{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T01:47:34Z","timestamp":1767836854773,"version":"3.49.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T00:00:00Z","timestamp":1655424000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T00:00:00Z","timestamp":1655424000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100008789","name":"Department of Science and Technology, Government of West Bengal","doi-asserted-by":"publisher","award":["793(Sanc.)\/ST\/P\/S&T\/1G-2\/2016, Dt. 06\/12\/2016"],"award-info":[{"award-number":["793(Sanc.)\/ST\/P\/S&T\/1G-2\/2016, Dt. 06\/12\/2016"]}],"id":[{"id":"10.13039\/501100008789","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1007\/s11033-022-07653-1","type":"journal-article","created":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T09:10:07Z","timestamp":1655457007000},"page":"8369-8380","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of hyperglycemia on the expression of GLUT1 during oral carcinogenesis in rats"],"prefix":"10.1007","volume":"49","author":[{"given":"Subhamita","family":"Dalal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jayashree","family":"Adhikary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anup","family":"Roy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shampa Sarkar","family":"Biswas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prabir Kumar","family":"Mukhopadhyay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sagar","family":"Acharya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9334-5152","authenticated-orcid":false,"given":"Amlan","family":"Ghosh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,6,17]]},"reference":[{"issue":"5","key":"7653_CR1","first-page":"e586","volume":"22","author":"E Mauri-Obradors","year":"2017","unstructured":"Mauri-Obradors E, Estrugo-Devesa A, Jan\u00e9-Salas E, Vi\u00f1as M, L\u00f3pez-L\u00f3pez J (2017) Oral manifestations of diabetes mellitus. A systematic review. Med Oral Patol Oral Cir Bucal 22(5):e586\u2013e594","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"7653_CR2","doi-asserted-by":"publisher","first-page":"7848735","DOI":"10.1155\/2018\/7848735","volume":"2018","author":"G Cervino","year":"2018","unstructured":"Cervino G, Fiorillo L, Laino L, Herford AS, Lauritano F, Giudice GL, Fam\u00e0 F, Santoro R, Troiano G, Iannello G, Cicci\u00f9 M (2018) Oral health impact profile in celiac patients: analysis of recent findings in a literature review. Gastroenterol Res Pract 2018:7848735","journal-title":"Gastroenterol Res Pract"},{"issue":"8","key":"7653_CR3","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1007\/s11892-014-0517-x","volume":"14","author":"A Cohn","year":"2014","unstructured":"Cohn A, Sofia AM, Kupfer SS (2014) Type 1 diabetes and celiac disease: clinical overlap and new insights into disease pathogenesis. Curr Diab Rep 14(8):517","journal-title":"Curr Diab Rep"},{"issue":"3","key":"7653_CR4","first-page":"ZC12","volume":"10","author":"C Seethalakshmi","year":"2016","unstructured":"Seethalakshmi C, Reddy RC, Asifa N, Prabhu S (2016) Correlation of salivary pH, incidence of dental caries and periodontal status in diabetes mellitus patients: a cross-sectional study. J Clin Diagn Res 10(3):ZC12\u2013ZC14","journal-title":"J Clin Diagn Res"},{"issue":"4","key":"7653_CR5","doi-asserted-by":"publisher","first-page":"199","DOI":"10.2337\/diaspect.24.4.199","volume":"24","author":"BK Gandara","year":"2011","unstructured":"Gandara BK, Morton TH (2011) Non-periodontal oral manifestations of diabetes: a framework for medical care providers. Diabetes Spectr 24(4):199\u2013205","journal-title":"Diabetes Spectr"},{"key":"7653_CR6","doi-asserted-by":"publisher","first-page":"5907195","DOI":"10.1155\/2019\/5907195","volume":"2019","author":"G Cervino","year":"2019","unstructured":"Cervino G, Terranova A, Briguglio F, De Stefano R, Fam\u00e0 F, D\u2019Amico C, Amoroso G, Marino S, Gorassini F, Mastroieni R, Scoglio C, Catalano F, Lauritano F, Matarese M, Lo Giudice R, Nastro Siniscalchi E, Fiorillo L (2019) Diabetes: oral health related quality of life and oral alterations. Biomed Res Int 2019:5907195","journal-title":"Biomed Res Int"},{"issue":"2","key":"7653_CR7","first-page":"179","volume":"11","author":"AY Al-Maskari","year":"2011","unstructured":"Al-Maskari AY, Al-Maskari MY, Al-Sudairy S (2011) Oral manifestations and complications of diabetes mellitus: a review. Sultan Qaboos Univ Med J 11(2):179\u2013186","journal-title":"Sultan Qaboos Univ Med J"},{"issue":"2","key":"7653_CR8","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1002\/ijc.21345","volume":"118","author":"RP Dikshit","year":"2006","unstructured":"Dikshit RP, Ramadas K, Hashibe M, Thomas G, Somanathan T, Sankaranarayanan R (2006) Association between diabetes mellitus and pre-malignant oral diseases: a cross sectional study in Kerala, India. Int J Cancer 118(2):453\u2013457","journal-title":"Int J Cancer"},{"issue":"3","key":"7653_CR9","doi-asserted-by":"publisher","first-page":"770","DOI":"10.2337\/diacare.27.3.770","volume":"27","author":"M Ujp\u00e1l","year":"2004","unstructured":"Ujp\u00e1l M, Matos O, B\u00edbok G, Somogyi A, Szab\u00f3 G, Suba Z (2004) Diabetes and oral tumors in Hungary: epidemiological correlations. Diabetes Care 27(3):770\u2013774","journal-title":"Diabetes Care"},{"issue":"3","key":"7653_CR10","first-page":"381","volume":"9","author":"R Basu","year":"2008","unstructured":"Basu R, Mandal S, Ghosh A, Poddar TK (2008) Role of tobacco in the development of head and neck squamous cell carcinoma in an eastern Indian population. Asian Pac J Cancer Prev 9(3):381\u2013386","journal-title":"Asian Pac J Cancer Prev"},{"key":"7653_CR11","first-page":"29","volume":"12","author":"X Jiang","year":"2019","unstructured":"Jiang X, Wu J, Wang J, Huang R (2019) Tobacco and oral squamous cell carcinoma: a review of carcinogenic pathways. Tob Induc Dis 12:29","journal-title":"Tob Induc Dis"},{"issue":"3B","key":"7653_CR12","first-page":"1465","volume":"27","author":"E Vairaktaris","year":"2007","unstructured":"Vairaktaris E, Kalokerinos G, Goutzanis L, Spyridonidou S, Vassiliou S, Derka S, Nkenke E, Yapijakis C, Vylliotis A, Lazaris A, Patsouris E (2007) Diabetes alters expression of p53 and c-myc in different stages of oral oncogenesis. Anticancer Res 27(3B):1465\u20131473","journal-title":"Anticancer Res"},{"issue":"2","key":"7653_CR13","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.oraloncology.2006.02.004","volume":"43","author":"L Goutzanis","year":"2007","unstructured":"Goutzanis L, Vairaktaris E, Yapijakis C, Kavantzas N, Nkenke E, Derka S, Vassiliou S, Acil Y, Kessler P, Stavrianeas N, Perrea D, Donta I, Skandalakis P, Patsouris E (2007) Diabetes may increase risk for oral cancer through the insulin receptor substrate-1 and focal adhesion kinase pathway. Oral Oncol 43(2):165\u2013173","journal-title":"Oral Oncol"},{"issue":"6","key":"7653_CR14","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1016\/j.ccr.2006.04.023","volume":"9","author":"VR Fantin","year":"2006","unstructured":"Fantin VR, St-Pierre J, Leder P (2006) Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. Cancer Cell 9(6):425\u2013434","journal-title":"Cancer Cell"},{"issue":"1","key":"7653_CR15","doi-asserted-by":"publisher","first-page":"R51","DOI":"10.1530\/JME-13-0152","volume":"52","author":"C Garc\u00eda-Jim\u00e9nez","year":"2013","unstructured":"Garc\u00eda-Jim\u00e9nez C, Garc\u00eda-Mart\u00ednez JM, Chocarro-Calvo A, De la Vieja A (2013) A new link between diabetes and cancer: enhanced WNT\/\u03b2-catenin signaling by high glucose. J Mol Endocrinol 52(1):R51-66","journal-title":"J Mol Endocrinol"},{"key":"7653_CR16","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1079\/BJN2002763","volume":"89","author":"IS Wood","year":"2003","unstructured":"Wood IS, Trayhurn P (2003) Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins. Br J Nutr 89:3\u20139","journal-title":"Br J Nutr"},{"issue":"3","key":"7653_CR17","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1002\/jcp.20166","volume":"202","author":"ML Macheda","year":"2005","unstructured":"Macheda ML, Rogers S, Best JD (2005) Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer. J Cell Physiol 202(3):654\u2013662","journal-title":"J Cell Physiol"},{"issue":"2","key":"7653_CR18","doi-asserted-by":"publisher","first-page":"115","DOI":"10.2334\/josnusd.57.115","volume":"57","author":"VC Angadi","year":"2015","unstructured":"Angadi VC, Angadi PV (2015) GLUT-1 immunoexpression in oral epithelial dysplasia, oral squamous cell carcinoma, and verrucous carcinoma. J Oral Sci 57(2):115\u2013122","journal-title":"J Oral Sci"},{"issue":"1","key":"7653_CR19","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1111\/j.1600-0714.2009.00814.x","volume":"39","author":"S Ohba","year":"2010","unstructured":"Ohba S, Fujii H, Ito S, Fujimaki M, Matsumoto F, Furukawa M, Yokoyama J, Kusunoki T, Ikeda K, Hino O (2010) Overexpression of GLUT-1 in the invasion front is associated with depth of oral squamous cell carcinoma and prognosis. J Oral Pathol Med 39(1):74\u201378","journal-title":"J Oral Pathol Med"},{"issue":"2","key":"7653_CR20","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/S0304-3835(00)00613-3","volume":"161","author":"M Fukuzumi","year":"2000","unstructured":"Fukuzumi M, Hamakawa H, Onishi A, Sumida T, Tanioka H (2000) Gene expression of GLUT isoforms and VHL in oral squamous cell carcinoma. Cancer Lett 161(2):133\u2013140","journal-title":"Cancer Lett"},{"issue":"5","key":"7653_CR21","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1590\/0103-6440201300054","volume":"25","author":"CF Demeda","year":"2014","unstructured":"Demeda CF, Carvalho CH, Aquino AR, Nonaka CF, Souza LB, Pinto LP (2014) Expression of glucose transporters 1 and 3 in metastatic and non-metastatic lower lip squamous cell carcinoma. Braz Dent J 25(5):372\u2013378","journal-title":"Braz Dent J"},{"issue":"4","key":"7653_CR22","doi-asserted-by":"publisher","first-page":"2309","DOI":"10.1007\/s13277-014-2838-4","volume":"36","author":"K Starska","year":"2015","unstructured":"Starska K, Forma E, J\u00f3\u017awiak P, Bry\u015b M, Lewy-Trenda I, Brzezi\u0144ska-B\u0142aszczyk E, Krze\u015blak A (2015) Gene and protein expression of glucose transporter 1 and glucose transporter 3 in human laryngeal cancer-the relationship with regulatory hypoxia-inducible factor-1\u03b1 expression, tumor invasiveness, and patient prognosis. Tumour Biol 36(4):2309\u20132321","journal-title":"Tumour Biol"},{"issue":"7","key":"7653_CR23","first-page":"1779","volume":"19","author":"SG Feitosa","year":"2018","unstructured":"Feitosa SG, Viana KF, Luna ECM, Costa FWG, Cavalcante RB, Chaves FN, Chaves HV, Pereira KMA (2018) Immunohistochemical evaluation of GLUT-3 and GLUT-4 in oral epithelial dysplasia and oral squamous cell carcinoma. Asian Pac J Cancer Prev 19(7):1779\u20131783","journal-title":"Asian Pac J Cancer Prev"},{"issue":"7","key":"7653_CR24","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1016\/j.oraloncology.2005.10.013","volume":"42","author":"D Kanojia","year":"2006","unstructured":"Kanojia D, Vaidya MM (2006) 4-Nitroquinoline-1-oxide induced experimental oral carcinogenesis. Oral Oncol 42(7):655\u2013667","journal-title":"Oral Oncol"},{"issue":"3","key":"7653_CR25","doi-asserted-by":"publisher","first-page":"168","DOI":"10.5455\/medarh.2020.74.168-171","volume":"74","author":"KF Amawi","year":"2020","unstructured":"Amawi KF, Alkhatib AJ (2020) Urtica pilulifera in treating pre-diabetic rat model to control the blood glucose, lipids and oxidative stress. Med Arch 74(3):168\u2013171","journal-title":"Med Arch"},{"issue":"5","key":"7653_CR26","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1016\/S1368-8375(03)00013-7","volume":"39","author":"I Tamura","year":"2003","unstructured":"Tamura I, Sakaki T, Chaqour B, Howard PS, Ikeo T, Macarak EJ (2003) Correlation of P-cadherin and beta-catenin expression and phosphorylation with carcinogenesis in rat tongue cancer induced with 4-nitroquinoline 1-oxide. Oral Oncol 39(5):506\u2013514","journal-title":"Oral Oncol"},{"issue":"1","key":"7653_CR27","doi-asserted-by":"crossref","first-page":"19","DOI":"10.4103\/jomfp.JOMFP_13_19","volume":"23","author":"K Ranganathan","year":"2019","unstructured":"Ranganathan K, Kavitha L (2019) Oral epithelial dysplasia: classifications and clinical relevance in risk assessment of oral potentially malignant disorders. J Oral Maxillofac Pathol 23(1):19\u201327","journal-title":"J Oral Maxillofac Pathol"},{"issue":"6","key":"7653_CR28","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1111\/j.1600-0714.2012.01133.x","volume":"41","author":"SM Moon","year":"2012","unstructured":"Moon SM, Ahn MY, Kwon SM, Kim SA, Ahn SG, Yoon JH (2012) Homeobox C5 expression is associated with the progression of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. J Oral Pathol Med 41(6):470\u2013476","journal-title":"J Oral Pathol Med"},{"issue":"4","key":"7653_CR29","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"KJ Livak","year":"2001","unstructured":"Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25(4):402\u2013408","journal-title":"Methods"},{"issue":"22","key":"7653_CR30","doi-asserted-by":"publisher","first-page":"6643","DOI":"10.1158\/1078-0432.CCR-06-1759","volume":"12","author":"F Perrone","year":"2006","unstructured":"Perrone F, Suardi S, Pastore E, Casieri P, Orsenigo M, Caramuta S, Dagrada G, Losa M, Licitra L, Bossi P, Staurengo S, Oggionni M, Locati L, Cantu G, Squadrelli M, Carbone A, Pierotti MA, Pilotti S (2006) Molecular and cytogenetic subgroups of oropharyngeal squamous cell carcinoma. Clin Cancer Res 12(22):6643\u20136651","journal-title":"Clin Cancer Res"},{"key":"7653_CR31","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1111\/j.1755-9294.2009.01031.x","volume":"2","author":"DA Ribeiro","year":"2009","unstructured":"Ribeiro DA, Fracalossi ACC, Gomes TS, Oshima CTF (2009) COX-2 expression during 4-nitroquinoline 1-oxide induced rat tongue carcinogenesis. Basic Appl Pathol 2:9\u201314","journal-title":"Basic Appl Pathol"},{"key":"7653_CR32","doi-asserted-by":"publisher","first-page":"2627","DOI":"10.1158\/0008-5472.CAN-03-0846","volume":"64","author":"F Schwartzenberg-Bar-Yoseph","year":"2004","unstructured":"Schwartzenberg-Bar-Yoseph F, Armoni M, Karnieli E (2004) The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression. Cancer Res 64:2627\u20132633","journal-title":"Cancer Res"},{"issue":"4","key":"7653_CR33","first-page":"417","volume":"190","author":"SA Shahnavaz","year":"2000","unstructured":"Shahnavaz SA, Regezi JA, Bradley G, Dub\u00e9 ID, Jordan RC (2000) p53 gene mutations in sequential oral epithelial dysplasias and squamous cell carcinomas. J Athol 190(4):417\u2013422","journal-title":"J Athol"},{"issue":"5","key":"7653_CR34","doi-asserted-by":"publisher","first-page":"L738","DOI":"10.1152\/ajplung.00375.2002","volume":"284","author":"G Wang","year":"2003","unstructured":"Wang G, Guo X, Floros J (2003) Human SP-A 3\u2032-UTR variants mediate differential gene expression in basal levels and in response to dexamethasone. Am J Physiol Lung Cell Mol Physiol 284(5):L738-748","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"5","key":"7653_CR35","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1016\/j.bbadis.2015.02.009","volume":"1852","author":"GP Maiti","year":"2015","unstructured":"Maiti GP, Ghosh A, Mondal P, Baral A, Datta S, Samadder S, Nayak SP, Chakrabarti J, Biswas J, Sikdar N, Chowdhury S, Roy B, Roychowdhury S, Panda CK (2015) SNP rs1049430 in the 3\u2032-UTR of SH3GL2 regulates its expression: clinical and prognostic implications in head and neck squamous cell carcinoma. Biochim Biophys Acta 1852(5):1059\u20131067","journal-title":"Biochim Biophys Acta"},{"issue":"1","key":"7653_CR36","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1186\/s12576-020-00773-y","volume":"22","author":"AA Mamun","year":"2020","unstructured":"Mamun AA, Hayashi H, Yamamura A, Nayeem MJ, Sato M (2020) Hypoxia induces the translocation of glucose transporter 1 to the plasma membrane in vascular endothelial cells. J Physiol Sci 22(1):44","journal-title":"J Physiol Sci"},{"issue":"4","key":"7653_CR37","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1111\/jop.12488","volume":"46","author":"O Kujan","year":"2017","unstructured":"Kujan O, Shearston K, Farah CS (2017) The role of hypoxia in oral cancer and potentially malignant disorders: a review. J Oral Pathol Med 46(4):246\u2013252","journal-title":"J Oral Pathol Med"},{"issue":"2","key":"7653_CR38","doi-asserted-by":"publisher","first-page":"913","DOI":"10.3892\/or.2014.3673","volume":"33","author":"P J\u00f3\u017awiak","year":"2015","unstructured":"J\u00f3\u017awiak P, Krze\u015blak A, Bry\u015b M, Lipi\u0144ska A (2015) Glucose-dependent glucose transporter 1 expression and its impact on viability of thyroid cancer cells. Oncol Rep 33(2):913\u2013920","journal-title":"Oncol Rep"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-022-07653-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11033-022-07653-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-022-07653-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T09:45:37Z","timestamp":1700732737000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11033-022-07653-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,17]]},"references-count":38,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["7653"],"URL":"https:\/\/doi.org\/10.1007\/s11033-022-07653-1","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,17]]},"assertion":[{"value":"10 January 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 June 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None of the authors declared any conflict of interest relevant to the content of this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was approved by the Institutional Animal Ethical Committee of Presidency University registered under Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA), India.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}}]}}