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During the initial drafting and framework organization stage, generative AI tools were only used for three auxiliary purposes: logical sorting of PI4K\/PIPK signalling pathway frameworks, standardization of drawing specification rules, and preliminary English language polishing of the manuscript text. No generative AI tools were used to directly generate any original graphical elements, cellular structures, molecular icons, pathway arrows or layout designs in the final submitted figures. All final schematic diagrams have been completely manually reconstructed, and all pathway logic, molecular nomenclature, regulatory arrow rules and formatting standards have been uniformly verified and proofread by all authors.","order":3,"name":"Ethics","label":"Generative AI Usage and Figure Preparation Statement","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":4,"name":"Ethics","label":"Patient consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"1165"}}