{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T12:11:17Z","timestamp":1770466277102,"version":"3.49.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T00:00:00Z","timestamp":1720828800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T00:00:00Z","timestamp":1720828800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1007\/s11033-024-09719-8","type":"journal-article","created":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T06:02:21Z","timestamp":1720850541000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluating the expression pattern of ATXN1 and CDC42EP1 genes and related long noncoding RNAs in oral squamous cell carcinoma"],"prefix":"10.1007","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8612-1468","authenticated-orcid":false,"given":"Samira","family":"Hajisadeghi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6016-4240","authenticated-orcid":false,"given":"Mehrad","family":"Rafiei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0717-6044","authenticated-orcid":false,"given":"Elahe","family":"Tahmasebi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5661-4544","authenticated-orcid":false,"given":"Mostafa","family":"Khafaei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,7,13]]},"reference":[{"key":"9719_CR1","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1042\/EBC20200032","volume":"65","author":"H Yan","year":"2021","unstructured":"Yan H, Bu P (2021) Non-coding RNA in cancer. Essays Biochem 65:625\u2013639. https:\/\/doi.org\/10.1042\/EBC20200032","journal-title":"Essays Biochem"},{"key":"9719_CR2","doi-asserted-by":"publisher","first-page":"78111","DOI":"10.1093\/nar\/gkz646","volume":"4","author":"S Lu","year":"2019","unstructured":"Lu S, Zhang J, Lian X, Sun L et al (2019) A hidden human proteome encoded by \u2018non-coding\u2019 genes. Nucleic Acids Res 4:78111\u201378125. https:\/\/doi.org\/10.1093\/nar\/gkz646","journal-title":"Nucleic Acids Res"},{"key":"9719_CR3","doi-asserted-by":"publisher","unstructured":"Aliperti V, Skonieczna J, Cerase A (2021) Long non-coding RNA (lncRNA) roles in Cell Biology, Neurodevelopment and Neurological disorders. Non-coding RNA. 7:36. https:\/\/doi.org\/10.3390\/ncrna7020036","DOI":"10.3390\/ncrna7020036"},{"key":"9719_CR4","doi-asserted-by":"publisher","first-page":"585","DOI":"10.3892\/ijo.2019.4850","volume":"55","author":"L Jiang","year":"2019","unstructured":"Jiang L, Li Z, Wang R (2019) Long non coding RNAs in lung cancer: regulation patterns, biologic function and diagnosis implications (review). Int J Oncol 55:585\u2013596. https:\/\/doi.org\/10.3892\/ijo.2019.4850","journal-title":"Int J Oncol"},{"key":"9719_CR5","doi-asserted-by":"publisher","first-page":"101300","DOI":"10.21037\/tcr-21-1771","volume":"24","author":"S Atarbashi-Moghadam","year":"2021","unstructured":"Atarbashi-Moghadam S, Vafadar S, Shafagh S, Kholghi-Oskooei V, Ghafouri-Fard S, Taheri M (2021) Expression of lncRNAs in salivary gland malignancies. Gene Rep 24:101300. https:\/\/doi.org\/10.21037\/tcr-21-1771","journal-title":"Gene Rep"},{"key":"9719_CR6","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1038\/s41580-022-00566-8","volume":"24","author":"JS Mattick","year":"2023","unstructured":"Mattick JS, Amaral PP, Carninci P et al (2023) Long non-coding RNAs: definitions, functions, challenges and recommendations. Nat Rev Mol Cell Biol 24:430\u2013447","journal-title":"Nat Rev Mol Cell Biol"},{"key":"9719_CR7","doi-asserted-by":"publisher","first-page":"D1295","DOI":"10.1038\/s41580-022-00566-8","volume":"50","author":"M Yang","year":"2022","unstructured":"Yang M, Lu H, Liu J, Wu S, Kim P, Zhou X (2022) lncRNAfunc: a knowledgebase of lncRNA function in human cancer. Nucleic Acids Res 50:D1295\u2013D1306. https:\/\/doi.org\/10.1038\/s41580-022-00566-8","journal-title":"Nucleic Acids Res"},{"key":"9719_CR8","doi-asserted-by":"publisher","first-page":"632","DOI":"10.3390\/ijms22020632","volume":"22","author":"K Taniue","year":"2021","unstructured":"Taniue K, Akimitsu N (2021) The functions and unique features of LncRNAs in Cancer Development and Tumorigenesis. Int J Mol Sci 22:632. https:\/\/doi.org\/10.3390\/ijms22020632","journal-title":"Int J Mol Sci"},{"key":"9719_CR9","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.suronc.2019.09.001","volume":"31","author":"L Liu","year":"2019","unstructured":"Liu L, Chen J, Cai X, Yao Z, Huang J (2019) Progress in targeted therapeutic drugs for oral squamous cell carcinoma. Surg Oncol 31:90\u201397. https:\/\/doi.org\/10.1016\/j.suronc.2019.09.001","journal-title":"Surg Oncol"},{"issue":"5","key":"9719_CR10","doi-asserted-by":"publisher","first-page":"E359","DOI":"10.1002\/ijc.29210","volume":"136","author":"J Ferlay","year":"2015","unstructured":"Ferlay J, Soerjomataram I, Dikshit R et al (2015) Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 136(5):E359\u2013E386. https:\/\/doi.org\/10.1002\/ijc.29210","journal-title":"Int J Cancer"},{"key":"9719_CR11","first-page":"11884","volume":"8","author":"C Rivera","year":"2015","unstructured":"Rivera C (2015) Essentials of oral cancer. Int J Clin Exp Pathol 8:11884\u201311894","journal-title":"Int J Clin Exp Pathol"},{"key":"9719_CR12","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.tripleo.2005.07.038","volume":"102","author":"J Massano","year":"2006","unstructured":"Massano J, Regateiro FS, Janu\u00e1rio G, Ferreira A (2006) Oral squamous cell carcinoma: review of prognostic and predictive factors. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102:67\u201376. https:\/\/doi.org\/10.1016\/j.tripleo.2005.07.038","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"9719_CR13","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1002\/cncr.33309","volume":"127","author":"BR Campbell","year":"2021","unstructured":"Campbell BR, Chen Z, Faden DL et al (2021) The mutational landscape of early- and typical-onset oral tongue squamous cell carcinoma. Cancer 127:544\u2013553. https:\/\/doi.org\/10.1002\/cncr.33309","journal-title":"Cancer"},{"key":"9719_CR14","doi-asserted-by":"publisher","unstructured":"Du Y, Shuai Y, Liu Z, Li H, Yin Y (2024) Astaxanthin Synergizes with Ionizing Radiation (IR) in Oral Squamous Cell Carcinoma (OSCC). Molecular biotechnology. 66: 1220\u20131228. https:\/\/doi.org\/10.1007\/s12033-023-01024-2","DOI":"10.1007\/s12033-023-01024-2"},{"key":"9719_CR15","doi-asserted-by":"publisher","first-page":"e185","DOI":"10.1111\/ajco.13399","volume":"17","author":"T Salmani","year":"2021","unstructured":"Salmani T, Ghaderian SMH, Hajiesmaeili M et al (2021) Hsa-miR-27a-3p and epidermal growth factor receptor expression analysis in glioblastoma FFPE samples. Asia Pac J Clin Oncol 17:e185\u2013e90. https:\/\/doi.org\/10.1111\/ajco.13399","journal-title":"Asia Pac J Clin Oncol"},{"key":"9719_CR16","doi-asserted-by":"publisher","first-page":"e0291921","DOI":"10.1371\/journal.pone.0291921","volume":"18","author":"M Masrour","year":"2023","unstructured":"Masrour M, Khanmohammadi S, Fallahtafti P, Rezaei N (2023) Long non-coding RNA as a potential diagnostic biomarker in head and neck squamous cell carcinoma: a systematic review and meta-analysis. PLoS ONE 18:e0291921. https:\/\/doi.org\/10.1371\/journal.pone.0291921","journal-title":"PLoS ONE"},{"key":"9719_CR17","doi-asserted-by":"publisher","first-page":"5944","DOI":"10.3390\/cancers13235944","volume":"13","author":"J Tang","year":"2021","unstructured":"Tang J, Fang X, Chen J, Zhang H, Tang Z (2021) Long non-coding RNA (lncRNA) in oral squamous cell carcinoma: biological function and clinical application. Cancers 13:5944. https:\/\/doi.org\/10.3390\/cancers13235944","journal-title":"Cancers"},{"issue":"9","key":"9719_CR18","doi-asserted-by":"publisher","first-page":"e0291921","DOI":"10.1371\/journal.pone.0291921","volume":"18","author":"M Masrour","year":"2023","unstructured":"Masrour M, Khanmohammadi S, Fallahtafti P, Rezaei N (2023) Long non-coding RNA as a potential diagnostic biomarker in head and neck squamous cell carcinoma: a systematic review and meta-analysis. PLoS ONE 18(9):e0291921","journal-title":"PLoS ONE"},{"key":"9719_CR19","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1038\/embor.2011.49","volume":"12","author":"X Tong","year":"2011","unstructured":"Tong X, Gui H, Jin F et al (2011) Ataxin-1 and brother of ataxin-1 are components of the notch signaling pathway. EMBO Rep 12:428\u2013435. https:\/\/doi.org\/10.1038\/embor.2011.49","journal-title":"EMBO Rep"},{"key":"9719_CR20","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1007\/s12032-017-1039-6","volume":"34","author":"L Li","year":"2017","unstructured":"Li L, Tang P, Li S, Qin X, Yang H, Wu C, Liu Y (2017) Notch signaling pathway networks in cancer metastasis: a new target for cancer therapy. Med Oncol 34:180\u2013190. https:\/\/doi.org\/10.1007\/s12032-017-1039-6","journal-title":"Med Oncol"},{"key":"9719_CR21","doi-asserted-by":"publisher","first-page":"18248","DOI":"10.18632\/oncotarget.15319","volume":"8","author":"AR Kang","year":"2017","unstructured":"Kang AR, An HT, Ko J, Kang S (2017) Ataxin-1 regulates epithelial-mesenchymal transition of cervical cancer cells. Oncotarget 8:18248\u201318259. https:\/\/doi.org\/10.18632\/oncotarget.15319","journal-title":"Oncotarget"},{"key":"9719_CR22","doi-asserted-by":"publisher","first-page":"283ra254","DOI":"10.1126\/scitranslmed.aaa1408","volume":"7","author":"N McGranahan","year":"2015","unstructured":"McGranahan N, Favero F, de Bruin EC, Birkbak NJ, Szallasi Z, Swanton C (2015) Clonal status of actionable driver events and the timing of mutational processes in cancer evolution. Sci Transl Med 7:283ra254. https:\/\/doi.org\/10.1126\/scitranslmed.aaa1408","journal-title":"Sci Transl Med"},{"key":"9719_CR23","doi-asserted-by":"publisher","first-page":"94606","DOI":"10.18632\/oncotarget.21814","volume":"8","author":"AR Kang","year":"2017","unstructured":"Kang AR, An HT, Ko J, Choi EJ, Kang S (2017) Ataxin-1 is involved in tumorigenesis of cervical cancer cells via the EGFR-RAS-MAPK signaling pathway. Oncotarget 8:94606\u201394618. https:\/\/doi.org\/10.18632\/oncotarget.21814","journal-title":"Oncotarget"},{"key":"9719_CR24","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.3390\/pharmaceutics15041249","volume":"15","author":"T Jesenko","year":"2023","unstructured":"Jesenko T, Brezar SK, Cemazar M et al (2023) Targeting non-coding RNAs for the development of Novel Hepatocellular Carcinoma Therapeutic approaches. Pharmaceutics 15:1249. https:\/\/doi.org\/10.3390\/pharmaceutics15041249","journal-title":"Pharmaceutics"},{"key":"9719_CR25","doi-asserted-by":"publisher","first-page":"1709","DOI":"10.1042\/BST20160219","volume":"44","author":"AJ Farrugia","year":"2016","unstructured":"Farrugia AJ, Calvo F (2016) The Borg family of Cdc42 effector proteins Cdc42EP1-5. Biochem Soc Trans 44:1709\u20131716. https:\/\/doi.org\/10.1042\/BST20160219","journal-title":"Biochem Soc Trans"},{"key":"9719_CR26","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1093\/jmcb\/mjx044","volume":"10","author":"S Cohen","year":"2018","unstructured":"Cohen S, Kovari DT, Wei W, Keate R, Curtis JE, Nie S (2018) Cdc42 regulates the cellular localization of Cdc42ep1 in controlling neural crest cell migration. J Mol Cell Biol 10:376\u2013387. https:\/\/doi.org\/10.1093\/jmcb\/mjx044","journal-title":"J Mol Cell Biol"},{"key":"9719_CR27","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1091\/mbc.E13-09-0543","volume":"25","author":"Z Liu","year":"2014","unstructured":"Liu Z, Vong QP, Liu C, Zheng Y (2014) Borg5 is required for angiogenesis by regulating persistent directional migration of the cardiac microvascular endothelial cells. Mol Biol Cell 25:841\u2013851. https:\/\/doi.org\/10.1091\/mbc.E13-09-0543","journal-title":"Mol Biol Cell"},{"key":"9719_CR28","doi-asserted-by":"publisher","first-page":"110718","DOI":"10.1016\/j.ygeno.2023.110718","volume":"115","author":"X Liu","year":"2023","unstructured":"Liu X, Wu J, Yang B et al (2023) hsa_circ_0005991 promotes epithelial-mesenchymal transition by regulating miR-30b-3p\/Cdc42EP1 axis in ovary endometriosis. Genomics 115:110718. https:\/\/doi.org\/10.1016\/j.ygeno.2023.110718","journal-title":"Genomics"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-024-09719-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11033-024-09719-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-024-09719-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T03:40:03Z","timestamp":1738726803000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11033-024-09719-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,13]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["9719"],"URL":"https:\/\/doi.org\/10.1007\/s11033-024-09719-8","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,13]]},"assertion":[{"value":"10 May 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 June 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 July 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was performed in line with the principles of the Declaration of Helsinki. The code of ethics No IR.BMSU.BLC.1401.042 was obtained from the research ethics committee of Baqiatallah University of Medical Sciences.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"796"}}