{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T12:00:44Z","timestamp":1774785644881,"version":"3.50.1"},"reference-count":66,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2007,12,13]],"date-time":"2007-12-13T00:00:00Z","timestamp":1197504000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2009,3]]},"DOI":"10.1007\/s11033-007-9197-9","type":"journal-article","created":{"date-parts":[[2007,12,12]],"date-time":"2007-12-12T11:48:25Z","timestamp":1197460105000},"page":"431-436","source":"Crossref","is-referenced-by-count":34,"title":["Pigmentation in Black-boned sheep (Ovis aries): association with polymorphism of the MC1R gene"],"prefix":"10.1007","volume":"36","author":[{"given":"W. D.","family":"Deng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Shu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. L.","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X. W.","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. M.","family":"Mao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2007,12,13]]},"reference":[{"key":"9197_CR1","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1038\/nature05098","volume":"443","author":"JA D\u2019Orazio","year":"2006","unstructured":"D\u2019Orazio JA, Nobuhisa T, Cui R, Arya M, Spry M, Wakamatsu K, Igras V, Kunisada T, Granter SR, Nishimura EK, Ito S, Fisher DE (2006) Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning. Nature 443:340\u2013344","journal-title":"Nature"},{"key":"9197_CR2","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1126\/science.315.5816.1214","volume":"315","author":"I Wickelgren","year":"2007","unstructured":"Wickelgren I (2007a) Skin biology. A healthy tan? Science 315:1214\u20131216","journal-title":"Science"},{"key":"9197_CR3","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1126\/science.315.5816.1214","volume":"315","author":"I Wickelgren","year":"2007","unstructured":"Wickelgren I (2007b) Skin biology. Why I have red hair, need to avoid the sun, and shouldn\u2019t commit a crime. Science 315:1215","journal-title":"Science"},{"key":"9197_CR4","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/nature05660","volume":"445","author":"JY Lin","year":"2007","unstructured":"Lin JY, Fisher DE (2007) Melanocyte biology and skin pigmentation. Nature 445:843\u2013850","journal-title":"Nature"},{"key":"9197_CR5","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/0014-5793(92)80820-7","volume":"309","author":"V Chhajlani","year":"1992","unstructured":"Chhajlani V, Wikberg JES (1992) Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA. FEBS Lett 309:417\u2013420","journal-title":"FEBS Lett"},{"key":"9197_CR6","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1126\/science.1325670","volume":"257","author":"KG Mountjoy","year":"1992","unstructured":"Mountjoy KG, Robbins LS, Mortrud MT, Cone RD (1992) The cloning of a family of genes that encode the melanocortin receptors. Science 257:1248\u20131251","journal-title":"Science"},{"key":"9197_CR7","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/0092-8674(93)90572-8","volume":"72","author":"LS Robbins","year":"1993","unstructured":"Robbins LS, Nadeau JH, Johnson KR, Kelly MA, Roselli-Rehfuss L, Baack E, Mountjoy KG, Cone RD (1993) Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function. Cell 72:827\u2013834","journal-title":"Cell"},{"key":"9197_CR8","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1034\/j.1600-0749.2000.130209.x","volume":"13","author":"S Takeuchi","year":"2000","unstructured":"Takeuchi S, Takeuchi T, Yamamoto H (2000) A possible mechanism for feedback regulation of the mouse tyrosinase gene by its 3\u2032 non-coding RNA fragments. Pigment Cell Res 13:109\u2013115","journal-title":"Pigment Cell Res"},{"key":"9197_CR9","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1034\/j.1600-0749.2002.02027.x","volume":"15","author":"R Han","year":"2002","unstructured":"Han R, Baden HP, Brissette JL, Weiner L (2002) Redefining the skin\u2019s pigmentary system with a novel tyrosinase assay. Pigment Cell Res 15:290\u2013297","journal-title":"Pigment Cell Res"},{"key":"9197_CR10","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1152\/physrev.00044.2003","volume":"84","author":"A Slominski","year":"2004","unstructured":"Slominski A, Tobin DJ, Shibahara S, Wortsman J (2004) Melanin pigmentation in mammalian skin and its hormonal regulation. Physiol Rev 84:1155\u20131228","journal-title":"Physiol Rev"},{"key":"9197_CR11","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/j.1600-0749.2005.00213.x","volume":"18","author":"AM Hall","year":"2005","unstructured":"Hall AM, Orlow SJ (2005) Degradation of tyrosinase induced by phenylthiourea occurs following Golgi maturation. Pigment Cell Res 18:122\u2013129","journal-title":"Pigment Cell Res"},{"key":"9197_CR12","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1111\/j.1365-2052.2006.01530.x","volume":"37","author":"WD Deng","year":"2006","unstructured":"Deng WD, Yang SL, Huo YQ, Gou X, Shi XW, Mao HM (2006) Physiological and genetic characteristics of black-boned sheep (Ovis aries). Anim Genet 37:586\u2013588","journal-title":"Anim Genet"},{"key":"9197_CR13","unstructured":"Mao HM, Deng WD, Sun SR, Shu W, Yang SL (2005) Studies on the specific characteristics of Yunnan Black-bone sheep (in Chinese, with English abstract). J Yunnan Agric Univ 20:89\u201393, F1"},{"key":"9197_CR14","volume-title":"Molecular cloning: a laboratory manual","author":"J Sambrook","year":"1989","unstructured":"Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor Laboratory Press, New York, NY","edition":"2"},{"key":"9197_CR15","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1046\/j.1365-2052.2003.00985.x","volume":"34","author":"TG Berryere","year":"2003","unstructured":"Berryere TG, Schmutz SM, Schimpf RJ, Cowan CM, Potter J (2003) TYRP1 is associated with dun coat colour in Dexter cattle or how now brown cow? Anim Genet 34:169\u2013175","journal-title":"Anim Genet"},{"key":"9197_CR16","doi-asserted-by":"crossref","first-page":"4673","DOI":"10.1093\/nar\/22.22.4673","volume":"22","author":"JD Thompson","year":"1994","unstructured":"Thompson JD, Higgins DG, Gibson TJ (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucl Acids Res 22:4673\u20134680","journal-title":"Nucl Acids Res"},{"key":"9197_CR17","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1016\/S0021-9258(19)67976-7","volume":"238","author":"SH Pomerantz","year":"1963","unstructured":"Pomerantz SH (1963) Separation, purification, and properties of two tyrosinases from hamster melanoma. J Biol Chem 238:2351\u20132357","journal-title":"J Biol Chem"},{"key":"9197_CR18","volume-title":"Principles and procedures of statistics: a biometrical approach","author":"RGD Steel","year":"1980","unstructured":"Steel RGD, Torrie JH (1980) Principles and procedures of statistics: a biometrical approach, 2nd edn. McGraw-Hill Book Company, New York","edition":"2"},{"key":"9197_CR19","first-page":"287","volume":"51","author":"RD Cone","year":"1996","unstructured":"Cone RD, Lu D, Koppula S, Vage DI, Klungland H, Boston B, Chen W, Orth DN, Pouton C, Kesterson RA (1996) The melanocortin receptors: agonist, antagonists, and the hormonal control of pigmentation. Recent Prog Horm Res 51:287\u2013318","journal-title":"Recent Prog Horm Res"},{"issue":"Suppl 8","key":"9197_CR20","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1034\/j.1600-0749.13.s8.19.x","volume":"13","author":"S Ito","year":"2000","unstructured":"Ito S, Wakamatsu K, Ozeki H (2000) Chemical analysis of melanins and its application to the study of the regulation of melanogenesis. Pigment Cell Res 13(Suppl 8):103\u2013109","journal-title":"Pigment Cell Res"},{"key":"9197_CR21","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1034\/j.1600-0749.2003.00072.x","volume":"16","author":"S Ito","year":"2003","unstructured":"Ito S, Wakamatsu K (2003) Quantitative analysis of eumelanin and pheomelanin in humans, mice, and other animals: a comparative review. Pigment Cell Res 16:523\u2013531","journal-title":"Pigment Cell Res"},{"key":"9197_CR22","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1600-0749.2005.00288.x","volume":"19","author":"N Wang","year":"2006","unstructured":"Wang N, Hebert DN (2006) Tyrosinase maturation through the mammalian secretary pathway: bringing color to life. Pigment Cell Res 19:3\u201318","journal-title":"Pigment Cell Res"},{"key":"9197_CR23","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1172\/JCI108014","volume":"55","author":"SH Pomerantz","year":"1975","unstructured":"Pomerantz SH, Ances IG (1975) Tyrosinase activity in human skin. Influence of race and age in newborns. J Clin Invest 55:1127\u20131131","journal-title":"J Clin Invest"},{"key":"9197_CR24","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/1523-1747.ep12872677","volume":"95","author":"M Iwata","year":"1990","unstructured":"Iwata M, Corn T, Iwata S, Everett MA, Fuller BB (1990) The relationship between tyrosinase activity and skin color in human foreskins. J Invest Dermatol 95:9\u201315","journal-title":"J Invest Dermatol"},{"key":"9197_CR25","doi-asserted-by":"crossref","first-page":"223","DOI":"10.2174\/1389202003351364","volume":"1","author":"H Klungland","year":"2000","unstructured":"Klungland H, Vage DI (2000) Molecular genetics of pigmentation in domestic animals. Curr Genomics 1:223\u2013242","journal-title":"Curr Genomics"},{"key":"9197_CR26","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s003359900939","volume":"10","author":"DI Vage","year":"1999","unstructured":"Vage DI, Klungland H, Lu D, Cone RD (1999) Molecular and pharmacological characterization of dominant black coat color in sheep. Mamm Genome 10:39\u201343","journal-title":"Mamm Genome"},{"key":"9197_CR27","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1046\/j.1600-0749.2003.00090.x","volume":"16","author":"DI Vage","year":"2003","unstructured":"Vage DI, Fleet MR, Ponz R, Olsen RT, Monteagudo LV, Tejedor MT, Arruga MV, Gagliardi R, Postiglioni A, Nattrass GS, Klungland H (2003) Mapping and characterization of the dominant black colour locus in sheep. Pigment Cell Res 16:693\u2013697","journal-title":"Pigment Cell Res"},{"key":"9197_CR28","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1007\/BF00352371","volume":"6","author":"H Klungland","year":"1995","unstructured":"Klungland H, Vage DI, Gomez-Raya L, Adalsteinsson S, Lien S (1995) The role of melanocyte-stimulating hormone (MSH) receptor in bovine coat color determination. Mamm Genome 6:636\u2013639","journal-title":"Mamm Genome"},{"key":"9197_CR29","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/j.1740-0929.2005.00247.x","volume":"76","author":"S Sasazaki","year":"2005","unstructured":"Sasazaki S, Usui M, Mannen H, Hiura C, Tsuji S (2005) Allele frequencies of the extension locus encoding the melanocortin-1 receptor in Japanese and Korean cattle. Anim Sci J 76:129\u2013132","journal-title":"Anim Sci J"},{"key":"9197_CR30","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0378-1119(01)00694-1","volume":"277","author":"RA Sturm","year":"2001","unstructured":"Sturm RA, Teasdale RD, Box NF (2001) Human pigmentation genes: identification, structure and consequences of polymorphisms variations. Gene 277:49\u201362","journal-title":"Gene"},{"key":"9197_CR31","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1093\/hmg\/ddh043","volume":"13","author":"DL Duffy","year":"2004","unstructured":"Duffy DL, Box NF, Chen W, Palmer JS, Montgomery GW, James MR, Hayward NK, Martin NG, Sturm RA (2004) Interactive effects of MC1R and OCA2 on melanoma risk phenotypes. Hum Mol Genet 13:447\u2013461","journal-title":"Hum Mol Genet"},{"key":"9197_CR32","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1093\/hmg\/ddi219","volume":"14","author":"KA Beaumont","year":"2005","unstructured":"Beaumont KA, Newton RA, Smit DJ, Leonard JH, Stow JL, Sturm RA (2005) Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk. Hum Mol Genet 14:2145\u20132154","journal-title":"Hum Mol Genet"},{"key":"9197_CR33","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1111\/j.1556-4029.2006.00361.x","volume":"52","author":"W Branicki","year":"2007","unstructured":"Branicki W, Brudnik U, Kupiec T, Wolanska-Nowak P, Wojas-Pelc A (2007) Determination of phenotype associated SNPs in the MC1R gene. J Forensic Sci 52:349\u2013354","journal-title":"J Forensic Sci"},{"key":"9197_CR34","doi-asserted-by":"crossref","first-page":"5268","DOI":"10.1073\/pnas.0431157100","volume":"100","author":"MW Nachman","year":"2003","unstructured":"Nachman MW, Hoekstra HE, D\u2019Agostino SL (2003) The genetic basis of adaptive melanism in pocket mice. Proc Natl Acad Sci USA 100:5268\u20135273","journal-title":"Proc Natl Acad Sci USA"},{"issue":"suppl 2","key":"9197_CR35","first-page":"35","volume":"25","author":"M Johansson","year":"1994","unstructured":"Johansson M, Marklund L, Sandberg K, Andersson L, 1994. Cosegregation between the chestnut coat colour in horses and polymorphisms at the melanocyte stimulating hormone (MSH) receptor locus. Anim Genet 25(suppl 2):35","journal-title":"Anim Genet"},{"key":"9197_CR36","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1007\/s003359900264","volume":"7","author":"L Marklund","year":"1996","unstructured":"Marklund L, Johansson Moller M, Sandberg K, Andersson L (1996) A missense mutation in the gene for melanocyte stimulating hormone receptor (MC1R) is associated with the chestnut color in horses. Mamm Genome 7:895\u2013899","journal-title":"Mamm Genome"},{"key":"9197_CR37","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1007\/s003350020017","volume":"12","author":"S Rieder","year":"2001","unstructured":"Rieder S, Taourit S, Mariat D, Langlois B, Guerin G (2001) Mutations in the agouti (ASIP), the extention (MC1R), and the brown (TYRP) loci and their association to coat color phenotypes in horses (Equus caballus). Mamm Genome 12:450\u2013455","journal-title":"Mamm Genome"},{"key":"9197_CR38","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/ng0397-311","volume":"15","author":"DI Vage","year":"1997","unstructured":"Vage DI, Lu D, Klungland H, Lien S, Adalsteinsson S, Cone RD (1997) A non-epistatic interaction of agouti and extension in the fox, Vulpes vulpes. Nat Genet 15:311\u2013315","journal-title":"Nat Genet"},{"key":"9197_CR39","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/S0960-9822(03)00128-3","volume":"13","author":"E Eizirik","year":"2003","unstructured":"Eizirik E, Yuhki N, Johnson WE, Menotti-Raymond M, Hannah SS, O\u2019Brien SJ (2003) Molecular genetics and evolution of melanism in the cat family. Curr Biol 13:448\u2013453","journal-title":"Curr Biol"},{"key":"9197_CR40","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1046\/j.1365-2052.2000.00639.x","volume":"31","author":"RE Everts","year":"2000","unstructured":"Everts RE, Rothuizen J, van Oost BA (2000) Identification of a premature stop codon in the melanocyte-stimulating hormone receptor gene (MC1R) in Labrador and golden retrievers with yellow coat colour. Anim Genet 31:194\u2013199","journal-title":"Anim Genet"},{"key":"9197_CR41","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s003350010005","volume":"11","author":"JM Newton","year":"2000","unstructured":"Newton JM, Wilkie AL, He L, Jordan SA, Metallinos DL, Holmes NG, Jackson IJ, Barsh GS (2000) Melanocortin 1 receptor variation in the domestic dog. Mamm Genome 11:24\u201330","journal-title":"Mamm Genome"},{"key":"9197_CR42","first-page":"75","volume":"94","author":"JA Kerns","year":"2003","unstructured":"Kerns JA, Olivier M, Lust G, Barsh GS (2003) Exclusion of melanocortin-1 receptor (Mc1r) and Agouti as candidates for dominant black in dogs. J Hered 94:75\u201379","journal-title":"J Hered"},{"key":"9197_CR43","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1007\/s00335-004-2377-1","volume":"15","author":"JA Kerns","year":"2004","unstructured":"Kerns JA, Newton J, Berryere TG, Rubin EM, Cheng JF, Schmutz SM, Barsh GS (2004) Characterization of the dog Agouti gene and a non agouti mutation in German Shepherd Dogs. Mamm Genome 15:798\u2013808","journal-title":"Mamm Genome"},{"key":"9197_CR44","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1093\/jhered\/esg014","volume":"94","author":"SM Schmutz","year":"2003","unstructured":"Schmutz SM, Berryere TG, Ellinwood NM, Kerns JA, Barsh GS (2003) MC1R studies in dogs with melanistic mask or brindle patterns. J Hered 94:69\u201373","journal-title":"J Hered"},{"key":"9197_CR45","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1093\/genetics\/150.3.1177","volume":"150","author":"JMH Kijas","year":"1998","unstructured":"Kijas JMH, Wales R, Tornsten A, Chardon P, Moller M, Andersson L (1998) Melanocortin receptor 1 (MC1R) mutations and coast color in pigs. Genetics 150:1177\u20131185","journal-title":"Genetics"},{"key":"9197_CR46","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1093\/genetics\/158.2.779","volume":"158","author":"JMH Kijas","year":"2001","unstructured":"Kijas JMH, Moller M, Plastow G, Andersson L (2001) A frameshift mutation in MC1R and a high frequency of somatic reversions cause black spotting in pigs. Genetics 158:779\u2013785","journal-title":"Genetics"},{"key":"9197_CR47","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/0167-4781(96)00100-5","volume":"1308","author":"S Takeuchi","year":"1996","unstructured":"Takeuchi S, Suzuki H, Yabuuchi M, Takahashi S (1996). A possible involvement of melanocortin 1-receptor in regulating feather color pigmentation in the chicken. Biochim Biophys Acta 1308:164\u2013168","journal-title":"Biochim Biophys Acta"},{"key":"9197_CR48","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/S0960-9822(01)00158-0","volume":"11","author":"E Theron","year":"2001","unstructured":"Theron E, Hawkins K, Bermingham E, Ricklefs RE, Mundy NI (2001) The molecular basis of an avian plumage polymorphism in the wild: a melanocortin-1-receptor point mutation is perfectly associated with the melanic plumage morph of the bananaquit, Coereba flaveola. Curr Biol 11:550\u2013557","journal-title":"Curr Biol"},{"key":"9197_CR49","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1126\/science.1093834","volume":"303","author":"NI Mundy","year":"2004","unstructured":"Mundy NI, Badcock NS, Hart T, Scribner K, Janssen K, Nadeau NJ (2004) Conserved genetic basis of a quantitative plumage trait involved in mate choice. Science 303:1870\u20131873","journal-title":"Science"},{"key":"9197_CR50","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1365-2052.2006.01442.x","volume":"37","author":"NJ Nadeau","year":"2006","unstructured":"Nadeau NJ, Minvielle F, Mundy NI (2006) Association of a Glu92Lys substitution in MC1R with extended brown in Japanese quail (Coturnix japonica). Anim Genet 37:287\u2013289","journal-title":"Anim Genet"},{"key":"9197_CR51","doi-asserted-by":"crossref","first-page":"14006","DOI":"10.1074\/jbc.M413692200","volume":"280","author":"T Hoashi","year":"2005","unstructured":"Hoashi T, Watabe H, Muller J, Yamaguchi Y, Vieira WD, Hearing VJ (2005) MART-1 is required for the function of the melanosomal matrix protein PMEL17\/GP100 and the maturation of melanosomes. J Biol Chem 280:14006\u201314016","journal-title":"J Biol Chem"},{"key":"9197_CR52","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1034\/j.1600-0749.2001.140406.x","volume":"14","author":"J Voisey","year":"2001","unstructured":"Voisey J, Box NF, van Daal A (2001) A polymorphism study of the human Agouti gene and its association with MC1R. Pigment Cell Res 14:264\u2013267","journal-title":"Pigment Cell Res"},{"key":"9197_CR53","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1432-1033.1994.tb19922.x","volume":"219","author":"B Bouchard","year":"1994","unstructured":"Bouchard B, Del Marmol V, Jackson IJ, Cherif D, Dubertret L (1994) Molecular characterization of a human tyrosinase-related-protein-2 cDNA Patterns of expression in melanocytic cells. Eur J Biochem 219:127\u2013134","journal-title":"Eur J Biochem"},{"key":"9197_CR54","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1034\/j.1600-0749.2000.130506.x","volume":"13","author":"R Sarangarajan","year":"2000","unstructured":"Sarangarajan R, Zhao Y, Babcock G, Cornelius J, Lamoreux ML, Boissy RE (2000). Mutant alleles at the brown locus encoding tyrosinase-related protein-1 (TRP-1) affect proliferation of mouse melanocytes in culture. Pigment Cell Res 13:337\u2013344","journal-title":"Pigment Cell Res"},{"key":"9197_CR55","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1034\/j.1600-0749.2000.130510.x","volume":"13","author":"P Manga","year":"2000","unstructured":"Manga P, Sato K, Ye L, Beermann F, Lamoreux ML, Orlow SJ (2000) Mutational analysis of the modulation of tyrosinase by tyrosinase-related proteins 1 and 2 in vitro. Pigment Cell Res 13:364\u2013374","journal-title":"Pigment Cell Res"},{"key":"9197_CR56","doi-asserted-by":"crossref","unstructured":"Deng WD, Xi DM, Gou X, Yang SL, Shi XW, Mao HM (2007) Pigmentation in Black-boned sheep (Ovis aries): association with polymorphism of the Tyrosinase gene. Mol Biol Rep. doi:10.1007\/s11033-007-9097-z","DOI":"10.1007\/s11033-007-9097-z"},{"key":"9197_CR57","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0022-0728(94)03389-7","volume":"375","author":"JY Li","year":"1994","unstructured":"Li JY, Christensen BM (1994) Effect of pH on the oxidation pathway of dopamine and dopa. J Electroanal Chem 375:219\u2013231","journal-title":"J Electroanal Chem"},{"key":"9197_CR58","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1006\/excr.2000.5092","volume":"262","author":"BB Fuller","year":"2001","unstructured":"Fuller BB, Spaulding DT, Smith DR (2001) Regulation of the catalytic activity of preexisting tyrosinase in black and Caucasian human melanocyte cell cultures. Exp Cell Res 262: 197\u2013208","journal-title":"Exp Cell Res"},{"key":"9197_CR59","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.yexcr.2004.04.033","volume":"298","author":"DR Smith","year":"2004","unstructured":"Smith DR, Spaulding DT, Glenn HM, Fuller BB (2004) The relationship between Na+\/H+ exchanger expression and tyrosinese activeity in human melanocytes. Exp Cell Res 298:521\u2013534","journal-title":"Exp Cell Res"},{"key":"9197_CR60","doi-asserted-by":"crossref","first-page":"7971","DOI":"10.1074\/jbc.M309714200","volume":"279","author":"H Watabe","year":"2004","unstructured":"Watabe H, Valencia JC, Yasumoto K, Kushimoto T, Ando H, Muller J, Vieira WD, Mizoguchi M, Appella E, Hearing VJ (2004) Regulation of tyrosinase processing and trafficking by organellar pH and by proteasome activity. J Biol Chem 279:7971\u20137981","journal-title":"J Biol Chem"},{"key":"9197_CR61","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.exer.2005.08.013","volume":"82","author":"L Ni-Komatsu","year":"2006","unstructured":"Ni-Komatsu L, Orlow SJ (2006) Heterologous expression of tyrosinase recapitulates the misprocessing and mistrafficking in oculocutaneous albinism type 2: Effects of altering intracellular pH and pink-eyed dilution gene expression. Exp Eye Res 82:519\u2013528","journal-title":"Exp Eye Res"},{"key":"9197_CR62","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1097\/00008390-200510000-00006","volume":"15","author":"M Wolf","year":"2005","unstructured":"Wolf M, Bauder-Wust U, Haberkorn U, Mier W, Eisenhut M (2005) Alkylating benzamides with melanoma cytotoxicity: role of melanin, tyrosinase, intracellular pH and DNA interaction. Melanoma Res 15:383\u2013391","journal-title":"Melanoma Res"},{"key":"9197_CR63","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1126\/science.1116238","volume":"310","author":"RL Lamason","year":"2005","unstructured":"Lamason RL, Mohideen MA, Mest JR, Wong AC, Norton HL, Aros MC, Jurynec MJ, Mao X, Humphreville VR, Humbert JE, Sinha S, Moore JL, Jagadeeswaran P, Zhao W, Ning G, Makalowska I, McKeigue PM, O\u2019donnell D, Kittles R, Parra EJ, Mangini NJ, Grunwald DJ, Shriver MD, Canfield VA, Cheng KC (2005) SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans. Science 310:1782\u20131786","journal-title":"Science"},{"key":"9197_CR64","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1007\/s00414-006-0112-z","volume":"121","author":"M Soejima","year":"2007","unstructured":"Soejima M, Koda Y (2007) Population differences of two coding SNPs in pigmentation-related genes SLC24A5 and SLC45A2. Int J Legal Med 121:36\u201339","journal-title":"Int J Legal Med"},{"key":"9197_CR65","doi-asserted-by":"crossref","first-page":"10964","DOI":"10.1073\/pnas.0502856102","volume":"102","author":"S Chintala","year":"2005","unstructured":"Chintala S, Li W, Lamoreux ML, Ito S, Wakamatsu K, Sviderskaya EV, Bennett DC, Park YM, Gahl WA, Huizing M, Spritz RA, Ben S, Novak EK, Tan J, Swank RT (2005) Slc7a11 gene controls production of pheomelanin pigment and proliferation of cultured cells. Proc Natl Acad Sci USA 102:10964\u201310969","journal-title":"Proc Natl Acad Sci USA"},{"key":"9197_CR66","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jdermsci.2004.08.014","volume":"37","author":"VJ Hearing","year":"2005","unstructured":"Hearing VJ (2005) Biogenesis of pigment granules: a sensitive way to regulate melanocyte function. J Dermatol Sci 37:3\u201314","journal-title":"J Dermatol Sci"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-007-9197-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11033-007-9197-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-007-9197-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,30]],"date-time":"2021-08-30T12:29:48Z","timestamp":1630326588000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11033-007-9197-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,12,13]]},"references-count":66,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["9197"],"URL":"https:\/\/doi.org\/10.1007\/s11033-007-9197-9","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,12,13]]}}}