{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T13:59:46Z","timestamp":1790085586210,"version":"4.0.1"},"reference-count":57,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:00:00Z","timestamp":1787961600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:00:00Z","timestamp":1787961600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["ITMS: 313011AUA4"],"award-info":[{"award-number":["ITMS: 313011AUA4"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1007\/s11033-026-12632-x","type":"journal-article","created":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T10:55:42Z","timestamp":1788000942000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Preliminary miRNA profiling of plasma from patients infected with distinct SARS-CoV-2 variants"],"prefix":"10.1007","volume":"53","author":[{"given":"Ivana","family":"Baranova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Dvorska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Kapinova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4912-8754","authenticated-orcid":false,"given":"Dusan","family":"Brany","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Samec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Baranovicova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronika","family":"Holubekova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuzana","family":"Kolkova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Skerenova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dusan","family":"Loderer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Novakova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Halasova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Liptak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Banovcin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Bobcakova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Rosolanka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuzana","family":"Dankova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,29]]},"reference":[{"issue":"7","key":"12632_CR1","doi-asserted-by":"publisher","first-page":"e252223","DOI":"10.1001\/jamahealthforum.2025.2223","volume":"6","author":"JPA Ioannidis","year":"2025","unstructured":"Ioannidis JPA, Pezzullo AM, Cristiano A, Boccia S (2025) Global Estimates of Lives and Life-Years Saved by COVID-19 Vaccination During 2020\u20132024. JAMA Health Forum 6(7):e252223","journal-title":"JAMA Health Forum"},{"issue":"1","key":"12632_CR2","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1186\/s12879-025-10817-6","volume":"25","author":"JR Arribas L\u00f3pez","year":"2025","unstructured":"Arribas L\u00f3pez JR, Ruiz Seco MP, Fanjul F, D\u00edaz Poll\u00e1n B, Gonz\u00e1lez Ruano P\u00e9rez P, Ferre Beltr\u00e1n A et al (2025) Remdesivir associated with reduced mortality in hospitalized COVID-19 patients: treatment effectiveness using real-world data and natural language processing. BMC Infect Dis 25(1):513","journal-title":"BMC Infect Dis"},{"issue":"4","key":"12632_CR3","doi-asserted-by":"publisher","first-page":"803","DOI":"10.3390\/biomedicines13040803","volume":"13","author":"M Queipo","year":"2025","unstructured":"Queipo M, Mateo J, Torres AM, Barbado J (2025) The Effect of Naturally Acquired Immunity on Mortality Predictors: A Focus on Individuals with New Coronavirus. Biomedicines 13(4):803","journal-title":"Biomedicines"},{"issue":"5","key":"12632_CR4","doi-asserted-by":"publisher","first-page":"104688","DOI":"10.1016\/j.idnow.2023.104688","volume":"53","author":"A Hern\u00e1ndez-Aceituno","year":"2023","unstructured":"Hern\u00e1ndez-Aceituno A, Garc\u00eda-Hern\u00e1ndez A, Larumbe-Zabala E (2023) COVID-19 long-term sequelae: Omicron versus Alpha and Delta variants. Infect Dis Now 53(5):104688","journal-title":"Infect Dis Now"},{"issue":"1","key":"12632_CR5","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/S1473-3099(21)00475-8","volume":"22","author":"KA Twohig","year":"2022","unstructured":"Twohig KA, Nyberg T, Zaidi A, Thelwall S, Sinnathamby MA, Aliabadi S et al (2022) Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study. Lancet Infect Dis 22(1):35\u201342","journal-title":"Lancet Infect Dis"},{"issue":"7","key":"12632_CR6","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1016\/j.cmi.2023.03.017","volume":"29","author":"FH Hu","year":"2023","unstructured":"Hu FH, Jia YJ, Zhao DY, Fu XL, Zhang WQ, Tang W et al (2023) Clinical outcomes of the severe acute respiratory syndrome coronavirus 2 Omicron and Delta variant: systematic review and meta-analysis of 33 studies covering 6 037 144 coronavirus disease 2019-positive patients. Clin Microbiol Infect 29(7):835\u2013844","journal-title":"Clin Microbiol Infect"},{"issue":"1","key":"12632_CR7","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1038\/s41467-022-28089-y","volume":"13","author":"B Li","year":"2022","unstructured":"Li B, Deng A, Li K, Hu Y, Li Z, Shi Y et al (2022) Viral infection and transmission in a large, well-traced outbreak caused by the SARS-CoV-2 Delta variant. Nat Commun 13(1):460","journal-title":"Nat Commun"},{"issue":"2","key":"12632_CR8","doi-asserted-by":"publisher","first-page":"31","DOI":"10.37737\/ace.23005","volume":"5","author":"K Uemura","year":"2023","unstructured":"Uemura K, Kanata T, Ono S, Michihata N, Yasunaga H (2023) The disease severity of COVID-19 caused by Omicron variants: A brief review. Ann Clin Epidemiol 5(2):31\u201336","journal-title":"Ann Clin Epidemiol"},{"issue":"2","key":"12632_CR9","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1002\/med.22073","volume":"45","author":"SZ Bahojb Mahdavi","year":"2025","unstructured":"Bahojb Mahdavi SZ, Jebelli A, Aghbash PS, Baradaran B, Amini M, Oroojalian F et al (2025) A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection. Med Res Rev 45(2):349\u2013425","journal-title":"Med Res Rev"},{"key":"12632_CR10","unstructured":"Coco E, Vanni I (2019) Exosome miRNAProfiling with the Agilent miRNA Microarray Platform (Application Note). Retrieved from Agilent website: https:\/\/www.agilent.com\/cs\/library\/applications\/5994-0777EN.pdf"},{"issue":"W1","key":"12632_CR11","doi-asserted-by":"publisher","first-page":"W409","DOI":"10.1093\/nar\/gkab297","volume":"49","author":"F Kern","year":"2021","unstructured":"Kern F, Aparicio-Puerta E, Li Y, Fehlmann T, Kehl T, Wagner V et al (2021) miRTargetLink 2.0\u2014interactive miRNA target gene and target pathway networks. Nucleic Acids Res 49(W1):W409\u2013W416","journal-title":"Nucleic Acids Res"},{"issue":"D1","key":"12632_CR12","doi-asserted-by":"publisher","first-page":"D607","DOI":"10.1093\/nar\/gky1131","volume":"47","author":"D Szklarczyk","year":"2019","unstructured":"Szklarczyk D, Gable AL, Lyon D, Junge A, Wyder S, Huerta-Cepas J et al (2019) STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets. Nucleic Acids Res 47(D1):D607\u2013D613","journal-title":"Nucleic Acids Res"},{"key":"12632_CR13","doi-asserted-by":"publisher","unstructured":"Alipoor SD, Mortaz E, Jamaati H, Tabarsi P, Bayram H, Varahram M et al COVID-19: Molecular and Cellular Response. Front Cell Infect Microbiol [Internet]. 2021 Feb 11 [cited 2025 Nov 5];11. Available from: https:\/\/www.frontiersin.org\/journals\/cellular-and-infection-microbiology\/articles\/https:\/\/doi.org\/10.3389\/fcimb.2021.563085\/full","DOI":"10.3389\/fcimb.2021.563085\/full"},{"key":"12632_CR14","doi-asserted-by":"publisher","first-page":"11997","DOI":"10.3389\/av.2023.11997","volume":"67","author":"Z Klestova","year":"2023","unstructured":"Klestova Z (2023) The effects of SARS-CoV-2 on susceptible human cells. Acta Virol 67:11997","journal-title":"Acta Virol"},{"issue":"11","key":"12632_CR15","doi-asserted-by":"publisher","first-page":"2270","DOI":"10.3201\/eid2811.220577","volume":"28","author":"AM Quintero","year":"2022","unstructured":"Quintero AM, Eisner M, Sayegh R, Wright T, Ramilo O, Leber AL et al (2022) Differences in SARS-CoV-2 Clinical Manifestations and Disease Severity in Children and Adolescents by Infecting Variant. Emerg Infect Dis 28(11):2270\u20132280","journal-title":"Emerg Infect Dis"},{"key":"12632_CR16","doi-asserted-by":"publisher","first-page":"198853","DOI":"10.1016\/j.virusres.2022.198853","volume":"318","author":"S Bhat","year":"2022","unstructured":"Bhat S, Rishi P, Chadha VD (2022) Understanding the epigenetic mechanisms in SARS CoV-2 infection and potential therapeutic approaches. Virus Res 318:198853","journal-title":"Virus Res"},{"key":"12632_CR17","doi-asserted-by":"crossref","unstructured":"Han Y, Zhang G, Lv X, Ren L (2025) Critical role of cellular microRNAs in virus infection: Decades of progress. Animals and Zoonoses [Internet]. Jan 13 [cited 2025 Nov 9]; Available from: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2950248925000021","DOI":"10.1016\/j.azn.2025.01.002"},{"issue":"6","key":"12632_CR18","doi-asserted-by":"publisher","first-page":"7204","DOI":"10.18632\/oncotarget.23208","volume":"9","author":"L Chen","year":"2018","unstructured":"Chen L, Deng H, Cui H, Fang J, Zuo Z, Deng J et al (2018) Inflammatory responses and inflammation-associated diseases in organs. Oncotarget 9(6):7204\u20137218","journal-title":"Oncotarget"},{"key":"12632_CR19","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1186\/s12950-024-00417-7","volume":"21","author":"H Bannazadeh Baghi","year":"2024","unstructured":"Bannazadeh Baghi H, Bayat M, Mehrasa P, Alavi SMA, Lotfalizadeh MH, Memar MY et al (2024) Regulatory role of microRNAs in virus-mediated inflammation. J Inflamm (Lond) 21:43","journal-title":"J Inflamm (Lond)"},{"key":"12632_CR20","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1186\/s12964-024-01601-1","volume":"22","author":"T Wang","year":"2024","unstructured":"Wang T, Song D, Li X, Luo Y, Yang D, Liu X et al (2024) MiR-574-5p activates human TLR8 to promote autoimmune signaling and lupus. Cell Commun Signal 22:220","journal-title":"Cell Commun Signal"},{"key":"12632_CR21","doi-asserted-by":"publisher","unstructured":"Han M, Chen Z, He P, Li Z, Chen Q, Tong Z et al (2022) YgiM may act as a trigger in the sepsis caused by Klebsiella pneumoniae through the membrane-associated ceRNA network. Front Genet [Internet]. Sep 23 [cited 2025 Nov 10];13. Available from: https:\/\/www.frontiersin.org\/journals\/genetics\/articles\/https:\/\/doi.org\/10.3389\/fgene.2022.973145\/full","DOI":"10.3389\/fgene.2022.973145\/full"},{"issue":"1","key":"12632_CR22","doi-asserted-by":"publisher","first-page":"125","DOI":"10.7150\/thno.78164","volume":"13","author":"Y Liang","year":"2023","unstructured":"Liang Y, Fang D, Gao X, Deng X, Chen N, Wu J et al (2023) Circulating microRNAs as emerging regulators of COVID-19. Theranostics 13(1):125\u2013147","journal-title":"Theranostics"},{"issue":"2","key":"12632_CR23","first-page":"111","volume":"2","author":"F Talebi","year":"2020","unstructured":"Talebi F, Ghourbani S, Vojgani M, Noorbakhsh F (2020) miR-320 and Inflammation Regulation in Experimental Autoimmune Encephalomyelitis Through Interference With Tumor Growth Factor-\u03b2 Signaling Pathway. Immunoregulation 2(2):111\u2013120","journal-title":"Immunoregulation"},{"issue":"3","key":"12632_CR24","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1016\/j.immuni.2021.02.015","volume":"54","author":"Y Mikami","year":"2021","unstructured":"Mikami Y, Philips RL, Scium\u00e8 G, Petermann F, Meylan F, Nagashima H et al (2021) MicroRNA-221 and \u2013\u2009222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of Interleukin-23. Immunity 54(3):514\u2013525e6","journal-title":"Immunity"},{"issue":"2","key":"12632_CR25","first-page":"981","volume":"19","author":"X Lu","year":"2020","unstructured":"Lu X, Yu Y, Tan S (2020) The role of the miR-21-5p-mediated inflammatory pathway in ulcerative colitis. Exp Ther Med 19(2):981\u2013989","journal-title":"Exp Ther Med"},{"issue":"6","key":"12632_CR26","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1038\/s41418-021-00911-y","volume":"29","author":"SJ Hwang","year":"2022","unstructured":"Hwang SJ, Ahn BJ, Shin MW, Song YS, Choi Y, Oh GT et al (2022) miR-125a-5p attenuates macrophage-mediated vascular dysfunction by targeting Ninjurin1. Cell Death Differ 29(6):1199\u20131210","journal-title":"Cell Death Differ"},{"issue":"11","key":"12632_CR27","doi-asserted-by":"publisher","first-page":"934","DOI":"10.5152\/tjg.2022.21769","volume":"33","author":"F Xia","year":"2022","unstructured":"Xia F, Bo W, Ding J, Yu Y, Wang J (2022) MiR-222-3p Aggravates the Inflammatory Response by Targeting SOCS1 to Activate STAT3 Signaling in Ulcerative Colitis. Turk J Gastroenterol 33(11):934\u2013944","journal-title":"Turk J Gastroenterol"},{"key":"12632_CR28","doi-asserted-by":"publisher","first-page":"6182464","DOI":"10.1155\/2020\/6182464","volume":"2020","author":"H Nie","year":"2020","unstructured":"Nie H, Hu Y, Guo W, Wang W, Yang Q, Dong Q et al (2020) miR-331-3p Inhibits Inflammatory Response after Intracerebral Hemorrhage by Directly Targeting NLRP6. Biomed Res Int 2020:6182464","journal-title":"Biomed Res Int"},{"key":"12632_CR29","doi-asserted-by":"publisher","first-page":"903","DOI":"10.2147\/DMSO.S449791","volume":"17","author":"C Xing","year":"2024","unstructured":"Xing C, Lu Y, Liu G, Chen F, Hou Z, Zhang Y (2024) The Expression of miR-377-3p in Patients with DKD and the Regulatory Mechanism of miR-377-3p on the Inflammatory Response of HK-2 Cells Through TGF-\u03b2. Diabetes Metab Syndr Obes 17:903\u2013911","journal-title":"Diabetes Metab Syndr Obes"},{"issue":"2","key":"12632_CR30","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1093\/bbb\/zbaa009","volume":"85","author":"M Xu","year":"2021","unstructured":"Xu M, Li XY, Song L, Tao C, Fang J, Tao L (2021) miR-484 targeting of Yap1-induced LPS-inhibited proliferation, and promoted apoptosis and inflammation in cardiomyocyte. Biosci Biotechnol Biochem 85(2):378\u2013385","journal-title":"Biosci Biotechnol Biochem"},{"issue":"12","key":"12632_CR31","doi-asserted-by":"publisher","first-page":"1844","DOI":"10.3390\/v16121844","volume":"16","author":"P Evers","year":"2024","unstructured":"Evers P, Uguccioni SM, Ahmed N, Francis ME, Kelvin AA, Pezacki JP (2024) miR-24-3p Is Antiviral Against SARS-CoV-2 by Downregulating Critical Host Entry Factors. Viruses 16(12):1844","journal-title":"Viruses"},{"key":"12632_CR32","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/s11658-022-00317-9","volume":"27","author":"A Letafati","year":"2022","unstructured":"Letafati A, Najafi S, Mottahedi M, Karimzadeh M, Shahini A, Garousi S et al (2022) MicroRNA let-7 and viral infections: focus on mechanisms of action. Cell Mol Biol Lett 27:14","journal-title":"Cell Mol Biol Lett"},{"issue":"4","key":"12632_CR33","doi-asserted-by":"publisher","first-page":"e1006305","DOI":"10.1371\/journal.ppat.1006305","volume":"13","author":"CM Rosenberger","year":"2017","unstructured":"Rosenberger CM, Podyminogin RL, Diercks AH, Treuting PM, Peschon JJ, Rodriguez D et al (2017) miR-144 attenuates the host response to influenza virus by targeting the TRAF6-IRF7 signaling axis. PLoS Pathog 13(4):e1006305","journal-title":"PLoS Pathog"},{"issue":"1","key":"12632_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/15476286.2021.2010959","volume":"19","author":"SM Akula","year":"2022","unstructured":"Akula SM, Bolin P, Cook PP (2022) Cellular miR-150-5p may have a crucial role to play in the biology of SARS-CoV-2 infection by regulating nsp10 gene. RNA Biol 19(1):1\u201311","journal-title":"RNA Biol"},{"issue":"2","key":"12632_CR35","doi-asserted-by":"publisher","first-page":"108198","DOI":"10.1016\/j.jbc.2025.108198","volume":"301","author":"A Dasgupta","year":"2025","unstructured":"Dasgupta A, Tripathi A, Mitra A, Ghosh P, Santra MK, Mitra D (2025) Human microRNA miR-197-3p positively regulates HIV-1 virion infectivity through its target DDX52 by stabilizing Vif protein expression. J Biol Chem 301(2):108198","journal-title":"J Biol Chem"},{"issue":"4","key":"12632_CR36","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1177\/0004563217741908","volume":"55","author":"X Shen","year":"2018","unstructured":"Shen X, Xue Y, Cong H, Wang X, Ju S (2018) Dysregulation of serum microRNA-574-3p and its clinical significance in hepatocellular carcinoma. Ann Clin Biochem 55(4):478\u2013484","journal-title":"Ann Clin Biochem"},{"issue":"12","key":"12632_CR37","doi-asserted-by":"publisher","first-page":"5157","DOI":"10.1093\/nar\/gkr067","volume":"39","author":"N Potenza","year":"2011","unstructured":"Potenza N, Papa U, Mosca N, Zerbini F, Nobile V, Russo A (2011) Human microRNA hsa-miR-125a-5p interferes with expression of hepatitis B virus surface antigen. Nucleic Acids Res 39(12):5157\u20135163","journal-title":"Nucleic Acids Res"},{"issue":"11","key":"12632_CR38","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.3390\/v12111207","volume":"12","author":"E Roy","year":"2020","unstructured":"Roy E, Byrareddy SN, Reid SP (2020) Role of MicroRNAs in Bone Pathology during Chikungunya Virus Infection. Viruses 12(11):1207","journal-title":"Viruses"},{"key":"12632_CR39","doi-asserted-by":"publisher","first-page":"143","DOI":"10.3389\/fcell.2020.00143","volume":"8","author":"MG Barbu","year":"2020","unstructured":"Barbu MG, Condrat CE, Thompson DC, Bugnar OL, Cretoiu D, Toader OD et al (2020) MicroRNA Involvement in Signaling Pathways During Viral Infection. Front Cell Dev Biol 8:143","journal-title":"Front Cell Dev Biol"},{"key":"12632_CR40","doi-asserted-by":"publisher","first-page":"107393","DOI":"10.1016\/j.intimp.2021.107393","volume":"93","author":"Y Wang","year":"2021","unstructured":"Wang Y, Jia X, Zhou L, Yin J, Zhao Y, Dai L et al (2021) Increased let-7b-5p is associated with enhanced BAFF-R expression and B cell survival in immune thrombocytopenia. Int Immunopharmacol 93:107393","journal-title":"Int Immunopharmacol"},{"issue":"4","key":"12632_CR41","doi-asserted-by":"publisher","first-page":"e13952","DOI":"10.1111\/pai.13952","volume":"34","author":"E Ahlberg","year":"2023","unstructured":"Ahlberg E, Mart\u00ed M, Govindaraj D, Severin E, Duch\u00e9n K, Jenmalm MC et al (2023) Immune-related microRNAs in breast milk and their relation to regulatory T cells in breastfed children. Pediatr Allergy Immunol 34(4):e13952","journal-title":"Pediatr Allergy Immunol"},{"key":"12632_CR42","doi-asserted-by":"publisher","first-page":"110415","DOI":"10.1016\/j.cellsig.2022.110415","volume":"98","author":"S Regis","year":"2022","unstructured":"Regis S, Dondero A, Spaggiari GM, Serra M, Caliendo F, Bottino C et al (2022) miR-24-3p down-regulates the expression of the apoptotic factors FasL and BIM in human natural killer cells. Cell Signal 98:110415","journal-title":"Cell Signal"},{"issue":"4","key":"12632_CR43","doi-asserted-by":"publisher","first-page":"100433","DOI":"10.1016\/j.jgeb.2024.100433","volume":"22","author":"S Salem","year":"2024","unstructured":"Salem S, Lotfy R, Eltaweel N, Elbadry M (2024) Association of plasma microRNAs with COVID-19 severity and outcome. J Genetic Eng Biotechnol 22(4):100433","journal-title":"J Genetic Eng Biotechnol"},{"issue":"2","key":"12632_CR44","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1093\/cvr\/cvab338","volume":"118","author":"C Gutmann","year":"2021","unstructured":"Gutmann C, Khamina K, Theofilatos K, Diendorfer AB, Burnap SA, Nabeebaccus A et al (2021) Association of cardiometabolic microRNAs with COVID-19 severity and mortality. Cardiovasc Res 118(2):461\u2013474","journal-title":"Cardiovasc Res"},{"issue":"1","key":"12632_CR45","doi-asserted-by":"publisher","first-page":"17139","DOI":"10.1038\/s41598-025-01229-2","volume":"15","author":"E Pius-Sadowska","year":"2025","unstructured":"Pius-Sadowska E, Kulig P, Nied\u017awied\u017a A, Baumert B, Rogi\u0144ska D, \u0141uczkowska K et al (2025) The micro-RNA expression profile predicts the severity of SARS-CoV-2 infection. Sci Rep 15(1):17139","journal-title":"Sci Rep"},{"key":"12632_CR46","doi-asserted-by":"publisher","unstructured":"Xiang M, Li P, Yue X, Liu L, Wang L, Sun N et al Dysregulated macrophage immunity in Helicobacter pylori infection: unveiling mechanistic insights and therapeutic implications. Front Immunol [Internet]. 2025 Aug 4 [cited 2025 Nov 10];16. Available from: https:\/\/www.frontiersin.org\/journals\/immunology\/articles\/https:\/\/doi.org\/10.3389\/fimmu.2025.1636768\/full","DOI":"10.3389\/fimmu.2025.1636768\/full"},{"issue":"3","key":"12632_CR47","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.4049\/jimmunol.1700196","volume":"200","author":"Y Zhang","year":"2018","unstructured":"Zhang Y, Liu W, Chen Y, Liu J, Wu K, Su L et al (2018) A Cellular MicroRNA Facilitates Regulatory T Lymphocyte Development by Targeting the FOXP3 Promoter TATA-Box Motif. J Immunol 200(3):1053\u20131063","journal-title":"J Immunol"},{"issue":"5","key":"12632_CR48","doi-asserted-by":"publisher","first-page":"334","DOI":"10.3892\/mmr.2022.12850","volume":"26","author":"X Xu","year":"2022","unstructured":"Xu X, Bu B, Tian H, Wu R, Yang J (2022) MicroRNAs combined with the TLR4\/TDAG8 mRNAs and proinflammatory cytokines are biomarkers for the rapid diagnosis of sepsis. Mol Med Rep 26(5):334","journal-title":"Mol Med Rep"},{"issue":"1","key":"12632_CR49","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1186\/s12879-023-08714-x","volume":"23","author":"N Radhakrishnan","year":"2023","unstructured":"Radhakrishnan N, Liu M, Idowu B, Bansari A, Rathi K, Magar S et al (2023) Comparison of the clinical characteristics of SARS-CoV-2 Delta (B.1.617.2) and Omicron (B.1.1.529) infected patients from a single hospitalist service. BMC Infect Dis 23(1):747","journal-title":"BMC Infect Dis"},{"issue":"3","key":"12632_CR50","doi-asserted-by":"publisher","first-page":"428","DOI":"10.3390\/microorganisms12030428","volume":"12","author":"A Santos Coy-Arechavaleta","year":"2024","unstructured":"Santos Coy-Arechavaleta A, Alvarado-Yaah JE, Uribe-Noguez LA, Guerra-Castillo FX, Santacruz-Tinoco CE, Ram\u00f3n-Gallegos E et al (2024) Relationship between the Viral Load in Patients with Different COVID-19 Severities and SARS-CoV-2 Variants. Microorganisms 12(3):428","journal-title":"Microorganisms"},{"key":"12632_CR51","doi-asserted-by":"crossref","unstructured":"Al-Beltagi S, Goulding LV, Chang DKE, Mellits KH, Hayes CJ, Gershkovich P et al Emergent SARS-CoV-2 variants: comparative replication dynamics and high sensitivity to thapsigargin. Virulence 12(1):2946\u20132956","DOI":"10.1080\/21505594.2021.2006960"},{"issue":"1","key":"12632_CR52","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1038\/s12276-020-00552-0","volume":"53","author":"HJ Kim","year":"2021","unstructured":"Kim HJ, Kim IS, Lee SG, Kim YJ, Silwal P, Kim JY et al (2021) MiR-144-3p is associated with pathological inflammation in patients infected with Mycobacteroides abscessus. Exp Mol Med 53(1):136\u2013149","journal-title":"Exp Mol Med"},{"issue":"1","key":"12632_CR53","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1111\/crj.12194","volume":"10","author":"M Wang","year":"2016","unstructured":"Wang M, Huang Y, Liang Z, Liu D, Lu Y, Dai Y et al (2016) Plasma miRNAs might be promising biomarkers of chronic obstructive pulmonary disease. Clin Respir J 10(1):104\u2013111","journal-title":"Clin Respir J"},{"issue":"12","key":"12632_CR54","doi-asserted-by":"publisher","first-page":"a036996","DOI":"10.1101\/cshperspect.a036996","volume":"9","author":"H Taylor","year":"2019","unstructured":"Taylor H, Laurence ADJ, Uhlig HH (2019) The Role of PTEN in Innate and Adaptive Immunity. Cold Spring Harb Perspect Med 9(12):a036996","journal-title":"Cold Spring Harb Perspect Med"},{"issue":"3","key":"12632_CR55","doi-asserted-by":"publisher","first-page":"88","DOI":"10.3390\/genes8030088","volume":"8","author":"JNR Gnanaprakasam","year":"2017","unstructured":"Gnanaprakasam JNR, Wang R (2017) MYC in Regulating Immunity: Metabolism and Beyond. Genes 8(3):88","journal-title":"Genes"},{"key":"12632_CR56","doi-asserted-by":"publisher","first-page":"156750","DOI":"10.1016\/j.cyto.2024.156750","volume":"183","author":"X Wang","year":"2024","unstructured":"Wang X, Cao L, Liu S, Zhou Y, Zhou J, Zhao W et al (2024) The critical roles of IGFs in immune modulation and inflammation. Cytokine 183:156750","journal-title":"Cytokine"},{"key":"12632_CR57","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.cytogfr.2016.05.001","volume":"31","author":"EJ Hillmer","year":"2016","unstructured":"Hillmer EJ, Zhang H, Li HS, Watowich SS (2016) STAT3 signaling in immunity. Cytokine Growth Factor Rev 31:1\u201315","journal-title":"Cytokine Growth Factor Rev"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-026-12632-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11033-026-12632-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-026-12632-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T13:03:22Z","timestamp":1790082202000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11033-026-12632-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,29]]},"references-count":57,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["12632"],"URL":"https:\/\/doi.org\/10.1007\/s11033-026-12632-x","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,29]]},"assertion":[{"value":"28 May 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 August 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 August 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 September 2026","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Supplementary File 1 has been replaced with the correct file.","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Authors declare that they have no conflict of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the Regional Ethics Committee of the Jessenius Faculty of Medicine (code 65\/2021), and the research was performed in compliance with the Declaration of Helsinki. Informed consent was obtained from all participants.","order":2,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"1495"}}