{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T01:43:06Z","timestamp":1784166186228,"version":"3.55.0"},"reference-count":58,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1007\/s11033-026-11562-y","type":"journal-article","created":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T14:47:13Z","timestamp":1771426033000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Natural compounds: a promising therapeutic option for managing colistin-resistant bacteria and improving colistin activity"],"prefix":"10.1007","volume":"53","author":[{"given":"Milad","family":"Kashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Chegini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyede Vania","family":"Amiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammadreza","family":"Arabestani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aref","family":"Shariati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,18]]},"reference":[{"key":"11562_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2021.106103","volume":"170","author":"T Pulingam","year":"2022","unstructured":"Pulingam T, Parumasivam T, Gazzali AM, Sulaiman AM, Chee JY, Lakshmanan M, Chin CF, Sudesh K (2022) Antimicrobial resistance: prevalence, economic burden, mechanisms of resistance and strategies to overcome. Eur J Pharm Sci 170:106103","journal-title":"Eur J Pharm Sci"},{"key":"11562_CR2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics9040196","author":"S Morris","year":"2020","unstructured":"Morris S, Cerceo E (2020) Trends, epidemiology, and management of multi-drug resistant gram-negative bacterial infections in the hospitalized setting. Antibiotics (Basel, Switzerland). https:\/\/doi.org\/10.3390\/antibiotics9040196","journal-title":"Antibiotics (Basel, Switzerland)"},{"issue":"1","key":"11562_CR3","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1080\/22221751.2020.1754133","volume":"9","author":"MAE El-Sayed Ahmed","year":"2020","unstructured":"El-Sayed Ahmed MAE, Zhong LL, Shen C, Yang Y, Doi Y, Tian GB (2020) Colistin and its role in the era of antibiotic resistance: an extended review (2000\u20132019). Emerg Microbes Infect 9(1):868\u2013885","journal-title":"Emerg Microbes Infect"},{"issue":"6","key":"11562_CR4","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/j.ijantimicag.2016.06.023","volume":"48","author":"S Baron","year":"2016","unstructured":"Baron S, Hadjadj L, Rolain JM, Olaitan AO (2016) Molecular mechanisms of polymyxin resistance: knowns and unknowns. Int J Antimicrob Agents 48(6):583\u2013591","journal-title":"Int J Antimicrob Agents"},{"key":"11562_CR5","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2014.00643","volume":"5","author":"AO Olaitan","year":"2014","unstructured":"Olaitan AO, Morand S, Rolain JM (2014) Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria. Front Microbiol 5:643","journal-title":"Front Microbiol"},{"key":"11562_CR6","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/4315030","author":"J Sharma","year":"2022","unstructured":"Sharma J, Sharma D, Singh A, Sunita K (2022) Colistin resistance and management of drug resistant infections. Can J Infect Dis Med Microbiol. https:\/\/doi.org\/10.1155\/2022\/4315030","journal-title":"Can J Infect Dis Med Microbiol"},{"issue":"1","key":"11562_CR7","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1080\/14787210.2020.1705155","volume":"18","author":"ARM Coates","year":"2020","unstructured":"Coates ARM, Hu Y, Holt J, Yeh P (2020) Antibiotic combination therapy against resistant bacterial infections: synergy, rejuvenation and resistance reduction. Expert Rev Anti-Infect Ther 18(1):5\u201315","journal-title":"Expert Rev Anti-Infect Ther"},{"key":"11562_CR8","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25061340","author":"Z Breijyeh","year":"2020","unstructured":"Breijyeh Z, Jubeh B, Karaman R (2020) Resistance of gram-negative bacteria to current antibacterial agents and approaches to resolve it. Molecules. https:\/\/doi.org\/10.3390\/molecules25061340","journal-title":"Molecules"},{"key":"11562_CR9","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.723233","volume":"12","author":"D Stan","year":"2021","unstructured":"Stan D, Enciu AM, Mateescu AL, Ion AC, Brezeanu AC, Stan D, Tanase C (2021) Natural compounds with antimicrobial and antiviral effect and nanocarriers used for their transportation. Front Pharmacol 12:723233","journal-title":"Front Pharmacol"},{"issue":"2","key":"11562_CR10","first-page":"29","volume":"1","author":"SM Al-khazraji","year":"2022","unstructured":"Al-khazraji SM, Hossain M, Hassoon A (2022) Estimation of some bioactive substances and antibacterial activity of Zingiber officinale (ginger) extract. J Biomed Biochem 1(2):29\u201333","journal-title":"J Biomed Biochem"},{"issue":"1","key":"11562_CR11","first-page":"31","volume":"1","author":"R Alarkwazi","year":"2022","unstructured":"Alarkwazi R, Abdulreda G, Ali AS (2022) Secondary metabolism compounds study of essential oils for the Mentha spicata L. and Ocimum basilicum L. J Biomed Biochem 1(1):31\u201337","journal-title":"J Biomed Biochem"},{"issue":"3","key":"11562_CR12","first-page":"34","volume":"1","author":"M Hossain","year":"2022","unstructured":"Hossain M, Al-khazraji SM, Hassoon A (2022) Estimation of some essential oils and study antibacterial activity of Rosmarinus officinalis extract. J Biomed Biochem 1(3):34\u201338","journal-title":"J Biomed Biochem"},{"issue":"3","key":"11562_CR13","first-page":"15","volume":"1","author":"AS Salman","year":"2022","unstructured":"Salman AS (2022) Antibacterial effect of onion\u2018s infusion and garlic\u2018s infusion on Escherichia coli isolated from urine samples. J Biomed Biochem 1(3):15\u201320","journal-title":"J Biomed Biochem"},{"issue":"12","key":"11562_CR14","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0145053","volume":"10","author":"A Ahmad","year":"2015","unstructured":"Ahmad A, Wani MY, Khan A, Manzoor N, Molepo J (2015) Synergistic interactions of eugenol-tosylate and its congeners with Fluconazole against Candida albicans. PLoS One 10(12):e0145053","journal-title":"PLoS One"},{"key":"11562_CR15","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/4045013","volume":"2018","author":"ML Rangel","year":"2018","unstructured":"Rangel ML, de Aquino SG, de Lima JM, Castellano LR, de Castro RD (2018) In vitro effect of Cinnamomum zeylanicum Blume essential oil on Candida spp. involved in oral infections. Evid Based Complement Alternat Med 2018:4045013","journal-title":"Evid Based Complement Alternat Med"},{"issue":"1","key":"11562_CR16","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1080\/09603123.2024.2348094","volume":"35","author":"W Ben Selma","year":"2025","unstructured":"Ben Selma W, Ferjeni S, Farouk A, Marzouk M, Boukadida J (2025) Antimicrobial activity of cinnamomum zeylanicum essential oil against colistin-resistant gram-negative bacteria. Int J Environ Health Res 35(1):169\u2013181","journal-title":"Int J Environ Health Res"},{"issue":"1","key":"11562_CR17","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1007\/s00284-024-03981-6","volume":"82","author":"S Dhaouadi","year":"2024","unstructured":"Dhaouadi S, Ghorbel SKB, Bouglita W, Chaari S, Dhifi W, Khrouf R, Cherif A, Elandoulsi RB (2024) The potency of Cupressus sempervirens and Eucalyptus globulus essential oils against Antibiotic-Resistant Escherichia coli and mammaliicoccus Sciuri from diseased animals in Tunisia. Curr Microbiol 82(1):14","journal-title":"Curr Microbiol"},{"key":"11562_CR18","doi-asserted-by":"publisher","first-page":"1808","DOI":"10.3389\/fmicb.2018.01808","volume":"9","author":"A Cannatelli","year":"2018","unstructured":"Cannatelli A, Principato S, Colavecchio OL, Pallecchi L, Rossolini GM (2018) Synergistic activity of colistin in combination with resveratrol against colistin-resistant Gram-negative pathogens. Front Microbiol 9:1808","journal-title":"Front Microbiol"},{"issue":"12","key":"11562_CR19","doi-asserted-by":"publisher","first-page":"2983","DOI":"10.1093\/jac\/dkad342","volume":"78","author":"Q Sheng","year":"2023","unstructured":"Sheng Q, Wang N, Zhou Y, Deng X, Hou X, Wang J, Qiu J, Deng Y (2023) A new function of thymol nanoemulsion for reversing colistin resistance in Salmonella enterica serovar typhimurium infection. J Antimicrob Chemother 78(12):2983\u20132994","journal-title":"J Antimicrob Chemother"},{"key":"11562_CR20","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-018-0303-7","volume":"7","author":"YM Wang","year":"2018","unstructured":"Wang YM, Kong LC, Liu J, Ma HX (2018) Synergistic effect of eugenol with colistin against clinical isolated colistin-resistant Escherichia coli strains. Antimicrob Resist Infect Control 7:17","journal-title":"Antimicrob Resist Infect Control"},{"issue":"19","key":"11562_CR21","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e38281","volume":"10","author":"W Ben Selma","year":"2024","unstructured":"Ben Selma W, Farouk A, Ban Z, Ferjeni M, Alsulami T, Ali H, Boukadida J (2024) Thymus algeriensis essential oil: phytochemical investigation, bactericidal activity, synergistic effect with colistin, molecular docking, and dynamics analysis against Gram-negative bacteria resistant to colistin. Heliyon 10(19):e38281","journal-title":"Heliyon"},{"key":"11562_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2024.117487","volume":"180","author":"P Cheng","year":"2024","unstructured":"Cheng P, Sun Y, Wang B, Liang S, Yang Y, Gui S, Zhang K, Qu S, Li L (2024) Mechanism of synergistic action of colistin with resveratrol and baicalin against mcr-1-positive Escherichia coli. Biomed Pharmacother 180:117487","journal-title":"Biomed Pharmacother"},{"issue":"10","key":"11562_CR23","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.00341-24","volume":"12","author":"F Tang","year":"2024","unstructured":"Tang F, Peng W, Kou X, Chen Z, Zhang L (2024) High-throughput screening identification of apigenin that reverses the colistin resistance of mcr-1-positive pathogens. Microbiol Spectr 12(10):e0034124","journal-title":"Microbiol Spectr"},{"key":"11562_CR24","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2021.795150","volume":"9","author":"Y Lin","year":"2021","unstructured":"Lin Y, Zhang Y, Liu S, Ye D, Chen L, Huang N, Zeng W, Liao W, Zhan Y, Zhou T et al (2021) Quercetin rejuvenates sensitization of colistin-resistant Escherichia coli and Klebsiella pneumoniae clinical isolates to colistin. Front Chem 9:795150","journal-title":"Front Chem"},{"issue":"24","key":"11562_CR25","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202202903","volume":"12","author":"C Qin","year":"2023","unstructured":"Qin C, Tang N, Gan Y, Zhao H, Li Y, Tian GB, Yang YY, Yuan P, Ding X (2023) Liposomes co-delivering curcumin and colistin to overcome colistin resistance in bacterial infections. Adv Healthc Mater 12(24):e2202903","journal-title":"Adv Healthc Mater"},{"key":"11562_CR26","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics13060536","author":"P Anek","year":"2024","unstructured":"Anek P, Kumpangcum S, Roytrakul S, Khanongnuch C, Saenjum C, Phannachet K (2024) Antibacterial activities of phenolic compounds in miang extract: growth inhibition and change in protein expression of extensively drug-resistant Klebsiella pneumoniae. Antibiotics. https:\/\/doi.org\/10.3390\/antibiotics13060536","journal-title":"Antibiotics"},{"issue":"1","key":"11562_CR27","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-023-05302-2","volume":"6","author":"K Gadar","year":"2023","unstructured":"Gadar K, de Dios R, Kade\u0159\u00e1bkov\u00e1 N, Prescott TAK, Mavridou DAI, McCarthy RR (2023) Disrupting iron homeostasis can potentiate colistin activity and overcome colistin resistance mechanisms in Gram-Negative Bacteria. Commun Biol 6(1):937","journal-title":"Commun Biol"},{"issue":"10","key":"11562_CR28","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1038\/s41429-024-00753-z","volume":"77","author":"Z Fan","year":"2024","unstructured":"Fan Z, Li Z, Fu T, Feng Y, Chen Y, Liu H, Du B, Cui X, Zhao H, Xue G et al (2024) Inhibition of the ATP synthase increases sensitivity of Escherichia coli carrying mcr-1 to polymyxin B. J Antibiot 77(10):685\u2013696","journal-title":"J Antibiot"},{"key":"11562_CR29","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.jgar.2022.01.026","volume":"29","author":"M Vestergaard","year":"2022","unstructured":"Vestergaard M, Bald D, Ingmer H (2022) Targeting the ATP synthase in bacterial and fungal pathogens: beyond Mycobacterium tuberculosis. J Glob Antimicrob Resist 29:29\u201341","journal-title":"J Glob Antimicrob Resist"},{"key":"11562_CR30","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics11081073","author":"A Bonetti","year":"2022","unstructured":"Bonetti A, Tugnoli B, Piva A, Grilli E (2022) Thymol as an adjuvant to restore antibiotic efficacy and reduce antimicrobial resistance and virulence gene expression in enterotoxigenic Escherichia coli strains. Antibiotics. https:\/\/doi.org\/10.3390\/antibiotics11081073","journal-title":"Antibiotics"},{"key":"11562_CR31","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2021.120085","volume":"287","author":"R Du","year":"2021","unstructured":"Du R, Lv Q, Hu W, Hou X, Zhou Y, Deng X, Sun L, Li L, Deng Y, Wang J (2021) Phloretin potentiates polymyxin E activity against gram-negative bacteria. Life Sci 287:120085","journal-title":"Life Sci"},{"key":"11562_CR32","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2024.1491363","volume":"15","author":"M Kashi","year":"2024","unstructured":"Kashi M, Noei M, Chegini Z, Shariati A (2024) Natural compounds in the fight against Staphylococcus aureus biofilms: a review of antibiofilm strategies. Front Pharmacol 15:1491363","journal-title":"Front Pharmacol"},{"key":"11562_CR33","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics11060787","author":"N Hazime","year":"2022","unstructured":"Hazime N, Belguesmia Y, Barras A, Amiche M, Boukherroub R, Drider D (2022) Enhanced antibacterial activity of dermaseptin through its immobilization on alginate nanoparticles-effects of menthol and lactic acid on its potentialization. Antibiotics (Basel, Switzerland). https:\/\/doi.org\/10.3390\/antibiotics11060787","journal-title":"Antibiotics (Basel, Switzerland)"},{"key":"11562_CR34","doi-asserted-by":"publisher","DOI":"10.3390\/ph15060682","author":"N Hazime","year":"2022","unstructured":"Hazime N, Belguesmia Y, Kempf I, Barras A, Drider D, Boukherroub R (2022) Enhancing colistin activity against colistin-resistant Escherichia coli through combination with alginate nanoparticles and small molecules. Pharmaceuticals (Basel, Switzerland). https:\/\/doi.org\/10.3390\/ph15060682","journal-title":"Pharmaceuticals (Basel, Switzerland)"},{"issue":"2","key":"11562_CR35","doi-asserted-by":"publisher","first-page":"177","DOI":"10.3934\/microbiol.2023011","volume":"9","author":"R Abozahra","year":"2023","unstructured":"Abozahra R, Gaballah A, Abdelhamid SM (2023) Prevalence of the colistin resistance gene MCR-1 in colistin-resistant Klebsiella pneumoniae in Egypt. AIMS Microbiol 9(2):177\u2013194","journal-title":"AIMS Microbiol"},{"issue":"5","key":"11562_CR36","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.03666-22","volume":"11","author":"J Kong","year":"2023","unstructured":"Kong J, Wang Y, Yao Z, Lin Y, Zhang Y, Han Y, Zhou T, Ye J, Cao J (2023) Eugenol works synergistically with colistin against colistin-resistant Pseudomonas aeruginosa and Klebsiella pneumoniae isolates by enhancing membrane permeability. Microbiol Spectr 11(5):e0366622","journal-title":"Microbiol Spectr"},{"issue":"1","key":"11562_CR37","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1007\/s11033-025-10564-6","volume":"52","author":"M Kashi","year":"2025","unstructured":"Kashi M, Farahani A, Ahmadi A, Shariati A, Akbari M (2025) Antibacterial and antibiofilm efficacy of eugenol, carvacrol, and cinnamaldehyde against colistin-resistant Klebsiella pneumoniae. Mol Biol Rep 52(1):480","journal-title":"Mol Biol Rep"},{"key":"11562_CR38","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.01615","volume":"9","author":"Y Zhou","year":"2018","unstructured":"Zhou Y, Wang T, Guo Y, Liu S, Wang J, Shen Y, Tang S, Wang Y, Deng X (2018) In vitro\/vivo activity of potential MCR-1 inhibitor in combination with colistin againsts mcr-1-Positive Klebsiella pneumonia. Front Microbiol 9:1615","journal-title":"Front Microbiol"},{"issue":"11","key":"11562_CR39","doi-asserted-by":"publisher","first-page":"18640","DOI":"10.1002\/jcb.28908","volume":"120","author":"N Hassannejad","year":"2019","unstructured":"Hassannejad N, Bahador A, Rudbari NH, Modarressi MH, Parivar K (2019) In vivo antibacterial activity of Zataria multiflora Boiss extract and its components, carvacrol, and thymol, against colistin-resistant Acinetobacter baumannii in a Pneumonic BALB\/c mouse model. J Cell Biochem 120(11):18640\u201318649","journal-title":"J Cell Biochem"},{"issue":"4","key":"11562_CR40","doi-asserted-by":"publisher","first-page":"355","DOI":"10.29252\/beat-060414","volume":"6","author":"H Abdolrahimzadeh","year":"2018","unstructured":"Abdolrahimzadeh H, Bolandparvaz S, Abbasi HR, Dehghankhalili M, Paydar S, Dehghanian A, Hafez Ghoran S, Asadollahi M, Zare M (2018) Antimicrobial survey of local herbal drugs against Acinetobacter baumannii isolated from patients admitted to a Level-I trauma center. Bull Emerg Trauma 6(4):355\u2013362","journal-title":"Bull Emerg Trauma"},{"key":"11562_CR41","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.110606","volume":"130","author":"JC V\u00e1zquez-Ucha","year":"2020","unstructured":"V\u00e1zquez-Ucha JC, Mart\u00ednez-Guiti\u00e1n M, Lasarte-Monterrubio C, Conde-P\u00e9rez K, Arca-Su\u00e1rez J, \u00c1lvarez-Fraga L, P\u00e9rez A, Crecente-Campo J, Alonso MJ, Bou G et al (2020) Syzygium aromaticum (clove) and Thymus zygis (thyme) essential oils increase susceptibility to colistin in the nosocomial pathogens Acinetobacter baumannii and Klebsiella pneumoniae. Biomed Pharmacother 130:110606","journal-title":"Biomed Pharmacother"},{"issue":"10","key":"11562_CR42","doi-asserted-by":"publisher","first-page":"1899","DOI":"10.1007\/s10096-024-04884-x","volume":"43","author":"NA Mireles","year":"2024","unstructured":"Mireles NA, Malla CF, Tav\u00edo MM (2024) Cinnamaldehyde and baicalin reverse colistin resistance in enterobacterales and acinetobacter baumannii strains. Eur J Clin Microbiol Infect Dis 43(10):1899\u20131908","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"11562_CR43","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics12040739","author":"E Odaba\u015f K\u00f6se","year":"2023","unstructured":"Odaba\u015f K\u00f6se E, Koyuncu \u00d6zyurt \u00d6, Bilmen S, Er H, Kilit C, Aydemir E (2023) Quercetin: synergistic interaction with antibiotics against colistin-resistant Acinetobacter baumannii. Antibiotics. https:\/\/doi.org\/10.3390\/antibiotics12040739","journal-title":"Antibiotics"},{"issue":"3","key":"11562_CR44","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2023.106899","volume":"62","author":"Y Han","year":"2023","unstructured":"Han Y, Zhang Y, Zeng W, Huang Z, Cheng H, Kong J, Xu C, Xu M, Zhou T, Cao J (2023) Synergy with farnesol rejuvenates colistin activity against Colistin-resistant Gram-negative bacteria in vitro and in vivo. Int J Antimicrob Agents 62(3):106899","journal-title":"Int J Antimicrob Agents"},{"key":"11562_CR45","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics14010071","author":"A Korkut","year":"2025","unstructured":"Korkut A, \u00d6zkaya G\u00fcl S, Aydemir E, Er H, Odaba\u015f K\u00f6se E (2025) Cinnamic acid compounds (p-coumaric, ferulic, and p-methoxycinnamic acid) as effective antibacterial agents against colistin-resistant Acinetobacter baumannii. Antibiotics. https:\/\/doi.org\/10.3390\/antibiotics14010071","journal-title":"Antibiotics"},{"issue":"1","key":"11562_CR46","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1007\/s11033-025-10844-1","volume":"52","author":"M Kashi","year":"2025","unstructured":"Kashi M, Chegini Z, Khoshbayan A, Shariati A, Farahani A (2025) Natural compounds for colistin-resistant acinetobacter baumannii biofilm control: eugenol, cinnamaldehyde, and carvacrol. Mol Biol Rep 52(1):735","journal-title":"Mol Biol Rep"},{"issue":"Pt A","key":"11562_CR47","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2024.124907","volume":"667","author":"C Faivre","year":"2024","unstructured":"Faivre C, Imtiyaz FD, Buyck JM, Marchand S, Marcotte M, Henry T, Anton N, Collot M, Tewes F (2024) (E, E)-farnesol and myristic acid-loaded lipid nanoparticles overcome colistin resistance in Acinetobacter baumannii. Int J Pharm 667(Pt A):124907","journal-title":"Int J Pharm"},{"key":"11562_CR48","doi-asserted-by":"publisher","first-page":"2613","DOI":"10.2147\/IDR.S310081","volume":"14","author":"Z Li","year":"2021","unstructured":"Li Z, Ding Z, Liu Y, Jin X, Xie J, Li T, Zeng Z, Wang Z, Liu J (2021) Phenotypic and genotypic characteristics of biofilm formation in clinical isolates of acinetobacter baumannii. Infect Drug Resist 14:2613\u20132624","journal-title":"Infect Drug Resist"},{"issue":"8","key":"11562_CR49","doi-asserted-by":"publisher","DOI":"10.1007\/s00203-022-03135-x","volume":"204","author":"S Ozturk","year":"2022","unstructured":"Ozturk S (2022) Demonstration of the efficacy of curcumin on carbapenem-resistant Pseudomonas aeruginosa with Galleria mellonella larvae model. Arch Microbiol 204(8):524","journal-title":"Arch Microbiol"},{"issue":"1","key":"11562_CR50","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.01992-22","volume":"11","author":"L Wang","year":"2023","unstructured":"Wang L, Zhang Y, Lin Y, Cao J, Xu C, Chen L, Wang Y, Sun Y, Zheng X, Liu Y et al (2023) Resveratrol increases sensitivity of clinical colistin-Resistant Pseudomonas aeruginosa to colistin in vitro and in vivo. Microbiol Spectr 11(1):e0199222","journal-title":"Microbiol Spectr"},{"issue":"9","key":"11562_CR51","doi-asserted-by":"publisher","first-page":"2564","DOI":"10.1093\/jac\/dkaa200","volume":"75","author":"F Ghirga","year":"2020","unstructured":"Ghirga F, Stefanelli R, Cavinato L, Lo Sciuto A, Corradi S, Quaglio D, Calcaterra A, Casciaro B, Loffredo MR, Cappiello F et al (2020) A novel colistin adjuvant identified by virtual screening for ArnT inhibitors. J Antimicrob Chemother 75(9):2564\u20132572","journal-title":"J Antimicrob Chemother"},{"issue":"6273","key":"11562_CR52","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1126\/science.aad1172","volume":"351","author":"VI Petrou","year":"2016","unstructured":"Petrou VI, Herrera CM, Schultz KM, Clarke OB, Vendome J, Tomasek D, Banerjee S, Rajashankar KR, Belcher Dufrisne M, Kloss B et al (2016) Structures of aminoarabinose transferase ArnT suggest a molecular basis for lipid A glycosylation. Science 351(6273):608\u2013612","journal-title":"Science"},{"issue":"16","key":"11562_CR53","doi-asserted-by":"publisher","first-page":"10891","DOI":"10.1021\/acs.joc.0c01459","volume":"85","author":"D Quaglio","year":"2020","unstructured":"Quaglio D, Mangoni ML, Stefanelli R, Corradi S, Casciaro B, Vergine V, Lucantoni F, Cavinato L, Cammarone S, Loffredo MR et al (2020) ent-Beyerane diterpenes as a key platform for the development of ArnT-mediated colistin resistance inhibitors. J Org Chem 85(16):10891\u201310901","journal-title":"J Org Chem"},{"key":"11562_CR54","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2025.1548117","volume":"16","author":"M Kashi","year":"2025","unstructured":"Kashi M, Varseh M, Hariri Y, Chegini Z, Shariati A (2025) Natural compounds: new therapeutic approach for inhibition of Streptococcus mutans and dental caries. Front Pharmacol 16:1548117","journal-title":"Front Pharmacol"},{"key":"11562_CR55","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2024.103971","volume":"45","author":"M Azimzadeh","year":"2024","unstructured":"Azimzadeh M, Greco G, Farmani A, Pourhajibagher M, Taherkhani A, Alikhani MY, Bahador A (2024) Synergistic effects of nano curcumin mediated photodynamic inactivation and nano-silver@colistin against Pseudomonas aeruginosa biofilms. Photodiagnosis Photodyn Ther 45:103971","journal-title":"Photodiagnosis Photodyn Ther"},{"key":"11562_CR56","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2024.155768","volume":"130","author":"N Wang","year":"2024","unstructured":"Wang N, Sheng Q, Zhu H, Wang J, Qiu J, Cui M, Zhou Y, Deng X, Deng Y, Wang L (2024) Enhancing the effectiveness of Polymyxin E with a Fisetin Nanoemulsion against a Colistin-resistant Salmonella typhimurium infection. Phytomedicine 130:155768","journal-title":"Phytomedicine"},{"issue":"2","key":"11562_CR57","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.mimet.2009.01.020","volume":"77","author":"M Arabski","year":"2009","unstructured":"Arabski M, Wasik S, Dworecki K, Kaca W (2009) Laser interferometric and cultivation methods for measurement of colistin\/ampicilin and saponin interactions with smooth and rough of proteus mirabilis lipopolysaccharides and cells. J Microbiol Methods 77(2):178\u2013183","journal-title":"J Microbiol Methods"},{"issue":"4","key":"11562_CR58","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0092876","volume":"9","author":"PG Vidigal","year":"2014","unstructured":"Vidigal PG, M\u00fcsken M, Becker KA, H\u00e4ussler S, Wingender J, Steinmann E, Kehrmann J, Gulbins E, Buer J, Rath PM et al (2014) Effects of green tea compound epigallocatechin-3-gallate against Stenotrophomonas maltophilia infection and biofilm. PLoS One 9(4):e92876","journal-title":"PLoS One"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-026-11562-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11033-026-11562-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-026-11562-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T15:04:41Z","timestamp":1771427081000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11033-026-11562-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,18]]},"references-count":58,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["11562"],"URL":"https:\/\/doi.org\/10.1007\/s11033-026-11562-y","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,18]]},"assertion":[{"value":"17 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"During the preparation of this work, the authors utilized Google Gemini strictly to improve the readability, grammar, and linguistic quality of the manuscript. The authors reviewed and edited the output as needed and take full responsibility for the content of the publication. It is declared that no part of the scientific content or the original text was generated by the AI tool; it was used solely to refine the authors\u2019 original writing.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Generative AI and AI-assisted technologies in the writing process"}}],"article-number":"398"}}