{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T11:09:21Z","timestamp":1770980961745,"version":"3.50.1"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2013,9,25]],"date-time":"2013-09-25T00:00:00Z","timestamp":1380067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1007\/s11033-013-2743-8","type":"journal-article","created":{"date-parts":[[2013,9,25]],"date-time":"2013-09-25T01:03:28Z","timestamp":1380071008000},"page":"6303-6308","source":"Crossref","is-referenced-by-count":26,"title":["MMP-2, TNF-\u03b1 and NLRP1 polymorphisms in Chinese patients with ankylosing spondylitis and rheumatoid arthritis"],"prefix":"10.1007","volume":"40","author":[{"given":"Rongbin","family":"Sun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruiping","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,9,25]]},"reference":[{"key":"2743_CR1","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/S0140-6736(07)60635-7","volume":"369","author":"J Braun","year":"2007","unstructured":"Braun J, Sieper J (2007) Ankylosing spondylitis. Lancet 369:1379\u20131390","journal-title":"Lancet"},{"key":"2743_CR2","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1056\/NEJMoa073491","volume":"357","author":"RM Plenge","year":"2007","unstructured":"Plenge RM, Seielstad M, Padyukov L et al (2007) TRAF1-C5 as a risk locus for rheumatoid arthritis\u2014a genomewide study. N Engl J Med 357:1199\u20131209","journal-title":"N Engl J Med"},{"key":"2743_CR3","first-page":"335","volume":"22","author":"G Giannelli","year":"2004","unstructured":"Giannelli G, Erriquez R, Iannone F et al (2004) MMP-2, MMP-9, TIMP-1 and TIMP-2 levels in patients with rheumatoid arthritis and psoriatic arthritis. Clin Exp Rheumatol 22:335\u2013338","journal-title":"Clin Exp Rheumatol"},{"key":"2743_CR4","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/nri1418","volume":"4","author":"WC Parks","year":"2004","unstructured":"Parks WC, Wilson CL, Lopez-Boado YS (2004) Matrix metalloproteinases as modulators of inflammation and innate immunity. Nat Rev Immunol 4:617\u2013629","journal-title":"Nat Rev Immunol"},{"key":"2743_CR5","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.gene.2009.01.002","volume":"435","author":"H Huang","year":"2009","unstructured":"Huang H, Zhao W, Tang Z et al (2009) Characterization of porcine MMP-2 and its association with immune traits. Gene 435:63\u201371","journal-title":"Gene"},{"key":"2743_CR6","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1136\/ard.59.6.455","volume":"59","author":"Y Yoshihara","year":"2000","unstructured":"Yoshihara Y, Nakamura H, Obata K et al (2000) Matrix metalloproteinases and tissue inhibitors of metalloproteinases in synovial fluids from patients with rheumatoid arthritis or osteoarthritis. Ann Rheum Dis 59:455\u2013461","journal-title":"Ann Rheum Dis"},{"key":"2743_CR7","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1136\/ard.58.11.691","volume":"58","author":"YT Konttinen","year":"1999","unstructured":"Konttinen YT, Ainola M, Valleala H et al (1999) Analysis of 16 different matrix metalloproteinases (MMP-1 to MMP-20) in the synovial membrane: different profiles in trauma and rheumatoid arthritis. Ann Rheum Dis 58:691\u2013697","journal-title":"Ann Rheum Dis"},{"key":"2743_CR8","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1136\/annrheumdis-2011-200867","volume":"71","author":"A Hot","year":"2012","unstructured":"Hot A, Zrioual S, Lenief V, Miossec P (2012) IL-17 and tumour necrosis factor alpha combination induces a HIF-1alpha-dependent invasive phenotype in synoviocytes. Ann Rheum Dis 71:1393\u20131401","journal-title":"Ann Rheum Dis"},{"key":"2743_CR9","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.4049\/jimmunol.169.5.2643","volume":"169","author":"T Itoh","year":"2002","unstructured":"Itoh T, Matsuda H, Tanioka M et al (2002) The role of matrix metalloproteinase-2 and matrix metalloproteinase-9 in antibody-induced arthritis. J Immunol 169:2643\u20132647","journal-title":"J Immunol"},{"key":"2743_CR10","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/ni773","volume":"3","author":"DB Corry","year":"2002","unstructured":"Corry DB, Rishi K, Kanellis J et al (2002) Decreased allergic lung inflammatory cell egression and increased susceptibility to asphyxiation in MMP2-deficiency. Nat Immunol 3:347\u2013353","journal-title":"Nat Immunol"},{"key":"2743_CR11","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.molimm.2012.08.018","volume":"53","author":"G Li","year":"2013","unstructured":"Li G, Zhang Y, Qian Y et al (2013) Interleukin-17A promotes rheumatoid arthritis synoviocytes migration and invasion under hypoxia by increasing MMP2 and MMP9 expression through NF-kappaB\/HIF-1alpha pathway. Mol Immunol 53:227\u2013236","journal-title":"Mol Immunol"},{"key":"2743_CR12","doi-asserted-by":"crossref","first-page":"7549","DOI":"10.1074\/jbc.M010242200","volume":"276","author":"SJ Price","year":"2001","unstructured":"Price SJ, Greaves DR, Watkins H (2001) Identification of novel, functional genetic variants in the human matrix metalloproteinase-2 gene: role of Sp1 in allele-specific transcriptional regulation. J Biol Chem 276:7549\u20137558","journal-title":"J Biol Chem"},{"key":"2743_CR13","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.clinbiochem.2008.04.012","volume":"41","author":"YH Chang","year":"2008","unstructured":"Chang YH, Lin IL, Tsay GJ et al (2008) Elevated circulatory MMP-2 and MMP-9 levels and activities in patients with rheumatoid arthritis and systemic lupus erythematosus. Clin Biochem 41:955\u2013959","journal-title":"Clin Biochem"},{"key":"2743_CR14","first-page":"107","volume":"29","author":"CA Hitchon","year":"2002","unstructured":"Hitchon CA, Danning CL, Illei GG, El-Gabalawy HS, Boumpas DT (2002) Gelatinase expression and activity in the synovium and skin of patients with erosive psoriatic arthritis. J Rheumatol 29:107\u2013117","journal-title":"J Rheumatol"},{"key":"2743_CR15","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1093\/rheumatology\/keh199","volume":"43","author":"VP Nell","year":"2004","unstructured":"Nell VP, Machold KP, Eberl G et al (2004) Benefit of very early referral and very early therapy with disease-modifying anti-rheumatic drugs in patients with early rheumatoid arthritis. Rheumatology (Oxford) 43:906\u2013914","journal-title":"Rheumatology (Oxford)"},{"issue":"12","key":"2743_CR16","doi-asserted-by":"crossref","first-page":"10627","DOI":"10.1007\/s11033-012-1952-x","volume":"39","author":"YH Lee","year":"2012","unstructured":"Lee YH, Bae SC, Choi SJ, Ji JD, Song GG (2012) Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis. Mol Biol Rep 39(12):10627\u201310635","journal-title":"Mol Biol Rep"},{"key":"2743_CR17","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1046\/j.1365-3083.1996.d01-65.x","volume":"43","author":"G Bouma","year":"1996","unstructured":"Bouma G, Crusius JB, Oudkerk Pool M et al (1996) Secretion of tumour necrosis factor alpha and lymphotoxin alpha in relation to polymorphisms in the TNF genes and HLA-DR alleles. Relevance for inflammatory bowel disease. Scand J Immunol 43:456\u2013463","journal-title":"Scand J Immunol"},{"key":"2743_CR18","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1046\/j.1365-2249.1998.00662.x","volume":"113","author":"E Louis","year":"1998","unstructured":"Louis E, Franchimont D, Piron A et al (1998) Tumour necrosis factor (TNF) gene polymorphism influences TNF-alpha production in lipopolysaccharide (LPS)-stimulated whole blood cell culture in healthy humans. Clin Exp Immunol 113:401\u2013406","journal-title":"Clin Exp Immunol"},{"key":"2743_CR19","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S1097-2765(02)00599-3","volume":"10","author":"F Martinon","year":"2002","unstructured":"Martinon F, Burns K, Tschopp J (2002) The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 10:417\u2013426","journal-title":"Mol Cell"},{"key":"2743_CR20","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1056\/NEJMoa061592","volume":"356","author":"Y Jin","year":"2007","unstructured":"Jin Y, Mailloux CM, Gowan K et al (2007) NALP1 in vitiligo-associated multiple autoimmune disease. N Engl J Med 356:1216\u20131225","journal-title":"N Engl J Med"},{"key":"2743_CR21","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.1038\/sj.jid.5700953","volume":"127","author":"Y Jin","year":"2007","unstructured":"Jin Y, Birlea SA, Fain PR, Spritz RA (2007) Genetic variations in NALP1 are associated with generalized vitiligo in a Romanian population. J Invest Dermatol 127:2558\u20132562","journal-title":"J Invest Dermatol"},{"key":"2743_CR22","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1038\/jid.2009.273","volume":"130","author":"Y Jin","year":"2010","unstructured":"Jin Y, Riccardi SL, Gowan K, Fain PR, Spritz RA (2010) Fine-mapping of vitiligo susceptibility loci on chromosomes 7 and 9 and interactions with NLRP1 (NALP1). J Invest Dermatol 130:774\u2013783","journal-title":"J Invest Dermatol"},{"key":"2743_CR23","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1038\/gene.2008.85","volume":"10","author":"NF Magitta","year":"2009","unstructured":"Magitta NF, Boe Wolff AS, Johansson S et al (2009) A coding polymorphism in NALP1 confers risk for autoimmune Addison\u2019s disease and type 1 diabetes. Genes Immun 10:120\u2013124","journal-title":"Genes Immun"},{"key":"2743_CR24","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1002\/art.33370","volume":"64","author":"J Sui","year":"2012","unstructured":"Sui J, Li H, Fang Y et al (2012) NLRP1 gene polymorphism influences gene transcription and is a risk factor for rheumatoid arthritis in han chinese. Arthritis Rheum 64:647\u2013654","journal-title":"Arthritis Rheum"},{"key":"2743_CR25","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/art.1780310302","volume":"31","author":"FC Arnett","year":"1988","unstructured":"Arnett FC, Edworthy SM, Bloch DA et al (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31:315\u2013324","journal-title":"Arthritis Rheum"},{"key":"2743_CR26","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/art.1780270401","volume":"27","author":"S Linden van der","year":"1984","unstructured":"van der Linden S, Valkenburg HA, Cats A (1984) Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum 27:361\u2013368","journal-title":"Arthritis Rheum"},{"key":"2743_CR27","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.3899\/jrheum.120007","volume":"39","author":"J Cheng","year":"2012","unstructured":"Cheng J, Zhang H, Zhuang C, Liu R (2012) Peptidylarginine deiminase type 4 and methyl-CpG binding domain 4 polymorphisms in Chinese patients with rheumatoid arthritis. J Rheumatol 39:1159\u20131165","journal-title":"J Rheumatol"},{"key":"2743_CR28","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.clinbiochem.2012.02.007","volume":"45","author":"SS Veidal","year":"2012","unstructured":"Veidal SS, Larsen DV, Chen X et al (2012) MMP mediated type V collagen degradation (C5\u00a0M) is elevated in ankylosing spondylitis. Clin Biochem 45:541\u2013546","journal-title":"Clin Biochem"},{"key":"2743_CR29","doi-asserted-by":"crossref","first-page":"7622","DOI":"10.1158\/0008-5472.CAN-04-1521","volume":"64","author":"C Yu","year":"2004","unstructured":"Yu C, Zhou Y, Miao X et al (2004) Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer. Cancer Res 64:7622\u20137628","journal-title":"Cancer Res"},{"key":"2743_CR30","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.jvs.2011.07.051","volume":"55","author":"C Saracini","year":"2012","unstructured":"Saracini C, Bolli P, Sticchi E et al (2012) Polymorphisms of genes involved in extracellular matrix remodeling and abdominal aortic aneurysm. J Vasc Surg 55:171\u2013179","journal-title":"J Vasc Surg"},{"key":"2743_CR31","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1093\/mutage\/geq015","volume":"25","author":"B Peng","year":"2010","unstructured":"Peng B, Cao L, Ma X et al (2010) Meta-analysis of association between matrix metalloproteinases 2, 7 and 9 promoter polymorphisms and cancer risk. Mutagenesis 25:371\u2013379","journal-title":"Mutagenesis"},{"key":"2743_CR32","doi-asserted-by":"crossref","first-page":"R1","DOI":"10.1186\/ar1849","volume":"8","author":"J Rodriguez-Lopez","year":"2006","unstructured":"Rodriguez-Lopez J, Perez-Pampin E, Gomez-Reino JJ, Gonzalez A (2006) Regulatory polymorphisms in extracellular matrix protease genes and susceptibility to rheumatoid arthritis: a case\u2013control study. Arthritis Res Ther 8:R1","journal-title":"Arthritis Res Ther"},{"key":"2743_CR33","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1744-313X.2007.00740.x","volume":"35","author":"L Jacq","year":"2008","unstructured":"Jacq L, Teixeira VH, Garnier S, Petit-Teixeira E, Cornelis F (2008) The MMP2 rs243865-T allele is not a major genetic factor for rheumatoid arthritis in the French Caucasian population. Int J Immunogenet 35:97\u201399","journal-title":"Int J Immunogenet"},{"key":"2743_CR34","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.cellimm.2011.06.023","volume":"271","author":"YM Hussein","year":"2011","unstructured":"Hussein YM, Mohamed RH, Pasha HF, El-Shahawy EE, Alzahrani SS (2011) Association of tumor necrosis factor alpha and its receptor polymorphisms with rheumatoid arthritis in female patients. Cell Immunol 271:192\u2013196","journal-title":"Cell Immunol"},{"key":"2743_CR35","first-page":"1788","volume":"28","author":"JH Yen","year":"2001","unstructured":"Yen JH, Chen CJ, Tsai WC et al (2001) Tumor necrosis factor promoter polymorphisms in patients with rheumatoid arthritis in Taiwan. J Rheumatol 28:1788\u20131792","journal-title":"J Rheumatol"},{"key":"2743_CR36","first-page":"212","volume":"29","author":"JT Cvetkovic","year":"2002","unstructured":"Cvetkovic JT, Wallberg-Jonsson S, Stegmayr B, Rantapaa-Dahlqvist S, Lefvert AK (2002) Susceptibility for and clinical manifestations of rheumatoid arthritis are associated with polymorphisms of the TNF-alpha, IL-1beta, and IL-1Ra genes. J Rheumatol 29:212\u2013219","journal-title":"J Rheumatol"},{"key":"2743_CR37","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1080\/03009740510026373","volume":"34","author":"A Pawlik","year":"2005","unstructured":"Pawlik A, Florczak M, Ostanek L et al (2005) TNF-alpha \u2212308 promoter polymorphism in patients with rheumatoid arthritis. Scand J Rheumatol 34:22\u201326","journal-title":"Scand J Rheumatol"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-013-2743-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11033-013-2743-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-013-2743-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T03:16:17Z","timestamp":1559358977000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11033-013-2743-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,25]]},"references-count":37,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["2743"],"URL":"https:\/\/doi.org\/10.1007\/s11033-013-2743-8","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,25]]}}}