{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T09:11:56Z","timestamp":1781946716444,"version":"3.54.5"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2022,10,10]],"date-time":"2022-10-10T00:00:00Z","timestamp":1665360000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,10,10]],"date-time":"2022-10-10T00:00:00Z","timestamp":1665360000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1007\/s11033-022-07946-5","type":"journal-article","created":{"date-parts":[[2022,10,10]],"date-time":"2022-10-10T12:57:20Z","timestamp":1665406640000},"page":"11829-11846","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Isolation and genetic analysis of Porcine circovirus 2 in southern India evidences high circulation of Porcine circovirus 2d genotype"],"prefix":"10.1007","volume":"49","author":[{"given":"S.","family":"Parthiban","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9852-4245","authenticated-orcid":false,"given":"A.","family":"Ramesh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anbu Kumar","family":"Karuppannan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Dhinakar Raj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Hemalatha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Parthiban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Senthilkumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Balasubramaniyam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Sumanth Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Ranganatha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chintu","family":"Ravishankar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,10,10]]},"reference":[{"issue":"1","key":"7946_CR1","doi-asserted-by":"publisher","first-page":"17747","DOI":"10.1038\/s41598-020-74627-3","volume":"10","author":"F Correa-Fiz","year":"2020","unstructured":"Correa-Fiz F, Franzo G, Llorens A, Huerta E, Sibila M, Kekarainen T, Segal\u00e9s J (2020) Porcine circovirus 2 (PCV2) population study in experimentally infected pigs developing PCV2-systemic disease or a subclinical infection. Sci Rep 10(1):17747. https:\/\/doi.org\/10.1038\/s41598-020-74627-3","journal-title":"Sci Rep"},{"issue":"9","key":"7946_CR2","doi-asserted-by":"publisher","first-page":"1676","DOI":"10.3390\/v13091676","volume":"13","author":"A Rakibuzzaman","year":"2021","unstructured":"Rakibuzzaman A, Pi\u00f1eyro P, Pillatzki A, Ramamoorthy S (2021) Harnessing the genetic plasticity of Porcine Circovirus type 2 to target suicidal replication. Viruses 13(9):1676. https:\/\/doi.org\/10.3390\/v13091676","journal-title":"Viruses"},{"key":"7946_CR3","doi-asserted-by":"publisher","DOI":"10.1186\/s13567-022-01029-w","author":"M Bandrick","year":"2022","unstructured":"Bandrick M, Balasch M, Heinz A, Taylor L, King V, Toepfer J, Foss D (2022) A bivalent porcine circovirus type 2 (PCV2), PCV2a-PCV2b, vaccine offers biologically superior protection compared to monovalent PCV2 vaccines. Vet Res. https:\/\/doi.org\/10.1186\/s13567-022-01029-w","journal-title":"Vet Res"},{"key":"7946_CR4","doi-asserted-by":"publisher","first-page":"198044","DOI":"10.1016\/j.virusres.2020.198044","volume":"286","author":"T Opriessnig","year":"2020","unstructured":"Opriessnig T, Karuppannan AK, Castro AMMG, Xiao CT (2020) Porcine circoviruses: current status, knowledge gaps and challenges. Virus Res 286:198044","journal-title":"Virus Res"},{"issue":"7","key":"7946_CR5","doi-asserted-by":"publisher","first-page":"2494","DOI":"10.1128\/JCM.38.7.2494-2503.2000","volume":"38","author":"M Fenaux","year":"2000","unstructured":"Fenaux M, Halbur PG, Gill M, Toth TE, Meng XJ (2000) Genetic characterization of type 2 porcine circovirus (PCV-2) from pigs with postweaning multisystemic wasting syndrome in different geographic regions of North America and development of a differential PCR-restriction fragment length polymorphism assay to detect and differentiate between infections with PCV-1 and PCV-2. J Clin Microbiol 38(7):2494\u20132503","journal-title":"J Clin Microbiol"},{"issue":"2","key":"7946_CR6","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.virol.2006.07.047","volume":"357","author":"A Olvera","year":"2007","unstructured":"Olvera A, Cortey M, Segal\u00e9s J (2007) Molecular evolution of porcine circovirus type 2 genomes: phylogeny and clonality. Virology 357(2):175\u2013185. https:\/\/doi.org\/10.1016\/j.virol.2006.07.047","journal-title":"Virology"},{"key":"7946_CR7","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.ympev.2016.04.028","volume":"100","author":"G Franzo","year":"2016","unstructured":"Franzo G, Cortey M, Segal\u00e9s J, Hughes J, Drigo M (2016) Phylodynamic analysis of porcine circovirus type 2 reveals global waves of emerging genotypes and the circulation of recombinant forms. Mol Phylogenet Evol 100:269\u2013280","journal-title":"Mol Phylogenet Evol"},{"issue":"12","key":"7946_CR8","doi-asserted-by":"publisher","first-page":"e0208585","DOI":"10.1371\/journal.pone.0208585","volume":"13","author":"G Franzo","year":"2018","unstructured":"Franzo G, Segal\u00e9s J (2018) Porcine circovirus 2 (PCV-2) genotype update and proposal of a new genotyping methodology. PLoS ONE 13(12):e0208585. https:\/\/doi.org\/10.1371\/journal.pone.0208585","journal-title":"PLoS ONE"},{"issue":"2","key":"7946_CR9","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1111\/tbed.12721","volume":"65","author":"F Bao","year":"2017","unstructured":"Bao F, Mi S, Luo Q, Guo H, Tu C, Zhu G, Gong W (2017) Retrospective study of porcine circovirus type 2 infection reveals a novel genotype PCV2f. Transbound Emerg Dis 65(2):432\u2013440","journal-title":"Transbound Emerg Dis"},{"key":"7946_CR10","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.meegid.2015.01.006","volume":"31","author":"R Anoopraj","year":"2015","unstructured":"Anoopraj R, Rajkhowa TK, Cherian S, Arya RS, Tomar N, Gupta A, Ray PK, Somvanshi R, Saikumar G (2015) Genetic characterization and phylogenetic analysis of PCV2 isolates from India: indications for emergence of natural inter-genotypic recombinants. Infect Genet Evol 31:25\u201332. https:\/\/doi.org\/10.1016\/j.meegid.2015.01.006","journal-title":"Infect Genet Evol"},{"issue":"7","key":"7946_CR11","doi-asserted-by":"publisher","first-page":"1830","DOI":"10.1099\/vir.0.000100","volume":"96","author":"CT Xiao","year":"2015","unstructured":"Xiao CT, Halbur PG, Opriessnig T (2015) Global molecular genetic analysis of porcine circovirus type 2 (PCV2) sequences confirms the presence of four main PCV2 genotypes and reveals a rapid increase of PCV2d. J Gen Virol 96(7):1830\u20131841. https:\/\/doi.org\/10.1099\/vir.0.000100","journal-title":"J Gen Virol"},{"key":"7946_CR12","unstructured":"Kumar GS, Sharma R, Paliwal OP (2006) Occurrence and pathology of postweaning multisystemic wasting syndrome. In: Compendium of invited papers and abstracts of XXIII annual conference of Indian Association of Veterinary Pathologists"},{"issue":"3","key":"7946_CR13","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1111\/tbed.12276","volume":"63","author":"AK Karuppannan","year":"2016","unstructured":"Karuppannan AK, Ramesh A, Reddy YK, Ramesh S, Mahaprabhu R, Jaisree S, Roy P, Sridhar R, Pazhanivel N, Sakthivelan SM, Sreekumar C, Murugan M, Jaishankar S, Gopi H, Purushothaman V, Kumanan K, Babu M (2016) Emergence of Porcine Circovirus 2 associated reproductive failure in southern india. Transbound Emerg Dis 63(3):314\u2013320. https:\/\/doi.org\/10.1111\/tbed.12276","journal-title":"Transbound Emerg Dis"},{"issue":"6","key":"7946_CR14","doi-asserted-by":"publisher","first-page":"1959","DOI":"10.1111\/tbed.12977","volume":"65","author":"NN Barman","year":"2018","unstructured":"Barman NN, Nath B, Kumar V, Sen A, Dutta TK, Dutta B, Rahman T, Kumar S (2018) The emergence of porcine circovirus 2 infections in the northeastern part of India: a retrospective study from 2011 to 2017. Transbound Emerg Dis 65(6):1959\u20131967. https:\/\/doi.org\/10.1111\/tbed.12977","journal-title":"Transbound Emerg Dis"},{"key":"7946_CR15","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.meegid.2019.02.026","volume":"71","author":"P Mukherjee","year":"2019","unstructured":"Mukherjee P, Karam A, Chakraborty AK, Baruah S, Pegu R, Das S, Milton AAP, Puro K, Sanjukta R, Ghatak S, Shakuntala I, Laha RG, Sen A (2019) Identification of a novel cluster of PCV2 isolates from Meghalaya, India indicates possible recombination along with changes in capsid protein. Infect Genet Evol 71:7\u201315. https:\/\/doi.org\/10.1016\/j.meegid.2019.02.026","journal-title":"Infect Genet Evol"},{"key":"7946_CR16","doi-asserted-by":"publisher","first-page":"105100","DOI":"10.1016\/j.meegid.2021.105100","volume":"96","author":"U Bhattacharjee","year":"2021","unstructured":"Bhattacharjee U, Sen A, Sharma I (2021) A retrospective study reveals the Porcine circovirus-2f genotype predominant in the indigenous pig population of North-eastern India. Infect Genet Evol 96:105100. https:\/\/doi.org\/10.1016\/j.meegid.2021.105100","journal-title":"Infect Genet Evol"},{"key":"7946_CR17","doi-asserted-by":"publisher","first-page":"104775","DOI":"10.1016\/j.meegid.2021.104775","volume":"90","author":"TK Rajkhowa","year":"2021","unstructured":"Rajkhowa TK, Lalnunthanga P, Rao PL, Subbiah M, Lalrohlua B (2021) Emergence of porcine circovirus 2g (PCV2g) and evidence for recombination between genotypes 2g, 2b and 2d among field isolates from non-vaccinated pigs in Mizoram India. Infect Genet Evol 90:104775","journal-title":"Infect Genet Evol"},{"key":"7946_CR18","doi-asserted-by":"publisher","DOI":"10.1080\/10495398.2021.1955700","author":"AL D'silva","year":"2021","unstructured":"D\u2019silva AL, Bharali A, Buragohain L, Pathak DC, Ramamurthy N, Batheja R, Mariappan AK, Gogoi SM, Barman NN, Dey S, Chellappa MM (2021) Molecular characterization of porcine circovirus 2 circulating in Assam and Arunachal Pradesh of India. Anim Biotechnol. https:\/\/doi.org\/10.1080\/10495398.2021.1955700","journal-title":"Anim Biotechnol"},{"issue":"2","key":"7946_CR19","first-page":"137","volume":"9","author":"R Sairam","year":"2019","unstructured":"Sairam R, Dhanush Krishna B, Krithiga K, Sajitha IS, Priya PM, Chintu R, Abraham MJ (2019) Molecular and pathological studies of post-weaningmulti-systemic wasting syndrome among piglets in Kerala. India Explor Anim Med Res 9(2):137\u2013144","journal-title":"India Explor Anim Med Res"},{"issue":"6","key":"7946_CR20","first-page":"485","volume":"8","author":"J Keerthana","year":"2019","unstructured":"Keerthana J, Abraham MJ, Krithiga K, Priya PM (2019) Studies on naturally infected cases of post weaning multi systemic wasting syndrome (PMWS) in piglets. Pharm Innov 8(6):485\u2013488","journal-title":"Pharm Innov"},{"issue":"1","key":"7946_CR21","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/s0166-0934(99)00032-4","volume":"80","author":"R Larochelle","year":"1999","unstructured":"Larochelle R, Antaya M, Morin M, Magar R (1999) Typing of porcine circovirus in clinical specimens by multiplex PCR. J Virol Methods 80(1):69\u201375. https:\/\/doi.org\/10.1016\/s0166-0934(99)00032-4","journal-title":"J Virol Methods"},{"key":"7946_CR22","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/j.vetmic.2017.08.006","volume":"208","author":"N Thangthamniyom","year":"2017","unstructured":"Thangthamniyom N, Sangthong P, Poolperm P, Thanantong N, Boonsoongnern A, Hansoongnern P, Semkum P, Petcharat N, Lekcharoensuk P (2017) Genetic diversity of porcine circovirus type 2 (PCV2) in Thailand during 2009\u20132015. Vet Microbiol 208:239\u2013246. https:\/\/doi.org\/10.1016\/j.vetmic.2017.08.006","journal-title":"Vet Microbiol"},{"issue":"6","key":"7946_CR23","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1093\/molbev\/msy096","volume":"35","author":"S Kumar","year":"2018","unstructured":"Kumar S, Stecher G, Li M, Knyaz C, Tamura K (2018) MEGA X: Molecular evolutionary genetics analysis across computing platforms. Mol Biol Evol 35(6):1547\u20131549. https:\/\/doi.org\/10.1093\/molbev\/msy096","journal-title":"Mol Biol Evol"},{"issue":"3","key":"7946_CR24","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1093\/oxfordjournals.molbev.a040023","volume":"10","author":"K Tamura","year":"1993","unstructured":"Tamura K, Nei M (1993) Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees. Mol Biol Evol 10(3):512\u2013526. https:\/\/doi.org\/10.1093\/oxfordjournals.molbev.a040023","journal-title":"Mol Biol Evol"},{"key":"7946_CR25","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1093\/oxfordjournals.molbev.a040454","volume":"4","author":"N Saitou","year":"1987","unstructured":"Saitou N, Nei M (1987) The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 4:406\u2013425. https:\/\/doi.org\/10.1093\/oxfordjournals.molbev.a040454","journal-title":"Mol Biol Evol"},{"issue":"1","key":"7946_CR26","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1177\/104063879801000102","volume":"10","author":"GM Allan","year":"1998","unstructured":"Allan GM, McNeilly F, Kennedy S, Daft B, Ellis JA, Haines DM, Meehan BM, Adair BM (1998) Isolation of Porcine Circovirus-like viruses from pigs with a wasting disease in the USA and Europe. J Vet Diagn Investig 10(1):3\u201310. https:\/\/doi.org\/10.1177\/104063879801000102","journal-title":"J Vet Diagn Investig"},{"issue":"1","key":"7946_CR27","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1177\/104063870001200102","volume":"12","author":"GM Allan","year":"2000","unstructured":"Allan GM, Ellis JA (2000) Porcine circoviruses: a review. J Vet Diagn Investig 12(1):3\u201314. https:\/\/doi.org\/10.1177\/104063870001200102","journal-title":"J Vet Diagn Investig"},{"issue":"4","key":"7946_CR28","first-page":"732","volume":"51","author":"SR Pegu","year":"2017","unstructured":"Pegu SR, Sarma DK, Choudhary RS, M, Sarma D, Das JP, (2017) Molecular detection of porcine circo virus type 2 and porcine parvo virus in pigs having reproductive problems and histopathological studies in the tissue of aborted pig foetuses. Indian J Anim Res 51(4):732\u2013736","journal-title":"Indian J Anim Res"},{"issue":"2","key":"7946_CR29","doi-asserted-by":"publisher","first-page":"79","DOI":"10.5958\/0973-970X.2017.00019.0","volume":"41","author":"LJ Kikon","year":"2017","unstructured":"Kikon LJ, Rajkhowa TK, Arya RS, Singh YD, Ravindran R (2017) Seroprevalence of Porcine Circovirus Type-2 (PCV2) and molecular diagnosis of PCV2 associated reproductive failure in pig population of Nagaland. Indian J Vet Pathol 41(2):79\u201383","journal-title":"Indian J Vet Pathol"},{"issue":"12","key":"7946_CR30","first-page":"194","volume":"8","author":"L Varte","year":"2018","unstructured":"Varte L, Ravindran R, Chhangte L, Tonsing L (2018) Seroprevalence of Porcine Circovirus-2 associated reproductive failure in pigs of Mizoram. India Int J Livest Res 8(12):194\u2013200","journal-title":"India Int J Livest Res"},{"key":"7946_CR31","doi-asserted-by":"crossref","first-page":"119","DOI":"10.56093\/ijans.v89i2.87321","volume":"89","author":"JB Rajesh","year":"2019","unstructured":"Rajesh JB, Rajkhowa S, Dimri U, Prasad H, Pegu SR, Saikiya P, Chetan GE, Zosangpuii Z, Ajith Y, Choudhury M (2019) Seroprevalence of PCV2 in north eastern hill states of India. Indian J Anim Sci 89:119\u2013122","journal-title":"Indian J Anim Sci"},{"issue":"1","key":"7946_CR32","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5455\/ijlr.20180508053437","volume":"9","author":"P Talukdar","year":"2019","unstructured":"Talukdar P, Talukdar D, Sarma K, Saikia K (2019) Prospects and potentiality of improving pig farming in north Eastern Hill Region of India: an overview. Int J Livest Res 9(1):1\u201314. https:\/\/doi.org\/10.5455\/ijlr.20180508053437","journal-title":"Int J Livest Res"},{"issue":"1","key":"7946_CR33","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1186\/s12917-020-02304-8","volume":"16","author":"N Lv","year":"2020","unstructured":"Lv N, Zhu L, Li W, Li Z, Qian Q, Zhang T, Liu L, Hong J, Zheng X, Wang Y, Zhang Y, Chai J (2020) Molecular epidemiology and genetic variation analyses of porcine circovirus type 2 isolated from Yunnan Province in China from 2016\u20132019. BMC Vet Res 16(1):96","journal-title":"BMC Vet Res"},{"issue":"6","key":"7946_CR34","doi-asserted-by":"publisher","first-page":"2521","DOI":"10.1111\/tbed.13596","volume":"67","author":"V Saporiti","year":"2020","unstructured":"Saporiti V, Huerta E, Correa-Fiz F, Grosse Liesner B, Duran O, Segal\u00e9s J, Sibila M (2020) Detection and genotyping of Porcine circovirus 2 (PCV-2) and detection of Porcine circovirus 3 (PCV-3) in sera from fattening pigs of different European countries. Transbound Emerg Dis 67(6):2521\u20132531. https:\/\/doi.org\/10.1111\/tbed.13596","journal-title":"Transbound Emerg Dis"},{"key":"7946_CR35","doi-asserted-by":"publisher","DOI":"10.1111\/tbed.14158","author":"S Parthiban","year":"2021","unstructured":"Parthiban S, Ramesh A, Karuppannan AK, Dhinakar Raj G, Johnson Rajeswar J, Hemalatha S, Jaisree S, Senthilkumar K, Bakasubramanyam D, Parthiban M, Sarathchandra G (2021) Emergence of novel Porcine circovirus 2 genotypes in Southern India. Transbound Emerg Dis. https:\/\/doi.org\/10.1111\/tbed.14158","journal-title":"Transbound Emerg Dis"},{"issue":"1","key":"7946_CR36","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1186\/s12985-019-1156-2","volume":"16","author":"Z Hou","year":"2019","unstructured":"Hou Z, Wang H, Feng Y, Li Q, Li J (2019) A candidate DNA vaccine encoding a fusion protein of porcine complement C3d-P28 and ORF2 of porcine circovirus type 2 induces cross-protective immunity against PCV2b and PCV2d in pigs. Virol J 16(1):57","journal-title":"Virol J"},{"issue":"1","key":"7946_CR37","doi-asserted-by":"publisher","first-page":"10782","DOI":"10.1038\/s41598-019-47209-1","volume":"9","author":"GT Tsai","year":"2019","unstructured":"Tsai GT, Lin YC, Lin WH, Lin JH, Chiou MT, Liu HF, Lin CN (2019) Phylogeographic and genetic characterization of porcine circovirus type 2 in Taiwan from 2001\u20132017. Sci Rep 9(1):10782","journal-title":"Sci Rep"},{"key":"7946_CR38","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.virusres.2016.11.015","volume":"228","author":"T Kwon","year":"2017","unstructured":"Kwon T, Lee DU, Yoo SJ, Je SH, Shin JY, Lyoo YS (2017) Genotypic diversity of porcine circovirus type 2 (PCV2) and genotype shift to PCV2d in Korean pig population. Virus Res 228:24\u201329","journal-title":"Virus Res"},{"issue":"3","key":"7946_CR39","doi-asserted-by":"publisher","first-page":"1284","DOI":"10.1111\/tbed.13467","volume":"67","author":"Y Wang","year":"2020","unstructured":"Wang Y, Noll L, Lu N, Porter E, Stoy C, Zheng W, Liu X, Peddireddi L, Niederwerder M, Bai J (2020) Genetic diversity and prevalence of porcine circovirus type 3 (PCV3) and type 2 (PCV2) in the Midwest of the USA during 2016\u20132018. Transbound Emerg Dis 67(3):1284\u20131294","journal-title":"Transbound Emerg Dis"},{"issue":"8","key":"7946_CR40","doi-asserted-by":"publisher","first-page":"1016","DOI":"10.3390\/pathogens10081016","volume":"10","author":"M Sibila","year":"2021","unstructured":"Sibila M, Rocco C, Franzo G, Huerta E, Domingo M, N\u00fa\u00f1ez JI, Segales J (2021) Genotyping of porcine circovirus 2 (PCV-2) in vaccinated pigs suffering from PCV-2-systemic disease between 2009 and 2020 in Spain. Pathogens 10(8):1016","journal-title":"Pathogens"},{"issue":"2","key":"7946_CR41","doi-asserted-by":"publisher","first-page":"vez026","DOI":"10.1093\/ve\/vez026","volume":"5","author":"R Wei","year":"2019","unstructured":"Wei R, Xie J, Theuns S, Nauwynck HJ (2019) Changes on the viral capsid surface during the evolution of porcine circovirus type 2 (PCV2) from 2009 till 2018 may lead to a better receptor binding. Virus Evol 5(2):vez026. https:\/\/doi.org\/10.1093\/ve\/vez026","journal-title":"Virus Evol"},{"issue":"1","key":"7946_CR42","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.virusres.2009.05.015","volume":"145","author":"F Wang","year":"2009","unstructured":"Wang F, Guo X, Ge X, Wang Z, Chen Y, Cha Z, Yang H (2009) Genetic variation analysis of Chinese strains of porcine circovirus type 2. Virus Res 145(1):151\u2013156","journal-title":"Virus Res"},{"issue":"7","key":"7946_CR43","doi-asserted-by":"publisher","first-page":"e41463","DOI":"10.1371\/journal.pone.0041463","volume":"7","author":"L Guo","year":"2012","unstructured":"Guo L, Fu Y, Wang Y, Lu Y, Wei Y, Tang Q (2012) A Porcine Circovirus type 2 (PCV2) mutant with 234 amino acids in capsid protein showed more virulence in vivo, compared with classical PCV2a\/b strain. PLoS ONE 7(7):e41463. https:\/\/doi.org\/10.1371\/journal.pone.0041463","journal-title":"PLoS ONE"},{"key":"7946_CR44","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1186\/1743-422X-8-437","volume":"8","author":"S Jaganathan","year":"2011","unstructured":"Jaganathan S, Toung OP, Yee PL, Yew TD, Yoon CP, Keong LB (2011) Genetic characterization of Porcine Circovirus 2 found in Malaysia. Virol J 8:437. https:\/\/doi.org\/10.1186\/1743-422X-8-437","journal-title":"Virol J"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-022-07946-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11033-022-07946-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-022-07946-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T23:05:31Z","timestamp":1677107131000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11033-022-07946-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,10]]},"references-count":44,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["7946"],"URL":"https:\/\/doi.org\/10.1007\/s11033-022-07946-5","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,10]]},"assertion":[{"value":"19 July 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 September 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 October 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All the authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence this research paper.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study involves only collection of samples from ailing or asymptomatic animals and doesn\u2019t involve any animal trail studies hence institutional animal ethics committee approval not required for this study. Farm authorities and owners declared their oral consent before the collection of the blood samples as well to the related survey questions. The pigs were sampled by a qualified veterinarian following all applicable guidelines for the care and use of animal. This research work was governed by the Institutional Biosafety Committee (IBSC) (Approval number Lr. No. 0023\/DFBS\/3\/IBSC\/2020) and followed all the biosafety measures. All the methods were performed in accordance with the relevant guidelines and regulations of Institutional Biosafety Committee for the waste disposal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"All the authors reviewed the paper and given their consent for publication.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}