{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T23:45:09Z","timestamp":1774050309077,"version":"3.50.1"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2015,12,24]],"date-time":"2015-12-24T00:00:00Z","timestamp":1450915200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100008091","name":"Golestan university of Medical Sciences","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100008091","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1007\/s11033-015-3939-x","type":"journal-article","created":{"date-parts":[[2015,12,24]],"date-time":"2015-12-24T05:50:02Z","timestamp":1450936202000},"page":"65-72","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Identification of new SOX2OT transcript variants highly expressed in human cancer cell lines and down regulated in stem cell differentiation"],"prefix":"10.1007","volume":"43","author":[{"given":"Marie","family":"Saghaeian Jazi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nader Mansour","family":"Samaei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mostafa","family":"Ghanei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Behgam","family":"Shadmehr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed Javad","family":"Mowla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,12,24]]},"reference":[{"issue":"7146","key":"3939_CR1","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1038\/nature05874","volume":"447","author":"E Birney","year":"2007","unstructured":"Birney E, Stamatoyannopoulos JA, Dutta A, Guig\u00f3 R, Gingeras TR, Margulies EH, Weng Z, Snyder M, Dermitzakis ET, Thurman RE (2007) Identification and analysis of functional elements in 1\u00a0% of the human genome by the ENCODE pilot project. Nature 447(7146):799\u2013816","journal-title":"Nature"},{"issue":"5740","key":"3939_CR2","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1126\/science.1112014","volume":"309","author":"P Carninci","year":"2005","unstructured":"Carninci P, Kasukawa T, Katayama S, Gough J, Frith M, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C (2005) The transcriptional landscape of the mammalian genome. Science 309(5740):1559\u20131563","journal-title":"Science"},{"issue":"5696","key":"3939_CR3","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1126\/science.1105136","volume":"306","author":"Consortium EP","year":"2004","unstructured":"Consortium EP (2004) The ENCODE (ENCyclopedia of DNA elements) project. Science 306(5696):636\u2013640","journal-title":"Science"},{"issue":"7011","key":"3939_CR4","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1038\/nature03001","volume":"431","author":"Consortium IHGS","year":"2004","unstructured":"Consortium IHGS (2004) Finishing the euchromatic sequence of the human genome. Nature 431(7011):931\u2013945","journal-title":"Nature"},{"issue":"7\u20138","key":"3939_CR5","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1007\/s00335-008-9136-7","volume":"19","author":"PP Amaral","year":"2008","unstructured":"Amaral PP, Mattick JS (2008) Noncoding RNA in development. Mamm Genome 19(7\u20138):454\u2013492","journal-title":"Mamm Genome"},{"issue":"5830","key":"3939_CR6","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1126\/science.1138341","volume":"316","author":"P Kapranov","year":"2007","unstructured":"Kapranov P, Cheng J, Dike S, Nix DA, Duttagupta R, Willingham AT, Stadler PF, Hertel J, Hackerm\u00fcller J, Hofacker IL (2007) RNA maps reveal new RNA classes and a possible function for pervasive transcription. Science 316(5830):1484\u20131488","journal-title":"Science"},{"issue":"4","key":"3939_CR7","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.cell.2009.02.006","volume":"136","author":"CP Ponting","year":"2009","unstructured":"Ponting CP, Oliver PL, Reik W (2009) Evolution and functions of long noncoding RNAs. Cell 136(4):629\u2013641","journal-title":"Cell"},{"issue":"3","key":"3939_CR8","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.ceb.2010.03.003","volume":"22","author":"L-L Chen","year":"2010","unstructured":"Chen L-L, Carmichael GG (2010) Decoding the function of nuclear long non-coding RNAs. Curr Opin Cell Biol 22(3):357\u2013364","journal-title":"Curr Opin Cell Biol"},{"issue":"3","key":"3939_CR9","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1093\/cvr\/cvr097","volume":"90","author":"MU Kaikkonen","year":"2011","unstructured":"Kaikkonen MU, Lam MT, Glass CK (2011) Non-coding RNAs as regulators of gene expression and epigenetics. Cardiovasc Res 90(3):430\u2013440","journal-title":"Cardiovasc Res"},{"issue":"2","key":"3939_CR10","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1002\/path.2638","volume":"220","author":"RJ Taft","year":"2010","unstructured":"Taft RJ, Pang KC, Mercer TR, Dinger M, Mattick JS (2010) Non-coding RNAs: regulators of disease. J Pathol 220(2):126\u2013139","journal-title":"J Pathol"},{"issue":"1","key":"3939_CR11","doi-asserted-by":"crossref","first-page":"a003756","DOI":"10.1101\/cshperspect.a003756","volume":"3","author":"X Wang","year":"2011","unstructured":"Wang X, Song X, Glass CK, Rosenfeld MG (2011) The long arm of long noncoding RNAs: roles as sensors regulating gene transcriptional programs. Cold Spring Harb Perspect Biol 3(1):a003756","journal-title":"Cold Spring Harb Perspect Biol"},{"issue":"13","key":"3939_CR12","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1101\/gad.1800909","volume":"23","author":"JE Wilusz","year":"2009","unstructured":"Wilusz JE, Sunwoo H, Spector DL (2009) Long noncoding RNAs: functional surprises from the RNA world. Genes Dev 23(13):1494\u20131504","journal-title":"Genes Dev"},{"issue":"7232","key":"3939_CR13","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1038\/nature07759","volume":"457","author":"K Fejes-Toth","year":"2009","unstructured":"Fejes-Toth K, Sotirova V, Sachidanandam R, Assaf G, Hannon GJ, Kapranov P, Foissac S, Willingham AT, Duttagupta R, Dumais E (2009) Post-transcriptional processing generates a diversity of 5\u2032-modified long and short RNAs. Nature 457(7232):1028\u20131032","journal-title":"Nature"},{"issue":"4","key":"3939_CR14","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/ng1120","volume":"33","author":"J Fantes","year":"2003","unstructured":"Fantes J, Ragge NK, Lynch S-A, McGill NI, Collin JRO, Howard-Peebles PN, Hayward C, Vivian AJ, Williamson K, van Heyningen V (2003) Mutations in SOX2 cause anophthalmia. Nat Genet 33(4):461\u2013463","journal-title":"Nat Genet"},{"issue":"10","key":"3939_CR15","doi-asserted-by":"crossref","first-page":"e1000220","DOI":"10.1371\/journal.pgen.1000220","volume":"4","author":"T Andrew","year":"2008","unstructured":"Andrew T, Maniatis N, Carbonaro F, Liew SM, Lau W, Spector TD, Hammond CJ (2008) Identification and replication of three novel myopia common susceptibility gene loci on chromosome 3q26 using linkage and linkage disequilibrium mapping. PLoS Genet 4(10):e1000220","journal-title":"PLoS Genet"},{"issue":"1","key":"3939_CR16","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1002\/stem.1542","volume":"32","author":"A Shahryari","year":"2014","unstructured":"Shahryari A, Rafiee MR, Fouani Y, Oliae NA, Samaei NM, Shafiee M, Semnani S, Vasei M, Mowla SJ (2014) Two novel splice variants of SOX2OT, SOX2OT\u2010S1, and SOX2OT\u2010S2 are coupregulated with SOX2 and OCT4 in esophageal squamous cell carcinoma. Stem Cells 32(1):126\u2013134","journal-title":"Stem Cells"},{"issue":"11","key":"3939_CR17","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1261\/rna.1705309","volume":"15","author":"PP Amaral","year":"2009","unstructured":"Amaral PP, Neyt C, Wilkins SJ, Askarian-Amiri ME, Sunkin SM, Perkins AC, Mattick JS (2009) Complex architecture and regulated expression of the Sox2ot locus during vertebrate development. RNA 15(11):2013\u20132027","journal-title":"RNA"},{"issue":"1","key":"3939_CR18","doi-asserted-by":"crossref","first-page":"e8960","DOI":"10.1371\/journal.pone.0008960","volume":"5","author":"T Hussenet","year":"2010","unstructured":"Hussenet T, Dali S, Exinger J, Monga B, Jost B, Dembel\u00e9 D, Martinet N, Thibault C, Huelsken J, Brambilla E (2010) SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas. PLoS One 5(1):e8960","journal-title":"PLoS One"},{"issue":"7","key":"3939_CR19","doi-asserted-by":"crossref","first-page":"e102140","DOI":"10.1371\/journal.pone.0102140","volume":"9","author":"ME Askarian-Amiri","year":"2014","unstructured":"Askarian-Amiri ME, Seyfoddin V, Smart CE, Wang J, Kim JE, Hansji H, Baguley BC, Finlay GJ, Leung EY (2014) Emerging role of long non-coding RNA SOX2OT in SOX2 regulation in breast cancer. PLoS One 9(7):e102140","journal-title":"PLoS One"},{"key":"3939_CR20","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.biocel.2014.06.004","volume":"53","author":"Z Hou","year":"2014","unstructured":"Hou Z, Zhao W, Zhou J, Shen L, Zhan P, Xu C, Chang C, Bi H, Zou J, Yao X (2014) A long noncoding RNA Sox2ot regulates lung cancer cell proliferation and is a prognostic indicator of poor survival. Int J Biochem Cell Biol\u00a053:380\u2013388","journal-title":"Int J Biochem Cell Biol"},{"issue":"12","key":"3939_CR21","doi-asserted-by":"crossref","first-page":"3068","DOI":"10.1634\/stemcells.2008-0530","volume":"26","author":"Y Atlasi","year":"2008","unstructured":"Atlasi Y, Mowla SJ, Ziaee SA, Gokhale PJ, Andrews PW (2008) OCT4 spliced variants are differentially expressed in human pluripotent and nonpluripotent cells. Stem Cells 26(12):3068\u20133074","journal-title":"Stem Cells"},{"issue":"suppl 1","key":"3939_CR22","doi-asserted-by":"crossref","first-page":"R17","DOI":"10.1093\/hmg\/ddl046","volume":"15","author":"JS Mattick","year":"2006","unstructured":"Mattick JS, Makunin IV (2006) Non-coding RNA. Hum Mol Genet 15(suppl 1):R17\u2013R29","journal-title":"Hum Mol Genet"},{"issue":"2","key":"3939_CR23","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1073\/pnas.0706729105","volume":"105","author":"TR Mercer","year":"2008","unstructured":"Mercer TR, Dinger ME, Sunkin SM, Mehler MF, Mattick JS (2008) Specific expression of long noncoding RNAs in the mouse brain. Proc Natl Acad Sci 105(2):716\u2013721","journal-title":"Proc Natl Acad Sci"},{"key":"3939_CR24","doi-asserted-by":"crossref","first-page":"196","DOI":"10.3389\/fgene.2015.00196","volume":"6","author":"A Shahryari","year":"2015","unstructured":"Shahryari A, Jazi MS, Samaei NM, Mowla SJ (2015) Long non-coding RNA SOX2OT: expression signature, splicing patterns, and emerging roles in pluripotency and tumorigenesis. Front Genet 6:196","journal-title":"Front Genet"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-015-3939-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11033-015-3939-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-015-3939-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,16]],"date-time":"2020-05-16T07:33:08Z","timestamp":1589614388000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11033-015-3939-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,24]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["3939"],"URL":"https:\/\/doi.org\/10.1007\/s11033-015-3939-x","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,24]]}}}