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All the tissues used for research purpose was obtained following informed consent, from Tumor bank, Department of Oncopathology, Cancer Institute (WIA). Animal studies were carried out with prior approval from the Institutional Animal Ethics Committee (IAEC) of Cancer Institute (W.I.A), Adyar, Chennai, India with IAEC approval number: CIWIA0119WR. Care of animals complied according to CPCSEA (Committee for the purpose of Control and Supervision of Experiments on Animals) guidelines, Government of India.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}