{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:59:45Z","timestamp":1762505985915},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2012,10,11]],"date-time":"2012-10-11T00:00:00Z","timestamp":1349913600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1007\/s11033-012-2091-0","type":"journal-article","created":{"date-parts":[[2012,10,11]],"date-time":"2012-10-11T10:33:03Z","timestamp":1349951583000},"page":"545-552","source":"Crossref","is-referenced-by-count":11,"title":["Genetic analysis of the 3\u2032 untranslated region of the bovine SLC11A1 gene reveals novel polymorphisms"],"prefix":"10.1007","volume":"40","author":[{"given":"F. C.","family":"Hasenauer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. E.","family":"Caffaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Czibener","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Comerci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. A.","family":"Poli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. A.","family":"Rossetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,10,11]]},"reference":[{"key":"2091_CR1","first-page":"144","volume-title":"Advances in brucellosis research: an international symposium","author":"JW Templeton","year":"1990","unstructured":"Templeton JW, Adams LG (1990) Natural resistance to bovine brucellosis. In: Adams LG (ed) Advances in brucellosis research: an international symposium. Texas A&M University Press, College Station, TX, pp 144\u2013150"},{"key":"2091_CR2","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1084\/jem.182.3.655","volume":"182","author":"S Vidal","year":"1995","unstructured":"Vidal S, Tremblay ML, Govoni G, Gauthier S, Sebastiani G, Malo D, Skamene E, Olivier M, Jothy S, Gros P (1995) The Ity\/Lsh\/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene. J Exp Med 182:655\u2013666","journal-title":"J Exp Med"},{"key":"2091_CR3","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0168-9525(96)30042-5","volume":"12","author":"M Cellier","year":"1996","unstructured":"Cellier M, Belouchi A, Groset P (1996) Resistance to intracellular infections: comparative genomic analysis of Nramp. Trends Genet 12:201\u2013204","journal-title":"Trends Genet"},{"key":"2091_CR4","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1128\/IAI.74.4.2115-2120.2006","volume":"74","author":"G Borriello","year":"2006","unstructured":"Borriello G, Capparelli R, Bianco M, Fenizia D, Alfano F, Capuano F, Ercolini D, Parisi A, Roperto S, Iannelli D (2006) Genetic resistance to Brucella abortus in the water buffalo (Bubalus bubalis). Infect Immun 74:2115\u20132120","journal-title":"Infect Immun"},{"key":"2091_CR5","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1128\/IAI.00948-06","volume":"75","author":"R Capparelli","year":"2007","unstructured":"Capparelli R, Alfano F, Amoroso MG, Borriello G, Fenizia D, Bianco A, Roperto S, Roperto F, Iannelli D (2007) Protective effect of the Nramp1 BB genotype against Brucella abortus in the water buffalo (Bubalus bubalis). Infect Immun 75:988\u2013996","journal-title":"Infect Immun"},{"key":"2091_CR6","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1590\/S1415-47572010000300014","volume":"33","author":"R Martinez","year":"2010","unstructured":"Martinez R, Dunner S, Toro R, Tobon J, Gallego J, Canon J (2010) Effect of polymorphisms in the Slc11a1 coding region on resistance to brucellosis by macrophages in vitro and after challenge in two Bos breeds (Blanco Orejinegro and Zebu). Genet Mol Biol 33:463\u2013470","journal-title":"Genet Mol Biol"},{"key":"2091_CR7","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1439-0388.2008.00727.x","volume":"125","author":"R Martinez","year":"2008","unstructured":"Martinez R, Toro R, Montoya F, Burbano M, Tobon J, Gallego J, Dunner S, Canon J (2008) Bovine SLC11A1 3\u2032 UTR SSCP genotype evaluated by a macrophage in vitro killing assay employing a Brucella abortus strain. J Anim Breed Genet 125:271\u2013279","journal-title":"J Anim Breed Genet"},{"key":"2091_CR8","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1111\/j.1365-2052.2011.02203.x","volume":"42","author":"HN Kadarmideen","year":"2011","unstructured":"Kadarmideen HN, Ali AA, Thomson PC, Muller B, Zinsstag J (2011) Polymorphisms of the SLC11A1 gene and resistance to bovine tuberculosis in African Zebu cattle. Anim Genet 42:656\u2013658","journal-title":"Anim Genet"},{"key":"2091_CR9","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S1369-5274(99)00049-1","volume":"3","author":"S Gruenheid","year":"2000","unstructured":"Gruenheid S, Gros P (2000) Genetic susceptibility to intracellular infections: Nramp1, macrophage function and divalent cations transport. Curr Opin Microbiol 3:43\u201348","journal-title":"Curr Opin Microbiol"},{"key":"2091_CR10","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0165-2478(98)00127-8","volume":"65","author":"JM Blackwell","year":"1999","unstructured":"Blackwell JM, Searle S (1999) Genetic regulation of macrophage activation: understanding the function of Nramp1 (=Ity\/Lsh\/Bcg). Immunol Lett 65:73\u201380","journal-title":"Immunol Lett"},{"key":"2091_CR11","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1128\/IAI.67.3.1386-1392.1999","volume":"67","author":"BS Zwilling","year":"1999","unstructured":"Zwilling BS, Kuhn DE, Wikoff L, Brown D, Lafuse W (1999) Role of iron in Nramp1-mediated inhibition of mycobacterial growth. Infect Immun 67:1386\u20131392","journal-title":"Infect Immun"},{"key":"2091_CR12","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1042\/0264-6021:3630089","volume":"363","author":"V Mulero","year":"2002","unstructured":"Mulero V, Searle S, Blackwell JM, Brock JH (2002) Solute carrier 11a1 (Slc11a1; formerly Nramp1) regulates metabolism and release of iron acquired by phagocytic, but not transferrin-receptor-mediated, iron uptake. Biochem J 363:89\u201394","journal-title":"Biochem J"},{"key":"2091_CR13","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S1286-4579(02)01548-4","volume":"4","author":"S Wyllie","year":"2002","unstructured":"Wyllie S, Seu P, Goss JA (2002) The natural resistance-associated macrophage protein 1 Slc11a1 (formerly Nramp1) and iron metabolism in macrophages. Microbes Infect 4:351\u2013359","journal-title":"Microbes Infect"},{"key":"2091_CR14","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1101\/gr.6.10.956","volume":"6","author":"J Feng","year":"1996","unstructured":"Feng J, Li Y, Hashad M, Schurr E, Gros P, Adams LG, Templeton J (1996) Bovine natural resistance associated macrophage protein 1 (Nramp1) gene. Genome Res 6:956\u2013964","journal-title":"Genome Res"},{"key":"2091_CR15","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1046\/j.1365-2370.1999.00148.x","volume":"26","author":"P Horin","year":"1999","unstructured":"Horin P, Rychlik I, Templeton JW, Adams LG (1999) A complex pattern of microsatellite polymorphism within the bovine NRAMP1 gene. Eur J Immunogenet 26:311\u2013313","journal-title":"Eur J Immunogenet"},{"key":"2091_CR16","first-page":"11","volume":"19","author":"JP Gonzalez","year":"2006","unstructured":"Gonzalez JP, Saldarriaga OA, L\u00f3pez-Herrera A, Bermudez NR, Wildeman Zapata B, Ossa J, Rugeles MT, Bedoya G (2006) Polymorphism in 1908STR1934 locus of the Nramp1 bovine gene in eight cattle breeds. Rev Col Cienc Pec 19:11\u201317","journal-title":"Rev Col Cienc Pec"},{"key":"2091_CR17","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.vetimm.2005.07.018","volume":"109","author":"TA Paixao","year":"2006","unstructured":"Paixao TA, Ferreira C, Borges AM, Oliveira DA, Lage AP, Santos RL (2006) Frequency of bovine Nramp1 (Slc11a1) alleles in Holstein and Zebu breeds. Vet Immunol Immunopathol 109:37\u201342","journal-title":"Vet Immunol Immunopathol"},{"key":"2091_CR18","volume-title":"Molecular cloning: a laboratory manual","author":"J Sambrook","year":"1989","unstructured":"Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor Laboratory Press, New York","edition":"2"},{"key":"2091_CR19","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1007\/s11033-010-0275-z","volume":"38","author":"PP Iglesias","year":"2010","unstructured":"Iglesias PP, Caffaro ME, Amadio AF, Arias Manotti A, Poli MA (2010) CAPN1 markers in three Argentinean cattle breeds: report of a new InDel polymorphism within intron 17. Mol Biol Rep 38:1645\u20131649","journal-title":"Mol Biol Rep"},{"key":"2091_CR20","first-page":"365","volume":"132","author":"S Rozen","year":"2000","unstructured":"Rozen S, Skaletsky H (2000) Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol 132:365\u2013386","journal-title":"Methods Mol Biol"},{"key":"2091_CR21","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.2460\/ajvr.2000.61.1140","volume":"61","author":"R Barthel","year":"2000","unstructured":"Barthel R, Piedrahita JA, McMurray DN, Payeur J, Baca D, Suarez Guemes F, Perumaalla VS, Ficht TA, Templeton JW, Adams LG (2000) Pathologic findings and association of Mycobacterium bovis infection with the bovine NRAMP1 gene in cattle from herds with naturally occurring tuberculosis. Am J Vet Res 61:1140\u20131144","journal-title":"Am J Vet Res"},{"key":"2091_CR22","unstructured":"Hall TA (1999) BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95\/98\/NT. Nucleic Acids Symposium 41:95\u201398"},{"key":"2091_CR23","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1093\/oxfordjournals.jhered.a111573","volume":"86","author":"M Raymond","year":"1995","unstructured":"Raymond M, Rousset F (1995) GENEPOP (version 1.2): population genetics software for exact tests and ecumenicism. J Hered 86:248\u2013249","journal-title":"J Hered"},{"key":"2091_CR24","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1111\/j.1755-0998.2010.02847.x","volume":"10","author":"L Excoffier","year":"2010","unstructured":"Excoffier L, Lischer HE (2010) Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol Ecol Resour 10:564\u2013567","journal-title":"Mol Ecol Resour"},{"key":"2091_CR25","unstructured":"Park SDE (2001) Trypanotolerance in West African cattle and the population genetics effects of selection. Trinity College. University of Dublin, Dublin"},{"key":"2091_CR26","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0165-2427(95)05492-8","volume":"50","author":"T Qureshi","year":"1996","unstructured":"Qureshi T, Templeton JW, Adams LG (1996) Intracellular survival of Brucella abortus, Mycobacterium bovis BCG, Salmonella dublin, and Salmonella typhimurium in macrophages from cattle genetically resistant to Brucella abortus. Vet Immunol Immunopathol 50:55\u201365","journal-title":"Vet Immunol Immunopathol"},{"key":"2091_CR27","doi-asserted-by":"crossref","first-page":"3110","DOI":"10.1128\/IAI.69.5.3110-3119.2001","volume":"69","author":"R Barthel","year":"2001","unstructured":"Barthel R, Feng J, Piedrahita JA, McMurray DN, Templeton JW, Adams LG (2001) Stable transfection of the bovine NRAMP1 gene into murine RAW264.7 cells: effect on Brucella abortus survival. Infect Immun 69:3110\u20133119","journal-title":"Infect Immun"},{"key":"2091_CR28","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.vetmic.2005.09.012","volume":"111","author":"N Kumar","year":"2005","unstructured":"Kumar N, Mitra A, Ganguly I, Singh R, Deb SM, Srivastava SK, Sharma A (2005) Lack of association of brucellosis resistance with (GT) (13) microsatellite allele at 3\u2032UTR of NRAMP1 gene in Indian zebu (Bos indicus) and crossbred (Bos indicus\u00a0\u00d7\u00a0Bos taurus) cattle. Vet Microbiol 111:139\u2013143","journal-title":"Vet Microbiol"},{"key":"2091_CR29","doi-asserted-by":"crossref","first-page":"200","DOI":"10.20506\/rst.17.1.1085","volume":"17","author":"LG Adams","year":"1998","unstructured":"Adams LG, Templeton JW (1998) Genetic resistance to bacterial diseases of animals. Rev Sci Tech 17:200\u2013219","journal-title":"Rev Sci Tech"},{"key":"2091_CR30","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.1128\/IAI.01855-06","volume":"75","author":"TA Paixao","year":"2007","unstructured":"Paixao TA, Poester FP, Carvalho Neta AV, Borges AM, Lage AP, Santos RL (2007) NRAMP1 3\u2032 untranslated region polymorphisms are not associated with natural resistance to Brucella abortus in cattle. Infect Immun 75:2493\u20132499","journal-title":"Infect Immun"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-012-2091-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11033-012-2091-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-012-2091-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T17:40:53Z","timestamp":1594748453000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11033-012-2091-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,11]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["2091"],"URL":"https:\/\/doi.org\/10.1007\/s11033-012-2091-0","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,11]]}}}