{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:28:54Z","timestamp":1772119734587,"version":"3.50.1"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2022,3,19]],"date-time":"2022-03-19T00:00:00Z","timestamp":1647648000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,3,19]],"date-time":"2022-03-19T00:00:00Z","timestamp":1647648000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"st. marianna university school of medicine research grant"},{"DOI":"10.13039\/501100001691","name":"japan society for the promotion of science","doi-asserted-by":"publisher","award":["JP20K08500"],"award-info":[{"award-number":["JP20K08500"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1007\/s11033-022-07358-5","type":"journal-article","created":{"date-parts":[[2022,3,19]],"date-time":"2022-03-19T00:34:46Z","timestamp":1647650086000},"page":"5831-5842","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Prenatal glucocorticoid administration accelerates the maturation of fetal rat hepatocytes"],"prefix":"10.1007","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9871-169X","authenticated-orcid":false,"given":"Tsukasa","family":"Kobayashi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuko","family":"Takeba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Ohta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanori","family":"Ootaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Kida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minoru","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taroh","family":"Iiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,3,19]]},"reference":[{"key":"7358_CR1","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1265\/jjh.71.41","volume":"71","author":"F Sata","year":"2016","unstructured":"Sata F (2016) Developmental origins of health and disease (DOHaD) and epidemiology. Jpn J Hyg 71:41\u201346. https:\/\/doi.org\/10.1265\/jjh.71.41 (In Japanese)","journal-title":"Jpn J Hyg"},{"key":"7358_CR2","doi-asserted-by":"publisher","first-page":"31396","DOI":"10.1038\/srep31396","volume":"6","author":"Y Takemoto","year":"2016","unstructured":"Takemoto Y, Ota E, Yoneoka D, Mori R, Takeda S (2016) Japanese secular trends in birthweight and the prevalence of low birthweight infants during the last three decades: a population-based study. Sci Rep 6:31396. https:\/\/doi.org\/10.1038\/srep31396","journal-title":"Sci Rep"},{"key":"7358_CR3","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1080\/15592294.2016.1144006","volume":"11","author":"B Khulan","year":"2016","unstructured":"Khulan B, Liu L, Rose CM, Boyle AK, Manning JR, Drake AJ (2016) Glucocorticoids accelerate maturation of the heme pathway in fetal liver through effects on transcription and DNA methylation. Epigenetics 11:103\u2013109. https:\/\/doi.org\/10.1080\/15592294.2016.1144006","journal-title":"Epigenetics"},{"key":"7358_CR4","doi-asserted-by":"publisher","first-page":"R125","DOI":"10.1530\/JME-13-0204","volume":"52","author":"EA Rog-Zielinska","year":"2014","unstructured":"Rog-Zielinska EA, Richardson RV, Denvir MA, Chapman KE (2014) Glucocorticoids and foetal heart maturation; implications for prematurity and foetal programming. J Mol Endocrinol 52:R125\u2013R135. https:\/\/doi.org\/10.1530\/JME-13-0204","journal-title":"J Mol Endocrinol"},{"key":"7358_CR5","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1097\/AOG.0b013e318169ce2d","volume":"111","author":"EJ Hayes","year":"2008","unstructured":"Hayes EJ, Paul DA, Stahl GE, Seibel-Seamon J, Dysart K, Leiby BE, Mackley AB, Berghella V (2008) Effect of antenatal corticosteroids on survival for neonates born at 23 weeks of gestation. Obstet Gynecol 111:921\u2013926. https:\/\/doi.org\/10.1097\/AOG.0b013e318169ce2d","journal-title":"Obstet Gynecol"},{"key":"7358_CR6","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/j.lfs.2009.06.017","volume":"85","author":"Y Tsuzuki","year":"2009","unstructured":"Tsuzuki Y, Takeba Y, Kumai T, Matsumoto N, Mizuno M, Murano K, Asoh K, Takagi M, Yamamoto H, Kobayashi S (2009) Antenatal glucocorticoid therapy increase cardiac a-enolase levels infetus and neonate rats. Life Sci 85:609\u2013616. https:\/\/doi.org\/10.1016\/j.lfs.2009.06.017","journal-title":"Life Sci"},{"key":"7358_CR7","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1053\/j.sempedsurg.2013.10.006","volume":"22","author":"J Grijalva","year":"2013","unstructured":"Grijalva J, Vakili K (2013) Neonatal liver physiology. Semin Pediatr Surg 22:185\u2013189. https:\/\/doi.org\/10.1053\/j.sempedsurg.2013.10.006","journal-title":"Semin Pediatr Surg"},{"key":"7358_CR8","first-page":"0319","volume":"2015","author":"P Woodgate","year":"2015","unstructured":"Woodgate P, Jardine LA (2015) Neonatal jaundice: phototherapy. BMJ. Clin Evid 2015:0319","journal-title":"Clin Evid"},{"key":"7358_CR9","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1203\/00006450-199907000-00003","volume":"46","author":"PA Gruppuso","year":"1999","unstructured":"Gruppuso PA, Bienieki TC, Faris RA (1999) The relationship between differentiation and proliferation in late gestation fetal rat hepatocytes. Pediatr Res 46:14\u201319. https:\/\/doi.org\/10.1203\/00006450-199907000-00003","journal-title":"Pediatr Res"},{"key":"7358_CR10","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1002\/jcp.1041290112","volume":"129","author":"H Baribault","year":"1986","unstructured":"Baribault H, Marceau N (1986) Dexamethasone and dimethylsulfoxide as distinct regulators of growth and differentiation of cultured suckling rat hepatocytes. J Cell Physiol 129:77\u201384. https:\/\/doi.org\/10.1002\/jcp.1041290112","journal-title":"J Cell Physiol"},{"key":"7358_CR11","doi-asserted-by":"publisher","first-page":"81","DOI":"10.3727\/000000001783986945","volume":"10","author":"SPS Monga","year":"2001","unstructured":"Monga SPS, Tang Y, Candotti F, Rashid A, Wildner O, Mishra B, Iqbal S, Mishra L (2001) Expansion of hepatic and hematopoietic stem cells utilizing mouse embryonic liver explants. Cell Transplant 10:81\u201389. https:\/\/doi.org\/10.3727\/000000001783986945","journal-title":"Cell Transplant"},{"key":"7358_CR12","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1634\/stemcells.2008-0963","volume":"27","author":"S Snykers","year":"2009","unstructured":"Snykers S, De Kock J, Rogiers V, Vanhaecke T (2009) In vitro differentiation of embryonic and adult stem cells into hepatocytes: state of the art. Stem Cells 27:577\u2013605. https:\/\/doi.org\/10.1634\/stemcells.2008-0963","journal-title":"Stem Cells"},{"key":"7358_CR13","doi-asserted-by":"publisher","first-page":"152664","DOI":"10.1016\/j.tox.2020.152664","volume":"449","author":"D Zhang","year":"2021","unstructured":"Zhang D, Liu K, Hu W, Lu X, Li L, Zhang Q, Huang H, Wang H (2021) Prenatal dexamethasone exposure caused fetal rats liver dysplasia by inhibiting autophagy-mediated cell proliferation. Toxicology 449:152664. https:\/\/doi.org\/10.1016\/j.tox.2020.152664","journal-title":"Toxicology"},{"key":"7358_CR14","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1203\/00006450-200301000-00017","volume":"53","author":"H Ozdemir","year":"2003","unstructured":"Ozdemir H, Guvenal T, Cetin M, Kaya T, Cetin A (2003) A placebo-controlled comparison of effects of repetitive doses of betamethasone and dexamethasone on lung maturation and lung, liver, and body weights of mouse pups. Pediatr Res 53:98\u2013103. https:\/\/doi.org\/10.1203\/00006450-200301000-00017","journal-title":"Pediatr Res"},{"key":"7358_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000241200","volume":"36","author":"L Frank","year":"1979","unstructured":"Frank L, Roberts RJ (1979) Effects of low-dose prenatal corticosteroid administration on the premature rat. Biol Neonate 36:1\u20139. https:\/\/doi.org\/10.1159\/000241200","journal-title":"Biol Neonate"},{"key":"7358_CR16","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1159\/000143402","volume":"29","author":"S Sell","year":"2008","unstructured":"Sell S (2008) Alpha-fetoprotein, stem cells and cancer: how study of the production of alpha-fetoprotein during chemical hepatocarcinogenesis led to reaffirmation of the stem cell theory of cancer. Tumour Biol 29:161\u2013180. https:\/\/doi.org\/10.1159\/000143402","journal-title":"Tumour Biol"},{"key":"7358_CR17","doi-asserted-by":"publisher","first-page":"2127","DOI":"10.1093\/emboj\/18.8.2127","volume":"18","author":"A Kamiya","year":"1999","unstructured":"Kamiya A, Kinoshita T, Ito Y, Matsui T, Morikawa Y, Senba E, Nakashima K, Taga T, Yoshida K, Kishimoto T, Miyajima A (1999) Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer. EMBO J 18:2127\u20132136. https:\/\/doi.org\/10.1093\/emboj\/18.8.2127","journal-title":"EMBO J"},{"key":"7358_CR18","doi-asserted-by":"publisher","first-page":"1297","DOI":"10.1111\/j.1365-2443.2004.00809.x","volume":"9","author":"K Asahina","year":"2004","unstructured":"Asahina K, Fujimori H, Shimizu-Saito K, Kumashiro Y, Okamura K, Tanaka Y, Teramoto K, Arii S, Teraoka H (2004) Expression of the liver-specific gene Cyp7a1 reveals hepatic differentiation in embryoid bodies derived from mouse embryonic stem cells. Genes Cells 9:1297\u20131308. https:\/\/doi.org\/10.1111\/j.1365-2443.2004.00809.x","journal-title":"Genes Cells"},{"key":"7358_CR19","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1002\/(SICI)1097-0029(19971115)39:4<328::AID-JEMT3>3.0.CO;2-D","volume":"39","author":"N Shiojiri","year":"1997","unstructured":"Shiojiri N (1997) Development and differentiation of bile ducts in the mammalian liver. Microsc Res Tech 39:328\u2013335. https:\/\/doi.org\/10.1002\/(SICI)1097-0029(19971115)39:4%3c328::AID-JEMT3%3e3.0.CO;2-D","journal-title":"Microsc Res Tech"},{"key":"7358_CR20","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1124\/jpet.105.095851","volume":"317","author":"MN Samtani","year":"2006","unstructured":"Samtani MN, Pyszczynski NA, Dubois DC, Almon RR, Jusko WJ (2006) Modeling glucocorticoid-mediated fetal lung maturation: I. Temporal patterns of corticosteroids in rat pregnancy. J Pharmacol Exp Ther 317:117\u2013126. https:\/\/doi.org\/10.1124\/jpet.105.095851","journal-title":"J Pharmacol Exp Ther"},{"key":"7358_CR21","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1124\/jpet.105.095869","volume":"317","author":"MN Samtani","year":"2006","unstructured":"Samtani MN, Pyszczynski NA, Dubois DC, Almon RR, Jusko WJ (2006) Modeling glucocorticoid-mediated fetal lung maturation: II. Temporal patterns of gene expression in fetal rat lung. J Pharmacol Exp Ther 317:127\u2013138. https:\/\/doi.org\/10.1124\/jpet.105.095869","journal-title":"J Pharmacol Exp Ther"},{"key":"7358_CR22","doi-asserted-by":"publisher","first-page":"61","DOI":"10.4103\/2249-4847.116402","volume":"2","author":"VK Bhutani","year":"2013","unstructured":"Bhutani VK, Wong RJ (2013) Bilirubin neurotoxicity in preterm infants: risk and prevention. J Clin Neonatol 2:61\u201369. https:\/\/doi.org\/10.4103\/2249-4847.116402","journal-title":"J Clin Neonatol"},{"key":"7358_CR23","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.20550.1","author":"K Wynne","year":"2020","unstructured":"Wynne K, Rowe C, Delbridge M, Watkins B, Brown K, Addley J, Woods A, Murray H (2020) Antenatal corticosteroid administration for foetal lung maturation. F1000 Res. https:\/\/doi.org\/10.12688\/f1000research.20550.1","journal-title":"F1000 Res"},{"key":"7358_CR24","doi-asserted-by":"publisher","first-page":"R61","DOI":"10.1530\/JME-18-0077","volume":"61","author":"EJ Agnew","year":"2018","unstructured":"Agnew EJ, Ivy JR, Stock SJ, Chapman KE (2018) Glucocorticoids, antenatal corticosteroid therapy and fetal heart maturation. J Mol Endocrinol 61:R61\u2013R73. https:\/\/doi.org\/10.1530\/JME-18-0077","journal-title":"J Mol Endocrinol"},{"key":"7358_CR25","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1002\/(SICI)1520-6661(200003\/04)9:2<131::AID-MFM9>3.0.CO;2-M","volume":"9","author":"LM Smith","year":"2000","unstructured":"Smith LM, Qureshi N, Chao CR (2000) Effects of single and multiple courses of antenatal glucocorticoids in preterm newborns less than 30 weeks\u2019 gestation. J Matern Fetal Med 9:131\u2013135. https:\/\/doi.org\/10.1002\/(SICI)1520-6661(200003\/04)9:2%3c131::AID-MFM9%3e3.0.CO;2-M","journal-title":"J Matern Fetal Med"},{"key":"7358_CR26","first-page":"281","volume":"45","author":"Y Takeba","year":"2018","unstructured":"Takeba Y, Sakurai K, Osada Y, Mizuno M, Tsuzuki Y, Ohta Y, Ootaki M, Watanabe M, Machida T, Watanabe D, Nakamura Y, Kobayashi T, Iiri T, Matsumoto N (2018) Production of bilirubin transporters, multidrug resistance-associated protein 2 in the fetal rat liver with antenatal glucocorticoid administration. St Marianna Med J 45:281\u2013287 (In Japanese)","journal-title":"St Marianna Med J"},{"key":"7358_CR27","doi-asserted-by":"publisher","first-page":"55","DOI":"10.3727\/000000003108748964","volume":"11","author":"GK Michalopoulos","year":"2003","unstructured":"Michalopoulos GK, Bowen WC, Mul\u00e8 K, Luo J (2003) HGF-, EGF-, and dexamethasone-induced gene expression patterns during formation of tissue in hepatic organoid cultures. Gene Expr 11:55\u201375. https:\/\/doi.org\/10.3727\/000000003108748964","journal-title":"Gene Expr"},{"key":"7358_CR28","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/s0232-1513(82)80039-x","volume":"21","author":"T Daimon","year":"1982","unstructured":"Daimon T, David H, von Zglinicki T, Marx I (1982) Correlated ultrastructural and morphometric studies on the liver during prenatal development of rats. Exp Pathol 21:237\u2013250. https:\/\/doi.org\/10.1016\/s0232-1513(82)80039-x","journal-title":"Exp Pathol"},{"key":"7358_CR29","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1016\/j.molcel.2014.02.028","volume":"53","author":"K Yamamoto","year":"2014","unstructured":"Yamamoto K, Gandin V, Sasaki M, McCracken S, Li W, Silvester JL, Elia AJ, Wang F, Wakutani Y, Alexandrova R, Oo YD, Mullen PJ, Inoue S, Itsumi M, Lapin V, Haight J, Wakeham A, Shahinian A, Ikura M, Topisirovic I, Sonenberg N, Mak TW (2014) Largen: a molecular regulator of mammalian cell size control. Mol Cell 53:904\u2013915. https:\/\/doi.org\/10.1016\/j.molcel.2014.02.028","journal-title":"Mol Cell"},{"key":"7358_CR30","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/1747-1028-8-8","volume":"8","author":"Y Miyaoka","year":"2013","unstructured":"Miyaoka Y, Miyajima A (2013) To divide or not to divide: revisiting liver regeneration. Cell Div 8:8. https:\/\/doi.org\/10.1186\/1747-1028-8-8","journal-title":"Cell Div"},{"key":"7358_CR31","first-page":"335","volume":"5","author":"LA Porter","year":"2003","unstructured":"Porter LA, Donoghue DJ (2003) Cyclin B1 and CDK1: nuclear localization and upstream regulators. Prog Cell Cycle Res 5:335\u2013347","journal-title":"Prog Cell Cycle Res"},{"key":"7358_CR32","doi-asserted-by":"publisher","first-page":"G45","DOI":"10.1152\/ajpgi.00465.2005","volume":"291","author":"NM Masson","year":"2006","unstructured":"Masson NM, Currie IS, Terrace JD, Garden OJ, Parks RW, Ross JA (2006) Hepatic progenitor cells in human fetal liver express the oval cell marker Thy-1. Am J Physiol Gastrointest Liver Physiol 291:G45\u2013G54. https:\/\/doi.org\/10.1152\/ajpgi.00465.2005","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"7358_CR33","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1080\/15384101.2015.1120925","volume":"15","author":"S Ruijtenberg","year":"2016","unstructured":"Ruijtenberg S, van den Heuvel S (2016) Coordinating cell proliferation and differentiation: antagonism between cell cycle regulators and cell type-specific gene expression. Cell Cycle 15:196\u2013212. https:\/\/doi.org\/10.1080\/15384101.2015.1120925","journal-title":"Cell Cycle"},{"key":"7358_CR34","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1053\/jhep.2003.50007","volume":"37","author":"HC Fiegel","year":"2003","unstructured":"Fiegel HC, Park JJ, Lioznov MV, Martin A, Jaeschke-Melli S, Kaufmann PM, Fehse B, Zander AR, Kluth D (2003) Characterization of cell types during rat liver development. Hepatology 37:148\u2013154. https:\/\/doi.org\/10.1053\/jhep.2003.50007","journal-title":"Hepatology"},{"key":"7358_CR35","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1093\/jb\/mvs069","volume":"152","author":"H Nishina","year":"2012","unstructured":"Nishina H (2012) hDlk-1: a cell surface marker common to normal hepatic stem\/progenitor cells and carcinomas. J Biochem 152:121\u2013123. https:\/\/doi.org\/10.1093\/jb\/mvs069","journal-title":"J Biochem"},{"key":"7358_CR36","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.modgep.2004.08.003","volume":"5","author":"N Tanimizu","year":"2004","unstructured":"Tanimizu N, Tsujimura T, Takahide K, Kodama T, Nakamura K, Miyajima A (2004) Expression of Dlk\/Pref-1 defines a subpopulation in the oval cell compartment of rat liver. Gene Expr Patterns 5:209\u2013218. https:\/\/doi.org\/10.1016\/j.modgep.2004.08.003","journal-title":"Gene Expr Patterns"},{"key":"7358_CR37","doi-asserted-by":"publisher","first-page":"1528","DOI":"10.1002\/hep.22510","volume":"48","author":"C Yin","year":"2008","unstructured":"Yin C, Lin Y, Zhang X, Chen YX, Zeng X, Yue HY, Hou JL, Deng X, Zhang JP, Han ZG, Xie WF (2008) Differentiation therapy of hepatocellular carcinoma in mice with recombinant adenovirus carrying hepatocyte nuclear factor-4alpha gene. Hepatology 48:1528\u20131539. https:\/\/doi.org\/10.1002\/hep.22510","journal-title":"Hepatology"},{"key":"7358_CR38","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1016\/0092-8674(81)90436-0","volume":"23","author":"E Derman","year":"1981","unstructured":"Derman E, Krauter K, Walling L, Weinberger C, Ray M, Darnell JE Jr (1981) Transcriptional control in the production of liver-specific mRNAs. Cell 23:731\u2013739. https:\/\/doi.org\/10.1016\/0092-8674(81)90436-0","journal-title":"Cell"},{"key":"7358_CR39","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.1101\/gad.1.10.1172","volume":"1","author":"A Panduro","year":"1987","unstructured":"Panduro A, Shalaby F, Shafritz DA (1987) Changing patterns of transcriptional and post-transcriptional control of liver-specific gene expression during rat development. Genes Dev 1:1172\u20131182. https:\/\/doi.org\/10.1101\/gad.1.10.1172","journal-title":"Genes Dev"},{"key":"7358_CR40","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1387\/ijdb.15005571","volume":"48","author":"A Jochheim","year":"2004","unstructured":"Jochheim A, Hillemann T, Kania G, Scharf J, Attaran M, Manns MP, Wobus AM, Ott M (2004) Quantitative gene expression profiling reveals a fetal hepatic phenotype of murine ES-derived hepatocytes. Int J Dev Biol 48:23\u201329. https:\/\/doi.org\/10.1387\/ijdb.15005571","journal-title":"Int J Dev Biol"},{"key":"7358_CR41","doi-asserted-by":"publisher","first-page":"2051","DOI":"10.1002\/jcp.22934","volume":"227","author":"W Zhang","year":"2012","unstructured":"Zhang W, Li W, Liu B, Wang P, Li W, Zhang H (2012) Efficient generation of functional hepatocyte-like cells from human fetal hepatic progenitor cells in vitro. J Cell Physiol 227:2051\u20132058. https:\/\/doi.org\/10.1002\/jcp.22934","journal-title":"J Cell Physiol"},{"key":"7358_CR42","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1111\/j.1432-0436.2005.00019.x","volume":"73","author":"S Nava","year":"2005","unstructured":"Nava S, Westgren M, Jaksch M, Tibell A, Broom\u00e9 U, Ericzon BG, Sumitran-Holgersson S (2005) Characterization of cells in the developing human liver. Differentiation 73:249\u2013260. https:\/\/doi.org\/10.1111\/j.1432-0436.2005.00019.x","journal-title":"Differentiation"},{"key":"7358_CR43","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/s0014-5793(01)02140-8","volume":"492","author":"A Kamiya","year":"2001","unstructured":"Kamiya A, Kinoshita T, Miyajima A (2001) Oncostatin M and hepatocyte growth factor induce hepatic maturation via distinct signaling pathways. FEBS Lett 492:90\u201394. https:\/\/doi.org\/10.1016\/s0014-5793(01)02140-8","journal-title":"FEBS Lett"},{"key":"7358_CR44","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1101\/gad.14.4.464","volume":"14","author":"J Li","year":"2000","unstructured":"Li J, Ning G, Duncan SA (2000) Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha. Genes Dev 14:464\u2013474. https:\/\/doi.org\/10.1101\/gad.14.4.464","journal-title":"Genes Dev"},{"key":"7358_CR45","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1038\/ng1175","volume":"34","author":"F Parviz","year":"2003","unstructured":"Parviz F, Matullo C, Garrison WD, Savatski L, Adamson JW, Ning G, Kaestner KH, Rossi JM, Zaret KS, Duncan SA (2003) Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis. Nat Genet 34:292\u2013296. https:\/\/doi.org\/10.1038\/ng1175","journal-title":"Nat Genet"},{"key":"7358_CR46","doi-asserted-by":"publisher","first-page":"337","DOI":"10.3727\/105221610x12717040569901","volume":"14","author":"S Dean","year":"2010","unstructured":"Dean S, Tang JI, Seckl JR, Nyirenda MJ (2010) Developmental and tissue-specific regulation of hepatocyte nuclear factor 4-alpha (HNF4-alpha) isoforms in rodents. Gene Expr 14:337\u2013344. https:\/\/doi.org\/10.3727\/105221610x12717040569901","journal-title":"Gene Expr"},{"key":"7358_CR47","doi-asserted-by":"publisher","first-page":"1412","DOI":"10.1007\/s00125-006-0188-5","volume":"49","author":"MJ Nyirenda","year":"2006","unstructured":"Nyirenda MJ, Dean S, Lyons V, Chapman KE, Seckl JR (2006) Prenatal programming of hepatocyte nuclear factor 4alpha in the rat: a key mechanism in the \u201cfoetal origins of hyperglycaemia\u201d? Diabetologia 49:1412\u20131420. https:\/\/doi.org\/10.1007\/s00125-006-0188-5","journal-title":"Diabetologia"},{"key":"7358_CR48","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1007\/s00134-009-1468-6","volume":"35","author":"EL Van den Akker","year":"2009","unstructured":"Van den Akker EL, Koper JW, Joosten K, de Jong FH, Hazelzet JA, Lamberts SW, Hokken-Koelega AC (2009) Glucocorticoid receptor mRNA levels are selectively decreased in neutrophils of children with sepsis. Intensive Care Med 35:1247\u20131254. https:\/\/doi.org\/10.1007\/s00134-009-1468-6","journal-title":"Intensive Care Med"},{"key":"7358_CR49","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2001077","author":"D Duma","year":"2010","unstructured":"Duma D, Collins JB, Chou JW, Cidlowski JA (2010) Sexually dimorphic actions of glucocorticoids provide a link to inflammatory diseases with gender differences in prevalence. Sci Signal. https:\/\/doi.org\/10.1126\/scisignal.2001077","journal-title":"Sci Signal"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-022-07358-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11033-022-07358-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-022-07358-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,8]],"date-time":"2022-07-08T15:21:31Z","timestamp":1657293691000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11033-022-07358-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,19]]},"references-count":49,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["7358"],"URL":"https:\/\/doi.org\/10.1007\/s11033-022-07358-5","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-808689\/v1","asserted-by":"object"},{"id-type":"doi","id":"10.21203\/rs.3.rs-235968\/v2","asserted-by":"object"},{"id-type":"doi","id":"10.21203\/rs.3.rs-235968\/v1","asserted-by":"object"}]},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,19]]},"assertion":[{"value":"12 August 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 March 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study complied with the \u201cGuiding principles for the care and use of laboratory animals\u201d of The Japanese Pharmacological Society and was approved by the Experimental Animal Research Committee of St. Marianna University Graduate School of Medicine (approval number: 2002008).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}}]}}