{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:07:26Z","timestamp":1792678046282,"version":"4.5.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1007\/s11033-026-11556-w","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T06:41:14Z","timestamp":1772088074000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Paraprobiotic Lactiplantibacillus plantarum MYO ameliorates dexamethasone-induced muscle atrophy: implications for age-related sarcopenia"],"prefix":"10.1007","volume":"53","author":[{"given":"Meehee","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun-young","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyeon Jeong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duseong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Won","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seunghun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jisoo","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,26]]},"reference":[{"issue":"1","key":"11556_CR1","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1093\/ageing\/afy169","volume":"48","author":"AJ Cruz-Jentoft","year":"2019","unstructured":"Cruz-Jentoft AJ et al (2019) Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing 48(1):16\u201331","journal-title":"Age Ageing"},{"issue":"8","key":"11556_CR2","doi-asserted-by":"publisher","first-page":"e0289379","DOI":"10.1371\/journal.pone.0289379","volume":"18","author":"SN Wan","year":"2023","unstructured":"Wan SN et al (2023) Incident sarcopenia in hospitalized older people: A systematic review. PLoS ONE 18(8):e0289379","journal-title":"PLoS ONE"},{"issue":"5","key":"11556_CR3","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1002\/jcsm.12483","volume":"10","author":"J Bauer","year":"2019","unstructured":"Bauer J et al (2019) Sarcopenia: A time for Action. An SCWD position paper. J Cachexia Sarcopenia Muscle 10(5):956\u2013961","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"11556_CR4","doi-asserted-by":"publisher","first-page":"155533","DOI":"10.1016\/j.metabol.2023.155533","volume":"144","author":"S Yuan","year":"2023","unstructured":"Yuan S, Larsson SC (2023) Epidemiology of sarcopenia: Prevalence, risk factors, and consequences. Metabolism 144:155533","journal-title":"Metabolism"},{"issue":"5","key":"11556_CR5","doi-asserted-by":"publisher","first-page":"1533","DOI":"10.3390\/nu12051533","volume":"12","author":"RN Marshall","year":"2020","unstructured":"Marshall RN et al (2020) Nutritional strategies to offset Disuse-Induced skeletal muscle atrophy and anabolic resistance in older adults: from Whole-Foods to isolated ingredients. Nutrients 12(5):1533","journal-title":"Nutrients"},{"issue":"3","key":"11556_CR6","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1002\/jcsm.12709","volume":"12","author":"WQ Xie","year":"2021","unstructured":"Xie WQ et al (2021) Mouse models of sarcopenia: classification and evaluation. J Cachexia Sarcopenia Muscle 12(3):538\u2013554","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"10","key":"11556_CR7","doi-asserted-by":"publisher","first-page":"2163","DOI":"10.1016\/j.biocel.2013.05.036","volume":"45","author":"O Schakman","year":"2013","unstructured":"Schakman O et al (2013) Glucocorticoid-induced skeletal muscle atrophy. Int J Biochem Cell Biol 45(10):2163\u20132172","journal-title":"Int J Biochem Cell Biol"},{"issue":"9","key":"11556_CR8","doi-asserted-by":"publisher","first-page":"454","DOI":"10.3390\/fermentation8090454","volume":"8","author":"H Jeon","year":"2022","unstructured":"Jeon H et al (2022) Effects of Lactobacillus curvatus HY7602-Fermented antlers in Dexamethasone-Induced muscle atrophy. Fermentation 8(9):454","journal-title":"Fermentation"},{"key":"11556_CR9","doi-asserted-by":"crossref","unstructured":"Jang J et al (2022) Balanced free essential amino acids and resistance exercise training synergistically improve Dexamethasone-Induced impairments in muscle Strength, Endurance, and insulin sensitivity in mice. Int J Mol Sci 23(17):9735","DOI":"10.3390\/ijms23179735"},{"key":"11556_CR10","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.tma.2020.07.004","volume":"4","author":"M Kim","year":"2020","unstructured":"Kim M, Benayoun BA (2020) The microbiome: an emerging key player in aging and longevity. Transl Med Aging 4:103\u2013116","journal-title":"Transl Med Aging"},{"key":"11556_CR11","doi-asserted-by":"crossref","unstructured":"Lee K et al (2021) Lactobacillus plantarum HY7715 ameliorates sarcopenia by improving skeletal muscle mass and function in aged Balb\/c mice. Int J Mol Sci 22(18):10023","DOI":"10.3390\/ijms221810023"},{"key":"11556_CR12","doi-asserted-by":"publisher","first-page":"708096","DOI":"10.3389\/fnut.2021.708096","volume":"8","author":"CC Lee","year":"2021","unstructured":"Lee CC et al (2021) Lactobacillus plantarum TWK10 attenuates Aging-Associated muscle Weakness, bone Loss, and cognitive impairment by modulating the gut Microbiome in mice. Front Nutr 8:708096","journal-title":"Front Nutr"},{"key":"11556_CR13","doi-asserted-by":"crossref","unstructured":"Lee MC et al (2021) Lactobacillus plantarum TWK10 improves muscle mass and functional performance in frail older adults: A Randomized, Double-Blind clinical trial. Microorganisms 9(7):1466","DOI":"10.3390\/microorganisms9071466"},{"issue":"1","key":"11556_CR14","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1186\/s12934-020-01426-w","volume":"19","author":"BH Nataraj","year":"2020","unstructured":"Nataraj BH et al (2020) Postbiotics-parabiotics: the new horizons in microbial biotherapy and functional foods. Microb Cell Fact 19(1):168","journal-title":"Microb Cell Fact"},{"key":"11556_CR15","doi-asserted-by":"publisher","first-page":"105133","DOI":"10.1016\/j.rvsc.2023.105133","volume":"167","author":"SH Hosseini","year":"2024","unstructured":"Hosseini SH et al (2024) Beyond probiotics: exploring the potential of postbiotics and parabiotics in veterinary medicine. Res Vet Sci 167:105133","journal-title":"Res Vet Sci"},{"issue":"1","key":"11556_CR16","doi-asserted-by":"publisher","first-page":"2425838","DOI":"10.1080\/19476337.2024.2425838","volume":"22","author":"W Franco","year":"2024","unstructured":"Franco W (2024) Postbiotics and parabiotics derived from bacteria and yeast: current trends and future perspectives. CyTA - J Food 22(1):2425838","journal-title":"CyTA - J Food"},{"issue":"12","key":"11556_CR17","doi-asserted-by":"publisher","first-page":"3321","DOI":"10.1038\/s41418-020-0580-6","volume":"27","author":"H Lee","year":"2020","unstructured":"Lee H et al (2020) Yin Yang 1 is required for PHD finger protein 20-mediated myogenic differentiation in vitro and in vivo. Cell Death Differ 27(12):3321\u20133336","journal-title":"Cell Death Differ"},{"issue":"6","key":"11556_CR18","doi-asserted-by":"publisher","first-page":"E495","DOI":"10.1152\/ajpendo.00389.2016","volume":"312","author":"SH Kang","year":"2017","unstructured":"Kang SH et al (2017) Forkhead box O3 plays a role in skeletal muscle atrophy through expression of E3 ubiquitin ligases MuRF-1 and atrogin-1 in cushing\u2019s syndrome. Am J Physiol Endocrinol Metab 312(6):E495\u2013e507","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"1","key":"11556_CR19","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1038\/s41467-020-20123-1","volume":"12","author":"R Sartori","year":"2021","unstructured":"Sartori R, Romanello V, Sandri M (2021) Mechanisms of muscle atrophy and hypertrophy: implications in health and disease. Nat Commun 12(1):330","journal-title":"Nat Commun"},{"issue":"8","key":"11556_CR20","doi-asserted-by":"publisher","first-page":"3516","DOI":"10.3390\/ijms26083516","volume":"26","author":"ALGd Souza","year":"2025","unstructured":"Souza ALGd et al (2025) Biomarkers of skeletal muscle atrophy based on atrogenes evaluation: A systematic review and Meta-Analysis study. Int J Mol Sci 26(8):3516","journal-title":"Int J Mol Sci"},{"issue":"4","key":"11556_CR21","doi-asserted-by":"publisher","first-page":"E715","DOI":"10.1152\/ajpendo.2000.279.4.E715","volume":"279","author":"OJ Shah","year":"2000","unstructured":"Shah OJ et al (2000) 4E-BP1 and S6K1: translational integration sites for nutritional and hormonal information in muscle. Am J Physiol Endocrinol Metab 279(4):E715\u2013E729","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"5","key":"11556_CR22","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1097\/SHK.0000000000001498","volume":"53","author":"JE Rupert","year":"2020","unstructured":"Rupert JE, Jengelley DHA, Zimmers TA (2020) Vitro, in Vivo, and in Silico methods for assessment of muscle size and muscle growth regulation. Shock 53(5):605\u2013615","journal-title":"Shock"},{"issue":"1","key":"11556_CR23","doi-asserted-by":"publisher","first-page":"E120","DOI":"10.1152\/ajpendo.00363.2002","volume":"284","author":"ET Schroeder","year":"2003","unstructured":"Schroeder ET et al (2003) Effects of an oral androgen on muscle and metabolism in older, community-dwelling men. Am J Physiol Endocrinol Metab 284(1):E120\u2013E128","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"6","key":"11556_CR24","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1038\/s41419-024-06851-y","volume":"15","author":"FM Zhang","year":"2024","unstructured":"Zhang FM et al (2024) Transcriptome profiling of fast\/glycolytic and slow\/oxidative muscle fibers in aging and obesity. Cell Death Dis 15(6):459","journal-title":"Cell Death Dis"},{"key":"11556_CR25","doi-asserted-by":"crossref","unstructured":"Moustogiannis A et al (2021) The effects of muscle cell aging on myogenesis. Int J Mol Sci 22(7):3721","DOI":"10.3390\/ijms22073721"},{"issue":"2","key":"11556_CR26","doi-asserted-by":"publisher","first-page":"271","DOI":"10.2215\/CJN.00380112","volume":"8","author":"O Supasyndh","year":"2013","unstructured":"Supasyndh O et al (2013) Effect of oral anabolic steroid on muscle strength and muscle growth in Hemodialysis patients. Clin J Am Soc Nephrol 8(2):271\u2013279","journal-title":"Clin J Am Soc Nephrol"},{"issue":"3","key":"11556_CR27","doi-asserted-by":"publisher","first-page":"e0122357","DOI":"10.1371\/journal.pone.0122357","volume":"10","author":"F Mohamed","year":"2015","unstructured":"Mohamed F et al (2015) Mechanisms underlying early rapid increases in creatinine in Paraquat poisoning. PLoS ONE 10(3):e0122357","journal-title":"PLoS ONE"},{"issue":"4","key":"11556_CR28","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1016\/0002-9343(77)90406-5","volume":"62","author":"H Jick","year":"1977","unstructured":"Jick H (1977) Adverse drug effects in relation to renal function. Am J Med 62(4):514\u2013517","journal-title":"Am J Med"},{"issue":"10","key":"11556_CR29","doi-asserted-by":"publisher","first-page":"4533","DOI":"10.21873\/anticanres.16647","volume":"43","author":"K Hashimoto","year":"2023","unstructured":"Hashimoto K et al (2023) Serum creatinine elevation as a risk factor for Niraparib-induced hematologic toxicity. Anticancer Res 43(10):4533\u20134541","journal-title":"Anticancer Res"},{"key":"11556_CR30","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1515\/hukin-2017-0071","volume":"58","author":"GA Callegari","year":"2017","unstructured":"Callegari GA et al (2017) Creatine kinase and lactate dehydrogenase responses after different resistance and aerobic exercise protocols. J Hum Kinet 58:65\u201372","journal-title":"J Hum Kinet"},{"issue":"6","key":"11556_CR31","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1515\/CCLM.2010.179","volume":"48","author":"P Brancaccio","year":"2010","unstructured":"Brancaccio P, Lippi G, Maffulli N (2010) Biochemical markers of muscular damage. Clin Chem Lab Med 48(6):757\u2013767","journal-title":"Clin Chem Lab Med"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-026-11556-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11033-026-11556-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-026-11556-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T06:41:17Z","timestamp":1772088077000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11033-026-11556-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,26]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["11556"],"URL":"https:\/\/doi.org\/10.1007\/s11033-026-11556-w","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,26]]},"assertion":[{"value":"18 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"All animal procedures were approved by the Institutional Animal Care and Use Committee (IACUC) of Chungnam National University Hospital and performed in accordance with the guidelines and regulations (Approval number: CNUH-2024-IA0052).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}}],"article-number":"432"}}