2019s disease. Psychoneuroendocrinology 38(9):1729\u20131737. https:\/\/doi.org\/10.1016\/j.psyneuen.2013.02.006","journal-title":"Psychoneuroendocrinology"},{"issue":"9","key":"11453_CR180","doi-asserted-by":"publisher","first-page":"1961","DOI":"10.4103\/1673-5374.390973","volume":"19","author":"N Boonpraman","year":"2024","unstructured":"Boonpraman N, Yi SS (2024) NADPH oxidase 4 (NOX4) as a biomarker and therapeutic target in neurodegenerative diseases. Neural Regen Res 19(9):1961\u20131966. https:\/\/doi.org\/10.4103\/1673-5374.390973","journal-title":"Neural Regen Res"},{"issue":"2","key":"11453_CR181","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1210\/jc.2006-1819","volume":"92","author":"PA Sarafidis","year":"2007","unstructured":"Sarafidis PA, Bakris GL (2007) Review: insulin and endothelin: an interplay contributing to hypertension development? J Clin Endocrinol Metab 92(2):379\u2013385. https:\/\/doi.org\/10.1210\/jc.2006-1819","journal-title":"J Clin Endocrinol Metab"},{"key":"11453_CR182","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2023.115816","volume":"168","author":"YX Chen","year":"2023","unstructured":"Chen YX, Deng ZH, Xue-Gao Q-D, Juan-Yin CGH, Li JG, Zhao YM, Zhang HT et al (2023) Exosomes derived from mesenchymal stromal cells exert a therapeutic effect on hypoxia-induced pulmonary hypertension by modulating the YAP1\/SPP1 signaling pathway. Biomed Pharmacother 168:115816. https:\/\/doi.org\/10.1016\/j.biopha.2023.115816","journal-title":"Biomed Pharmacother"},{"issue":"1","key":"11453_CR183","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-021-05598-5","volume":"14","author":"ABL Neto","year":"2021","unstructured":"Neto ABL, Vasconcelos NBR, Dos Santos TR, Duarte LEC, Assun\u00e7\u00e3o ML, de Sales-Marques C, Ferreira HDS (2021) Prevalence of IGFBP3, NOS3 and TCF7L2 polymorphisms and their association with hypertension: a population-based study with Brazilian women of African descent. BMC Res Notes 14(1):186. https:\/\/doi.org\/10.1186\/s13104-021-05598-5","journal-title":"BMC Res Notes"},{"issue":"6","key":"11453_CR184","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1097\/SLA.0000000000003062","volume":"269","author":"RI Troisi","year":"2019","unstructured":"Troisi RI, Vanlander A, Giglio MC, Van Limmen J, Scudeller L, Heyse B, De Baerdemaeker L, Croo A, Voet D, Praet M et al (2019) Somatostatin as inflow modulator in liver-transplant recipients with severe portal hypertension: a randomized trial. Ann Surg 269(6):1025\u20131033. https:\/\/doi.org\/10.1097\/SLA.0000000000003062","journal-title":"Ann Surg"},{"issue":"9","key":"11453_CR185","doi-asserted-by":"publisher","first-page":"H1528","DOI":"10.1152\/ajpheart.00070.2015","volume":"309","author":"X Zhu","year":"2015","unstructured":"Zhu X, Gillespie DG, Jackson EK (2015) NPY1-36 and PYY1-36 activate cardiac fibroblasts: an effect enhanced by genetic hypertension and inhibition of dipeptidyl peptidase 4. Am J Physiol Heart Circ Physiol 309(9):H1528\u2013H1542. https:\/\/doi.org\/10.1152\/ajpheart.00070.2015","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"10","key":"11453_CR186","doi-asserted-by":"publisher","first-page":"13396","DOI":"10.1096\/fj.202000966RR","volume":"34","author":"TS Pavlov","year":"2020","unstructured":"Pavlov TS, Palygin O, Isaeva E, Levchenko V, Khedr S, Blass G, Ilatovskaya DV, Cowley AW Jr, Staruschenko A (2020) NOX4-dependent regulation of ENaC in hypertension and diabetic kidney disease. FASEB J 34(10):13396\u201313408. https:\/\/doi.org\/10.1096\/fj.202000966RR","journal-title":"FASEB J"},{"issue":"13","key":"11453_CR187","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25136995","volume":"25","author":"R Rejas-Gonz\u00e1lez","year":"2024","unstructured":"Rejas-Gonz\u00e1lez R, Montero-Calle A, Valverde A, Salvador NP, Carball\u00e9s MJC, Aus\u00edn-Gonz\u00e1lez E, S\u00e1nchez-Naves J, Campuzano S, Barderas R, Guzman-Aranguez A (2024) Proteomics analyses of small extracellular vesicles of aqueous humor: identification and validation of GAS6 and SPP1 as glaucoma markers. Int J Mol Sci 25(13):6995. https:\/\/doi.org\/10.3390\/ijms25136995","journal-title":"Int J Mol Sci"},{"key":"11453_CR188","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/986217","volume":"2013","author":"D Romaniuk","year":"2013","unstructured":"Romaniuk D, Kimsa MW, Strzalka-Mrozik B, Kimsa MC, Kabiesz A, Romaniuk W, Mazurek U (2013) Gene expression of IGF1, IGF1R, and IGFBP3 in epiretinal membranes of patients with proliferative diabetic retinopathy: preliminary study. Mediators Inflamm 2013:986217. https:\/\/doi.org\/10.1155\/2013\/986217","journal-title":"Mediators Inflamm"},{"issue":"4","key":"11453_CR189","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1111\/ijs.12225","volume":"9","author":"G Ntaios","year":"2014","unstructured":"Ntaios G, Papavasileiou V, Bargiota A, Makaritsis K, Michel P (2014) Intravenous insulin treatment in acute stroke: a systematic review and meta-analysis of randomized controlled trials. Int J Stroke 9(4):489\u2013493. https:\/\/doi.org\/10.1111\/ijs.12225","journal-title":"Int J Stroke"},{"issue":"1","key":"11453_CR190","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-025-04663-2","volume":"25","author":"S Fei","year":"2025","unstructured":"Fei S, Xu M, Liu Z, Xie H, Yu Y, Chu Y, Zhu L, Fang Z, Jin Y, Yao Y et al (2025) Molecular epidemiological study of exosomes circZNF609, circPUM1, IGF2 with ischemic stroke. BMC Cardiovasc Disord 25(1):215. https:\/\/doi.org\/10.1186\/s12872-025-04663-2","journal-title":"BMC Cardiovasc Disord"},{"issue":"12","key":"11453_CR191","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18122678","volume":"18","author":"PK Janicki","year":"2017","unstructured":"Janicki PK, Eyileten C, Ruiz-Velasco V, Sedeek KA, Pordzik J, Czlonkowska A, Kurkowska-Jastrzebska I, Sugino S, Imamura-Kawasawa Y, Mirowska-Guzel D et al (2017) Population-specific associations of deleterious rare variants in coding region of P2RY1-P2RY12 purinergic receptor genes in large-vessel ischemic stroke patients. Int J Mol Sci 18(12):2678. https:\/\/doi.org\/10.3390\/ijms18122678","journal-title":"Int J Mol Sci"},{"issue":"9","key":"11453_CR192","doi-asserted-by":"publisher","first-page":"e916","DOI":"10.1212\/WNL.0000000000200783","volume":"99","author":"Z Zhu","year":"2022","unstructured":"Zhu Z, Guo D, Jia Y, Zhang K, Shi M, Peng Y, Yang P, Chen J, Zhang J, Wang A et al (2022) Plasma thrombomodulin levels and ischemic stroke: a population-based prognostic cohort study. Neurology 99(9):e916\u2013e924. https:\/\/doi.org\/10.1212\/WNL.0000000000200783","journal-title":"Neurology"},{"issue":"7","key":"11453_CR193","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1055\/s-0043-103965","volume":"125","author":"M Armbrust","year":"2017","unstructured":"Armbrust M, Worthmann H, Dengler R, Schumacher H, Lichtinghagen R, Eschenfelder CC, Endres M, Ebinger M (2017) Circulating insulin-like growth factor-1 and insulin-like growth factor binding protein-3 predict three-months outcome after ischemic stroke. Exp Clin Endocrinol Diabetes 125(7):485\u2013491. https:\/\/doi.org\/10.1055\/s-0043-103965","journal-title":"Exp Clin Endocrinol Diabetes"},{"issue":"3","key":"11453_CR194","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1007\/s10571-020-00874-7","volume":"41","author":"F Chiazza","year":"2021","unstructured":"Chiazza F, Pintana H, Lietzau G, Nystr\u00f6m T, Patrone C, Darsalia V (2021) The stroke-induced increase of somatostatin-expressing neurons is inhibited by diabetes: a potential mechanism at the basis of impaired stroke recovery. Cell Mol Neurobiol 41(3):591\u2013603. https:\/\/doi.org\/10.1007\/s10571-020-00874-7","journal-title":"Cell Mol Neurobiol"},{"key":"11453_CR195","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/1148874","volume":"2022","author":"G Li","year":"2022","unstructured":"Li G, Ye C, Zhu Y, Zhang T, Gu J, Pan J, Wang F, Wu F, Huang K, Xu K et al (2022) Oxidative injury in ischemic stroke: a focus on NADPH oxidase 4. Oxid Med Cell Longev 2022:1148874. https:\/\/doi.org\/10.1155\/2022\/1148874","journal-title":"Oxid Med Cell Longev"},{"key":"11453_CR196","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2023.110645","volume":"205","author":"M Dolatshahi","year":"2023","unstructured":"Dolatshahi M, Sanjari Moghaddam H, Saberi P, Mohammadi S, Aarabi MH (2023) Central nervous system microstructural alterations in type 1 diabetes mellitus: a systematic review of diffusion tensor imaging studies. Diabetes Res Clin Pract 205:110645. https:\/\/doi.org\/10.1016\/j.diabres.2023.110645","journal-title":"Diabetes Res Clin Pract"},{"issue":"6","key":"11453_CR197","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1097\/00000441-200212000-00004","volume":"324","author":"A Magrini","year":"2002","unstructured":"Magrini A, Bottini N, Nicotra M, Cosmi E, Bottini E, Bergamaschi A (2002) Smoking and the genetics of signal transduction: an association study on retinopathy in type 1 diabetes. Am J Med Sci 324(6):310\u2013313. https:\/\/doi.org\/10.1097\/00000441-200212000-00004","journal-title":"Am J Med Sci"},{"issue":"1","key":"11453_CR198","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1161\/HYPERTENSIONAHA.112.192500","volume":"60","author":"M Gal\u00e1n","year":"2012","unstructured":"Gal\u00e1n M, Kassan M, Choi SK, Partyka M, Trebak M, Henrion D, Matrougui K (2012) A novel role for epidermal growth factor receptor tyrosine kinase and its downstream endoplasmic reticulum stress in cardiac damage and microvascular dysfunction in type 1 diabetes mellitus. Hypertension 60(1):71\u201380. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.112.192500","journal-title":"Hypertension"},{"key":"11453_CR199","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.884549","volume":"13","author":"X Pan","year":"2022","unstructured":"Pan X, Tao S, Tong N (2022) Potential therapeutic targeting neurotransmitter receptors in diabetes. Front Endocrinol (Lausanne) 13:884549. https:\/\/doi.org\/10.3389\/fendo.2022.884549","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"12","key":"11453_CR200","doi-asserted-by":"publisher","first-page":"6006","DOI":"10.1210\/en.2008-0274","volume":"149","author":"AT Suckow","year":"2008","unstructured":"Suckow AT, Comoletti D, Waldrop MA, Mosedale M, Egodage S, Taylor P, Chessler SD (2008) Expression of neurexin, neuroligin, and their cytoplasmic binding partners in the pancreatic beta-cells and the involvement of neuroligin in insulin secretion. Endocrinology 149(12):6006\u20136017. https:\/\/doi.org\/10.1210\/en.2008-0274","journal-title":"Endocrinology"},{"issue":"3","key":"11453_CR201","doi-asserted-by":"publisher","first-page":"R358","DOI":"10.1152\/ajpregu.00109.2020","volume":"319","author":"AK Grotle","year":"2020","unstructured":"Grotle AK, Huo Y, Harrison ML, Lee J, Ybarbo KM, Stone AJ (2020) Effects of type 1 diabetes on reflexive cardiovascular responses to intermittent muscle contraction. Am J Physiol Regul Integr Comp Physiol 319(3):R358\u2013R365. https:\/\/doi.org\/10.1152\/ajpregu.00109.2020","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"4","key":"11453_CR202","doi-asserted-by":"publisher","DOI":"10.3390\/biom15040505","volume":"15","author":"L Nigi","year":"2025","unstructured":"Nigi L, Pedace E, Dotta F, Sebastiani G (2025) Neutrophils in type 1 diabetes: untangling the intricate web of pathways and hypothesis. Biomolecules 15(4):505. https:\/\/doi.org\/10.3390\/biom15040505","journal-title":"Biomolecules"},{"issue":"11","key":"11453_CR203","doi-asserted-by":"publisher","DOI":"10.1007\/s11892-017-0930-z","volume":"17","author":"JC Needell","year":"2017","unstructured":"Needell JC, Zipris D (2017) Targeting innate immunity for type 1 diabetes prevention. Curr Diab Rep 17(11):113. https:\/\/doi.org\/10.1007\/s11892-017-0930-z","journal-title":"Curr Diab Rep"},{"issue":"1","key":"11453_CR204","doi-asserted-by":"publisher","first-page":"13","DOI":"10.5603\/EP.2017.0003","volume":"68","author":"M \u015anit","year":"2017","unstructured":"\u015anit M, Nabrdalik K, D\u0142ugaszek M, Gumprecht J, Trautsolt W, G\u00f3rczy\u0144ska-Kosiorz S, Grzeszczak W (2017) Association of rs 3807337 polymorphism of CALD1 gene with diabetic nephropathy occurrence in type 1 diabetes - preliminary results of a family-based study. Endokrynol Pol 68(1):13\u201317. https:\/\/doi.org\/10.5603\/EP.2017.0003","journal-title":"Endokrynol Pol"},{"issue":"12","key":"11453_CR205","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1002\/iub.1096","volume":"64","author":"R Pullakhandam","year":"2012","unstructured":"Pullakhandam R, Palika R, Ghosh S, Reddy GB (2012) Contrasting effects of type 2 and type 1 diabetes on plasma RBP4 levels: the significance of transthyretin. IUBMB Life 64(12):975\u2013982. https:\/\/doi.org\/10.1002\/iub.1096","journal-title":"IUBMB Life"},{"key":"11453_CR206","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexmp.2020.104432","volume":"114","author":"H Ding","year":"2020","unstructured":"Ding H, Wang F, Shi X, Ma H, Du Y, Hou L, Xing N (2020) LncRNA MALAT1 induces the dysfunction of \u03b2 cells via reducing the histone acetylation of the PDX-1 promoter in type 1 diabetes. Exp Mol Pathol 114:104432. https:\/\/doi.org\/10.1016\/j.yexmp.2020.104432","journal-title":"Exp Mol Pathol"},{"issue":"5","key":"11453_CR207","doi-asserted-by":"publisher","first-page":"3345","DOI":"10.1111\/jcmm.14225","volume":"23","author":"H Ao","year":"2019","unstructured":"Ao H, Liu B, Li H, Lu L (2019) Egr1 mediates retinal vascular dysfunction in diabetes mellitus via promoting p53 transcription. J Cell Mol Med 23(5):3345\u20133356. https:\/\/doi.org\/10.1111\/jcmm.14225","journal-title":"J Cell Mol Med"},{"issue":"1","key":"11453_CR208","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-023-04026-5","volume":"21","author":"N Noren Hooten","year":"2023","unstructured":"Noren Hooten N, Mode NA, Kowalik E, Omoniyi V, Zonderman AB, Ezike N, DiNubile MJ, Levinson SL, Evans MK (2023) Plasma gelsolin levels are associated with diabetes, sex, race, and poverty. J Transl Med 21(1):190. https:\/\/doi.org\/10.1186\/s12967-023-04026-5","journal-title":"J Transl Med"},{"issue":"8","key":"11453_CR209","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1111\/pedi.12222","volume":"16","author":"H Sk\u00e4rstrand","year":"2015","unstructured":"Sk\u00e4rstrand H, Vaziri-Sani F, Delli AJ, T\u00f6rn C, Elding Larsson H, Ivarsson S, Agardh D, Lernmark \u00c5, Sk\u00e5ne study group (2015) Neuropeptide Y is a minor autoantigen in newly diagnosed type 1 diabetes patients. Pediatr Diabetes 16(8):621\u2013628. https:\/\/doi.org\/10.1111\/pedi.12222","journal-title":"Pediatr Diabetes"},{"issue":"2","key":"11453_CR210","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1111\/andr.13119","volume":"10","author":"K Liu","year":"2022","unstructured":"Liu K, Sun T, Luan Y, Chen Y, Song J, Ling L, Yuan P, Li R, Cui K, Ruan Y et al (2022) Berberine ameliorates erectile dysfunction in rats with streptozotocin-induced diabetes mellitus through the attenuation of apoptosis by inhibiting the SPHK1\/S1P\/S1PR2 and MAPK pathways. Andrology 10(2):404\u2013418. https:\/\/doi.org\/10.1111\/andr.13119","journal-title":"Andrology"},{"issue":"1","key":"11453_CR211","doi-asserted-by":"publisher","first-page":"6176","DOI":"10.1038\/s41598-024-82214-z","volume":"15","author":"AM Abas","year":"2025","unstructured":"Abas AM, Esawy MM, Kamel F, Ali M (2025) Predictive roles of Asprosin and Gremlin-1 expression in Egyptian pediatric patients with type 1 diabetes. Sci Rep 15(1):6176. https:\/\/doi.org\/10.1038\/s41598-024-82214-z","journal-title":"Sci Rep"},{"issue":"1","key":"11453_CR212","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1515\/hmbci-2015-0036","volume":"26","author":"A Alkharusi","year":"2016","unstructured":"Alkharusi A, Mirecki-Garrido M, Ma Z, Zadjali F, Flores-Morales A, Nystr\u00f6m T, Castrillo A, Bjorklund A, Norstedt G, Fernandez-P\u00e9rez L (2016) Suppressor of cytokine signaling 2 (SOCS2) deletion protects against multiple low dose streptozotocin-induced type 1 diabetes in adult male mice. Horm Mol Biol Clin Investig 26(1):67\u201376. https:\/\/doi.org\/10.1515\/hmbci-2015-0036","journal-title":"Horm Mol Biol Clin Investig"},{"issue":"9","key":"11453_CR213","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1016\/j.clinbiochem.2009.01.012","volume":"42","author":"V Boraska","year":"2009","unstructured":"Boraska V, Torlak V, Skrabi\u0107 V, Kaci\u0107 Z, Jaksi\u0107 J, Stipanci\u0107 G, Uroi\u0107 AS, Markoti\u0107 A, Zemunik T (2009) Glycosyltransferase B4GALNT1 and type 1 diabetes in Croatian population: clinical investigation. Clin Biochem 42(9):819\u2013822. https:\/\/doi.org\/10.1016\/j.clinbiochem.2009.01.012","journal-title":"Clin Biochem"},{"issue":"3","key":"11453_CR214","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1093\/nutrit\/nuad056","volume":"82","author":"G Lu","year":"2024","unstructured":"Lu G, Li J, Gao T, Liu Q, Chen O, Zhang X, Xiao M, Guo Y, Wang J et al (2024) Integration of dietary nutrition and TRIB3 action into diabetes mellitus. Nutr Rev 82(3):361\u2013373. https:\/\/doi.org\/10.1093\/nutrit\/nuad056","journal-title":"Nutr Rev"},{"issue":"3","key":"11453_CR215","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1530\/JOE-14-0509","volume":"223","author":"C Zeng","year":"2014","unstructured":"Zeng C, Yi X, Zipris D, Liu H, Zhang L, Zheng Q, Malathi K, Jin G, Zhou A (2014) Rnase L contributes to experimentally induced type 1 diabetes onset in mice. J Endocrinol 223(3):277\u2013287. https:\/\/doi.org\/10.1530\/JOE-14-0509","journal-title":"J Endocrinol"},{"key":"11453_CR216","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1110337","volume":"14","author":"D Huo","year":"2023","unstructured":"Huo D, Liu YY, Zhang C, Zeng LT, Fan GQ, Zhang LQ, Pang J, Wang Y, Shen T, Li XF et al (2023) Serum glycoprotein non-metastatic melanoma protein B (GPNMB) level as a potential biomarker for diabetes mellitus-related cataract: a cross-sectional study. Front Endocrinol (Lausanne) 14:1110337. https:\/\/doi.org\/10.3389\/fendo.2023.1110337","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"4","key":"11453_CR217","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1097\/FPC.0b013e3282f70481","volume":"18","author":"BJ Schouwenberg","year":"2008","unstructured":"Schouwenberg BJ, Veldman BA, Spiering W, Coenen MJ, Franke B, Tack CJ, de Galan BE, Smits P (2008) The Arg16Gly variant of the \u03b22-adrenergic receptor predisposes to hypoglycemia unawareness in type 1 diabetes mellitus. Pharmacogenet Genomics 18(4):369\u2013372. https:\/\/doi.org\/10.1097\/FPC.0b013e3282f70481","journal-title":"Pharmacogenet Genomics"},{"issue":"5","key":"11453_CR218","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/j.jdiacomp.2012.05.012","volume":"26","author":"T Gu","year":"2012","unstructured":"Gu T, Horov\u00e1 E, M\u00f6llsten A, Seman NA, Falhammar H, Pr\u00e1zn\u00fd M, Brismar K, Gu HF (2012) GF2BP2 and IGF2 genetic effects in diabetes and diabetic nephropathy. J Diabetes Complicat 26(5):393\u2013398. https:\/\/doi.org\/10.1016\/j.jdiacomp.2012.05.012","journal-title":"J Diabetes Complicat"},{"key":"11453_CR219","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1131437","volume":"14","author":"C Cao","year":"2023","unstructured":"Cao C, Fu X, Wang X (2023) Case report: a novel mutation in TNFAIP3 in a patient with type 1 diabetes mellitus and haploinsufficiency of A20. Front Endocrinol (Lausanne) 14:1131437. https:\/\/doi.org\/10.3389\/fendo.2023.1131437","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"17","key":"11453_CR220","doi-asserted-by":"publisher","first-page":"11818","DOI":"10.1021\/acs.jmedchem.2c00926","volume":"65","author":"Y Wu","year":"2022","unstructured":"Wu Y, Qi Z, Wang B, Wang J, Liu Q, Wang A, Shi C, Zhou B, Liang Q, Wang W et al (2022) Discovery of IHMT-MST1-58 as a novel, potent, and selective MST1 inhibitor for the treatment of type 1\/2 diabetes. J Med Chem 65(17):11818\u201311839. https:\/\/doi.org\/10.1021\/acs.jmedchem.2c00926","journal-title":"J Med Chem"},{"issue":"3","key":"11453_CR221","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1073\/pnas.1524200113","volume":"113","author":"M Zhang","year":"2016","unstructured":"Zhang M, Lin Q, Qi T, Wang T, Chen CC, Riggs AD, Zeng D (2016) Growth factors and medium hyperglycemia induce Sox9+ ductal cell differentiation into \u03b2 cells in mice with reversal of diabetes. Proc Natl Acad Sci U S A 113(3):650\u2013655. https:\/\/doi.org\/10.1073\/pnas.1524200113","journal-title":"Proc Natl Acad Sci U S A"},{"key":"11453_CR222","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.atherosclerosis.2018.11.020","volume":"280","author":"D Bojanin","year":"2019","unstructured":"Bojanin D, Vekic J, Milenkovic T, Vukovic R, Zeljkovic A, Stefanovic A, Janac J, Ivanisevic J, Mitrovic K, Miljkovic M et al (2019) Association between proprotein convertase subtilisin\/kexin 9 (PCSK9) and lipoprotein subclasses in children with type 1 diabetes mellitus: effects of glycemic control. Atherosclerosis 280:14\u201320. https:\/\/doi.org\/10.1016\/j.atherosclerosis.2018.11.020","journal-title":"Atherosclerosis"},{"issue":"1","key":"11453_CR223","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-45738-4","volume":"13","author":"A Raugh","year":"2023","unstructured":"Raugh A, Jing Y, Bettini ML, Bettini M (2023) The amphiregulin\/EGFR axis has limited contribution in controlling autoimmune diabetes. Sci Rep 13(1):18653. https:\/\/doi.org\/10.1038\/s41598-023-45738-4","journal-title":"Sci Rep"},{"issue":"3","key":"11453_CR224","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1530\/JME-14-0065","volume":"53","author":"G Shi","year":"2014","unstructured":"Shi G, Sun C, Gu W, Yang M, Zhang X, Zhai N, Lu Y, Zhang Z, Shou P, Zhang Z et al (2014) Free fatty acid receptor 2, a candidate target for type 1 diabetes, induces cell apoptosis through ERK signaling. J Mol Endocrinol 53(3):367\u2013380. https:\/\/doi.org\/10.1530\/JME-14-0065","journal-title":"J Mol Endocrinol"},{"issue":"3","key":"11453_CR225","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1007\/s00592-012-0389-y","volume":"50","author":"S Sanda","year":"2013","unstructured":"Sanda S, Wei S, Rue T, Shilling H, Greenbaum C (2013) A SNP in G6PC2 predicts insulin secretion in type 1 diabetes. Acta Diabetol 50(3):459\u2013462. https:\/\/doi.org\/10.1007\/s00592-012-0389-y","journal-title":"Acta Diabetol"},{"issue":"11","key":"11453_CR226","doi-asserted-by":"publisher","first-page":"1635","DOI":"10.2967\/jnumed.118.224881","volume":"60","author":"E Khera","year":"2019","unstructured":"Khera E, Zhang L, Roberts S, Nessler I, Sandoval D, Reiner T, Thurber GM (2019) Blocking of glucagonlike peptide-1 receptors in the exocrine pancreas improves specificity for \u03b2-cells in a mouse model of type 1 diabetes. J Nucl Med 60(11):1635\u20131641. https:\/\/doi.org\/10.2967\/jnumed.118.224881","journal-title":"J Nucl Med"},{"issue":"9\u201310","key":"11453_CR227","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1242\/dmm.003210","volume":"3","author":"A Villasenor","year":"2010","unstructured":"Villasenor A, Wang ZV, Rivera LB, Ocal O, Asterholm IW, Scherer PE, Brekken RA, Cleaver O, Wilkie TM (2010) Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes. Dis Model Mech 3(9\u201310):567\u2013580. https:\/\/doi.org\/10.1242\/dmm.003210","journal-title":"Dis Model Mech"},{"issue":"2","key":"11453_CR228","doi-asserted-by":"publisher","first-page":"391","DOI":"10.2337\/db10-0426","volume":"60","author":"Y Lee","year":"2011","unstructured":"Lee Y, Wang MY, Du XQ, Charron MJ, Unger RH (2011) Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice. Diabetes 60(2):391\u2013397. https:\/\/doi.org\/10.2337\/db10-0426","journal-title":"Diabetes"},{"issue":"1","key":"11453_CR229","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-29211-1","volume":"8","author":"N Sandholm","year":"2018","unstructured":"Sandholm N, Haukka JK, Toppila I, Valo E, Harjutsalo V, Forsblom C, Groop PH (2018) Confirmation of GLRA3 as a susceptibility locus for albuminuria in Finnish patients with type 1 diabetes. Sci Rep 8(1):12408. https:\/\/doi.org\/10.1038\/s41598-018-29211-1","journal-title":"Sci Rep"},{"issue":"5","key":"11453_CR230","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1007\/s00438-020-01695-5","volume":"295","author":"Y Alhaidan","year":"2020","unstructured":"Alhaidan Y, Christesen HT, H\u00f8jlund K, Al Balwi MA, Brusgaard K (2020) A novel gene in early childhood diabetes: EDEM2 silencing decreases SLC2A2 and PXD1 expression, leading to impaired insulin secretion. Mol Genet Genomics 295(5):1253\u20131262. https:\/\/doi.org\/10.1007\/s00438-020-01695-5","journal-title":"Mol Genet Genomics"},{"issue":"10","key":"11453_CR231","doi-asserted-by":"publisher","DOI":"10.3390\/genes13101784","volume":"13","author":"V Z\u00e1mb\u00f3","year":"2022","unstructured":"Z\u00e1mb\u00f3 V, Orosz G, Szab\u00f3 L, Tibori K, Sipeki S, Moln\u00e1r K, Csala M, Kereszturi \u00c9 (2022) A single nucleotide polymorphism (rs3811792) affecting human SCD5 promoter activity is associated with diabetes mellitus. Genes (Basel) 13(10):1784. https:\/\/doi.org\/10.3390\/genes13101784","journal-title":"Genes (Basel)"},{"issue":"4","key":"11453_CR232","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1007\/s005920050087","volume":"34","author":"G De Filippo","year":"1997","unstructured":"De Filippo G, Pozzi N, Cosentini E, Cavalcanti M, Carel JC, Tamasi S, Franzese A, Pignata C (1997) Increased CD5+CD19+ B lymphocytes at the onset of type 1 diabetes in children. Acta Diabetol 34(4):271\u2013274. https:\/\/doi.org\/10.1007\/s005920050087","journal-title":"Acta Diabetol"},{"issue":"4","key":"11453_CR233","doi-asserted-by":"publisher","first-page":"E270","DOI":"10.1152\/ajpendo.00118.2014","volume":"308","author":"R Li","year":"2015","unstructured":"Li R, Xu X, Chen C, Wang Y, Gruzdev A, Zeldin DC, Wang DW (2015) CYP2J2 attenuates metabolic dysfunction in diabetic mice by reducing hepatic inflammation via the PPAR\u03b3. Am J Physiol Endocrinol Metab 308(4):E270\u2013E282. https:\/\/doi.org\/10.1152\/ajpendo.00118.2014","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"4","key":"11453_CR234","doi-asserted-by":"publisher","first-page":"999","DOI":"10.2337\/db08-1214","volume":"58","author":"DJ Friedman","year":"2009","unstructured":"Friedman DJ, Talbert ME, Bowden DW, Freedman BI, Mukanya Y, Enjyoji K, Robson SC (2009) Functional ENTPD1 polymorphisms in African Americans with diabetes and end-stage renal disease. Diabetes 58(4):999\u20131006. https:\/\/doi.org\/10.2337\/db08-1214","journal-title":"Diabetes"},{"issue":"3","key":"11453_CR235","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1038\/gene.2008.12","volume":"9","author":"HQ Qu","year":"2008","unstructured":"Qu HQ, Marchand L, Szymborski A, Grabs R, Polychronakos C (2008) The association between type 1 diabetes and the ITPR3 gene polymorphism due to linkage disequilibrium with HLA class II. Genes Immun 9(3):264\u2013266. https:\/\/doi.org\/10.1038\/gene.2008.12","journal-title":"Genes Immun"},{"key":"11453_CR236","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2024.103228","volume":"146","author":"JS Do","year":"2024","unstructured":"Do JS, Arribas-Layton D, Juan J, Garcia I, Saraswathy S, Qi M, Montero E, Reijonen H (2024) The CD318\/CD6 axis limits type 1 diabetes islet autoantigen-specific human T cell activation. J Autoimmun 146:103228. https:\/\/doi.org\/10.1016\/j.jaut.2024.103228","journal-title":"J Autoimmun"},{"issue":"5","key":"11453_CR237","doi-asserted-by":"publisher","DOI":"10.1002\/mgg3.1147","volume":"8","author":"GC Singh","year":"2020","unstructured":"Singh GC, Ahmed M, Zaid M, Hasnain S (2020) Biochemical, serological, and genetic aspects related to gene HLA-DQB1 and its association with type 1 diabetes mellitus (T1DM). Mol Genet Genomic Med 8(5):e1147. https:\/\/doi.org\/10.1002\/mgg3.1147","journal-title":"Mol Genet Genomic Med"},{"key":"11453_CR238","doi-asserted-by":"publisher","DOI":"10.17305\/bb.2025.12632","author":"K \u00c7ad\u0131rc\u0131","year":"2025","unstructured":"\u00c7ad\u0131rc\u0131 K, Bayrak M, Lazo\u011flu \u00d6zkaya A, Y\u0131lmaz GN, Pak N, Karahan B, Kiziltunc Ozmen H (2025) Serum NPTX2 and cognitive impairment in geriatric diabetes: a cross-sectional study. Biomol Biomed. https:\/\/doi.org\/10.17305\/bb.2025.12632","journal-title":"Biomol Biomed"},{"key":"11453_CR239","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-014-0163-2","volume":"14","author":"K Mohammedi","year":"2015","unstructured":"Mohammedi K, Bellili-Mu\u00f1oz N, Marklund SL, Driss F, Le Nagard H, Patente TA, Fumeron F, Roussel R, Hadjadj S, Marre M et al (2015) Plasma extracellular superoxide dismutase concentration, allelic variations in the SOD3 gene and risk of myocardial infarction and all-cause mortality in people with type 1 and type 2 diabetes. Cardiovasc Diabetol 14:845. https:\/\/doi.org\/10.1186\/s12933-014-0163-2","journal-title":"Cardiovasc Diabetol"},{"key":"11453_CR240","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1016\/j.lfs.2018.11.030","volume":"216","author":"SM Sartoretto","year":"2019","unstructured":"Sartoretto SM, Santos FF, Costa BP, Ceravolo GS, Santos-Eichler R, Carvalho MHC, Fortes ZB, Akamine EH (2019) Involvement of inducible nitric oxide synthase and estrogen receptor ESR2 (ER\u03b2) in the vascular dysfunction in female type 1 diabetic rats. Life Sci 216:279\u2013286. https:\/\/doi.org\/10.1016\/j.lfs.2018.11.030","journal-title":"Life Sci"},{"key":"11453_CR241","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2025.114647","author":"Z Liang","year":"2025","unstructured":"Liang Z, Zhang Q, Liu Y, Liu Z, Jiang Y, Yang X, Wei L, Wang G (2025) LOXL4, CREB5 and steroid hormone biosynthesis pathways are involved in type 1 diabetes with polycystic ovary-like changes. Eur J Obstet Gynecol Reprod Biol. https:\/\/doi.org\/10.1016\/j.ejogrb.2025.114647","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"4","key":"11453_CR242","doi-asserted-by":"publisher","first-page":"554","DOI":"10.2337\/db24-0553","volume":"74","author":"WX Yang","year":"2025","unstructured":"Yang WX, Su K, Liao MC, Zhou J, Peng J, H\u00e9bert MJ, Leal DN, Yamashita M, Miyata KN, Filep JG et al (2025) Renal tubule-specific angiotensinogen deletion attenuates SGLT2 expression and ameliorates diabetic kidney disease in murine models of type 1 diabetes. Diabetes 74(4):554\u2013568. https:\/\/doi.org\/10.2337\/db24-0553","journal-title":"Diabetes"},{"issue":"1","key":"11453_CR243","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1046\/j.1464-5491.2003.00786.x","volume":"20","author":"PB Leurs","year":"2003","unstructured":"Leurs PB, van Oerle R, Hamulyak K, Wolffenbuttel BH (2003) Tissue factor pathway inhibitor (TFPI) release after heparin stimulation is increased in type 1 diabetic patients with albuminuria. Diabet Med 20(1):16\u201322. https:\/\/doi.org\/10.1046\/j.1464-5491.2003.00786.x","journal-title":"Diabet Med"},{"issue":"8","key":"11453_CR244","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1002\/dmrr.1257","volume":"27","author":"K Takahashi","year":"2011","unstructured":"Takahashi K, Ohara M, Sasai T, Homma H, Nagasawa K, Takahashi T, Yamashina M, Ishii M, Fujiwara F, Kajiwara T et al (2011) Serum CXCL1 concentrations are elevated in type 1 diabetes mellitus, possibly reflecting activity of anti-islet autoimmune activity. Diabetes Metab Res Rev 27(8):830\u2013833. https:\/\/doi.org\/10.1002\/dmrr.1257","journal-title":"Diabetes Metab Res Rev"},{"issue":"13","key":"11453_CR245","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21134811","volume":"21","author":"M Terasaki","year":"2020","unstructured":"Terasaki M, Yashima H, Mori Y, Saito T, Matsui T, Hiromura M, Kushima H, Osaka N, Ohara M, Fukui T et al (2020) A dipeptidyl peptidase-4 inhibitor inhibits foam cell formation of macrophages in type 1 diabetes via suppression of CD36 and ACAT-1 expression. Int J Mol Sci 21(13):4811. https:\/\/doi.org\/10.3390\/ijms21134811","journal-title":"Int J Mol Sci"},{"issue":"3","key":"11453_CR246","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines13030615","volume":"13","author":"S Kovacevic","year":"2025","unstructured":"Kovacevic S, Jesic M, Zdravkovic V, Djordjevic S, Miolski J, Gasic V, Jelovac M, Ugrin M, Pavlovic S, Subosic B (2025) Association between hypertension, dipping status, and ACE and AGTR1 gene polymorphisms in adolescents with type 1 diabetes. Biomedicines 13(3):615. https:\/\/doi.org\/10.3390\/biomedicines13030615","journal-title":"Biomedicines"},{"issue":"3","key":"11453_CR247","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1007\/s13577-023-00868-9","volume":"36","author":"C Wu","year":"2023","unstructured":"Wu C, Liu W, Liu Y, Xu T, Li M, Li X, Wang Y, Meng G, Li L, Zheng R et al (2023) Human umbilical cord mesenchymal stem cell-derived TGFBI attenuates streptozotocin-induced type 1 diabetes mellitus by inhibiting T-cell proliferation. Hum Cell 36(3):997\u20131010. https:\/\/doi.org\/10.1007\/s13577-023-00868-9","journal-title":"Hum Cell"},{"key":"11453_CR248","doi-asserted-by":"publisher","DOI":"10.1016\/j.metop.2024.100320","volume":"24","author":"K Mangano","year":"2024","unstructured":"Mangano K, Diamantopoulos A, Vallianou NG, Stratigou T, Panagopoulos F, Kounatidis D, Dalamaga M, Fagone P, Nicoletti F (2024) Serum and urinary levels of MIF, CD74, DDT and CXCR4 among patients with type 1 diabetes mellitus, type 2 diabetes and healthy individuals: implications for further research. Metabol Open 24:100320. https:\/\/doi.org\/10.1016\/j.metop.2024.100320","journal-title":"Metabol Open"},{"issue":"1","key":"11453_CR249","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-021-02291-y","volume":"4","author":"M Kakoki","year":"2021","unstructured":"Kakoki M, Ramanathan PV, Hagaman JR, Grant R, Wilder JC, Taylor JM, Charles Jennette J, Smithies O, Maeda-Smithies N (2021) Cyanocobalamin prevents cardiomyopathy in type 1 diabetes by modulating oxidative stress and DNMT-SOCS1\/3-IGF-1 signaling. Commun Biol 4(1):775. https:\/\/doi.org\/10.1038\/s42003-021-02291-y","journal-title":"Commun Biol"},{"issue":"8","key":"11453_CR250","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1089\/dia.2014.0344","volume":"17","author":"L Xiu","year":"2015","unstructured":"Xiu L, Lin M, Liu W, Kong D, Liu Z, Zhang Y, Ouyang P, Liang Y, Zhong S, Chen C et al (2015) Association of DRD3, COMT, and SLC6A4 gene polymorphisms with type 2 diabetes in Southern Chinese: a hospital-based case-control study. Diabetes Technol Ther 17(8):580\u2013586. https:\/\/doi.org\/10.1089\/dia.2014.0344","journal-title":"Diabetes Technol Ther"},{"issue":"7","key":"11453_CR251","doi-asserted-by":"publisher","first-page":"761","DOI":"10.2174\/1389450123666220303092324","volume":"23","author":"R Basnet","year":"2022","unstructured":"Basnet R, Basnet TB, Basnet BB, Khadka S (2022) Overview on thioredoxin-interacting protein (TXNIP): a potential target for diabetes intervention. Curr Drug Targets 23(7):761\u2013767. https:\/\/doi.org\/10.2174\/1389450123666220303092324","journal-title":"Curr Drug Targets"},{"issue":"6","key":"11453_CR252","doi-asserted-by":"publisher","first-page":"921","DOI":"10.2337\/db23-0709","volume":"74","author":"DH McNitt","year":"2025","unstructured":"McNitt DH, Williams JM, Santitoro JG, Kim J, Thomas JW, Bonami RH (2025) Type 1 diabetes depends on CD4-driven expression of the transcriptional repressor Bcl6. Diabetes 74(6):921\u2013932. https:\/\/doi.org\/10.2337\/db23-0709","journal-title":"Diabetes"},{"issue":"1","key":"11453_CR253","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-39243-x","volume":"13","author":"SS Leung","year":"2023","unstructured":"Leung SS, Lenchik N, Mathews C, Pugliese A, McCarthy DA, Le Bagge S, Ewing A, Harris M, Radford KJ, Borg DJ et al (2023) Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes. Sci Rep 13(1):12948. https:\/\/doi.org\/10.1038\/s41598-023-39243-x","journal-title":"Sci Rep"},{"issue":"1","key":"11453_CR254","doi-asserted-by":"publisher","first-page":"89","DOI":"10.2337\/diacare.29.01.06.dc05-0757","volume":"29","author":"G Rudofsky Jr","year":"2006","unstructured":"Rudofsky G Jr, Schroedter A, Schlotterer A, Voron\u2019ko OE, Schlimme M, Tafel J, Isermann BH, Humpert PM, Morcos M, Bierhaus A et al (2006) Functional polymorphisms of UCP2 and UCP3 are associated with a reduced prevalence of diabetic neuropathy in patients with type 1 diabetes. Diabetes Care 29(1):89\u201394. https:\/\/doi.org\/10.2337\/diacare.29.01.06.dc05-0757","journal-title":"Diabetes Care"},{"key":"11453_CR255","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2021.119982","volume":"285","author":"NF Abo El-Magd","year":"2021","unstructured":"Abo El-Magd NF, Ramadan NM, Eraky SM (2021) The ameliorative effect of bromelain on STZ-induced type 1 diabetes in rats through Oxi-LDL\/LPA\/LPAR1 pathway. Life Sci 285:119982. https:\/\/doi.org\/10.1016\/j.lfs.2021.119982","journal-title":"Life Sci"},{"issue":"7","key":"11453_CR256","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.2337\/db25-0096","volume":"74","author":"A Bilal","year":"2025","unstructured":"Bilal A, Casu A, Yi F, Dutta T, Mucinski JM, Mercouffer G, Marak MC, Hompesch M, Kelley D, Pratley RE (2025) a randomized controlled, double-masked, crossover study of a GPR119 agonist on glucagon counterregulation during hypoglycemia in type 1 diabetes. Diabetes 74(7):1262\u20131272. https:\/\/doi.org\/10.2337\/db25-0096","journal-title":"Diabetes"},{"key":"11453_CR257","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2022.108928","volume":"235","author":"M Hoffmann","year":"2022","unstructured":"Hoffmann M, Enczmann J, Balz V, Kummer S, Reinauer C, D\u00f6ing C, F\u00f6rtsch K, Welters A, Kohns Vasconcelos M, Mayatepek E et al (2022) Interleukin-7 and soluble Interleukin-7 receptor levels in type 1 diabetes\u2014impact of IL7RA polymorphisms, HLA risk genotypes and clinical features. Clin Immunol 235:108928. https:\/\/doi.org\/10.1016\/j.clim.2022.108928","journal-title":"Clin Immunol"},{"issue":"12","key":"11453_CR258","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0143589","volume":"10","author":"N Assayag-Asherie","year":"2015","unstructured":"Assayag-Asherie N, Sever D, Bogdani M, Johnson P, Weiss T, Ginzberg A, Perles S, Weiss L, Sebban LE, Turley EA et al (2015) An CD44 be a mediator of cell destruction? The challenge of type 1 diabetes. PLoS ONE 10(12):e0143589. https:\/\/doi.org\/10.1371\/journal.pone.0143589","journal-title":"PLoS ONE"},{"key":"11453_CR259","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2020.154418","volume":"114","author":"J Qu","year":"2021","unstructured":"Qu J, Qu HQ, Bradfield JP, Glessner JT, Chang X, Tian L, March ME, Roizen JD, Sleiman PM, Hakonarson H (2021) Association of DLL1 with type 1 diabetes in patients characterized by low polygenic risk score. Metabolism 114:154418. https:\/\/doi.org\/10.1016\/j.metabol.2020.154418","journal-title":"Metabolism"},{"issue":"12","key":"11453_CR260","doi-asserted-by":"publisher","first-page":"3647","DOI":"10.1210\/jcem.80.12.8530614","volume":"80","author":"A Bereket","year":"1995","unstructured":"Bereket A, Lang CH, Blethen SL, Wilson TA (1995) Insulin-like growth factor-binding protein-2 and insulin: studies in children with type 1 diabetes mellitus and maturity-onset diabetes of the young. J Clin Endocrinol Metab 80(12):3647\u20133652. https:\/\/doi.org\/10.1210\/jcem.80.12.8530614","journal-title":"J Clin Endocrinol Metab"},{"key":"11453_CR261","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2025.115183","volume":"162","author":"Q Zhou","year":"2025","unstructured":"Zhou Q, Li M, Zhang J, Zhou X, Zhu Q, Ni H, Hu Y, Wang L, Ge Y, Xie K et al (2025) PPAR\u03b3 activation reduces pancreatic beta cell death in type 1 diabetes by decreasing heparanase-dependent insulitis. Int Immunopharmacol 162:115183. https:\/\/doi.org\/10.1016\/j.intimp.2025.115183","journal-title":"Int Immunopharmacol"},{"issue":"4","key":"11453_CR262","doi-asserted-by":"publisher","first-page":"553","DOI":"10.2337\/dc18-2176","volume":"42","author":"G Tapia","year":"2019","unstructured":"Tapia G, M\u00e5rild K, Dahl SR, Lund-Blix NA, Viken MK, Lie BA, Nj\u00f8lstad PR, Joner G, Skrivarhaug T, Cohen AS et al (2019) Maternal and newborn vitamin D-binding protein, vitamin D levels, vitamin D receptor genotype, and childhood type 1 diabetes. Diabetes Care 42(4):553\u2013559. https:\/\/doi.org\/10.2337\/dc18-2176","journal-title":"Diabetes Care"},{"issue":"1","key":"11453_CR263","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1074\/jbc.M210636200","volume":"278","author":"AJ MacFarlane","year":"2003","unstructured":"MacFarlane AJ, Burghardt KM, Kelly J, Simell T, Simell O, Altosaar I, Scott FW (2003) A type 1 diabetes-related protein from wheat (Triticum aestivum). cDNA clone of a wheat storage globulin, Glb1, linked to islet damage. J Biol Chem 278(1):54\u201363. https:\/\/doi.org\/10.1074\/jbc.M210636200","journal-title":"J Biol Chem"},{"issue":"2","key":"11453_CR264","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1007\/s10753-018-00954-3","volume":"42","author":"MR Davanso","year":"2019","unstructured":"Davanso MR, Caliari-Oliveira C, Couri CEB, Covas DT, de Oliveira Leal AM, Voltarelli JC, Malmegrim KCR (2019) Yaochite JNU. DPP-4 inhibition leads to decreased pancreatic inflammatory profile and increased frequency of regulatory T cells in experimental type 1 diabetes. Inflammation 42(2):449\u2013462. https:\/\/doi.org\/10.1007\/s10753-018-00954-3","journal-title":"Inflammation"},{"issue":"3","key":"11453_CR265","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1007\/s42000-022-00352-3","volume":"21","author":"\u00d6 Besci","year":"2022","unstructured":"Besci \u00d6, Patel KA, Y\u0131ld\u0131z G, T\u00fcfek\u00e7i \u00d6, Acinikli KY, Erba\u015f \u0130M, Abac\u0131 A, B\u00f6ber E, Bayram MT, Y\u0131lmaz \u015e et al (2022) Atypical comorbidities in a child considered to have type 1 diabetes led to the diagnosis of SLC29A3 spectrum disorder. Hormones (Athens) 21(3):501\u2013506. https:\/\/doi.org\/10.1007\/s42000-022-00352-3","journal-title":"Hormones (Athens)"},{"key":"11453_CR266","doi-asserted-by":"publisher","DOI":"10.1590\/1678-7757-2022-0176","volume":"30","author":"L Huang","year":"2022","unstructured":"Huang L, Chen J, Zuo Y, Li J, Yue Y, Wang M, Hao L (2022) Implications of lysyl oxidase-like protein 3 expression in the periodontium of diabetic rats. J Appl Oral Sci 30:e20220176. https:\/\/doi.org\/10.1590\/1678-7757-2022-0176","journal-title":"J Appl Oral Sci"},{"issue":"2","key":"11453_CR267","doi-asserted-by":"publisher","first-page":"137","DOI":"10.4274\/jcrpe.galenos.2023.2023-5-10","volume":"16","author":"E \u015eim\u015fek","year":"2024","unstructured":"\u015eim\u015fek E, \u00c7ilingir O, \u015eim\u015fek T, Kocagil S, Erzurumluo\u011flu G\u00f6kalp E, Demiral M, Binay C (2024) Screening of mutations in maturity-onset diabetes of the young-related genes and RFX6 in children with autoantibody-negative type 1 diabetes mellitus. J Clin Res Pediatr Endocrinol 16(2):137\u2013145. https:\/\/doi.org\/10.4274\/jcrpe.galenos.2023.2023-5-10","journal-title":"J Clin Res Pediatr Endocrinol"},{"issue":"6","key":"11453_CR268","doi-asserted-by":"publisher","DOI":"10.3390\/genes13061053","volume":"13","author":"P Babi\u0107","year":"2022","unstructured":"Babi\u0107 P, Filipovi\u0107 N, Hamzi\u0107 LF, Puljak L, Vukojevi\u0107 K, Benzon B (2022) Potential influence of age and diabetes mellitus type 1 on MSH2 (MutS homolog 2) expression in a rat kidney tissue. Genes 13(6):1053. https:\/\/doi.org\/10.3390\/genes13061053","journal-title":"Genes"},{"issue":"6","key":"11453_CR269","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1016\/j.metabol.2016.02.012","volume":"65","author":"MB Monteiro","year":"2016","unstructured":"Monteiro MB, Thieme K, Santos-Bezerra DP, Queiroz MS, Woronik V, Passarelli M, Machado UF, Giannella-Neto D, Oliveira-Souza M, Corr\u00eaa-Giannella ML (2016) Beta-2-microglobulin (B2M) expression in the urinary sediment correlates with clinical markers of kidney disease in patients with type 1 diabetes. Metabolism 65(6):816\u2013824. https:\/\/doi.org\/10.1016\/j.metabol.2016.02.012","journal-title":"Metabolism"},{"issue":"4","key":"11453_CR270","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/S1875-5364(24)60618-7","volume":"22","author":"W Yao","year":"2024","unstructured":"Yao W, Tao R, Wang K, Ding X (2024) Icariin attenuates vascular endothelial dysfunction by inhibiting inflammation through GPER\/Sirt1\/HMGB1 signaling pathway in type 1 diabetic rats. Chin J Nat Med 22(4):293\u2013306. https:\/\/doi.org\/10.1016\/S1875-5364(24)60618-7","journal-title":"Chin J Nat Med"},{"issue":"7","key":"11453_CR271","doi-asserted-by":"publisher","first-page":"544","DOI":"10.3109\/09537104.2012.735720","volume":"24","author":"SG Ma","year":"2013","unstructured":"Ma SG, Yang LX, Qiu XQ (2013) Assessment of the platelet parameters and serum butyrylcholinesterase activity in type 1 diabetes patients with ketoacidosis. Platelets 24(7):544\u2013548. https:\/\/doi.org\/10.3109\/09537104.2012.735720","journal-title":"Platelets"},{"issue":"2","key":"11453_CR272","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1111\/imm.12761","volume":"152","author":"GM Vaitaitis","year":"2017","unstructured":"Vaitaitis GM, Waid DM, Yussman MG, Wagner DH Jr (2017) CD40-mediated signalling influences trafficking, T-cell receptor expression, and T-cell pathogenesis, in the NOD model of type 1 diabetes. Immunology 152(2):243\u2013254. https:\/\/doi.org\/10.1111\/imm.12761","journal-title":"Immunology"},{"issue":"1","key":"11453_CR273","doi-asserted-by":"publisher","first-page":"171","DOI":"10.2337\/diabetes.55.01.06.db05-1129","volume":"55","author":"CH Lee","year":"2006","unstructured":"Lee CH, Chen YG, Chen J, Reifsnyder PC, Serreze DV, Clare-Salzler M, Rodriguez M, Wasserfall C, Atkinson MA, Leiter EH (2006) Novel leptin receptor mutation in NOD\/LtJ mice suppresses type 1 diabetes progression: II. Immunologic analysis. Diabetes 55(1):171\u2013178","journal-title":"Diabetes"},{"key":"11453_CR274","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/j.ebiom.2018.09.040","volume":"36","author":"ML Colli","year":"2018","unstructured":"Colli ML, Hill JLE, Marroqu\u00ed L, Chaffey J, Dos Santos RS, Leete P, de Coomans Brach\u00e8ne A, Paula FMM, de Op Beeck A, Castela A et al (2018) PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-\u03b1 and-\u03b3 via IRF1 induction. EBioMedicine 36:367\u2013375. https:\/\/doi.org\/10.1016\/j.ebiom.2018.09.040","journal-title":"EBioMedicine"},{"key":"11453_CR275","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.neuroscience.2021.03.009","volume":"463","author":"L Hao","year":"2021","unstructured":"Hao L, Mi J, Song L et al (2021) SLC40A1 mediates ferroptosis and cognitive dysfunction in type 1 diabetes. Neuroscience 463:216\u2013226. https:\/\/doi.org\/10.1016\/j.neuroscience.2021.03.009","journal-title":"Neuroscience"},{"key":"11453_CR276","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2350-7-54","volume":"7","author":"JL Santiago","year":"2006","unstructured":"Santiago JL, Mart\u00ednez A, de la Calle H, Fern\u00e1ndez-Arquero M, Figueredo MA, de la Concha EG, Urcelay E (2006) Evidence for the association of the SLC22A4 and SLC22A5 genes with type 1 diabetes: a case control study. BMC Med Genet 7:54. https:\/\/doi.org\/10.1186\/1471-2350-7-54","journal-title":"BMC Med Genet"},{"issue":"4","key":"11453_CR277","doi-asserted-by":"publisher","first-page":"328","DOI":"10.5301\/ejo.5000547","volume":"25","author":"K Blaslov","year":"2015","unstructured":"Blaslov K, Bulum T, Duvnjak L (2015) Circulating dipeptidyl peptidase-4 activity is associated with diabetic retinopathy in type 1 diabetic patients. Eur J Ophthalmol 25(4):328\u2013332. https:\/\/doi.org\/10.5301\/ejo.5000547","journal-title":"Eur J Ophthalmol"},{"issue":"3","key":"11453_CR278","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1007\/s00592-011-0299-4","volume":"48","author":"DA Chistiakov","year":"2011","unstructured":"Chistiakov DA, Potapov VA, Smetanina SA, Bel\u2019chikova LN, Suplotova LA, Nosikov VV (2011) The carriage of risk variants of CDKAL1 impairs beta-cell function in both diabetic and non-diabetic patients and reduces response to non-sulfonylurea and sulfonylurea agonists of the pancreatic KATP channel. Acta Diabetol 48(3):227\u2013235. https:\/\/doi.org\/10.1007\/s00592-011-0299-4","journal-title":"Acta Diabetol"},{"issue":"5","key":"11453_CR279","doi-asserted-by":"publisher","first-page":"F1484","DOI":"10.1152\/ajprenal.00183.2018","volume":"315","author":"HC Looker","year":"2018","unstructured":"Looker HC, Merchant ML, Rane MJ, Nelson RG, Kimmel PL, Rovin BH, Klein JB, Mauer M (2018) Urine inositol pentakisphosphate 2-kinase and changes in kidney structure in early diabetic kidney disease in type 1 diabetes. Am J Physiol Renal Physiol 315(5):F1484\u2013F1492. https:\/\/doi.org\/10.1152\/ajprenal.00183.2018. (CKD Biomarkers Consortium.)","journal-title":"Am J Physiol Renal Physiol"},{"key":"11453_CR280","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.bbacli.2015.06.001","volume":"4","author":"SJ Montano","year":"2015","unstructured":"Montano SJ, Gr\u00fcnler J, Nair D, Tekle M, Fernandes AP, Hua X, Holmgren A, Brismar K, Ungerstedt JS (2015) Glutaredoxin mediated redox effects of coenzyme Q10 treatment in type 1 and type 2 diabetes patients. BBA Clin 4:14\u201320. https:\/\/doi.org\/10.1016\/j.bbacli.2015.06.001","journal-title":"BBA Clin"},{"key":"11453_CR281","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/1641717","volume":"2021","author":"M He","year":"2021","unstructured":"He M, Long P, Chen T, Li K, Wei D, Zhang Y, Wang W, Hu Y, Ding Y, Wen A (2021) ALDH2\/SIRT1 contributes to type 1 and type 2 diabetes-induced retinopathy through depressing oxidative stress. Oxid Med Cell Longev 2021:1641717. https:\/\/doi.org\/10.1155\/2021\/1641717","journal-title":"Oxid Med Cell Longev"},{"key":"11453_CR282","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2020.124682","volume":"406","author":"C Qianru","year":"2021","unstructured":"Qianru C, Xueyuan H, Bing Z, Qing Z, Kaixin Z, Shu L (2021) Regulation of H2S-induced necroptosis and inflammation in broiler bursa of Fabricius by the miR-15b-5p\/TGFBR3 axis and the involvement of oxidative stress in this process. J Hazard Mater 406:124682. https:\/\/doi.org\/10.1016\/j.jhazmat.2020.124682","journal-title":"J Hazard Mater"},{"issue":"20","key":"11453_CR283","doi-asserted-by":"publisher","DOI":"10.3390\/nu14204372","volume":"14","author":"A Mentxaka","year":"2022","unstructured":"Mentxaka A, G\u00f3mez-Ambrosi J, Ram\u00edrez B, Rodr\u00edguez A, Becerril S, Neira G, Valent\u00ed V, Moncada R, Silva C, Unamuno X et al (2022) Netrin-1 promotes visceral adipose tissue inflammation in obesity and is associated with insulin resistance. Nutrients 14(20):4372. https:\/\/doi.org\/10.3390\/nu14204372","journal-title":"Nutrients"},{"issue":"825","key":"11453_CR284","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.adh1178","volume":"17","author":"H Cai","year":"2024","unstructured":"Cai H, Zhang J, Xu H, Sun W, Wu W, Dong C, Zhou P, Xue C, Nan Y, Ni Y et al (2024) ALOX5 drives the pyroptosis of CD4+ T cells and tissue inflammation in rheumatoid arthritis. Sci Signal 17(825):eadh1178","journal-title":"Sci Signal"},{"issue":"8","key":"11453_CR285","doi-asserted-by":"publisher","DOI":"10.3390\/nu13082716","volume":"13","author":"M Salaga","year":"2021","unstructured":"Salaga M, Bartoszek A, Binienda A, Krajewska JB, Fabisiak A, Mosi\u0144ska P, Dziedziczak K, Niewinna K, Talar M, Tarasiuk A et al (2021) Activation of free fatty acid receptor 4 affects intestinal inflammation and improves colon permeability in mice. Nutrients 13(8):2716. https:\/\/doi.org\/10.3390\/nu13082716","journal-title":"Nutrients"},{"issue":"5","key":"11453_CR286","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1016\/j.joca.2019.11.002","volume":"28","author":"N Sharma","year":"2020","unstructured":"Sharma N, Drobinski P, Kayed A, Chen Z, Kjelgaard-Petersen CF, Gantzel T, Karsdal MA, Michaelis M, Ladel C, Bay-Jensen AC et al (2020) Inflammation and joint destruction may be linked to the generation of cartilage metabolites of ADAMTS-5 through activation of toll-like receptors. Osteoarthritis Cartilage 28(5):658\u2013668. https:\/\/doi.org\/10.1016\/j.joca.2019.11.002","journal-title":"Osteoarthritis Cartilage"},{"issue":"1","key":"11453_CR287","doi-asserted-by":"publisher","DOI":"10.3390\/antiox13010124","volume":"13","author":"A Pazos-P\u00e9rez","year":"2024","unstructured":"Pazos-P\u00e9rez A, Pi\u00f1eiro-Ramil M, Franco-Trepat E, Alonso-P\u00e9rez A, Guill\u00e1n-Fresco M, Crespo-Golmar A, L\u00f3pez-Fag\u00fandez M, Aranda JC, Bravo SB, Jorge-Mora A et al (2024) The hepatokine RBP4 links metabolic diseases to articular inflammation. Antioxidants 13(1):124. https:\/\/doi.org\/10.3390\/antiox13010124","journal-title":"Antioxidants"},{"issue":"1","key":"11453_CR288","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1042\/CS20180836","volume":"133","author":"Y Wang","year":"2019","unstructured":"Wang Y, Xie T, Zhang D, Leung PS (2019) GPR120 protects lipotoxicity-induced pancreatic \u03b2-cell dysfunction through regulation of PDX1 expression and inhibition of islet inflammation. Clin Sci (Lond) 133(1):101\u2013116. https:\/\/doi.org\/10.1042\/CS20180836","journal-title":"Clin Sci (Lond)"},{"issue":"11","key":"11453_CR289","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1016\/j.bbadis.2008.08.011","volume":"1782","author":"KH Weylandt","year":"2008","unstructured":"Weylandt KH, Nadolny A, Kahlke L, K\u00f6hnke T, Schm\u00f6cker C, Wang J, Lauwers GY, Glickman JN, Kang JX (2008) Reduction of inflammation and chronic tissue damage by omega-3 fatty acids in fat-1 transgenic mice with pancreatitis. Biochim Biophys Acta 1782(11):634\u2013641. https:\/\/doi.org\/10.1016\/j.bbadis.2008.08.011","journal-title":"Biochim Biophys Acta"},{"issue":"6","key":"11453_CR290","doi-asserted-by":"publisher","DOI":"10.3390\/v14061210","volume":"14","author":"CW Lehman","year":"2022","unstructured":"Lehman CW, Smith A, Kelly J, Jacobs JL, Dinman JD, Kehn-Hall K (2022) EGR1 upregulation during encephalitic viral infections contributes to inflammation and cell death. Viruses 14(6):1210. https:\/\/doi.org\/10.3390\/v14061210","journal-title":"Viruses"},{"issue":"9","key":"11453_CR291","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19092516","volume":"19","author":"E Piktel","year":"2018","unstructured":"Piktel E, Levental I, Durna\u015b B, Janmey PA, Bucki R (2018) Plasma gelsolin: indicator of inflammation and its potential as a diagnostic tool and therapeutic target. Int J Mol Sci 19(9):2516. https:\/\/doi.org\/10.3390\/ijms19092516","journal-title":"Int J Mol Sci"},{"issue":"3","key":"11453_CR292","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1097\/FJC.0000000000001177","volume":"79","author":"X Wu","year":"2022","unstructured":"Wu X, Fan D, Chen B (2022) LncRNA NEAT1 accelerates the proliferation, oxidative stress, inflammation, and fibrosis and suppresses the apoptosis through the miR-423-5p\/GLIPR2 axis in diabetic nephropathy. J Cardiovasc Pharmacol 79(3):342\u2013354. https:\/\/doi.org\/10.1097\/FJC.0000000000001177","journal-title":"J Cardiovasc Pharmacol"},{"key":"11453_CR293","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2013.00010","volume":"4","author":"WX Carroll","year":"2013","unstructured":"Carroll WX, Kalupahana NS, Booker SL, Siriwardhana N, Lemieux M, Saxton AM, Moustaid-Moussa N (2013) Angiotensinogen gene silencing reduces markers of lipid accumulation and inflammation in cultured adipocytes. Front Endocrinol (Lausanne) 4:10. https:\/\/doi.org\/10.3389\/fendo.2013.00010","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"4","key":"11453_CR294","doi-asserted-by":"publisher","first-page":"60","DOI":"10.15586\/aei.v53i4.1380","volume":"53","author":"X Shi","year":"2025","unstructured":"Shi X, Ding J, Zeng B (2025) Deptor alleviates LPS-induced inflammation and ER stress in WI-38 cells. Allergol Immunopathol (Madr) 53(4):60\u201367. https:\/\/doi.org\/10.15586\/aei.v53i4.1380","journal-title":"Allergol Immunopathol (Madr)"},{"key":"11453_CR295","doi-asserted-by":"publisher","DOI":"10.1186\/s12950-018-0189-4","volume":"15","author":"JK Yamamoto-Furusho","year":"2018","unstructured":"Yamamoto-Furusho JK, Fonseca-Camarillo G, Furuzawa-Carballeda J, Sarmiento-Aguilar A, Barreto-Zu\u00f1iga R, Mart\u00ednez-Benitez B, Lara-Velazquez MA (2018) Caspase recruitment domain (CARD) family (CARD9, CARD10, CARD11, CARD14 and CARD15) are increased during active inflammation in patients with inflammatory bowel disease. J Inflamm 15:13. https:\/\/doi.org\/10.1186\/s12950-018-0189-4","journal-title":"J Inflamm"},{"issue":"1","key":"11453_CR296","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-022-01022-0","volume":"14","author":"AP Tsai","year":"2022","unstructured":"Tsai AP, Dong C, Lin PB, Messenger EJ, Casali BT, Moutinho M, Liu Y, Oblak AL, Lamb BT, Landreth GE et al (2022) PLCG2 is associated with the inflammatory response and is induced by amyloid plaques in Alzheimer\u2019s disease. Genome Med 14(1):17. https:\/\/doi.org\/10.1186\/s13073-022-01022-0","journal-title":"Genome Med"},{"issue":"24","key":"11453_CR297","doi-asserted-by":"publisher","first-page":"4930","DOI":"10.1182\/blood-2013-02-486217","volume":"121","author":"K De Filippo","year":"2013","unstructured":"De Filippo K, Dudeck A, Hasenberg M, Nye E, van Rooijen N, Hartmann K, Gunzer M, Roers A, Hogg N (2013) Mast cell and macrophage chemokines CXCL1\/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation. Blood 121(24):4930\u20134937. https:\/\/doi.org\/10.1182\/blood-2013-02-486217","journal-title":"Blood"},{"key":"11453_CR298","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2021.108628","volume":"208","author":"NG Menon","year":"2021","unstructured":"Menon NG, Goyal R, Lema C, Woods PS, Tanguay AP, Morin AA, Das N, Jay GD, Krawetz RJ, Dufour A et al (2021) Proteoglycan 4 (PRG4) expression and function in dry eye associated inflammation. Exp Eye Res 208:108628. https:\/\/doi.org\/10.1016\/j.exer.2021.108628","journal-title":"Exp Eye Res"},{"issue":"3","key":"11453_CR299","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/j.jhep.2018.04.006","volume":"69","author":"L Zhao","year":"2018","unstructured":"Zhao L, Zhang C, Luo X, Wang P, Zhou W, Zhong S, Xie Y, Jiang Y, Yang P, Tang R et al (2018) CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis. J Hepatol 69(3):705\u2013717. https:\/\/doi.org\/10.1016\/j.jhep.2018.04.006","journal-title":"J Hepatol"},{"issue":"2","key":"11453_CR300","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/ajh.2010.210","volume":"24","author":"MM Fung","year":"2011","unstructured":"Fung MM, Rao F, Poddar S, Mahata M, Khandrika S, Mahata SK, O\u2019Connor DT (2011) Early inflammatory and metabolic changes in association with AGTR1 polymorphisms in prehypertensive subjects. Am J Hypertens 24(2):225\u2013233. https:\/\/doi.org\/10.1038\/ajh.2010.210","journal-title":"Am J Hypertens"},{"issue":"5","key":"11453_CR301","doi-asserted-by":"publisher","DOI":"10.1016\/j.jlr.2023.100370","volume":"64","author":"A Chattopadhyay","year":"2023","unstructured":"Chattopadhyay A, Mukherjee P, Sulaiman D, Wang H, Girjalva V, Dorreh N, Jacobs JP, Delk S, Moolenaar WH, Navab M et al (2023) Role of enterocyte Enpp2 and autotaxin in regulating lipopolysaccharide levels, systemic inflammation, and atherosclerosis. J Lipid Res 64(5):100370. https:\/\/doi.org\/10.1016\/j.jlr.2023.100370","journal-title":"J Lipid Res"},{"issue":"2","key":"11453_CR302","doi-asserted-by":"publisher","first-page":"201","DOI":"10.7417\/CT.2025.5206","volume":"176","author":"D Chaitra","year":"2025","unstructured":"Chaitra D, Pai Divya N, Raghavendra H, Kamath D (2025) Exploring The Role of Serum Netrin 1 Levels in Diabetic Foot Syndrome And Uncomplicated Type 2 Diabetes Mellitus: A Comparative Analysis. Clin Ter 176(2):201\u2013206. https:\/\/doi.org\/10.7417\/CT.2025.5206","journal-title":"Clin Ter"},{"key":"11453_CR303","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.jsbmb.2018.10.022","volume":"187","author":"N Nejatian","year":"2019","unstructured":"Nejatian N, H\u00e4fner AK, Shoghi F, Badenhoop K, Penna-Martinez M (2019) 5-Lipoxygenase (ALOX5): Genetic susceptibility to type 2 diabetes and vitamin D effects on monocytes. J Steroid Biochem Mol Biol 187:52\u201357. https:\/\/doi.org\/10.1016\/j.jsbmb.2018.10.022","journal-title":"J Steroid Biochem Mol Biol"},{"issue":"1","key":"11453_CR304","doi-asserted-by":"publisher","first-page":"3422","DOI":"10.1038\/s41467-025-58706-5","volume":"16","author":"X Chen","year":"2025","unstructured":"Chen X, Shao J, Brandenburger I, Qian W, Hahnefeld L, Bonnavion R, Cho H, Wang S, Hidalgo J, Wettschureck N et al (2025) FFAR4-mediated IL-6 release from islet macrophages promotes insulin secretion and is compromised in type-2 diabetes. Nat Commun 16(1):3422. https:\/\/doi.org\/10.1038\/s41467-025-58706-5","journal-title":"Nat Commun"},{"issue":"5","key":"11453_CR305","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1002\/humu.9034","volume":"19","author":"HF Gu","year":"2002","unstructured":"Gu HF (2002) Genetic variation screening and association studies of the adenylate cyclase activating polypeptide 1 (ADCYAP1) gene in patients with type 2 diabetes. Hum Mutat 19(5):572\u2013573. https:\/\/doi.org\/10.1002\/humu.9034","journal-title":"Hum Mutat"},{"issue":"1","key":"11453_CR306","doi-asserted-by":"publisher","first-page":"2242997","DOI":"10.1080\/21623945.2023.2242997","volume":"12","author":"S Hetty","year":"2023","unstructured":"Hetty S, Vranic M, Kamble PG, Lundqvist MH, Pereira MJ, Eriksson JW (2023) CABLES1 expression is reduced in human subcutaneous adipose tissue in obesity and type 2 diabetes but may not directly impact adipocyte glucose and lipid metabolism. Adipocyte 12(1):2242997. https:\/\/doi.org\/10.1080\/21623945.2023.2242997","journal-title":"Adipocyte"},{"issue":"9","key":"11453_CR307","doi-asserted-by":"publisher","first-page":"4727","DOI":"10.1007\/s12035-021-02455-1","volume":"58","author":"M Joshi","year":"2021","unstructured":"Joshi M, Shah DP, Krishnakumar A (2021) Extreme glycemic fluctuations debilitate NRG1, ErbB receptors and Olig1 function: association with regeneration, cognition and mood alterations during diabetes. Mol Neurobiol 58(9):4727\u20134744. https:\/\/doi.org\/10.1007\/s12035-021-02455-1","journal-title":"Mol Neurobiol"},{"issue":"12","key":"11453_CR308","doi-asserted-by":"publisher","first-page":"e1686","DOI":"10.1210\/clinem\/dgad303","volume":"108","author":"H Lian","year":"2023","unstructured":"Lian H, Gong S, Li M, Wang X, Wang F, Cai X, Liu W, Luo Y, Zhang S, Zhang R et al (2023) Prevalence and clinical characteristics of PDX1 variant induced diabetes in Chinese early-onset type 2 diabetes. J Clin Endocrinol Metab 108(12):e1686\u2013e1694. https:\/\/doi.org\/10.1210\/clinem\/dgad303","journal-title":"J Clin Endocrinol Metab"},{"key":"11453_CR309","doi-asserted-by":"publisher","DOI":"10.26402\/jpp.2023.2.03.10.26402\/jpp.2023.2.03","author":"RQ Ke","year":"2023","unstructured":"Ke RQ, Wang Y, Hong SH, Xiao LX (2023) Anti-diabetic effect of quercetin in type 2 diabetes mellitus by regulating the microRNA-92b-3p\/EGR1 axis. J Physiol Pharmacol. https:\/\/doi.org\/10.26402\/jpp.2023.2.03.10.26402\/jpp.2023.2.03","journal-title":"J Physiol Pharmacol"},{"issue":"1","key":"11453_CR310","doi-asserted-by":"publisher","first-page":"5","DOI":"10.3892\/mmr.2024.13371","volume":"31","author":"Q Zhang","year":"2025","unstructured":"Zhang Q, Chen Y, Huang W, Zhou J, Yang D (2025) Melittin promotes the proliferation of Schwann cells in hyperglycemic environment by up-regulating the Crabp2\/Wnt\/\u03b2-catenin signaling pathway. Mol Med Rep 31(1):5. https:\/\/doi.org\/10.3892\/mmr.2024.13371","journal-title":"Mol Med Rep"},{"issue":"1","key":"11453_CR311","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1186\/s12881-020-00999-y","volume":"21","author":"J Kang","year":"2020","unstructured":"Kang J, Guan RC, Zhao Y, Chen Y (2020) Obesity-related loci in TMEM18, CDKAL1 and FAIM2 are associated with obesity and type 2 diabetes in Chinese Han patients. BMC Med Genet 21(1):65. https:\/\/doi.org\/10.1186\/s12881-020-00999-y","journal-title":"BMC Med Genet"},{"issue":"1","key":"11453_CR312","doi-asserted-by":"publisher","DOI":"10.1177\/1470320317752955","volume":"19","author":"YC Qiao","year":"2018","unstructured":"Qiao YC, Wang M, Pan YH, Zhang XX, Tian F, Chen YL, Zhao HL (2018) The relationship between ACE\/AGT gene polymorphisms and the risk of diabetic retinopathy in Chinese patients with type 2 diabetes. J Renin Angiotensin Aldosterone Syst 19(1):1470320317752955. https:\/\/doi.org\/10.1177\/1470320317752955","journal-title":"J Renin Angiotensin Aldosterone Syst"},{"issue":"3","key":"11453_CR313","doi-asserted-by":"publisher","first-page":"173","DOI":"10.5001\/omj.2010.52","volume":"25","author":"RS El-Hagracy","year":"2010","unstructured":"El-Hagracy RS, Kamal GM, Sabry IM, Saad AA, Abou El Ezz NF, Nasr HA (2010) Tissue factor, tissue factor pathway inhibitor and factor VII activity in cardiovascular complicated type 2 diabetes mellitus. Oman Med J 25(3):173\u2013178. https:\/\/doi.org\/10.5001\/omj.2010.52","journal-title":"Oman Med J"},{"issue":"1\u20132","key":"11453_CR314","doi-asserted-by":"publisher","first-page":"133","DOI":"10.7754\/clin.lab.2012.120225","volume":"59","author":"SM Sajadi","year":"2013","unstructured":"Sajadi SM, Khoramdelazad H, Hassanshahi G, Rafatpanah H, Hosseini J, Mahmoodi M, Arababadi MK, Derakhshan R, Hasheminasabzavareh R, Hosseini-Zijoud SM et al (2013) Plasma levels of CXCL1 (GRO-alpha) and CXCL10 (IP-10) are elevated in type 2 diabetic patients: evidence for the involvement of inflammation and angiogenesis\/angiostasis in this disease state. Clin Lab 59(1\u20132):133\u2013137. https:\/\/doi.org\/10.7754\/clin.lab.2012.120225","journal-title":"Clin Lab"},{"issue":"2","key":"11453_CR315","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.numecd.2015.10.009","volume":"26","author":"F Tavaglione","year":"2016","unstructured":"Tavaglione F, Filardi T, Fallarino M, Mandosi E, Turinese I, Rossetti M, Lenzi A, Morano S (2016) The SNP rs9677 of VPAC1 gene is associated with glycolipid control and heart function in female patients with type 2 diabetes: a follow-up study. Nutr Metab Cardiovasc Dis 26(2):109\u2013113. https:\/\/doi.org\/10.1016\/j.numecd.2015.10.009","journal-title":"Nutr Metab Cardiovasc Dis"},{"issue":"1","key":"11453_CR316","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1007\/s12013-014-0202-3","volume":"71","author":"Z Deng","year":"2015","unstructured":"Deng Z, Shen J, Ye J, Shu Q, Zhao J, Fang M, Zhang T (2015) Association between single nucleotide polymorphisms of delta\/notch-like epidermal growth factor (EGF)-related receptor (DNER) and Delta-like 1 Ligand (DLL 1) with the risk of type 2 diabetes mellitus in a Chinese Han population. Cell Biochem Biophys 71(1):331\u2013335. https:\/\/doi.org\/10.1007\/s12013-014-0202-3","journal-title":"Cell Biochem Biophys"},{"issue":"2","key":"11453_CR317","doi-asserted-by":"publisher","first-page":"222","DOI":"10.4093\/dmj.2020.0053","volume":"44","author":"JS Moon","year":"2020","unstructured":"Moon JS, Karunakaran U, Suma E, Chung SM, Won KC (2020) The role of CD36 in type 2 diabetes mellitus: \u03b2-cell dysfunction and beyond. Diabetes Metab J 44(2):222\u2013233. https:\/\/doi.org\/10.4093\/dmj.2020.0053","journal-title":"Diabetes Metab J"},{"issue":"3","key":"11453_CR318","doi-asserted-by":"publisher","first-page":"203","DOI":"10.33594\/000000702","volume":"58","author":"M Ihsan","year":"2024","unstructured":"Ihsan M, Khan NU, Asim N, Ismail M, Almutairi MH, Ali I, Adams BD (2024) Significant association of candidate genes (AGTR1 and TGF-\u03921) polymorphism with diabetic nephropathy in diabetes mellitus type 2 patients. Cell Physiol Biochem 58(3):203\u2013211. https:\/\/doi.org\/10.33594\/000000702","journal-title":"Cell Physiol Biochem"},{"key":"11453_CR319","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2022.106086","volume":"176","author":"L Chen","year":"2022","unstructured":"Chen L, Yin Z, Qin X, Zhu X, Chen X, Ding G, Sun D, Wu NN, Fei J, Bi Y, Zhang J et al (2022) CD74 ablation rescues type 2 diabetes mellitus-induced cardiac remodeling and contractile dysfunction through pyroptosis-evoked regulation of ferroptosis. Pharmacol Res 176:106086. https:\/\/doi.org\/10.1016\/j.phrs.2022.106086","journal-title":"Pharmacol Res"},{"issue":"1","key":"11453_CR320","doi-asserted-by":"publisher","DOI":"10.1136\/bmjdrc-2020-001242","volume":"8","author":"L Opazo-R\u00edos","year":"2020","unstructured":"Opazo-R\u00edos L, Sanchez Matus Y, Rodrigues-D\u00edez RR, Carpio D, Droguett A, Egido J, Gomez-Guerrero C, Mezzano S (2020) Anti-inflammatory, antioxidant and renoprotective effects of SOCS1 mimetic peptide in the BTBR ob\/ob mouse model of type 2 diabetes. BMJ Open Diabetes Res Care 8(1):e001242. https:\/\/doi.org\/10.1136\/bmjdrc-2020-001242","journal-title":"BMJ Open Diabetes Res Care"},{"issue":"9","key":"11453_CR321","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1517\/14728222.12.9.1097","volume":"12","author":"S Matsuzaki","year":"2008","unstructured":"Matsuzaki S, Tohyama M (2008) Regulation of pituitary adenylyl cyclase-activating polypeptide (PACAP, ADCYAP1: adenylyl cyclase-activating polypeptide 1) in the treatment of schizophrenia. Expert Opin Ther Targets 12(9):1097\u20131108. https:\/\/doi.org\/10.1517\/14728222.12.9.1097","journal-title":"Expert Opin Ther Targets"},{"issue":"1633","key":"11453_CR322","doi-asserted-by":"publisher","first-page":"20130144","DOI":"10.1098\/rstb.2013.0144","volume":"369","author":"T Kimura","year":"2013","unstructured":"Kimura T, Whitcomb DJ, Jo J, Regan P, Piers T, Heo S, Brown C, Hashikawa T, Murayama M, Seok H et al (2013) Microtubule-associated protein tau is essential for long-term depression in the hippocampus. Philos Trans R Soc Lond B Biol Sci 369(1633):20130144. https:\/\/doi.org\/10.1098\/rstb.2013.0144","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"11453_CR323","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.jpsychires.2020.05.030","volume":"129","author":"Q Yao","year":"2020","unstructured":"Yao Q, Li Y (2020) Study of decreased serum levels of retinol binding protein 4 in major depressive disorder. J Psychiatr Res 129:24\u201330. https:\/\/doi.org\/10.1016\/j.jpsychires.2020.05.030","journal-title":"J Psychiatr Res"},{"issue":"8","key":"11453_CR324","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1016\/j.jpsychires.2013.03.018","volume":"47","author":"J Mosebach","year":"2013","unstructured":"Mosebach J, Keilhoff G, Gos T, Schiltz K, Schoeneck L, Dobrowolny H, Mawrin C, M\u00fcller S, Schroeter ML, Bernstein HG et al (2013) Increased nuclear Olig1-expression in the pregenual anterior cingulate white matter of patients with major depression: a regenerative attempt to compensate oligodendrocyte loss? J Psychiatr Res 47(8):1069\u20131079. https:\/\/doi.org\/10.1016\/j.jpsychires.2013.03.018","journal-title":"J Psychiatr Res"},{"key":"11453_CR325","doi-asserted-by":"publisher","DOI":"10.1016\/j.plefa.2021.102313","volume":"171","author":"M Gu","year":"2021","unstructured":"Gu M, Li X, Yan L, Zhang Y, Yang L, Li S, Song C (2021) Endogenous \u03c9-3 fatty acids in Fat-1 mice attenuated depression-like behaviors, spatial memory impairment and relevant changes induced by olfactory bulbectomy. Prostaglandins Leukot Essent Fatty Acids 171:102313. https:\/\/doi.org\/10.1016\/j.plefa.2021.102313","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"issue":"3","key":"11453_CR326","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1006\/mcne.1993.1028","volume":"4","author":"WH Lee","year":"1993","unstructured":"Lee WH, Bondy C (1993) Induction of EGR1\/NGFI-A gene expression by spreading depression and focal cerebral ischemia. Mol Cell Neurosci 4(3):225\u2013230. https:\/\/doi.org\/10.1006\/mcne.1993.1028","journal-title":"Mol Cell Neurosci"},{"issue":"4","key":"11453_CR327","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1007\/s12640-020-00234-9","volume":"38","author":"CR Yang","year":"2020","unstructured":"Yang CR, Ning L, Zhou FH, Sun Q, Meng HP, Han Z, Liu Y, Huang W, Liu S, Li XH et al (2020) Downregulation of adhesion molecule CHL1 in B cells but not T cells of patients with major depression and in the brain of mice with chronic stress. Neurotox Res 38(4):914\u2013928. https:\/\/doi.org\/10.1007\/s12640-020-00234-9","journal-title":"Neurotox Res"},{"issue":"1","key":"11453_CR328","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1055\/s-0035-1565241","volume":"49","author":"S Ozsoy","year":"2016","unstructured":"Ozsoy S, Olguner Eker O, Abdulrezzak U (2016) The effects of antidepressants on neuropeptide Y in patients with depression and anxiety. Pharmacopsychiatry 49(1):26\u201331. https:\/\/doi.org\/10.1055\/s-0035-1565241","journal-title":"Pharmacopsychiatry"},{"issue":"5","key":"11453_CR329","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1176\/appi.ajp.2020.20050653","volume":"178","author":"S Costi","year":"2021","unstructured":"Costi S, Morris LS, Kirkwood KA, Hoch M, Corniquel M, Vo-Le B, Iqbal T, Chadha N, Pizzagalli DA, Whitton A et al (2021) Impact of the KCNQ2\/3 channel opener Ezogabine on reward circuit activity and clinical symptoms in depression: results from a randomized controlled trial. Am J Psychiatry 178(5):437\u2013446. https:\/\/doi.org\/10.1176\/appi.ajp.2020.20050653","journal-title":"Am J Psychiatry"},{"key":"11453_CR330","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2023.114357","volume":"444","author":"Y Guo","year":"2023","unstructured":"Guo Y, Jiang Z, Jin T, Huang J, Sun X (2023) Activation of calcium-sensing receptors in the basolateral nucleus of the amygdala inhibits food intake and induces anxiety-depressive-like emotions via dopamine system. Behav Brain Res 444:114357. https:\/\/doi.org\/10.1016\/j.bbr.2023.114357","journal-title":"Behav Brain Res"},{"issue":"4","key":"11453_CR331","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1097\/YPG.0b013e3282fb7fd6","volume":"18","author":"S L\u00f3pez-Le\u00f3n","year":"2008","unstructured":"L\u00f3pez-Le\u00f3n S, Janssens AC, Tiemeier H, Hofman A, Aulchenko YS, Snijders PJ, Claes S, Oostra BA, van Duijn CM (2008) Angiotensinogen M235T polymorphism and symptoms of depression in a population-based study and a family-based study. Psychiatr Genet 18(4):162\u2013166. https:\/\/doi.org\/10.1097\/YPG.0b013e3282fb7fd6","journal-title":"Psychiatr Genet"},{"issue":"11","key":"11453_CR332","doi-asserted-by":"publisher","first-page":"2037","DOI":"10.3390\/genes14112037","volume":"14","author":"M Paolini","year":"2023","unstructured":"Paolini M, Fortaner-Uy\u00e0 L, Lorenzi C, Spadini S, Maccario M, Zanardi R, Colombo C, Poletti S, Benedetti F (2023) Association between NTRK2 polymorphisms, hippocampal volumes and treatment resistance in major depressive disorder. Genes (Basel) 14(11):2037. https:\/\/doi.org\/10.3390\/genes14112037","journal-title":"Genes (Basel)"},{"key":"11453_CR333","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1016\/j.jad.2019.02.042","volume":"249","author":"G Fanelli","year":"2019","unstructured":"Fanelli G, Benedetti F, Wang SM, Lee SJ, Jun TY, Masand PS, Patkar AA, Han C, Serretti A, Pae CU et al (2019) Reduced CXCL1\/GRO chemokine plasma levels are a possible biomarker of elderly depression. J Affect Disord 249:410\u2013417. https:\/\/doi.org\/10.1016\/j.jad.2019.02.042","journal-title":"J Affect Disord"},{"issue":"1","key":"11453_CR334","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-020-01130-8","volume":"11","author":"S Bai","year":"2021","unstructured":"Bai S, Wang W, Wang T, Li J, Zhang S, Chen Z, Qi X, Chen J, Cheng K, Xie P (2021) CD36 deficiency affects depressive-like behaviors possibly by modifying gut microbiota and the inflammasome pathway in mice. Transl Psychiatry 11(1):16. https:\/\/doi.org\/10.1038\/s41398-020-01130-8","journal-title":"Transl Psychiatry"},{"issue":"2","key":"11453_CR335","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1002\/hbm.21445","volume":"34","author":"WD Taylor","year":"2013","unstructured":"Taylor WD, Zhao Z, Ashley-Koch A, Payne ME, Steffens DC, Krishnan RR, Hauser E, MacFall JR (2013) Fiber tract-specific white matter lesion severity findings in late-life depression and by AGTR1 A1166C genotype. Hum Brain Mapp 34(2):295\u2013303. https:\/\/doi.org\/10.1002\/hbm.21445","journal-title":"Hum Brain Mapp"},{"issue":"7","key":"11453_CR336","doi-asserted-by":"publisher","first-page":"2201","DOI":"10.1007\/s00213-022-06107-7","volume":"239","author":"Z Sun","year":"2022","unstructured":"Sun Z, Zhan H, Wang C, Guo P (2022) Shanzhiside methylester protects against depression by inhibiting inflammation via the miRNA-155-5p\/SOCS1 axis. Psychopharmacology 239(7):2201\u20132213. https:\/\/doi.org\/10.1007\/s00213-022-06107-7","journal-title":"Psychopharmacology"},{"issue":"3","key":"11453_CR337","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.pscychresns.2012.04.005","volume":"212","author":"PS Ho","year":"2013","unstructured":"Ho PS, Ho KK, Huang WS, Yen CH, Shih MC, Shen LH, Ma KH, Huang SY (2013) Association study of serotonin transporter availability and SLC6A4 gene polymorphisms in patients with major depression. Psychiatry Res 212(3):216\u2013222. https:\/\/doi.org\/10.1016\/j.pscychresns.2012.04.005","journal-title":"Psychiatry Res"},{"issue":"7","key":"11453_CR338","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1002\/ajmg.b.32571","volume":"174","author":"C Schartner","year":"2017","unstructured":"Schartner C, Scholz CJ, Weber H, Post A, Freudenberg F, Gr\u00fcnewald L, Reif A (2017) The regulation of tetraspanin 8 gene expression-a potential new mechanism in the pathogenesis of bipolar disorder. Am J Med Genet B Neuropsychiatr Genet 174(7):740\u2013750. https:\/\/doi.org\/10.1002\/ajmg.b.32571","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"issue":"14","key":"11453_CR339","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.2217\/pgs-2020-0058","volume":"21","author":"SS Aghabozorg Afjeh","year":"2020","unstructured":"Aghabozorg Afjeh SS, Shams J, Hamednia S, Boshehri B, Olfat A, Omrani MD (2020) Investigation of the impact of an ADCY2 polymorphism as a predictive biomarker in bipolar disorder, suicide tendency and response to lithium carbonate therapy: the first report from Iran. Pharmacogenomics 21(14):1011\u20131020. https:\/\/doi.org\/10.2217\/pgs-2020-0058","journal-title":"Pharmacogenomics"},{"key":"11453_CR340","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.redox.2016.08.006","volume":"9","author":"RH Du","year":"2016","unstructured":"Du RH, Wu FF, Lu M, Shu XD, Ding JH, Wu G, Hu G (2016) Uncoupling protein 2 modulation of the NLRP3 inflammasome in astrocytes and its implications in depression. Redox Biol 9:178\u2013187. https:\/\/doi.org\/10.1016\/j.redox.2016.08.006","journal-title":"Redox Biol"},{"issue":"6","key":"11453_CR341","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26062501","volume":"26","author":"D Szukiewicz","year":"2025","unstructured":"Szukiewicz D (2025) Potential therapeutic exploitation of G protein-coupled receptor 120 (GPR120\/FFAR4) signaling in obesity-related metabolic disorders. Int J Mol Sci 26(6):2501. https:\/\/doi.org\/10.3390\/ijms26062501","journal-title":"Int J Mol Sci"},{"issue":"2","key":"11453_CR342","doi-asserted-by":"publisher","first-page":"147","DOI":"10.3109\/02770903.2012.757776","volume":"50","author":"GA Thun","year":"2013","unstructured":"Thun GA, Imboden M, Berger W, Rochat T, Probst-Hensch NM (2013) The association of a variant in the cell cycle control gene CCND1 and obesity on the development of asthma in the Swiss SAPALDIA study. J Asthma 50(2):147\u2013154. https:\/\/doi.org\/10.3109\/02770903.2012.757776","journal-title":"J Asthma"},{"issue":"5","key":"11453_CR343","doi-asserted-by":"publisher","first-page":"6099","DOI":"10.1096\/fj.201901979RR","volume":"34","author":"M Kilicarslan","year":"2020","unstructured":"Kilicarslan M, de Weijer BA, Simonyt\u00e9 Sj\u00f6din K, Aryal P, Ter Horst KW, Cakir H, Romijn JA, Ackermans MT, Janssen IM, Berends FJ et al (2020) RBP4 increases lipolysis in human adipocytes and is associated with increased lipolysis and hepatic insulin resistance in obese women. FASEB J 34(5):6099\u20136110. https:\/\/doi.org\/10.1096\/fj.201901979RR","journal-title":"FASEB J"},{"issue":"1","key":"11453_CR344","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabet.2023.101507","volume":"50","author":"Y Kouidrat","year":"2024","unstructured":"Kouidrat Y, Le Collen L, Vaxillaire M, Dechaume A, Toussaint B, Vaillant E, Amanzougarene S, Derhourhi M, Delemer B, Azahaf M et al (2024) Dominant PDX1 deficiency causes highly penetrant diabetes at different ages, associated with obesity and exocrine pancreatic deficiency: lessons for precision medicine. Diabetes Metab 50(1):101507. https:\/\/doi.org\/10.1016\/j.diabet.2023.101507","journal-title":"Diabetes Metab"},{"issue":"43","key":"11453_CR345","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2402954121","volume":"121","author":"R Tang","year":"2024","unstructured":"Tang R, Harasymowicz NS, Wu CL, Choi YR, Lenz K, Oswald SJ, Guilak F (2024) Gene therapy for fat-1 prevents obesity-induced metabolic dysfunction, cellular senescence, and osteoarthritis. Proc Natl Acad Sci U S A 121(43):e2402954121. https:\/\/doi.org\/10.1073\/pnas.2402954121","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"11453_CR346","doi-asserted-by":"publisher","first-page":"E269","DOI":"10.1152\/ajpendo.00524.2015","volume":"311","author":"M Ruebel","year":"2016","unstructured":"Ruebel M, Shankar K, Gaddy D, Lindsey F, Badger T, Andres A (2016) Maternal obesity is associated with ovarian inflammation and upregulation of early growth response factor 1. Am J Physiol Endocrinol Metab 311(1):E269\u2013E277. https:\/\/doi.org\/10.1152\/ajpendo.00524.2015","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"11453_CR347","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2024.101993","volume":"87","author":"H Yu","year":"2024","unstructured":"Yu H, Chiang A, Rubinstein M, Low MJ (2024) The homeodomain transcription factor Six3 regulates hypothalamic Pomc expression and its absence from POMC neurons induces hyperphagia and mild obesity in male mice. Mol Metab 87:101993. https:\/\/doi.org\/10.1016\/j.molmet.2024.101993","journal-title":"Mol Metab"},{"issue":"7","key":"11453_CR348","doi-asserted-by":"publisher","first-page":"750","DOI":"10.2174\/1389203720666190125105401","volume":"20","author":"Y Wu","year":"2019","unstructured":"Wu Y, He H, Cheng Z, Bai Y, Ma X (2019) The Role of Neuropeptide Y and Peptide YY in the Development of Obesity via Gut-brain Axis. Curr Protein Pept Sci 20(7):750\u2013758. https:\/\/doi.org\/10.2174\/1389203720666190125105401","journal-title":"Curr Protein Pept Sci"},{"issue":"1","key":"11453_CR349","doi-asserted-by":"publisher","DOI":"10.1590\/0001-3765202320220052","volume":"95","author":"A Scharf","year":"2023","unstructured":"Scharf A, Bezerra FF, Zembrzuski VM, Fonseca ACPD, Gusm\u00e3o L, Faerstein E (2023) Investigation of associations of European, African, Amerindian genomic ancestries and MC4R, FTO, FAIM2, BDNF loci with obesity-related traits in Rio de Janeiro, Brazil. An Acad Bras Cienc 95(1):e20220052. https:\/\/doi.org\/10.1590\/0001-3765202320220052","journal-title":"An Acad Bras Cienc"},{"issue":"10","key":"11453_CR350","doi-asserted-by":"publisher","first-page":"715","DOI":"10.4149\/BLL_2021_114","volume":"122","author":"Y Repchuk","year":"2021","unstructured":"Repchuk Y, Sydorchuk LP, Sydorchuk AR, Fedonyuk LY, Kamyshnyi O, Korovenkova O, Plehutsa IM, Dzhuryak VS, Myshkovskii YM, Iftoda OM et al (2021) Linkage of blood pressure, obesity and diabetes mellitus with angiotensinogen gene (AGT 704T>C\/rs699) polymorphism in hypertensive patients. Bratisl Lek Listy 122(10):715\u2013720. https:\/\/doi.org\/10.4149\/BLL_2021_114","journal-title":"Bratisl Lek Listy"},{"issue":"2","key":"11453_CR351","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1016\/j.molmet.2015.11.005","volume":"5","author":"A Caron","year":"2015","unstructured":"Caron A, Labb\u00e9 SM, Lanfray D, Blanchard PG, Villot R, Roy C, Sabatini DM, Richard D, Laplante M (2015) Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity. Mol Metab 5(2):102\u2013112. https:\/\/doi.org\/10.1016\/j.molmet.2015.11.005","journal-title":"Mol Metab"},{"key":"11453_CR352","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2202-12-117","volume":"12","author":"M Rask-Andersen","year":"2011","unstructured":"Rask-Andersen M, Alm\u00e9n MS, Olausen HR, Olszewski PK, Eriksson J, Chavan RA, Levine AS, Fredriksson R, Schi\u00f6th HB (2011) Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway. BMC Neurosci 12:117. https:\/\/doi.org\/10.1186\/1471-2202-12-117","journal-title":"BMC Neurosci"},{"issue":"12","key":"11453_CR353","doi-asserted-by":"publisher","first-page":"2747","DOI":"10.1038\/s12276-024-01367-z","volume":"56","author":"HS Lee","year":"2024","unstructured":"Lee HS, Kim BK, Lee SY, Kwon H, Park HW (2024) Essential role of Card11 in airway hyperresponsiveness in high-fat diet-induced obese mice. Exp Mol Med 56(12):2747\u20132754. https:\/\/doi.org\/10.1038\/s12276-024-01367-z","journal-title":"Exp Mol Med"},{"issue":"5","key":"11453_CR354","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/s0049-3848(00)00424-2","volume":"101","author":"A Vambergue","year":"2001","unstructured":"Vambergue A, Rugeri L, Gaveriaux V, Devos P, Martin A, Fermon C, Fontaine P, Jude B (2001) Factor VII, tissue factor pathway inhibitor, and monocyte tissue factor in diabetes mellitus: influence of type of diabetes, obesity index, and age. Thromb Res 101(5):367\u2013375. https:\/\/doi.org\/10.1016\/s0049-3848(00)00424-2","journal-title":"Thromb Res"},{"key":"11453_CR355","doi-asserted-by":"publisher","first-page":"11674","DOI":"10.1038\/ncomms11674","volume":"7","author":"T Zhang","year":"2016","unstructured":"Zhang T, Tseng C, Zhang Y, Sirin O, Corn PG, Li-Ning-Tapia EM, Troncoso P, Davis J, Pettaway C, Ward J et al (2016) CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment. Nat Commun 7:11674. https:\/\/doi.org\/10.1038\/ncomms11674","journal-title":"Nat Commun"},{"issue":"2","key":"11453_CR356","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1016\/j.bbadis.2018.11.009","volume":"1865","author":"JE Nahon","year":"2019","unstructured":"Nahon JE, Hoekstra M, van Harmelen V, Rensen PCN, van Willems Dijk K, Kooijman S, Van Eck M (2019) Proteoglycan 4 deficiency protects against glucose intolerance and fatty liver disease in diet-induced obese mice. Biochim Biophys Acta Mol Basis Dis 1865(2):494\u2013501. https:\/\/doi.org\/10.1016\/j.bbadis.2018.11.009","journal-title":"Biochim Biophys Acta Mol Basis Dis"},{"issue":"5","key":"11453_CR357","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1071\/RD18292","volume":"31","author":"RX Wu","year":"2019","unstructured":"Wu RX, Dong YY, Yang PW, Wang L, Deng YH, Zhang HW, Huang XY (2019) CD36- and obesity-associated granulosa cells dysfunction. Reprod Fertil Dev 31(5):993\u20131001. https:\/\/doi.org\/10.1071\/RD18292","journal-title":"Reprod Fertil Dev"},{"issue":"1","key":"11453_CR358","doi-asserted-by":"publisher","first-page":"53","DOI":"10.4149\/BLL_2023_008","volume":"124","author":"M Adiyeva","year":"2023","unstructured":"Adiyeva M, Aukenov N, Nurzhanova A, Slamkhanova N, Kerimkulova A (2023) The effect of AGTR1, AGT, LPL, ADRB2 gene polymorphisms on central obesity in adolescents of the Kazakh population. Bratisl Lek Listy 124(1):53\u201358. https:\/\/doi.org\/10.4149\/BLL_2023_008","journal-title":"Bratisl Lek Listy"},{"issue":"3","key":"11453_CR359","doi-asserted-by":"publisher","DOI":"10.1093\/stcltm\/szae101","volume":"14","author":"Y Tang","year":"2025","unstructured":"Tang Y, Cheng J, Huang C, Qiu P, Li J, Chen YE, Mizrak D, Yang B (2025) TGFBR3 dependent mechanism of TGFB2 in smooth muscle cell differentiation and implications for TGFB2-related aortic aneurysm. Stem Cells Transl Med 14(3):szae101. https:\/\/doi.org\/10.1093\/stcltm\/szae101","journal-title":"Stem Cells Transl Med"},{"issue":"4","key":"11453_CR360","doi-asserted-by":"publisher","first-page":"H721","DOI":"10.1152\/ajpheart.00115.2022","volume":"323","author":"GV Halade","year":"2022","unstructured":"Halade GV, Kain V, Hossain S, Parcha V, Limdi NA, Arora P (2022) Arachidonate 5-lipoxygenase is essential for biosynthesis of specialized pro-resolving mediators and cardiac repair in heart failure. Am J Physiol Heart Circ Physiol 323(4):H721\u2013H737. https:\/\/doi.org\/10.1152\/ajpheart.00115.2022","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"11453_CR361","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/6129748","volume":"2019","author":"Z Wang","year":"2019","unstructured":"Wang Z, Ye D, Ye J, Wang M, Liu J, Jiang H, Xu Y, Zhang J, Chen J, Wan J (2019) ADAMTS-5 decreases in coronary arteries and plasma from patients with coronary artery disease. Dis Markers 2019:6129748. https:\/\/doi.org\/10.1155\/2019\/6129748","journal-title":"Dis Markers"},{"issue":"2","key":"11453_CR362","doi-asserted-by":"publisher","DOI":"10.31083\/j.rcm2402033","volume":"24","author":"Y Ji","year":"2023","unstructured":"Ji Y, Du S, Tang C, Song J, Gu X (2023) The value of RBP4 in assessing coronary artery elasticity in patients with coronary heart disease and type 2 diabetes mellitus. Rev Cardiovasc Med 24(2):33. https:\/\/doi.org\/10.31083\/j.rcm2402033","journal-title":"Rev Cardiovasc Med"},{"issue":"3","key":"11453_CR363","doi-asserted-by":"publisher","first-page":"1966","DOI":"10.1002\/ehf2.13262","volume":"8","author":"S Mao","year":"2021","unstructured":"Mao S, Ma H, Chen P, Liang Y, Zhang M, Hinek A (2021) Fat-1 transgenic mice rich in endogenous omega-3 fatty acids are protected from lipopolysaccharide-induced cardiac dysfunction. ESC Heart Fail 8(3):1966\u20131978. https:\/\/doi.org\/10.1002\/ehf2.13262","journal-title":"ESC Heart Fail"},{"key":"11453_CR364","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2024.1487668","volume":"11","author":"LM Khachigian","year":"2024","unstructured":"Khachigian LM (2024) Early growth response-1, a dynamic conduit in cardiovascular disease. Front Cardiovasc Med 11:1487668. https:\/\/doi.org\/10.3389\/fcvm.2024.1487668","journal-title":"Front Cardiovasc Med"},{"issue":"10","key":"11453_CR365","doi-asserted-by":"publisher","first-page":"2092","DOI":"10.1038\/s41401-024-01296-7","volume":"45","author":"DN Ji","year":"2024","unstructured":"Ji DN, Jin SD, Jiang Y, Xu FY, Fan SW, Zhao YL, Liu XQ, Sun H, Cheng WZ, Zhang XY et al (2024) CircNSD1 promotes cardiac fibrosis through targeting the miR-429-3p\/SULF1\/Wnt\/\u03b2-catenin signaling pathway. Acta Pharmacol Sin 45(10):2092\u20132106. https:\/\/doi.org\/10.1038\/s41401-024-01296-7","journal-title":"Acta Pharmacol Sin"},{"key":"11453_CR366","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2018.01281","volume":"9","author":"CMJ Tan","year":"2018","unstructured":"Tan CMJ, Green P, Tapoulal N, Lewandowski AJ, Leeson P, Herring N (2018) The role of neuropeptide Y in cardiovascular health and disease. Front Physiol 9:1281. https:\/\/doi.org\/10.3389\/fphys.2018.01281","journal-title":"Front Physiol"},{"key":"11453_CR367","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2024.131887","volume":"403","author":"P Xu","year":"2024","unstructured":"Xu P, Cao Y, Zhang S, Liu X, Zhang M, Zhang C (2024) The predictive value of serum Dickkopf-1, Dickkopf-3 level to coronary artery disease and acute coronary syndrome. Int J Cardiol 403:131887. https:\/\/doi.org\/10.1016\/j.ijcard.2024.131887","journal-title":"Int J Cardiol"},{"issue":"19","key":"11453_CR368","doi-asserted-by":"publisher","DOI":"10.3390\/cells11193075","volume":"11","author":"H Chu","year":"2022","unstructured":"Chu H, Qin Z, Ma J, Xie Y, Shi H, Gu J, Shi B (2022) Calcium-sensing receptor (CaSR)-mediated intracellular communication in cardiovascular diseases. Cells 11(19):3075. https:\/\/doi.org\/10.3390\/cells11193075","journal-title":"Cells"},{"key":"11453_CR369","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2025.123816","author":"S Yuan","year":"2025","unstructured":"Yuan S, Yang S, Guo Y, Huang Z, Li W, Meng C, Xie Y, Li S, Chen X, Long H et al (2025) GLIPR2 regulates EndoMT and cardiac fibrosis after AMI via PDGFRL\/AKT\/mTOR signaling pathway. Life Sci. https:\/\/doi.org\/10.1016\/j.lfs.2025.123816","journal-title":"Life Sci"},{"issue":"22","key":"11453_CR370","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.124.034257","volume":"13","author":"H Zhong","year":"2024","unstructured":"Zhong H, Wu M, Xie H, Chen X, Li J, Duan Z, Chen H, Liu Z, Liao W, Chen Y (2024) Fas apoptosis inhibitory molecule 2 inhibits pathological cardiac hypertrophy by regulating the MAPK signaling pathway. J Am Heart Assoc 13(22):e034257. https:\/\/doi.org\/10.1161\/JAHA.124.034257","journal-title":"J Am Heart Assoc"},{"issue":"5","key":"11453_CR371","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1161\/ATVBAHA.124.318374","volume":"44","author":"A Daugherty","year":"2024","unstructured":"Daugherty A, Sawada H, Sheppard MB, Lu HS (2024) Angiotensinogen as a therapeutic target for cardiovascular and metabolic diseases. Arterioscler Thromb Vasc Biol 44(5):1021\u20131030. https:\/\/doi.org\/10.1161\/ATVBAHA.124.318374","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"11","key":"11453_CR372","doi-asserted-by":"publisher","first-page":"1925","DOI":"10.1517\/13543784.10.11.1925","volume":"10","author":"B Kaiser","year":"2001","unstructured":"Kaiser B, Hoppensteadt DA, Fareed J (2001) Tissue factor pathway inhibitor: an update of potential implications in the treatment of cardiovascular disorders. Expert Opin Investig Drugs 10(11):1925\u20131935. https:\/\/doi.org\/10.1517\/13543784.10.11.1925","journal-title":"Expert Opin Investig Drugs"},{"issue":"3","key":"11453_CR373","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1007\/s12026-024-09455-y","volume":"72","author":"T Wang","year":"2024","unstructured":"Wang T, Wang X, Teng Y, Wu L, Zhu F, Ma D, Wang H, Liu X (2024) APLAID complicated with arrhythmogenic dilated cardiomyopathy caused by a novel PLCG2 variant. Immunol Res 72(3):512\u2013519. https:\/\/doi.org\/10.1007\/s12026-024-09455-y","journal-title":"Immunol Res"},{"key":"11453_CR374","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.674498","volume":"8","author":"CL Wu","year":"2021","unstructured":"Wu CL, Yin R, Wang SN, Ying R (2021) A review of CXCL1 in cardiac fibrosis. Front Cardiovasc Med 8:674498. https:\/\/doi.org\/10.3389\/fcvm.2021.674498","journal-title":"Front Cardiovasc Med"},{"key":"11453_CR375","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.112507","volume":"137","author":"W Zhou","year":"2024","unstructured":"Zhou W, Wang N, Dong S, Huan Z, Sui L, Ge X (2024) PRG4 mitigates hemorrhagic shock-induced cardiac injury by inhibiting mitochondrial dysregulation, oxidative stress and NLRP3-mediated pyroptosis. Int Immunopharmacol 137:112507. https:\/\/doi.org\/10.1016\/j.intimp.2024.112507","journal-title":"Int Immunopharmacol"},{"issue":"1","key":"11453_CR376","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1093\/cvr\/cvaa319","volume":"118","author":"H Shu","year":"2022","unstructured":"Shu H, Peng Y, Hang W, Nie J, Zhou N, Wang DW (2022) The role of CD36 in cardiovascular disease. Cardiovasc Res 118(1):115\u2013129. https:\/\/doi.org\/10.1093\/cvr\/cvaa319","journal-title":"Cardiovasc Res"},{"key":"11453_CR377","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2023.154722","volume":"113","author":"XH Wei","year":"2023","unstructured":"Wei XH, Liu WJ, Jiang W, Lan TH, Pan H, Ma MY, You LZ, Shang HC (2023) XinLi formula, a traditional Chinese decoction, alleviates chronic heart failure via regulating the interaction of AGTR1 and AQP1. Phytomedicine 113:154722. https:\/\/doi.org\/10.1016\/j.phymed.2023.154722","journal-title":"Phytomedicine"},{"issue":"8","key":"11453_CR378","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1161\/ATVBAHA.122.317682","volume":"42","author":"E Karshovska","year":"2022","unstructured":"Karshovska E, Mohibullah R, Zhu M, Zahedi F, Thomas D, Magkrioti C, Geissler C, Megens RTA, Bianchini M, Nazari-Jahantigh M et al (2022) Endothelial ENPP2 (ectonucleotide pyrophosphatase\/phosphodiesterase 2) increases atherosclerosis in female and male mice. Arterioscler Thromb Vasc Biol 42(8):1023\u20131036. https:\/\/doi.org\/10.1161\/ATVBAHA.122.317682","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"8","key":"11453_CR379","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.34067\/KID.0001492021","volume":"2","author":"TN Caza","year":"2021","unstructured":"Caza TN, Hassen SI, Kenan DJ, Storey A, Arthur JM, Herzog C, Edmondson RD, Bourne TD, Beck LH Jr, Larsen CP (2021) Transforming growth factor beta receptor 3 (TGFBR3)-associated membranous nephropathy. Kidney360 2(8):1275\u20131286. https:\/\/doi.org\/10.34067\/KID.0001492021","journal-title":"Kidney360"},{"issue":"1","key":"11453_CR380","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2022.11733","volume":"25","author":"X Chen","year":"2022","unstructured":"Chen X, Xie H, Liu Y, Ou Q, Deng S (2022) Interference of ALOX5 alleviates inflammation and fibrosis in high glucose\u2011induced renal mesangial cells. Exp Ther Med 25(1):34. https:\/\/doi.org\/10.3892\/etm.2022.11733","journal-title":"Exp Ther Med"},{"issue":"1","key":"11453_CR381","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-022-01254-x","volume":"7","author":"L Yang","year":"2022","unstructured":"Yang L, Wang B, Guo F, Huang R, Liang Y, Li L, Tao S, Yin T, Fu P et al (2022) FFAR4 improves the senescence of tubular epithelial cells by AMPK\/SirT3 signaling in acute kidney injury. Signal Transduct Target Ther 7(1):384. https:\/\/doi.org\/10.1038\/s41392-022-01254-x","journal-title":"Signal Transduct Target Ther"},{"issue":"5","key":"11453_CR382","doi-asserted-by":"publisher","first-page":"F1166","DOI":"10.1152\/ajprenal.90550.2008","volume":"296","author":"B Fogelgren","year":"2009","unstructured":"Fogelgren B, Yang S, Sharp IC, Huckstep OJ, Ma W, Somponpun SJ, Carlson EC, Uyehara CF, Lozanoff S (2009) Deficiency in Six2 during prenatal development is associated with reduced nephron number, chronic renal failure, and hypertension in Br\/+ adult mice. Am J Physiol Renal Physiol 296(5):F1166\u2013F1178. https:\/\/doi.org\/10.1152\/ajprenal.90550.2008","journal-title":"Am J Physiol Renal Physiol"},{"issue":"12","key":"11453_CR383","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1038\/s41434-020-0160-x","volume":"27","author":"X Jiang","year":"2020","unstructured":"Jiang X, Ru Q, Li P, Ge X, Shao K, Xi L, Xu B, Wang Q, Huang S (2020) LncRNA SNHG16 induces proliferation and fibrogenesis via modulating miR-141-3p and CCND1 in diabetic nephropathy. Gene Ther 27(12):557\u2013566. https:\/\/doi.org\/10.1038\/s41434-020-0160-x","journal-title":"Gene Ther"},{"issue":"8","key":"11453_CR384","doi-asserted-by":"publisher","first-page":"2243","DOI":"10.4049\/jimmunol.2000448","volume":"205","author":"S Taylor","year":"2020","unstructured":"Taylor S, Whitfield M, Barratt J, Didangelos A (2020) The metalloproteinase ADAMTS5 is expressed by interstitial inflammatory cells in IgA nephropathy and is proteolytically active on the kidney matrix. J Immunol 205(8):2243\u20132254. https:\/\/doi.org\/10.4049\/jimmunol.2000448","journal-title":"J Immunol"},{"key":"11453_CR385","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2024.1381060","volume":"15","author":"T Chen","year":"2024","unstructured":"Chen T, Liu Y, Wu S, Long S, Feng L, Lu W, Chen W, Hong G, Zhou L, Wang F et al (2024) The association of RBP4 with chronic kidney diseases in southern Chinese population. Front Endocrinol (Lausanne) 15:1381060. https:\/\/doi.org\/10.3389\/fendo.2024.1381060","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"5","key":"11453_CR386","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.2337\/db21-0645","volume":"71","author":"LM Wiggenhauser","year":"2022","unstructured":"Wiggenhauser LM, Metzger L, Bennewitz K, Soleymani S, Boger M, Tabler CT, Hausser I, Sticht C, Wohlfart P, Volk N et al (2022) Pdx1 knockout leads to a diabetic nephropathy- like phenotype in zebrafish and identifies phosphatidylethanolamine as metabolite promoting early diabetic kidney damage. Diabetes 71(5):1073\u20131080. https:\/\/doi.org\/10.2337\/db21-0645","journal-title":"Diabetes"},{"key":"11453_CR387","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10822","volume":"7","author":"HY Gee","year":"2016","unstructured":"Gee HY, Sadowski CE, Aggarwal PK, Porath JD, Yakulov TA, Schueler M, Lovric S, Ashraf S, Braun DA, Halbritter J et al (2016) FAT1 mutations cause a glomerulotubular nephropathy. Nat Commun 7:10822. https:\/\/doi.org\/10.1038\/ncomms10822","journal-title":"Nat Commun"},{"issue":"1","key":"11453_CR388","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.matbio.2006.09.005","volume":"26","author":"RM Baxter","year":"2007","unstructured":"Baxter RM, Crowell TP, George JA, Getman ME, Gardner H (2007) The plant pathogenesis related protein GLIPR-2 is highly expressed in fibrotic kidney and promotes epithelial to mesenchymal transition in vitro. Matrix Biol 26(1):20\u201329. https:\/\/doi.org\/10.1016\/j.matbio.2006.09.005","journal-title":"Matrix Biol"},{"issue":"10","key":"11453_CR389","doi-asserted-by":"publisher","first-page":"2115","DOI":"10.1161\/HYPERTENSIONAHA.122.18731","volume":"79","author":"EO Cruz-L\u00f3pez","year":"2022","unstructured":"Cruz-L\u00f3pez EO, Ye D, Wu C, Lu HS, Uijl E, Mirabito Colafella KM, Danser AHJ (2022) Angiotensinogen suppression: a new tool to treat cardiovascular and renal disease. Hypertension 79(10):2115\u20132126. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.122.18731","journal-title":"Hypertension"},{"issue":"5","key":"11453_CR390","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-018-0483-3","volume":"9","author":"C Wang","year":"2018","unstructured":"Wang C, Dai H, Xiong Z, Song Q, Zou Z, Li M, Nie J, Bai X, Chen Z (2018) Loss of DEPTOR in renal tubules protects against cisplatin-induced acute kidney injury. Cell Death Dis 9(5):441. https:\/\/doi.org\/10.1038\/s41419-018-0483-3","journal-title":"Cell Death Dis"},{"issue":"3","key":"11453_CR391","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1007\/s11239-025-03077-3","volume":"58","author":"R Brook","year":"2025","unstructured":"Brook R, Suleiman M, Rigano J, Lui B, Nandurkar H, Ho P, Lim HY (2025) Tissue factor pathway inhibitor levels and atherothrombotic events in patients with chronic kidney disease or diabetes. J Thromb Thrombolysis 58(3):391\u2013400. https:\/\/doi.org\/10.1007\/s11239-025-03077-3","journal-title":"J Thromb Thrombolysis"},{"issue":"5","key":"11453_CR392","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1007\/s10753-024-01993-9","volume":"47","author":"X Li","year":"2024","unstructured":"Li X, Zhou X, Ping X, Zhao X, Kang H, Zhang Y, Ma Y, Ge H, Liu L, Li R et al (2024) Ombined plasma Olink proteomics and transcriptomics identifies CXCL1 and TNFRSF12A as potential predictive and diagnostic inflammatory markers for acute kidney injury. Inflammation 47(5):1547\u20131563. https:\/\/doi.org\/10.1007\/s10753-024-01993-9","journal-title":"Inflammation"},{"issue":"1","key":"11453_CR393","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-025-04396-6","volume":"26","author":"I Trutin","year":"2025","unstructured":"Trutin I, Oleti\u0107 L, Gale\u0161i\u0107 Ljubanovi\u0107 D, Krgovi\u0107 D, Niku\u0161eva Marti\u0107 T (2025) How does LAMB2 contribute to kidney disease? Insights from a pediatric case. BMC Nephrol 26(1):465. https:\/\/doi.org\/10.1186\/s12882-025-04396-6","journal-title":"BMC Nephrol"},{"key":"11453_CR394","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2025.1605631","volume":"16","author":"W Li","year":"2025","unstructured":"Li W, Wang Y (2025) The potential biomarker value of soluble CD36 in the treatment of diabetic kidney disease: evidence from GLP-1 and insulin interventions. Front Endocrinol (Lausanne) 16:1605631. https:\/\/doi.org\/10.3389\/fendo.2025.1605631","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"1","key":"11453_CR395","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1186\/s12882-024-03569-z","volume":"25","author":"A Al-Maraghi","year":"2024","unstructured":"Al-Maraghi A, Aamer W, Ziab M, Aliyev E, Elbashir N, Hussein S, Palaniswamy S, Anand D, Love DR, Charles A et al (2024) A loss-of-function AGTR1 variant in a critically-ill infant with renal tubular dysgenesis: case presentation and literature review. BMC Nephrol 25(1):139. https:\/\/doi.org\/10.1186\/s12882-024-03569-z","journal-title":"BMC Nephrol"},{"issue":"45","key":"11453_CR396","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000035794","volume":"102","author":"F Dou","year":"2023","unstructured":"Dou F, Liu Q, Lv S, Xu Q, Wang X, Liu S, Liu G (2023) FN1 and TGFBI are key biomarkers of macrophage immune injury in diabetic kidney disease. Medicine (Baltimore) 102(45):e35794. https:\/\/doi.org\/10.1097\/MD.0000000000035794","journal-title":"Medicine (Baltimore)"},{"issue":"6","key":"11453_CR397","doi-asserted-by":"publisher","DOI":"10.3390\/cells13060489","volume":"13","author":"JX Zhou","year":"2024","unstructured":"Zhou JX, Cheng AS, Chen L, Li LX, Agborbesong E, Torres VE, Harris PC, Li X (2024) CD74 promotes cyst growth and renal fibrosis in autosomal dominant polycystic kidney disease. Cells 13(6):489. https:\/\/doi.org\/10.3390\/cells13060489","journal-title":"Cells"},{"issue":"8","key":"11453_CR398","doi-asserted-by":"publisher","first-page":"2775","DOI":"10.3390\/jcm12082775","volume":"12","author":"D Mirra","year":"2023","unstructured":"Mirra D, Esposito R, Spaziano G, Rafaniello C, Iovino P, Cione E, Gallelli L, D\u2019Agostino B (2023) Association between sex-related ALOX5 gene polymorphisms and lung atopy risk. J Clin Med 12(8):2775. https:\/\/doi.org\/10.3390\/jcm12082775","journal-title":"J Clin Med"},{"key":"11453_CR399","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1275064","volume":"15","author":"S Wu","year":"2024","unstructured":"Wu S, Liu M, Zhang M, Ye X, Gu H, Jiang C, Zhu H, Ye X, Li Q, Huang X et al (2024) The gene expression of CALD1, CDH2, and POSTN in fibroblast are related to idiopathic pulmonary fibrosis. Front Immunol 15:1275064. https:\/\/doi.org\/10.3389\/fimmu.2024.1275064","journal-title":"Front Immunol"},{"issue":"22","key":"11453_CR400","doi-asserted-by":"publisher","first-page":"1990","DOI":"10.1212\/WNL.0000000000000476","volume":"82","author":"A Di Fonzo","year":"2014","unstructured":"Di Fonzo A, Ronchi D, Gallia F, Cribi\u00f9 FM, Trezzi I, Vetro A, Della Mina E, Limongelli I, Bellazzi R, Ricca I et al (2014) Lower motor neuron disease with respiratory failure caused by a novel MAPT mutation. Neurology 82(22):1990\u20131998. https:\/\/doi.org\/10.1212\/WNL.0000000000000476","journal-title":"Neurology"},{"issue":"1","key":"11453_CR401","doi-asserted-by":"publisher","DOI":"10.1186\/1476-9255-10-31","volume":"10","author":"Q Jin","year":"2013","unstructured":"Jin Q, Chen Y, Lou Y, He X (2013) Low serum retinol-binding protein-4 levels in acute exacerbations of chronic obstructive pulmonary disease at intensive care unit admission is a predictor of mortality in elderly patients. J Inflamm 10(1):31. https:\/\/doi.org\/10.1186\/1476-9255-10-31","journal-title":"J Inflamm"},{"issue":"1","key":"11453_CR402","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1186\/s12967-025-06116-y","volume":"23","author":"Y Zhao","year":"2025","unstructured":"Zhao Y, Patel J, Fan J, Wang X, Chen L, Li Y, Luo Z (2025) Integrated analysis reveals that EGR1 promotes epithelial IL33 production in T2 asthma. J Transl Med 23(1):203. https:\/\/doi.org\/10.1186\/s12967-025-06116-y","journal-title":"J Transl Med"},{"issue":"1","key":"11453_CR403","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1186\/s12967-024-05698-3","volume":"22","author":"M Tu","year":"2024","unstructured":"Tu M, Lu C, Jia H, Chen S, Wang Y, Li J, Cheng J, Yang M, Zhang G (2024) SULF1 expression is increased and promotes fibrosis through the TGF-\u03b21\/SMAD pathway in idiopathic pulmonary fibrosis. J Transl Med 22(1):885. https:\/\/doi.org\/10.1186\/s12967-024-05698-3","journal-title":"J Transl Med"},{"issue":"6","key":"11453_CR404","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1136\/thx.2008.107946","volume":"64","author":"N Oikonomou","year":"2009","unstructured":"Oikonomou N, Thanasopoulou A, Tzouvelekis A, Harokopos V, Paparountas T, Nikitopoulou I, Witke W, Karameris A, Kotanidou A, Bouros D et al (2009) Gelsolin expression is necessary for the development of modelled pulmonary inflammation and fibrosis. Thorax 64(6):467\u2013475. https:\/\/doi.org\/10.1136\/thx.2008.107946","journal-title":"Thorax"},{"issue":"6","key":"11453_CR405","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1165\/rcmb.2021-0542OC","volume":"67","author":"J Itano","year":"2022","unstructured":"Itano J, Taniguchi A, Senoo S, Asada N, Gion Y, Egusa Y, Guo L, Oda N, Araki K, Sato Y et al (2022) Neuropeptide Y antagonizes development of pulmonary fibrosis through IL-1\u03b2 inhibition. Am J Respir Cell Mol Biol 67(6):654\u2013665. https:\/\/doi.org\/10.1165\/rcmb.2021-0542OC","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"7","key":"11453_CR406","doi-asserted-by":"publisher","first-page":"289","DOI":"10.2131\/jts.49.289","volume":"49","author":"D Zhong","year":"2024","unstructured":"Zhong D, Luo C, Wang N, Lin J (2024) MiR-98-3p alleviates lipopolysaccharide-induced pulmonary microvascular endothelial barrier dysfunction by targeting DKK3 in sepsis-induced acute lung injury. J Toxicol Sci 49(7):289\u2013299. https:\/\/doi.org\/10.2131\/jts.49.289","journal-title":"J Toxicol Sci"},{"issue":"2","key":"11453_CR407","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1016\/j.yexcr.2017.11.038","volume":"362","author":"W Shen","year":"2018","unstructured":"Shen W, Liu J, Fan M, Wang S, Zhang Y, Wen L, Wang R, Wei W, Li N, Zhang Y et al (2018) MiR-3202 protects smokers from chronic obstructive pulmonary disease through inhibiting FAIM2: an in vivo and in vitro study. Exp Cell Res 362(2):370\u2013377. https:\/\/doi.org\/10.1016\/j.yexcr.2017.11.038","journal-title":"Exp Cell Res"},{"issue":"4","key":"11453_CR408","doi-asserted-by":"publisher","first-page":"426","DOI":"10.25122\/jml-2019-0108","volume":"12","author":"M Marushchak","year":"2019","unstructured":"Marushchak M, Maksiv K, Krynytska I, Dutchak O, Behosh N (2019) The severity of oxidative stress in comorbid chronic obstructive pulmonary disease (COPD) and hypertension: does it depend on ACE and AGT gene polymorphisms? J Med Life 12(4):426\u2013434. https:\/\/doi.org\/10.25122\/jml-2019-0108","journal-title":"J Med Life"},{"issue":"1","key":"11453_CR409","doi-asserted-by":"publisher","DOI":"10.1186\/s13062-024-00557-z","volume":"19","author":"H Wang","year":"2024","unstructured":"Wang H, Zhang L, Shang Y (2024) DEPTOR attenuates asthma progression by suppressing endoplasmic reticulum stress through SOD1. Biol Direct 19(1):114. https:\/\/doi.org\/10.1186\/s13062-024-00557-z","journal-title":"Biol Direct"},{"issue":"7","key":"11453_CR410","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2025.112973","volume":"28","author":"CSL Kong","year":"2025","unstructured":"Kong CSL, V M, Pantale\u00f3n-Garc\u00eda J, Evans SE, Chen J (2025) Truncated NTRK2 is induced in CAP1 endothelial cells during mouse lung injury-repair. iScience 28(7):112973. https:\/\/doi.org\/10.1016\/j.isci.2025.112973","journal-title":"iScience"},{"issue":"2","key":"11453_CR411","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/s0049-3848(00)00237-1","volume":"99","author":"M Fujii","year":"2000","unstructured":"Fujii M, Hayakawa H, Urano T, Sato A, Chida K, Nakamura H, Takada A (2000) Relevance of tissue factor and tissue factor pathway inhibitor for hypercoagulable state in the lungs of patients with idiopathic pulmonary fibrosis. Thromb Res 99(2):111\u2013117. https:\/\/doi.org\/10.1016\/s0049-3848(00)00237-1","journal-title":"Thromb Res"},{"issue":"1","key":"11453_CR412","doi-asserted-by":"publisher","DOI":"10.1186\/s12890-023-02360-4","volume":"23","author":"F Ding","year":"2023","unstructured":"Ding F, Yang L, Wang Y, Wang J, Ma Y, Jin J (2023) Serum Rcn3 level is a potential diagnostic biomarker for connective tissue disease-associated interstitial lung disease and reflects the severity of pulmonary function. BMC Pulm Med 23(1):68. https:\/\/doi.org\/10.1186\/s12890-023-02360-4","journal-title":"BMC Pulm Med"},{"issue":"6","key":"11453_CR413","doi-asserted-by":"publisher","first-page":"4632","DOI":"10.3892\/etm.2018.6746","volume":"16","author":"J Meng","year":"2018","unstructured":"Meng J, Zou Y, Chen J, Qin F, Chen X, Chen X, Dai S (2018) TLR4\/sMD-2 complex alleviates LPS-induced acute lung injury by inhibiting pro-inflammatory cytokines and chemokine CXCL1 expression. Exp Ther Med 16(6):4632\u20134638. https:\/\/doi.org\/10.3892\/etm.2018.6746","journal-title":"Exp Ther Med"},{"issue":"9","key":"11453_CR414","doi-asserted-by":"publisher","first-page":"1668","DOI":"10.21037\/tp-23-194","volume":"12","author":"A Asfari","year":"2023","unstructured":"Asfari A, Doyle EA, Jay GD, Aristizabal N, Manchikalapati A, Rahman AKMF, Hock KM, Borasino S, Ambalavanan N, Schmidt TA et al (2023) Plasma proteoglycan 4: a novel biomarker for acute lung injury after pediatric cardiac surgery. Transl Pediatr 12(9):1668\u20131675. https:\/\/doi.org\/10.21037\/tp-23-194","journal-title":"Transl Pediatr"},{"key":"11453_CR415","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1016\/j.ebiom.2019.03.054","volume":"43","author":"C Ballester-L\u00f3pez","year":"2019","unstructured":"Ballester-L\u00f3pez C, Conlon TM, Ert\u00fcz Z, Greiffo FR, Irmler M, Verleden SE, Beckers J, Fernandez IE, Eickelberg O, Yildirim A\u00d6 (2019) The Notch ligand DNER regulates macrophage IFN\u03b3 release in chronic obstructive pulmonary disease. EBioMedicine 43:562\u2013575. https:\/\/doi.org\/10.1016\/j.ebiom.2019.03.054","journal-title":"EBioMedicine"},{"key":"11453_CR416","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpet.2024.100045","author":"P Montuschi","year":"2025","unstructured":"Montuschi P, Adcock IM (2025) Protein tyrosine phosphatase 4A3 inhibition: a new pharmacological strategy for acute lung injury? J Pharmacol Exp Ther. https:\/\/doi.org\/10.1016\/j.jpet.2024.100045","journal-title":"J Pharmacol Exp Ther"},{"issue":"3","key":"11453_CR417","doi-asserted-by":"publisher","DOI":"10.3390\/nu15030586","volume":"15","author":"X Jiang","year":"2023","unstructured":"Jiang X, Yang Q, Qu H, Chen Y, Zhu S (2023) Endogenous n-3 PUFAs improve non-alcoholic fatty liver disease through FFAR4-mediated gut-liver crosstalk. Nutrients 15(3):586. https:\/\/doi.org\/10.3390\/nu15030586","journal-title":"Nutrients"},{"issue":"1","key":"11453_CR418","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-93778-9","volume":"15","author":"N Chen","year":"2025","unstructured":"Chen N, Luo P, Tang Y, Liu P, Wang J, Fan Y, Han L, Wang K (2025) Accelerators of chronic hepatitis B fibrosis cirrhosis CCND1 gene expression and promoter hypomethylation. Sci Rep 15(1):10630. https:\/\/doi.org\/10.1038\/s41598-025-93778-9","journal-title":"Sci Rep"},{"issue":"10","key":"11453_CR419","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1097\/CM9.0000000000002135","volume":"135","author":"H Huang","year":"2022","unstructured":"Huang H, Xu C (2022) Retinol-binding protein-4 and nonalcoholic fatty liver disease. Chin Med J (Engl) 135(10):1182\u20131189. https:\/\/doi.org\/10.1097\/CM9.0000000000002135","journal-title":"Chin Med J (Engl)"},{"key":"11453_CR420","doi-asserted-by":"publisher","DOI":"10.34133\/research.0577","volume":"8","author":"W Zhang","year":"2025","unstructured":"Zhang W, Guo J, Miao G, Chen J, Xu Y, Lai P, Zhang L, Han Y, Lam SM, Shui G et al (2025) Fat-1 ameliorates metabolic dysfunction-associated fatty liver disease and atherosclerosis through promoting the nuclear localization of PPAR\u03b1 in hamsters. Research 8:0577. https:\/\/doi.org\/10.34133\/research.0577","journal-title":"Research"},{"key":"11453_CR421","doi-asserted-by":"publisher","first-page":"1639","DOI":"10.2147\/JIR.S499396","volume":"18","author":"X Wu","year":"2025","unstructured":"Wu X, Pan T, Fang Z, Hui T, Yu X, Liu C, Guo Z, Liu C (2025) Identification of EGR1 as a key diagnostic biomarker in metabolic dysfunction-associated steatotic liver disease (MASLD) through machine learning and immune analysis. J Inflamm Res 18:1639\u20131656. https:\/\/doi.org\/10.2147\/JIR.S499396","journal-title":"J Inflamm Res"},{"issue":"1","key":"11453_CR422","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1007\/s00418-016-1425-8","volume":"146","author":"K Graham","year":"2016","unstructured":"Graham K, Murphy JI, Dhoot GK (2016) SULF1\/SULF2 reactivation during liver damage and tumour growth. Histochem Cell Biol 146(1):85\u201397. https:\/\/doi.org\/10.1007\/s00418-016-1425-8","journal-title":"Histochem Cell Biol"},{"issue":"3","key":"11453_CR423","doi-asserted-by":"publisher","first-page":"778","DOI":"10.2353\/ajpath.2006.050323","volume":"168","author":"L Leifeld","year":"2006","unstructured":"Leifeld L, Fink K, Debska G, Fielenbach M, Schmitz V, Sauerbruch T, Spengler U (2006) Anti-apoptotic function of gelsolin in fas antibody-induced liver failure in vivo. Am J Pathol 168(3):778\u2013785. https:\/\/doi.org\/10.2353\/ajpath.2006.050323","journal-title":"Am J Pathol"},{"issue":"2","key":"11453_CR424","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2023.112059","volume":"42","author":"C Ortiz","year":"2023","unstructured":"Ortiz C, Klein S, Reul WH, Magdaleno F, Gr\u00f6schl S, Dietrich P, Schierwagen R, Uschner FE, Torres S, Hieber C et al (2023) Neprilysin-dependent neuropeptide Y cleavage in the liver promotes fibrosis by blocking NPY-receptor 1. Cell Rep 42(2):112059. https:\/\/doi.org\/10.1016\/j.celrep.2023.112059","journal-title":"Cell Rep"},{"issue":"6","key":"11453_CR425","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmgh.2024.101406","volume":"18","author":"X Ding","year":"2024","unstructured":"Ding X, Zhang X, Cao J, Chen S, Chen Y, Yuan K, Chen B, Yang G, Li S, Yang J et al (2024) Sphingosine kinase 1 aggravates liver fibrosis by mediating macrophage recruitment and polarization. Cell Mol Gastroenterol Hepatol 18(6):101406. https:\/\/doi.org\/10.1016\/j.jcmgh.2024.101406","journal-title":"Cell Mol Gastroenterol Hepatol"},{"key":"11453_CR426","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.95185","volume":"13","author":"P Horn","year":"2024","unstructured":"Horn P, Norlin J, Almholt K, Viuff BM, Galsgaard ED, Hald A, Zosel F, Demuth H, Poulsen S, Norby PL et al (2024) Evaluation of Gremlin-1 as a therapeutic target in metabolic dysfunction-associated steatohepatitis. Elife 13:RP95185. https:\/\/doi.org\/10.7554\/eLife.95185","journal-title":"Elife"},{"key":"11453_CR427","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2025.156275","volume":"169","author":"Z Che","year":"2025","unstructured":"Che Z, Cai M, Dong X, Yuan Y, Wang Y, Xiao L, Song Y, Zhong J, Luo P, Wang H et al (2025) Angiotensinogen inhibition concurrently mitigates alcohol-associated hepatic and muscle injury. Metabolism 169:156275. https:\/\/doi.org\/10.1016\/j.metabol.2025.156275","journal-title":"Metabolism"},{"issue":"2","key":"11453_CR428","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1002\/hep.29849","volume":"68","author":"H Chen","year":"2018","unstructured":"Chen H, Shen F, Sherban A, Nocon A, Li Y, Wang H, Xu MJ, Rui X, Han J, Jiang B et al (2018) DEP domain-containing mTOR-interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute-on-chronic liver injury in alcoholic liver disease. Hepatology 68(2):496\u2013514. https:\/\/doi.org\/10.1002\/hep.29849","journal-title":"Hepatology"},{"issue":"7","key":"11453_CR429","doi-asserted-by":"publisher","first-page":"685","DOI":"10.14218\/JCTH.2024.00124","volume":"12","author":"A Gardin","year":"2024","unstructured":"Gardin A, Gaigne L, Mag\u00e9rus A, Rieux-Laucat F, Jacquemin E (2024) PLCG2 mutation in a patient presenting with type 2 autoimmune hepatitis. J Clin Transl Hepatol 12(7):685\u2013687. https:\/\/doi.org\/10.14218\/JCTH.2024.00124","journal-title":"J Clin Transl Hepatol"},{"key":"11453_CR430","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1016\/j.freeradbiomed.2025.06.022","volume":"237","author":"L Liu","year":"2025","unstructured":"Liu L, Qian S, Li W, Dong S, Ya R, He Y, Huang H, Chen Y, Ma N, Hao Y et al (2025) Hepatic I\u03bab\u03b6 promotes alcohol-associated liver disease and acute hepatitis by enhancing CXCL1-mediated neutrophil infiltration. Free Radic Biol Med 237:558\u2013569. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2025.06.022","journal-title":"Free Radic Biol Med"},{"issue":"2","key":"11453_CR431","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1016\/j.bbadis.2018.11.009","volume":"1865","author":"JE Nahon","year":"2019","unstructured":"Nahon JE, Hoekstra M, van Harmelen V, Rensen PCN, van Willems Dijk K, Kooijman S, Van Eck M (2019) Proteoglycan 4 deficiency protects against glucose intolerance and fatty liver disease in diet-induced obese mice. Biochim Biophys Acta Mol Basis Dis (Basel) 1865(2):494\u2013501. https:\/\/doi.org\/10.1016\/j.bbadis.2018.11.009","journal-title":"Biochim Biophys Acta Mol Basis Dis (Basel)"},{"issue":"1","key":"11453_CR432","doi-asserted-by":"publisher","DOI":"10.1097\/HC9.0000000000000623","volume":"9","author":"Y Liu","year":"2025","unstructured":"Liu Y, Yin W (2025) CD36 in liver diseases. Hepatol Commun 9(1):e0623. https:\/\/doi.org\/10.1097\/HC9.0000000000000623","journal-title":"Hepatol Commun"},{"issue":"3","key":"11453_CR433","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1089\/gtmb.2018.0203","volume":"23","author":"P Zhu","year":"2019","unstructured":"Zhu P, Lu H, Jing Y, Zhou H, Ding Y, Wang J, Guo D, Guo Z, Dong C (2019) Interaction between AGTR1 and PPAR\u03b3 gene polymorphisms on the risk of nonalcoholic fatty liver disease. Genet Test Mol Biomarkers 23(3):166\u2013175. https:\/\/doi.org\/10.1089\/gtmb.2018.0203","journal-title":"Genet Test Mol Biomarkers"},{"issue":"7","key":"11453_CR434","doi-asserted-by":"publisher","first-page":"1624","DOI":"10.1111\/liv.15905","volume":"44","author":"P Luo","year":"2024","unstructured":"Luo P, Yu X (2024) ENPP2\/autotaxin: the potential drug target for alcoholic liver disease identified through Mendelian randomization analysis. Liver Int 44(7):1624\u20131633. https:\/\/doi.org\/10.1111\/liv.15905","journal-title":"Liver Int"},{"issue":"13","key":"11453_CR435","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241310969","volume":"24","author":"J Krzistetzko","year":"2023","unstructured":"Krzistetzko J, G\u00e9raud C, Dormann C, Riedel A, Leibing T (2023) Association of differentially altered liver fibrosis with deposition of TGFBi in stabilin-deficient mice. Int J Mol Sci 24(13):10969. https:\/\/doi.org\/10.3390\/ijms241310969","journal-title":"Int J Mol Sci"},{"key":"11453_CR436","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.113929","volume":"147","author":"JY Cheng","year":"2025","unstructured":"Cheng JY, Shan GY, Wan H, Zhang YX, Gao ZC, Shi YP, Liu F, Yan WQ, Li HJ (2025) MIF\/CD74 axis in hepatic stellate cells mediates HBV-related liver fibrosis. Int Immunopharmacol 147:113929. https:\/\/doi.org\/10.1016\/j.intimp.2024.113929","journal-title":"Int Immunopharmacol"},{"key":"11453_CR437","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2018.07.032","volume":"124","author":"EK Mafanda","year":"2019","unstructured":"Mafanda EK, Kandhi R, Bobbala D, Khan MGM, Nandi M, Menendez A, Ramanathan S, Ilangumaran S (2019) Essential role of suppressor of cytokine signaling 1 (SOCS1) in hepatocytes and macrophages in the regulation of liver fibrosis. Cytokine 124:154501. https:\/\/doi.org\/10.1016\/j.cyto.2018.07.032","journal-title":"Cytokine"},{"issue":"1\u20132","key":"11453_CR438","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/j.jneuroim.2006.11.002","volume":"183","author":"S Cunningham","year":"2007","unstructured":"Cunningham S, O\u2019Doherty C, Patterson C, McDonnell G, Hawkins S, Marrosu MG, Vandenbroeck K (2007) The neuropeptide genes TAC1, TAC3, TAC4, VIP and PACAP(ADCYAP1), and susceptibility to multiple sclerosis. J Neuroimmunol 183(1\u20132):208\u2013213. https:\/\/doi.org\/10.1016\/j.jneuroim.2006.11.002","journal-title":"J Neuroimmunol"},{"issue":"7","key":"11453_CR439","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.3899\/jrheum.091285","volume":"37","author":"K Tsuzaka","year":"2010","unstructured":"Tsuzaka K, Itami Y, Takeuchi T, Shinozaki N, Morishita T (2010) ADAMTS5 is a biomarker for prediction of response to infliximab in patients with rheumatoid arthritis. J Rheumatol 37(7):1454\u20131460. https:\/\/doi.org\/10.3899\/jrheum.091285","journal-title":"J Rheumatol"},{"issue":"3","key":"11453_CR440","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1111\/j.1468-3083.2011.04413.x","volume":"27","author":"T Toyama","year":"2013","unstructured":"Toyama T, Asano Y, Takahashi T, Aozasa N, Akamata K, Noda S, Taniguchi T, Ichimura Y, Sumida H, Tamaki Z et al (2013) Clinical significance of serum retinol binding protein-4 levels in patients with systemic sclerosis. J Eur Acad Dermatol Venereol 27(3):337\u2013344. https:\/\/doi.org\/10.1111\/j.1468-3083.2011.04413.x","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"1","key":"11453_CR441","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.ymthe.2017.08.014","volume":"26","author":"C Amatya","year":"2018","unstructured":"Amatya C, Radichev IA, Ellefson J, Williams M, Savinov AY (2018) Self-transducible bimodal PDX1-FOXP3 protein lifts insulin secretion and curbs autoimmunity, boosting Tregs in type 1 diabetic mice. Mol Ther 26(1):184\u2013198. https:\/\/doi.org\/10.1016\/j.ymthe.2017.08.014","journal-title":"Mol Ther"},{"key":"11453_CR442","doi-asserted-by":"publisher","DOI":"10.34133\/research.0662","volume":"8","author":"L Yang","year":"2025","unstructured":"Yang L, Han X, Wang M, Zhang X, Wang L, Xu N, Wu H, Shi H, Pan W et al (2025) Early growth response gene 1 benefits autoimmune disease by promoting regulatory T cell differentiation as a regulator of Foxp3. Research 8:0662. https:\/\/doi.org\/10.34133\/research.0662","journal-title":"Research"},{"issue":"12","key":"11453_CR443","doi-asserted-by":"publisher","first-page":"1679","DOI":"10.1038\/s41418-024-01367-6","volume":"31","author":"J Lee","year":"2024","unstructured":"Lee J, Sasaki F, Koike E, Cho M, Lee Y, Dho SH, Lee J, Lee E, Toyohara E, Sunakawa M et al (2024) Gelsolin alleviates rheumatoid arthritis by negatively regulating NLRP3 inflammasome activation. Cell Death Differ 31(12):1679\u20131694. https:\/\/doi.org\/10.1038\/s41418-024-01367-6","journal-title":"Cell Death Differ"},{"issue":"7","key":"11453_CR444","doi-asserted-by":"publisher","first-page":"3451","DOI":"10.4049\/jimmunol.171.7.3451","volume":"171","author":"S Bedoui","year":"2003","unstructured":"Bedoui S, Miyake S, Lin Y, Miyamoto K, Oki S, Kawamura N, Beck-Sickinger A, von H\u00f6rsten S, Yamamura T (2003) Neuropeptide Y (NPY) suppresses experimental autoimmune encephalomyelitis: NPY1 receptor-specific inhibition of autoreactive Th1 responses in vivo. J Immunol 171(7):3451\u20133458. https:\/\/doi.org\/10.4049\/jimmunol.171.7.3451","journal-title":"J Immunol"},{"issue":"6","key":"11453_CR445","doi-asserted-by":"publisher","first-page":"2107","DOI":"10.1210\/jc.2006-2466","volume":"92","author":"NG Gavalas","year":"2007","unstructured":"Gavalas NG, Kemp EH, Krohn KJ, Brown EM, Watson PF, Weetman AP (2007) The calcium-sensing receptor is a target of autoantibodies in patients with autoimmune polyendocrine syndrome type 1. J Clin Endocrinol Metab 92(6):2107\u20132114. https:\/\/doi.org\/10.1210\/jc.2006-2466","journal-title":"J Clin Endocrinol Metab"},{"issue":"33","key":"11453_CR446","doi-asserted-by":"publisher","first-page":"28833","DOI":"10.1074\/jbc.M111.233932","volume":"286","author":"K Yan","year":"2011","unstructured":"Yan K, Cao Q, Reilly CM, Young NL, Garcia BA, Mishra N (2011) Histone deacetylase 9 deficiency protects against effector T cell-mediated systemic autoimmunity. J Biol Chem 286(33):28833\u201328843. https:\/\/doi.org\/10.1074\/jbc.M111.233932","journal-title":"J Biol Chem"},{"key":"11453_CR447","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2020.544658","volume":"11","author":"B Sawicka","year":"2020","unstructured":"Sawicka B, Borysewicz-Sa\u0144czyk H, Wawrusiewicz-Kurylonek N, Aversa T, Corica D, Go\u015bcik J, Kr\u0119towski A, Wa\u015bniewska M, Bossowski A (2020) Analysis of polymorphisms rs7093069-IL-2RA, rs7138803-FAIM2, and rs1748033-PADI4 in the group of adolescents with autoimmune thyroid diseases. Front Endocrinol (Lausanne) 11:544658. https:\/\/doi.org\/10.3389\/fendo.2020.544658","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"5","key":"11453_CR448","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1093\/intimm\/dxy021","volume":"30","author":"AM Szymanski","year":"2018","unstructured":"Szymanski AM, Ombrello MJ (2018) Using genes to triangulate the pathophysiology of granulomatous autoinflammatory disease: NOD2, PLCG2 and LACC1. Int Immunol 30(5):205\u2013213. https:\/\/doi.org\/10.1093\/intimm\/dxy021","journal-title":"Int Immunol"},{"issue":"1","key":"11453_CR449","doi-asserted-by":"publisher","DOI":"10.1186\/s12865-021-00469-x","volume":"22","author":"Y Zeng","year":"2021","unstructured":"Zeng Y, Lin Q, Yu L, Wang X, Lin Y, Zhang Y, Yan S, Lu X, Li Y, Li W et al (2021) Chemokine CXCL1 as a potential marker of disease activity in systemic lupus erythematosus. BMC Immunol 22(1):82. https:\/\/doi.org\/10.1186\/s12865-021-00469-x","journal-title":"BMC Immunol"},{"issue":"1","key":"11453_CR450","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-016-0626-3","volume":"13","author":"C Abad","year":"2016","unstructured":"Abad C, Jayaram B, Becquet L, Wang Y, O\u2019Dorisio MS, Waschek JA, Tan YV (2016) VPAC1 receptor (Vipr1)-deficient mice exhibit ameliorated experimental autoimmune encephalomyelitis, with specific deficits in the effector stage. J Neuroinflammation 13(1):169. https:\/\/doi.org\/10.1186\/s12974-016-0626-3","journal-title":"J Neuroinflammation"},{"key":"11453_CR451","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-015-0358-9","volume":"12","author":"S Jarius","year":"2015","unstructured":"Jarius S, Wildemann B (2015) \u201cMedusa head ataxia\u201d: the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 3: Anti-Yo\/CDR2, anti-Nb\/AP3B2, PCA-2, anti-Tr\/DNER, other antibodies, diagnostic pitfalls, summary and outlook. J Neuroinflammation 12:168. https:\/\/doi.org\/10.1186\/s12974-015-0358-9","journal-title":"J Neuroinflammation"},{"issue":"1","key":"11453_CR452","doi-asserted-by":"publisher","DOI":"10.1186\/s11658-024-00593-7","volume":"29","author":"C He","year":"2024","unstructured":"He C, Hua G, Liu Y, Li S (2024) Unveiling the hidden role of the interaction between CD36 and Fc\u03b3RIIb: implications for autoimmune disorders. Cell Mol Biol Lett 29(1):76. https:\/\/doi.org\/10.1186\/s11658-024-00593-7","journal-title":"Cell Mol Biol Lett"},{"issue":"92","key":"11453_CR453","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.adi9769","volume":"9","author":"C Wolf","year":"2024","unstructured":"Wolf C, Lim EL, Mokhtari M, Kind B, Odainic A, Lara-Villacanas E, Koss S, Mages S, Menzel K, Engel K et al (2024) UNC93B1 variants underlie TLR7-dependent autoimmunity. Sci Immunol 9(92):eadi9769. https:\/\/doi.org\/10.1126\/sciimmunol.adi9769","journal-title":"Sci Immunol"},{"issue":"3","key":"11453_CR454","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.97843","volume":"3","author":"MJ Rahman","year":"2018","unstructured":"Rahman MJ, Rodrigues KB, Quiel JA, Liu Y, Bhargava V, Zhao Y, Hotta-Iwamura C, Shih HY, Lau-Kilby AW, Malloy AM et al (2018) Restoration of the type I IFN-IL-1 balance through targeted blockade of PTGER4 inhibits autoimmunity in NOD mice. JCI Insight 3(3):e97843. https:\/\/doi.org\/10.1172\/jci.insight.97843","journal-title":"JCI Insight"},{"issue":"9","key":"11453_CR455","doi-asserted-by":"publisher","first-page":"4164","DOI":"10.4049\/jimmunol.1303118","volume":"192","author":"R Meza-Romero","year":"2014","unstructured":"Meza-Romero R, Benedek G, Yu X, Mooney JL, Dahan R, Duvshani N, Bucala R, Offner H, Reiter Y, Burrows GG et al (2014) HLA-DR\u03b11 constructs block CD74 expression and MIF effects in experimental autoimmune encephalomyelitis. J Immunol 192(9):4164\u20134173. https:\/\/doi.org\/10.4049\/jimmunol.1303118","journal-title":"J Immunol"},{"key":"11453_CR456","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.113013","volume":"141","author":"J Yu","year":"2024","unstructured":"Yu J, Mei J, Zuo D, Zhang M, Yu S, Li F, Wang J, Bi D, Ma S, Wang J et al (2024) Inflammatory factor-mediated miR-155\/SOCS1 signaling axis leads to Treg impairment in systemic lupus erythematosus. Int Immunopharmacol 141:113013. https:\/\/doi.org\/10.1016\/j.intimp.2024.113013","journal-title":"Int Immunopharmacol"},{"issue":"3","key":"11453_CR457","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1007\/s11626-021-00544-y","volume":"57","author":"JZ Wang","year":"2021","unstructured":"Wang JZ, Zhao BH (2021) MiR-23b-3p functions as a positive factor for osteoporosis progression by targeting CCND1 in MC3T3-E1 cells. In Vitro Cell Dev Biol Anim 57(3):324\u2013331. https:\/\/doi.org\/10.1007\/s11626-021-00544-y","journal-title":"In Vitro Cell Dev Biol Anim"},{"issue":"6","key":"11453_CR458","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1007\/s40520-019-01206-6","volume":"31","author":"G Mihai","year":"2019","unstructured":"Mihai G, Gasparik AI, Pascanu IM, Cevei M, Hutanu A, Pop RM (2019) The influence of visfatin, RBP-4 and insulin resistance on bone mineral density in women with treated primary osteoporosis. Aging Clin Exp Res 31(6):889\u2013895. https:\/\/doi.org\/10.1007\/s40520-019-01206-6","journal-title":"Aging Clin Exp Res"},{"issue":"5","key":"11453_CR459","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygeno.2023.110696","volume":"115","author":"C Wang","year":"2023","unstructured":"Wang C, Zhang X, Chen R, Zhu X, Lian N (2023) EGR1 mediates METTL3\/m6A\/CHI3L1 to promote osteoclastogenesis in osteoporosis. Genomics 115(5):110696. https:\/\/doi.org\/10.1016\/j.ygeno.2023.110696","journal-title":"Genomics"},{"issue":"33","key":"11453_CR460","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202303015","volume":"10","author":"Z Chen","year":"2023","unstructured":"Chen Z, Lv M, Liang J, Yang K, Li F, Zhou Z, Qiu M, Chen H, Cai Z, Cui W et al (2023) Neuropeptide Y-mediated gut microbiota alterations aggravate postmenopausal osteoporosis. Adv Sci Weinh 10(33):e2303015. https:\/\/doi.org\/10.1002\/advs.202303015","journal-title":"Adv Sci Weinh"},{"issue":"2","key":"11453_CR461","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1007\/s12020-017-1429-8","volume":"61","author":"A Di Nisio","year":"2018","unstructured":"Di Nisio A, Rocca MS, Ghezzi M, Ponce MR, Taglianetti S, Plebani M, Ferlin A, Foresta C (2018) Calcium-sensing receptor polymorphisms increase the risk of osteoporosis in ageing males. Endocrine 61(2):349\u2013352. https:\/\/doi.org\/10.1007\/s12020-017-1429-8","journal-title":"Endocrine"},{"issue":"5","key":"11453_CR462","doi-asserted-by":"publisher","DOI":"10.1093\/jbmrpl\/ziae051","volume":"8","author":"G Kaur","year":"2024","unstructured":"Kaur G, Pippin JA, Chang S, Redmond J, Chesi A, Wells AD, Maerz T, Grant SFA, Coleman RM, Hankenson KD et al (2024) Osteoporosis GWAS-implicated DNM3 locus contextually regulates osteoblastic and chondrogenic fate of mesenchymal stem\/progenitor cells through oscillating miR-199a-5p levels. JBMR Plus 8(5):ziae051. https:\/\/doi.org\/10.1093\/jbmrpl\/ziae051","journal-title":"JBMR Plus"},{"issue":"2","key":"11453_CR463","doi-asserted-by":"publisher","DOI":"10.1007\/s13577-025-01180-4","volume":"38","author":"O Krasnova","year":"2025","unstructured":"Krasnova O, Semenova P, Kovaleva A, Sopova J, Turilova V, Yakovleva T, Bystrova O, Martynova M, Neganova I (2025) Derivation of hiPSC line (ICADRB2i007-A-3) from an individual with osteoporosis linked to ADRB2: c.46G>A. Hum Cell 38(2):54. https:\/\/doi.org\/10.1007\/s13577-025-01180-4","journal-title":"Hum Cell"},{"key":"11453_CR464","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2024.156297","volume":"136","author":"F Wang","year":"2025","unstructured":"Wang F, Zhang F, Lin B, Xiao W, Wang X, Wang N (2025) Sarsasapogenin stimulates angiogenesis and osteogenesis coupling to treat estrogen deficiency-induced osteoporosis by activating the GPX4\/SLIT3\/ROBO1 axis. Phytomedicine 136:156297. https:\/\/doi.org\/10.1016\/j.phymed.2024.156297","journal-title":"Phytomedicine"},{"issue":"1","key":"11453_CR465","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1007\/s00223-025-01350-4","volume":"116","author":"Y Zhang","year":"2025","unstructured":"Zhang Y, Shi H, Dai X, Shen J, Yin J, Xu T, Yue G, Guo H, Liang R, Chen Q et al (2025) Semaphorin 3A on osteoporosis: an overreview of the literature. Calcif Tissue Int 116(1):43. https:\/\/doi.org\/10.1007\/s00223-025-01350-4","journal-title":"Calcif Tissue Int"},{"key":"11453_CR466","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.taap.2019.05.014","volume":"376","author":"L Wang","year":"2019","unstructured":"Wang L, Cheng L, Zhang B, Wang N, Wang F (2019) Tanshinone prevents alveolar bone loss in ovariectomized osteoporosis rats by up-regulating phosphoglycerate dehydrogenase. Toxicol Appl Pharmacol 376:9\u201316. https:\/\/doi.org\/10.1016\/j.taap.2019.05.014","journal-title":"Toxicol Appl Pharmacol"},{"issue":"1","key":"11453_CR467","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-018-0935-9","volume":"9","author":"S Chen","year":"2018","unstructured":"Chen S, Jia L, Zhang S, Zheng Y, Zhou Y (2018) DEPTOR regulates osteogenic differentiation via inhibiting MEG3-mediated activation of BMP4 signaling and is involved in osteoporosis. Stem Cell Res Ther 9(1):185. https:\/\/doi.org\/10.1186\/s13287-018-0935-9","journal-title":"Stem Cell Res Ther"},{"issue":"6","key":"11453_CR468","doi-asserted-by":"publisher","first-page":"4716","DOI":"10.3892\/mmr.2020.11543","volume":"22","author":"Y Hu","year":"2020","unstructured":"Hu Y, Wang L, Zhao Z, Lu W, Fan J, Gao B, Luo Z, Jie Q, Shi X, Yang L (2020) Cytokines CCL2 and CXCL1 may be potential novel predictors of early bone loss. Mol Med Rep 22(6):4716\u20134724. https:\/\/doi.org\/10.3892\/mmr.2020.11543","journal-title":"Mol Med Rep"},{"issue":"1","key":"11453_CR469","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1186\/s13075-025-03624-6","volume":"27","author":"YC Peng","year":"2025","unstructured":"Peng YC, Ye YS, Hu QX, Hao ZQ, Li ZY, Jiang LY, Peng HR, Liu RX, Zha ZG, Zhang HT (2025) Trim21 deficiency alleviates osteoporosis by inhibiting osteoclast differentiation through regulating Txnip. Arthritis Res Ther 27(1):163. https:\/\/doi.org\/10.1186\/s13075-025-03624-6","journal-title":"Arthritis Res Ther"},{"issue":"19","key":"11453_CR470","doi-asserted-by":"publisher","first-page":"8103","DOI":"10.18632\/aging.102279","volume":"11","author":"Y Jia","year":"2019","unstructured":"Jia Y, Jiang J, Zhao K, Zhang T, Sun P, Peng J, Yang Q, Qian Y (2019) Disulfiram suppressed ethanol promoted RANKL-induced osteoclastogenesis in vitro and ethanol-induced osteoporosis in vivo via ALDH1A1-NFATc1 axis. Aging (Albany NY) 11(19):8103\u20138119. https:\/\/doi.org\/10.18632\/aging.102279","journal-title":"Aging (Albany NY)"},{"key":"11453_CR471","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2021.120936","volume":"275","author":"L Batoon","year":"2021","unstructured":"Batoon L, Millard SM, Raggatt LJ, Sandrock C, Pickering E, Williams K, Sun LWH, Wu AC, Irvine KM, Pivonka P et al (2021) Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bones. Biomaterials 275:120936. https:\/\/doi.org\/10.1016\/j.biomaterials.2021.120936","journal-title":"Biomaterials"},{"issue":"14","key":"11453_CR472","doi-asserted-by":"publisher","first-page":"6634","DOI":"10.1111\/jcmm.16667","volume":"25","author":"M Sikora","year":"2021","unstructured":"Sikora M, \u015amieszek A, Marycz K (2021) Bone marrow stromal cells (BMSCs CD45- \/CD44+ \/CD73+ \/CD90+ ) isolated from osteoporotic mice SAM\/P6 as a novel model for osteoporosis investigation. J Cell Mol Med 25(14):6634\u20136651. https:\/\/doi.org\/10.1111\/jcmm.16667","journal-title":"J Cell Mol Med"},{"issue":"1","key":"11453_CR473","doi-asserted-by":"publisher","DOI":"10.1038\/s41420-024-01847-1","volume":"10","author":"H Xue","year":"2024","unstructured":"Xue H, Feng Z, Yuan P, Qiao L, Lou Q, Zhao X, Ma Q, Wang S, Shen Y, Ye H et al (2024) Restrained Mitf-associated autophagy by Mulberroside A ameliorates osteoclastogenesis and counteracts OVX-induced osteoporosis in mice. Cell Death Discov 10(1):80. https:\/\/doi.org\/10.1038\/s41420-024-01847-1","journal-title":"Cell Death Discov"},{"issue":"8","key":"11453_CR474","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1359\/jbmr.1997.12.8.1272","volume":"12","author":"T Sugimoto","year":"1997","unstructured":"Sugimoto T, Nishiyama K, Kuribayashi F, Chihara K (1997) Serum levels of insulin-like growth factor (IGF) I, IGF-binding protein (IGFBP)-2, and IGFBP-3 in osteoporotic patients with and without spinal fractures. J Bone Miner Res 12(8):1272\u20131279. https:\/\/doi.org\/10.1359\/jbmr.1997.12.8.1272","journal-title":"J Bone Miner Res"},{"issue":"3","key":"11453_CR475","doi-asserted-by":"publisher","DOI":"10.3390\/genes14030542","volume":"14","author":"B Gasperini","year":"2023","unstructured":"Gasperini B, Visconti VV, Ciccacci C, Falvino A, Gasbarra E, Iundusi R, Brandi ML, Botta A, Tarantino U (2023) Role of the Vitamin D Receptor (VDR) in the pathogenesis of osteoporosis: a genetic, epigenetic and molecular pilot study. Genes 14(3):542. https:\/\/doi.org\/10.3390\/genes14030542","journal-title":"Genes"},{"issue":"1","key":"11453_CR476","doi-asserted-by":"publisher","first-page":"6057","DOI":"10.1080\/21655979.2021.1967711","volume":"12","author":"J Yu","year":"2021","unstructured":"Yu J, Xiao M, Ren G (2021) Long non-coding RNA XIST promotes osteoporosis by inhibiting the differentiation of bone marrow mesenchymal stem cell by sponging miR-29b-3p that suppresses nicotinamide N-methyltransferase. Bioengineered 12(1):6057\u20136069. https:\/\/doi.org\/10.1080\/21655979.2021.1967711","journal-title":"Bioengineered"},{"issue":"1","key":"11453_CR477","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-024-03226-0","volume":"21","author":"L Luo","year":"2024","unstructured":"Luo L, Ma X, Kong D, Dai Y, Li T, Yu H, Liu J, Li M, Xu Y, Xiang G et al (2024) Multiomics integrated analysis and experimental validation identify TLR4 and ALOX5 as oxidative stress-related biomarkers in intracranial aneurysms. J Neuroinflammation 21(1):225. https:\/\/doi.org\/10.1186\/s12974-024-03226-0","journal-title":"J Neuroinflammation"},{"issue":"5","key":"11453_CR478","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2021.12433","volume":"24","author":"Z Zhong","year":"2021","unstructured":"Zhong Z, Su W, Chen H (2021) MicroRNA\u2011532\u20115p regulates oxidative stress and insulin secretion damage in high glucose\u2011induced pancreatic \u03b2 cells by downregulating the expression levels of CCND1. Mol Med Rep 24(5):793. https:\/\/doi.org\/10.3892\/mmr.2021.12433","journal-title":"Mol Med Rep"},{"issue":"5","key":"11453_CR479","doi-asserted-by":"publisher","DOI":"10.3390\/antiox13050508","volume":"13","author":"X Bradford","year":"2024","unstructured":"Bradford X, Fernandes HJR, Snowden SG (2024) Changes in oxidised phospholipids in response to oxidative stress in microtubule-associated protein tau (MAPT) mutant dopamine neurons. Antioxidants 13(5):508. https:\/\/doi.org\/10.3390\/antiox13050508","journal-title":"Antioxidants"},{"issue":"1","key":"11453_CR480","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1515\/tnsci-2022-0252","volume":"13","author":"Q Wang","year":"2022","unstructured":"Wang Q, Tian S, Xiao D, Zhao R, Zhang X, Dou Z, Li C, Ma Z (2022) Correlation of serum RBP4 level with oxidative stress and unstable carotid plaque in patients with cerebral infarction. Transl Neurosci 13(1):354\u2013360. https:\/\/doi.org\/10.1515\/tnsci-2022-0252","journal-title":"Transl Neurosci"},{"key":"11453_CR481","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.1011187","volume":"13","author":"S Baumel-Alterzon","year":"2022","unstructured":"Baumel-Alterzon S, Scott DK (2022) Regulation of Pdx1 by oxidative stress and Nrf2 in pancreatic beta-cells. Front Endocrinol (Lausanne) 13:1011187. https:\/\/doi.org\/10.3389\/fendo.2022.1011187","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"3","key":"11453_CR482","doi-asserted-by":"publisher","first-page":"767","DOI":"10.3390\/nu12030767","volume":"12","author":"KE Boyle","year":"2020","unstructured":"Boyle KE, Magill-Collins MJ, Newsom SA, Janssen RC, Friedman JE (2020) Maternal fat-1 transgene protects offspring from excess weight gain, oxidative stress, and reduced fatty acid oxidation in response to high-fat diet. Nutrients 12(3):767. https:\/\/doi.org\/10.3390\/nu12030767","journal-title":"Nutrients"},{"key":"11453_CR483","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2025.103498","volume":"80","author":"Y Pang","year":"2025","unstructured":"Pang Y, Gong S, Tetti M, Sun Z, Mir-Bashiri S, Bidlingmaier M, Kn\u00f6sel T, Wolf E, Reincke M, Kemter E et al (2025) EGR1 regulates oxidative stress and aldosterone production in adrenal cells and aldosterone-producing adenomas. Redox Biol 80:103498. https:\/\/doi.org\/10.1016\/j.redox.2025.103498","journal-title":"Redox Biol"},{"issue":"6","key":"11453_CR484","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1111\/j.1525-1594.2010.01154.x","volume":"35","author":"J Kuncov\u00e1","year":"2011","unstructured":"Kuncov\u00e1 J, S\u00fdkora R, Chvojka J, Sv\u00edglerov\u00e1 J, Stengl M, Krou\u017eeck\u00fd A, Nalos L, Mat\u011bjovi\u010d M (2011) Plasma and tissue levels of neuropeptide y in experimental septic shock: relation to hemodynamics, inflammation, oxidative stress, and hemofiltration. Artif Organs 35(6):625\u2013633. https:\/\/doi.org\/10.1111\/j.1525-1594.2010.01154.x","journal-title":"Artif Organs"},{"issue":"6","key":"11453_CR485","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.1016\/j.jid.2022.12.004","volume":"143","author":"S Muecklich","year":"2023","unstructured":"Muecklich S, Shehzad K, Tiemann J, Li L, Leson S, Nelson PJ, Jennemann R, Klein M, Becker C, Sandhoff R et al (2023) DKK3 promotes oxidative stress\u2012induced fibroblast activity. J Invest Dermatol 143(6):1088-1090.e2. https:\/\/doi.org\/10.1016\/j.jid.2022.12.004","journal-title":"J Invest Dermatol"},{"issue":"1\u20133","key":"11453_CR486","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1089\/ars.2023.0543","volume":"42","author":"LQ Lu","year":"2025","unstructured":"Lu LQ, Li MR, Liu XY, Peng D, Liu HR, Zhang XJ, Luo XJ, Peng J (2025) CARD11-BCL10-MALT1 complex-dependent MALT1 activation facilitates myocardial oxidative stress in doxorubicin-treated mice via enhancing k48-linked ubiquitination of Nrf2. Antioxid Redox Signal 42(1\u20133):115\u2013132. https:\/\/doi.org\/10.1089\/ars.2023.0543","journal-title":"Antioxid Redox Signal"},{"issue":"5","key":"11453_CR487","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1097\/MBC.0b013e3281a3bee9","volume":"18","author":"K Pawlak","year":"2007","unstructured":"Pawlak K, Pawlak D, Mysliwiec M (2007) Association between tissue factor, its pathway inhibitor and oxidative stress in peritoneal dialysis patients. Blood Coagul Fibrinolysis 18(5):467\u2013471. https:\/\/doi.org\/10.1097\/MBC.0b013e3281a3bee9","journal-title":"Blood Coagul Fibrinolysis"},{"key":"11453_CR488","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/6801587","volume":"2020","author":"X Hu","year":"2020","unstructured":"Hu X, Li S, Doycheva DM, Huang L, Lenahan C, Liu R, Huang J, Gao L, Tang J, Zuo G et al (2020) Rh-CSF1 attenuates oxidative stress and neuronal apoptosis via the CSF1R\/PLCG2\/PKA\/UCP2 signaling pathway in a rat model of neonatal HIE. Oxid Med Cell Longev 2020:6801587. https:\/\/doi.org\/10.1155\/2020\/6801587","journal-title":"Oxid Med Cell Longev"},{"key":"11453_CR489","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2024.111367","volume":"407","author":"X Jiang","year":"2025","unstructured":"Jiang X, Chen X, He L, Qin D, Nie M, Li C, Liu X (2025) Equol promotes osteogenic differentiation of hPDLSCs by inhibiting oxidative stress via IL1B\/NF-\u03baB\/CXCL1 signaling axis. Chem Biol Interact 407:111367. https:\/\/doi.org\/10.1016\/j.cbi.2024.111367","journal-title":"Chem Biol Interact"},{"issue":"1","key":"11453_CR490","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-018-0790-9","volume":"17","author":"J Liu","year":"2018","unstructured":"Liu J, Yang P, Zuo G, He S, Tan W, Zhang X, Su C, Zhao L, Wei L et al (2018) Long-chain fatty acid activates hepatocytes through CD36 mediated oxidative stress. Lipids Health Dis 17(1):153. https:\/\/doi.org\/10.1186\/s12944-018-0790-9","journal-title":"Lipids Health Dis"},{"issue":"4","key":"11453_CR491","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1080\/08037050903118706","volume":"18","author":"N Fenty-Stewart","year":"2009","unstructured":"Fenty-Stewart N, Park JY, Roth SM, Hagberg JM, Basu S, Ferrell RE, Brown MD (2009) Independent and combined influence of AGTR1 variants and aerobic exercise on oxidative stress in hypertensives. Blood Press 18(4):204\u2013212. https:\/\/doi.org\/10.1080\/08037050903118706","journal-title":"Blood Press"},{"issue":"3","key":"11453_CR492","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1007\/s12192-023-01324-1","volume":"28","author":"G Fang","year":"2023","unstructured":"Fang G, Shen Y, Liao D (2023) ENPP2 alleviates hypoxia\/reoxygenation injury and ferroptosis by regulating oxidative stress and mitochondrial function in human cardiac microvascular endothelial cells. Cell Stress Chaperones 28(3):253\u2013263. https:\/\/doi.org\/10.1007\/s12192-023-01324-1","journal-title":"Cell Stress Chaperones"},{"issue":"12","key":"11453_CR493","doi-asserted-by":"publisher","first-page":"2201","DOI":"10.1002\/glia.24606","volume":"72","author":"L Zhou","year":"2024","unstructured":"Zhou L, Wang N, Feng W, Liu X, Wu Q, Chen J, Jiao X, Ning X, Qi Z, Xu Z et al (2024) Soluble TGF-\u03b2 decoy receptor TGFBR3 exacerbates Alzheimer\u2019s disease pathology by modifying microglial function. Glia 72(12):2201\u20132216. https:\/\/doi.org\/10.1002\/glia.24606","journal-title":"Glia"},{"issue":"5\u20136","key":"11453_CR494","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1101\/gad.350211.122","volume":"37","author":"S Song","year":"2023","unstructured":"Song S, Su Z, Kon N, Chu B, Li H, Jiang X, Luo J, Stockwell BR, Gu W (2023) ALOX5-mediated ferroptosis acts as a distinct cell death pathway upon oxidative stress in Huntington\u2019s disease. Genes Dev 37(5\u20136):204\u2013217. https:\/\/doi.org\/10.1101\/gad.350211.122","journal-title":"Genes Dev"},{"key":"11453_CR495","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2021.105581","volume":"162","author":"P Dietrich","year":"2022","unstructured":"Dietrich P, Alli S, Mulligan MK, Cox R, Ashbrook DG, Williams RW, Dragatsis I (2022) Identification of cyclin D1 as a major modulator of 3-nitropropionic acid-induced striatal neurodegeneration. Neurobiol Dis 162:105581. https:\/\/doi.org\/10.1016\/j.nbd.2021.105581","journal-title":"Neurobiol Dis"},{"issue":"1","key":"11453_CR496","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.molbrainres.2004.09.008","volume":"133","author":"RF Miguel","year":"2005","unstructured":"Miguel RF, Pollak A, Lubec G (2005) Metalloproteinase ADAMTS-1 but not ADAMTS-5 is manifold overexpressed in neurodegenerative disorders as Down syndrome, Alzheimer\u2019s and Pick\u2019s disease. Brain Res Mol Brain Res 133(1):1\u20135. https:\/\/doi.org\/10.1016\/j.molbrainres.2004.09.008","journal-title":"Brain Res Mol Brain Res"},{"issue":"7","key":"11453_CR497","doi-asserted-by":"publisher","first-page":"4893","DOI":"10.1007\/s12035-015-9415-8","volume":"53","author":"CC Zhang","year":"2016","unstructured":"Zhang CC, Xing A, Tan MS, Tan L, Yu JT (2016) The role of MAPT in neurodegenerative diseases: genetics, mechanisms and therapy. Mol Neurobiol 53(7):4893\u20134904. https:\/\/doi.org\/10.1007\/s12035-015-9415-8","journal-title":"Mol Neurobiol"},{"issue":"1","key":"11453_CR498","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-025-03373-9","volume":"15","author":"C Wei","year":"2025","unstructured":"Wei C, Zhang G, Fu X, Zhao M, Zhai W, Shen Y, Sun L (2025) Correlation of peripheral olfactomedin 1 with Alzheimer\u2019s disease and cognitive functions. Transl Psychiatry 15(1):146. https:\/\/doi.org\/10.1038\/s41398-025-03373-9","journal-title":"Transl Psychiatry"},{"key":"11453_CR499","doi-asserted-by":"publisher","DOI":"10.1038\/srep29396","volume":"6","author":"C Guo","year":"2016","unstructured":"Guo C, Zhang S, Li JY, Ding C, Yang ZH, Chai R, Wang X, Wang ZY (2016) Chronic hyperglycemia induced via the heterozygous knockout of Pdx1 worsens neuropathological lesion in an Alzheimer mouse model. Sci Rep 6:29396. https:\/\/doi.org\/10.1038\/srep29396","journal-title":"Sci Rep"},{"issue":"1","key":"11453_CR500","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1002\/mds.27536","volume":"34","author":"M Le\u0144ska-Mieciek","year":"2019","unstructured":"Le\u0144ska-Mieciek M, Charzewska A, Kr\u00f3licki L, Hoffman-Zacharska D, Chen ZS, Lau KF, Chan HYE, Gambin T, Fiszer U (2019) Familial ataxia, tremor, and dementia in a polish family with a novel mutation in the CCDC88C gene. Mov Disord 34(1):142\u2013144. https:\/\/doi.org\/10.1002\/mds.27536","journal-title":"Mov Disord"},{"issue":"11","key":"11453_CR501","doi-asserted-by":"publisher","first-page":"1981","DOI":"10.1021\/acschemneuro.2c00724","volume":"14","author":"S Guo","year":"2023","unstructured":"Guo S, Gao Y, Zhao Y (2023) Neuroprotective microRNA-381 binds to repressed early growth response 1 (EGR1) and alleviates oxidative stress injury in Parkinson\u2019s disease. ACS Chem Neurosci 14(11):1981\u20131991. https:\/\/doi.org\/10.1021\/acschemneuro.2c00724","journal-title":"ACS Chem Neurosci"},{"key":"11453_CR502","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2024.126938","volume":"282","author":"L Ma","year":"2025","unstructured":"Ma L, Meng T, Wang Y, Xue Y, Zheng Y, Chen J, Xu D, Sun J, Yang F, Huang J et al (2025) Real-time analysis of the biomolecular interaction between gelsolin and A\u03b21-42 monomer and its implication for Alzheimer\u2019s disease. Talanta 282:126938. https:\/\/doi.org\/10.1016\/j.talanta.2024.126938","journal-title":"Talanta"},{"issue":"5","key":"11453_CR503","doi-asserted-by":"publisher","first-page":"848","DOI":"10.1111\/jnc.13847","volume":"139","author":"D Komnig","year":"2016","unstructured":"Komnig D, Schulz JB, Reich A, Falkenburger BH (2016) Mice lacking Faim2 show increased cell death in the MPTP mouse model of Parkinson disease. J Neurochem 139(5):848\u2013857. https:\/\/doi.org\/10.1111\/jnc.13847","journal-title":"J Neurochem"},{"issue":"24","key":"11453_CR504","doi-asserted-by":"publisher","DOI":"10.3390\/ijms242417210","volume":"24","author":"AM Tom\u00e1s","year":"2023","unstructured":"Tom\u00e1s AM, Bento-Torres NVO, Jardim NYV, Moraes PM, da Costa VO, Modesto AC, Khayat AS, Bento-Torres J, Pican\u00e7o-Diniz CW (2023) Risk polymorphisms of FNDC5, BDNF, and NTRK2 and poor education interact and aggravate age-related cognitive decline. Int J Mol Sci 24(24):17210. https:\/\/doi.org\/10.3390\/ijms242417210","journal-title":"Int J Mol Sci"},{"issue":"2","key":"11453_CR505","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1016\/j.neurobiolaging.2010.02.016","volume":"33","author":"F Piazza","year":"2012","unstructured":"Piazza F, Galimberti G, Conti E, Isella V, Perlangeli MV, Speranza T, Borroni B, Pogliani EM, Padovani A, Ferrarese C (2012) Increased tissue factor pathway inhibitor and homocysteine in Alzheimer\u2019s disease. Neurobiol Aging 33(2):226\u2013233. https:\/\/doi.org\/10.1016\/j.neurobiolaging.2010.02.016","journal-title":"Neurobiol Aging"},{"issue":"5","key":"11453_CR506","doi-asserted-by":"publisher","DOI":"10.1002\/alz.70231","volume":"21","author":"EJ Messenger","year":"2025","unstructured":"Messenger EJ, Baar SA, Bedford LM, Tsai AP, Lin PB, Ferguson CA, Xu G, Wallace A, Landreth GE, Lamb BT et al (2025) PLCG2 modulates TREM2 expression and signaling in response to Alzheimer\u2019s disease pathology. Alzheimers Dement 21(5):e70231. https:\/\/doi.org\/10.1002\/alz.70231","journal-title":"Alzheimers Dement"},{"issue":"2","key":"11453_CR507","doi-asserted-by":"publisher","first-page":"266","DOI":"10.4103\/1673-5374.317960","volume":"17","author":"RF Marques","year":"2022","unstructured":"Marques RF, Duncan KE (2022) SYNGR4 and PLEKHB1 deregulation in motor neurons of amyotrophic lateral sclerosis models: potential contributions to pathobiology. Neural Regen Res 17(2):266\u2013270. https:\/\/doi.org\/10.4103\/1673-5374.317960","journal-title":"Neural Regen Res"},{"issue":"1","key":"11453_CR508","doi-asserted-by":"publisher","first-page":"225","DOI":"10.24272\/j.issn.2095-8137.2024.228","volume":"46","author":"XZ Ma","year":"2025","unstructured":"Ma XZ, Jia GR, Li MY, Zhang SH, Wang ZX, Song N, Liu YJ, Xie JX (2025) Elevated CXCL1 triggers dopaminergic neuronal loss in the substantia nigra of C57BL\/6J mice: evaluation of a novel Parkinsonian mouse model. Zool Res 46(1):225\u2013235. https:\/\/doi.org\/10.24272\/j.issn.2095-8137.2024.228","journal-title":"Zool Res"},{"key":"11453_CR509","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.biochi.2017.01.009","volume":"135","author":"O \u0160er\u00fd","year":"2017","unstructured":"\u0160er\u00fd O, Janoutov\u00e1 J, Ewerlingov\u00e1 L, H\u00e1lov\u00e1 A, Lochman J, Janout V, Khan NA, Balcar VJ (2017) CD36 gene polymorphism is associated with Alzheimer\u2019s disease. Biochimie 135:46\u201353. https:\/\/doi.org\/10.1016\/j.biochi.2017.01.009","journal-title":"Biochimie"},{"key":"11453_CR510","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1326-3-13","volume":"3","author":"KJ Bryan","year":"2008","unstructured":"Bryan KJ, Zhu X, Harris PL, Perry G, Castellani RJ, Smith MA, Casadesus G (2008) Expression of CD74 is increased in neurofibrillary tangles in Alzheimer\u2019s disease. Mol Neurodegener 3:13. https:\/\/doi.org\/10.1186\/1750-1326-3-13","journal-title":"Mol Neurodegener"},{"issue":"3","key":"11453_CR511","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1177\/1753425913488429","volume":"20","author":"DD Lofrumento","year":"2014","unstructured":"Lofrumento DD, Nicolardi G, Cianciulli A, De Nuccio F, La Pesa V, Carofiglio V, Dragone T, Calvello R, Panaro MA (2014) Neuroprotective effects of resveratrol in an MPTP mouse model of Parkinson\u2019s-like disease: possible role of SOCS-1 in reducing pro-inflammatory responses. Innate Immun 20(3):249\u2013260. https:\/\/doi.org\/10.1177\/1753425913488429","journal-title":"Innate Immun"},{"issue":"1","key":"11453_CR512","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1007\/s11033-019-05119-5","volume":"47","author":"M Calabr\u00f2","year":"2020","unstructured":"Calabr\u00f2 M, Mandelli L, Crisafulli C, Porcelli S, Albani D, Politis A, Papadimitriou GN, Di Nicola M, Janiri L, Colombo R et al (2020) Psychiatric disorders and SLC6A4 gene variants: possible effects on alcohol dependence and alzheimer\u2019s disease. Mol Biol Rep 47(1):191\u2013200. https:\/\/doi.org\/10.1007\/s11033-019-05119-5","journal-title":"Mol Biol Rep"},{"issue":"9","key":"11453_CR513","doi-asserted-by":"publisher","first-page":"3748","DOI":"10.4103\/jfmpc.jfmpc_57_24","volume":"13","author":"AG Jadhao","year":"2024","unstructured":"Jadhao AG, Gaikwad KB, Yadav RR (2024) Serum retinol binding protein 4 in individuals with essential hypertension and type 2 diabetes: a cross-sectional study. J Family Med Prim Care 13(9):3748\u20133752. https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_57_24","journal-title":"J Family Med Prim Care"},{"issue":"5","key":"11453_CR514","doi-asserted-by":"publisher","DOI":"10.3390\/biology11050677","volume":"11","author":"M Laggner","year":"2022","unstructured":"Laggner M, Oberndorfer F, Golabi B, Bauer J, Zuckermann A, Hacker P, Lang I, Skoro-Sajer N, Gerges C, Taghavi S et al (2022) EGR1 is implicated in right ventricular cardiac remodeling associated with pulmonary hypertension. Biology 11(5):677. https:\/\/doi.org\/10.3390\/biology11050677","journal-title":"Biology"},{"issue":"1","key":"11453_CR515","first-page":"48","volume":"1","author":"M Baltazi","year":"2011","unstructured":"Baltazi M, Katsiki N, Savopoulos C, Iliadis F, Koliakos G, Hatzitolios AI (2011) Plasma neuropeptide Y (NPY) and alpha-melanocyte stimulating hormone (a-MSH) levels in patients with or without hypertension and\/or obesity: a pilot study. Am J Cardiovasc Dis 1(1):48\u201359","journal-title":"Am J Cardiovasc Dis"},{"issue":"3","key":"11453_CR516","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12031034","volume":"12","author":"AC Sch\u00e4fer","year":"2023","unstructured":"Sch\u00e4fer AC, Pieper D, Dihazi H, Dihazi GH, L\u00fcders S, Koziolek MJ, Wallbach M (2023) Urinary Dickkopf-3 (DKK3) is associated with greater eGFR loss in patients with resistant hypertension. J Clin Med 12(3):1034. https:\/\/doi.org\/10.3390\/jcm12031034","journal-title":"J Clin Med"},{"issue":"7","key":"11453_CR517","doi-asserted-by":"publisher","first-page":"1348","DOI":"10.1161\/HYPERTENSIONAHA.121.18399","volume":"79","author":"B Liu","year":"2022","unstructured":"Liu B, Wei YP, Fan X, Hu X, Chen Z, Liu X, Xu Y, Wang L, Wang T, Ruiz M et al (2022) Calcium sensing receptor variants increase pulmonary hypertension susceptibility. Hypertension 79(7):1348\u20131360. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.121.18399","journal-title":"Hypertension"},{"issue":"22","key":"11453_CR518","doi-asserted-by":"publisher","first-page":"2939","DOI":"10.4155\/fmc-2019-0130","volume":"11","author":"K Yang","year":"2019","unstructured":"Yang K, Jiang K, Xu Z, Song Y, Wang J (2019) Targeting sphingosine kinase 1 for the treatment of pulmonary arterial hypertension. Future Med Chem 11(22):2939\u20132953. https:\/\/doi.org\/10.4155\/fmc-2019-0130","journal-title":"Future Med Chem"},{"issue":"15","key":"11453_CR519","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.016586","volume":"9","author":"L Meng","year":"2020","unstructured":"Meng L, Teng X, Liu Y, Yang C, Wang S, Yuan W, Meng J, Chi H, Duan L, Liu X (2020) Vital roles of Gremlin-1 in pulmonary arterial hypertension induced by systemic-to-pulmonary shunts. J Am Heart Assoc 9(15):e016586. https:\/\/doi.org\/10.1161\/JAHA.120.016586","journal-title":"J Am Heart Assoc"},{"issue":"2","key":"11453_CR520","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1038\/jhh.2014.59","volume":"29","author":"Q Gu","year":"2015","unstructured":"Gu Q, Yazdanpanah M, van Hoek M, Hofman A, Gao X, de Rooij FW, Sijbrands EJ (2015) Common variants in PCSK1 influence blood pressure and body mass index. J Hum Hypertens 29(2):82\u201386. https:\/\/doi.org\/10.1038\/jhh.2014.59","journal-title":"J Hum Hypertens"},{"issue":"7","key":"11453_CR521","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2020.03.176","volume":"8","author":"F He","year":"2020","unstructured":"He F, Sun B, Li L, Liu M, Lin W, Liu L, Sun Y, Luo Y, Wu L, Lu L et al (2020) TRIB3 rs6037475 is a potential biomarker for predicting felodipine drug response in Chinese patients with hypertension. Ann Transl Med 8(7):437. https:\/\/doi.org\/10.21037\/atm.2020.03.176","journal-title":"Ann Transl Med"},{"issue":"4","key":"11453_CR522","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1177\/1753944715585512","volume":"9","author":"R Satou","year":"2015","unstructured":"Satou R, Shao W, Navar LG (2015) Role of stimulated intrarenal angiotensinogen in hypertension. Ther Adv Cardiovasc Dis 9(4):181\u2013190. https:\/\/doi.org\/10.1177\/1753944715585512","journal-title":"Ther Adv Cardiovasc Dis"},{"issue":"1","key":"11453_CR523","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-023-02385-7","volume":"24","author":"L Su","year":"2023","unstructured":"Su L, Li X, Mao X, Xu T, Zhang Y, Li S, Zhu X, Wang L, Yao D, Wang J et al (2023) Circ-Ntrk2 acts as a miR-296-5p sponge to activate the TGF-\u03b21\/p38 MAPK pathway and promote pulmonary hypertension and vascular remodelling. Respir Res 24(1):78. https:\/\/doi.org\/10.1186\/s12931-023-02385-7","journal-title":"Respir Res"},{"issue":"1","key":"11453_CR524","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1165\/rcmb.2009-0144OC","volume":"43","author":"TA White","year":"2010","unstructured":"White TA, Witt TA, Pan S, Mueske CS, Kleppe LS, Holroyd EW, Champion HC, Simari RD (2010) Tissue factor pathway inhibitor overexpression inhibits hypoxia-induced pulmonary hypertension. Am J Respir Cell Mol Biol 43(1):35\u201345. https:\/\/doi.org\/10.1165\/rcmb.2009-0144OC","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"1","key":"11453_CR525","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-022-08356-4","volume":"23","author":"KY He","year":"2022","unstructured":"He KY, Kelly TN, Wang H, Liang J, Zhu L, Cade BE, Assimes TL, Becker LC, Beitelshees AL, Bielak LF et al (2022) Rare coding variants in RCN3 are associated with blood pressure. BMC Genomics 23(1):148. https:\/\/doi.org\/10.1186\/s12864-022-08356-4","journal-title":"BMC Genomics"},{"issue":"1","key":"11453_CR526","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1053\/j.gastro.2019.03.013","volume":"157","author":"MB Hilscher","year":"2019","unstructured":"Hilscher MB, Sehrawat T, Arab JP, Zeng Z, Gao J, Liu M, Kostallari E, Gao Y, Simonetto DA, Yaqoob U et al (2019) Mechanical stretch increases expression of CXCL1 in liver sinusoidal endothelial cells to recruit neutrophils, generate sinusoidal microthombi, and promote portal hypertension. Gastroenterology 157(1):193-209.e9. https:\/\/doi.org\/10.1053\/j.gastro.2019.03.013","journal-title":"Gastroenterology"},{"issue":"1","key":"11453_CR527","doi-asserted-by":"publisher","first-page":"109","DOI":"10.14715\/cmb\/2022.68.1.14","volume":"68","author":"AA Khaleel","year":"2022","unstructured":"Khaleel AA, Al-Barzinji RMGT (2022) Soluble CD36 concentration in diabetic hypertensive patients with coronary atherosclerosis. Cell Mol Biol (Noisy-le-grand) 68(1):109\u2013116. https:\/\/doi.org\/10.14715\/cmb\/2022.68.1.14","journal-title":"Cell Mol Biol (Noisy-le-grand)"},{"issue":"7","key":"11453_CR528","doi-asserted-by":"publisher","DOI":"10.31083\/j.fbl2807146","volume":"28","author":"Y Zeng","year":"2023","unstructured":"Zeng Y, Jiang Y, Huang Z, Li K, Zhou Y (2023) Association between AGTR1 (c.1166 A>C) polymorphisms and kidney injury in hypertension. Front Biosci (Landmark Ed) 28(7):146. https:\/\/doi.org\/10.31083\/j.fbl2807146","journal-title":"Front Biosci (Landmark Ed)"},{"key":"11453_CR529","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2025.151435","volume":"751","author":"DE Roh","year":"2025","unstructured":"Roh DE, Park NR, Choi BG, Kang Y, Kim JE, Kim YH (2025) TGFBI regulates pulmonary vascular remodeling through endothelial-to-mesenchymal transition in pulmonary arterial hypertension. Biochem Biophys Res Commun 751:151435. https:\/\/doi.org\/10.1016\/j.bbrc.2025.151435","journal-title":"Biochem Biophys Res Commun"},{"issue":"9","key":"11453_CR530","doi-asserted-by":"publisher","DOI":"10.1177\/0300060520935309","volume":"48","author":"F Zhang","year":"2020","unstructured":"Zhang F, Yang M, Xiao T, Hua Y, Chen Y, Xu S, Ni C (2020) SLC6A4 gene L\/S polymorphism and susceptibility to pulmonary arterial hypertension: a meta-analysis. J Int Med Res 48(9):300060520935309. https:\/\/doi.org\/10.1177\/0300060520935309","journal-title":"J Int Med Res"},{"issue":"3","key":"11453_CR531","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1016\/j.gendis.2020.08.008","volume":"9","author":"R Wang","year":"2020","unstructured":"Wang R, Guo Y, Li L, Luo M, Peng L, Lv D, Cheng Z, Xue Q, Wang L, Huang J (2020) Role of thioredoxin-interacting protein in mediating endothelial dysfunction in hypertension. Genes Dis 9(3):753\u2013765. https:\/\/doi.org\/10.1016\/j.gendis.2020.08.008","journal-title":"Genes Dis"},{"key":"11453_CR532","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2022.111780","volume":"559","author":"B Xie","year":"2023","unstructured":"Xie B, Xiong W, Zhang F, Wang N, Luo Y, Chen Y, Cao J, Chen Z, Ma C, Chen H (2023) The miR-103a-3p\/TGFBR3 axis regulates TGF-\u03b2-induced orbital fibroblast activation and fibrosis in thyroid-eye disease. Mol Cell Endocrinol 559:111780. https:\/\/doi.org\/10.1016\/j.mce.2022.111780","journal-title":"Mol Cell Endocrinol"},{"key":"11453_CR533","first-page":"1309","volume":"14","author":"T Li","year":"2008","unstructured":"Li T, Xiao X, Li S, Xing Y, Guo X, Zhang Q (2008) Evaluation of EGR1 as a candidate gene for high myopia. Mol Vis 14:1309\u20131312","journal-title":"Mol Vis"},{"key":"11453_CR534","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2024.110212","volume":"251","author":"Y Yu","year":"2025","unstructured":"Yu Y, Zhang M, Zhou W, Yu Y, Jian L, Zou Y, Pang L, Zou X (2025) miR-151a-5p predicts severity of diabetic retinopathy and protects from retinal cell injury by inactivating MAPK signaling via DKK3. Exp Eye Res 251:110212. https:\/\/doi.org\/10.1016\/j.exer.2024.110212","journal-title":"Exp Eye Res"},{"issue":"12","key":"11453_CR535","doi-asserted-by":"publisher","first-page":"7492","DOI":"10.1167\/iovs.13-12825","volume":"54","author":"M Oishi","year":"2013","unstructured":"Oishi M, Yamashiro K, Miyake M, Akagi-Kurashige Y, Kumagai K, Nakata I, Nakanishi H, Yoshikawa M, Oishi A, Gotoh N et al (2013) Association between ZIC2, RASGRF1, and SHISA6 genes and high myopia in Japanese subjects. Invest Ophthalmol Vis Sci 54(12):7492\u20137497. https:\/\/doi.org\/10.1167\/iovs.13-12825","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"9","key":"11453_CR536","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25094716","volume":"25","author":"TT Ung","year":"2024","unstructured":"Ung TT, Starr CR, Zhylkibayev A, Saltykova I, Gorbatyuk M (2024) Development of TRIB3-based therapy as a gene-independent approach to treat retinal degenerative disorders. Int J Mol Sci 25(9):4716. https:\/\/doi.org\/10.3390\/ijms25094716","journal-title":"Int J Mol Sci"},{"issue":"4","key":"11453_CR537","doi-asserted-by":"publisher","first-page":"3545","DOI":"10.4238\/2011.December.5.4","volume":"10","author":"CH Hsieh","year":"2011","unstructured":"Hsieh CH, Pei D, Hung YJ, Hsiao FC (2011) Association between retinoid-X receptor-gamma genetic polymorphisms and diabetic retinopathy. Genet Mol Res 10(4):3545\u20133551. https:\/\/doi.org\/10.4238\/2011.December.5.4","journal-title":"Genet Mol Res"},{"issue":"1","key":"11453_CR538","doi-asserted-by":"publisher","DOI":"10.1186\/s13148-023-01619-1","volume":"16","author":"C Cai","year":"2024","unstructured":"Cai C, Gu C, He S, Meng C, Lai D, Zhang J, Qiu Q (2024) TET2-mediated ECM1 hypomethylation promotes the neovascularization in active proliferative diabetic retinopathy. Clin Epigenetics 16(1):6. https:\/\/doi.org\/10.1186\/s13148-023-01619-1","journal-title":"Clin Epigenetics"},{"issue":"1","key":"11453_CR539","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-95055-1","volume":"15","author":"A Chmielarz-Czarnoci\u0144ska","year":"2025","unstructured":"Chmielarz-Czarnoci\u0144ska A, Durska A, Skulimowski B, Sobaniec A, Gotz-Wi\u0119ckowska A, Strauss E (2025) Association of the ADRB2 rs1042714 variant with retinopathy of prematurity highlights the importance of the renin-angiotensin-aldosterone system. Sci Rep 15(1):11232. https:\/\/doi.org\/10.1038\/s41598-025-95055-1","journal-title":"Sci Rep"},{"issue":"1","key":"11453_CR540","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3980\/j.issn.2222-3959.2015.01.01","volume":"8","author":"J Tanaka","year":"2015","unstructured":"Tanaka J, Tanaka H, Mizuki N, Nomura E, Ito N, Nomura N, Yamane M, Hida T, Goshima Y, Hatano H et al (2015) Semaphorin 3A controls allergic and inflammatory responses in experimental allergic conjunctivitis. Int J Ophthalmol 8(1):1\u201310. https:\/\/doi.org\/10.3980\/j.issn.2222-3959.2015.01.01","journal-title":"Int J Ophthalmol"},{"key":"11453_CR541","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2022.102438","volume":"56","author":"S Wang","year":"2022","unstructured":"Wang S, Bai J, Zhang YL, Lin QY, Han X, Qu WK, Zhang PF, Ge YS, Zhao Q, Li HH (2022) CXCL1-CXCR2 signalling mediates hypertensive retinopathy by inducing macrophage infiltration. Redox Biol 56:102438. https:\/\/doi.org\/10.1016\/j.redox.2022.102438","journal-title":"Redox Biol"},{"issue":"2","key":"11453_CR542","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.oret.2023.08.022","volume":"8","author":"AA Alshamrani","year":"2024","unstructured":"Alshamrani AA, Magliyah M, Alkuraya FS, Alabdi L, Alfaadhel TA, Alsulaiman SM (2024) Early-onset myopia and retinal detachment without typical microcoria or severe proteinuria due to a novel LAMB2 variant. Ophthalmol Retina 8(2):155\u2013162. https:\/\/doi.org\/10.1016\/j.oret.2023.08.022","journal-title":"Ophthalmol Retina"},{"key":"11453_CR543","doi-asserted-by":"publisher","first-page":"3032","DOI":"10.3389\/fimmu.2019.03032","volume":"10","author":"S Lavalette","year":"2020","unstructured":"Lavalette S, Conart JB, Touhami S, Roubeix C, Houssier M, Augustin S, Raoul W, Combadi\u00e8re C, Febbraio M, Ong H et al (2020) CD36 deficiency inhibits retinal inflammation and retinal degeneration in Cx3cr1 knockout mice. Front Immunol 10:3032. https:\/\/doi.org\/10.3389\/fimmu.2019.03032","journal-title":"Front Immunol"},{"key":"11453_CR544","doi-asserted-by":"publisher","DOI":"10.1007\/s13353-024-00900-0","author":"A Durska","year":"2024","unstructured":"Durska A, Szpecht D, Gotz-Wi\u0119ckowska A, Strauss E (2024) Association of ACE and AGTR1 variants with retinopathy of prematurity: a case-control study and meta-analysis. J Appl Genet. https:\/\/doi.org\/10.1007\/s13353-024-00900-0","journal-title":"J Appl Genet"},{"issue":"6","key":"11453_CR545","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1002\/humu.23737","volume":"40","author":"V Kheir","year":"2019","unstructured":"Kheir V, Cort\u00e9s-Gonz\u00e1lez V, Zenteno JC, Schorderet DF (2019) Mutation update: TGFBI pathogenic and likely pathogenic variants in corneal dystrophies. Hum Mutat 40(6):675\u2013693. https:\/\/doi.org\/10.1002\/humu.23737","journal-title":"Hum Mutat"},{"key":"11453_CR546","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1416181","volume":"15","author":"CM Ahmed","year":"2024","unstructured":"Ahmed CM, Johnson HM, Lewin AS (2024) Corneal application of SOCS1\/3 peptides for the treatment of eye diseases mediated by inflammation and oxidative stress. Front Immunol 15:1416181. https:\/\/doi.org\/10.3389\/fimmu.2024.1416181","journal-title":"Front Immunol"},{"issue":"9","key":"11453_CR547","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1101\/gr.074302.107","volume":"18","author":"AC Wiik","year":"2008","unstructured":"Wiik AC, Wade C, Biagi T, Ropstad EO, Bjerk\u00e5s E, Lindblad-Toh K, Lingaas F (2008) Deletion in nephronophthisis 4 (NPHP4) is associated with recessive cone-rod dystrophy in standard wire-haired dachshund. Genome Res 18(9):1415\u20131421. https:\/\/doi.org\/10.1101\/gr.074302.107","journal-title":"Genome Res"},{"key":"11453_CR548","doi-asserted-by":"publisher","DOI":"10.4172\/2155-9570.1000287","volume":"4","author":"LP Singh","year":"2013","unstructured":"Singh LP (2013) Thioredoxin interacting protein (TXNIP) and pathogenesis of diabetic retinopathy. J Clin Exp Ophthalmol 4:10.4172\/2155-9570.1000287. https:\/\/doi.org\/10.4172\/2155-9570.1000287","journal-title":"J Clin Exp Ophthalmol"},{"issue":"6","key":"11453_CR549","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1002\/ana.25356","volume":"84","author":"SS Karuppagounder","year":"2018","unstructured":"Karuppagounder SS, Alin L, Chen Y, Brand D, Bourassa MW, Dietrich K, Wilkinson CM, Nadeau CA, Kumar A, Perry S et al (2018) N-acetylcysteine targets 5 lipoxygenase-derived, toxic lipids and can synergize with prostaglandin E2 to inhibit ferroptosis and improve outcomes following hemorrhagic stroke in mice. Ann Neurol 84(6):854\u2013872. https:\/\/doi.org\/10.1002\/ana.25356","journal-title":"Ann Neurol"},{"key":"11453_CR550","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.neuroscience.2016.05.013","volume":"330","author":"D Michalski","year":"2016","unstructured":"Michalski D, Prei\u00dfler H, Hofmann S, Kacza J, H\u00e4rtig W (2016) Decline of microtubule-associated protein tau after experimental stroke in differently aged wild-type and 3xTg mice with Alzheimer-like alterations. Neuroscience 330:1\u201311. https:\/\/doi.org\/10.1016\/j.neuroscience.2016.05.013","journal-title":"Neuroscience"},{"key":"11453_CR551","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2025.05.020","author":"T Wang","year":"2025","unstructured":"Wang T, Wang R, Zeng J, Zhao W, Liu Y, Xiao H (2025) A novel predictive model constructed based on the combination of SIX3OS1, miR-511-3p and RBP4 for stroke-prost cognitive impairment. Neuroscience. https:\/\/doi.org\/10.1016\/j.neuroscience.2025.05.020","journal-title":"Neuroscience"},{"issue":"12","key":"11453_CR552","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2020.105255","volume":"29","author":"YY Li","year":"2020","unstructured":"Li YY, Guo JH, Liu YQ, Dong JH, Zhu CH (2020) PPAR\u03b3 activation-mediated Egr-1 inhibition benefits against brain injury in an experimental ischaemic stroke model. J Stroke Cerebrovasc Dis 29(12):105255. https:\/\/doi.org\/10.1016\/j.jstrokecerebrovasdis.2020.105255","journal-title":"J Stroke Cerebrovasc Dis"},{"issue":"3","key":"11453_CR553","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1172\/JCI4953","volume":"103","author":"M Endres","year":"1999","unstructured":"Endres M, Fink K, Zhu J, Stagliano NE, Bondada V, Geddes JW, Azuma T, Mattson MP, Kwiatkowski DJ, Moskowitz MA (1999) Neuroprotective effects of gelsolin during murine stroke. J Clin Invest 103(3):347\u2013354. https:\/\/doi.org\/10.1172\/JCI4953","journal-title":"J Clin Invest"},{"issue":"1","key":"11453_CR554","doi-asserted-by":"publisher","DOI":"10.1111\/ene.16548","volume":"32","author":"W Dong","year":"2025","unstructured":"Dong W, Lu Y, Long J, Peng Y, Ju Z, Xu T, Zhang Y, Zhai G, Zhong C (2025) Plasma neuropeptide Y levels and adverse clinical outcomes after acute ischaemic stroke. Eur J Neurol 32(1):e16548. https:\/\/doi.org\/10.1111\/ene.16548","journal-title":"Eur J Neurol"},{"key":"11453_CR555","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinsp.2024.100360","volume":"79","author":"D Zhou","year":"2024","unstructured":"Zhou D, Qin H, Miao L, Xu Y, Yu L, Wang J (2024) Predictive value of glycoprotein DKK3 for early neurological deterioration after ischemic stroke. Clinics (Sao Paulo) 79:100360. https:\/\/doi.org\/10.1016\/j.clinsp.2024.100360","journal-title":"Clinics (Sao Paulo)"},{"issue":"3","key":"11453_CR556","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1055\/s-0040-1717116","volume":"121","author":"HY Chiou","year":"2021","unstructured":"Chiou HY, Bai CH, Lien LM, Hu CJ, Jeng JS, Tang SC, Lin HJ, Hsieh YC (2021) Interactive effects of a combination of the HDAC3 and HDAC9 genes with diabetes mellitus on the risk of ischemic stroke. Thromb Haemost 121(3):396\u2013404. https:\/\/doi.org\/10.1055\/s-0040-1717116","journal-title":"Thromb Haemost"},{"issue":"12","key":"11453_CR557","doi-asserted-by":"publisher","first-page":"3182","DOI":"10.1161\/STROKEAHA.123.044862","volume":"54","author":"HS Markus","year":"2023","unstructured":"Markus HS (2023) HDAC9 inhibition as a novel treatment for stroke. Stroke 54(12):3182\u20133189. https:\/\/doi.org\/10.1161\/STROKEAHA.123.044862","journal-title":"Stroke"},{"issue":"4","key":"11453_CR558","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.5114\/aoms\/176740","volume":"20","author":"Y Li","year":"2024","unstructured":"Li Y, Li N, Xi L, Li L (2024) Predictive value of the BDH2-MN2 nomogram model for prognosis at 3 months after receiving intravenous thrombolysis in patients with acute ischemic stroke. Arch Med Sci 20(4):1143\u20131152. https:\/\/doi.org\/10.5114\/aoms\/176740","journal-title":"Arch Med Sci"},{"issue":"2","key":"11453_CR559","doi-asserted-by":"publisher","first-page":"189","DOI":"10.14715\/cmb\/2024.70.2.27","volume":"70","author":"T Hu","year":"2024","unstructured":"Hu T, Lin Y (2024) miR-127-5p regulates FAIM2-mediated cell apoptosis and participates in cerebral ischemia-reperfusion injury. Cell Mol Biol (Noisy-le-grand) 70(2):189\u2013196. https:\/\/doi.org\/10.14715\/cmb\/2024.70.2.27","journal-title":"Cell Mol Biol (Noisy-le-grand)"},{"key":"11453_CR560","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.gene.2018.11.080","volume":"688","author":"I Isordia-Salas","year":"2019","unstructured":"Isordia-Salas I, Santiago-Germ\u00e1n D, Cerda-Mancillas MC, Hern\u00e1ndez-Ju\u00e1rez J, Bernabe-Garc\u00eda M, Lea\u00f1os-Miranda A, Alvarado-Moreno JA, Majluf-Cruz A (2019) Gene polymorphisms of angiotensin-converting enzyme and angiotensinogen and risk of idiopathic ischemic stroke. Gene 688:163\u2013170. https:\/\/doi.org\/10.1016\/j.gene.2018.11.080","journal-title":"Gene"},{"key":"11453_CR561","doi-asserted-by":"publisher","first-page":"577","DOI":"10.2147\/PGPM.S270319","volume":"13","author":"J Shi","year":"2020","unstructured":"Shi J, Sun Y, Hua J (2020) Functional genetic variation in the 3\u2019-UTRNTRK2 is associated with risk of ischemic stroke. Pharmgenomics Pers Med 13:577\u2013584. https:\/\/doi.org\/10.2147\/PGPM.S270319","journal-title":"Pharmgenomics Pers Med"},{"issue":"4","key":"11453_CR562","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1161\/STROKEAHA.111.643072","volume":"43","author":"JE Rossouw","year":"2012","unstructured":"Rossouw JE, Johnson KC, Pettinger M, Cushman M, Sandset PM, Kuller L, Rosendaal F, Rosing J, Wasserthal-Smoller S, Martin LW et al (2012) Tissue factor pathway inhibitor, activated protein C resistance, and risk of ischemic stroke due to postmenopausal hormone therapy. Stroke 43(4):952\u2013957. https:\/\/doi.org\/10.1161\/STROKEAHA.111.643072","journal-title":"Stroke"},{"key":"11453_CR563","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2023.1169617","volume":"10","author":"RM Barber","year":"2023","unstructured":"Barber RM, Platt SR, De Risio L, Barber J, Robinson KR (2023) Multiplex analysis of cytokines in the cerebrospinal fluid of dogs after ischemic stroke reveals elevations in chemokines CXCL1 and MCP-1. Front Vet Sci 10:1169617. https:\/\/doi.org\/10.3389\/fvets.2023.1169617","journal-title":"Front Vet Sci"},{"issue":"7","key":"11453_CR564","doi-asserted-by":"publisher","first-page":"595","DOI":"10.3109\/1354750X.2013.836244","volume":"18","author":"G Altarescu","year":"2013","unstructured":"Altarescu G, Haim S, Elstein D (2013) Angiotensinogen promoter and angiotensinogen II receptor type 1 gene polymorphisms and incidence of ischemic stroke and neurologic phenotype in Fabry disease. Biomarkers 18(7):595\u2013600. https:\/\/doi.org\/10.3109\/1354750X.2013.836244","journal-title":"Biomarkers"},{"key":"11453_CR565","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/j.neuint.2016.11.007","volume":"107","author":"L Yang","year":"2017","unstructured":"Yang L, Kong Y, Ren H, Li M, Wei CJ, Shi E, Jin WN, Hao J, Vandenbark AA, Offner H (2017) Upregulation of CD74 and its potential association with disease severity in subjects with ischemic stroke. Neurochem Int 107:148\u2013155. https:\/\/doi.org\/10.1016\/j.neuint.2016.11.007","journal-title":"Neurochem Int"},{"issue":"4","key":"11453_CR566","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1007\/s12017-016-8406-x","volume":"18","author":"Q Ma","year":"2016","unstructured":"Ma Q, Liu N, Zhang R, Li X, Zhang H, Li Z, Zhang S, Hou W, Zhu Q, Zheng H et al (2016) A novel association of the suppressor of cytokine signaling 1 (SOCS1) gene polymorphisms in ischemic stroke patients. Neuromol Med 18(4):573\u2013580. https:\/\/doi.org\/10.1007\/s12017-016-8406-x","journal-title":"Neuromol Med"},{"issue":"1","key":"11453_CR567","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-81854-9","volume":"11","author":"HJ Kang","year":"2021","unstructured":"Kang HJ, Lee EH, Kim JW, Kim SW, Shin IS, Kim JT, Park MS, Cho KH, Han JS, Lyoo IK et al (2021) Association of SLC6A4 methylation with long-term outcomes after stroke: focus on the interaction with suicidal ideation. Sci Rep 11(1):2710. https:\/\/doi.org\/10.1038\/s41598-021-81854-9","journal-title":"Sci Rep"},{"issue":"9","key":"11453_CR568","doi-asserted-by":"publisher","first-page":"2020","DOI":"10.2337\/db21-0958","volume":"71","author":"M Chen","year":"2022","unstructured":"Chen M, Hu R, Cavinato C, Zhuang ZW, Zhang J, Yun S, Fernandez Tussy P, Singh A, Murtada SI et al (2022) Fibronectin-integrin \u03b15 signaling in vascular complications of type 1 diabetes. Diabetes 71(9):2020\u20132033. https:\/\/doi.org\/10.2337\/db21-0958","journal-title":"Diabetes"},{"issue":"6","key":"11453_CR569","doi-asserted-by":"publisher","first-page":"728","DOI":"10.2337\/db22-0718","volume":"72","author":"KZ Rokamp","year":"2023","unstructured":"Rokamp KZ, Dela F, Secher NH, Gr\u00f8nlykke L, Thorsteinsson B, Pedersen-Bjergaard U (2023) Impact of polymorphism in the \u03b22-receptor gene on the metabolic response to epinephrine after repeated hypoglycemia. Diabetes 72(6):728\u2013734. https:\/\/doi.org\/10.2337\/db22-0718","journal-title":"Diabetes"},{"key":"11453_CR570","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2023.104625","volume":"92","author":"T Suomi","year":"2023","unstructured":"Suomi T, Starskaia I, Kalim UU, Rasool O, Jaakkola MK, Gr\u00f6nroos T, V\u00e4likangas T, Brorsson C, Mazzoni G, Bruggraber S et al (2023) Gene expression signature predicts rate of type 1 diabetes progression. EBioMedicine 92:104625. https:\/\/doi.org\/10.1016\/j.ebiom.2023.104625","journal-title":"EBioMedicine"},{"key":"11453_CR571","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2018.00105","volume":"9","author":"D Aizen","year":"2018","unstructured":"Aizen D, Pasmanik-Chor M, Sarfstein R, Laron Z, Bruchim I, Werner H (2018) Genome-wide analyses identify Filamin-A as a novel downstream target for insulin and IGF1 action. Front Endocrinol (Lausanne) 9:105. https:\/\/doi.org\/10.3389\/fendo.2018.00105","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"4","key":"11453_CR572","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.18127","volume":"28","author":"S Song","year":"2024","unstructured":"Song S, Yu J (2024) Identification of the shared genes in type 2 diabetes mellitus and osteoarthritis and the role of quercetin. J Cell Mol Med 28(4):e18127. https:\/\/doi.org\/10.1111\/jcmm.18127","journal-title":"J Cell Mol Med"},{"key":"11453_CR573","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1203542","volume":"14","author":"HJ Cho","year":"2023","unstructured":"Cho HJ, Gurbuz F, Stamou M, Kotan LD, Farmer SM, Can S, Tompkins MF, Mammadova J, Altincik SA, Gokce C et al (2023) POU6F2 mutation in humans with pubertal failure alters GnRH transcript expression. Front Endocrinol (Lausanne) 14:1203542. https:\/\/doi.org\/10.3389\/fendo.2023.1203542","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"12","key":"11453_CR574","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0294661","volume":"18","author":"YH Ling","year":"2023","unstructured":"Ling YH, Chen Y, Leung KN, Chan KM, Liu WK (2023) Cell cycle regulation of the psoriasis associated gene CCHCR1 by transcription factor E2F1. PLoS ONE 18(12):e0294661. https:\/\/doi.org\/10.1371\/journal.pone.0294661","journal-title":"PLoS ONE"},{"issue":"6","key":"11453_CR575","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1530\/EJE-12-0579","volume":"167","author":"EH Gan","year":"2012","unstructured":"Gan EH, MacArthur K, Mitchell AL, Pearce SH (2012) The role of functionally defective rare germline variants of sialic acid acetylesterase in autoimmune Addison\u2019s disease. Eur J Endocrinol 167(6):825\u2013828. https:\/\/doi.org\/10.1530\/EJE-12-0579","journal-title":"Eur J Endocrinol"},{"issue":"4","key":"11453_CR576","doi-asserted-by":"publisher","first-page":"687","DOI":"10.3892\/mmr.2011.480","volume":"4","author":"L Yu","year":"2011","unstructured":"Yu L, Nian Z, Sang J (2011) Osteosarcoma amplified 9 is highly expressed in mouse adipocytes and controls lipid storage. Mol Med Rep 4(4):687\u2013692. https:\/\/doi.org\/10.3892\/mmr.2011.480","journal-title":"Mol Med Rep"},{"issue":"14","key":"11453_CR577","doi-asserted-by":"publisher","first-page":"7475","DOI":"10.1021\/acs.jmedchem.0c00191","volume":"63","author":"D Piomelli","year":"2020","unstructured":"Piomelli D, Scalvini L, Fotio Y, Lodola A, Spadoni G, Tarzia G, Mor M (2020) N-acylethanolamine acid amidase (NAAA): structure, function, and inhibition. J Med Chem 63(14):7475\u20137490. https:\/\/doi.org\/10.1021\/acs.jmedchem.0c00191","journal-title":"J Med Chem"},{"issue":"2","key":"11453_CR578","doi-asserted-by":"publisher","first-page":"1708","DOI":"10.3892\/ol.2018.8794","volume":"16","author":"W Liu","year":"2018","unstructured":"Liu W, Wan X, Mu Z, Li F, Wang L, Zhao J, Huang X (2018) MiR-1256 suppresses proliferation and migration of non-small cell lung cancer via regulating TCTN1. Oncol Lett 16(2):1708\u20131714. https:\/\/doi.org\/10.3892\/ol.2018.8794","journal-title":"Oncol Lett"},{"key":"11453_CR579","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1186\/1756-0500-6-491","volume":"6","author":"CV Collares","year":"2013","unstructured":"Collares CV, Evangelista AF, Xavier DJ, Rassi DM, Arns T, Foss-Freitas MC, Foss MC, Puthier D, Sakamoto-Hojo ET, Passos GA et al (2013) Identifying common and specific microRNAs expressed in peripheral blood mononuclear cell of type 1, type 2, and gestational diabetes mellitus patients. BMC Res Notes 6:491. https:\/\/doi.org\/10.1186\/1756-0500-6-491","journal-title":"BMC Res Notes"},{"issue":"11","key":"11453_CR580","doi-asserted-by":"publisher","first-page":"5663","DOI":"10.3390\/ijms25115663","volume":"25","author":"AHG Pinheiro","year":"2024","unstructured":"Pinheiro AHG, Pereira BO, Silva LSD, Melo FTC, Souza ACCB, Leal VSG, Figueiredo PBB, Neto JFA, Santos MCD, Queiroz NNM et al (2024) Downregulation of hsa-miR-100-5p May Be a Protective Factor in the Early Stages of Nephropathy in Type 1 Diabetes Mellitus. Int J Mol Sci 25(11):5663. https:\/\/doi.org\/10.3390\/ijms25115663","journal-title":"Int J Mol Sci"},{"key":"11453_CR581","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.01637","volume":"10","author":"AS Santos","year":"2019","unstructured":"Santos AS, Cunha Neto E, Fukui RT, Ferreira LRP, Silva MER (2019) Increased expression of circulating microRNA 101-3p in type 1 diabetes patients: new insights into miRNA-regulated pathophysiological pathways for type 1 diabetes. Front Immunol 10:1637. https:\/\/doi.org\/10.3389\/fimmu.2019.01637","journal-title":"Front Immunol"},{"key":"11453_CR582","doi-asserted-by":"publisher","first-page":"105156","DOI":"10.1016\/j.neuint.2021.105156","volume":"150","author":"Y Wang","year":"2022","unstructured":"Wang Y, Wang S, Zhang W, Liu J, Yang Z, Liu C (2022) Notch1 participates in the activation of autophagy in the hippocampus of type I diabetic mice. Neurochem Int 150:105156","journal-title":"Neurochem Int"},{"key":"11453_CR583","doi-asserted-by":"publisher","first-page":"955","DOI":"10.2147\/IJGM.S350732","volume":"15","author":"Y Zhong","year":"2022","unstructured":"Zhong Y, Du G, Liu J, Li S, Lin J, Deng G, Wei J, Huang J (2022) RUNX1 and CCL3 in diabetes mellitus-related coronary artery disease: a bioinformatics analysis. Int J Gen Med 15:955\u2013963. https:\/\/doi.org\/10.2147\/IJGM.S350732","journal-title":"Int J Gen Med"},{"issue":"10","key":"11453_CR584","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1007\/s00592-023-02128-6","volume":"60","author":"C Zusi","year":"2023","unstructured":"Zusi C, Rioda M, Maguolo A, Emiliani F, Unali I, Costantini S, Corradi M, Contreas G, Morandi A, Maffeis C (2023) IGF1 and PPARG polymorphisms are associated with reduced estimated glomerular filtration rate in a cohort of children and adolescents with type 1 diabetes. Acta Diabetol 60(10):1351\u20131358. https:\/\/doi.org\/10.1007\/s00592-023-02128-6","journal-title":"Acta Diabetol"}],"container-title":["Molecular Diversity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11030-025-11453-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11030-025-11453-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11030-025-11453-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T23:04:59Z","timestamp":1783206299000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11030-025-11453-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,14]]},"references-count":584,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,8]]}},"alternative-id":["11453"],"URL":"https:\/\/doi.org\/10.1007\/s11030-025-11453-7","relation":{},"ISSN":["1573-501X"],"issn-type":[{"value":"1573-501X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,14]]},"assertion":[{"value":"2 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Preprint source"}}]}}