{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T16:31:10Z","timestamp":1789576270886,"version":"build-2803163510"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2022,5,11]],"date-time":"2022-05-11T00:00:00Z","timestamp":1652227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,5,11]],"date-time":"2022-05-11T00:00:00Z","timestamp":1652227200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Hunan Forestry Science and Technology Innovation Plan Project","award":["XLK202106-2"],"award-info":[{"award-number":["XLK202106-2"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1007\/s11033-022-07492-0","type":"journal-article","created":{"date-parts":[[2022,5,11]],"date-time":"2022-05-11T15:05:18Z","timestamp":1652281518000},"page":"5585-5593","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Comparative transcriptome analysis of leaf, stem, and root tissues of Semiliquidambar cathayensis reveals candidate genes involved in terpenoid biosynthesis"],"prefix":"10.1007","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5591-182X","authenticated-orcid":false,"given":"Xiaoming","family":"Tian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lihong","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyuan","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangfeng","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaofei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,5,11]]},"reference":[{"key":"7492_CR1","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.13592\/j.cnki.ppj.2020.0558","volume":"57","author":"XM Tian","year":"2021","unstructured":"Tian XM, Yan LH, Jiang L et al (2021) Chemical comparison of different tissues of Semiliquidambar cathayensis Chang by UHPLC-QTOF\/MS\u2013based metabonomics. Plant Physiol J 57:1311\u20131318. https:\/\/doi.org\/10.13592\/j.cnki.ppj.2020.0558","journal-title":"Plant Physiol J"},{"key":"7492_CR2","unstructured":"Yang WL, Yao ZS, Luo XQ et al (1999) Analgesic and anti-inflammatory effects of the ethanol extracts of Jinlu Ban Fenghe (Semiliquidambar cathayensis) root. Jiangxi Sci 17:176\u2013179"},{"key":"7492_CR3","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24224098","author":"L Yang","year":"2019","unstructured":"Yang L, Liu RH, He JW (2019) Rapid analysis of the chemical compositions in Semiliquidambar cathayensis roots by ultra high-performance liquid chromatography and quadrupole time-of-flight tandem mass spectrometry. Molecules. https:\/\/doi.org\/10.3390\/molecules24224098","journal-title":"Molecules"},{"key":"7492_CR4","first-page":"2543","volume":"38","author":"HX Lu","year":"2015","unstructured":"Lu HX, Wu ZL, Liang WJ, Chen ML, Huang BB, Wei QQ (2015) Chemical constituents from Semiliquidambar cathayensis Roots. Zhong Yao Cai 38:2543\u20132546","journal-title":"Zhong Yao Cai"},{"key":"7492_CR5","unstructured":"Zhou GX, Yang YC, Shi JG, Yang WL(2002) Studies on chemical constituents from Semiliquidambar cathayensis. Chin Trad Herb Drugs 07:16\u201318"},{"key":"7492_CR6","doi-asserted-by":"publisher","DOI":"10.1002\/pld3.305","volume":"5","author":"SK Singh","year":"2021","unstructured":"Singh SK, Patra B, Paul P, Liu Y, Pattanaik S, Yuan L (2021) BHLH iridoid SYNTHESIS 3 is a member of a bHLH gene cluster regulating terpenoid indole alkaloid biosynthesis in Catharanthus roseus. Plant Direct 5:e00305. https:\/\/doi.org\/10.1002\/pld3.305","journal-title":"Plant Direct"},{"key":"7492_CR7","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.3389\/fpls.2016.01203","volume":"7","author":"N Cherukupalli","year":"2016","unstructured":"Cherukupalli N, Divate M, Mittapelli SR, Khareedu VR, Vudem DR (2016) De novo assembly of leaf transcriptome in the medicinal plant Andrographis paniculata. Front Plant Sci 7:1203. https:\/\/doi.org\/10.3389\/fpls.2016.01203","journal-title":"Front Plant Sci"},{"key":"7492_CR8","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1007\/s10725-016-0207-6","volume":"81","author":"SRD Balusamy","year":"2017","unstructured":"Balusamy SRD, Rahimi S, Cho YG, Senthil K, Yang DC (2017) Overexpression of geraniol 10-hydroxylase from panax ginseng conferred enhanced resistance to Pseudomonas syringae in Arabidopsis. Plant Growth Regul 81:305\u2013316","journal-title":"Plant Growth Regul"},{"key":"7492_CR9","doi-asserted-by":"publisher","first-page":"627","DOI":"10.3389\/fpls.2017.00627","volume":"8","author":"X Fang","year":"2017","unstructured":"Fang X, Li CY, Yang Y, Cui MY, Chen XY, Yang L (2017) Identification of a novel (-)-5-Epieremophilene synthase from Salvia miltiorrhiza via transcriptome mining. Front Plant Sci 8:627. https:\/\/doi.org\/10.3389\/fpls.2017.00627","journal-title":"Front Plant Sci"},{"key":"7492_CR10","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1007\/s13205-020-02263-9","volume":"10","author":"B Karpaga Raja Sundari","year":"2020","unstructured":"Karpaga Raja Sundari B, Budhwar R, Dwarakanath BS, Thyagarajan SP (2020) De novo transcriptome analysis unravels tissue-specific expression of candidate genes involved in major secondary metabolite biosynthetic pathways of Plumbago zeylanica: implication for pharmacological potential. 3 Biotech 10:271. https:\/\/doi.org\/10.1007\/s13205-020-02263-9","journal-title":"3 Biotech"},{"key":"7492_CR11","doi-asserted-by":"publisher","first-page":"9990910","DOI":"10.1155\/2021\/9990910","volume":"2021","author":"Y Xu","year":"2021","unstructured":"Xu Y, Tian S, Li R, Huang X, Li F, Ge F et al (2021) Transcriptome characterization and identification of molecular markers (SNP, SSR, and indels) in the medicinal plant Sarcandra glabra spp. BioMed Res Int 2021:9990910. https:\/\/doi.org\/10.1155\/2021\/9990910","journal-title":"BioMed Res Int"},{"key":"7492_CR12","doi-asserted-by":"publisher","first-page":"1979","DOI":"10.1007\/s11033-020-05294-w","volume":"47","author":"CF Jin","year":"2020","unstructured":"Jin CF, Li ZQ, Li Y, Wang S, Li L, Liu M et al (2020) Transcriptome analysis of terpenoid biosynthetic genes and simple sequence repeat marker screening in Eucommia ulmoides. Mol Biol Rep 47:1979\u20131990. https:\/\/doi.org\/10.1007\/s11033-020-05294-w","journal-title":"Mol Biol Rep"},{"key":"7492_CR13","first-page":"247","volume":"29","author":"XD Shi","year":"2018","unstructured":"Shi XD, Gu YX, Dai J et al (2018) Analysis of secondary metabolism pathway genes based on Magnolia officinalis transcriptome. Lishizhen Med Mater Med Res 29:247\u2013250","journal-title":"Lishizhen Med Mater Med Res"},{"key":"7492_CR14","unstructured":"Yang JRNA. Seq for DEG analysis About triterpenoid saponin synthesis and transcript profiling of Ardisia crenata Sims. Master\u2019s Degree Sichuan Agric Univ Sichuan Prov China. 2015."},{"key":"7492_CR15","doi-asserted-by":"publisher","first-page":"293","DOI":"10.18474\/JES18-103","volume":"54","author":"J Cheng","year":"2019","unstructured":"Cheng J, Lyu Zh, Wang C, Chen J, Lin T (2019) De novo analysis of Heortia Vitessoides (Lepidoptera: Crambidae) transcriptome and identification of putative cytochrome P450 monooxygenase genes. J Entomol Sci 54:293\u2013315. https:\/\/doi.org\/10.18474\/JES18-103","journal-title":"J Entomol Sci"},{"key":"7492_CR16","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1007\/s11105-019-01165-2","volume":"37","author":"YL Liu","year":"2019","unstructured":"Liu YL, Geng YP, Song ML, Zhang P, Hou J, Wang W (2019) Genetic structure and diversity of Glycyrrhiza populations based on transcriptome SSR markers. Plant Mol Biol Report 37:401\u2013412. https:\/\/doi.org\/10.1007\/s11105-019-01165-2","journal-title":"Plant Mol Biol Report"},{"key":"7492_CR17","first-page":"901","volume":"37","author":"LL Guan","year":"2016","unstructured":"Guan LL, Xia QF, Shi XB et al (2016) Cloning and analysis of geranyl pyrophosphate synthase (GPPS) sequence of Blumea balsamifera L. DC on transcriptome information. Chin J Trop Crops 37:901\u20139","journal-title":"Chin J Trop Crops"},{"key":"7492_CR18","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1111\/ppl.12213","volume":"152","author":"S Singh","year":"2014","unstructured":"Singh S, Pal S, Shanker K, Chanotiya CS, Gupta MM, Dwivedi UN et al (2014) Sterol partitioning by HMGR and DXR for routing intermediates toward with anolide biosynthesis. Physiol Plant 152:617\u2013633. https:\/\/doi.org\/10.1111\/ppl.12213","journal-title":"Physiol Plant"},{"key":"7492_CR19","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1007\/s00425-004-1301-y","volume":"219","author":"D Manzano","year":"2004","unstructured":"Manzano D, Fern\u00e1ndez-Busquets X, Schaller H, Gonz\u00e1lez V, Boronat A, Arr\u00f3 M et al (2004) The metabolic imbalance underlying lesion formation in Arabidopsis thaliana overexpressing farnesyl diphosphate synthase (isoform 1S) leads to oxidative stress and is triggered by the developmental decline of endogenous HMGR activity. Planta 219:982\u2013992. https:\/\/doi.org\/10.1007\/s00425-004-1301-y","journal-title":"Planta"},{"key":"7492_CR20","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2021.147454","volume":"787","author":"WZ Yang","year":"2021","unstructured":"Yang WZ, Cao J, Wu Y, Kong F, Li L (2021) Review on plant terpenoid emissions worldwide and in China. Sci Total Environ 787:147454. https:\/\/doi.org\/10.1016\/j.scitotenv.2021.147454","journal-title":"Sci Total Environ"},{"key":"7492_CR21","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.scienta.2016.12.025","volume":"216","author":"C Zhou","year":"2017","unstructured":"Zhou C, Guan YD (2017) The molecular basis of superficial scald development related to ethylene perception and alpha-farnesene metabolism in \u201cwujiuxiang\u201d pear. Hortic Amst 216:76\u201382","journal-title":"Hortic Amst"},{"key":"7492_CR22","volume-title":"Study on molecular structure, biochemical characterization and expression of squalene synthase from Siraitia grosvenorii","author":"HL Su","year":"2017","unstructured":"Su HL (2017) Study on molecular structure, biochemical characterization and expression of squalene synthase from Siraitia grosvenorii. Doct. Degree Guangxi Med. Univ. Guangxi Prov, China"},{"key":"7492_CR23","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.3389\/fpls.2016.01274","volume":"7","author":"Q Rong","year":"2016","unstructured":"Rong Q, Jiang D, Chen Y, Shen Y, Yuan Q, Lin H et al (2016) Molecular cloning and functional analysis of squalene synthase 2(SQS2) in Salvia miltiorrhiza Bunge. Front Plant Sci 7:1274. https:\/\/doi.org\/10.3389\/fpls.2016.01274","journal-title":"Front Plant Sci"},{"key":"7492_CR24","first-page":"1090","volume":"35","author":"HH Li","year":"2014","unstructured":"Li HH, Liu XY, Wang W et al (2014) Cloning and sequence analysis of squalene synthase gene in Eriobotrya japonica L. Chin J Trop Crops 35:1090\u20131094","journal-title":"Chin J Trop Crops"},{"key":"7492_CR25","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1093\/pcp\/pcq179","volume":"52","author":"TD Kim","year":"2011","unstructured":"Kim TD, Han JY, Huh GH, Choi YE (2011) Expression and functional characterization of three squalene synthase genes associated with saponin biosynthesis in panax ginseng. Plant Cell Physiol 52:125\u2013137. https:\/\/doi.org\/10.1093\/pcp\/pcq179","journal-title":"Plant Cell Physiol"},{"key":"7492_CR26","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1007\/s11103-012-9923-0","volume":"79","author":"G Guirimand","year":"2012","unstructured":"Guirimand G, Guihur A, Phillips MA, Oudin A, Gl\u00e9varec G, Melin C et al (2012) A single gene encodes isopentenyl diphosphate isomerase isoforms targeted to plastids, mitochondria and peroxisomes in Catharanthus roseus. Plant Mol Biol 79:443\u2013459. https:\/\/doi.org\/10.1007\/s11103-012-9923-0","journal-title":"Plant Mol Biol"},{"key":"7492_CR27","doi-asserted-by":"publisher","first-page":"20206","DOI":"10.3390\/molecules201119689","volume":"20","author":"XN Zhang","year":"2015","unstructured":"Zhang XN, Guan HY, Dai ZB, Guo J, Shen Y, Cui G et al (2015) Functional analysis of the isopentenyl diphosphate isomerase of Salvia miltiorrhiza via color complementation and RNA interference. Molecules 20:20206\u201320218. https:\/\/doi.org\/10.3390\/molecules201119689","journal-title":"Molecules"},{"key":"7492_CR28","first-page":"45","volume":"23","author":"DY Zhang","year":"2017","unstructured":"Zhang DY, Wen H, Wang W et al (2017) Transcriptional analysis of terpenoid biosynthesis in Aconitum Carmichaelii. Chin J Exp Trad Med Formulae 23:45\u201350","journal-title":"Chin J Exp Trad Med Formulae"},{"key":"7492_CR29","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1046\/j.1365-313x.2000.00875.x","volume":"24","author":"F Bouvier","year":"2000","unstructured":"Bouvier F, Suire C, d\u2019Harlingue A, Backhaus RA, Camara B (2000) Molecular cloning of geranyl diphosphate synthase and compartmentation of monoterpene synthesis in plant cells. Plant J 24:241\u2013252. https:\/\/doi.org\/10.1046\/j.1365-313x.2000.00875.x","journal-title":"Plant J"},{"issue":"6","key":"7492_CR30","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/S0273-1223(99)00557-0","volume":"40","author":"E Oikawa","year":"1999","unstructured":"Oikawa E, Ishibashi Y (1999) Activity of geranyl pyrophosphate synthase in musty odor producing cyanobacteria. Water Sci Technol 40(6):195\u2013202. https:\/\/doi.org\/10.1016\/S0273-1223(99)00557-0","journal-title":"Water Sci Technol"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-022-07492-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11033-022-07492-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-022-07492-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T23:01:44Z","timestamp":1657234904000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11033-022-07492-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,11]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["7492"],"URL":"https:\/\/doi.org\/10.1007\/s11033-022-07492-0","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,11]]},"assertion":[{"value":"11 January 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 April 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 May 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}