{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T21:22:19Z","timestamp":1777065739017,"version":"3.51.4"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1007\/s11033-021-06136-z","type":"journal-article","created":{"date-parts":[[2021,1,17]],"date-time":"2021-01-17T16:02:36Z","timestamp":1610899356000},"page":"85-96","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Deciphering the molecular pathways of apoptosis using purified fractions from leaf extract of Basella alba through studying the regulation of apoptosis related genes"],"prefix":"10.1007","volume":"48","author":[{"given":"Md. Shihabul","family":"Islam","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md. Sifat","family":"Rahi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chowdhury Arif","family":"Jahangir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Israt","family":"Jerin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md Mahmudul","family":"Hasan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazi Md Faisal","family":"Hoque","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3146-2772","authenticated-orcid":false,"given":"Md. Abu","family":"Reza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,1,17]]},"reference":[{"issue":"4","key":"6136_CR1","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1038\/bjc.1972.33","volume":"26","author":"JF Kerr","year":"1972","unstructured":"Kerr JF, Wyllie AH, Currie AR (1972) Apoptosis: a basic biological phenomenon with wideranging implications in tissue kinetics. Br J Cancer 26(4):239\u2013257","journal-title":"Br J Cancer"},{"issue":"3","key":"6136_CR2","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1093\/carcin\/21.3.485","volume":"21","author":"SW Lowe","year":"2000","unstructured":"Lowe SW, Lin AW (2000) Apoptosis in cancer. Carcinogenesis 21(3):485\u2013495","journal-title":"Carcinogenesis"},{"key":"6136_CR3","doi-asserted-by":"publisher","first-page":"150845","DOI":"10.1155\/2014\/150845","volume":"2014","author":"M Hassan","year":"2014","unstructured":"Hassan M, Watari H, AbuAlmaaty A, Ohba Y, Sakuragi N (2014) Apoptosis and molecular targeting therapy in cancer. Biomed Res Int 2014:150845","journal-title":"Biomed Res Int"},{"issue":"1","key":"6136_CR4","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1146\/annurev.pharmtox.41.1.367","volume":"41","author":"CJ Norbury","year":"2001","unstructured":"Norbury CJ, Hickson ID (2001) Cellular responses to DNA damage. Annu Rev Pharmacol Toxicol 41(1):367\u2013401","journal-title":"Annu Rev Pharmacol Toxicol"},{"issue":"4","key":"6136_CR5","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1080\/01926230701320337","volume":"35","author":"S Elmore","year":"2007","unstructured":"Elmore S (2007) Apoptosis: a review of programmed cell death. Toxicol Pathol 35(4):495\u2013516","journal-title":"Toxicol Pathol"},{"issue":"12","key":"6136_CR6","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.1038\/sj.cdd.4401724","volume":"12","author":"G Kroemer","year":"2005","unstructured":"Kroemer G, El-Deiry W, Golstein P, Peter M, Vaux D, Vandenabeele P, Zhivotovsky B, Blagosklonny M, Malorni W, Knight R (2005) Classification of cell death: recommendations of the Nomenclature Committee on Cell Death. Cell Death Differ 12(12):1463\u20131467","journal-title":"Cell Death Differ"},{"issue":"2","key":"6136_CR7","first-page":"133","volume":"14","author":"RA Schwartzman","year":"1993","unstructured":"Schwartzman RA, Cidlowski JA (1993) Apoptosis: the biochemistry and molecular biology of programmed cell death. Endocr Rev 14(2):133\u2013151","journal-title":"Endocr Rev"},{"issue":"6805","key":"6136_CR8","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1038\/35037710","volume":"407","author":"MO Hengartner","year":"2000","unstructured":"Hengartner MO (2000) The biochemistry of apoptosis. Nature 407(6805):770\u2013776","journal-title":"Nature"},{"issue":"4","key":"6136_CR9","doi-asserted-by":"publisher","first-page":"a008656","DOI":"10.1101\/cshperspect.a008656","volume":"5","author":"DR McIlwain","year":"2013","unstructured":"McIlwain DR, Berger T, Mak TW (2013) Caspase functions in cell death and disease. Cold Spring Harb Perspect Biol 5(4):a008656","journal-title":"Cold Spring Harb Perspect Biol"},{"issue":"16","key":"6136_CR10","doi-asserted-by":"publisher","first-page":"2861","DOI":"10.1038\/sj.onc.1207523","volume":"23","author":"X Saelens","year":"2004","unstructured":"Saelens X, Festjens N, Walle LV, Van Gurp M, Van Loo G, Vandenabeele P (2004) Toxic proteins released from mitochondria in cell death. Oncogene 23(16):2861\u20132874","journal-title":"Oncogene"},{"key":"6136_CR11","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1146\/annurev-genet-102108-134850","volume":"43","author":"C Wang","year":"2009","unstructured":"Wang C, Youle RJ (2009) The role of mitochondria in apoptosis. Annu Rev Genet 43:95\u2013118","journal-title":"Annu Rev Genet"},{"key":"6136_CR12","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1126\/science.281.5381.1305","volume":"281","author":"A Ashkenazi","year":"1998","unstructured":"Ashkenazi A, Dixit VM (1998) Death receptors: signaling and modulation. Science 281:1305\u20131308","journal-title":"Science"},{"key":"6136_CR13","doi-asserted-by":"crossref","unstructured":"Schneider P, Tschopp J (2000) Apoptosis induced by death receptors. In: Pharmacochemistry library, vol 31. Elsevier, pp 281\u2013286","DOI":"10.1016\/S0165-7208(00)80030-6"},{"issue":"34","key":"6136_CR14","doi-asserted-by":"publisher","first-page":"4798","DOI":"10.1038\/sj.onc.1209608","volume":"25","author":"S Fulda","year":"2006","unstructured":"Fulda S, Debatin K-M (2006) Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene 25(34):4798\u20134811","journal-title":"Oncogene"},{"issue":"12","key":"6136_CR15","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1016\/j.apjtb.2017.10.016","volume":"7","author":"J Iqbal","year":"2017","unstructured":"Iqbal J, Abbasi BA, Mahmood T, Kanwal S, Ali B, Shah SA, Khalil AT (2017) Plant-derived anticancer agents: A green anticancer approach. Asian Pac J Trop Biomed 7(12):1129\u20131150","journal-title":"Asian Pac J Trop Biomed"},{"issue":"2","key":"6136_CR16","first-page":"189","volume":"12","author":"AD Kinghorn","year":"2009","unstructured":"Kinghorn AD, Chin Y-W, Swanson SM (2009) Discovery of natural product anticancer agents from biodiverse organisms. Curr Opin Drug Discovery Dev 12(2):189","journal-title":"Curr Opin Drug Discovery Dev"},{"issue":"11","key":"6136_CR17","doi-asserted-by":"publisher","first-page":"3533","DOI":"10.3390\/ijms19113533","volume":"19","author":"A Lichota","year":"2018","unstructured":"Lichota A, Gwozdzinski K (2018) Anticancer activity of natural compounds from plant and marine environment. Int J Mol Sci 19(11):3533","journal-title":"Int J Mol Sci"},{"issue":"11","key":"6136_CR18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0187925","volume":"12","author":"A Rayan","year":"2017","unstructured":"Rayan A, Raiyn J, Falah M (2017) Nature is the best source of anticancer drugs: Indexing natural products for their anticancer bioactivity. PLoS One 12(11):e0187925","journal-title":"PLoS One"},{"issue":"2","key":"6136_CR19","first-page":"110","volume":"4","author":"R Adhikari","year":"2012","unstructured":"Adhikari R, Kumar HN, Shruthi S (2012) A review on medicinal importance of Basella alba L. Int J Pharm Sci Drug Res 4(2):110\u2013114","journal-title":"Int J Pharm Sci Drug Res"},{"issue":"12","key":"6136_CR20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0167536","volume":"11","author":"AK Alam","year":"2016","unstructured":"Alam AK, Hossain AS, Khan MA, Kabir SR, Reza MA, Rahman MM, Islam MS, Rahman MAA, Rashid M, Sadik MG (2016) The antioxidative fraction of white mulberry induces apoptosis through regulation of p53 and NF\u03baB in EAC cells. PLoS One 11(12):e0167536","journal-title":"PLoS One"},{"issue":"14","key":"6136_CR21","doi-asserted-by":"publisher","first-page":"1288","DOI":"10.1016\/j.phymed.2013.06.010","volume":"20","author":"SR Kabir","year":"2013","unstructured":"Kabir SR, Nabi MM, Haque A, Zaman RU, Mahmud ZH, Reza MA (2013) Pea lectin inhibits growth of Ehrlich ascites carcinoma cells by inducing apoptosis and G2\/M cell cycle arrest in vivo in mice. Phytomedicine 20(14):1288\u20131296","journal-title":"Phytomedicine"},{"issue":"5","key":"6136_CR22","doi-asserted-by":"publisher","first-page":"2616","DOI":"10.1007\/s12010-014-1449-2","volume":"175","author":"SR Kabir","year":"2015","unstructured":"Kabir SR, Nabi MM, Nurujjaman M, Reza MA, Alam AK, Zaman RU, Khalid-Bin-Ferdaus KM, Amin R, Khan MMH, Hossain MA (2015) Momordica charantia seed lectin: toxicity, bacterial agglutination and antitumor properties. Appl Biochem Biotechnol 175(5):2616\u20132628","journal-title":"Appl Biochem Biotechnol"},{"issue":"02","key":"6136_CR23","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1055\/s-2006-959427","volume":"60","author":"P Sur","year":"1994","unstructured":"Sur P, Ganguly DK (1994) Tea plant root extract (TRE) as an antineoplastic agent. Planta Med 60(02):106\u2013109","journal-title":"Planta Med"},{"key":"6136_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2018\/1537896","volume":"2018","author":"M Islam","year":"2018","unstructured":"Islam M, Rahi M, Jahangir CA, Rahman MH, Jerin I, Amin R, Hoque KM, Reza MA (2018) In vivo anticancer activity of basella alba leaf and seed extracts against Ehrlich\u2019s Ascites Carcinoma (EAC) cell line. Evid Based Complement Alternat Med 2018:1\u201311","journal-title":"Evid Based Complement Alternat Med"},{"issue":"4","key":"6136_CR25","doi-asserted-by":"publisher","first-page":"1202","DOI":"10.1007\/s10753-014-9847-8","volume":"37","author":"L Pinhu","year":"2014","unstructured":"Pinhu L, Qin Y, Xiong B, You Y, Li J, Sooranna SR (2014) Overexpression of Fas and FasL is associated with infectious complications and severity of experimental severe acute pancreatitis by promoting apoptosis of lymphocytes. Inflammation 37(4):1202\u20131212","journal-title":"Inflammation"},{"issue":"3","key":"6136_CR26","first-page":"353","volume":"27","author":"K Fukumoto","year":"2011","unstructured":"Fukumoto K, Naito Y, Takagi T, Yamada S, Horie R, Inoue K, Harusato A, Hirata I, Omatsu T, Mizushima K (2011) Role of tumor necrosis factor-\u03b1 in the pathogenesis of indomethacin-induced small intestinal injury in mice. Int J Mol Med 27(3):353\u2013359","journal-title":"Int J Mol Med"},{"issue":"1","key":"6136_CR27","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1095\/biolreprod61.1.231","volume":"61","author":"GE Exley","year":"1999","unstructured":"Exley GE, Tang C, McElhinny AS, Warner CM (1999) Expression of caspase and BCL-2 apoptotic family members in mouse preimplantation embryos. Biol Reprod 61(1):231\u2013239","journal-title":"Biol Reprod"},{"issue":"3","key":"6136_CR28","doi-asserted-by":"publisher","first-page":"271","DOI":"10.5487\/TR.2019.35.3.271","volume":"35","author":"MM Hasan","year":"2019","unstructured":"Hasan MM, Islam MS, Hoque KMF, Haque A, Reza MA (2019) Effect of Citrus macroptera fruit pulp juice on alteration of caspase pathway rendering anti-proliferative activity against Ehrlich\u2019s ascites carcinoma in mice. Toxicol Res 35(3):271\u2013277","journal-title":"Toxicol Res"},{"issue":"1","key":"6136_CR29","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1186\/s12906-016-1130-0","volume":"16","author":"MA Al-Mamun","year":"2016","unstructured":"Al-Mamun MA, Husna J, Khatun M, Hasan R, Kamruzzaman M, Hoque K, Reza MA, Ferdousi Z (2016) Assessment of antioxidant, anticancer and antimicrobial activity of two vegetable species of Amaranthus in Bangladesh. BMC Complement Altern Med 16(1):157","journal-title":"BMC Complement Altern Med"},{"key":"6136_CR30","doi-asserted-by":"publisher","first-page":"625961","DOI":"10.1155\/2014\/625961","volume":"2014","author":"V Nemudzivhadi","year":"2014","unstructured":"Nemudzivhadi V, Masoko P (2014) In vitro assessment of cytotoxicity, antioxidant, and anti-inflammatory activities of Ricinus communis (Euphorbiaceae) leaf extracts. Evid Based Complement Alternat Med 2014:625961","journal-title":"Evid Based Complement Alternat Med"},{"issue":"1","key":"6136_CR31","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1007\/s10616-018-0274-9","volume":"71","author":"T Kowalczyk","year":"2019","unstructured":"Kowalczyk T, Sitarek P, Ska\u0142a E, Toma M, Wielanek M, Pytel D, Wieczfi\u0144ska J, Szemraj J, \u015aliwi\u0144ski T (2019) Induction of apoptosis by in vitro and in vivo plant extracts derived from Menyanthes trifoliata L. in human cancer cells. Cytotechnology 71(1):165\u2013180","journal-title":"Cytotechnology"},{"issue":"2","key":"6136_CR32","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1038\/bjc.2013.325","volume":"109","author":"S Martin","year":"2013","unstructured":"Martin S, Lamb H, Brady C, Lefkove B, Bonner M, Thompson P, Lovat P, Arbiser J, Hawkins A, Redfern C (2013) Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP78. Br J Cancer 109(2):433\u2013443","journal-title":"Br J Cancer"},{"issue":"Suppl 1","key":"6136_CR33","first-page":"421","volume":"4","author":"E Safarzadeh","year":"2014","unstructured":"Safarzadeh E, Shotorbani SS, Baradaran B (2014) Herbal medicine as inducers of apoptosis in cancer treatment. Adv Pharm Bull 4(Suppl 1):421","journal-title":"Adv Pharm Bull"},{"issue":"3","key":"6136_CR34","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1038\/nrc1560","volume":"5","author":"JM Brown","year":"2005","unstructured":"Brown JM, Attardi LD (2005) The role of apoptosis in cancer development and treatment response. Nat Rev Cancer 5(3):231\u2013237","journal-title":"Nat Rev Cancer"},{"issue":"4","key":"6136_CR35","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1007\/s10616-015-9897-2","volume":"68","author":"M Kumar","year":"2016","unstructured":"Kumar M, Kaur V, Kumar S, Kaur S (2016) Phytoconstituents as apoptosis inducing agents: strategy to combat cancer. Cytotechnology 68(4):531\u2013563","journal-title":"Cytotechnology"},{"key":"6136_CR36","doi-asserted-by":"publisher","first-page":"474953","DOI":"10.1155\/2014\/474953","volume":"2014","author":"S Pajaniradje","year":"2014","unstructured":"Pajaniradje S, Mohankumar K, Pamidimukkala R, Subramanian S, Rajagopalan R (2014) Antiproliferative and apoptotic effects of Sesbania grandiflora leaves in human cancer cells. Biomed Res Int 2014:474953","journal-title":"Biomed Res Int"},{"key":"6136_CR37","doi-asserted-by":"publisher","first-page":"e13342","DOI":"10.1111\/jfbc.13342","volume":"44","author":"MS Rahi","year":"2020","unstructured":"Rahi MS, Islam MS, Jerin I, Jahangir CA, Hasan MM, Hoque KMF, Reza MA (2020) Differential expression of Bax-Bcl-2 and PARP-1 confirms apoptosis of EAC cells in Swiss albino mice by Morus laevigata. J Food Biochem 44:e13342","journal-title":"J Food Biochem"},{"issue":"2","key":"6136_CR38","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/S0092-8674(00)80197-X","volume":"89","author":"X Liu","year":"1997","unstructured":"Liu X, Zou H, Slaughter C, Wang X (1997) DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89(2):175\u2013184","journal-title":"Cell"},{"issue":"1","key":"6136_CR39","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1475-2867-10-14","volume":"10","author":"H Abdullah","year":"2010","unstructured":"Abdullah H, Pihie AHL, Hohmann J, Moln\u00e1r J (2010) A natural compound from Hydnophytum formicarium induces apoptosis of MCF-7 cells via up-regulation of Bax. Cancer Cell Int 10(1):1\u20136","journal-title":"Cancer Cell Int"},{"issue":"1","key":"6136_CR40","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1038\/sj.cdd.4401161","volume":"10","author":"S Nagata","year":"2003","unstructured":"Nagata S, Nagase H, Kawane K, Mukae N, Fukuyama H (2003) Degradation of chromosomal DNA during apoptosis. Cell Death Differ 10(1):108\u2013116","journal-title":"Cell Death Differ"},{"issue":"7","key":"6136_CR41","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1007\/s10495-012-0715-4","volume":"17","author":"S Kar","year":"2012","unstructured":"Kar S, Palit S, Ball WB, Das PK (2012) Carnosic acid modulates Akt\/IKK\/NF-\u03baB signaling by PP2A and induces intrinsic and extrinsic pathway mediated apoptosis in human prostate carcinoma PC-3 cells. Apoptosis 17(7):735\u2013747","journal-title":"Apoptosis"},{"issue":"4","key":"6136_CR42","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1007\/s10495-009-0436-5","volume":"15","author":"S Raychaudhuri","year":"2010","unstructured":"Raychaudhuri S, Skommer J, Henty K, Birch N, Brittain T (2010) Neuroglobin protects nerve cells from apoptosis by inhibiting the intrinsic pathway of cell death. Apoptosis 15(4):401\u2013411","journal-title":"Apoptosis"},{"issue":"6","key":"6136_CR43","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1080\/02841860902974175","volume":"48","author":"C Burz","year":"2009","unstructured":"Burz C, Berindan-Neagoe I, Balacescu O, Irimie A (2009) Apoptosis in cancer: key molecular signaling pathways and therapy targets. Acta Oncol 48(6):811\u2013821","journal-title":"Acta Oncol"},{"issue":"4","key":"6136_CR44","doi-asserted-by":"publisher","first-page":"603","DOI":"10.18632\/aging.100934","volume":"8","author":"G Pistritto","year":"2016","unstructured":"Pistritto G, Trisciuoglio D, Ceci C, Garufi A, D\u2019Orazi G (2016) Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies. Aging (Albany NY) 8(4):603","journal-title":"Aging (Albany NY)"},{"issue":"9","key":"6136_CR45","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0043632","volume":"7","author":"M Hegde","year":"2012","unstructured":"Hegde M, Karki SS, Thomas E, Kumar S, Panjamurthy K, Ranganatha SR, Rangappa KS, Choudhary B, Raghavan SC (2012) Novel levamisole derivative induces extrinsic pathway of apoptosis in cancer cells and inhibits tumor progression in mice. PLoS One 7(9):e43632","journal-title":"PLoS One"},{"issue":"4","key":"6136_CR46","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1016\/S0092-8674(01)00237-9","volume":"104","author":"RM Locksley","year":"2001","unstructured":"Locksley RM, Killeen N, Lenardo MJ (2001) The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104(4):487\u2013501","journal-title":"Cell"},{"issue":"2","key":"6136_CR47","doi-asserted-by":"publisher","first-page":"448","DOI":"10.3390\/ijms19020448","volume":"19","author":"CM Pfeffer","year":"2018","unstructured":"Pfeffer CM, Singh AT (2018) Apoptosis: a target for anticancer therapy. Int J Mol Sci 19(2):448","journal-title":"Int J Mol Sci"},{"issue":"2","key":"6136_CR48","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.3892\/or.2016.5303","volume":"37","author":"B Wang","year":"2017","unstructured":"Wang B, Zhao X-H (2017) Apigenin induces both intrinsic and extrinsic pathways of apoptosis in human colon carcinoma HCT-116 cells. Oncol Rep 37(2):1132\u20131140","journal-title":"Oncol Rep"},{"key":"6136_CR49","doi-asserted-by":"publisher","first-page":"254960","DOI":"10.1155\/2012\/254960","volume":"2012","author":"J-S Yang","year":"2012","unstructured":"Yang J-S, Wu C-C, Kuo C-L, Lan Y-H, Yeh C-C, Yu C-C, Lien J-C, Hsu Y-M, Kuo W-W, Wood WG (2012) Solanum lyratum extracts induce extrinsic and intrinsic pathways of apoptosis in WEHI-3 murine leukemia cells and inhibit allograft tumor. Evid Based Complement Alternat Med 2012:254960","journal-title":"Evid Based Complement Alternat Med"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-021-06136-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11033-021-06136-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-021-06136-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,28]],"date-time":"2023-01-28T09:11:27Z","timestamp":1674897087000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11033-021-06136-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["6136"],"URL":"https:\/\/doi.org\/10.1007\/s11033-021-06136-z","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"31 July 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 January 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 January 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All the authors declared that there are no known conflicts of interest related to this publication and there has been no significant financial support for this research work that could have influenced its outcome.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The experimental portions using the animal model has been approved by the authority of Institutional Animal, Medical Ethics, Bio-safety, and Bio-security Committee (IAMEBBC), of Institute of Biological Sciences, University of Rajshahi-6205, Bangladesh. (License no. 31\/320 IAMEBBC\/I BSc).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The manuscript has been submitted into the bioRxiv preprint platform at December 3, 2018. The copyright holder for this preprint is the author\/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission. DOI: .","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Preprint information"}}]}}