{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T13:24:57Z","timestamp":1793021097822,"version":"4.5.0"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2020,11,15]],"date-time":"2020-11-15T00:00:00Z","timestamp":1605398400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,11,15]],"date-time":"2020-11-15T00:00:00Z","timestamp":1605398400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1007\/s11033-020-05989-0","type":"journal-article","created":{"date-parts":[[2020,11,15]],"date-time":"2020-11-15T11:02:31Z","timestamp":1605438151000},"page":"9615-9625","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Origanum vulgare essential oil: antibacterial activities and synergistic effect with polymyxin B against multidrug-resistant Acinetobacter baumannii"],"prefix":"10.1007","volume":"47","author":[{"given":"Su\u00e9len Cavalheiro","family":"Amaral","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz Bohns","family":"Pruski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stella Buchhorn","family":"de Freitas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzane Olachea","family":"Allend","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos Roberto Alves","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Cl\u00f3vis","family":"Moreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela Isabel Brayer","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio Sergio Varela","family":"Junior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3604-0832","authenticated-orcid":false,"given":"Daiane Drawanz","family":"Hartwig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,11,15]]},"reference":[{"key":"5989_CR1","unstructured":"World Health Organization (2017) Prioritization of pathogens to guide discovery, research and development of new antibiotics for drug-resistant bacterial infections, including tuberculosis"},{"key":"5989_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2015.03.001","author":"A Potron","year":"2015","unstructured":"Potron A, Poirel L, Nordmann P (2015) Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii: mechanisms and epidemiology. Int J Antimicrob Agents. https:\/\/doi.org\/10.1016\/j.ijantimicag.2015.03.001","journal-title":"Int J Antimicrob Agents"},{"key":"5989_CR3","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2016.5538","author":"SZ Xiao","year":"2016","unstructured":"Xiao SZ, Chu HQ, Han LZ et al (2016) Resistant mechanisms and molecular epidemiology of imipenem-resistant Acinetobacter baumannii. Mol Med Rep. https:\/\/doi.org\/10.3892\/mmr.2016.5538","journal-title":"Mol Med Rep"},{"key":"5989_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2014.10.006","author":"MD Alc\u00e1ntar-Curiel","year":"2014","unstructured":"Alc\u00e1ntar-Curiel MD, Garc\u00eda-Torres LF, Gonz\u00e1lez-Ch\u00e1vez MI et al (2014) Molecular mechanisms associated with nosocomial carbapenem-resistant Acinetobacter baumannii in Mexico. Arch Med Res. https:\/\/doi.org\/10.1016\/j.arcmed.2014.10.006","journal-title":"Arch Med Res"},{"key":"5989_CR5","doi-asserted-by":"publisher","DOI":"10.3390\/ph4020419","author":"SR Schlesinger","year":"2011","unstructured":"Schlesinger SR, Lahousse MJ, Foster TO, Kim SK (2011) Metallo-\u03b2-Lactamases and aptamer-based inhibition. Pharmaceuticals. https:\/\/doi.org\/10.3390\/ph4020419","journal-title":"Pharmaceuticals"},{"key":"5989_CR6","doi-asserted-by":"publisher","DOI":"10.5812\/pedinfect.15439","author":"M Noori","year":"2014","unstructured":"Noori M, Karimi A, Fallah F et al (2014) High prevalence of Metallo beta-lactamase-producing Acinetobacter baumannii isolated from two hospitals of Tehran, Iran. Arch Pediatr Infect Dis. https:\/\/doi.org\/10.5812\/pedinfect.15439","journal-title":"Arch Pediatr Infect Dis"},{"key":"5989_CR7","doi-asserted-by":"publisher","DOI":"10.1002\/pro.697","author":"D King","year":"2011","unstructured":"King D, Strynadka N (2011) Crystal structure of New Delhi metallo-\u03b2-lactamase reveals the molecular basis for antibiotic resistance. Protein Sci. https:\/\/doi.org\/10.1002\/pro.697","journal-title":"Protein Sci"},{"key":"5989_CR8","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00064-16","author":"L Poirel","year":"2017","unstructured":"Poirel L, Jayol A, Nordmanna P (2017) Polymyxins: antibacterial activity, susceptibility testing, and resistance mechanisms encoded by plasmids or chromosomes. Clin Microbiol Rev. https:\/\/doi.org\/10.1128\/CMR.00064-16","journal-title":"Clin Microbiol Rev"},{"key":"5989_CR9","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00760","author":"S Scandorieiro","year":"2016","unstructured":"Scandorieiro S, de Camargo LC, Lancheros CAC et al (2016) Synergistic and the additive effect of oregano essential oil and biological silver nanoparticles against multidrug-resistant bacterial strains. Front Microbiol. https:\/\/doi.org\/10.3389\/fmicb.2016.00760","journal-title":"Front Microbiol"},{"key":"5989_CR10","doi-asserted-by":"crossref","unstructured":"Sharifi\u2010Rad M, Berkay Y\u0131lmaz Y, Antika G, Salehi B, Tumer TB, Kulandaisamy Venil C, Das G, Patra JK, Karazhan N, Akram M, Iqbal M (2020) Phytochemical constituents, biological activities, and health-promoting effects of the genus Origanum. Phyther Res","DOI":"10.1002\/ptr.6785"},{"key":"5989_CR11","doi-asserted-by":"publisher","DOI":"10.2298\/ABS1302639S","author":"D Stojkovi\u0107","year":"2013","unstructured":"Stojkovi\u0107 D, Glamo\u010dlija J, \u0106iri\u0107 A et al (2013) Investigation on antibacterial synergism of Origanum vulgare and Thymus vulgaris essential oils. Arch Biol Sci. https:\/\/doi.org\/10.2298\/ABS1302639S","journal-title":"Arch Biol Sci"},{"key":"5989_CR12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2006.01.004","author":"N Woodford","year":"2006","unstructured":"Woodford N, Ellington MJ, Coelho JM et al (2006) Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp. Int J Antimicrob Agents. https:\/\/doi.org\/10.1016\/j.ijantimicag.2006.01.004","journal-title":"Int J Antimicrob Agents"},{"key":"5989_CR13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2007.01819.x","author":"PG Higgins","year":"2007","unstructured":"Higgins PG, Wisplinghoff H, Krut O, Seifert H (2007) A PCR-based method to differentiate between Acinetobacter baumannii and Acinetobacter genomic species 13TU. Clin Microbiol Infect. https:\/\/doi.org\/10.1111\/j.1469-0691.2007.01819.x","journal-title":"Clin Microbiol Infect"},{"key":"5989_CR14","doi-asserted-by":"publisher","DOI":"10.1016\/j.femsle.2005.01.005","author":"H Segal","year":"2005","unstructured":"Segal H, Garny S, Elisha BG (2005) Is ISABA-1 customized for Acinetobacter? FEMS Microbiol Lett. https:\/\/doi.org\/10.1016\/j.femsle.2005.01.005","journal-title":"FEMS Microbiol Lett"},{"key":"5989_CR15","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1128\/jcm.7.1.102-103.1978","volume":"7","author":"W Hodge","year":"1978","unstructured":"Hodge W, Ciak J, Tramont EC (1978) Simple method for detection of penicillinase-producing Neisseria gonorrhoeae. J Clin Microbiol 7:102","journal-title":"J Clin Microbiol"},{"key":"5989_CR16","doi-asserted-by":"publisher","unstructured":"Clinical Laboratory Standards Institute (2015) Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically\u202f; Approved Standard \u2014Tenth Edition. CLSI document M07-A9. Clin Lab Standars Inst. https:\/\/doi.org\/10.4103\/0976-237X.91790","DOI":"10.4103\/0976-237X.91790"},{"key":"5989_CR17","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.10.4623-4629.2003","author":"K Lee","year":"2003","unstructured":"Lee K, Lim YS, Yong D et al (2003) Evaluation of the Hodge test and the imipenem-EDTA double-disk synergy test for differentiating metallo-\u03b2-lactamase-producing isolates of Pseudomonas spp. and Acinetobacter spp. J Clin Microbiol. https:\/\/doi.org\/10.1128\/JCM.41.10.4623-4629.2003","journal-title":"J Clin Microbiol"},{"key":"5989_CR18","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.10.3798-3801.2002","author":"D Yong","year":"2002","unstructured":"Yong D, Lee K, Yum JH et al (2002) Imipenem-EDTA disk method for differentiation of metallo-\u03b2-lactamase-producing clinical isolates of Pseudomonas spp. and Acinetobacter spp. J Clin Microbiol. https:\/\/doi.org\/10.1128\/JCM.40.10.3798-3801.2002","journal-title":"J Clin Microbiol"},{"key":"5989_CR19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2016.11.031","author":"W Wei","year":"2017","unstructured":"Wei W, Yang H (2017) Synergy against extensively drug-resistant Acinetobacter baumannii in vitro by two old antibiotics: colistin and chloramphenicol. Int J Antimicrob Agents. https:\/\/doi.org\/10.1016\/j.ijantimicag.2016.11.031","journal-title":"Int J Antimicrob Agents"},{"key":"5989_CR20","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01563-18","author":"M Lescat","year":"2019","unstructured":"Lescat M, Poirel L, Tinguely C, Nordmann P (2019) A Resazurin Reduction-Based Assay for Rapid Detection of Polymyxin Resistance in Acinetobacter baumannii and Pseudomonas aeruginosa. J Clin Microbiol. https:\/\/doi.org\/10.1128\/JCM.01563-18","journal-title":"J Clin Microbiol"},{"key":"5989_CR21","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2005.07.009","author":"T Hallap","year":"2006","unstructured":"Hallap T, Nagy S, Jaakma \u00dc et al (2006) Usefulness of a triple fluorochrome combination Merocyanine 540\/Yo-Pro 1\/Hoechst 33342 in assessing membrane stability of viable frozen-thawed spermatozoa from Estonian Holstein AI bulls. Theriogenology. https:\/\/doi.org\/10.1016\/j.theriogenology.2005.07.009","journal-title":"Theriogenology"},{"key":"5989_CR22","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1345\/aph.1P084","volume":"45","author":"JS Esterly","year":"2011","unstructured":"Esterly JS, Richardson CL, Eltoukhy NS et al (2011) Genetic mechanisms of antimicrobial resistance of Acinetobacter baumannii. Ann Pharmacother 45:218","journal-title":"Ann Pharmacother"},{"key":"5989_CR23","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1038\/nrmicro3380","volume":"13","author":"JMA Blair","year":"2015","unstructured":"Blair JMA, Webber MA, Baylay AJ et al (2015) Molecular mechanisms of antibiotic resistance. Nat Rev Microbiol 13:42","journal-title":"Nat Rev Microbiol"},{"key":"5989_CR24","first-page":"276","volume":"46","author":"LE Prestes-Carneiro","year":"2015","unstructured":"Prestes-Carneiro LE, Azevedo AM, Nakashima MA et al (2015) Frequency and antimicrobial susceptibility of pathogens at tertiary public hospital, Sao Paulo, Brazil. Southeast Asian J Trop Med Public Health 46:276","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"5989_CR25","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/1839190","author":"EA Sheck","year":"2017","unstructured":"Sheck EA, Edelstein MV, Sukhorukova MV et al (2017) Epidemiology and genetic diversity of colistin nonsusceptible nosocomial acinetobacter baumannii strains from Russia for 2013\u20132014. Can J Infect Dis Med Microbiol. https:\/\/doi.org\/10.1155\/2017\/1839190","journal-title":"Can J Infect Dis Med Microbiol"},{"key":"5989_CR26","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03570.x","author":"AP Magiorakos","year":"2012","unstructured":"Magiorakos AP, Srinivasan A, Carey RB et al (2012) Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect. https:\/\/doi.org\/10.1111\/j.1469-0691.2011.03570.x","journal-title":"Clin Microbiol Infect"},{"key":"5989_CR27","doi-asserted-by":"publisher","DOI":"10.5402\/2013\/154921","author":"H Kabbaj","year":"2013","unstructured":"Kabbaj H, Seffar M, Belefquih B et al (2013) Prevalence of Metallo- \u03b2 -Lactamases Producing Acinetobacter baumannii in a Moroccan Hospital. ISRN Infect Dis. https:\/\/doi.org\/10.5402\/2013\/154921","journal-title":"ISRN Infect Dis"},{"key":"5989_CR28","doi-asserted-by":"publisher","DOI":"10.1016\/0924-8579(93)90045-7","author":"R Paton","year":"1993","unstructured":"Paton R, Miles RS, Hood J et al (1993) ARI 1: \u03b2-lactamase-mediated imipenem resistance in Acinetobacter baumannii. Int J Antimicrob Agents. https:\/\/doi.org\/10.1016\/0924-8579(93)90045-7","journal-title":"Int J Antimicrob Agents"},{"key":"5989_CR29","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1586\/14787210.2013.811924","volume":"11","author":"JJ Maya","year":"2013","unstructured":"Maya JJ, Ruiz SJ, Blanco VM et al (2013) Current status of carbapenemases in Latin America. Expert Rev Anti Infect Ther 11:657","journal-title":"Expert Rev Anti Infect Ther"},{"key":"5989_CR30","first-page":"276","volume":"42","author":"JA Labarca","year":"2016","unstructured":"Labarca JA, Salles MJC, Seas C, Guzm\u00e1n-Blanco M (2016) Carbapenem resistance in Pseudomonas aeruginosa and Acinetobacter baumannii in the nosocomial setting in Latin America. Crit Rev Microbiol 42:276","journal-title":"Crit Rev Microbiol"},{"key":"5989_CR31","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2006.00195.x","author":"JF Turton","year":"2006","unstructured":"Turton JF, Ward ME, Woodford N et al (2006) The role of ISAba1 in expression of OXA carbapenemase genes in Acinetobacter baumannii. FEMS Microbiol Lett. https:\/\/doi.org\/10.1111\/j.1574-6968.2006.00195.x","journal-title":"FEMS Microbiol Lett"},{"key":"5989_CR32","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00764-10","author":"TL Chen","year":"2010","unstructured":"Chen TL, Lee YT, Kuo SC et al (2010) Emergence and distribution of plasmids bearing the blaOXA-51- like gene with an upstream ISAba1 in carbapenem-resistant Acinetobacter baumannii isolates in Taiwan. Antimicrob Agents Chemother. https:\/\/doi.org\/10.1128\/AAC.00764-10","journal-title":"Antimicrob Agents Chemother"},{"key":"5989_CR33","doi-asserted-by":"publisher","DOI":"10.3402\/mehd.v26.23289","author":"M Fournomiti","year":"2015","unstructured":"Fournomiti M, Kimbaris A, Mantzourani I et al (2015) Antimicrobial activity of essential oils of cultivated oregano ( Origanum vulgare ), sage ( Salvia officinalis ), and thyme ( Thymus vulgaris ) against clinical isolates of Escherichia coli, Klebsiella oxytoca, and Klebsiella pneumoniae. Microb Ecol Heal Dis. https:\/\/doi.org\/10.3402\/mehd.v26.23289","journal-title":"Microb Ecol Heal Dis"},{"key":"5989_CR34","doi-asserted-by":"publisher","DOI":"10.1590\/0037-8682-0502-2018","author":"NG Vasconcelos","year":"2019","unstructured":"Vasconcelos NG, Croda J, Silva KE et al (2019) Origanum vulgare l Essential oil inhibits the growth of carbapenem-resistant gram-negative bacteria. Rev Soc Bras Med Trop. https:\/\/doi.org\/10.1590\/0037-8682-0502-2018","journal-title":"Rev Soc Bras Med Trop"},{"key":"5989_CR35","doi-asserted-by":"publisher","DOI":"10.1590\/s0101-20612010000500021","author":"JPL Silva","year":"2010","unstructured":"Silva JPL, Duarte-Almeida JM, Perez DV, de Franco BDGM (2010) \u00d3leo essencial de or\u00e9gano: interfer\u00eancia da composi\u00e7\u00e3o qu\u00edmica na atividade frente a Salmonella Enteritidis. Ci\u00eancia e Tecnol Aliment. https:\/\/doi.org\/10.1590\/s0101-20612010000500021","journal-title":"Ci\u00eancia e Tecnol Aliment"},{"key":"5989_CR36","doi-asserted-by":"publisher","DOI":"10.2174\/092986710792231996","author":"A Rosato","year":"2010","unstructured":"Rosato A, Piarulli M, Corbo F et al (2010) In vitro synergistic action of certain combinations of gentamicin and essential oils. Curr Med Chem. https:\/\/doi.org\/10.2174\/092986710792231996","journal-title":"Curr Med Chem"},{"key":"5989_CR37","doi-asserted-by":"publisher","DOI":"10.1016\/j.fm.2018.01.026","author":"MG Cattelan","year":"2018","unstructured":"Cattelan MG, Nishiyama YPO, Gon\u00e7alves TMV, Coelho AR (2018) Combined effects of oregano essential oil and salt on the growth of Escherichia coli in salad dressing. Food Microbiol. https:\/\/doi.org\/10.1016\/j.fm.2018.01.026","journal-title":"Food Microbiol"},{"key":"5989_CR38","doi-asserted-by":"publisher","DOI":"10.5455\/jice.20160331064446","author":"H Sakkas","year":"2016","unstructured":"Sakkas H, Gousia P, Economou V et al (2016) In vitro antimicrobial activity of five essential oils on multidrug resistant Gram-negative clinical isolates. J Intercult Ethnopharmacol. https:\/\/doi.org\/10.5455\/jice.20160331064446","journal-title":"J Intercult Ethnopharmacol"},{"key":"5989_CR39","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/8751718","author":"S Jan","year":"2020","unstructured":"Jan S, Rashid M, Abd-Allah EF, Ahmad P (2020) Biological efficacy of essential oils and plant extracts of cultivated and wild ecotypes of Origanum vulgare L. Biomed Res Int. https:\/\/doi.org\/10.1155\/2020\/8751718","journal-title":"Biomed Res Int"},{"key":"5989_CR40","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiosc.2010.06.010","author":"P Rattanachaikunsopon","year":"2010","unstructured":"Rattanachaikunsopon P, Phumkhachorn P (2010) Assessment of factors influencing antimicrobial activity of carvacrol and cymene against Vibrio cholerae in food. J Biosci Bioeng. https:\/\/doi.org\/10.1016\/j.jbiosc.2010.06.010","journal-title":"J Biosci Bioeng"},{"key":"5989_CR41","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00340-07","author":"SA Burt","year":"2007","unstructured":"Burt SA, Van Der Zee R, Koets AP et al (2007) Carvacrol induces heat shock protein 60 and inhibits synthesis of flagellin in Escherichia coli O157:H7. Appl Environ Microbiol. https:\/\/doi.org\/10.1128\/AEM.00340-07","journal-title":"Appl Environ Microbiol"},{"key":"5989_CR42","unstructured":"Bnyan I, Hasan H, Ewadh M (2014) Antibacterial activity of carvacrol against different types of bacteria. Adv Life Sci Technol"},{"key":"5989_CR43","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2015.11.042","author":"C Valcourt","year":"2016","unstructured":"Valcourt C, Saulnier P, Umerska A et al (2016) Synergistic interactions between doxycycline and terpenic components of essential oils encapsulated within lipid nanocapsules against gram negative bacteria. Int J Pharm. https:\/\/doi.org\/10.1016\/j.ijpharm.2015.11.042","journal-title":"Int J Pharm"},{"key":"5989_CR44","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2672.2001.01428.x","author":"RJW Lambert","year":"2001","unstructured":"Lambert RJW, Skandamis PN, Coote PJ, Nychas GJE (2001) A study of the minimum inhibitory concentration and mode of action of oregano essential oil, thymol and carvacrol. J Appl Microbiol. https:\/\/doi.org\/10.1046\/j.1365-2672.2001.01428.x","journal-title":"J Appl Microbiol"},{"key":"5989_CR45","doi-asserted-by":"publisher","DOI":"10.1111\/jam.14423","author":"MC Lira","year":"2020","unstructured":"Lira MC, Rodrigues JB, Almeida ETC et al (2020) Efficacy of oregano and rosemary essential oils to affect morphology and membrane functions of noncultivable sessile cells of Salmonella Enteritidis 86 in biofilms formed on stainless steel. J Appl Microbiol. https:\/\/doi.org\/10.1111\/jam.14423","journal-title":"J Appl Microbiol"},{"key":"5989_CR46","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00318-08","author":"JL Fern\u00e1ndez","year":"2008","unstructured":"Fern\u00e1ndez JL, Cartelle M, Muriel L et al (2008) DNA fragmentation in microorganisms assessed in situ. Appl Environ Microbiol. https:\/\/doi.org\/10.1128\/AEM.00318-08","journal-title":"Appl Environ Microbiol"},{"key":"5989_CR47","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1146\/annurev.micro.53.1.217","volume":"53","author":"D Dubnau","year":"1999","unstructured":"Dubnau D (1999) DNA uptake in bacteria. Annu Rev Microbiol 53:217","journal-title":"Annu Rev Microbiol"},{"key":"5989_CR48","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0120937","author":"I Cacciatore","year":"2015","unstructured":"Cacciatore I, Di Giulio M, Fornasari E et al (2015) Carvacrol codrugs: a new approach in the antimicrobial plan. PLoS ONE. https:\/\/doi.org\/10.1371\/journal.pone.0120937","journal-title":"PLoS ONE"},{"key":"5989_CR49","doi-asserted-by":"publisher","first-page":"1675","DOI":"10.1002\/ptr.6103","volume":"32","author":"M Sharifi-Rad","year":"2018","unstructured":"Sharifi-Rad M, Varoni EM, Iriti M et al (2018) Carvacrol and human health: a comprehensive review. Phyther Res 32:1675","journal-title":"Phyther Res"},{"key":"5989_CR50","first-page":"704","volume":"27","author":"MB Cleff","year":"2008","unstructured":"Cleff MB, Meinerz AR, Sallis ES et al (2008) Toxicidade pr\u00e9-cl\u00ednica em doses repetidas do \u00f3leo essencial do Origanum vulgare L. (Or\u00e9gano) em ratas Wistar. Lat Am J Pharm 27:704","journal-title":"Lat Am J Pharm"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-020-05989-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11033-020-05989-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-020-05989-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,28]],"date-time":"2022-11-28T02:55:31Z","timestamp":1669604131000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11033-020-05989-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,15]]},"references-count":50,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["5989"],"URL":"https:\/\/doi.org\/10.1007\/s11033-020-05989-0","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,15]]},"assertion":[{"value":"7 July 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 November 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 November 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This research did not involve humans and animal participants, their data, or biological material. The isolates of <i>A. baumannii<\/i> used in this research belong to the culture collection of the Laboratory of Bacteriology and Bioassays, collected during the years of 2014 to 2016 in the School Hospital of the Federal University of Pelotas (UFPel, Pelotas, RS, Brazil. This study was approved by the appropriate institution (UFPel, Pelotas, RS, Brazil) under number 10146.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All authors consented to participate in the research. All authors read and approved the final manuscript and agreed to publish the research data<b>.<\/b>","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}