{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T03:17:12Z","timestamp":1789096632571,"version":"build-2803163510"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2012,2,5]],"date-time":"2012-02-05T00:00:00Z","timestamp":1328400000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2012,5]]},"DOI":"10.1007\/s11033-011-1424-8","type":"journal-article","created":{"date-parts":[[2012,2,4]],"date-time":"2012-02-04T16:16:26Z","timestamp":1328372186000},"page":"6095-6100","source":"Crossref","is-referenced-by-count":7,"title":["The indicative effect of Notch1 expression for the prognosis of T-cell acute lymphocytic leukemia: a systematic review"],"prefix":"10.1007","volume":"39","author":[{"given":"Jiexian","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,2,5]]},"reference":[{"key":"1424_CR1","doi-asserted-by":"crossref","first-page":"4243","DOI":"10.1182\/blood.V90.11.4243","volume":"90","author":"JH Kersey","year":"1997","unstructured":"Kersey JH (1997) Fifty years of studies of the biology and therapy of childhood leukemia. Blood 90:4243","journal-title":"Blood"},{"key":"1424_CR2","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1056\/NEJMra052603","volume":"354","author":"CH Pui","year":"2006","unstructured":"Pui CH, Evans WE (2006) Treatment of acute lymphoblastic leukemia. N Engl J Med 354:166\u2013178","journal-title":"N Engl J Med"},{"key":"1424_CR3","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1056\/NEJMra023001","volume":"350","author":"CH Pui","year":"2004","unstructured":"Pui CH, Relling MV, Downing JR (2004) Acute lymphoblastic leukemia. N Engl J Med 350:1535\u20131548","journal-title":"N Engl J Med"},{"key":"1424_CR4","doi-asserted-by":"crossref","first-page":"6306","DOI":"10.1200\/JCO.2005.05.047","volume":"23","author":"SA Armstrong","year":"2005","unstructured":"Armstrong SA, Look AT (2005) Molecular genetics of acute lymphoblastic leukemia. J Clin Oncol 23:6306\u20136315","journal-title":"J Clin Oncol"},{"key":"1424_CR5","first-page":"735","volume":"91","author":"FM Uckum","year":"1998","unstructured":"Uckum FM, Sensel MG, Sun L, Steinherz PG, Trigg ME, Heerema NA, Sather HN, Reaman GH, Gayon PS (1998) Biology and treatment of childhood T-lineage acute lymphoblastic leukemia. Blood 91:735\u2013746","journal-title":"Blood"},{"key":"1424_CR6","doi-asserted-by":"crossref","unstructured":"Hoelzer D, Gokbuget N, Ottmann O, et al (2002) Acute lymphoblastic leukemia. Hematology (Am Soc Hematol Educ Program) 2002:162\u201392","DOI":"10.1182\/asheducation-2002.1.162"},{"key":"1424_CR7","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1126\/science.278.5340.1059","volume":"278","author":"AT Look","year":"1997","unstructured":"Look AT (1997) Oncogenic transcription factors in the human acute leukemias. Science 278:1059\u20131064","journal-title":"Science"},{"key":"1424_CR8","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/ni1045","volume":"5","author":"F Radtke","year":"2004","unstructured":"Radtke F, Wilson A, Mancini SJ, MacDonald HR (2004) Notch regulation of lymphocyte development and function. Nat Immunol 5:247\u2013253","journal-title":"Nat Immunol"},{"key":"1424_CR9","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/0092-8674(91)90111-B","volume":"66","author":"LW Ellisen","year":"1991","unstructured":"Ellisen LW, Bird J, West DC et al (1991) TAN-1, the human homolog of the Drosophila notch gene is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66:649\u2013661","journal-title":"Cell"},{"key":"1424_CR10","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.1084\/jem.183.5.2283","volume":"183","author":"WS Pear","year":"1996","unstructured":"Pear WS, Aster JC, Scott ML et al (1996) Exclusive development of T-cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J Exp Med 183:2283\u20132291","journal-title":"J Exp Med"},{"key":"1424_CR11","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S1074-7613(00)80105-3","volume":"11","author":"JC Pui","year":"1999","unstructured":"Pui JC, Allman D, Xu L et al (1999) Notch1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity 11:299\u2013308","journal-title":"Immunity"},{"key":"1424_CR12","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1128\/MCB.23.2.655-664.2003","volume":"23","author":"AP Weng","year":"2003","unstructured":"Weng AP, Nam Y, Wolfe MS et al (2003) Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling. Mol Cell Biol 23:655\u2013664","journal-title":"Mol Cell Biol"},{"key":"1424_CR13","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1126\/science.1102160","volume":"306","author":"AP Weng","year":"2004","unstructured":"Weng AP, Ferrando AA, Lee W et al (2004) Activating mutations of NOTCH1 in human T-cell acute lymphoblastic leukemia. Science 306:269\u2013271","journal-title":"Science"},{"key":"1424_CR14","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1158\/1078-0432.CCR-05-2832","volume":"12","author":"YM Zhu","year":"2006","unstructured":"Zhu YM, Zhao WL, Fu JF, Shi JY, Pan Q, Hu J, Gao XD, Chen B, Li JM, Xiong SM, Gu LJ, Tang JY, Liang H, Jiang H, Xue YQ, Shen ZX, Chen Z, Chen SJ (2006) Notch mutations in T-cell acute lymphoblastic leukemia: prognostic significance and implication in multifactorial leukemogenesis. Clin Cancer Res 12:3043\u20133049","journal-title":"Clin Cancer Res"},{"key":"1424_CR15","doi-asserted-by":"crossref","first-page":"3918","DOI":"10.1182\/blood-2008-10-184069","volume":"113","author":"V Asnafi","year":"2009","unstructured":"Asnafi V, Buzyn A, Le Noir S, Baleydier F, Simon A, Beldjord K, Reman O, Witz F, Fagot T, Tavernier E, Turlure P, Leguay T, Huguet F, Vernant JP, Daniel F, Bene MC, Ifrah N, Thomas X, Dombret H, Macintyre E (2009) NOTCH1\/FBXW7 mutation identifies a large subgroup with favourable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): a GRAALL study. Blood 113:3918\u20133924","journal-title":"Blood"},{"key":"1424_CR16","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1038\/sj.leu.2404957","volume":"22","author":"M Grotel van","year":"2008","unstructured":"van Grotel M, Meijerink JPP, van Wering ER, Langerak AW, Beverloo HB, Buijs-Gladdines JGCAM, Burger NB, Passier M, van Lieshout EM, Kamps WA, Veerman AJP, van Noesel MM, Pieters R (2008) Prognostic significance of molecular-cytogenetic abnormalities in pediatric T-ALL is not explained by immunophenotypic differences. Leukemia 22:124\u2013131","journal-title":"Leukemia"},{"key":"1424_CR17","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1182\/blood-2005-12-4956","volume":"108","author":"S Breit","year":"2006","unstructured":"Breit S, Stanulla M, Flohr T, Schrappe M, Ludwig WD, Tolle G, Happich M, Muckenthaler MU, Kulozik AE (2006) Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia. Blood 108:1151\u20131157","journal-title":"Blood"},{"key":"1424_CR18","doi-asserted-by":"crossref","first-page":"5611","DOI":"10.1158\/0008-5472.CAN-06-4381","volume":"67","author":"A Malyukova","year":"2007","unstructured":"Malyukova A, Dohda T, von der Lehr N, Akhondi S, Corcoran M, Heyman M, Spruck C, Grander D, Lendahl U, Sangfelt O (2007) The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling. Cancer Res 67:5611\u20135616","journal-title":"Cancer Res"},{"key":"1424_CR19","doi-asserted-by":"crossref","first-page":"2815","DOI":"10.1002\/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0.CO;2-8","volume":"17","author":"MKB Parmar","year":"1998","unstructured":"Parmar MKB, Torri V, Stewart L (1998) Extracting summary statistics to perform meta-analysis of the published literature for survival endpoints. Stat Med 17:2815\u20132834","journal-title":"Stat Med"},{"key":"1424_CR20","first-page":"1212","volume":"91","author":"Martine Grotel van","year":"2006","unstructured":"van Martine Grotel, Jules PP, Meijerink H, Berna Beverloo, Anton W et al (2006) The outcome of molecular-cytogenetic subgroups in pediatric T-cell acute lymphoblastic leukemia: a retrospective study of patients treated according to DCOG or COALL protocols. Haematologica 91:1212\u20131221","journal-title":"Haematologica"},{"key":"1424_CR21","doi-asserted-by":"crossref","first-page":"5136","DOI":"10.1182\/blood-2009-08-231217","volume":"114","author":"DI Marks","year":"2009","unstructured":"Marks DI, Paietta EM, Anthony V et al (2009) Randomized prospective trial (UKALL XII\/ECOG 2993) immunophenotype, cytogenetics, and outcome from the large T-cell acute lymphoblastic leukemia in adults: clinical features. Blood 114:5136\u20135145","journal-title":"Blood"},{"issue":"8","key":"1424_CR22","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1038\/leu.2009.64","volume":"23","author":"AL Gedman","year":"2009","unstructured":"Gedman AL, Chen Q, Desmoulin SK et al (2009) The impact of NOTCH1, FBW7, PTEN mutations on prognosis, downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children\u2019s Oncology Group. Leukemia 23(8):1417\u20131425","journal-title":"Leukemia"},{"key":"1424_CR23","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1038\/leu.2010.205","volume":"24","author":"E Clappier","year":"2010","unstructured":"Clappier E, Collette S, Grardel N et al (2010) NOTCH1 and FBXW7 mutations have a favorable impact on early response to treatment, but not on outcome, in children with T-cell acute lymphoblastic leukemia (T-ALL) treated on EORTC trials 58881 and 58951. Leukemia 24:2023\u20132031","journal-title":"Leukemia"},{"key":"1424_CR24","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1038\/leu.2010.203","volume":"24","author":"C Kox","year":"2010","unstructured":"Kox C, Zimmermann M, Stanulla M et al (2010) The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL\u2013BFM 2000 protocol can be separated from FBXW7 loss of function. Leukemia 24:2005\u20132013","journal-title":"Leukemia"},{"key":"1424_CR25","doi-asserted-by":"crossref","unstructured":"Mansour MR, Sulis ML, Duke V et al (2009) Prognostic implications of NOTCH1 and FBXW7 mutations in adults with T-Cell acute lymphoblastic leukemia treated on the MRC UKALLXII\/ECOG E2993 protocol. J Clin Oncol 27:4352\u20134356","DOI":"10.1200\/JCO.2009.22.0996"},{"key":"1424_CR26","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1111\/j.1365-2141.2009.07607.x","volume":"145","author":"M-J Park","year":"2009","unstructured":"Park M-J, Taki T, Oda M et al (2009) FBXW7 and NOTCH1 mutations in childhood T-cell acute lymphoblastic leukaemia and T-cell non-Hodgkin lymphoma. Br J Haematol 145:198\u2013206","journal-title":"Br J Haematol"},{"key":"1424_CR27","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1038\/leu.2010.204","volume":"24","author":"L Zuurbier","year":"2010","unstructured":"Zuurbier L, Homminga I, Calvert V et al (2010) NOTCH1 and\/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols. Leukemia 24:2014\u20132022","journal-title":"Leukemia"},{"key":"1424_CR28","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1093\/oxfordjournals.aje.a000179","volume":"156","author":"J Little","year":"2002","unstructured":"Little J, Bradley L, Bray MS et al (2002) Reporting, appraising, and integrating data on genotype prevalence and gene-disease association. Am J Epidemiol 156:300\u2013310","journal-title":"Am J Epidemiol"},{"key":"1424_CR29","doi-asserted-by":"crossref","first-page":"3097","DOI":"10.1182\/blood-2004-03-1224","volume":"104","author":"BK Hadland","year":"2004","unstructured":"Hadland BK, Huppert SS, Kanungo J et al (2004) A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development. Blood 104:3097\u20133105","journal-title":"Blood"},{"key":"1424_CR30","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1182\/blood-2004-02-0514","volume":"104","author":"I Maillard","year":"2004","unstructured":"Maillard I, Weng AP, Carpenter AC et al (2004) Mastermind critically regulates Notch-mediated lymphoid cell fate decisions. Blood 104:1696\u20131702","journal-title":"Blood"},{"key":"1424_CR31","doi-asserted-by":"crossref","first-page":"R129","DOI":"10.1016\/S0960-9822(04)00038-7","volume":"14","author":"F Schweisguth","year":"2004","unstructured":"Schweisguth F (2004) Notch signaling activity. Curr Biol 14:R129\u2013R138","journal-title":"Curr Biol"},{"key":"1424_CR32","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1101\/gad.991602","volume":"16","author":"CJ Fryer","year":"2002","unstructured":"Fryer CJ, Lamar E, Turbachova I, Kintner C, Jones KA (2002) Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex. Genes Dev 16:1397\u20131411","journal-title":"Genes Dev"},{"key":"1424_CR33","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.semcancer.2004.04.012","volume":"14","author":"PA Zweidler-McKay","year":"2004","unstructured":"Zweidler-McKay PA, Pear WS (2004) Notch and T-cell malignancy. Semin Cancer Biol 14:329\u2013340","journal-title":"Semin Cancer Biol"},{"key":"1424_CR34","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/ng1071","volume":"33","author":"KE Lohmueller","year":"2003","unstructured":"Lohmueller KE, Pearce CL, Pike M et al (2003) Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 33:177\u2013182","journal-title":"Nat Genet"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-011-1424-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11033-011-1424-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-011-1424-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T18:50:57Z","timestamp":1593629457000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11033-011-1424-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2,5]]},"references-count":34,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,5]]}},"alternative-id":["1424"],"URL":"https:\/\/doi.org\/10.1007\/s11033-011-1424-8","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,2,5]]}}}