{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:43:08Z","timestamp":1786981388810,"version":"build-2736575974"},"reference-count":121,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T00:00:00Z","timestamp":1580947200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T00:00:00Z","timestamp":1580947200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1007\/s11033-020-05298-6","type":"journal-article","created":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T01:02:46Z","timestamp":1580950966000},"page":"2381-2389","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["An update on human periapical cyst-mesenchymal stem cells and their potential applications in regenerative medicine"],"prefix":"10.1007","volume":"47","author":[{"given":"Sara","family":"Ayoub","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7283-3456","authenticated-orcid":false,"given":"Antoine","family":"Berb\u00e9ri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8442-1619","authenticated-orcid":false,"given":"Mohammad","family":"Fayyad-kazan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,2,6]]},"reference":[{"issue":"11","key":"5298_CR1","doi-asserted-by":"publisher","first-page":"2896","DOI":"10.1634\/stemcells.2007-0637","volume":"25","author":"DG Phinney","year":"2007","unstructured":"Phinney DG, Prockop DJ (2007) Concise review: mesenchymal stem\/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair\u2014current views. Stem Cells 25(11):2896\u20132902","journal-title":"Stem Cells"},{"issue":"11","key":"5298_CR2","doi-asserted-by":"publisher","first-page":"1604","DOI":"10.1016\/j.exphem.2006.07.014","volume":"34","author":"DP Lennon","year":"2006","unstructured":"Lennon DP, Caplan AI (2006) Isolation of human marrow-derived mesenchymal stem cells. Exp Hematol 34(11):1604\u20131605","journal-title":"Exp Hematol"},{"issue":"3","key":"5298_CR3","doi-asserted-by":"publisher","first-page":"195","DOI":"10.14712\/18059694.2017.82","volume":"50","author":"J Suchanek","year":"2007","unstructured":"Suchanek J et al (2007) Human dental pulp stem cells\u2013isolation and long term cultivation. Acta Medica (Hradec Kralove) 50(3):195\u2013201","journal-title":"Acta Medica (Hradec Kralove)"},{"issue":"4","key":"5298_CR4","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1634\/stemcells.22-4-625","volume":"22","author":"K Bieback","year":"2004","unstructured":"Bieback K et al (2004) Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood. Stem Cells 22(4):625\u2013634","journal-title":"Stem Cells"},{"issue":"12","key":"5298_CR5","doi-asserted-by":"publisher","first-page":"4279","DOI":"10.1091\/mbc.e02-02-0105","volume":"13","author":"PA Zuk","year":"2002","unstructured":"Zuk PA et al (2002) Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 13(12):4279\u20134295","journal-title":"Mol Biol Cell"},{"issue":"25","key":"5298_CR6","doi-asserted-by":"publisher","first-page":"13625","DOI":"10.1073\/pnas.240309797","volume":"97","author":"S Gronthos","year":"2000","unstructured":"Gronthos S et al (2000) Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proc Natl Acad Sci USA 97(25):13625\u201313630","journal-title":"Proc Natl Acad Sci USA"},{"issue":"11","key":"5298_CR7","doi-asserted-by":"publisher","first-page":"2739","DOI":"10.1634\/stemcells.2007-0197","volume":"25","author":"G Chamberlain","year":"2007","unstructured":"Chamberlain G et al (2007) Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing. Stem Cells 25(11):2739\u20132749","journal-title":"Stem Cells"},{"issue":"4","key":"5298_CR8","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1080\/14653240600855905","volume":"8","author":"M Dominici","year":"2006","unstructured":"Dominici M et al (2006) Minimal criteria for defining multipotent mesenchymal stromal cells: the international society for cellular therapy position statement. Cytotherapy 8(4):315\u2013317","journal-title":"Cytotherapy"},{"key":"5298_CR9","doi-asserted-by":"publisher","first-page":"6940283","DOI":"10.1155\/2016\/6940283","volume":"2016","author":"RS Mahla","year":"2016","unstructured":"Mahla RS (2016) Stem cells applications in regenerative medicine and disease therapeutics. Int J Cell Biol 2016:6940283","journal-title":"Int J Cell Biol"},{"issue":"3","key":"5298_CR10","doi-asserted-by":"publisher","first-page":"226","DOI":"10.7150\/ijbs.5.226","volume":"5","author":"DS Koussoulakou","year":"2009","unstructured":"Koussoulakou DS, Margaritis LH, Koussoulakos SL (2009) A curriculum vitae of teeth: evolution, generation, regeneration. Int J Biol Sci 5(3):226\u2013243","journal-title":"Int J Biol Sci"},{"issue":"3","key":"5298_CR11","doi-asserted-by":"publisher","first-page":"373","DOI":"10.5507\/bp.2013.078","volume":"158","author":"P Stanko","year":"2014","unstructured":"Stanko P et al (2014) Comparison of human mesenchymal stem cells derived from dental pulp, bone marrow, adipose tissue, and umbilical cord tissue by gene expression. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 158(3):373\u2013377","journal-title":"Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub"},{"key":"5298_CR12","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1038\/sj.bdj.2018.348","volume":"224","author":"P Hollands","year":"2018","unstructured":"Hollands P, Aboyeji D, Orcharton M (2018) Dental pulp stem cells in regenerative medicine. Br Dent J 224:747\u2013750","journal-title":"Br Dent J"},{"issue":"10","key":"5298_CR13","doi-asserted-by":"publisher","first-page":"5807","DOI":"10.1073\/pnas.0937635100","volume":"100","author":"M Miura","year":"2003","unstructured":"Miura M et al (2003) SHED: stem cells from human exfoliated deciduous teeth. Proc Natl Acad Sci USA 100(10):5807\u20135812","journal-title":"Proc Natl Acad Sci USA"},{"issue":"3\u20134","key":"5298_CR14","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1159\/000099617","volume":"184","author":"I Kerkis","year":"2006","unstructured":"Kerkis I et al (2006) Isolation and characterization of a population of immature dental pulp stem cells expressing OCT-4 and other embryonic stem cell markers. Cells Tissues Organs 184(3\u20134):105\u2013116","journal-title":"Cells Tissues Organs"},{"issue":"9429","key":"5298_CR15","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/S0140-6736(04)16627-0","volume":"364","author":"BM Seo","year":"2004","unstructured":"Seo BM et al (2004) Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet 364(9429):149\u2013155","journal-title":"Lancet"},{"issue":"2","key":"5298_CR16","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.matbio.2004.12.004","volume":"24","author":"C Morsczeck","year":"2005","unstructured":"Morsczeck C et al (2005) Isolation of precursor cells (PCs) from human dental follicle of wisdom teeth. Matrix Biol 24(2):155\u2013165","journal-title":"Matrix Biol"},{"issue":"2","key":"5298_CR17","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.joen.2007.11.021","volume":"34","author":"W Sonoyama","year":"2008","unstructured":"Sonoyama W et al (2008) Characterization of the apical papilla and its residing stem cells from human immature permanent teeth: a pilot study. J Endod 34(2):166\u2013171","journal-title":"J Endod"},{"issue":"10","key":"5298_CR18","doi-asserted-by":"publisher","first-page":"1070","DOI":"10.7150\/ijbs.6662","volume":"9","author":"M Marrelli","year":"2013","unstructured":"Marrelli M, Paduano F, Tatullo M (2013) Cells isolated from human periapical cysts express mesenchymal stem cell-like properties. Int J Biol Sci 9(10):1070\u20131078","journal-title":"Int J Biol Sci"},{"issue":"11","key":"5298_CR19","doi-asserted-by":"publisher","first-page":"2493","DOI":"10.1634\/stemcells.2006-0161","volume":"24","author":"K Iohara","year":"2006","unstructured":"Iohara K et al (2006) Side population cells isolated from porcine dental pulp tissue with self-renewal and multipotency for dentinogenesis, chondrogenesis, adipogenesis, and neurogenesis. Stem Cells 24(11):2493\u20132503","journal-title":"Stem Cells"},{"issue":"3","key":"5298_CR20","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/j.joen.2009.12.022","volume":"36","author":"N Ishkitiev","year":"2010","unstructured":"Ishkitiev N et al (2010) Deciduous and permanent dental pulp mesenchymal cells acquire hepatic morphologic and functional features in vitro. J Endod 36(3):469\u2013474","journal-title":"J Endod"},{"issue":"9\u201310","key":"5298_CR21","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1111\/j.1432-0436.2004.07209010.x","volume":"72","author":"AJ Reynolds","year":"2004","unstructured":"Reynolds AJ, Jahoda CA (2004) Cultured human and rat tooth papilla cells induce hair follicle regeneration and fiber growth. Differentiation 72(9\u201310):566\u2013575","journal-title":"Differentiation"},{"issue":"10","key":"5298_CR22","doi-asserted-by":"publisher","first-page":"e13547","DOI":"10.1371\/journal.pone.0013547","volume":"5","author":"R Yang","year":"2010","unstructured":"Yang R et al (2010) Clones of ectopic stem cells in the regeneration of muscle defects in vivo. PLoS ONE 5(10):e13547","journal-title":"PLoS ONE"},{"key":"5298_CR23","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.archoralbio.2016.10.003","volume":"73","author":"RL Lima","year":"2017","unstructured":"Lima RL et al (2017) Human dental follicle cells express embryonic, mesenchymal and neural stem cells markers. Arch Oral Biol 73:121\u2013128","journal-title":"Arch Oral Biol"},{"issue":"1","key":"5298_CR24","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1186\/s13287-018-1077-9","volume":"9","author":"Y Tanaka","year":"2018","unstructured":"Tanaka Y et al (2018) Suppression of AKT-mTOR signal pathway enhances osteogenic\/dentinogenic capacity of stem cells from apical papilla. Stem Cell Res Ther 9(1):334","journal-title":"Stem Cell Res Ther"},{"key":"5298_CR25","doi-asserted-by":"publisher","first-page":"e79","DOI":"10.1371\/journal.pone.0000079","volume":"1","author":"W Sonoyama","year":"2006","unstructured":"Sonoyama W et al (2006) Mesenchymal stem cell-mediated functional tooth regeneration in swine. PLoS ONE 1:e79","journal-title":"PLoS ONE"},{"issue":"6","key":"5298_CR26","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1186\/scrt515","volume":"5","author":"Y Li","year":"2014","unstructured":"Li Y et al (2014) 17beta-estradiol promotes the odonto\/osteogenic differentiation of stem cells from apical papilla via mitogen-activated protein kinase pathway. Stem Cell Res Ther 5(6):125","journal-title":"Stem Cell Res Ther"},{"key":"5298_CR27","volume-title":"Oxford","author":"J Siqueira","year":"2008","unstructured":"Siqueira J, Moap J, Essential endodontology. (2008) Oxford. Blackwell, UK"},{"issue":"9","key":"5298_CR28","first-page":"598","volume":"69","author":"E Peters","year":"2003","unstructured":"Peters E, Lau M (2003) Histopathologic examination to confirm diagnosis of periapical lesions: a review. J Can Dent Assoc 69(9):598\u2013600","journal-title":"J Can Dent Assoc"},{"issue":"4","key":"5298_CR29","first-page":"193","volume":"12","author":"P Babal","year":"1989","unstructured":"Babal P et al (1989) Cellular composition of periapical granulomas and its function: histological, immunohistochemical and electronmicroscopic study. Czech Med 12(4):193\u2013215","journal-title":"Czech Med"},{"issue":"5","key":"5298_CR30","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1590\/1678-7757-2016-0464","volume":"25","author":"R Holland","year":"2017","unstructured":"Holland R et al (2017) Factors affecting the periapical healing process of endodontically treated teeth. J Appl Oral Sci 25(5):465\u2013476","journal-title":"J Appl Oral Sci"},{"issue":"4","key":"5298_CR31","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.trsl.2009.08.010","volume":"155","author":"J Patel","year":"2010","unstructured":"Patel J et al (2010) Foreign body-induced granulation tissue is a source of adult stem cells. Transl Res 155(4):191\u2013199","journal-title":"Transl Res"},{"issue":"9","key":"5298_CR32","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.1016\/j.joen.2011.05.022","volume":"37","author":"J Liao","year":"2011","unstructured":"Liao J et al (2011) Cells isolated from inflamed periapical tissue express mesenchymal stem cell markers and are highly osteogenic. J Endod 37(9):1217\u20131224","journal-title":"J Endod"},{"issue":"2","key":"5298_CR33","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1007\/s00441-005-0117-9","volume":"324","author":"GT Huang","year":"2006","unstructured":"Huang GT et al (2006) In vitro characterization of human dental pulp cells: various isolation methods and culturing environments. Cell Tissue Res 324(2):225\u2013236","journal-title":"Cell Tissue Res"},{"issue":"2","key":"5298_CR34","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1038\/nm1181","volume":"11","author":"MJ Martin","year":"2005","unstructured":"Martin MJ et al (2005) Human embryonic stem cells express an immunogenic nonhuman sialic acid. Nat Med 11(2):228\u2013232","journal-title":"Nat Med"},{"issue":"4","key":"5298_CR35","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1007\/s12015-011-9274-2","volume":"7","author":"A Aldahmash","year":"2011","unstructured":"Aldahmash A et al (2011) Human serum is as efficient as fetal bovine serum in supporting proliferation and differentiation of human multipotent stromal (mesenchymal) stem cells in vitro and in vivo. Stem Cell Rev Rep 7(4):860\u2013868","journal-title":"Stem Cell Rev Rep"},{"key":"5298_CR36","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.gien.2018.03.003","volume":"32","author":"M Tatullo","year":"2018","unstructured":"Tatullo M et al (2018) Human periapical cysts-mesenchymal stem cells cultured with allogenic human serum are a \u201cclinical-grade\u201d construct alternative to bovine fetal serum and indicated in the regeneration of endo-periodontal tissues. Giornale Italiano di Endodonzia 32:36\u201341","journal-title":"Giornale Italiano di Endodonzia"},{"issue":"4","key":"5298_CR37","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1002\/stem.312","volume":"28","author":"KC Russell","year":"2010","unstructured":"Russell KC et al (2010) In vitro high-capacity assay to quantify the clonal heterogeneity in trilineage potential of mesenchymal stem cells reveals a complex hierarchy of lineage commitment. Stem Cells 28(4):788\u2013798","journal-title":"Stem Cells"},{"issue":"5","key":"5298_CR38","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1007\/s12015-016-9674-4","volume":"12","author":"F Paduano","year":"2016","unstructured":"Paduano F et al (2016) CD146 Expression influences periapical cyst mesenchymal stem cell properties. Stem Cell Rev 12(5):592\u2013603","journal-title":"Stem Cell Rev"},{"issue":"12","key":"5298_CR39","doi-asserted-by":"publisher","first-page":"1791","DOI":"10.1016\/j.archoralbio.2013.09.012","volume":"58","author":"W Zhu","year":"2013","unstructured":"Zhu W et al (2013) Comparison of the properties of human CD146+ and CD146- periodontal ligament cells in response to stimulation with tumour necrosis factor alpha. Arch Oral Biol 58(12):1791\u20131803","journal-title":"Arch Oral Biol"},{"issue":"6","key":"5298_CR40","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1016\/j.joen.2019.03.009","volume":"45","author":"C Estrela","year":"2019","unstructured":"Estrela C et al (2019) Mesenchymal Stem Cell Marker Expression in Periapical Abscess. J Endod 45(6):716\u2013723","journal-title":"J Endod"},{"issue":"3","key":"5298_CR41","first-page":"713","volume":"29","author":"M Tatullo","year":"2015","unstructured":"Tatullo M et al (2015) Dental pulp stem cells and human periapical cyst mesenchymal stem cells in bone tissue regeneration: comparison of basal and osteogenic differentiated gene expression of a newly discovered mesenchymal stem cell lineage. J Biol Regul Homeost Agents 29(3):713\u2013718","journal-title":"J Biol Regul Homeost Agents"},{"issue":"6","key":"5298_CR42","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1177\/0022034515570316","volume":"94","author":"M Marrelli","year":"2015","unstructured":"Marrelli M, Paduano F, Tatullo M (2015) Human periapical cyst-mesenchymal stem cells differentiate into neuronal cells. J Dent Res 94(6):843\u2013852","journal-title":"J Dent Res"},{"issue":"1\u20132","key":"5298_CR43","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.mcn.2006.02.003","volume":"32","author":"M Sieber-Blum","year":"2006","unstructured":"Sieber-Blum M et al (2006) Characterization of epidermal neural crest stem cell (EPI-NCSC) grafts in the lesioned spinal cord. Mol Cell Neurosci 32(1\u20132):67\u201381","journal-title":"Mol Cell Neurosci"},{"issue":"4","key":"5298_CR44","doi-asserted-by":"publisher","first-page":"383","DOI":"10.4103\/0028-3886.117615","volume":"61","author":"K Venkatesh","year":"2013","unstructured":"Venkatesh K et al (2013) In vitro differentiation of cultured human CD34+ cells into astrocytes. Neurol India 61(4):383\u2013388","journal-title":"Neurol India"},{"issue":"4","key":"5298_CR45","doi-asserted-by":"publisher","first-page":"30","DOI":"10.32607\/20758251-2011-3-4-30-37","volume":"3","author":"NI Kalinina","year":"2011","unstructured":"Kalinina NI et al (2011) Mesenchymal stem cells in tissue growth and repair. Acta Naturae 3(4):30\u201337","journal-title":"Acta Naturae"},{"issue":"1","key":"5298_CR46","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1111\/odi.12086","volume":"20","author":"Z Li","year":"2014","unstructured":"Li Z et al (2014) Immunomodulatory properties of dental tissue-derived mesenchymal stem cells. Oral Dis 20(1):25\u201334","journal-title":"Oral Dis"},{"issue":"3","key":"5298_CR47","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1038\/sj.clpt.6100313","volume":"82","author":"DJ Prockop","year":"2007","unstructured":"Prockop DJ (2007) \"Stemness\" does not explain the repair of many tissues by mesenchymal stem\/multipotent stromal cells (MSCs). Clin Pharmacol Ther 82(3):241\u2013243","journal-title":"Clin Pharmacol Ther"},{"issue":"5","key":"5298_CR48","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1161\/01.RES.0000118601.37875.AC","volume":"94","author":"T Kinnaird","year":"2004","unstructured":"Kinnaird T et al (2004) Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms. Circ Res 94(5):678\u2013685","journal-title":"Circ Res"},{"key":"5298_CR49","doi-asserted-by":"publisher","first-page":"6516854","DOI":"10.1155\/2017\/6516854","volume":"2017","author":"Y Rubtsov","year":"2017","unstructured":"Rubtsov Y et al (2017) Molecular mechanisms of immunomodulation properties of mesenchymal stromal cells: a new insight into the role of ICAM-1. Stem Cells Int 2017:6516854","journal-title":"Stem Cells Int"},{"issue":"3","key":"5298_CR50","doi-asserted-by":"publisher","first-page":"e17899","DOI":"10.1371\/journal.pone.0017899","volume":"6","author":"T Lopatina","year":"2011","unstructured":"Lopatina T et al (2011) Adipose-derived stem cells stimulate regeneration of peripheral nerves: BDNF secreted by these cells promotes nerve healing and axon growth de novo. PLoS ONE 6(3):e17899","journal-title":"PLoS ONE"},{"issue":"6","key":"5298_CR51","doi-asserted-by":"publisher","first-page":"4672","DOI":"10.1007\/s12035-016-0011-3","volume":"54","author":"A Kumar","year":"2017","unstructured":"Kumar A et al (2017) Secretome cues modulate the neurogenic potential of bone marrow and dental stem cells. Mol Neurobiol 54(6):4672\u20134682","journal-title":"Mol Neurobiol"},{"issue":"10","key":"5298_CR52","doi-asserted-by":"publisher","first-page":"e109305","DOI":"10.1371\/journal.pone.0109305","volume":"9","author":"B Mead","year":"2014","unstructured":"Mead B et al (2014) Paracrine-mediated neuroprotection and neuritogenesis of axotomised retinal ganglion cells by human dental pulp stem cells: comparison with human bone marrow and adipose-derived mesenchymal stem cells. PLoS ONE 9(10):e109305","journal-title":"PLoS ONE"},{"key":"5298_CR53","doi-asserted-by":"publisher","first-page":"16295","DOI":"10.1038\/srep16295","volume":"5","author":"S Yamaguchi","year":"2015","unstructured":"Yamaguchi S et al (2015) Dental pulp-derived stem cell conditioned medium reduces cardiac injury following ischemia-reperfusion. Sci Rep 5:16295","journal-title":"Sci Rep"},{"key":"5298_CR54","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.archoralbio.2016.03.011","volume":"68","author":"SB Werle","year":"2016","unstructured":"Werle SB et al (2016) The effects of hypoxia on in vitro culture of dental-derived stem cells. Arch Oral Biol 68:13\u201320","journal-title":"Arch Oral Biol"},{"issue":"3","key":"5298_CR55","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.it.2011.11.004","volume":"33","author":"Y Shi","year":"2012","unstructured":"Shi Y et al (2012) How mesenchymal stem cells interact with tissue immune responses. Trends Immunol 33(3):136\u2013143","journal-title":"Trends Immunol"},{"issue":"4","key":"5298_CR56","doi-asserted-by":"publisher","first-page":"e10088","DOI":"10.1371\/journal.pone.0010088","volume":"5","author":"RS Waterman","year":"2010","unstructured":"Waterman RS et al (2010) A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. PLoS ONE 5(4):e10088","journal-title":"PLoS ONE"},{"issue":"7","key":"5298_CR57","doi-asserted-by":"publisher","first-page":"e101558","DOI":"10.1371\/journal.pone.0101558","volume":"9","author":"SH Hwang","year":"2014","unstructured":"Hwang SH et al (2014) Toll like receptor 3 & 4 responses of human turbinate derived mesenchymal stem cells: stimulation by double stranded RNA and lipopolysaccharide. PLoS ONE 9(7):e101558","journal-title":"PLoS ONE"},{"key":"5298_CR58","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.cellimm.2017.01.007","volume":"326","author":"MK Mekhemar","year":"2018","unstructured":"Mekhemar MK et al (2018) TLR-induced immunomodulatory cytokine expression by human gingival stem\/progenitor cells. Cell Immunol 326:60\u201367","journal-title":"Cell Immunol"},{"key":"5298_CR59","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.cellimm.2017.08.009","volume":"326","author":"DK Lee","year":"2018","unstructured":"Lee DK, Song SU (2018) Immunomodulatory mechanisms of mesenchymal stem cells and their therapeutic applications. Cell Immunol 326:68\u201376","journal-title":"Cell Immunol"},{"issue":"8","key":"5298_CR60","doi-asserted-by":"publisher","first-page":"1446","DOI":"10.1002\/stem.459","volume":"28","author":"J Tolar","year":"2010","unstructured":"Tolar J et al (2010) Concise review: hitting the right spot with mesenchymal stromal cells. Stem Cells 28(8):1446\u20131455","journal-title":"Stem Cells"},{"issue":"9","key":"5298_CR61","doi-asserted-by":"publisher","first-page":"604","DOI":"10.4252\/wjsc.v11.i9.604","volume":"11","author":"O Andrukhov","year":"2019","unstructured":"Andrukhov O et al (2019) Immunomodulatory properties of dental tissue-derived mesenchymal stem cells: implication in disease and tissue regeneration. World J Stem Cells 11(9):604\u2013617","journal-title":"World J Stem Cells"},{"key":"5298_CR62","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.cellimm.2016.08.008","volume":"310","author":"AT Ozdemir","year":"2016","unstructured":"Ozdemir AT et al (2016) The paracrine immunomodulatory interactions between the human dental pulp derived mesenchymal stem cells and CD4 T cell subsets. Cell Immunol 310:108\u2013115","journal-title":"Cell Immunol"},{"issue":"4","key":"5298_CR63","doi-asserted-by":"publisher","first-page":"1815","DOI":"10.1182\/blood-2004-04-1559","volume":"105","author":"S Aggarwal","year":"2005","unstructured":"Aggarwal S, Pittenger MF (2005) Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 105(4):1815\u20131822","journal-title":"Blood"},{"issue":"3","key":"5298_CR64","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1002\/stem.1881","volume":"33","author":"M Franquesa","year":"2015","unstructured":"Franquesa M et al (2015) Human adipose tissue-derived mesenchymal stem cells abrogate plasmablast formation and induce regulatory B cells independently of T helper cells. Stem Cells 33(3):880\u2013891","journal-title":"Stem Cells"},{"key":"5298_CR65","doi-asserted-by":"publisher","first-page":"103","DOI":"10.3389\/fcell.2017.00103","volume":"5","author":"M Tatullo","year":"2017","unstructured":"Tatullo M et al (2017) Potential use of human periapical cyst-mesenchymal stem cells (hPCy-MSCs) as a novel stem cell source for regenerative medicine applications. Front Cell Dev Biol 5:103","journal-title":"Front Cell Dev Biol"},{"issue":"7162","key":"5298_CR66","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1038\/nature06188","volume":"449","author":"AE Karnoub","year":"2007","unstructured":"Karnoub AE et al (2007) Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 449(7162):557\u2013563","journal-title":"Nature"},{"issue":"6","key":"5298_CR67","doi-asserted-by":"publisher","first-page":"e2563","DOI":"10.1371\/journal.pone.0002563","volume":"3","author":"KE Corcoran","year":"2008","unstructured":"Corcoran KE et al (2008) Mesenchymal stem cells in early entry of breast cancer into bone marrow. PLoS ONE 3(6):e2563","journal-title":"PLoS ONE"},{"issue":"37","key":"5298_CR68","doi-asserted-by":"publisher","first-page":"4343","DOI":"10.1038\/onc.2012.458","volume":"32","author":"WH Huang","year":"2013","unstructured":"Huang WH et al (2013) Mesenchymal stem cells promote growth and angiogenesis of tumors in mice. Oncogene 32(37):4343\u20134354","journal-title":"Oncogene"},{"key":"5298_CR69","doi-asserted-by":"publisher","first-page":"2298","DOI":"10.1038\/srep02298","volume":"3","author":"B Ljujic","year":"2013","unstructured":"Ljujic B et al (2013) Human mesenchymal stem cells creating an immunosuppressive environment and promote breast cancer in mice. Sci Rep 3:2298","journal-title":"Sci Rep"},{"issue":"3","key":"5298_CR70","doi-asserted-by":"publisher","first-page":"310","DOI":"10.2174\/15748928113089990040","volume":"8","author":"D Gjorgieva","year":"2013","unstructured":"Gjorgieva D, Zaidman N, Bosnakovski D (2013) Mesenchymal stem cells for anti-cancer drug delivery. Recent Pat Anticancer Drug Discov 8(3):310\u2013318","journal-title":"Recent Pat Anticancer Drug Discov"},{"key":"5298_CR71","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/s13058-015-0549-4","volume":"17","author":"L Lacerda","year":"2015","unstructured":"Lacerda L et al (2015) Mesenchymal stem cells mediate the clinical phenotype of inflammatory breast cancer in a preclinical model. Breast Cancer Res 17:42","journal-title":"Breast Cancer Res"},{"issue":"10","key":"5298_CR72","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.1038\/s41419-018-0949-3","volume":"9","author":"N He","year":"2018","unstructured":"He N et al (2018) MSCs inhibit tumor progression and enhance radiosensitivity of breast cancer cells by down-regulating Stat3 signaling pathway. Cell Death Dis 9(10):1026","journal-title":"Cell Death Dis"},{"issue":"1","key":"5298_CR73","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1186\/s13287-018-0831-3","volume":"9","author":"H Salehi","year":"2018","unstructured":"Salehi H et al (2018) Dental pulp stem cells used to deliver the anticancer drug paclitaxel. Stem Cell Res Ther 9(1):103","journal-title":"Stem Cell Res Ther"},{"issue":"6","key":"5298_CR74","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1016\/j.tice.2017.10.003","volume":"49","author":"A Dogan","year":"2017","unstructured":"Dogan A et al (2017) Dental pulp stem cells (DPSCs) increase prostate cancer cell proliferation and migration under in vitro conditions. Tissue Cell 49(6):711\u2013718","journal-title":"Tissue Cell"},{"issue":"9","key":"5298_CR75","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1111\/j.1365-2591.2011.01877.x","volume":"44","author":"FJ Rodriguez-Lozano","year":"2011","unstructured":"Rodriguez-Lozano FJ et al (2011) Mesenchymal stem cells derived from dental tissues. Int Endod J 44(9):800\u2013806","journal-title":"Int Endod J"},{"issue":"5","key":"5298_CR76","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1517\/14712598.3.5.705","volume":"3","author":"JM Gimble","year":"2003","unstructured":"Gimble JM (2003) Adipose tissue-derived therapeutics. Expert Opin Biol Ther 3(5):705\u2013713","journal-title":"Expert Opin Biol Ther"},{"issue":"1","key":"5298_CR77","doi-asserted-by":"publisher","first-page":"23","DOI":"10.4161\/org.6048","volume":"4","author":"AJ Rosenbaum","year":"2008","unstructured":"Rosenbaum AJ, Grande DA, Dines JS (2008) The use of mesenchymal stem cells in tissue engineering: a global assessment. Organogenesis 4(1):23\u201327","journal-title":"Organogenesis"},{"issue":"3","key":"5298_CR78","doi-asserted-by":"publisher","first-page":"269","DOI":"10.4067\/S0716-97602012000300008","volume":"45","author":"FE Figueroa","year":"2012","unstructured":"Figueroa FE et al (2012) Mesenchymal stem cell treatment for autoimmune diseases: a critical review. Biol Res 45(3):269\u2013277","journal-title":"Biol Res"},{"issue":"11","key":"5298_CR79","doi-asserted-by":"publisher","first-page":"1815","DOI":"10.1902\/jop.2009.090249","volume":"80","author":"SH Kim","year":"2009","unstructured":"Kim SH et al (2009) Alveolar bone regeneration by transplantation of periodontal ligament stem cells and bone marrow stem cells in a canine peri-implant defect model: a pilot study. J Periodontol 80(11):1815\u20131823","journal-title":"J Periodontol"},{"issue":"8","key":"5298_CR80","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1080\/09205063.2017.1301770","volume":"28","author":"F Paduano","year":"2017","unstructured":"Paduano F et al (2017) Decellularized bone extracellular matrix and human dental pulp stem cells as a construct for bone regeneration. J Biomater Sci Polym Ed 28(8):730\u2013748","journal-title":"J Biomater Sci Polym Ed"},{"issue":"2","key":"5298_CR81","doi-asserted-by":"publisher","first-page":"e0148225","DOI":"10.1371\/journal.pone.0148225","volume":"11","author":"F Paduano","year":"2016","unstructured":"Paduano F et al (2016) Odontogenic differentiation of human dental pulp stem cells on hydrogel scaffolds derived from decellularized bone extracellular matrix and collagen type I. PLoS ONE 11(2):e0148225","journal-title":"PLoS ONE"},{"issue":"4","key":"5298_CR82","doi-asserted-by":"publisher","first-page":"597","DOI":"10.3390\/ma12040597","volume":"12","author":"M Tatullo","year":"2019","unstructured":"Tatullo M et al (2019) PLA-based mineral-doped scaffolds seeded with human periapical cyst-derived MSCs: a promising tool for regenerative healing in dentistry. Materials (Basel) 12(4):597","journal-title":"Materials (Basel)"},{"issue":"3","key":"5298_CR83","doi-asserted-by":"publisher","first-page":"5338","DOI":"10.3390\/ijms14035338","volume":"14","author":"C Corrado","year":"2013","unstructured":"Corrado C et al (2013) Exosomes as intercellular signaling organelles involved in health and disease: basic science and clinical applications. Int J Mol Sci 14(3):5338\u20135366","journal-title":"Int J Mol Sci"},{"issue":"12","key":"5298_CR84","doi-asserted-by":"publisher","first-page":"358","DOI":"10.3390\/brainsci9120358","volume":"9","author":"M Tatullo","year":"2019","unstructured":"Tatullo M et al (2019) Human periapical cyst-derived stem cells can be a smart \"Lab-on-A-Cell\" to investigate neurodegenerative diseases and the related alteration of the exosomes' content. Brain Sci 9(12):358","journal-title":"Brain Sci"},{"key":"5298_CR85","first-page":"CD00511","volume":"10","author":"M Del Fabbro","year":"2016","unstructured":"Del Fabbro M et al (2016) Endodontic procedures for retreatment of periapical lesions. Cochrane Database Syst Rev 10:CD00511","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"5298_CR86","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1007\/s00441-003-0832-z","volume":"315","author":"H Maeda","year":"2004","unstructured":"Maeda H et al (2004) Human periapical granulation tissue contains osteogenic cells. Cell Tissue Res 315(2):203\u2013208","journal-title":"Cell Tissue Res"},{"issue":"2","key":"5298_CR87","doi-asserted-by":"publisher","first-page":"E23","DOI":"10.1111\/j.1399-0012.2009.01137.x","volume":"24","author":"F Agha-Hosseini","year":"2010","unstructured":"Agha-Hosseini F et al (2010) In vitro isolation of stem cells derived from human dental pulp. Clin Transplant 24(2):E23\u2013E28","journal-title":"Clin Transplant"},{"issue":"6","key":"5298_CR88","doi-asserted-by":"publisher","first-page":"1891","DOI":"10.1089\/ten.tea.2009.0732","volume":"16","author":"Y Yamada","year":"2010","unstructured":"Yamada Y et al (2010) A feasibility of useful cell-based therapy by bone regeneration with deciduous tooth stem cells, dental pulp stem cells, or bone-marrow-derived mesenchymal stem cells for clinical study using tissue engineering technology. Tissue Eng A 16(6):1891\u20131900","journal-title":"Tissue Eng A"},{"issue":"3","key":"5298_CR89","doi-asserted-by":"publisher","first-page":"4666","DOI":"10.3390\/ijms16034666","volume":"16","author":"L Ferroni","year":"2015","unstructured":"Ferroni L et al (2015) A hyaluronan-based scaffold for the in vitro construction of dental pulp-like tissue. Int J Mol Sci 16(3):4666\u20134681","journal-title":"Int J Mol Sci"},{"issue":"1","key":"5298_CR90","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1186\/s13023-018-0843-1","volume":"13","author":"PN Almeida","year":"2018","unstructured":"Almeida PN et al (2018) Increased extracellular matrix deposition during chondrogenic differentiation of dental pulp stem cells from individuals with neurofibromatosis type 1: an in vitro 2D and 3D study. Orphanet J Rare Dis 13(1):98","journal-title":"Orphanet J Rare Dis"},{"issue":"6","key":"5298_CR91","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1007\/s10571-014-0063-8","volume":"34","author":"X Feng","year":"2014","unstructured":"Feng X et al (2014) 3D porous chitosan scaffolds suit survival and neural differentiation of dental pulp stem cells. Cell Mol Neurobiol 34(6):859\u2013870","journal-title":"Cell Mol Neurobiol"},{"issue":"3","key":"5298_CR92","first-page":"235","volume":"11","author":"AR Navabazam","year":"2013","unstructured":"Navabazam AR et al (2013) Characterization of mesenchymal stem cells from human dental pulp, preapical follicle and periodontal ligament. Iran J Reprod Med 11(3):235\u2013242","journal-title":"Iran J Reprod Med"},{"issue":"10","key":"5298_CR93","doi-asserted-by":"publisher","first-page":"3856","DOI":"10.1016\/j.actbio.2010.04.009","volume":"6","author":"J Wang","year":"2010","unstructured":"Wang J et al (2010) The odontogenic differentiation of human dental pulp stem cells on nanofibrous poly(L-lactic acid) scaffolds in vitro and in vivo. Acta Biomater 6(10):3856\u20133863","journal-title":"Acta Biomater"},{"issue":"7","key":"5298_CR94","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1634\/stemcells.2007-0979","volume":"26","author":"A Arthur","year":"2008","unstructured":"Arthur A et al (2008) Adult human dental pulp stem cells differentiate toward functionally active neurons under appropriate environmental cues. Stem Cells 26(7):1787\u20131795","journal-title":"Stem Cells"},{"issue":"1","key":"5298_CR95","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1007\/s00418-009-0646-5","volume":"133","author":"E Karaoz","year":"2010","unstructured":"Karaoz E et al (2010) Isolation and in vitro characterisation of dental pulp stem cells from natal teeth. Histochem Cell Biol 133(1):95\u2013112","journal-title":"Histochem Cell Biol"},{"issue":"6","key":"5298_CR96","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1016\/j.archoralbio.2012.11.004","volume":"58","author":"M Gosau","year":"2013","unstructured":"Gosau M et al (2013) Comparison of the differentiation potential of neural crest derived progenitor cells from apical papilla (dNC-PCs) and stem cells from exfoliated deciduous teeth (SHED) into mineralising cells. Arch Oral Biol 58(6):699\u2013706","journal-title":"Arch Oral Biol"},{"key":"5298_CR97","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1007\/s12031-013-0046-0","volume":"51","author":"A Jarmalaviciute","year":"2013","unstructured":"Jarmalaviciute A et al (2013) A new experimental model for neuronal and glial differentiation using stem cells derived from human exfoliated deciduous teeth. J Mol Neurosci 51:307\u2013317","journal-title":"J Mol Neurosci"},{"issue":"1","key":"5298_CR98","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/scrt5","volume":"1","author":"T Yamaza","year":"2010","unstructured":"Yamaza T et al (2010) Immunomodulatory properties of stem cells from human exfoliated deciduous teeth. Stem Cell Res Ther 1(1):5","journal-title":"Stem Cell Res Ther"},{"issue":"8","key":"5298_CR99","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1016\/j.joen.2008.04.009","volume":"34","author":"MM Cordeiro","year":"2008","unstructured":"Cordeiro MM et al (2008) Dental pulp tissue engineering with stem cells from exfoliated deciduous teeth. J Endod 34(8):962\u2013969","journal-title":"J Endod"},{"key":"5298_CR100","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1186\/s13287-015-0154-6","volume":"6","author":"T Yamaza","year":"2015","unstructured":"Yamaza T et al (2015) In vivo hepatogenic capacity and therapeutic potential of stem cells from human exfoliated deciduous teeth in liver fibrosis in mice. Stem Cell Res Ther 6:171","journal-title":"Stem Cell Res Ther"},{"issue":"3","key":"5298_CR101","doi-asserted-by":"publisher","first-page":"1408","DOI":"10.1167\/iovs.09-4029","volume":"51","author":"JA Gomes","year":"2010","unstructured":"Gomes JA et al (2010) Corneal reconstruction with tissue-engineered cell sheets composed of human immature dental pulp stem cells. Invest Ophthalmol Vis Sci 51(3):1408\u20131414","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"4","key":"5298_CR102","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1111\/j.1600-0765.2006.00870.x","volume":"41","author":"K Nagatomo","year":"2006","unstructured":"Nagatomo K et al (2006) Stem cell properties of human periodontal ligament cells. J Periodontal Res 41(4):303\u2013310","journal-title":"J Periodontal Res"},{"issue":"2","key":"5298_CR103","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1111\/jcmm.12192","volume":"18","author":"AB Vasandan","year":"2014","unstructured":"Vasandan AB et al (2014) Functional differences in mesenchymal stromal cells from human dental pulp and periodontal ligament. J Cell Mol Med 18(2):344\u2013354","journal-title":"J Cell Mol Med"},{"issue":"10","key":"5298_CR104","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1089\/ten.tec.2014.0603","volume":"21","author":"S Sowmya","year":"2015","unstructured":"Sowmya S et al (2015) Periodontal specific differentiation of dental follicle stem cells into osteoblast, fibroblast, and cementoblast. Tissue Eng C 21(10):1044\u20131058","journal-title":"Tissue Eng C"},{"issue":"2\u20133","key":"5298_CR105","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1080\/03008200290001023","volume":"43","author":"K Handa","year":"2002","unstructured":"Handa K et al (2002) Progenitor cells from dental follicle are able to form cementum matrix in vivo. Connect Tissue Res 43(2\u20133):406\u2013408","journal-title":"Connect Tissue Res"},{"issue":"4","key":"5298_CR106","doi-asserted-by":"publisher","first-page":"567","DOI":"10.7150\/ijms.30801","volume":"16","author":"T Fu","year":"2019","unstructured":"Fu T et al (2019) Matrigel scaffolding enhances BMP9-induced bone formation in dental follicle stem\/precursor cells. Int J Med Sci 16(4):567\u2013575","journal-title":"Int J Med Sci"},{"issue":"1","key":"5298_CR107","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/S1348-8643(07)80011-5","volume":"4","author":"S Abe","year":"2007","unstructured":"Abe S, Yamaguchi S, Amagasa T (2007) Multilineage cells from apical pulp of human tooth with immature apex. Oral Sci Int 4(1):45\u201358","journal-title":"Oral Sci Int"},{"issue":"10","key":"5298_CR108","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1042\/CBI20110506","volume":"36","author":"S Abe","year":"2012","unstructured":"Abe S et al (2012) Neural crest stem cell property of apical pulp cells derived from human developing tooth. Cell Biol Int 36(10):927\u2013936","journal-title":"Cell Biol Int"},{"issue":"5\u20136","key":"5298_CR109","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1089\/ten.tea.2014.0058","volume":"21","author":"C Yuan","year":"2015","unstructured":"Yuan C et al (2015) Coculture of stem cells from apical papilla and human umbilical vein endothelial cell under hypoxia increases the formation of three-dimensional vessel-like structures in vitro. Tissue Eng A 21(5\u20136):1163\u20131172","journal-title":"Tissue Eng A"},{"issue":"23\u201324","key":"5298_CR110","doi-asserted-by":"publisher","first-page":"3089","DOI":"10.1089\/ten.tea.2013.0347","volume":"20","author":"JF de Almeida","year":"2014","unstructured":"de Almeida JF et al (2014) Stem cells of the apical papilla regulate trigeminal neurite outgrowth and targeting through a BDNF-dependent mechanism. Tissue Eng A 20(23\u201324):3089\u20133100","journal-title":"Tissue Eng A"},{"key":"5298_CR111","doi-asserted-by":"publisher","first-page":"1556","DOI":"10.1016\/j.archoralbio.2013.06.018","volume":"58","author":"A Bakopoulou","year":"2013","unstructured":"Bakopoulou A et al (2013) Comparative characterization of STRO-1neg\/CD146pos and STRO-1pos\/CD146pos apical papilla stem cells enriched with flow cytometry. Arch Oral Biol 58:1556\u20131568","journal-title":"Arch Oral Biol"},{"issue":"4","key":"5298_CR112","doi-asserted-by":"publisher","first-page":"617","DOI":"10.2217\/rme.10.30","volume":"5","author":"DJ Alongi","year":"2010","unstructured":"Alongi DJ et al (2010) Stem\/progenitor cells from inflamed human dental pulp retain tissue regeneration potential. Regen Med 5(4):617\u2013631","journal-title":"Regen Med"},{"issue":"10","key":"5298_CR113","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1177\/0022034512458690","volume":"91","author":"Y Zhao","year":"2012","unstructured":"Zhao Y et al (2012) Fas ligand regulates the immunomodulatory properties of dental pulp stem cells. J Dent Res 91(10):948\u2013954","journal-title":"J Dent Res"},{"issue":"3","key":"5298_CR114","doi-asserted-by":"publisher","first-page":"95","DOI":"10.3727\/215517914X680038","volume":"7","author":"MA Barros","year":"2015","unstructured":"Barros MA et al (2015) Immature dental pulp stem cells showed renotropic and pericyte-like properties in acute renal failure in rats. Cell Med 7(3):95\u2013108","journal-title":"Cell Med"},{"key":"5298_CR115","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/1479-5876-6-35","volume":"6","author":"I Kerkis","year":"2008","unstructured":"Kerkis I et al (2008) Early transplantation of human immature dental pulp stem cells from baby teeth to golden retriever muscular dystrophy (GRMD) dogs: Local or systemic? J Transl Med 6:35","journal-title":"J Transl Med"},{"issue":"1","key":"5298_CR116","doi-asserted-by":"publisher","first-page":"20","DOI":"10.5966\/sctm.2015-0163","volume":"5","author":"E Cianci","year":"2016","unstructured":"Cianci E et al (2016) Human periodontal stem cells release specialized proresolving mediators and carry immunomodulatory and prohealing properties regulated by lipoxins. Stem Cells Transl Med 5(1):20\u201332","journal-title":"Stem Cells Transl Med"},{"issue":"1","key":"5298_CR117","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1111\/jre.12378","volume":"52","author":"C Shin","year":"2017","unstructured":"Shin C et al (2017) Human periodontal ligament stem cells suppress T-cell proliferation via down-regulation of non-classical major histocompatibility complex-like glycoprotein CD1b on dendritic cells. J Periodontal Res 52(1):135\u2013146","journal-title":"J Periodontal Res"},{"issue":"6","key":"5298_CR118","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1111\/cea.13126","volume":"48","author":"D Genc","year":"2018","unstructured":"Genc D et al (2018) Dental follicle mesenchymal stem cells down-regulate Th2-mediated immune response in asthmatic patients mononuclear cells. Clin Exp Allergy 48(6):663\u2013678","journal-title":"Clin Exp Allergy"},{"key":"5298_CR119","first-page":"9159605","volume":"2019","author":"T Zhou","year":"2019","unstructured":"Zhou T et al (2019) Dental follicle cells: roles in development and beyond. Stem Cells Int 2019:9159605","journal-title":"Stem Cells Int"},{"key":"5298_CR120","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1186\/s12974-015-0451-0","volume":"12","author":"C Ulusoy","year":"2015","unstructured":"Ulusoy C et al (2015) Dental follicle mesenchymal stem cell administration ameliorates muscle weakness in MuSK-immunized mice. J Neuroinflammation 12:231","journal-title":"J Neuroinflammation"},{"issue":"5","key":"5298_CR121","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1159\/000276589","volume":"191","author":"G Ding","year":"2010","unstructured":"Ding G et al (2010) Suppression of T cell proliferation by root apical papilla stem cells in vitro. Cells Tissues Organs 191(5):357\u2013364","journal-title":"Cells Tissues Organs"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-020-05298-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11033-020-05298-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-020-05298-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T20:22:11Z","timestamp":1650399731000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11033-020-05298-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,6]]},"references-count":121,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["5298"],"URL":"https:\/\/doi.org\/10.1007\/s11033-020-05298-6","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,6]]},"assertion":[{"value":"23 October 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 January 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 February 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declares that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}