{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T02:49:18Z","timestamp":1761101358949,"version":"3.37.3"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100005317","name":"Kermanshah University of Medical Sciences","doi-asserted-by":"publisher","award":["90324"],"award-info":[{"award-number":["90324"]}],"id":[{"id":"10.13039\/501100005317","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.1007\/s11033-018-4530-z","type":"journal-article","created":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T15:47:32Z","timestamp":1543679252000},"page":"741-749","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Association between activity and genotypes of paraoxonase1 L55M (rs854560) increases the disease activity of rheumatoid arthritis through oxidative stress"],"prefix":"10.1007","volume":"46","author":[{"given":"Maryam","family":"Tanhapour","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiva","family":"Shahmohamadnejad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3042-2832","authenticated-orcid":false,"given":"Asad","family":"Vaisi-Raygani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Kiani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yadola","family":"Shakiba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zohreh","family":"Rahimi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fariborz","family":"Bahrehmand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ebrahim","family":"Shakiba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali-Akbar","family":"Vaisi-Raygani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Alibakhshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atefeh","family":"Eivazi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tayebeh","family":"Pourmotabbed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,12,1]]},"reference":[{"key":"4530_CR1","doi-asserted-by":"publisher","first-page":"384","DOI":"10.3389\/fimmu.2015.00384","volume":"6","author":"M Mellado","year":"2015","unstructured":"Mellado M, Martinez-Munoz L, Cascio G, Lucas P, Pablos JL, Rodriguez-Frade JM (2015) T cell migration in rheumatoid arthritis. Front Immunol 6:384","journal-title":"Front Immunol"},{"issue":"4","key":"4530_CR2","doi-asserted-by":"publisher","first-page":"e0152925","DOI":"10.1371\/journal.pone.0152925","volume":"11","author":"S Mateen","year":"2016","unstructured":"Mateen S, Moin S, Khan AQ, Zafar A, Fatima N (2016) Increased reactive oxygen species formation and oxidative stress in rheumatoid arthritis. PLoS ONE 11(4):e0152925","journal-title":"PLoS ONE"},{"issue":"3","key":"4530_CR3","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.semarthrit.2006.08.006","volume":"36","author":"Y Alamanos","year":"2006","unstructured":"Alamanos Y, Voulgari PV, Drosos AA (2006) Incidence and prevalence of rheumatoid arthritis, based on the 1987 American College of Rheumatology criteria: a systematic review. Semin Arthritis Rheum 36(3):182\u2013188","journal-title":"Semin Arthritis Rheum"},{"issue":"3","key":"4530_CR4","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1016\/S0889-857X(05)70154-X","volume":"26","author":"SA Y.Yazici","year":"2000","unstructured":"Y.Yazici SA, Paget (2000) Elderly-onset rheumatoid arthritis. Rheum Dis Clin N Am 26(3):517\u2013526","journal-title":"Rheum Dis Clin N Am"},{"issue":"2","key":"4530_CR5","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1037\/0033-2909.98.2.358","volume":"98","author":"KO Anderson","year":"1985","unstructured":"Anderson KO, Bradley LA, Young LD, McDaniel LK, Wise CM (1985) Rheumatoid arthritis: review of psychological factors related to etiology, effects, and treatment. Psychol bull 98(2):358","journal-title":"Psychol bull"},{"issue":"2","key":"4530_CR6","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/S0167-5699(99)01552-2","volume":"21","author":"PP Tak","year":"2000","unstructured":"Tak PP, Zvaifler NJ, Green DR, Firestein GS (2000) Rheumatoid arthritis and p53: how oxidative stress might alter the course of inflammatory diseases. Immunol Today 21(2):78\u201382","journal-title":"Immunol Today"},{"issue":"8","key":"4530_CR7","doi-asserted-by":"publisher","first-page":"5421","DOI":"10.1007\/s11033-011-0696-3","volume":"38","author":"A Vaisi-Raygani","year":"2011","unstructured":"Vaisi-Raygani A, Ghaneialvar H, Rahimi Z, Tavilani H, Pourmotabbed T, Shakiba E, Vaisi-Raygani A, Kiani A, Aminian M, Alibakhshi R, Bartels C (2011) Paraoxonase Arg 192 allele is an independent risk factor for three-vessel stenosis of coronary artery disease. Mol Biol Rep 38(8):5421\u20135428 C.","journal-title":"Mol Biol Rep"},{"issue":"11","key":"4530_CR8","doi-asserted-by":"publisher","first-page":"2765","DOI":"10.1002\/art.38118","volume":"65","author":"C Charles-Schoeman","year":"2013","unstructured":"Charles-Schoeman C, Lee YY, Shahbazian A, Gorn AH, Fitzgerald J, Ranganath VK, Taylor M, Ragavendra N, McMahon M, Elashoff D, Reddy ST (2013) Association of paraoxonase 1 gene polymorphism and enzyme activity with carotid plaque in rheumatoid arthritis. Arthritis Rheum 65(11): 2765\u20132772","journal-title":"Arthritis Rheum"},{"issue":"3","key":"4530_CR9","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1007\/s10067-017-3896-y","volume":"37","author":"C Charles-Schoeman","year":"2018","unstructured":"Charles-Schoeman C, Meriwether D, Lee YY, Shahbazian A, Reddy ST (2018) High levels of oxidized fatty acids in HDL are associated with impaired HDL function in patients with active rheumatoid arthritis. Clin Rheumatol 37(3):615\u2013622","journal-title":"Clin Rheumatol"},{"issue":"3","key":"4530_CR10","first-page":"211","volume":"12","author":"F Bahrehmand","year":"2013","unstructured":"Bahrehmand F, Vaisi-Raygani A, Ahmadi R, Kiani A, Rahimi Z, Tavilani H et al (2013) Paraoxonase (PON1) 55 polymorphism and association with systemic lupus erythematosus. Iran J Allergy Asthma Immunol 12(3):211\u2013219","journal-title":"Iran J Allergy Asthma Immunol"},{"key":"4530_CR11","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.clinbiochem.2014.08.016","volume":"48","author":"S Shahmohamadnejad","year":"2015","unstructured":"Shahmohamadnejad S, Vaisi-Raygani A, Shakiba Y, Kiani A, Rahimi Z, Bahrehmand F et al (2015) Association between butyrylcholinesterase activity and phenotypes, paraoxonase192 rs662 gene polymorphism and their enzymatic activity with severity of rheumatoid arthritis: correlation with systemic inflammatory markers and oxidative stress, preliminary report. Clin Biochem 48:63\u201369","journal-title":"Clin Biochem"},{"issue":"3","key":"4530_CR12","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1177\/0961203313518622","volume":"23","author":"F Bahrehmand","year":"2014","unstructured":"Bahrehmand F, Vaisi-Raygani A, Rahimi Z, Ahmadi R, Kiani A, Tavilani H et al (2014) Synergistic effects of BuChE non-UU phenotype and paraoxonase (PON1) 55 M allele on the risk of systemic lupus erythematosus: influence on lipid and lipoprotein metabolism and oxidative stress, preliminary report. Lupus 23(3):263\u2013272","journal-title":"Lupus"},{"issue":"3","key":"4530_CR13","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1016\/j.clinbiochem.2008.10.025","volume":"42","author":"A Vaisi-Raygani","year":"2009","unstructured":"Vaisi-Raygani A, Tavilani H, Zahrai M, Rahimi Z, Sheikh N, Aminian M et al (2009) Serum butyrylcholinesterase activity and phenotype associations with lipid profile in stroke patients. Clin Biochem 42(3):210\u2013214","journal-title":"Clin Biochem"},{"issue":"16","key":"4530_CR14","doi-asserted-by":"publisher","first-page":"1590","DOI":"10.3109\/14767058.2013.795534","volume":"26","author":"Z Rahimi","year":"2013","unstructured":"Rahimi Z, Ahmadi R, Vaisi-Raygani A, Rahimi Z, Bahrehmand F, Parsian A (2013) Butyrylcholinesterase (BChE) activity is associated with the risk of preeclampsia: influence on lipid and lipoprotein metabolism and oxidative stress. J Matern Fetal Neonatal Med 26(16):1590\u20131594","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"6","key":"4530_CR15","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1111\/j.1365-2133.2012.11170.x","volume":"167","author":"M Asefi","year":"2012","unstructured":"Asefi M, Vaisi-Raygani A, Bahrehmand F, Kiani A, Rahimi Z, Nomani H et al (2012) Paraoxonase 1 (PON1) 55 polymorphism, lipid profiles and psoriasis. Br J Dermatol 167(6):1279\u20131286","journal-title":"Br J Dermatol"},{"issue":"7","key":"4530_CR16","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1038\/nrrheum.2011.76","volume":"7","author":"WJ Venrooij van","year":"2011","unstructured":"van Venrooij WJ, van Beers JJ, Pruijn GJ (2011) Anti-CCP antibodies: the past, the present and the future. Nat Rev Rheumatol 7(7):391\u2013398","journal-title":"Nat Rev Rheumatol"},{"issue":"3","key":"4530_CR17","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/j.intimp.2013.08.022","volume":"17","author":"D Arshadi","year":"2013","unstructured":"Arshadi D, Nikbin B, Shakiba Y, Kiani A, Jamshidi AR, Boroushaki MT (2013) Plasma level of neopterin as a marker of disease activity in treated rheumatoid arthritis patients: association with gender, disease activity andd anti-CCP antibod. Int Immunopharmacol 17(3):763\u2013767","journal-title":"Int Immunopharmacol"},{"issue":"7","key":"4530_CR18","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.1136\/annrheumdis-2013-204933","volume":"73","author":"MA Gonz\u00e1lez-Gay","year":"2014","unstructured":"Gonz\u00e1lez-Gay MA, Gonz\u00e1lez-Juanatey C (2014) Inflammation and lipid profile in rheumatoid arthritis: bridging an apparent paradox. Ann Rheum Dis 73(7):1281\u20131283","journal-title":"Ann Rheum Dis"},{"issue":"6","key":"4530_CR19","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1038\/ajh.2009.54","volume":"22","author":"FM Versen-Hoeynck von","year":"2009","unstructured":"von Versen-Hoeynck FM, Hubel CA, Gallaher MJ, Gammill HS, Powers RW (2009) Plasma levels of inflammatory markers neopterin, sialic acid, and C-reactive protein in pregnancy and preeclampsia. Am J hypertens 22(6):687\u2013692","journal-title":"Am J hypertens"},{"issue":"3","key":"4530_CR20","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1002\/art.1780310302","volume":"31","author":"FC Arnett","year":"1988","unstructured":"Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS et al (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31(3):315\u2013324","journal-title":"Arthritis Rheum"},{"issue":"1","key":"4530_CR21","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1038\/ng0193-73","volume":"3","author":"R Humbert","year":"1993","unstructured":"Humbert R, Adler DA, Disteche CM, Hassett C, Omiecinski CJ, Furlong CE (1993) The molecular basis of the human serum paraoxonase activity polymorphism. Nat Genet 3(1):73\u201376","journal-title":"Nat Genet"},{"issue":"2","key":"4530_CR22","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1080\/00365510701576180","volume":"68","author":"A Vaisi-Raygani","year":"2008","unstructured":"Vaisi-Raygani A, Rahimi Z, Entezami H, Kharrazi H, Bahrhemand F, Tavilani H et al (2008) Butyrylcholinesterase K variants increase the risk of coronary artery disease in the population of western Iran, Scand. J Clin Lab Invest 68(2):123\u2013129","journal-title":"J Clin Lab Invest"},{"issue":"10","key":"4530_CR23","doi-asserted-by":"publisher","first-page":"1555","DOI":"10.1089\/dna.2012.1631","volume":"31","author":"M Teranishi","year":"2012","unstructured":"Teranishi M, Uchida Y, Nishio N, Kato K, Otake H, Yoshida T et al (2012) Polymorphisms in genes involved in oxidative stress response in patients with sudden sensorineural hearing loss and Meniere\u2019s disease in a Japanese population. DNA Cell Biol 31(10):1555\u20131562","journal-title":"DNA Cell Biol"},{"issue":"5 Suppl 31","key":"4530_CR24","first-page":"S71","volume":"21","author":"T Sokka","year":"2003","unstructured":"Sokka T (2003) Work disability in early rheumatoid arthritis. Clin Exp Rheumatol 21(5 Suppl 31):S71\u2013S74","journal-title":"Clin Exp Rheumatol"},{"issue":"9","key":"4530_CR25","doi-asserted-by":"publisher","first-page":"1481","DOI":"10.1007\/s00296-017-3771-9","volume":"37","author":"H Hirvonen","year":"2017","unstructured":"Hirvonen H, Kautiainen H, Moilanen E, Mikkelsson M, Leirisalo-Repo M (2017) The effect of cryotherapy on total antioxidative capacity in patients with active seropositive rheumatoid arthritis. Rheumatol Int 37(9):1481\u20131487","journal-title":"Rheumatol Int"},{"issue":"12","key":"4530_CR26","first-page":"56","volume":"62","author":"M Tanhapour","year":"2016","unstructured":"Tanhapour M, Vaisi-Raygani A, Bahrehmand F, Khazaei M, Kiani A, Rahimi Z et al (2016) Association between the cytotoxic T-lymphocyte antigen-4 mutations and the susceptibility to systemic lupus erythematosus; contribution markers of inflammation and oxidative stress. Cell Mol Biol 62(12):56\u201361","journal-title":"Cell Mol Biol"},{"issue":"4","key":"4530_CR27","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1007\/s10067-017-3859-3","volume":"37","author":"M Tanhapour","year":"2017","unstructured":"Tanhapour M, Miri A, Vaisi-Raygani A, Bahrehmand F, Kiani A, Rahimi Z et al (2017) Synergism between apolipoprotein E \u01904 allele and paraoxonase (PON1) 55-M allele is associated with risk of systemic lupus erythematosus. Clin Rheumatol 37(4):971\u2013977","journal-title":"Clin Rheumatol"},{"issue":"7","key":"4530_CR28","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1007\/s00059-017-4611-0","volume":"43","author":"H Chen","year":"2017","unstructured":"Chen H, Ding S, Zhou M, Wu X, Liu X, Liu J et al (2017) PON1 L55M and Q192R gene polymorphisms and CAD risks in patients with hyperlipidemia: clinical study of possible associations, Herz 43(7):642\u2013648","journal-title":"Herz"},{"issue":"3","key":"4530_CR29","doi-asserted-by":"publisher","first-page":"1735","DOI":"10.4238\/vol9-3gmr893","volume":"9","author":"M Hashemi","year":"2010","unstructured":"Hashemi M, Moazeni-Roodi AK, Fazaeli A, Sandoughi M, Taheri M, Bardestani GR et al (2010) The L55M polymorphism of paraoxonase-1 is a risk factor for rheumatoid arthritis. Genet Mol Res 9(3):1735\u20131741","journal-title":"Genet Mol Res"},{"issue":"6","key":"4530_CR30","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1530\/EJE-15-0617","volume":"173","author":"I Ates","year":"2015","unstructured":"Ates I, Yilmaz FM, Altay M, Yilmaz N, Berker D, Guler S (2015) The relationship between oxidative stress and autoimmunity in Hashimoto\u2019s thyroiditis. Eur J Endocrinol 173(6):791\u2013799","journal-title":"Eur J Endocrinol"},{"key":"4530_CR31","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.jaut.2015.06.004","volume":"62","author":"FM Strickland","year":"2015","unstructured":"Strickland FM, Li Y, Johnson K, Sun Z, Richardson BC (2015) CD4 (+) T cells epigenetically modified by oxidative stress cause lupus-like autoimmunity in mice. J Autoimmun 62:75\u201380","journal-title":"J Autoimmun"},{"key":"4530_CR32","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1186\/1423-0127-21-23","volume":"21","author":"D Shah","year":"2014","unstructured":"Shah D, Mahajan N, Sah S, Nath SK, Paudyal B (2014) Oxidative stress and its biomarkers in systemic lupus erythematosus. J Biomed Sci 21:23","journal-title":"J Biomed Sci"},{"issue":"3","key":"4530_CR33","doi-asserted-by":"publisher","first-page":"184","DOI":"10.3109\/03009742.2013.836564","volume":"43","author":"A Lo Gullo","year":"2014","unstructured":"Lo Gullo A, Mandraffino G, Sardo MA, D\u2019Ascola A, Mamone F, Loddo S et al (2014) Circulating progenitor cells in rheumatoid arthritis: association with inflammation and oxidative stress. Scand J Rheumatol 43(3):184\u2013193","journal-title":"Scand J Rheumatol"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-018-4530-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11033-018-4530-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-018-4530-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T07:46:30Z","timestamp":1575272790000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11033-018-4530-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,1]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["4530"],"URL":"https:\/\/doi.org\/10.1007\/s11033-018-4530-z","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"type":"print","value":"0301-4851"},{"type":"electronic","value":"1573-4978"}],"subject":[],"published":{"date-parts":[[2018,12,1]]},"assertion":[{"value":"3 October 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 November 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 December 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}