{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:31:08Z","timestamp":1790627468449,"version":"4.1.0"},"reference-count":86,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T00:00:00Z","timestamp":1637712000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T00:00:00Z","timestamp":1637712000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1007\/s11033-021-06967-w","type":"journal-article","created":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T05:02:37Z","timestamp":1637730157000},"page":"2335-2344","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Structural and functional changes in the kidney caused by adverse fetal and neonatal environments"],"prefix":"10.1007","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9350-5339","authenticated-orcid":false,"given":"Midori","family":"Awazu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,11,24]]},"reference":[{"key":"6967_CR1","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1016\/s0899-9007(97)00193-7","volume":"13","author":"DJ Barker","year":"1997","unstructured":"Barker DJ (1997) Maternal nutrition, fetal nutrition, and disease in later life. Nutrition 13:807\u2013813. https:\/\/doi.org\/10.1016\/s0899-9007(97)00193-7","journal-title":"Nutrition"},{"key":"6967_CR2","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1159\/000044987","volume":"79","author":"N Zidar","year":"1998","unstructured":"Zidar N, Cavi\u0107 MA, Kenda RB, Koselj M, Ferluga D (1998) Effect of intrauterine growth retardation on the clinical course and prognosis of IgA glomerulonephritis in children. Nephron 79:28\u201332. https:\/\/doi.org\/10.1159\/000044987","journal-title":"Nephron"},{"key":"6967_CR3","doi-asserted-by":"publisher","first-page":"1320","DOI":"10.1046\/j.1523-1755.1998.00121.x","volume":"54","author":"N Zidar","year":"1998","unstructured":"Zidar N, Avgustin Cavi\u0107 M, Kenda RB, Ferluga D (1998) Unfavorable course of minimal change nephrotic syndrome in children with intrauterine growth retardation. Kidney Int 54:1320\u20131323. https:\/\/doi.org\/10.1046\/j.1523-1755.1998.00121.x","journal-title":"Kidney Int"},{"key":"6967_CR4","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.2337\/diab.1444.1412.1405","volume":"44","author":"P Rossing","year":"1995","unstructured":"Rossing P, Tarnow L, Nielsen FS, Hansen BV, Brenner BM, Parving HH (1995) Low birth weight. A risk factor for development of diabetic nephropathy? Diabetes 44:1405\u20131407. https:\/\/doi.org\/10.2337\/diab.1444.1412.1405","journal-title":"Diabetes"},{"key":"6967_CR5","first-page":"875","volume":"9","author":"RC Duncan","year":"1994","unstructured":"Duncan RC, Bass PS, Garrett PJ, Dathan JR (1994) Weight at birth and other factors influencing progression of idiopathic membranous nephropathy. Nephrol Dial Transplant 9:875","journal-title":"Nephrol Dial Transplant"},{"key":"6967_CR6","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1080\/080352501750258676","volume":"90","author":"M Hellstr\u00f6m","year":"2001","unstructured":"Hellstr\u00f6m M, Hessel H, Jacobsson B, Jodal U, Niklasson A, Wennerstr\u00f6m M, Hellstr\u00f6m A (2001) Association between urinary tract infection, renal damage and birth size. Acta Paediatr 90:628\u2013631","journal-title":"Acta Paediatr"},{"key":"6967_CR7","doi-asserted-by":"publisher","first-page":"2113","DOI":"10.1046\/j.1523-1755.2003.00018.x","volume":"63","author":"M Hughson","year":"2003","unstructured":"Hughson M, Farris AB 3rd, Douglas-Denton R, Hoy WE, Bertram JF (2003) Glomerular number and size in autopsy kidneys: the relationship to birth weight. Kidney Int 63:2113\u20132122. https:\/\/doi.org\/10.1046\/j.1523-1755.2003.00018.x","journal-title":"Kidney Int"},{"key":"6967_CR8","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1093\/ndt\/gft1480","volume":"29","author":"MD Hughson","year":"2014","unstructured":"Hughson MD, Puelles VG, Hoy WE, Douglas-Denton RN, Mott SA, Bertram JF (2014) Hypertension, glomerular hypertrophy and nephrosclerosis: the effect of race. Nephrol Dial Transplant 29:1399\u20131409. https:\/\/doi.org\/10.1093\/ndt\/gft1480","journal-title":"Nephrol Dial Transplant"},{"key":"6967_CR9","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1038\/ki.2011.459","volume":"81","author":"B Orskov","year":"2012","unstructured":"Orskov B, Christensen KB, Feldt-Rasmussen B, Strandgaard S (2012) Low birth weight is associated with earlier onset of end-stage renal disease in Danish patients with autosomal dominant polycystic kidney disease. Kidney Int 81:919\u2013924. https:\/\/doi.org\/10.1038\/ki.2011.459","journal-title":"Kidney Int"},{"key":"6967_CR10","doi-asserted-by":"publisher","first-page":"4136","DOI":"10.1093\/ndt\/gfr252","volume":"26","author":"T Rajan","year":"2011","unstructured":"Rajan T, Barbour SJ, White CT, Levin A (2011) Low birth weight and nephron mass and their role in the progression of chronic kidney disease: a case report on identical twins with Alport disease. Nephrol Dial Transplant 26:4136\u20134139. https:\/\/doi.org\/10.1093\/ndt\/gfr252","journal-title":"Nephrol Dial Transplant"},{"key":"6967_CR11","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1007\/s00467-012-2107-y","volume":"27","author":"BF Melo","year":"2012","unstructured":"Melo BF, Aguiar MB, Bouzada MC, Aguiar RL, Pereira AK, Paix\u00e3o GM, Linhares MC, Valerio FC, Sim\u00f5es ESAC, Oliveira EA (2012) Early risk factors for neonatal mortality in CAKUT: analysis of 524 affected newborns. Pediatr Nephrol 27:965\u2013972. https:\/\/doi.org\/10.1007\/s00467-012-2107-y","journal-title":"Pediatr Nephrol"},{"key":"6967_CR12","doi-asserted-by":"publisher","first-page":"1974","DOI":"10.1038\/sj.ki.5001966","volume":"70","author":"C Plank","year":"2006","unstructured":"Plank C, Ostreicher I, Hartner A, Marek I, Struwe FG, Amann K, Hilgers KF, Rascher W, D\u00f6tsch J (2006) Intrauterine growth retardation aggravates the course of acute mesangioproliferative glomerulonephritis in the rat. Kidney Int 70:1974\u20131982. https:\/\/doi.org\/10.1038\/sj.ki.5001966","journal-title":"Kidney Int"},{"key":"6967_CR13","doi-asserted-by":"publisher","first-page":"F420","DOI":"10.1152\/ajprenal.00045.2011","volume":"301","author":"NB Ojeda","year":"2011","unstructured":"Ojeda NB (2011) Low birth weight increases susceptibility to renal injury in a rat model of mild ischemia-reperfusion. Am J Physiol Renal Physiol 301:F420-426. https:\/\/doi.org\/10.1152\/ajprenal.00045.2011","journal-title":"Am J Physiol Renal Physiol"},{"key":"6967_CR14","doi-asserted-by":"publisher","first-page":"e0221686","DOI":"10.1371\/journal.pone.0221686","volume":"14","author":"M Awazu","year":"2019","unstructured":"Awazu M, Abe T, Hashiguchi A, Hida M (2019) Maternal undernutrition aggravates renal tubular necrosis and interstitial fibrosis after unilateral ureteral obstruction in male rat offspring. PLoS ONE 14:e0221686. https:\/\/doi.org\/10.1371\/journal.pone.0221686","journal-title":"PLoS ONE"},{"key":"6967_CR15","doi-asserted-by":"publisher","first-page":"e0213404","DOI":"10.1371\/journal.pone.0213404","volume":"14","author":"AD Newsome","year":"2019","unstructured":"Newsome AD, Davis GK, Adah ON, Ojeda NB, Alexander BT (2019) Renal injury after uninephrectomy in male and female intrauterine growth-restricted aged rats. PLoS ONE 14:e0213404. https:\/\/doi.org\/10.1371\/journal.pone.0213404","journal-title":"PLoS ONE"},{"key":"6967_CR16","doi-asserted-by":"publisher","first-page":"F1093","DOI":"10.1152\/ajprenal.00487.02020","volume":"320","author":"MB Cobb","year":"2021","unstructured":"Cobb MB, Wu W, Attipoe EM, Johnson AC, Garrett MR (2021) Nephron-deficient HSRA rats exhibit renal injury with age but have limited renal damage from streptozotocin-induced hyperglycemia. Am J Physiol Renal Physiol 320:F1093\u2013F1105. https:\/\/doi.org\/10.1152\/ajprenal.00487.02020","journal-title":"Am J Physiol Renal Physiol"},{"key":"6967_CR17","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1053\/j.ajkd.2008.1012.1042","volume":"54","author":"SL White","year":"2009","unstructured":"White SL, Perkovic V, Cass A, Chang CL, Poulter NR, Spector T, Haysom L, Craig JC, Salmi IA, Chadban SJ, Huxley RR (2009) Is low birth weight an antecedent of CKD in later life? A systematic review of observational studies. Am J Kidney Dis 54:248\u2013261. https:\/\/doi.org\/10.1053\/j.ajkd.2008.1012.1042","journal-title":"Am J Kidney Dis"},{"key":"6967_CR18","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1681\/ASN.2007020252","volume":"19","author":"BE Vikse","year":"2008","unstructured":"Vikse BE, Irgens LM, Leivestad T, Hallan S, Iversen BM (2008) Low birth weight increases risk for end-stage renal disease. J Am Soc Nephrol 19:151\u2013157. https:\/\/doi.org\/10.1681\/ASN.2007020252","journal-title":"J Am Soc Nephrol"},{"key":"6967_CR19","doi-asserted-by":"publisher","first-page":"71","DOI":"10.2215\/CJN.01700408","volume":"4","author":"JB Hodgin","year":"2009","unstructured":"Hodgin JB, Rasoulpour M, Markowitz GS, D\u2019Agati VD (2009) Very low birth weight is a risk factor for secondary focal segmental glomerulosclerosis. Clin J Am Soc Nephrol 4:71\u201376. https:\/\/doi.org\/10.2215\/CJN.01700408","journal-title":"Clin J Am Soc Nephrol"},{"key":"6967_CR20","doi-asserted-by":"publisher","first-page":"2105","DOI":"10.1681\/ASN.2013060582","volume":"25","author":"CW Hsu","year":"2014","unstructured":"Hsu CW, Yamamoto KT, Henry RK, De Roos AJ, Flynn JT (2014) Prenatal risk factors for childhood CKD. J Am Soc Nephrol 25:2105\u20132111. https:\/\/doi.org\/10.1681\/ASN.2013060582","journal-title":"J Am Soc Nephrol"},{"key":"6967_CR21","doi-asserted-by":"publisher","first-page":"1523","DOI":"10.1093\/ndt\/gfv1458","volume":"31","author":"T Schachtner","year":"2016","unstructured":"Schachtner T, Reinke P (2016) Estimated nephron number of the remaining donor kidney: impact on living kidney donor outcomes. Nephrol Dial Transplant 31:1523\u20131530. https:\/\/doi.org\/10.1093\/ndt\/gfv1458","journal-title":"Nephrol Dial Transplant"},{"key":"6967_CR22","first-page":"021","volume":"16","author":"Y Wu","year":"2021","unstructured":"Wu Y, Wang H, Pei J, Jiang X, Tang J (2021) Acute kidney injury in premature and low birth weight neonates: a systematic review and meta-analysis. Pediatr Nephrol 16:021\u201305251","journal-title":"Pediatr Nephrol"},{"key":"6967_CR23","doi-asserted-by":"publisher","first-page":"2036","DOI":"10.2215\/CJN.05190514","volume":"9","author":"JB Carmody","year":"2014","unstructured":"Carmody JB, Swanson JR, Rhone ET, Charlton JR (2014) Recognition and reporting of AKI in very low birth weight infants. Clin J Am Soc Nephrol 9:2036\u20132043. https:\/\/doi.org\/10.2215\/CJN.05190514","journal-title":"Clin J Am Soc Nephrol"},{"key":"6967_CR24","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1046\/j.1523-1755.2002.00264.x","volume":"61","author":"SJ Welham","year":"2002","unstructured":"Welham SJ, Wade A, Woolf AS (2002) Protein restriction in pregnancy is associated with increased apoptosis of mesenchymal cells at the start of rat metanephrogenesis. Kidney Int 61:1231\u20131242","journal-title":"Kidney Int"},{"key":"6967_CR25","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1038\/pr.2015.24","volume":"77","author":"M Awazu","year":"2015","unstructured":"Awazu M, Hida M (2015) Maternal nutrient restriction inhibits ureteric bud branching but does not affect the duration of nephrogenesis in rats. Pediatr Res 77:633\u2013639. https:\/\/doi.org\/10.1038\/pr.2015.24","journal-title":"Pediatr Res"},{"key":"6967_CR26","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.celrep.2014.02.033","volume":"7","author":"C Cebrian","year":"2014","unstructured":"Cebrian C, Asai N, D\u2019Agati V, Costantini F (2014) The number of fetal nephron progenitor cells limits ureteric branching and adult nephron endowment. Cell Rep 7:127\u2013137. https:\/\/doi.org\/10.1016\/j.celrep.2014.02.033","journal-title":"Cell Rep"},{"key":"6967_CR27","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1038\/pr.2017.53","volume":"82","author":"C Barnett","year":"2017","unstructured":"Barnett C, Nnoli O, Abdulmahdi W, Nesi L, Shen M, Zullo JA, Payne DL, Azar T, Dwivedi P, Syed K, Gromis J, Lipphardt M, Jules E, Maranda EL, Patel A, Rabadi MM, Ratliff BB (2017) Low birth weight is associated with impaired murine kidney development and function. Pediatr Res 82:340\u2013348. https:\/\/doi.org\/10.1038\/pr.2017.53","journal-title":"Pediatr Res"},{"key":"6967_CR28","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.devcel.2015.09.023","volume":"35","author":"MH Little","year":"2015","unstructured":"Little MH (2015) The life cycle of the nephron progenitor. Dev Cell 35:5\u20136. https:\/\/doi.org\/10.1016\/j.devcel.2015.09.023","journal-title":"Dev Cell"},{"key":"6967_CR29","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1681\/ASN.2020101459","volume":"32","author":"MP Schuh","year":"2021","unstructured":"Schuh MP, Alkhudairy L, Potter A, Potter SS, Chetal K, Thakkar K, Salomonis N, Kopan R (2021) The rhesus macaque serves as a model for human lateral branch nephrogenesis. J Am Soc Nephrol 32:1097\u20131112. https:\/\/doi.org\/10.1681\/ASN.2020101459","journal-title":"J Am Soc Nephrol"},{"key":"6967_CR30","doi-asserted-by":"publisher","first-page":"e0230289","DOI":"10.1371\/journal.pone.0230289","volume":"15","author":"M Awazu","year":"2020","unstructured":"Awazu M, Hida M (2020) Folic acid supplementation alleviates reduced ureteric branching, nephrogenesis, and global DNA methylation induced by maternal nutrient restriction in rat embryonic kidney. PLoS ONE 15:e0230289. https:\/\/doi.org\/10.1371\/journal.pone.0230289","journal-title":"PLoS ONE"},{"key":"6967_CR31","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1681\/ASN.2018070687","volume":"30","author":"SY Li","year":"2019","unstructured":"Li SY, Park J, Guan Y, Chung K, Shrestha R, Palmer MB, Susztak K (2019) DNMT1 in Six2 progenitor cells is essential for transposable element silencing and kidney development. J Am Soc Nephrol 30:594\u2013609. https:\/\/doi.org\/10.1681\/ASN.2018070687","journal-title":"J Am Soc Nephrol"},{"key":"6967_CR32","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1681\/ASN.2018070736","volume":"30","author":"N Wanner","year":"2019","unstructured":"Wanner N, Vornweg J, Combes A, Wilson S, Plappert J, Rafflenbeul G, Puelles VG, Rahman RU, Liwinski T, Lindner S, Grahammer F, Kretz O, Wlodek ME, Romano T, Moritz KM, Boerries M, Busch H, Bonn S, Little MH, Bechtel-Walz W, Huber TB (2019) DNA methyltransferase 1 controls nephron progenitor cell renewal and differentiation. J Am Soc Nephrol 30:63\u201378. https:\/\/doi.org\/10.1681\/ASN.2018070736","journal-title":"J Am Soc Nephrol"},{"key":"6967_CR33","doi-asserted-by":"publisher","first-page":"1898","DOI":"10.1681\/ASN.2020091321","volume":"32","author":"Y Makayes","year":"2021","unstructured":"Makayes Y, Resnick E, Hinden L, Aizenshtein E, Shlomi T, Kopan R, Nechama M, Volovelsky O (2021) Increasing mTORC1 pathway activity or methionine supplementation during pregnancy reverses the negative effect of maternal malnutrition on the developing kidney. J Am Soc Nephrol 32:1898\u20131912. https:\/\/doi.org\/10.1681\/ASN.2020091321","journal-title":"J Am Soc Nephrol"},{"key":"6967_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3339\/jkspn.2017.21.1.1","volume":"21","author":"M Awazu","year":"2017","unstructured":"Awazu M (2017) Mitogen-activated protein kinases in the development of normal and diseased kidneys. Child Kidney Dis 21:1\u20137. https:\/\/doi.org\/10.3339\/jkspn.2017.21.1.1","journal-title":"Child Kidney Dis"},{"key":"6967_CR35","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1006\/excr.1999.4424","volume":"248","author":"T Araki","year":"1999","unstructured":"Araki T, Saruta T, Okano H, Miura M (1999) Caspase activity is required for nephrogenesis in the developing mouse metanephros. Exp Cell Res 248:423\u2013429","journal-title":"Exp Cell Res"},{"key":"6967_CR36","doi-asserted-by":"publisher","unstructured":"Awazu M, Yamaguchi Y, Nagata M, Miura M, Hida M (2021) Caspase-3 regulates ureteric branching in mice via cell migration. Biochem Biophys Res Commun 559:28\u201334 https:\/\/doi.org\/10.1016\/j.bbrc.2021.04.081","DOI":"10.1016\/j.bbrc.2021.04.081"},{"key":"6967_CR37","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/s10024-003-3029-2","volume":"7","author":"MM Rodr\u00edguez","year":"2004","unstructured":"Rodr\u00edguez MM, G\u00f3mez AH, Abitbol CL, Chandar JJ, Duara S, Zilleruelo GE (2004) Histomorphometric analysis of postnatal glomerulogenesis in extremely preterm infants. Pediatr Dev Pathol 7:17\u201325. https:\/\/doi.org\/10.1007\/s10024-003-3029-2","journal-title":"Pediatr Dev Pathol"},{"key":"6967_CR38","doi-asserted-by":"publisher","unstructured":"Chevalier RL (2020) Bioenergetic evolution explains prevalence of low nephron number at birth: risk factor for CKD. Kidney 360 (1):863\u2013879 https:\/\/doi.org\/10.34067\/KID.0002012020","DOI":"10.34067\/KID.0002012020"},{"key":"6967_CR39","doi-asserted-by":"publisher","first-page":"F1668","DOI":"10.1152\/ajprenal.00163.2009","volume":"297","author":"L Gubhaju","year":"2009","unstructured":"Gubhaju L, Sutherland MR, Yoder BA, Zulli A, Bertram JF, Black MJ (2009) Is nephrogenesis affected by preterm birth? Studies in a non-human primate model. Am J Physiol Renal Physiol 297:F1668-1677. https:\/\/doi.org\/10.1152\/ajprenal.00163.2009","journal-title":"Am J Physiol Renal Physiol"},{"key":"6967_CR40","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1111\/j.1651-2227.2008.00904.x","volume":"97","author":"M Norman","year":"2008","unstructured":"Norman M (2008) Low birth weight and the developing vascular tree: a systematic review. Acta Paediatr 97:1165\u20131172. https:\/\/doi.org\/10.1111\/j.1651-2227.2008.00904.x","journal-title":"Acta Paediatr"},{"key":"6967_CR41","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1007\/s00467-017-3654-z","volume":"32","author":"N Asada","year":"2017","unstructured":"Asada N, Tsukahara T, Furuhata M, Matsuoka D, Noda S, Naganuma K, Hashiguchi A, Awazu M (2017) Polycythemia, capillary rarefaction, and focal glomerulosclerosis in two adolescents born extremely low birth weight and premature. Pediatr Nephrol 32:1275\u20131278. https:\/\/doi.org\/10.1007\/s00467-017-3654-z","journal-title":"Pediatr Nephrol"},{"key":"6967_CR42","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1681\/ASN.2014010060","volume":"26","author":"H Dimke","year":"2015","unstructured":"Dimke H, Sparks MA, Thomson BR, Frische S, Coffman TM, Quaggin SE (2015) Tubulovascular cross-talk by vascular endothelial growth factor a maintains peritubular microvasculature in kidney. J Am Soc Nephrol 26:1027\u20131038. https:\/\/doi.org\/10.1681\/ASN.2014010060","journal-title":"J Am Soc Nephrol"},{"key":"6967_CR43","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1113\/jphysiol.2011.220186","volume":"590","author":"LJ Lloyd","year":"2012","unstructured":"Lloyd LJ, Foster T, Rhodes P, Rhind SM, Gardner DS (2012) Protein-energy malnutrition during early gestation in sheep blunts fetal renal vascular and nephron development and compromises adult renal function. J Physiol 590:377\u2013393. https:\/\/doi.org\/10.1113\/jphysiol.2011.220186","journal-title":"J Physiol"},{"key":"6967_CR44","doi-asserted-by":"publisher","first-page":"1988","DOI":"10.1097\/HJH.0000000000001028","volume":"34","author":"MR Sutherland","year":"2016","unstructured":"Sutherland MR, Ryan D, Dahl MJ, Albertine KH, Black MJ (2016) Effects of preterm birth and ventilation on glomerular capillary growth in the neonatal lamb kidney. J Hypertens 34:1988\u20131997. https:\/\/doi.org\/10.1097\/HJH.0000000000001028","journal-title":"J Hypertens"},{"key":"6967_CR45","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1159\/000353898","volume":"38","author":"Y Ikezumi","year":"2013","unstructured":"Ikezumi Y, Suzuki T, Karasawa T, Yamada T, Hasegawa H, Nishimura H, Uchiyama M (2013) Low birthweight and premature birth are risk factors for podocytopenia and focal segmental glomerulosclerosis [Research Support, Non-U.S. Gov\u2019t]. Am J Nephrol 38:149\u2013157. https:\/\/doi.org\/10.1159\/000353898","journal-title":"Am J Nephrol"},{"key":"6967_CR46","doi-asserted-by":"publisher","first-page":"20650","DOI":"10.1038\/s41598-021-00130-y","volume":"11","author":"F Ding","year":"2021","unstructured":"Ding F, Gao Q, Tian X, Mo J, Zheng J (2021) Increasing urinary podocyte mRNA excretion and progressive podocyte loss in kidney contribute to the high risk of long-term renal disease caused by preterm birth. Sci Rep 11:20650. https:\/\/doi.org\/10.1038\/s41598-021-00130-y","journal-title":"Sci Rep"},{"key":"6967_CR47","doi-asserted-by":"publisher","first-page":"2668","DOI":"10.1002\/ar.24369","volume":"303","author":"GD Gon\u00e7alves","year":"2020","unstructured":"Gon\u00e7alves GD, Walton SL, Gazzard SE, van der Wolde J, Mathias PCF, Moritz KM, Cullen-McEwen LA, Bertram JF (2020) Maternal hypoxia developmentally programs low podocyte endowment in male, but not female offspring. Anat Rec (Hoboken) 303:2668\u20132678. https:\/\/doi.org\/10.1002\/ar.24369","journal-title":"Anat Rec (Hoboken)"},{"key":"6967_CR48","doi-asserted-by":"publisher","first-page":"F322","DOI":"10.1152\/ajprenal.00029.2021","volume":"321","author":"LA Cullen-McEwen","year":"2021","unstructured":"Cullen-McEwen LA, van der Wolde J, Haruhara K, Tribolet L, Dowling JP, Bertram MG, De Matteo R, Haas F, Czogalla J, Okabayashi Y, Armitage JA, Black MJ, Hoy WE, Puelles VG, Bertram JF (2021) Podocyte endowment and the impact of adult body size on kidney health. Am J Physiol Renal Physiol 321:F322\u2013F334. https:\/\/doi.org\/10.1152\/ajprenal.00029.2021","journal-title":"Am J Physiol Renal Physiol"},{"key":"6967_CR49","doi-asserted-by":"publisher","first-page":"4542","DOI":"10.1038\/s41598-018-22733-8","volume":"8","author":"C Menendez-Castro","year":"2018","unstructured":"Menendez-Castro C, Nitz D, Cordasic N, Jordan J, B\u00e4uerle T, Fahlbusch FB, Rascher W, Hilgers KF, Hartner A (2018) Neonatal nephron loss during active nephrogenesis - detrimental impact with long-term renal consequences. Sci Rep 8:4542. https:\/\/doi.org\/10.1038\/s41598-018-22733-8","journal-title":"Sci Rep"},{"key":"6967_CR50","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/S1875-9572(09)60032-2","volume":"50","author":"CM Chen","year":"2009","unstructured":"Chen CM, Chou HC (2009) Effects of maternal undernutrition on glomerular ultrastructure in rat offspring. Pediatr Neonatol 50:50\u201353. https:\/\/doi.org\/10.1016\/S1875-9572(09)60032-2","journal-title":"Pediatr Neonatol"},{"key":"6967_CR51","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1007\/s00467-005-1828-6","volume":"20","author":"J Rodr\u00edguez-Soriano","year":"2005","unstructured":"Rodr\u00edguez-Soriano J, Aguirre M, Oliveros R, Vallo A (2005) Long-term renal follow-up of extremely low birth weight infants. Pediatr Nephrol 20:579\u2013584. https:\/\/doi.org\/10.1007\/s00467-005-1828-6","journal-title":"Pediatr Nephrol"},{"key":"6967_CR52","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1159\/000455828","volume":"7","author":"M Awazu","year":"2017","unstructured":"Awazu M, Arai M, Ohashi S, Takahashi H, Sekine T, Ikeda K (2017) Tubular dysfunction mimicking Dent\u2019s disease in 2 infants born with extremely low birth weight. Case Rep Nephrol Dial 7:13\u201317. https:\/\/doi.org\/10.1159\/000455828","journal-title":"Case Rep Nephrol Dial"},{"key":"6967_CR53","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1042\/bj3050675","volume":"305","author":"B Prieur","year":"1995","unstructured":"Prieur B, Cordeau-Lossouarn L, Rotig A, Bismuth J, Geloso JP, Delaval E (1995) Perinatal maturation of rat kidney mitochondria. Biochem J 305:675\u2013680. https:\/\/doi.org\/10.1042\/bj3050675","journal-title":"Biochem J"},{"key":"6967_CR54","doi-asserted-by":"publisher","first-page":"R759","DOI":"10.1152\/ajpregu.00523.2006","volume":"293","author":"N Ashton","year":"2007","unstructured":"Ashton N, Al-Wasil SH, Bond H, Berry JL, Denton J, Freemont AJ (2007) The effect of a low-protein diet in pregnancy on offspring renal calcium handling. Am J Physiol Regul Integr Comp Physiol 293:R759-765. https:\/\/doi.org\/10.1152\/ajpregu.00523.2006","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"6967_CR55","doi-asserted-by":"publisher","first-page":"F202","DOI":"10.1152\/ajprenal.00358.2001","volume":"283","author":"J Manning","year":"2002","unstructured":"Manning J, Beutler K, Knepper MA, Vehaskari VM (2002) Upregulation of renal BSC1 and TSC in prenatally programmed hypertension. Am J Physiol Renal Physiol 283:F202-206. https:\/\/doi.org\/10.1152\/ajprenal.00358.2001","journal-title":"Am J Physiol Renal Physiol"},{"key":"6967_CR56","doi-asserted-by":"publisher","first-page":"2841","DOI":"10.1210\/endo.142.7.8238","volume":"142","author":"C Bertram","year":"2001","unstructured":"Bertram C, Trowern AR, Copin N, Jackson AA, Whorwood CB (2001) The maternal diet during pregnancy programs altered expression of the glucocorticoid receptor and type 2 11\u00df-hydroxysteroid dehydrogenase: potential molecular mechanisms underlying the programming of hypertension in utero. Endocrinology 142:2841\u20132853. https:\/\/doi.org\/10.1210\/endo.142.7.8238","journal-title":"Endocrinology"},{"key":"6967_CR57","doi-asserted-by":"publisher","unstructured":"Guo Y, Lu Y, Wang J, Zhu L, Liu X (2020) Dysregulated ion channels and transporters activate endoplasmic reticulum stress in rat kidney of fetal growth restriction. Life Sci 259:118276 https:\/\/doi.org\/10.1016\/j.lfs.2020.118276.","DOI":"10.1016\/j.lfs.2020.118276"},{"key":"6967_CR58","doi-asserted-by":"publisher","first-page":"F583","DOI":"10.1152\/ajprenal.00164.2018","volume":"315","author":"W Abdulmahdi","year":"2018","unstructured":"Abdulmahdi W, Rabadi MM, Jules E, Marghani Y, Marji N, Leung J, Zhang F, Siani A, Siskind T, Vedovino K, Chowdhury N, Sekulic M, Ratliff BB (2018) Kidney dysfunction in the low-birth weight murine adult: implications of oxidative stress. Am J Physiol Renal Physiol 315:F583\u2013F594. https:\/\/doi.org\/10.1152\/ajprenal.00164.2018","journal-title":"Am J Physiol Renal Physiol"},{"key":"6967_CR59","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1007\/s10157-013-0896-3","volume":"18","author":"N Nishizaki","year":"2014","unstructured":"Nishizaki N, Hirano D, Nishizaki Y, Fujinaga S, Nagata S, Ohtomo Y, Kaneko K, Shimizu T (2014) Increased urinary angiotensinogen is an effective marker of chronic renal impairment in very low birth weight childre. Clin Exp Nephrol 18:642\u2013648. https:\/\/doi.org\/10.1007\/s10157-013-0896-3","journal-title":"Clin Exp Nephrol"},{"key":"6967_CR60","doi-asserted-by":"publisher","first-page":"R804","DOI":"10.1152\/ajpregu.00725.2006","volume":"293","author":"D Grigore","year":"2007","unstructured":"Grigore D, Ojeda NB, Robertson EB, Dawson AS, Huffman CA, Bourassa EA, Speth RC, Brosnihan KB, Alexander BT (2007) Placental insufficiency results in temporal alterations in the renin angiotensin system in male hypertensive growth restricted offspring. Am J Physiol Regul Integr Comp Physiol 293:R804\u2013R811. https:\/\/doi.org\/10.1152\/ajpregu.00725.2006","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"6967_CR61","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1203\/00006450-200104000-00005","volume":"49","author":"LL Woods","year":"2001","unstructured":"Woods LL, Ingelfinger JR, Nyengaard JR, Rasch R (2001) Maternal protein restriction suppresses the newborn renin-angiotensin system and programs adult hypertension in rats. Pediatr Res 49:460\u2013467. https:\/\/doi.org\/10.1203\/00006450-200104000-00005","journal-title":"Pediatr Res"},{"key":"6967_CR62","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1159\/000317739","volume":"33","author":"SH Alwasel","year":"2010","unstructured":"Alwasel SH, Kaleem I, Sahajpal V, Ashton N (2010) Maternal protein restriction reduces angiotensin II AT(1) and AT(2) receptor expression in the fetal rat kidney. Kidney Blood Press Res 33:251\u2013259. https:\/\/doi.org\/10.1159\/000317739","journal-title":"Kidney Blood Press Res"},{"key":"6967_CR63","doi-asserted-by":"publisher","first-page":"R1267","DOI":"10.1152\/ajpregu.00119.2007","volume":"293","author":"V Zohdi","year":"2007","unstructured":"Zohdi V, Moritz KM, Bubb KJ, Cock ML, Wreford N, Harding R, Black MJ (2007) Nephrogenesis and the renal renin-angiotensin system in fetal sheep: effects of intrauterine growth restriction during late gestation. Am J Physiol Regul Integr Comp Physiol 293:R1267-1273. https:\/\/doi.org\/10.1152\/ajpregu.00119.2007","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"6967_CR64","doi-asserted-by":"publisher","first-page":"e21232","DOI":"10.1371\/journal.pone.0021232","volume":"6","author":"R Luzardo","year":"2011","unstructured":"Luzardo R, Silva PA, Einicker-Lamas M, Ortiz-Costa S, do Carmo Mda G, Vieira-Filho LD, Paix\u00e3o AD, Lara LS, Vieyra A (2011) Metabolic programming during lactation stimulates renal Na+ transport in the adult offspring due to an early impact on local angiotensin II pathways. PLoS ONE 6:e21232. https:\/\/doi.org\/10.1371\/journal.pone.0021232","journal-title":"PLoS ONE"},{"key":"6967_CR65","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1042\/CS20020355","volume":"104","author":"V Sahajpal","year":"2003","unstructured":"Sahajpal V, Ashton N (2003) Renal function and angiotensin AT1 receptor expression in young rats following intrauterine exposure to a maternal low-protein diet. Clin Sci (London) 104:607\u2013614. https:\/\/doi.org\/10.1042\/CS20020355","journal-title":"Clin Sci (London)"},{"key":"6967_CR66","doi-asserted-by":"publisher","first-page":"R791","DOI":"10.1152\/ajpregu.00791.2010","volume":"300","author":"MM Kett","year":"2011","unstructured":"Kett MM, Denton KM (2011) Renal programming: cause for concern? Am J Physiol Regul Integr Comp Physiol 300:R791-803. https:\/\/doi.org\/10.1152\/ajpregu.00791.2010","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"6967_CR67","doi-asserted-by":"publisher","first-page":"1212","DOI":"10.1111\/j.1440-1681.2007.04754.x","volume":"34","author":"NB Ojeda","year":"2007","unstructured":"Ojeda NB, Johnson WR, Dwyer TM, Alexander BT (2007) Early renal denervation prevents development of hypertension in growth-restricted offspring. Clin Exp Pharmacol Physiol 34:1212\u20131216. https:\/\/doi.org\/10.1111\/j.1440-1681.2007.04754.x","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"6967_CR68","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1161\/01.HYP.0000153319.20340.2a","volume":"45","author":"BT Alexander","year":"2005","unstructured":"Alexander BT, Hendon AE, Ferril G, Dwyer TM (2005) Renal denervation abolishes hypertension in low-birth-weight offspring from pregnant rats with reduced uterine perfusion. Hypertension 45:754\u2013758. https:\/\/doi.org\/10.1161\/01.HYP.0000153319.20340.2a","journal-title":"Hypertension"},{"key":"6967_CR69","doi-asserted-by":"publisher","first-page":"828","DOI":"10.1161\/HYPERTENSIONAHA.111.00645","volume":"61","author":"S Intapad","year":"2013","unstructured":"Intapad S, Tull FL, Brown AD, Dasinger JH, Ojeda NB, Fahling JM, Alexander BT (2013) Renal denervation abolishes the age-dependent increase in blood pressure in female intrauterine growth-restricted rats at 12 months of age. Hypertension 61:828\u2013834. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.111.00645","journal-title":"Hypertension"},{"key":"6967_CR70","doi-asserted-by":"publisher","first-page":"F29","DOI":"10.1152\/ajprenal.00123.2008","volume":"295","author":"A Dagan","year":"2008","unstructured":"Dagan A, Kwon HM, Dwarakanath V, Baum M (2008) Effect of renal denervation on prenatal programming of hypertension and renal tubular transporter abundance. Am J Physiol Renal Physiol 295:F29-34. https:\/\/doi.org\/10.1152\/ajprenal.00123.2008","journal-title":"Am J Physiol Renal Physiol"},{"key":"6967_CR71","doi-asserted-by":"publisher","first-page":"1080","DOI":"10.1161\/CIRCRESAHA.118.313266","volume":"123","author":"JM Tang","year":"2018","unstructured":"Tang JM, Shi N, Dong K, Brown SA, Coleman AE, Boegehold MA, Chen SY (2018) Response gene to complement 32 maintains blood pressure homeostasis by regulating \u03b1-adrenergic receptor expression. Circ Res 123:1080\u20131090. https:\/\/doi.org\/10.1161\/CIRCRESAHA.118.313266","journal-title":"Circ Res"},{"key":"6967_CR72","doi-asserted-by":"publisher","unstructured":"Rodr\u00edguez-Rodr\u00edguez P, Ramiro-Cortijo D, Reyes-Hern\u00e1ndez CG, L\u00f3pez de Pablo AL, Gonz\u00e1lez MC, Arribas SM (2018) Implication of oxidative stress in fetal programming of cardiovascular disease. Front Physiol 9:602 https:\/\/doi.org\/10.3389\/fphys.2018.00602","DOI":"10.3389\/fphys.2018.00602"},{"key":"6967_CR73","doi-asserted-by":"publisher","first-page":"2180","DOI":"10.1111\/j.1523-1755.2005.00674.x","volume":"68","author":"T Stewart","year":"2005","unstructured":"Stewart T, Jung FF, Manning J, Vehaskari VM (2005) Kidney immune cell infiltration and oxidative stress contribute to prenatally programmed hypertension. Kidney Int 68:2180\u20132188. https:\/\/doi.org\/10.1111\/j.1523-1755.2005.00674.x","journal-title":"Kidney Int"},{"key":"6967_CR74","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/s0008-6363(02)00508-4","volume":"56","author":"C Franco Mdo","year":"2002","unstructured":"Franco Mdo C, Arruda RM, Dantas AP, Kawamoto EM, Fortes ZB, Scavone C, Carvalho MH, Tostes RC, Nigro D (2002) Intrauterine undernutrition: expression and activity of the endothelial nitric oxide synthase in male and female adult offspring. Cardiovasc Res 56:145\u2013153. https:\/\/doi.org\/10.1016\/s0008-6363(02)00508-4","journal-title":"Cardiovasc Res"},{"key":"6967_CR75","doi-asserted-by":"publisher","first-page":"L860","DOI":"10.1152\/ajplung.00197.2011","volume":"301","author":"PJ Rozance","year":"2011","unstructured":"Rozance PJ, Seedorf GJ, Brown A, Roe G, O\u2019Meara MC, Gien J, Tang JR, Abman SH (2011) Intrauterine growth restriction decreases pulmonary alveolar and vessel growth and causes pulmonary artery endothelial cell dysfunction in vitro in fetal sheep. Am J Physiol Lung Cell Mol Physiol 301:L860-871. https:\/\/doi.org\/10.1152\/ajplung.00197.2011","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"6967_CR76","doi-asserted-by":"publisher","unstructured":"Guo H, Xu D, Kuroki M, Lu Z, Xu X, Geurts A, Osborn JW, Chen Y (2020) Kidney failure, arterial hypertension and left ventricular hypertrophy in rats with loss of function mutation of SOD3. Free Radic Biol Med 152:787\u2013796 https:\/\/doi.org\/10.1016\/j.freeradbiomed.2020.01.023","DOI":"10.1016\/j.freeradbiomed.2020.01.023"},{"key":"6967_CR77","doi-asserted-by":"publisher","unstructured":"Sah SK, Agrahari G, Kim TY (2020) Insights into superoxide dismutase 3 in regulating biological and functional properties of mesenchymal stem cells. Cell Biosci 10:22 https:\/\/doi.org\/10.1186\/s13578-020-00386-3","DOI":"10.1186\/s13578-020-00386-3"},{"key":"6967_CR78","doi-asserted-by":"publisher","first-page":"e13625","DOI":"10.11111\/eci.13625","volume":"51","author":"LF Grilo","year":"2021","unstructured":"Grilo LF, Tocantins C, Diniz MS, Gomes RM, Oliveira PJ, Matafome P, Pereira SP (2021) Metabolic disease programming: from mitochondria to epigenetics, glucocorticoid signalling and beyond. Eur J Clin Invest 51:e13625. https:\/\/doi.org\/10.11111\/eci.13625","journal-title":"Eur J Clin Invest"},{"key":"6967_CR79","doi-asserted-by":"publisher","first-page":"F1217","DOI":"10.1152\/ajprenal.00419.2014","volume":"308","author":"SP Pereira","year":"2015","unstructured":"Pereira SP, Oliveira PJ, Tavares LC, Moreno AJ, Cox LA, Nathanielsz PW, Nijland MJ (2015) Effects of moderate global maternal nutrient reduction on fetal baboon renal mitochondrial gene expression at 0.9 gestation. Am J Physiol Renal Physiol 308:F1217-1228. https:\/\/doi.org\/10.1152\/ajprenal.00419.2014","journal-title":"Am J Physiol Renal Physiol"},{"key":"6967_CR80","doi-asserted-by":"publisher","first-page":"F1189","DOI":"10.1152\/ajprenal.00638.2014","volume":"308","author":"S Stangenberg","year":"2015","unstructured":"Stangenberg S, Chen H, Wong MG, Pollock CA, Saad S (2015) Fetal programming of chronic kidney disease: the role of maternal smoking, mitochondrial dysfunction, and epigenetic modfification. Am J Physiol Renal Physiol 308:F1189-1196. https:\/\/doi.org\/10.1152\/ajprenal.00638.2014","journal-title":"Am J Physiol Renal Physiol"},{"key":"6967_CR81","doi-asserted-by":"publisher","first-page":"3254","DOI":"10.1096\/fj.201701080R","volume":"32","author":"AG Woodman","year":"2018","unstructured":"Woodman AG, Mah R, Keddie D, Noble RMN, Panahi S, Gragasin FS, Lemieux H, Bourque SL (2018) Prenatal iron deficiency causes sex-dependent mitochondrial dysfunction and oxidative stress in fetal rat kidneys and liver. FASEB J 32:3254\u20133263. https:\/\/doi.org\/10.1096\/fj.201701080R","journal-title":"FASEB J"},{"key":"6967_CR82","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1017\/S2040174418000296","volume":"9","author":"IKM Watanabe","year":"2018","unstructured":"Watanabe IKM, Jara ZP, Volpini RA, Franco MDC, Jung FF, Casarini DE (2018) Up-regulation of renal renin-angiotensin system and inflammatory mechanisms in the prenatal programming by low-protein diet: beneficial effect of the post-weaning losartan treatment. J Dev Orig Health Dis 9:530\u2013535. https:\/\/doi.org\/10.1017\/S2040174418000296","journal-title":"J Dev Orig Health Dis"},{"key":"6967_CR83","doi-asserted-by":"publisher","first-page":"e193","DOI":"10.1097\/MPG.0000000000001196","volume":"63","author":"L Ruiz","year":"2016","unstructured":"Ruiz L, Moles L, Gueimonde M, Rodriguez JM (2016) Perinatal microbiomes\u2019 influence on preterm birth and preterms\u2019 health: Influencing factors and modulation strategies. J Pediatr Gastroenterol Nutr 63:e193\u2013e203. https:\/\/doi.org\/10.1097\/MPG.0000000000001196","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"6967_CR84","doi-asserted-by":"publisher","unstructured":"Cosola C, Rocchetti MT, Cupisti A, Gesualdo L (2018) Microbiota metabolites: pivotal players of cardiovascular damage in chronic kidney disease. Pharmacol Res 130:132\u2013142 https:\/\/doi.org\/10.1016\/j.phrs.2018.03.003","DOI":"10.1016\/j.phrs.2018.03.003"},{"key":"6967_CR85","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1038\/s41390-020-1022-3","volume":"89","author":"S Tsuji","year":"2021","unstructured":"Tsuji S, Akagawa S, Akagawa Y, Yamaguchi T, Kino J, Yamanouchi S, Kimata T, Hashiyada M, Akane A, Kaneko K (2021) Idiopathic nephrotic syndrome in children: role of regulatory T cells and gut microbiota. Pediatr Res 89:1185\u20131191. https:\/\/doi.org\/10.1038\/s41390-020-1022-3","journal-title":"Pediatr Res"},{"key":"6967_CR86","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1038\/nrcardio.2017.120","volume":"15","author":"FZ Marques","year":"2018","unstructured":"Marques FZ, Mackay CR, Kaye DM (2018) Beyond gut feelings: how the gut microbiota regulates blood pressure. Nat Rev Cardiol 15:20\u201332. https:\/\/doi.org\/10.1038\/nrcardio.2017.120","journal-title":"Nat Rev Cardiol"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-021-06967-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11033-021-06967-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-021-06967-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,22]],"date-time":"2022-02-22T07:19:38Z","timestamp":1645514378000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11033-021-06967-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,24]]},"references-count":86,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["6967"],"URL":"https:\/\/doi.org\/10.1007\/s11033-021-06967-w","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,24]]},"assertion":[{"value":"14 September 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 November 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 November 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants of animals performed by the author.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Research involving human and animal rights"}}]}}