{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T15:39:15Z","timestamp":1789486755466,"version":"build-2803163510"},"reference-count":59,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Special finance project of Pukou District of Nanjing city"},{"name":"Research and application of monitoring and control techniques for apple snail"},{"name":"Integrated demonstration and promotion project of key green control technologies for Pomacea spp. in rice fields","award":["JCTG [2025] 02-10"],"award-info":[{"award-number":["JCTG [2025] 02-10"]}]},{"name":"Project of collaborative promotion of major agricultural technologies","award":["2025-ZYXT-01"],"award-info":[{"award-number":["2025-ZYXT-01"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1007\/s11033-026-12753-3","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T13:17:07Z","timestamp":1789478227000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Structural and functional characterization of aquaporin 4 from the freshwater gastropod Pomacea canaliculata under temperature stress"],"prefix":"10.1007","volume":"53","author":[{"given":"Ran","family":"Wei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Xing","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Wen","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Dong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Fang","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-Xian","family":"Zha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4452-7125","authenticated-orcid":false,"given":"Yu-Zhou","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,15]]},"reference":[{"issue":"5491","key":"12753_CR1","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1126\/science.290.5491.481","volume":"290","author":"DX Fu","year":"2000","unstructured":"Fu DX, Libson A, Miercke LJW, Weitzman C, Nollert P, Krucinski J, Stroud RM (2000) Structure of a glycerol-conducting channel and the basis for its selectivity. Science 290(5491):481\u2013486. https:\/\/doi.org\/10.1126\/science.290.5491.481","journal-title":"Science"},{"key":"12753_CR2","doi-asserted-by":"publisher","unstructured":"Murata K, Mitsuoka K, Hirai T, Walz T, Agre P, Heymann JB, Engel A, Fujiyoshi Y (2000) Structural determinants of water permeation through aquaporin-1. Nature 407(2000):599\u2013605. https:\/\/doi.org\/10.1038\/35036519","DOI":"10.1038\/35036519"},{"issue":"4","key":"12753_CR3","doi-asserted-by":"publisher","first-page":"1198","DOI":"10.1073\/pnas.0707662104","volume":"105","author":"JS Hub","year":"2008","unstructured":"Hub JS, De Groot BL (2008) Mechanism of selectivity in aquaporins and aquaglyceroporins. Proc Natl Acad Sci USA 105(4):1198\u20131203. https:\/\/doi.org\/10.1073\/pnas.0707662104","journal-title":"Proc Natl Acad Sci USA"},{"issue":"10","key":"12753_CR4","doi-asserted-by":"publisher","first-page":"6731","DOI":"10.1073\/pnas.111152298","volume":"99","author":"MO Jensen","year":"2002","unstructured":"Jensen MO, Park S, Tajkhorshid E, Schulten K (2002) Energetics of glycerol conduction through aquaglyceroporin GlpF. Proc Natl Acad Sci USA 99(10):6731\u20136736. https:\/\/doi.org\/10.1073\/pnas.111152298","journal-title":"Proc Natl Acad Sci USA"},{"key":"12753_CR5","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1146\/annurev.physiol.70.113006.100452","volume":"70","author":"A Rojek","year":"2008","unstructured":"Rojek A, Praetorius J, Frokiaer J, Nielsen S, Fenton RA (2008) A current view of the mammalian aquaglyceroporins. Annu Rev Physiol 70:301\u2013327. https:\/\/doi.org\/10.1146\/annurev.physiol.70.113006.100452","journal-title":"Annu Rev Physiol"},{"issue":"5550","key":"12753_CR6","doi-asserted-by":"publisher","first-page":"2353","DOI":"10.1126\/science.1066115","volume":"294","author":"BL De Groot","year":"2001","unstructured":"De Groot BL, Grubmuller H (2001) Water permeation across biological membranes: mechanism and dynamics of aquaporin-1 and GlpF. Science 294(5550):2353\u20132357. https:\/\/doi.org\/10.1126\/science.1066115","journal-title":"Science"},{"issue":"9","key":"12753_CR7","doi-asserted-by":"publisher","first-page":"4135","DOI":"10.1073\/pnas.0910632107","volume":"107","author":"R Oliva","year":"2010","unstructured":"Oliva R, Calamita G, Thornton JM (2010) Pellegrini-Calace M Electrostatics of aquaporin and aquaglyceroporin channels correlates with their transport selectivity. Proc Natl Acad Sci USA 107(9):4135\u20134140. https:\/\/doi.org\/10.1073\/pnas.0910632107","journal-title":"Proc Natl Acad Sci USA"},{"issue":"4","key":"12753_CR8","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1017\/S0033583506004458","volume":"39","author":"T Gonen","year":"2006","unstructured":"Gonen T, Walz T (2006) The structure of aquaporins. Rev Biophys 39(4):361\u2013396. https:\/\/doi.org\/10.1017\/S0033583506004458","journal-title":"Rev Biophys"},{"issue":"17","key":"12753_CR9","doi-asserted-by":"publisher","first-page":"6305","DOI":"10.1073\/pnas.1321406111","volume":"111","author":"A Frick","year":"2014","unstructured":"Frick A, Eriksson UK, de Mattia F, Oberg F, Hedfalk K, Neutze R, de Grip WJ, Deen PMT, Tornroth-Horsefield S (2014) X-ray structure of human aquaporin 2 and its implications for nephrogenic diabetes insipidus and trafficking. Proc Natl Acad Sci USA 111(17):6305\u20136310. https:\/\/doi.org\/10.1073\/pnas.1321406111","journal-title":"Proc Natl Acad Sci USA"},{"issue":"12","key":"12753_CR10","doi-asserted-by":"publisher","first-page":"1974","DOI":"10.1096\/fj.04-3300com","volume":"20","author":"V Endeward","year":"2006","unstructured":"Endeward V, Musa-Aziz R, Cooper GJ et al (2006) Evidence that aquaporin 1 is a major pathway for CO2 transport across the human erythrocyte membrane. FASEB J 20(12):1974\u20131981. https:\/\/doi.org\/10.1096\/fj.04-3300com","journal-title":"FASEB J"},{"issue":"5055","key":"12753_CR11","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1126\/science.256.5055.385","volume":"256","author":"GM Preston","year":"1992","unstructured":"Preston GM, Carroll TP, Guggino WB, Agre P (1992) Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein. Science 256(5055):385\u2013387. https:\/\/doi.org\/10.1126\/science.256.5055.385","journal-title":"Science"},{"issue":"5","key":"12753_CR12","doi-asserted-by":"publisher","first-page":"1468","DOI":"10.1016\/j.bbagen.2013.12.001","volume":"1840","author":"F Abascal","year":"2014","unstructured":"Abascal F, Irisarri I, Zardoya R (2014) Diversity and evolution of membrane intrinsic proteins. Biochim Biophys Acta 1840(5):1468\u20131481. https:\/\/doi.org\/10.1016\/j.bbagen.2013.12.001","journal-title":"Biochim Biophys Acta"},{"issue":"1","key":"12753_CR13","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1086\/BBLv229n1p6","volume":"229","author":"RN Finn","year":"2015","unstructured":"Finn RN, Cerda J (2015) Evolution and functional diversity of aquaporins. Biol Bull 229(1):6\u201323. https:\/\/doi.org\/10.1086\/BBLv229n1p6","journal-title":"Biol Bull"},{"issue":"5","key":"12753_CR14","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1007\/s00109-008-0303-9","volume":"86","author":"AS Verkman","year":"2008","unstructured":"Verkman AS, Hara-Chikuma M, Papadopoulos MC (2008) Papadopoulos, Aquaporins - new players in cancer biology. J Mol Med 86(5):523\u2013529. https:\/\/doi.org\/10.1007\/s00109-008-0303-9","journal-title":"J Mol Med"},{"issue":"10","key":"12753_CR15","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1002\/jez.634","volume":"313A","author":"J Cerda","year":"2010","unstructured":"Cerda J, Finn RN (2010) Piscine aquaporins: an overview of recent advances. J Exp Zool A 313A(10):623\u2013650. https:\/\/doi.org\/10.1002\/jez.634","journal-title":"J Exp Zool A"},{"issue":"3","key":"12753_CR16","doi-asserted-by":"publisher","first-page":"e58563","DOI":"10.1371\/journal.pone.0058563","volume":"8","author":"J Meng","year":"2013","unstructured":"Meng J, Zhu QH, Zhang LL, Li C, Li L, She Z, Huang B, Zhang G (2013) Genome and transcriptome analyses provide insight into the euryhaline adaptation mechanism of Crassostrea gigas. PLoS ONE 8(3):e58563. https:\/\/doi.org\/10.1371\/journal.pone.0058563","journal-title":"PLoS ONE"},{"issue":"3","key":"12753_CR17","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1007\/s00232-014-9629-0","volume":"247","author":"JR Pienkowska","year":"2014","unstructured":"Pienkowska JR, Kosicka E, Wojtkowska M, Kmita H, Lesicki A (2014) Molecular Identification of first putative aquaporins in snails. J Membrane Biol 247(3):239\u2013252. https:\/\/doi.org\/10.1007\/s00232-014-9629-0","journal-title":"J Membrane Biol"},{"issue":"3","key":"12753_CR18","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1093\/icb\/36.3.364","volume":"36","author":"TH Dietz","year":"1996","unstructured":"Dietz TH, Wilcox SJ, Byrne R, Lynn JW, Silverman H (1996) Osmotic and ionic regulation of North American Zebra Mussels (Dreissena polymorpha). Am Zool 36(3):364\u2013372. https:\/\/doi.org\/10.1093\/icb\/36.3.364","journal-title":"Am Zool"},{"key":"12753_CR19","doi-asserted-by":"publisher","first-page":"107392","DOI":"10.1016\/j.ympev.2022.107392","volume":"168","author":"YL Jia","year":"2022","unstructured":"Jia YL, Xu F, Liu X (2022) Duplication and subsequent functional diversification of aquaporin family in Pacific abalone Haliotis discus hannai. Mol Phylogenet Evol 168:107392. https:\/\/doi.org\/10.1016\/j.ympev.2022.107392","journal-title":"Mol Phylogenet Evol"},{"issue":"1","key":"12753_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12864-022-08445-4","volume":"23","author":"YL Jia","year":"2022","unstructured":"Jia YL, Liu X (2022) Diversification of the aquaporin family in geographical isolated oyster species promote the adaptability to dynamic environments. BMC Genomics 23(1):1\u201320. https:\/\/doi.org\/10.1186\/s12864-022-08445-4","journal-title":"BMC Genomics"},{"key":"12753_CR21","doi-asserted-by":"crossref","unstructured":"Cowie RH (2002) Apple snails (Ampullariidae) as agricultural pests: their biology, impacts and management. CABI Publishing 145\u2013192","DOI":"10.1079\/9780851993201.0145"},{"issue":"4","key":"12753_CR22","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1111\/j.1472-4642.2008.00483.x","volume":"14","author":"KA Hayes","year":"2010","unstructured":"Hayes KA, Joshi RC, Thiengo SC, Cowie RH (2010) Out of South America: Multiple origins of non-native apple snails in Asia. Divers Distrib 14(4):701\u2013712. https:\/\/doi.org\/10.1111\/j.1472-4642.2008.00483.x","journal-title":"Divers Distrib"},{"issue":"1","key":"12753_CR23","doi-asserted-by":"publisher","first-page":"e12045","DOI":"10.1038\/s41598-024-62554-6","volume":"14","author":"R Wei","year":"2024","unstructured":"Wei R, Chang YW, Xie HF, Wu CD, Yuan DR, Du YZ (2024) Population genetic structure of Pomacea canaliculata in China based on the COI and ITS1 genes. Sci Rep 14(1):e12045. https:\/\/doi.org\/10.1038\/s41598-024-62554-6","journal-title":"Sci Rep"},{"key":"12753_CR24","doi-asserted-by":"publisher","first-page":"56","DOI":"10.6620\/ZS.2025.64-56","volume":"64","author":"R Wei","year":"2025","unstructured":"Wei R, Xie HF, Wu CD, Hu J, Du YZ (2025) Impacts of climate change on the potential habitat suitability of the apple snails Pomacea canaliculata and Pomacea maculata in East Asia. Zool Stud 64:56. https:\/\/doi.org\/10.6620\/ZS.2025.64-56","journal-title":"Zool Stud"},{"issue":"16","key":"12753_CR25","doi-asserted-by":"publisher","first-page":"2558","DOI":"10.1242\/jeb.031500","volume":"212","author":"K Matsukura","year":"2009","unstructured":"Matsukura K, Tsumuki H, Izumi Y, Wada T (2009) Physiological response to low temperature in the freshwater apple snail, Pomacea canaliculata (Gastropoda: Ampullariidae). J Exp Biol 212(16):2558\u20132563. https:\/\/doi.org\/10.1242\/jeb.031500","journal-title":"J Exp Biol"},{"issue":"11","key":"12753_CR26","doi-asserted-by":"publisher","first-page":"1899","DOI":"10.1007\/s00484-017-1376-3","volume":"61","author":"G Gilioli","year":"2017","unstructured":"Gilioli G, Pasquali S, Martin PR, Carlsson N, Mariani LA (2017) A temperature-dependent physiologically based model for the invasive apple snail Pomacea canaliculata. Int J Biometeorol 61(11):1899\u20131911. https:\/\/doi.org\/10.1007\/s00484-017-1376-3","journal-title":"Int J Biometeorol"},{"key":"12753_CR27","doi-asserted-by":"publisher","first-page":"146276","DOI":"10.1016\/j.ijbiomac.2025.146276","volume":"321","author":"R Wei","year":"2025","unstructured":"Wei R, Tong YH, Lu MX, Hu J, Xie HF, Wu CD (2025) Functional and structural characterization of an aquaporin 5 from Pomacea canaliculata. Int J Biol Macromol 321:146276. https:\/\/doi.org\/10.1016\/j.ijbiomac.2025.146276","journal-title":"Int J Biol Macromol"},{"issue":"W1","key":"12753_CR28","doi-asserted-by":"publisher","first-page":"W408","DOI":"10.1093\/nar\/gkv451","volume":"43","author":"L Dobson","year":"2015","unstructured":"Dobson L, Rem\u00e9nyi I, Tusn\u00e1dy GE (2015) CCTOP: a Consensus Constrained TOPology prediction web server. Nucleic Acids Res 43(W1):W408\u2013W412. https:\/\/doi.org\/10.1093\/nar\/gkv451","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"12753_CR29","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1093\/nar\/gky427","volume":"46","author":"W Andrew","year":"2018","unstructured":"Andrew W, Martino B, Stefan B, Gabriel S, Gerardo T, Rafal G, Heer FT, Beer TAPD, Christine R, Lorenza B (2018) SWISS-MODEL: homology modelling of protein structures and complexes. Nucl Acid Res 46(1):296\u2013303. https:\/\/doi.org\/10.1093\/nar\/gky427","journal-title":"Nucl Acid Res"},{"key":"12753_CR30","doi-asserted-by":"publisher","first-page":"57","DOI":"10.3389\/fphys.2018.00057","volume":"9","author":"MX Lu","year":"2018","unstructured":"Lu MX, Pan DD, Xu J, Liu Y, Wang GR, Du YZ (2018) Identification and functional analysis of the first aquaporin from striped stem borer, Chilo suppressalis. Front Physiol 9:57. https:\/\/doi.org\/10.3389\/fphys.2018.00057","journal-title":"Front Physiol"},{"key":"12753_CR31","first-page":"1014","volume":"40","author":"C Zhou","year":"2017","unstructured":"Zhou C, Han ZJ (2017) Aquaporin gene cloning and its possible contribution to insecticide metabolism in Laodelphax striatellus. J Nanjing Agricultural Univ 40:1014\u20131022","journal-title":"J Nanjing Agricultural Univ"},{"issue":"26","key":"12753_CR32","doi-asserted-by":"publisher","first-page":"16140","DOI":"10.1074\/jbc.272.26.16140","volume":"272","author":"B Yang","year":"1997","unstructured":"Yang B, Verkman AS (1997) Water and glycerol permeabilities of aquaporins 1\u20135 and MIP determined quantitatively by expression of epitope-tagged constructs in Xenopus oocytes. J Biol Chem 272(26):16140\u201316146","journal-title":"J Biol Chem"},{"issue":"1","key":"12753_CR33","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1152\/ajpcell.1991.260.1.C26","volume":"260","author":"D Zhang","year":"1991","unstructured":"Zhang D, Verkman AS (1991) Water and urea permeability properties of Xenopus oocytes: expression of mRNA from toad urinary bladder. Am J Physiol 260(1):26\u201334. https:\/\/doi.org\/10.1152\/ajpcell.1991.260.1.C26","journal-title":"Am J Physiol"},{"key":"12753_CR34","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.sbi.2015.08.004","volume":"33","author":"S Kreida","year":"2015","unstructured":"Kreida S, T\u00f6rnroth-Horsefield S (2015) Structural insights into aquaporin selectivity and regulation. Curr Opin Struct Biol 33:126\u2013134. https:\/\/doi.org\/10.1016\/j.sbi.2015.08.004","journal-title":"Curr Opin Struct Biol"},{"key":"12753_CR35","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/978-3-540-79885-9_1","volume":"190","author":"JM Carbrey","year":"2009","unstructured":"Carbrey JM, Agre P (2009) Discovery of the aquaporins and development of the field. Handb Exp Pharmacol 190:3\u201328. https:\/\/doi.org\/10.1007\/978-3-540-79885-9_1","journal-title":"Handb Exp Pharmacol"},{"issue":"6","key":"12753_CR36","doi-asserted-by":"publisher","first-page":"1577","DOI":"10.3390\/ijms19061577","volume":"19","author":"L Calvanese","year":"2018","unstructured":"Calvanese L, D\u2019Auria G, Vangone A, Falcigno L, Oliva R (2018) Structural Basis for Mutations of Human Aquaporins Associated to Genetic Diseases. Int J Mol Sci 19(6):1577. https:\/\/doi.org\/10.3390\/ijms19061577","journal-title":"Int J Mol Sci"},{"issue":"1","key":"12753_CR37","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1124\/jpet.109.154245","volume":"331","author":"N Gonzalez","year":"2009","unstructured":"Gonzalez N, Nakagawa T, Mantey SA, Sancho V, Uehara H, Katsuno T, Jensen RT (2009) Molecular basis for the selectivity of the mammalian bombesin peptide, neuromedin B, for its receptor. J Pharmacol Exp Ther 331(1):265\u2013276. https:\/\/doi.org\/10.1124\/jpet.109.154245","journal-title":"J Pharmacol Exp Ther"},{"issue":"5","key":"12753_CR38","doi-asserted-by":"publisher","first-page":"107219","DOI":"10.1016\/j.jbc.2024.107219","volume":"300","author":"C Liu","year":"2024","unstructured":"Liu C, Chen IS, Tateyama M, Kubo Y (2024) Structural determinants of the direct inhibition of GIRK channels by Sigma-1 receptor antagonist. J Biol Chem 300(5):107219. https:\/\/doi.org\/10.1016\/j.jbc.2024.107219","journal-title":"J Biol Chem"},{"issue":"2","key":"12753_CR39","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1073\/pnas.0507225103","volume":"103","author":"E Beitz","year":"2006","unstructured":"Beitz E, Wu B, Holm LM, Schultz JE, Zeuthen T (2006) Point mutations in the aromatic\/arginine region in aquaporin 1 allow passage of urea, glycerol, ammonia, and protons. Proc Natl Acad Sci USA 103(2):269\u2013274. https:\/\/doi.org\/10.1073\/pnas.0507225103","journal-title":"Proc Natl Acad Sci USA"},{"issue":"2","key":"12753_CR40","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1080\/13235818.2020.1716442","volume":"40","author":"E Kosicka","year":"2020","unstructured":"Kosicka E, Lesicki A, Pienkowska JR (2020) Molluscan aquaporins: an overview, with some notes on their role in the entry into aestivation in gastropods. Molluscan Res 40(2):101\u2013111. https:\/\/doi.org\/10.1080\/13235818.2020.1716442","journal-title":"Molluscan Res"},{"issue":"8","key":"12753_CR41","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1016\/j.bbamem.2006.02.024","volume":"1758","author":"K Ishibashi","year":"2006","unstructured":"Ishibashi K (2006) Aquaporin subfamily with unusual NPA boxes. Biochim Biophys Acta 1758(8):989\u2013993. https:\/\/doi.org\/10.1016\/j.bbamem.2006.02.024","journal-title":"Biochim Biophys Acta"},{"issue":"6","key":"12753_CR42","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1038\/nsmb.1431","volume":"15","author":"ZE Newby","year":"2008","unstructured":"Newby ZE, O\u2019Connell JIII, Robles-Colmenares Y, Khademi S, Miercke LJ, Stroud RM (2008) Crystal structure of the aquaglyceroporin PfAQP from the malarial parasite Plasmodium falciparum. Nat Struct Mol Biol 15(6):619\u2013625. https:\/\/doi.org\/10.1038\/nsmb.1431","journal-title":"Nat Struct Mol Biol"},{"issue":"36","key":"12753_CR43","doi-asserted-by":"publisher","first-page":"19184","DOI":"10.1074\/jbc.M116.740217","volume":"291","author":"M Assentoft","year":"2016","unstructured":"Assentoft M, Kaptan S, Schneider HP, Deitmer JW, de Groot BL, MacAulay N (2016) Aquaporin 4 as a NH3 Channel. J Biol Chem 291(36):19184\u201319195. https:\/\/doi.org\/10.1074\/jbc.M116.740217","journal-title":"J Biol Chem"},{"key":"12753_CR44","doi-asserted-by":"publisher","first-page":"S7","DOI":"10.1186\/1471-2164-10-S2-S7","volume":"10","author":"RD Isokpehi","year":"2009","unstructured":"Isokpehi RD, Rajnarayanan RV, Jeffries CD, Oyeleye TO, Cohly HH (2009) Integrative sequence and tissue expression profiling of chicken and mammalian aquaporins. BMC Genomics 10:S7. https:\/\/doi.org\/10.1186\/1471-2164-10-S2-S7","journal-title":"BMC Genomics"},{"key":"12753_CR45","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1186\/1471-2164-15-173","volume":"15","author":"KV Khabudaev","year":"2014","unstructured":"Khabudaev KV, Petrova DP, Grachev MA, Likhoshway YV (2014) A new subfamily LIP of the major intrinsic proteins. BMC Genomics 15:173. https:\/\/doi.org\/10.1186\/1471-2164-15-173","journal-title":"BMC Genomics"},{"issue":"1","key":"12753_CR46","doi-asserted-by":"publisher","first-page":"9180","DOI":"10.1038\/s41598-022-13195-0","volume":"12","author":"YX Zhang","year":"2022","unstructured":"Zhang YX, Fei SH, Xu YM, He Y, Zhu ZJ, Liu YY (2022) The structure, function and expression analysis of the nodulin 26-like intrinsic protein subfamily of plant aquaporins in tomato. Sci Rep 12(1):9180. https:\/\/doi.org\/10.1038\/s41598-022-13195-0","journal-title":"Sci Rep"},{"issue":"18","key":"12753_CR47","doi-asserted-by":"publisher","first-page":"7437","DOI":"10.1073\/pnas.0902725106","volume":"106","author":"J Ho","year":"2009","unstructured":"Ho J, Yeh R, Chorny I et al (2009) Crystal structure of human aquaporin 4 at 1.8 \u00c5 and its mechanism of conductance. PNAS 106(18):7437\u20137442. https:\/\/doi.org\/10.1073\/pnas.0902725106","journal-title":"PNAS"},{"issue":"12","key":"12753_CR48","doi-asserted-by":"publisher","first-page":"2410","DOI":"10.1016\/j.bbagen.2015.08.023","volume":"1848","author":"P Kitchen","year":"2015","unstructured":"Kitchen P, Day RE, Salman MM, Conner MT, Bill RM, Conner AC (2015) Beyond water homeostasis: diverse functional roles of mammalian aquaporins. BBA-Gen Subj 1848(12):2410\u20132421. https:\/\/doi.org\/10.1016\/j.bbagen.2015.08.023","journal-title":"BBA-Gen Subj"},{"key":"12753_CR49","doi-asserted-by":"publisher","first-page":"115","DOI":"10.4137\/BBI.S7316","volume":"5","author":"SS Simmons","year":"2011","unstructured":"Simmons SS, Isokpehi RD, Brown SD et al (2011) Functional Annotation Analytics of Rhodopseudomonas palustris Genomes. Bioinform Biol Insights 5:115\u2013129. https:\/\/doi.org\/10.4137\/BBI.S7316","journal-title":"Bioinform Biol Insights"},{"issue":"6866","key":"12753_CR50","doi-asserted-by":"publisher","first-page":"872","DOI":"10.1038\/414872a","volume":"414","author":"HX Sui","year":"2001","unstructured":"Sui HX, Han BG, Lee JK, Walian P, Jap BK (2001) Structural basis of water-specific transport through the AQP1 water channel. Nature 414(6866):872\u2013878. https:\/\/doi.org\/10.1038\/414872a","journal-title":"Nature"},{"issue":"2","key":"12753_CR51","doi-asserted-by":"publisher","first-page":"69","DOI":"10.3390\/fishes7020069","volume":"7","author":"WB Ruan","year":"2022","unstructured":"Ruan WB, Dong YH, Lin ZH, He L (2022) Molecular characterization of aquaporin genes from the razor clam Sinonovacula constricta and their potential role in salinity tolerance. Fishes 7(2):69. https:\/\/doi.org\/10.3390\/fishes7020069","journal-title":"Fishes"},{"issue":"7077","key":"12753_CR52","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1038\/nature04316","volume":"439","author":"S Tornroth-Horsefield","year":"2006","unstructured":"Tornroth-Horsefield S, Wang Y, Hedfalk K, Johanson U, Karlsson M, Tajkhorshid E, Neutze R, Kjellbam P (2006) Structural mechanism of plant aquaporin gating. Nature 439(7077):688\u2013694. https:\/\/doi.org\/10.1038\/nature04316","journal-title":"Nature"},{"issue":"19","key":"12753_CR53","doi-asserted-by":"publisher","first-page":"3161","DOI":"10.1007\/s00018-009-0075-6","volume":"66","author":"U Ludewig","year":"2009","unstructured":"Ludewig U, Dynowski M (2009) Plant aquaporin selectivity: where transport assays, computer simulations and physiology meet. Cell Mol Life Sci 66(19):3161\u20133175. https:\/\/doi.org\/10.1007\/s00018-009-0075-6","journal-title":"Cell Mol Life Sci"},{"key":"12753_CR54","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1146\/annurev.arplant.59.032607.092734","volume":"59","author":"C Maurel","year":"2008","unstructured":"Maurel C, Verdoucq L, Luu DT, Santoni V (2008) Plant aquaporins: membrane channels with multiple integrated functions. Annu Rev Plant Biol 59:595\u2013624. https:\/\/doi.org\/10.1146\/annurev.arplant.59.032607.092734","journal-title":"Annu Rev Plant Biol"},{"issue":"1","key":"12753_CR55","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1186\/s12915-025-02262-3","volume":"23","author":"\u00c1 Rey-Alfonso","year":"2025","unstructured":"Rey-Alfonso \u00c1, Maestro JL, Chauvign\u00e9 F, G\u00f3mez-Garrido J, Alioto T, Bossier P, Finn RN, Cerd\u00e0 J (2025) Co-opted and canonical glycerol channels play a major role during anhydrobiosis of an extremophile crustacean. BMC Biol 23(1):151. https:\/\/doi.org\/10.1186\/s12915-025-02262-3","journal-title":"BMC Biol"},{"key":"12753_CR56","doi-asserted-by":"publisher","unstructured":"Cossins AR, Bowler K (1987) Temperature Biology of Animals. Springer Netherlands. https:\/\/doi.org\/10.1007\/978-94-009-3127-5","DOI":"10.1007\/978-94-009-3127-5"},{"issue":"Pt 2","key":"12753_CR57","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1242\/JEB.203.2.405","volume":"203","author":"PH Donohoe","year":"2000","unstructured":"Donohoe PH, West TG, Boutilier RG (2000) Factors affecting membrane permeability and ionic homeostasis in the cold-submerged frog. J Exp Biol 203(Pt 2):405. https:\/\/doi.org\/10.1242\/JEB.203.2.405","journal-title":"J Exp Biol"},{"key":"12753_CR58","doi-asserted-by":"publisher","first-page":"6725728","DOI":"10.1155\/2018\/6725728","volume":"2018","author":"NY Li","year":"2018","unstructured":"Li NY, Qiu ZC, Lu XM, Shi BC, Sun XD, Tang XZ, Qiao XG (2018) Comparative Transcriptome Analysis of Temperature-Induced Green Discoloration in Garlic. Int J Genomics 2018:6725728. https:\/\/doi.org\/10.1155\/2018\/6725728","journal-title":"Int J Genomics"},{"issue":"24","key":"12753_CR59","doi-asserted-by":"publisher","first-page":"15552","DOI":"10.3390\/ijms232415552","volume":"23","author":"F Habibpourmehraban","year":"2022","unstructured":"Habibpourmehraban F, Atwell BJ, Haynes PA (2022) Unique and Shared Proteome Responses of Rice Plants (Oryza sativa) to Individual Abiotic Stresses. Int J Mol Sci 23(24):15552. https:\/\/doi.org\/10.3390\/ijms232415552","journal-title":"Int J Mol Sci"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-026-12753-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11033-026-12753-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-026-12753-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T13:17:11Z","timestamp":1789478231000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11033-026-12753-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,15]]},"references-count":59,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["12753"],"URL":"https:\/\/doi.org\/10.1007\/s11033-026-12753-3","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,15]]},"assertion":[{"value":"19 May 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that they have no conflict of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"1579"}}