{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T05:48:26Z","timestamp":1766382506821},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2013,5,7]],"date-time":"2013-05-07T00:00:00Z","timestamp":1367884800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1007\/s11033-013-2538-y","type":"journal-article","created":{"date-parts":[[2013,5,6]],"date-time":"2013-05-06T15:18:08Z","timestamp":1367853488000},"page":"4465-4472","source":"Crossref","is-referenced-by-count":13,"title":["Bone morphogenetic proteins (BMPs) expression in the femoral heads of patients with avascular necrosis"],"prefix":"10.1007","volume":"40","author":[{"given":"Stavroula","family":"Samara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoe","family":"Dailiana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sokratis","family":"Varitimidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christos","family":"Chassanidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodora","family":"Koromila","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos N.","family":"Malizos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panagoula","family":"Kollia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,5,7]]},"reference":[{"issue":"Suppl 3","key":"2538_CR1","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1046\/j.1365-2362.2000.00621.x","volume":"30","author":"C Zalavras","year":"2000","unstructured":"Zalavras C, Dailiana Z, Elisaf M, Bairaktari E, Vlachogiannopoulos P, Katsaraki A, Malizos KN (2000) Potential aetiological factors concerning the development of osteonecrosis of the femoral head. Eur J Clin Invest 30(Suppl 3):215\u2013221","journal-title":"Eur J Clin Invest"},{"key":"2538_CR2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00256-007-0395-2","volume":"37","author":"G Hadjigeorgiou","year":"2008","unstructured":"Hadjigeorgiou G, Dardiotis E, Dardioti M, Karantanas A, Dimitroulias A, Malizos K (2008) Genetic association studies in osteonecrosis of the femoral head. Skelet Radiol 37:1\u20137","journal-title":"Skelet Radiol"},{"key":"2538_CR3","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1097\/00003086-200105000-00016","volume":"386","author":"P Soucacos","year":"2001","unstructured":"Soucacos P, Beris A, Malizos K, Koropilias A, Zalavras H, Dailiana Z (2001) Treatment of avascular necrosis of the femoral head with vascularized fibular transplant. Clin Orthop Relat Res 386:120\u2013130","journal-title":"Clin Orthop Relat Res"},{"key":"2538_CR4","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/00003086-200105000-00004","volume":"386","author":"CJ Glueck","year":"2001","unstructured":"Glueck CJ, Freiberg RA, Fontaine RN, Tracy T, Wang P (2001) Hypofibrinolysis, thrombophilia, osteonecrosis. Clin Orthop Relat Res 386:19\u201333","journal-title":"Clin Orthop Relat Res"},{"issue":"1","key":"2538_CR5","first-page":"111","volume":"87","author":"GC Zalavras","year":"2002","unstructured":"Zalavras GC, Malizos K, Dokou E, Vartholomatos G (2002) The 677C\u00a0\u2192\u00a0T mutation of the methylene-tetrahydrofolate reductase gene in the pathogenesis of osteonecrosis of the femoral head. Hematologica 87(1):111\u2013112","journal-title":"Hematologica"},{"issue":"2","key":"2538_CR6","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.transproceed.2005.12.062","volume":"38","author":"A Celik","year":"2006","unstructured":"Celik A, Tekis D, Saglam F, Tunali S, Kabakci N, Ozaksoy D, Manisali M, Ozcan MA, Meral M, G\u00fclay H, Camsari T (2006) Association of corticosteroids and factor V, prothrombin, and MTHFR gene mutations with avascular osteonecrosis in renal allograft recipients. Transplant Proc 38(2):512\u2013516","journal-title":"Transplant Proc"},{"key":"2538_CR7","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/00003086-199909000-00017","volume":"366","author":"CJ Glueck","year":"1999","unstructured":"Glueck CJ, Fontaine RN, Gruppo R, Stroop D, Sieve-Smith L, Tracy T, Wang P (1999) The plasminogen activator inhibitor-1 gene, hypofibrinolysis and osteonecrosis. Clin Orthop Relat Res 366:133\u2013146","journal-title":"Clin Orthop Relat Res"},{"issue":"1","key":"2538_CR8","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/ajh.20311","volume":"79","author":"A Adekile","year":"2005","unstructured":"Adekile A, Haider MZ, Marouf R, Adekile AD (2005) HLA-DRB1 alleles in Hb SS patients with avascular necrosis of the femoral head. Am J Hematol 79(1):8\u201310","journal-title":"Am J Hematol"},{"issue":"Suppl 3","key":"2538_CR9","doi-asserted-by":"crossref","first-page":"82","DOI":"10.2106\/00004623-200300003-00014","volume":"85A","author":"TA Einhorn","year":"2003","unstructured":"Einhorn TA (2003) Clinical applications of recombinant human BMPs early experience and future development. J Bone Joint Surg Am 85A(Suppl 3):82\u201388","journal-title":"J Bone Joint Surg Am"},{"key":"2538_CR10","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1007\/s00264-005-0045-z","volume":"30","author":"R Bilic","year":"2006","unstructured":"Bilic R, Simic P, Jelic M, Stern-Padovan R, Dodig D (2006) Osteogenic protein-1 (BMP-7) accelerates healing of scaphoid non-union with proximal pole sclerosis. Int Orthop 30:128\u2013134","journal-title":"Int Orthop"},{"key":"2538_CR11","first-page":"210","volume":"13","author":"JR Bowers","year":"2004","unstructured":"Bowers JR, Dailiana ZH, McCarthy EF, Urbaniak JR (2004) Drug therapy increases bone density in osteonecrosis of the femoral head in canines. J Surg Orthop Adv 13:210\u2013216","journal-title":"J Surg Orthop Adv"},{"key":"2538_CR12","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1126\/science.150.3698.893","volume":"150","author":"MR Urist","year":"1965","unstructured":"Urist MR (1965) Bone: formation by autoinduction. Science 150:893\u2013899","journal-title":"Science"},{"issue":"4","key":"2538_CR13","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1080\/08977190412331279890","volume":"22","author":"DI Chen","year":"2004","unstructured":"Chen DI, Zhao M, Mundy GR (2004) Bone morphogenetic proteins. Growth Factors 22(4):233\u2013241","journal-title":"Growth Factors"},{"key":"2538_CR14","first-page":"26","volume":"346","author":"JM Wonzey","year":"1998","unstructured":"Wonzey JM, Rosen V (1998) Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair. Clin Orthop Relat Res 346:26\u201337","journal-title":"Clin Orthop Relat Res"},{"issue":"2","key":"2538_CR15","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1161\/01.RES.00000175571.53833.6c","volume":"97","author":"KA Hruska","year":"2005","unstructured":"Hruska KA, Mathew S, Saab G (2005) Bone morphogenetic proteins in vascular calcification. Circ Res 97(2):105\u2013114","journal-title":"Circ Res"},{"key":"2538_CR16","doi-asserted-by":"crossref","first-page":"82","DOI":"10.2106\/00004623-200300003-00014","volume":"85A","author":"T Enhorn","year":"2003","unstructured":"Enhorn T (2003) Clinical applications of recombinant human BMPs: early experience and future development. J Bone Joint Surg 85A:82\u201388","journal-title":"J Bone Joint Surg"},{"key":"2538_CR17","first-page":"43","volume":"8","author":"P Biase De","year":"2007","unstructured":"De Biase P, Capanna R (2007) Bone morphogenetic proteins and growth factors: emerging role in regenerative orthopaedic surgery. Injury 8:43\u201348","journal-title":"Injury"},{"key":"2538_CR18","first-page":"79","volume":"5","author":"JWM Gardeniers","year":"1993","unstructured":"Gardeniers JWM (1993) ARCO committee of technology and staging (Report on the committee meeting at Santiago ode Combostella). ARCO Newslett 5:79\u201382","journal-title":"ARCO Newslett"},{"issue":"1","key":"2538_CR19","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1385\/MB:23:1:37","volume":"23","author":"R Tuli","year":"2003","unstructured":"Tuli R, Seghatolescami MR, Tuli S, Wang ML, Hozack WJ, Manner PA, Danielson KG, Tuan RS (2003) A simple high-yield method for obtaining multipotential mesenchymal progenitor cells from trabecular bone. Mol Biotechnol 23(1):37\u201349","journal-title":"Mol Biotechnol"},{"issue":"2","key":"2538_CR20","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1210\/er.2002-0023","volume":"24","author":"E Canalis","year":"2003","unstructured":"Canalis E, Econimides AN, Gazzero E (2003) Bone morphogenetic protein, their antagonists, and the skeleton. Endocr Rev 24(2):218\u2013235","journal-title":"Endocr Rev"},{"issue":"8","key":"2538_CR21","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.2106\/00004623-200308000-00017","volume":"85A","author":"H Cheng","year":"2003","unstructured":"Cheng H, Jiang W, Phillips FM, Haydon RC, Peng Y, Zhou L, Luu HH, AN N, Breyer B, Vanichakarn P, Szatkowski JP, Park JY, He T-C (2003) Osteogenic activity of fourteen types of human bone morhpogenetic proteins (BMPs). J Bone Joint Surg Am 85A(8):1544\u20131552","journal-title":"J Bone Joint Surg Am"},{"issue":"12","key":"2538_CR22","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1016\/S1357-2725(96)00075-1","volume":"28","author":"LM Leong","year":"1996","unstructured":"Leong LM, Brickell PM (1996) Bone morphogenetic protein-4. Int J Biochem Cell Biol 28(12):1293\u20131296","journal-title":"Int J Biochem Cell Biol"},{"key":"2538_CR23","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1101\/gad.9.17.2105","volume":"9","author":"G Winnier","year":"1995","unstructured":"Winnier G, Blessing M, Labosky PA, Hogan BLM (1995) Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev 9:2105\u20132116","journal-title":"Genes Dev"},{"key":"2538_CR24","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/(SICI)1520-6408(1998)22:4<321::AID-DVG3>3.0.CO;2-8","volume":"22","author":"MJ Solloway","year":"1998","unstructured":"Solloway MJ, Dudley AT, Bikoff EK, Lyons KM, Hogan BL, Robertson EJ (1998) Mice lacking BMP-6 function. Dev Genet 22:321\u2013339","journal-title":"Dev Genet"},{"key":"2538_CR25","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1002\/jor.21144","volume":"28","author":"A Wutzl","year":"2010","unstructured":"Wutzl A, Rauner M, Seemann R, Millesi W, Krepler P, Pietschmann P, Ewers R (2010) Bone morphogenetic proteins 2, 5, and 6 in combination stimulate osteoblasts but not osteoclasts in vitro. JOR 28:1431\u20131439","journal-title":"JOR"},{"issue":"44","key":"2538_CR26","doi-asserted-by":"crossref","first-page":"3866","DOI":"10.1038\/onc.2009.257","volume":"28","author":"A Seckinger","year":"2009","unstructured":"Seckinger A, Meissner T, Moreaux J, Goldschmidt H, Fuhler GM, Benner A, Hundemer M, R\u00e8me T, Shaughnessy JD, Barlogie B, Bertsch U, Hillengass J, Ho AD, Pantesco V, Jauch A, Vos JD, Rossi JF, M\u00f6hler T, Klein B, Hose D (2009) Bone morphogenic protein 6: a member of a novel class of prognostic factors expressed by normal and malignant plasma cells inhibiting proliferation and angiogenesis. Oncogene 28(44):3866\u20133879","journal-title":"Oncogene"},{"key":"2538_CR27","doi-asserted-by":"crossref","first-page":"2977","DOI":"10.1242\/dev.122.10.2977","volume":"122","author":"H Zhang","year":"1996","unstructured":"Zhang H, Bradley A (1996) Mice deficient for BMP2 are nonviable and have defects in amnion\/chorion and cardiac development. Development 122:2977\u20132986","journal-title":"Development"},{"key":"2538_CR28","doi-asserted-by":"crossref","first-page":"2808","DOI":"10.1101\/gad.9.22.2808","volume":"9","author":"G Luo","year":"1995","unstructured":"Luo G, Hofman C, Bronckers AL, Sohocki M, Bradley A, Karsenty G (1995) BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning. Genes Dev 9:2808\u20132820","journal-title":"Genes Dev"},{"key":"2538_CR29","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1002\/(SICI)1097-0177(199703)208:3<349::AID-AJA6>3.0.CO;2-I","volume":"208","author":"AT Dudley","year":"1997","unstructured":"Dudley AT, Robertson EJ (1997) Overlapping expression domains of bone morphogenetic protein family members potentially account for limited tissue defects in BMP7 deficient embryos. Dev Dyn 208:349\u2013362","journal-title":"Dev Dyn"},{"issue":"3","key":"2538_CR30","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.bbrc.2003.08.058","volume":"309","author":"MH Lee","year":"2003","unstructured":"Lee MH, Kwon TG, Park HS, Wozney JM, Ryoo HM (2003) BMP-2-induced Osterix expression is mediated by Dlx5 but is independent of Runx2. Biochem Biophys Res Commun 309(3):689\u2013694","journal-title":"Biochem Biophys Res Commun"},{"issue":"2","key":"2538_CR31","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1172\/JCI33612","volume":"118","author":"S Khosla","year":"2008","unstructured":"Khosla S, Westendorf JJ, Oursler MJ (2008) Building bone to reverse osteoporosis and repair fractures. J Clin Invest 118(2):421\u2013428","journal-title":"J Clin Invest"},{"issue":"12","key":"2538_CR32","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1016\/j.addr.2012.03.014","volume":"64","author":"KW Lo","year":"2012","unstructured":"Lo KW, Ulery BD, Ashe KM, Laurencin CT (2012) Studies of bone morphogenetic protein-based surgical repair. Adv Drug Deliv Rev 64(12):1277\u20131291","journal-title":"Adv Drug Deliv Rev"},{"key":"2538_CR33","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1097\/01.blo.0000096826.67494.38","volume":"417","author":"MA Mont","year":"2003","unstructured":"Mont MA, Etienne G, Ragland PS (2003) Outcome of nonvascularized bone grafting for osteonecrosis of the femoral head. Clin Orthop Relat Res 417:84\u201392","journal-title":"Clin Orthop Relat Res"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-013-2538-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11033-013-2538-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-013-2538-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T14:28:29Z","timestamp":1688221709000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11033-013-2538-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,7]]},"references-count":33,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["2538"],"URL":"https:\/\/doi.org\/10.1007\/s11033-013-2538-y","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,7]]}}}