{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T15:52:48Z","timestamp":1781884368033,"version":"3.54.5"},"reference-count":99,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T00:00:00Z","timestamp":1781827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T00:00:00Z","timestamp":1781827200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1007\/s11033-026-12148-4","type":"journal-article","created":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T13:50:20Z","timestamp":1781877020000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["RNA acetylation modification ac4C: An emerging regulatory hub of RNA metabolism disruption in Alzheimer\u2019s disease"],"prefix":"10.1007","volume":"53","author":[{"given":"Liping","family":"Xing","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhui","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kexin","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Honglin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,19]]},"reference":[{"issue":"3","key":"12148_CR1","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1016\/S1474-4422(25)00425-9","volume":"25","author":"K Vossel","year":"2026","unstructured":"Vossel K, Johnson EL, Cretin B, Matsumoto R (2026) Epileptic activity in Alzheimer\u2019s disease: emerging insights and therapeutic implications. Lancet Neurol 25(3):294\u2013307","journal-title":"Lancet Neurol"},{"issue":"2","key":"12148_CR2","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1093\/procel\/pwae026","volume":"16","author":"Q Zheng","year":"2025","unstructured":"Zheng Q, Wang X (2025) Alzheimer\u2019s disease: insights into pathology, molecular mechanisms, and therapy. Protein Cell 16(2):83\u2013120","journal-title":"Protein Cell"},{"issue":"1","key":"12148_CR3","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/s13073-023-01155-w","volume":"15","author":"M Jorfi","year":"2023","unstructured":"Jorfi M, Maaser-Hecker A, Tanzi RE (2023) The neuroimmune axis of Alzheimer\u2019s disease. Genome Med 15(1):6","journal-title":"Genome Med"},{"key":"12148_CR4","doi-asserted-by":"publisher","first-page":"102775","DOI":"10.1016\/j.arr.2025.102775","volume":"109","author":"VV Sugandhi","year":"2025","unstructured":"Sugandhi VV, Gadhave DG, Ugale AR, Kulkarni N, Nangare SN, Patil HP, Rath S, Saxena R, Lavate A, Patel AT, Jadhav A (2025) Paudel K. R. Advances in Alzheimer\u2019s therapy: Exploring neuropathological mechanisms to revolutionize the future therapeutic landscape. Ageing Res Rev 109:102775","journal-title":"Ageing Res Rev"},{"issue":"3","key":"12148_CR5","doi-asserted-by":"publisher","first-page":"543","DOI":"10.4103\/1673-5374.320970","volume":"17","author":"Y Ju","year":"2022","unstructured":"Ju Y, Tam KY (2022) Pathological mechanisms and therapeutic strategies for Alzheimer\u2019s disease. Neural Regen Res 17(3):543\u2013549","journal-title":"Neural Regen Res"},{"issue":"6","key":"12148_CR6","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1007\/s11596-020-2281-2","volume":"40","author":"CC Zhu","year":"2020","unstructured":"Zhu CC, Fu SY, Chen YX, Li L, Mao RL, Wang JZ, Liu R, Liu Y, Wang XC (2020) Advances in drug therapy for alzheimer\u2019s disease. Curr Med Sci 40(6):999\u20131008","journal-title":"Curr Med Sci"},{"issue":"3","key":"12148_CR7","doi-asserted-by":"publisher","first-page":"837","DOI":"10.14336\/AD.2021.1119","volume":"13","author":"Y Liu","year":"2022","unstructured":"Liu Y, Chen X, Che Y, Li H, Zhang Z, Peng W, Yang J (2022) LncRNAs as the regulators of brain function and therapeutic targets for alzheimer\u2019s disease. Aging Dis 13(3):837\u2013851","journal-title":"Aging Dis"},{"key":"12148_CR8","doi-asserted-by":"crossref","unstructured":"Rybak-Wolf A, Plass M (2021) RNA dynamics in alzheimer\u2019s disease. Molecules, 26(17):5113","DOI":"10.3390\/molecules26175113"},{"issue":"2","key":"12148_CR9","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1038\/s41593-021-00999-y","volume":"25","author":"ECB Johnson","year":"2022","unstructured":"Johnson ECB, Carter EK, Dammer EB, Duong DM, Gerasimov ES, Liu Y, Liu J, Betarbet R, Ping L, Yin L, Serrano GE, Beach TG, Peng J, De Jager PL, Haroutunian V, Zhang B, Gaiteri C, Bennett DA, Gearing M, Wingo TS, Wingo AP, Lah JJ, Levey AI, Seyfried NT (2022) Large-scale deep multi-layer analysis of Alzheimer\u2019s disease brain reveals strong proteomic disease-related changes not observed at the RNA level. Nat Neurosci 25(2):213\u2013225","journal-title":"Nat Neurosci"},{"key":"12148_CR10","doi-asserted-by":"publisher","first-page":"149852","DOI":"10.1016\/j.brainres.2025.149852","volume":"1865","author":"M Yao","year":"2025","unstructured":"Yao M, Liu A, Song J, Xing L, Huang Y, Li H (2025) The impact of epigenetic and epitranscriptomic modifications on Alzheimer\u2019s disease: the mysteries of DNA, RNA, and histone methylation. Brain Res 1865:149852","journal-title":"Brain Res"},{"key":"12148_CR11","doi-asserted-by":"crossref","unstructured":"Chatterjee B, Shen CJ, Majumder PRNA (2021) Modifications and RNA metabolism in neurological disease pathogenesis. Int J Mol Sci, 22(21):11870","DOI":"10.3390\/ijms222111870"},{"key":"12148_CR12","doi-asserted-by":"crossref","unstructured":"Yang H, Li Y, Huang L, Fang M, Xu S (2023) The epigenetic regulation of RNA N6-methyladenosine methylation in glycolipid metabolism. Biomolecules, 13(2):273","DOI":"10.3390\/biom13020273"},{"issue":"5","key":"12148_CR13","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1261\/rna.079948.124","volume":"30","author":"S Schiffers","year":"2024","unstructured":"Schiffers S, Oberdoerffer S (2024) ac4C: a fragile modification with stabilizing functions in RNA metabolism. RNA 30(5):583\u2013594","journal-title":"RNA"},{"key":"12148_CR14","doi-asserted-by":"crossref","unstructured":"Gu Z, Zou L, Pan X, Yu Y, Liu Y, Zhang Z, Liu J, Mao S, Zhang J, Guo C, Li W, Geng J, Zhang W, Yao X, Shen B (2020) The role and mechanism of NAT10-mediated ac4C modification in tumor development and progression. MedComm 2024, 5(12): e70026","DOI":"10.1002\/mco2.70026"},{"issue":"12","key":"12148_CR15","doi-asserted-by":"publisher","first-page":"2168","DOI":"10.1038\/s41556-024-01548-y","volume":"26","author":"S Zhang","year":"2024","unstructured":"Zhang S, Huang F, Wang Y, Long Y, Li Y, Kang Y, Gao W, Zhang X, Wen Y, Wang Y, Pan L, Xia Y, Yang Z, Yang Y, Mo H, Li B, Hu J, Song Y, Zhang S, Dong S, Du X, Li Y, Liu Y, Liao W, Gao Y, Zhang Y, Chen H, Liang Y, Chen J, Weng H, Huang H (2024) NAT10-mediated mRNA N(4)-acetylcytidine reprograms serine metabolism to drive leukaemogenesis and stemness in acute myeloid leukaemia. Nat Cell Biol 26(12):2168\u20132182","journal-title":"Nat Cell Biol"},{"issue":"1","key":"12148_CR16","doi-asserted-by":"publisher","first-page":"e2944","DOI":"10.1002\/iub.2944","volume":"77","author":"W Zhang","year":"2025","unstructured":"Zhang W, Zhang J, Zhang Y, Zhai J, Sun B, Guo Y, Wang F (2025) The up-regulation of RIPK3 mediated by ac4C modification promotes oxidative stress-induced granulosa cell senescence by inhibiting the Nrf2\/HO-1 pathway. IUBMB Life 77(1):e2944","journal-title":"IUBMB Life"},{"issue":"4","key":"12148_CR17","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1515\/bchm2.1966.347.1.212","volume":"347","author":"HG Zachau","year":"1966","unstructured":"Zachau HG, D\u00fctting D, Feldmann H (1966) The structures of two serine transfer ribonucleic acids. Hoppe Seylers Z Physiol Chem 347(4):212\u2013235","journal-title":"Hoppe Seylers Z Physiol Chem"},{"issue":"2","key":"12148_CR18","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/0005-2787(72)90234-1","volume":"262","author":"Z Oashi","year":"1972","unstructured":"Oashi Z, Murao K, Yahagi T, Von Minden DL, Mccloskey JA, Nishimura S (1972) Characterization of C\u2009+\u2009located in the first position of the anticodon of Escherichia coli tRNA Met as N 4 -acetylcytidine [J]. Biochim Biophys Acta 262(2):209\u2013213","journal-title":"Biochim Biophys Acta"},{"issue":"4","key":"12148_CR19","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1016\/S0021-9258(17)38117-6","volume":"253","author":"G Thomas","year":"1978","unstructured":"Thomas G, Gordon J, Rogg H (1978) N4-Acetylcytidine. A previously unidentified labile component of the small subunit of eukaryotic ribosomes. J Biol Chem 253(4):1101\u20131105","journal-title":"J Biol Chem"},{"issue":"1","key":"12148_CR20","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1096\/fasebj.7.1.8422966","volume":"7","author":"E Bruenger","year":"1993","unstructured":"Bruenger E, Kowalak JA, Kuchino Y, Mccloskey JA, Mizushima H, Stetter KO (1993) Crain P. F. 5S rRNA modification in the hyperthermophilic archaea Sulfolobus solfataricus and Pyrodictium occultum. Faseb j 7(1):196\u2013200","journal-title":"Faseb j"},{"issue":"7","key":"12148_CR21","doi-asserted-by":"publisher","first-page":"1872","DOI":"10.1016\/j.cell.2018.10.030","volume":"175","author":"D Arango","year":"2018","unstructured":"Arango D, Sturgill D, Alhusaini N, Dillman AA, Sweet TJ, Hanson G, Hosogane M, Sinclair WR, Nanan KK, Mandler MD, Fox SD, Zengeya TT, Andresson T, Meier JL, Coller J, Oberdoerffer S (2018) Acetylation of Cytidine in mRNA Promotes Translation Efficiency. Cell 175(7):1872\u20131886e1824","journal-title":"Cell"},{"issue":"8","key":"12148_CR22","doi-asserted-by":"publisher","first-page":"3487","DOI":"10.1021\/jacs.1c11985","volume":"144","author":"D Bartee","year":"2022","unstructured":"Bartee D, Nance KD, Meier JL (2022) Site-Specific Synthesis of N(4)-Acetylcytidine in RNA Reveals Physiological Duplex Stabilization. J Am Chem Soc 144(8):3487\u20133496","journal-title":"J Am Chem Soc"},{"issue":"4","key":"12148_CR23","doi-asserted-by":"publisher","first-page":"2242","DOI":"10.1093\/nar\/gkv075","volume":"43","author":"S Sharma","year":"2015","unstructured":"Sharma S, Langhendries JL, Watzinger P, K\u00f6tter P, Entian KD, Lafontaine DL (2015) Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1\/THUMPD1 [J]. Nucleic Acids Res 43(4):2242\u20132258","journal-title":"Nucleic Acids Res"},{"issue":"9","key":"12148_CR24","doi-asserted-by":"publisher","first-page":"5226","DOI":"10.1093\/nar\/gkae262","volume":"52","author":"CR Ma","year":"2024","unstructured":"Ma CR, Liu N, Li H, Xu H, Zhou XL (2024) Activity reconstitution of Kre33 and Tan1 reveals a molecular ruler mechanism in eukaryotic tRNA acetylation. Nucleic Acids Res 52(9):5226\u20135240","journal-title":"Nucleic Acids Res"},{"issue":"4","key":"12148_CR25","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/j.ajhg.2022.02.001","volume":"109","author":"M Broly","year":"2022","unstructured":"Broly M, Polevoda BV, Awayda KM, Tong N, Lentini J, Besnard T, Deb W, O\u2019rourke D, Baptista J, Ellard S, Almannai M, Hashem M, Abdulwahab F, Shamseldin H, Al-Tala S, Alkuraya FS, Leon A, Van Loon RLE, Ferlini A, Sanchini M, Bigoni S, Ciorba A, Van Bokhoven H, Iqbal Z, Al-Maawali A, Al-Murshedi F, Ganesh A, Al-Mamari W, Lim SC, Pais LS, Brown N, Riazuddin S, B\u00e9zieau S, Fu D, Isidor B (2022) Cogn\u00e9 B., O\u2019connell M. R. THUMPD1 bi-allelic variants cause loss of tRNA acetylation and a syndromic neurodevelopmental disorder. Am J Hum Genet 109(4):587\u2013600","journal-title":"Am J Hum Genet"},{"issue":"3","key":"12148_CR26","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1093\/eurheartj\/ehae707","volume":"46","author":"C Yu","year":"2025","unstructured":"Yu C, Chen Y, Luo H, Lin W, Lin X, Jiang Q, Liu H, Liu W, Yang J, Huang Y, Fang J, He D, Han Y, Zheng S, Ren H, Xia X, Yu J, Chen L (2025) Zeng C. NAT10 promotes vascular remodelling via mRNA ac4C acetylation. Eur Heart J 46(3):288\u2013304","journal-title":"Eur Heart J"},{"issue":"15","key":"12148_CR27","doi-asserted-by":"publisher","first-page":"2797","DOI":"10.1016\/j.molcel.2022.05.016","volume":"82","author":"D Arango","year":"2022","unstructured":"Arango D, Sturgill D, Yang R, Kanai T, Bauer P, Roy J, Wang Z, Hosogane M, Schiffers S, Oberdoerffer S (2022) Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine. Mol Cell 82(15):2797\u20132814e2711","journal-title":"Mol Cell"},{"issue":"9","key":"12148_CR28","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1261\/rna.075747.120","volume":"26","author":"W Swinehart","year":"2020","unstructured":"Swinehart W, Deutsch C, Sarachan KL, Luthra A, Bacusmo JM, De Cr\u00e9cy-Lagard V, Swairjo MA, Agris PF, Iwata-Reuyl D (2020) Specificity in the biosynthesis of the universal tRNA nucleoside N(6)-threonylcarbamoyl adenosine (t(6)A)-TsaD is the gatekeeper. RNA 26(9):1094\u20131103","journal-title":"RNA"},{"key":"12148_CR29","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/j.omtn.2023.03.023","volume":"32","author":"L Xie","year":"2023","unstructured":"Xie L, Zhong X, Cao W, Liu J, Zu X, Chen L (2023) Mechanisms of NAT10 as ac4C writer in diseases. Mol Ther Nucleic Acids 32:359\u2013368","journal-title":"Mol Ther Nucleic Acids"},{"issue":"9","key":"12148_CR30","doi-asserted-by":"publisher","first-page":"e1045","DOI":"10.1002\/ctm2.1045","volume":"12","author":"MH Dalhat","year":"2022","unstructured":"Dalhat MH, Mohammed MRS, Alkhatabi HA, Rehan M, Ahmad A, Choudhry H (2022) Khan M. I. NAT10: An RNA cytidine transferase regulates fatty acid metabolism in cancer cells. Clin Transl Med 12(9):e1045","journal-title":"Clin Transl Med"},{"key":"12148_CR31","doi-asserted-by":"publisher","first-page":"1623276","DOI":"10.3389\/fcell.2025.1623276","volume":"13","author":"D Qin","year":"2025","unstructured":"Qin D, Liu Q, Ma X, Wang R, Lu T, Yang Y, Tang Z, Zhu Y (2025) Research progress on NAT10-mediated acetylation in normal development and disease. Front Cell Dev Biol 13:1623276","journal-title":"Front Cell Dev Biol"},{"issue":"5","key":"12148_CR32","doi-asserted-by":"publisher","first-page":"e738","DOI":"10.1002\/ctm2.738","volume":"12","author":"G Wang","year":"2022","unstructured":"Wang G, Zhang M, Zhang Y, Xie Y, Zou J, Zhong J, Zheng Z, Zhou X, Zheng Y, Chen B, Liu C (2022) NAT10-mediated mRNA N4-acetylcytidine modification promotes bladder cancer progression. Clin Transl Med 12(5):e738","journal-title":"Clin Transl Med"},{"issue":"16","key":"12148_CR33","doi-asserted-by":"publisher","first-page":"8514","DOI":"10.1093\/nar\/gkad628","volume":"51","author":"R Liu","year":"2023","unstructured":"Liu R, Wubulikasimu Z, Cai R, Meng F, Cui Q, Zhou Y, Li Y (2023) NAT10-mediated N4-acetylcytidine mRNA modification regulates self-renewal in human embryonic stem cells. Nucleic Acids Res 51(16):8514\u20138531","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"12148_CR34","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1186\/s13046-022-02551-7","volume":"41","author":"C Jin","year":"2022","unstructured":"Jin C, Wang T, Zhang D, Yang P, Zhang C, Peng W, Jin K, Wang L, Zhou J, Peng C, Tan Y, Ji J, Chen Z, Sun Q, Yang S, Tang J, Feng Y, Sun Y (2022) Acetyltransferase NAT10 regulates the Wnt\/\u03b2-catenin signaling pathway to promote colorectal cancer progression via ac(4)C acetylation of KIF23 mRNA. J Exp Clin Cancer Res 41(1):345","journal-title":"J Exp Clin Cancer Res"},{"issue":"1","key":"12148_CR35","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1038\/s41419-025-07528-w","volume":"16","author":"Z Sun","year":"2025","unstructured":"Sun Z, Wang Y, Zheng C, Xiao L, Zang Y, Fang L, Cui X, Chang M, Sun Q, Li W, Ren J (2025) NAT10 promotes the progression of clear cell renal cell carcinoma by regulating ac4C acetylation of NFE2L3 and activating AKT\/GSK3\u03b2 signaling pathway. Cell Death Dis 16(1):235","journal-title":"Cell Death Dis"},{"issue":"2","key":"12148_CR36","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1093\/hmg\/ddab244","volume":"31","author":"JA Pradeepkiran","year":"2021","unstructured":"Pradeepkiran JA, Munikumar M, Reddy AP, Reddy PH (2021) Protective effects of a small molecule inhibitor ligand against hyperphosphorylated tau-induced mitochondrial and synaptic toxicities in Alzheimer disease. Hum Mol Genet 31(2):244\u2013261","journal-title":"Hum Mol Genet"},{"issue":"23","key":"12148_CR37","doi-asserted-by":"publisher","first-page":"e2300898","DOI":"10.1002\/advs.202300898","volume":"10","author":"Q Yang","year":"2023","unstructured":"Yang Q, Lei X, He J, Peng Y, Zhang Y, Ling R, Wu C, Zhang G, Zheng B, Chen X, Zou B, Fu Z, Zhao L, Liu H, Hu Y, Yu J, Li F, Ye G, Li G (2023) N4-Acetylcytidine Drives Glycolysis Addiction in Gastric Cancer via NAT10\/SEPT9\/HIF-1\u03b1 Positive Feedback Loop. Adv Sci (Weinh) 10(23):e2300898","journal-title":"Adv Sci (Weinh)"},{"issue":"1\u20132","key":"12148_CR38","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1007\/s11010-020-03776-w","volume":"472","author":"Y Wu","year":"2020","unstructured":"Wu Y, Cao Y, Liu H, Yao M, Ma N, Zhang B (2020) Remodelin, an inhibitor of NAT10, could suppress hypoxia-induced or constitutional expression of HIFs in cells. Mol Cell Biochem 472(1\u20132):19\u201331","journal-title":"Mol Cell Biochem"},{"issue":"17","key":"12148_CR39","doi-asserted-by":"publisher","first-page":"3009","DOI":"10.1523\/JNEUROSCI.2321-22.2023","volume":"43","author":"M Zhang","year":"2023","unstructured":"Zhang M, Yang K, Wang QH, Xie L, Liu Q, Wei R, Tao Y, Zheng HL, Lin N, Xu H, Yang L, Wang H, Zhang T, Xue Z, Cao JL, Pan Z (2023) The Cytidine N-Acetyltransferase NAT10 Participates in Peripheral Nerve Injury-Induced Neuropathic Pain by Stabilizing SYT9 Expression in Primary Sensory Neurons. J Neurosci 43(17):3009\u20133027","journal-title":"J Neurosci"},{"issue":"1","key":"12148_CR40","doi-asserted-by":"publisher","first-page":"5154","DOI":"10.1038\/s41467-025-60293-4","volume":"16","author":"WC Liu","year":"2025","unstructured":"Liu WC, Wei YH, Chen JF, Xing XL, Jia HX, Yang XY, Huang YJ, Liu XM, Xiao K, Guo XD, Can C, Zhang AM, He N, Zhang HL (2025) Ma D. X. Inhibition of tumor-intrinsic NAT10 enhances antitumor immunity by triggering type I interferon response via MYC\/CDK2\/DNMT1 pathway. Nat Commun 16(1):5154","journal-title":"Nat Commun"},{"issue":"5","key":"12148_CR41","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1038\/s41422-023-00793-4","volume":"33","author":"L Liao","year":"2023","unstructured":"Liao L, He Y, Li SJ, Yu XM, Liu ZC, Liang YY, Yang H, Yang J, Zhang GG, Deng CM, Wei X, Zhu YD, Xu TY, Zheng CC, Cheng C, Li A, Li ZG, Liu JB, Li B (2023) Lysine 2-hydroxyisobutyrylation of NAT10 promotes cancer metastasis in an ac4C-dependent manner. Cell Res 33(5):355\u2013371","journal-title":"Cell Res"},{"issue":"19","key":"12148_CR42","doi-asserted-by":"publisher","first-page":"10896","DOI":"10.1093\/nar\/gkac594","volume":"50","author":"L Chen","year":"2022","unstructured":"Chen L, Wang WJ, Liu Q, Wu YK, Wu YW, Jiang Y, Liao XQ, Huang F, Li Y, Shen L, Yu C, Zhang SY, Yan LY, Qiao J, Sha QQ, Fan H (2022) Y. NAT10-mediated N4-acetylcytidine modification is required for meiosis entry and progression in male germ cells. Nucleic Acids Res 50(19):10896\u201310913","journal-title":"Nucleic Acids Res"},{"issue":"4","key":"12148_CR43","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1038\/s41418-021-00899-5","volume":"29","author":"J Zheng","year":"2022","unstructured":"Zheng J, Tan Y, Liu X, Zhang C, Su K, Jiang Y, Luo J, Li L, Du X (2022) NAT10 regulates mitotic cell fate by acetylating Eg5 to control bipolar spindle assembly and chromosome segregation. Cell Death Differ 29(4):846\u2013860","journal-title":"Cell Death Differ"},{"key":"12148_CR44","doi-asserted-by":"crossref","unstructured":"Wang Q, Yuan Y, Zhou Q, Jia Y, Liu J, Xiao G, Li C, Jiang X (2020) RNA N4-acetylcytidine modification and its role in health and diseases. MedComm 2025, 6(1): e70015","DOI":"10.1002\/mco2.70015"},{"key":"12148_CR45","doi-asserted-by":"publisher","first-page":"118191","DOI":"10.1016\/j.jep.2024.118191","volume":"330","author":"D Xiao","year":"2024","unstructured":"Xiao D, Huang S, Tang Z, Liu M, Di D, Ma Y, Li Y, Duan JA, Lu C, Zhao M (2024) Mijiao formula regulates NAT10-mediated Runx2 mRNA ac4C modification to promote bone marrow mesenchymal stem cell osteogenic differentiation and improve osteoporosis in ovariectomized rats. J Ethnopharmacol 330:118191","journal-title":"J Ethnopharmacol"},{"issue":"4","key":"12148_CR46","doi-asserted-by":"publisher","first-page":"e13577","DOI":"10.1111\/cpr.13577","volume":"57","author":"J Ge","year":"2024","unstructured":"Ge J, Wang Z, Wu J (2024) NAT10-mediated ac(4)C modification promotes ectoderm differentiation of human embryonic stem cells via acetylating NR2F1 mRNA. Cell Prolif 57(4):e13577","journal-title":"Cell Prolif"},{"issue":"1","key":"12148_CR47","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1186\/s13073-025-01520-x","volume":"17","author":"X Peng","year":"2025","unstructured":"Peng X, Li P, Zhang Y, Zhang Q, Liang W (2025) Aging increases susceptibility to liver fibrosis through enhanced NAT10-mediated ac4C modification of TGF\u03b21 mRNA. Genome Med 17(1):90","journal-title":"Genome Med"},{"key":"12148_CR48","doi-asserted-by":"crossref","unstructured":"Larrieu D, Vir\u00e9 E, Robson S, Breusegem SY, Kouzarides T, Jackson SP (2018) Inhibition of the acetyltransferase NAT10 normalizes progeric and aging cells by rebalancing the Transportin-1 nuclear import pathway. Sci Signal 11(537)","DOI":"10.1126\/scisignal.aar5401"},{"issue":"186","key":"12148_CR49","doi-asserted-by":"publisher","first-page":"1334","DOI":"10.24976\/Discov.Med.202436186.123","volume":"36","author":"T Cai","year":"2024","unstructured":"Cai T, Lin Y, Meng W (2024) A review of research on the mechanism of tumor regulation by N-acetyltransferase 10. Discov Med 36(186):1334\u20131344","journal-title":"Discov Med"},{"issue":"18","key":"12148_CR50","doi-asserted-by":"publisher","first-page":"9601","DOI":"10.1093\/nar\/gky777","volume":"46","author":"X Liu","year":"2018","unstructured":"Liu X, Cai S, Zhang C, Liu Z, Luo J, Xing B, Du X (2018) Deacetylation of NAT10 by Sirt1 promotes the transition from rRNA biogenesis to autophagy upon energy stress. Nucleic Acids Res 46(18):9601\u20139616","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"12148_CR51","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s13046-022-02586-w","volume":"42","author":"M Deng","year":"2023","unstructured":"Deng M, Zhang L, Zheng W, Chen J, Du N, Li M, Chen W, Huang Y, Zeng N, Song Y, Chen Y (2023) Helicobacter pylori-induced NAT10 stabilizes MDM2 mRNA via RNA acetylation to facilitate gastric cancer progression. J Exp Clin Cancer Res 42(1):9","journal-title":"J Exp Clin Cancer Res"},{"issue":"11","key":"12148_CR52","doi-asserted-by":"publisher","first-page":"e70934","DOI":"10.1002\/cam4.70934","volume":"14","author":"T Hara","year":"2025","unstructured":"Hara T, Meng S, Arao Y, Saito Y, Inoue K, Rennie S, Ofusa K, Kitagawa T, Ishii H (2025) Recent findings in N6-methyladenosine modification and significance in pancreatic cancer. Cancer Med 14(11):e70934","journal-title":"Cancer Med"},{"issue":"1","key":"12148_CR53","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/s43556-023-00139-x","volume":"4","author":"L Qiu","year":"2023","unstructured":"Qiu L, Jing Q, Li Y, Han J (2023) RNA modification: mechanisms and therapeutic targets. Mol Biomed 4(1):25","journal-title":"Mol Biomed"},{"issue":"1","key":"12148_CR54","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1038\/s41419-025-07656-3","volume":"16","author":"A Song","year":"2025","unstructured":"Song A, Liu B, Li W, Chen B, Gui P, Zhang H, Zhu C, Xu Y, Jiang T, Song J (2025) Competitive binding between DDX21 and SIRT7 enhances NAT10-mediated ac(4)C modification to promote colorectal cancer metastasis and angiogenesis- DDX21 promotes colorectal cancer metastasis. Cell Death Dis 16(1):353","journal-title":"Cell Death Dis"},{"issue":"10","key":"12148_CR55","doi-asserted-by":"publisher","first-page":"1666","DOI":"10.1158\/0008-5472.CAN-22-2233","volume":"83","author":"R Xie","year":"2023","unstructured":"Xie R, Cheng L, Huang M, Huang L, Chen Z, Zhang Q, Li H, Lu J, Wang H, Zhou Q, Huang J, Chen X, Lin T (2023) NAT10 Drives Cisplatin chemoresistance by enhancing ac4C-associated DNA repair in bladder cancer. Cancer Res 83(10):1666\u20131683","journal-title":"Cancer Res"},{"key":"12148_CR56","doi-asserted-by":"publisher","first-page":"704341","DOI":"10.3389\/fcell.2021.704341","volume":"9","author":"Y Xiang","year":"2021","unstructured":"Xiang Y, Zhou C, Zeng Y, Guo Q, Huang J, Wu T, Liu J, Liang Q, Zeng H (2021) Liang X. NAT10-mediated N4-acetylcytidine of RNA contributes to post-transcriptional regulation of mouse oocyte maturation in vitro. Front Cell Dev Biol 9:704341","journal-title":"Front Cell Dev Biol"},{"issue":"1","key":"12148_CR57","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1007\/s00401-024-02790-2","volume":"148","author":"P Botella Lucena","year":"2024","unstructured":"Botella Lucena P, Heneka MT (2024) Inflammatory aspects of Alzheimer\u2019s disease. Acta Neuropathol 148(1):31","journal-title":"Acta Neuropathol"},{"issue":"1","key":"12148_CR58","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1186\/s13578-025-01389-8","volume":"15","author":"HN Ji","year":"2025","unstructured":"Ji HN, Zhou HQ, Qie JB, Lu WM, Gao HT, Wu DH (2025) Dysregulated ac4C modification of mRNA in a mouse model of early-stage Alzheimer\u2019s disease. Cell Biosci 15(1):45","journal-title":"Cell Biosci"},{"issue":"4","key":"12148_CR59","doi-asserted-by":"publisher","first-page":"1659","DOI":"10.3233\/JAD-220564","volume":"90","author":"Y Ma","year":"2022","unstructured":"Ma Y, Li W, Fan C, Wang Y, Jiang H, Yang W (2022) Comprehensive analysis of long non-coding RNAs N4-acetylcytidine in alzheimer\u2019s disease mice model using high-throughput sequencing. J Alzheimers Dis 90(4):1659\u20131675","journal-title":"J Alzheimers Dis"},{"key":"12148_CR60","doi-asserted-by":"crossref","unstructured":"Yang Y, Chen C, Feng Y, Lv Q (2026) NAT10 and ac4C modification in cancer immunity and metabolism: emerging mechanisms and therapeutic potential. J Transl Med, 24(1):405","DOI":"10.1186\/s12967-026-07788-w"},{"issue":"38","key":"12148_CR61","doi-asserted-by":"publisher","first-page":"2868","DOI":"10.1038\/s41388-024-03133-x","volume":"43","author":"S Gong","year":"2024","unstructured":"Gong S, Qiao H, Wang JY, Huang SY, He SW, Zhao Y, Tan XR, Ye ML, Li JY, Liang YL, Huang SW, Chen J, Zhu XH, Liu N, Li YQ (2024) Ac4C modification of lncRNA SIMALR promotes nasopharyngeal carcinoma progression through activating eEF1A2 to facilitate ITGB4\/ITGA6 translation. Oncogene 43(38):2868\u20132884","journal-title":"Oncogene"},{"key":"12148_CR62","doi-asserted-by":"crossref","unstructured":"Zhang LS, Dai Q, He C (2024) Acc Chem Res 57(1):47\u201358Base-Resolution Sequencing Methods for Whole-Transcriptome Quantification of mRNA Modifications","DOI":"10.1021\/acs.accounts.3c00532"},{"key":"12148_CR63","doi-asserted-by":"publisher","first-page":"110512","DOI":"10.1016\/j.cbpc.2026.110512","volume":"305","author":"P Maaldu","year":"2026","unstructured":"Maaldu P, Chen Y, Mao G, Zhao T, Wu X, Feng W, Yang L (2026) Cyhalothrin induced neurotoxicity via disrupting NF-\u03baB and L-glutamate signaling and functions in zebrafish (Danio rerio). Comp Biochem Physiol C Toxicol Pharmacol 305:110512","journal-title":"Comp Biochem Physiol C Toxicol Pharmacol"},{"key":"12148_CR64","doi-asserted-by":"publisher","first-page":"115933","DOI":"10.1016\/j.jep.2022.115933","volume":"303","author":"F Lin","year":"2023","unstructured":"Lin F, Zhang G, Yang X, Wang M, Wang R, Wan M, Wang J, Wu B, Yan T, Jia Y (2023) A network pharmacology approach and experimental validation to investigate the anticancer mechanism and potential active targets of ethanol extract of Wei-Tong-Xin against colorectal cancer through induction of apoptosis via PI3K\/AKT signaling pathway. J Ethnopharmacol 303:115933","journal-title":"J Ethnopharmacol"},{"issue":"2","key":"12148_CR65","doi-asserted-by":"publisher","first-page":"e70762","DOI":"10.1002\/cns.70762","volume":"32","author":"X Xie","year":"2026","unstructured":"Xie X, Du W, Zhang Y, Zhang X (2026) Targeting the SIRT1-NAT10-GABABR1 Axis: A Novel Epitranscriptomic Approach to Mitigate Sevoflurane-Induced Cognitive Impairment in Aging. CNS Neurosci Ther 32(2):e70762","journal-title":"CNS Neurosci Ther"},{"issue":"4","key":"12148_CR66","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1007\/s10266-023-00793-1","volume":"111","author":"Z Cui","year":"2023","unstructured":"Cui Z, Xu Y, Wu P, Lu Y, Tao Y, Zhou C, Cui R, Li J, Han R (2023) NAT10 promotes osteogenic differentiation of periodontal ligament stem cells by regulating VEGFA-mediated PI3K\/AKT signaling pathway through ac4C modification. Odontology 111(4):870\u2013882","journal-title":"Odontology"},{"issue":"1","key":"12148_CR67","doi-asserted-by":"publisher","first-page":"2371950","DOI":"10.1080\/19490976.2024.2371950","volume":"16","author":"KA Conn","year":"2024","unstructured":"Conn KA, Borsom EM, Cope EK (2024) Implications of microbe-derived \u0263-aminobutyric acid (GABA) in gut and brain barrier integrity and GABAergic signaling in Alzheimer\u2019s disease. Gut Microbes 16(1):2371950","journal-title":"Gut Microbes"},{"issue":"7","key":"12148_CR68","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1016\/j.neuron.2025.01.030","volume":"113","author":"D Bi","year":"2025","unstructured":"Bi D, Bao H, Yang X, Wu Z, Yang X, Xu G, Liu X, Wan Z, Liu J, He J, Wen L, Jing Y, Zhu R, Long Z, Rong Y, Wang D, Wang X, Xiong W, Huang G, Gao F, Shen Y (2025) BACE1-dependent cleavage of GABA(A) receptor contributes to neural hyperexcitability and disease progression in Alzheimer\u2019s disease. Neuron 113(7):1051\u20131064e1056","journal-title":"Neuron"},{"key":"12148_CR69","doi-asserted-by":"publisher","first-page":"648636","DOI":"10.3389\/fphar.2021.648636","volume":"12","author":"HZ Long","year":"2021","unstructured":"Long HZ, Cheng Y, Zhou ZW, Luo HY, Wen DD, Gao LC (2021) PI3K\/AKT signal pathway: a target of natural products in the prevention and treatment of alzheimer\u2019s disease and parkinson\u2019s disease. Front Pharmacol 12:648636","journal-title":"Front Pharmacol"},{"issue":"3","key":"12148_CR70","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1007\/s10142-023-01192-z","volume":"23","author":"Y Ma","year":"2023","unstructured":"Ma Y, Fan C, Wang Y, Li W, Jiang H, Yang W (2023) Comprehensive analysis of mRNAs in the cerebral cortex in APP\/PS1 double-transgenic mice with Alzheimer\u2019s disease based on high-throughput sequencing of N4-acetylcytidine. Funct Integr Genomics 23(3):267","journal-title":"Funct Integr Genomics"},{"issue":"9","key":"12148_CR71","doi-asserted-by":"publisher","first-page":"5184","DOI":"10.1007\/s12035-023-03409-5","volume":"60","author":"Z Liu","year":"2023","unstructured":"Liu Z, Xia Q, Zhao X, Zheng F, Xiao J, Ge F, Wang D, Gao X (2023) The landscape of m6a regulators in multiple brain regions of alzheimer\u2019s disease. Mol Neurobiol 60(9):5184\u20135198","journal-title":"Mol Neurobiol"},{"key":"12148_CR72","doi-asserted-by":"crossref","unstructured":"Shi H, Li Z, Zou Q, Yang H (2025) Research on RNA modification in disease diagnosis and prognostic biomarkers: current status and challenges. Brief Bioinform, 26(4):bbaf361","DOI":"10.1093\/bib\/bbaf361"},{"issue":"7","key":"12148_CR73","doi-asserted-by":"publisher","first-page":"e14188","DOI":"10.1111\/acel.14188","volume":"23","author":"M Wang","year":"2024","unstructured":"Wang M, Zhang J, Qiu J, Ma X, Xu C, Wu Q, Xing S, Chen X, Liu B (2024) Doxycycline decelerates aging in progeria mice. Aging Cell 23(7):e14188","journal-title":"Aging Cell"},{"issue":"6","key":"12148_CR74","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1021\/acsmedchemlett.0c00193","volume":"12","author":"JH Shrimp","year":"2021","unstructured":"Shrimp JH, Jing Y, Gamage ST, Nelson KM, Han J, Bryson KM, Montgomery DC, Thomas JM, Nance KD, Sharma S, Fox SD, Andressen T, Sinclair WR, Wu H, Allali-Hassani A, Senisterra G, Vedadi M, Lafontaine D, Dahlin JL, Marmorstein R, Walters MA, Meier JL (2021) Remodelin is a cryptic assay interference chemotype that does not inhibit NAT10-dependent cytidine acetylation. ACS Med Chem Lett 12(6):887\u2013892","journal-title":"ACS Med Chem Lett"},{"key":"12148_CR75","doi-asserted-by":"crossref","unstructured":"Kopcho S, Mcdew-White M, Naushad W, Mohan M, Okeoma CM (2023) SIV Infection Regulates Compartmentalization of Circulating Blood Plasma miRNAs within Extracellular Vesicles (EVs) and Extracellular Condensates (ECs) and Decreases EV-Associated miRNA-128. Viruses, 15(3):622","DOI":"10.3390\/v15030622"},{"issue":"1","key":"12148_CR76","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/s10565-024-09962-6","volume":"41","author":"B Xiao","year":"2024","unstructured":"Xiao B, Wu S, Tian Y, Huang W, Chen G, Luo D, Cai Y, Chen M, Zhang Y, Liu C, Zhao J, Li L (2024) Advances of NAT10 in diseases: insights from dual properties as protein and RNA acetyltransferase. Cell Biol Toxicol 41(1):17","journal-title":"Cell Biol Toxicol"},{"issue":"3","key":"12148_CR77","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1038\/s43587-025-00823-3","volume":"5","author":"Y Cai","year":"2025","unstructured":"Cai Y, Kanyo J, Wilson R, Bathla S, Cardozo PL, Tong L, Qin S, Fuentes LA, Pinheiro-De-Sousa I, Huynh T, Sun L, Mansuri MS, Tian Z, Gan HR, Braker A, Trinh HK, Huttner A, Lam TT, Petsalaki E, Brennand KJ, Nairn AC, Grutzendler J (2025) Subcellular proteomics and iPSC modeling uncover reversible mechanisms of axonal pathology in Alzheimer\u2019s disease. Nat Aging 5(3):504\u2013527","journal-title":"Nat Aging"},{"issue":"4","key":"12148_CR78","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1523\/JNEUROSCI.1920-20.2020","volume":"41","author":"E Prifti","year":"2021","unstructured":"Prifti E, Tsakiri EN, Vourkou E, Stamatakis G, Samiotaki M, Papanikolopoulou K (2021) The two cysteines of tau protein are functionally distinct and contribute differentially to its pathogenicity in vivo. J Neurosci 41(4):797\u2013810","journal-title":"J Neurosci"},{"key":"12148_CR79","doi-asserted-by":"publisher","first-page":"103145","DOI":"10.1016\/j.redox.2024.103145","volume":"72","author":"Z Qu","year":"2024","unstructured":"Qu Z, Pang X, Mei Z, Li Y, Zhang Y, Huang C, Liu K, Yu S, Wang C, Sun Z, Liu Y, Li X, Jia Y, Dong Y, Lu M, Ju T, Wu F, Huang M, Li N, Dou S, Jiang J, Dong X, Zhang Y, Li W, Yang B, Du W (2024) The positive feedback loop of the NAT10\/Mybbp1a\/p53 axis promotes cardiomyocyte ferroptosis to exacerbate cardiac I\/R injury. Redox Biol 72:103145","journal-title":"Redox Biol"},{"issue":"6","key":"12148_CR80","doi-asserted-by":"publisher","first-page":"678","DOI":"10.4103\/psychiatry.IndianJPsychiatry_783_19","volume":"62","author":"DH Abou-Elela","year":"2020","unstructured":"Abou-Elela DH, El-Edel RH, Shalaby AS, Fouaad MA, Sonbol AA (2020) Telomere length and 8-hydroxy-2-deoxyguanosine as markers for early prediction of Alzheimer disease. Indian J Psychiatry 62(6):678\u2013683","journal-title":"Indian J Psychiatry"},{"issue":"1","key":"12148_CR81","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1186\/s40478-020-01012-6","volume":"8","author":"KM Farmer","year":"2020","unstructured":"Farmer KM, Ghag G, Puangmalai N, Montalbano M, Bhatt N, Kayed R (2020) P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer\u2019s disease. Acta Neuropathol Commun 8(1):132","journal-title":"Acta Neuropathol Commun"},{"issue":"1","key":"12148_CR82","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1186\/s13195-020-00732-0","volume":"12","author":"G Abate","year":"2020","unstructured":"Abate G, Frisoni GB, Bourdon JC, Piccirella S, Memo M, Uberti D (2020) The pleiotropic role of p53 in functional\/dysfunctional neurons: focus on pathogenesis and diagnosis of Alzheimer\u2019s disease. Alzheimers Res Ther 12(1):160","journal-title":"Alzheimers Res Ther"},{"issue":"3","key":"12148_CR83","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1002\/cac2.12520","volume":"44","author":"B Song","year":"2024","unstructured":"Song B, Yang P, Zhang S (2024) Cell fate regulation governed by p53: Friends or reversible foes in cancer therapy. Cancer Commun (Lond) 44(3):297\u2013360","journal-title":"Cancer Commun (Lond)"},{"issue":"11","key":"12148_CR84","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1038\/s41580-024-00757-5","volume":"25","author":"RA Nixon","year":"2024","unstructured":"Nixon RA, Rubinsztein DC (2024) Mechanisms of autophagy-lysosome dysfunction in neurodegenerative diseases. Nat Rev Mol Cell Biol 25(11):926\u2013946","journal-title":"Nat Rev Mol Cell Biol"},{"key":"12148_CR85","doi-asserted-by":"publisher","first-page":"101464","DOI":"10.1016\/j.arr.2021.101464","volume":"72","author":"Z Zhang","year":"2021","unstructured":"Zhang Z, Yang X, Song YQ, Tu J (2021) Autophagy in Alzheimer\u2019s disease pathogenesis: Therapeutic potential and future perspectives. Ageing Res Rev 72:101464","journal-title":"Ageing Res Rev"},{"key":"12148_CR86","doi-asserted-by":"publisher","first-page":"919","DOI":"10.3389\/fonc.2020.00919","volume":"10","author":"RWJ Kaiser","year":"2020","unstructured":"Kaiser RWJ, Erber J, H\u00f6pker K, Fabretti F, M\u00fcller RU (2020) AATF\/Che-1-An RNA binding protein at the nexus of DNA damage response and ribosome biogenesis. Front Oncol 10:919","journal-title":"Front Oncol"},{"issue":"4","key":"12148_CR87","doi-asserted-by":"publisher","first-page":"1520","DOI":"10.1002\/hep.30346","volume":"69","author":"DP Kumar","year":"2019","unstructured":"Kumar DP, Santhekadur PK, Seneshaw M, Mirshahi F, Uram-Tuculescu C, Sanyal AJ (2019) A regulatory role of apoptosis antagonizing transcription factor in the pathogenesis of nonalcoholic fatty liver disease and hepatocellular carcinoma. Hepatology 69(4):1520\u20131534","journal-title":"Hepatology"},{"key":"12148_CR88","doi-asserted-by":"publisher","first-page":"109716","DOI":"10.1016\/j.neuropharm.2023.109716","volume":"240","author":"ZJ Wang","year":"2023","unstructured":"Wang ZJ, Li XR, Chai SF, Li WR, Li S, Hou M, Li JL, Ye YC, Cai HY, H\u00f6lscher C (2023) Wu M. N. Semaglutide ameliorates cognition and glucose metabolism dysfunction in the 3xTg mouse model of Alzheimer\u2019s disease via the GLP-1R\/SIRT1\/GLUT4 pathway. Neuropharmacology 240:109716","journal-title":"Neuropharmacology"},{"issue":"6","key":"12148_CR89","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.24272\/j.issn.2095-8137.2023.294","volume":"44","author":"XW Zhang","year":"2023","unstructured":"Zhang XW, Zhu XX, Tang DS, Lu JH (2023) Targeting autophagy in Alzheimer\u2019s disease: Animal models and mechanisms. Zool Res 44(6):1132\u20131145","journal-title":"Zool Res"},{"issue":"1","key":"12148_CR90","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1186\/s12974-022-02565-0","volume":"19","author":"D Singh","year":"2022","unstructured":"Singh D (2022) Astrocytic and microglial cells as the modulators of neuroinflammation in Alzheimer\u2019s disease. J Neuroinflammation 19(1):206","journal-title":"J Neuroinflammation"},{"issue":"1","key":"12148_CR91","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1038\/s42003-022-03868-x","volume":"5","author":"H Zhang","year":"2022","unstructured":"Zhang H, Chen Z, Zhou J, Gu J, Wu H, Jiang Y, Gao S, Liao Y, Shen R, Miao C, Chen W (2022) NAT10 regulates neutrophil pyroptosis in sepsis via acetylating ULK1 RNA and activating STING pathway. Commun Biol 5(1):916","journal-title":"Commun Biol"},{"issue":"7","key":"12148_CR92","doi-asserted-by":"publisher","first-page":"119521","DOI":"10.1016\/j.bbamcr.2023.119521","volume":"1870","author":"Z Zhang","year":"2023","unstructured":"Zhang Z, Zhang Y, Cai Y, Li D, He J, Feng Z, Xu Q (2023) NAT10 regulates the LPS-induced inflammatory response via the NOX2-ROS-NF-\u03baB pathway in macrophages [J]. Biochim Biophys Acta Mol Cell Res 1870(7):119521","journal-title":"Biochim Biophys Acta Mol Cell Res"},{"issue":"2","key":"12148_CR93","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/j.immuni.2025.01.007","volume":"58","author":"RM Mcmanus","year":"2025","unstructured":"Mcmanus RM, Komes MP, Griep A, Santarelli F, Schwartz S, Ram\u00f3n Perea J, Schlachetzki JCM, Bouvier DS, Khalil MA, Lauterbach MA, Heinemann L, Schl\u00fcter T, Pour MS, Lovotti M, Stahl R, Duthie F, Rodr\u00edguez-Alc\u00e1zar JF, Schmidt SV, Spitzer J, Noori P, Maillo A, Boettcher A, Herron B, Mcconville J, Gomez-Cabrero D, Tegn\u00e9r J, Glass CK, Hiller K, Latz E, Heneka MT (2025) NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer\u2019s disease progression. Immunity 58(2):326\u2013343e311","journal-title":"Immunity"},{"issue":"8","key":"12148_CR94","doi-asserted-by":"publisher","first-page":"2691","DOI":"10.1093\/brain\/awae113","volume":"147","author":"V Gomez-Murcia","year":"2024","unstructured":"Gomez-Murcia V, Launay A, Carvalho K, Burgard A, Meriaux C, Caillierez R, Eddarkaoui S, Kilinc D, Siedlecki-Wullich D, Besegher M, B\u00e9gard S, Thiroux B, Jung M, Nebie O, Wisztorski M, D\u00e9glon N, Montmasson C, Bemelmans AP, Hamdane M, Lebouvier T, Vieau D, Fournier I, Buee L, L\u00e9vi S, Lopes LV, Boutillier AL, Faivre E, Blum D (2024) Neuronal A2A receptor exacerbates synapse loss and memory deficits in APP\/PS1 mice. Brain 147(8):2691\u20132705","journal-title":"Brain"},{"key":"12148_CR95","doi-asserted-by":"publisher","first-page":"462422","DOI":"10.1016\/j.chroma.2021.462422","volume":"1653","author":"J Lyu","year":"2021","unstructured":"Lyu J, Li H, Yin D, Zhao M, Sun Q, Guo M (2021) Analysis of eight bile acids in urine of gastric cancer patients based on covalent organic framework enrichment coupled with liquid chromatography-tandem mass spectrometry. J Chromatogr A 1653:462422","journal-title":"J Chromatogr A"},{"issue":"1","key":"12148_CR96","doi-asserted-by":"publisher","first-page":"3577","DOI":"10.1038\/s41598-024-54197-4","volume":"14","author":"J Gao","year":"2024","unstructured":"Gao J, Xu P, Wang F, Zhang W, Min M, Urba R, Fan L (2024) Revealing the pharmacological effects of Remodelin against osteosarcoma based on network pharmacology, acRIP-seq and experimental validation. Sci Rep 14(1):3577","journal-title":"Sci Rep"},{"issue":"1","key":"12148_CR97","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1038\/s41392-022-01175-9","volume":"7","author":"L Cui","year":"2022","unstructured":"Cui L, Ma R, Cai J, Guo C, Chen Z, Yao L, Wang Y, Fan R, Wang X, Shi Y (2022) RNA modifications: importance in immune cell biology and related diseases. Signal Transduct Target Ther 7(1):334","journal-title":"Signal Transduct Target Ther"},{"key":"12148_CR98","doi-asserted-by":"publisher","first-page":"108576","DOI":"10.1016\/j.pharmthera.2023.108576","volume":"253","author":"Y Zhang","year":"2024","unstructured":"Zhang Y, Lei Y, Dong Y, Chen S, Sun S, Zhou F, Zhao Z, Chen B, Wei L, Chen J, Meng Z (2024) Emerging roles of RNA ac4C modification and NAT10 in mammalian development and human diseases. Pharmacol Ther 253:108576","journal-title":"Pharmacol Ther"},{"key":"12148_CR99","doi-asserted-by":"crossref","unstructured":"Thalalla Gamage S, Howpay Manage S, Sas-Chen A, Nir R, Burkhart BW, Jhulki I, Link CN, Penikalapati MS, Jones JE, Iyer LM, Aravind L, Santangelo TJ, Schwartz S, Meier J (2025) L. A sequence-specific RNA acetylation catalyst. Nucleic Acids Res, 53(6):gkaf217","DOI":"10.1093\/nar\/gkaf217"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-026-12148-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11033-026-12148-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-026-12148-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T15:03:04Z","timestamp":1781881384000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11033-026-12148-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,19]]},"references-count":99,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["12148"],"URL":"https:\/\/doi.org\/10.1007\/s11033-026-12148-4","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,19]]},"assertion":[{"value":"11 April 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 June 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 June 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"968"}}