{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T10:45:37Z","timestamp":1792233937337,"version":"4.4.0"},"reference-count":92,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T00:00:00Z","timestamp":1792195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T00:00:00Z","timestamp":1792195200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100007449","name":"Takeda Science Foundation","doi-asserted-by":"publisher","award":["FY2020"],"award-info":[{"award-number":["FY2020"]}],"id":[{"id":"10.13039\/100007449","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Biol Rep"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1007\/s11033-026-12912-6","type":"journal-article","created":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T10:09:45Z","timestamp":1792231785000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Adhesion gateway: decoding mechanobiological cues for cytoskeletal reconfiguration"],"prefix":"10.1007","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8077-584X","authenticated-orcid":false,"given":"Gangotry","family":"Mukhopadhyay","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1574-5158","authenticated-orcid":false,"given":"Karthick","family":"Velu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2514-6658","authenticated-orcid":false,"given":"Inbakandan","family":"Dhinakarasamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3615-8200","authenticated-orcid":false,"given":"Prathap","family":"Somu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7684-1311","authenticated-orcid":false,"given":"J.","family":"Iyyappan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1320-9503","authenticated-orcid":false,"given":"Ravi","family":"Mani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,17]]},"reference":[{"key":"12912_CR1","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1038\/s41580-022-00531-5","volume":"24","author":"P Kanchanawong","year":"2023","unstructured":"Kanchanawong P, Calderwood DA (2023) Organization, dynamics and mechanoregulation of integrin-mediated cell\u2013ECM adhesions. Nat Rev Mol Cell Biol 24:142\u2013161. https:\/\/doi.org\/10.1038\/s41580-022-00531-5","journal-title":"Nat Rev Mol Cell Biol"},{"key":"12912_CR2","doi-asserted-by":"publisher","first-page":"121659","DOI":"10.1016\/j.biomaterials.2022.121659","volume":"287","author":"N Xiang","year":"2022","unstructured":"Xiang N, Yao Y, Yuen JSK et al (2022) Edible films for cultivated meat production. Biomaterials 287:121659. https:\/\/doi.org\/10.1016\/j.biomaterials.2022.121659","journal-title":"Biomaterials"},{"key":"12912_CR3","doi-asserted-by":"publisher","unstructured":"Zhang Q, Zhang M, Meng N et al (2023) Mechanobiology of the articular chondrocyte. Bone Cell Biomechanics, Mechanobiology and Bone Diseases, Elsevier Inc., pp 249\u2013287 https:\/\/doi.org\/10.1016\/B978-0-323-96123-3.00016-6","DOI":"10.1016\/B978-0-323-96123-3.00016-6"},{"key":"12912_CR4","doi-asserted-by":"publisher","unstructured":"Sumigray KD, Lechler T (2015) Cell Adhesion in Epidermal Development and Barrier Formation. Current Topics in Developmental Biology, 1st edn. Elsevier Inc., pp 383\u2013414. DOI: https:\/\/doi.org\/10.1016\/bs.ctdb.2014.11.027","DOI":"10.1016\/bs.ctdb.2014.11.027"},{"key":"12912_CR5","doi-asserted-by":"publisher","first-page":"1189","DOI":"10.3390\/biology10111189","volume":"10","author":"K Legerstee","year":"2021","unstructured":"Legerstee K, Houtsmuller A (2021) A Layered View on Focal Adhesions. Biology (Basel) 10:1189. https:\/\/doi.org\/10.3390\/biology10111189","journal-title":"Biology (Basel)"},{"key":"12912_CR6","doi-asserted-by":"publisher","first-page":"173","DOI":"10.3390\/biom15020173","volume":"15","author":"Z Li","year":"2025","unstructured":"Li Z, Shao R, Xin H et al (2025) Paxillin and Kindlin: Research Progress and Biological Functions. Biomolecules 15:173. https:\/\/doi.org\/10.3390\/biom15020173","journal-title":"Biomolecules"},{"key":"12912_CR7","doi-asserted-by":"publisher","first-page":"213277","DOI":"10.1016\/j.bioadv.2022.213277","volume":"145","author":"C Grandy","year":"2023","unstructured":"Grandy C, Port F, Pfeil J et al (2023) Cell shape and tension alter focal adhesion structure. Biomaterials Adv 145:213277. https:\/\/doi.org\/10.1016\/j.bioadv.2022.213277","journal-title":"Biomaterials Adv"},{"key":"12912_CR8","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1186\/s11671-024-04052-2","volume":"19","author":"P Elblov\u00e1","year":"2024","unstructured":"Elblov\u00e1 P, Lunova M, Dejneka A et al (2024) Impact of mechanical cues on key cell functions and cell-nanoparticle interactions. Discover Nano 19:106. https:\/\/doi.org\/10.1186\/s11671-024-04052-2","journal-title":"Discover Nano"},{"key":"12912_CR9","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1039\/c6bm00100a","volume":"4","author":"M Kamimura","year":"2016","unstructured":"Kamimura M, Sugawara M, Yamamoto S et al (2016) Dynamic control of cell adhesion on a stiffness-tunable substrate for analyzing the mechanobiology of collective cell migration. Biomater Sci 4:933\u2013937. https:\/\/doi.org\/10.1039\/c6bm00100a","journal-title":"Biomater Sci"},{"key":"12912_CR10","doi-asserted-by":"publisher","first-page":"19","DOI":"10.4161\/cam.4.1.9569","volume":"4","author":"F Boccafoschi","year":"2010","unstructured":"Boccafoschi F, Bosetti M, Sandra PM et al (2010) Effects of mechanical stress on cell adhesion. Cell Adh Migr 4:19\u201325. https:\/\/doi.org\/10.4161\/cam.4.1.9569","journal-title":"Cell Adh Migr"},{"key":"12912_CR11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1091\/mbc.E23-03-0101","volume":"35","author":"SE Greer","year":"2024","unstructured":"Greer SE, Haller SJ, Lee D, Dudley AT (2024) N-cadherin and \u03b21 integrin coordinately regulate growth plate cartilage architecture. Mol Biol Cell 35:1\u201314. https:\/\/doi.org\/10.1091\/mbc.E23-03-0101","journal-title":"Mol Biol Cell"},{"key":"12912_CR12","doi-asserted-by":"publisher","first-page":"3638","DOI":"10.1021\/acsabm.3c00126","volume":"6","author":"N Malandain","year":"2023","unstructured":"Malandain N, Sanz-Fraile H, Farr\u00e9 R et al (2023) Cell-Laden 3D Hydrogels of Type I Collagen Incorporating Bacterial Nanocellulose Fibers. ACS Appl Bio Mater 6:3638\u20133647. https:\/\/doi.org\/10.1021\/acsabm.3c00126","journal-title":"ACS Appl Bio Mater"},{"key":"12912_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pone.0260593","volume":"16","author":"DMK Aladin","year":"2021","unstructured":"Aladin DMK, Chu YS, Shen S et al (2021) Extracellular domains of E-cadherin determine key mechanical phenotypes of an epithelium through cell- And non-cellautonomous outside-in signaling. PLoS ONE 16:1\u201322. https:\/\/doi.org\/10.1371\/journal.pone.0260593","journal-title":"PLoS ONE"},{"key":"12912_CR14","doi-asserted-by":"publisher","first-page":"100067","DOI":"10.1016\/j.mbm.2024.100067","volume":"2","author":"Z Xu","year":"2024","unstructured":"Xu Z, Xu F, Cheng B (2024) The motor-clutch model in mechanobiology and mechanomedicine. Mechanobiol Med 2:100067. https:\/\/doi.org\/10.1016\/j.mbm.2024.100067","journal-title":"Mechanobiol Med"},{"key":"12912_CR15","doi-asserted-by":"publisher","first-page":"6795","DOI":"10.1039\/d1bm01061a","volume":"9","author":"IL Chin","year":"2021","unstructured":"Chin IL, Hool L, Choi YS (2021) Interrogating cardiac muscle cell mechanobiology on stiffness gradient hydrogels. Biomater Sci 9:6795\u20136806. https:\/\/doi.org\/10.1039\/d1bm01061a","journal-title":"Biomater Sci"},{"key":"12912_CR16","doi-asserted-by":"publisher","first-page":"43403","DOI":"10.1021\/acsami.3c07785","volume":"15","author":"M Liboz","year":"2023","unstructured":"Liboz M, Allard A, Malo M et al (2023) Using Adhesive Micropatterns and AFM to Assess Cancer Cell Morphology and Mechanics. ACS Appl Mater Interfaces 15:43403\u201343413. https:\/\/doi.org\/10.1021\/acsami.3c07785","journal-title":"ACS Appl Mater Interfaces"},{"key":"12912_CR17","doi-asserted-by":"publisher","first-page":"4885","DOI":"10.1021\/acsabm.1c00189","volume":"4","author":"F Ejeian","year":"2021","unstructured":"Ejeian F, Haghani E, Nasr-Esfahani MH et al (2021) Mechanobiology of Dental Pulp Stem Cells at the Interface of Aqueous-Based Fabricated ZIF8 Thin Film. ACS Appl Bio Mater 4:4885\u20134895. https:\/\/doi.org\/10.1021\/acsabm.1c00189","journal-title":"ACS Appl Bio Mater"},{"key":"12912_CR18","doi-asserted-by":"publisher","first-page":"19913","DOI":"10.1021\/acsomega.2c01703","volume":"7","author":"X Zhang","year":"2022","unstructured":"Zhang X, Zhang T, Liu B et al (2022) Effects of Biomimetic Micropatterned Surfaces on the Adhesion and Morphology of Cervical Cancer Cells. ACS Omega 7:19913\u201319919. https:\/\/doi.org\/10.1021\/acsomega.2c01703","journal-title":"ACS Omega"},{"key":"12912_CR19","doi-asserted-by":"publisher","first-page":"2416","DOI":"10.1002\/jbm.a.36100","volume":"105","author":"CR Anderson","year":"2017","unstructured":"Anderson CR, Gambinossi F, DiLillo KM et al (2017) Tuning reversible cell adhesion to methacrylate-based thermoresponsive polymers: Effects of composition on substrate hydrophobicity and cellular responses. J Biomed Mater Res A 105:2416\u20132428. https:\/\/doi.org\/10.1002\/jbm.a.36100","journal-title":"J Biomed Mater Res A"},{"key":"12912_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1126\/sciadv.aax0317","volume":"6","author":"SJ Tan","year":"2020","unstructured":"Tan SJ, Chang AC, Anderson SM et al (2020) Regulation and dynamics of force transmission at individual cell-matrix adhesion bonds. Sci Adv 6:1\u201311. https:\/\/doi.org\/10.1126\/sciadv.aax0317","journal-title":"Sci Adv"},{"key":"12912_CR21","doi-asserted-by":"publisher","first-page":"e26182","DOI":"10.1371\/journal.pone.0026182","volume":"6","author":"AM Pereira","year":"2011","unstructured":"Pereira AM, Tudor C, Kanger JS et al (2011) Integrin-Dependent Activation of the JNK Signaling Pathway by Mechanical Stress. PLoS ONE 6:e26182. https:\/\/doi.org\/10.1371\/journal.pone.0026182","journal-title":"PLoS ONE"},{"key":"12912_CR22","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.pbiomolbio.2022.08.005","volume":"176","author":"ER Kahle","year":"2022","unstructured":"Kahle ER, Patel N, Sreenivasappa HB et al (2022) Targeting cell-matrix interface mechanobiology by integrating AFM with fluorescence microscopy. Prog Biophys Mol Biol 176:67\u201381. https:\/\/doi.org\/10.1016\/j.pbiomolbio.2022.08.005","journal-title":"Prog Biophys Mol Biol"},{"key":"12912_CR23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41467-021-22985-5","volume":"12","author":"ED Tabdanov","year":"2021","unstructured":"Tabdanov ED, Rodr\u00edguez-Merced NJ, Cartagena-Rivera AX et al (2021) Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments. Nat Commun 12:1\u201317. https:\/\/doi.org\/10.1038\/s41467-021-22985-5","journal-title":"Nat Commun"},{"key":"12912_CR24","doi-asserted-by":"publisher","first-page":"eabe9446","DOI":"10.1126\/SCIADV.ABE9446","volume":"7","author":"MJ Mondrinos","year":"2021","unstructured":"Mondrinos MJ, Alisafaei F, Yi AY et al (2021) Surface-directed engineering of tissue anisotropy in microphysiological models of musculoskeletal tissue. Sci Adv 7:eabe9446. https:\/\/doi.org\/10.1126\/SCIADV.ABE9446","journal-title":"Sci Adv"},{"key":"12912_CR25","doi-asserted-by":"publisher","first-page":"2652","DOI":"10.1016\/j.cell.2024.04.006","volume":"187","author":"CM Nelson","year":"2024","unstructured":"Nelson CM, Xiao B, Wickstr\u00f6m SA et al (2024) Mechanobiology: Shaping the future of cellular form and function. Cell 187:2652\u20132656. https:\/\/doi.org\/10.1016\/j.cell.2024.04.006","journal-title":"Cell"},{"key":"12912_CR26","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1038\/s41592-024-02277-8","volume":"21","author":"I L\u00fcchtefeld","year":"2024","unstructured":"L\u00fcchtefeld I, Pivkin IV, Gardini L et al (2024) Dissecting cell membrane tension dynamics and its effect on Piezo1-mediated cellular mechanosensitivity using force-controlled nanopipettes. Nat Methods 21:1063\u20131073. https:\/\/doi.org\/10.1038\/s41592-024-02277-8","journal-title":"Nat Methods"},{"key":"12912_CR27","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1021\/acs.langmuir.3c03046","volume":"40","author":"X Yang","year":"2024","unstructured":"Yang X, Yang Y, Zhang Z, Li M (2024) Deep Learning Image Recognition-Assisted Atomic Force Microscopy for Single-Cell Efficient Mechanics in Co-culture Environments. Langmuir 40:837\u2013852. https:\/\/doi.org\/10.1021\/acs.langmuir.3c03046","journal-title":"Langmuir"},{"key":"12912_CR28","doi-asserted-by":"publisher","first-page":"109124","DOI":"10.1016\/j.mbs.2023.109124","volume":"368","author":"R Marchello","year":"2024","unstructured":"Marchello R, Colombi A, Preziosi L, Giverso C (2024) A non local model for cell migration in response to mechanical stimuli. Math Biosci 368:109124. https:\/\/doi.org\/10.1016\/j.mbs.2023.109124","journal-title":"Math Biosci"},{"key":"12912_CR29","doi-asserted-by":"publisher","first-page":"47883","DOI":"10.1021\/acsomega.3c06436","volume":"8","author":"MI Taborda","year":"2023","unstructured":"Taborda MI, Catalan KN, Orellana N et al (2023) Micropatterned Nanofiber Scaffolds of Salmon Gelatin, Chitosan, and Poly(vinyl alcohol) for Muscle Tissue Engineering. ACS Omega 8:47883\u201347896. https:\/\/doi.org\/10.1021\/acsomega.3c06436","journal-title":"ACS Omega"},{"key":"12912_CR30","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1126\/sciadv.abe7204","volume":"7","author":"H Liu","year":"2021","unstructured":"Liu H, Usprech JF, Parameshwar PK et al (2021) Combinatorial screen of dynamic mechanical stimuli for predictive control of MSC mechano-responsiveness. Sci Adv 7:720. https:\/\/doi.org\/10.1126\/sciadv.abe7204","journal-title":"Sci Adv"},{"key":"12912_CR31","doi-asserted-by":"publisher","first-page":"3660","DOI":"10.1021\/acssensors.4c00756","volume":"9","author":"G Niraula","year":"2024","unstructured":"Niraula G, Pyne A, Wang X (2024) Develop Tandem Tension Sensor to Gauge Integrin-Transmitted Molecular Forces. ACS Sens 9:3660\u20133670. https:\/\/doi.org\/10.1021\/acssensors.4c00756","journal-title":"ACS Sens"},{"key":"12912_CR32","doi-asserted-by":"publisher","first-page":"2510","DOI":"10.1038\/s41467-021-22606-1","volume":"12","author":"T Schlichthaerle","year":"2021","unstructured":"Schlichthaerle T, Lindner C, Jungmann R (2021) Super-resolved visualization of single DNA-based tension sensors in cell adhesion. Nat Commun 12:2510. https:\/\/doi.org\/10.1038\/s41467-021-22606-1","journal-title":"Nat Commun"},{"key":"12912_CR33","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1002\/term.3188","volume":"15","author":"C Lui","year":"2021","unstructured":"Lui C, Chin AF, Park S et al (2021) Mechanical stimulation enhances development of scaffold-free, 3D-printed, engineered heart tissue grafts. J Tissue Eng Regen Med 15:503\u2013512. https:\/\/doi.org\/10.1002\/term.3188","journal-title":"J Tissue Eng Regen Med"},{"key":"12912_CR34","doi-asserted-by":"publisher","first-page":"52","DOI":"10.3390\/jfb17010052","volume":"17","author":"F Fouladgar","year":"2026","unstructured":"Fouladgar F, Powell R, Carney E et al (2026) Biomechanical Stimulation of Mesenchymal Stem Cells in 3D Peptide Nanofibers for Bone Differentiation. J Funct Biomater 17:52. https:\/\/doi.org\/10.3390\/jfb17010052","journal-title":"J Funct Biomater"},{"key":"12912_CR35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s42003-026-09514-0","volume":"9","author":"S Aytekin","year":"2026","unstructured":"Aytekin S, Kimps L, Coucke Q et al (2026) Linking molecular tension and cellular tractions: a multiscale approach to focal adhesion mechanics. Commun Biol 9:1\u201313. https:\/\/doi.org\/10.1038\/s42003-026-09514-0","journal-title":"Commun Biol"},{"key":"12912_CR36","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1021\/jacsau.4c00002","volume":"4","author":"S Wu","year":"2024","unstructured":"Wu S, Tang W, Wang Z et al (2024) High Dynamic Range Probing of Single-Molecule Mechanical Force Transitions at Cell\u2013Matrix Adhesion Bonds by a Plasmonic Tension Nanosensor. JACS Au 4:1155\u20131165. https:\/\/doi.org\/10.1021\/jacsau.4c00002","journal-title":"JACS Au"},{"key":"12912_CR37","doi-asserted-by":"publisher","first-page":"2197","DOI":"10.1038\/s41467-022-29823-2","volume":"13","author":"A Braeutigam","year":"2022","unstructured":"Braeutigam A, Simsek AN, Gompper G, Sabass B (2022) Generic self-stabilization mechanism for biomolecular adhesions under load. Nat Commun 13:2197. https:\/\/doi.org\/10.1038\/s41467-022-29823-2","journal-title":"Nat Commun"},{"key":"12912_CR38","doi-asserted-by":"publisher","first-page":"19064","DOI":"10.1021\/acsnano.4c03743","volume":"18","author":"E Sarikhani","year":"2024","unstructured":"Sarikhani E, Meganathan DP, Larsen AKK et al (2024) Engineering the Cellular Microenvironment: Integrating Three-Dimensional Nontopographical and Two-Dimensional Biochemical Cues for Precise Control of Cellular Behavior. ACS Nano 18:19064\u201319076. https:\/\/doi.org\/10.1021\/acsnano.4c03743","journal-title":"ACS Nano"},{"key":"12912_CR39","doi-asserted-by":"publisher","first-page":"2405","DOI":"10.1021\/acsapm.3c03154","volume":"6","author":"AM Smith","year":"2024","unstructured":"Smith AM, Inocencio DG, Pardi BM et al (2024) Facile Determination of the Poisson\u2019s Ratio and Young\u2019s Modulus of Polyacrylamide Gels and Polydimethylsiloxane. ACS Appl Polym Mater 6:2405\u20132416. https:\/\/doi.org\/10.1021\/acsapm.3c03154","journal-title":"ACS Appl Polym Mater"},{"key":"12912_CR40","doi-asserted-by":"publisher","first-page":"10789","DOI":"10.1021\/la300978x","volume":"28","author":"Y Sun","year":"2012","unstructured":"Sun Y, Jiang LT, Okada R, Fu J (2012) UV-modulated substrate rigidity for multiscale study of mechanoresponsive cellular behaviors. Langmuir 28:10789\u201310796. https:\/\/doi.org\/10.1021\/la300978x","journal-title":"Langmuir"},{"key":"12912_CR41","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1016\/j.cell.2006.06.044","volume":"126","author":"AJ Engler","year":"2006","unstructured":"Engler AJ, Sen S, Sweeney HL, Discher DE (2006) Matrix Elasticity Directs Stem Cell Lineage Specification. Cell 126:677\u2013689. https:\/\/doi.org\/10.1016\/j.cell.2006.06.044","journal-title":"Cell"},{"key":"12912_CR42","doi-asserted-by":"publisher","first-page":"110557","DOI":"10.1016\/j.isci.2024.110557","volume":"27","author":"J Llewellyn","year":"2024","unstructured":"Llewellyn J, Charrier A, Cuciniello R et al (2024) Substrate stiffness alters layer architecture and biophysics of human induced pluripotent stem cells to modulate their differentiation potential. iScience 27:110557. https:\/\/doi.org\/10.1016\/j.isci.2024.110557","journal-title":"iScience"},{"key":"12912_CR43","doi-asserted-by":"publisher","first-page":"3828","DOI":"10.1021\/acsbiomaterials.8b01124","volume":"5","author":"S Xia","year":"2019","unstructured":"Xia S, Yim EKF, Kanchanawong P (2019) Molecular Organization of Integrin-Based Adhesion Complexes in Mouse Embryonic Stem Cells. ACS Biomater Sci Eng 5:3828\u20133842. https:\/\/doi.org\/10.1021\/acsbiomaterials.8b01124","journal-title":"ACS Biomater Sci Eng"},{"key":"12912_CR44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/jbm.b.35462","volume":"112","author":"A Gupta","year":"2024","unstructured":"Gupta A, Barui A, Banerjee RK et al (2024) A multiscale modeling to determine in vitro mechanical responses of different cells at the cell-substrate interface under fluid perfusion. J Biomed Mater Res B Appl Biomater 112:1\u201316. https:\/\/doi.org\/10.1002\/jbm.b.35462","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"12912_CR45","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.1038\/s41586-025-08756-y","volume":"641","author":"J Zhang","year":"2025","unstructured":"Zhang J, Ali MY, Chong HB et al (2025) Oxidation of retromer complex controls mitochondrial translation. Nature 641:1048\u20131058. https:\/\/doi.org\/10.1038\/s41586-025-08756-y","journal-title":"Nature"},{"key":"12912_CR46","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1021\/acsbiomaterials.6b00058","volume":"2","author":"K Uto","year":"2016","unstructured":"Uto K, Mano SS, Aoyagi T, Ebara M (2016) Substrate Fluidity Regulates Cell Adhesion and Morphology on Poly(\u03b5-caprolactone)-Based Materials. ACS Biomater Sci Eng 2:446\u2013453. https:\/\/doi.org\/10.1021\/acsbiomaterials.6b00058","journal-title":"ACS Biomater Sci Eng"},{"key":"12912_CR47","doi-asserted-by":"publisher","first-page":"eabc2648","DOI":"10.1126\/sciadv.abc2648","volume":"6","author":"M Hippler","year":"2020","unstructured":"Hippler M, Wei\u00dfenbruch K, Richler K et al (2020) Mechanical stimulation of single cells by reversible host-guest interactions in 3D microscaffolds. Sci Adv 6:eabc2648. https:\/\/doi.org\/10.1126\/sciadv.abc2648","journal-title":"Sci Adv"},{"key":"12912_CR48","doi-asserted-by":"publisher","unstructured":"Man K, Liu J, Phan KM et al (2022) Dimensionality-Dependent Mechanical Stretch Regulation of Cell Behavior. ACS Appl Mater Interfaces 14:17081\u201317092. https:\/\/doi.org\/10.1021\/acsami.2c01266","DOI":"10.1021\/acsami.2c01266"},{"key":"12912_CR49","doi-asserted-by":"publisher","unstructured":"Hong Y, Peng X, Yu H et al (2025) Cell \u2013 matrix feedback controls stretch - induced cellular memory and fibroblast activation. Proc Natl Acad Sci 122:e2322762122. https:\/\/doi.org\/10.1073\/pnas.2322762122","DOI":"10.1073\/pnas.2322762122"},{"key":"12912_CR50","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1109\/iembs.2002.1134503","volume":"1","author":"SA Metzler","year":"2002","unstructured":"Metzler SA, Hucker WJ, Yin FCP (2002) Effect of mechanical stretch and shortening on the stiffness of human aortic endothelial cells. Annual Int Conf IEEE Eng Med Biology - Proc 1:300\u2013301. https:\/\/doi.org\/10.1109\/iembs.2002.1134503","journal-title":"Annual Int Conf IEEE Eng Med Biology - Proc"},{"key":"12912_CR51","doi-asserted-by":"publisher","first-page":"e23272","DOI":"10.1371\/journal.pone.0023272","volume":"6","author":"AM Quinlan","year":"2011","unstructured":"Quinlan AM, Sierad LN, Capulli AK et al (2011) Combining dynamic stretch and tunable stiffness to probe cell mechanobiology in vitro. PLoS ONE 6:e23272. https:\/\/doi.org\/10.1371\/journal.pone.0023272","journal-title":"PLoS ONE"},{"key":"12912_CR52","doi-asserted-by":"publisher","first-page":"8751","DOI":"10.1038\/s41467-024-52742-3","volume":"15","author":"W Li","year":"2024","unstructured":"Li W, Moretti L, Su X et al (2024) Strain-dependent glutathionylation of fibronectin fibers impacts mechano-chemical behavior and primes an integrin switch. Nat Commun 15:8751. https:\/\/doi.org\/10.1038\/s41467-024-52742-3","journal-title":"Nat Commun"},{"key":"12912_CR53","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fcell.2021.712627","volume":"9","author":"LA P\u00e9rez","year":"2021","unstructured":"P\u00e9rez LA, Rashid A, Combs JD et al (2021) An Outside-In Switch in Integrin Signaling Caused by Chemical and Mechanical Signals in Reactive Astrocytes. Front Cell Dev Biol 9:1\u201314. https:\/\/doi.org\/10.3389\/fcell.2021.712627","journal-title":"Front Cell Dev Biol"},{"key":"12912_CR54","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/adma.202309284","volume":"36","author":"K Jain","year":"2024","unstructured":"Jain K, Pandey A, Wang H et al (2024) TiO2 Nano-Biopatterning Reveals Optimal Ligand Presentation for Cell\u2013Matrix Adhesion Formation. Adv Mater 36:1\u201313. https:\/\/doi.org\/10.1002\/adma.202309284","journal-title":"Adv Mater"},{"key":"12912_CR55","doi-asserted-by":"publisher","unstructured":"Mason DE, Collins JM, Dawahare JH et al (2019) YAP and TAZ limit cytoskeletal and focal adhesion maturation to enable persistent cell motility. J Cell Biol 218:1369\u20131389. https:\/\/doi.org\/10.1083\/jcb.201806065","DOI":"10.1083\/jcb.201806065"},{"key":"12912_CR56","doi-asserted-by":"publisher","first-page":"112835","DOI":"10.1016\/j.yexcr.2021.112835","volume":"408","author":"E Matsuo","year":"2021","unstructured":"Matsuo E, Okamoto T, Ito A et al (2021) Substrate stiffness modulates endothelial cell function via the YAP-Dll4-Notch1 pathway. Exp Cell Res 408:112835. https:\/\/doi.org\/10.1016\/j.yexcr.2021.112835","journal-title":"Exp Cell Res"},{"key":"12912_CR57","doi-asserted-by":"publisher","first-page":"122542","DOI":"10.1016\/j.biomaterials.2024.122542","volume":"308","author":"EN Holland","year":"2024","unstructured":"Holland EN, Fern\u00e1ndez-Yag\u00fce MA, Zhou DW et al (2024) FAK, vinculin, and talin control mechanosensitive YAP nuclear localization. Biomaterials 308:122542. https:\/\/doi.org\/10.1016\/j.biomaterials.2024.122542","journal-title":"Biomaterials"},{"key":"12912_CR58","doi-asserted-by":"publisher","first-page":"123512","DOI":"10.1016\/j.biomaterials.2025.123512","volume":"324","author":"F Mauro","year":"2026","unstructured":"Mauro F, Natale CF, Panzetta V et al (2026) Biomaterials Regulation of nuclear deformation via spatiotemporal modulation of cytoskeleton forces on photo-switchable surfaces. Biomaterials 324:123512. https:\/\/doi.org\/10.1016\/j.biomaterials.2025.123512","journal-title":"Biomaterials"},{"key":"12912_CR59","doi-asserted-by":"publisher","first-page":"4279","DOI":"10.1021\/acs.nanolett.4c00732","volume":"24","author":"J Buisson","year":"2024","unstructured":"Buisson J, Zhang X, Zambelli T et al (2024) Reverse Mechanotransduction: Driving Chromatin Compaction to Decompaction Increases Cell Adhesion Strength and Contractility. Nano Lett 24:4279\u20134290. https:\/\/doi.org\/10.1021\/acs.nanolett.4c00732","journal-title":"Nano Lett"},{"key":"12912_CR60","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1126\/sciadv.aay3909","volume":"6","author":"E-Y Shin","year":"2020","unstructured":"Shin E-Y, Park J-H, You S-T et al (2020) Integrin-mediated adhesions in regulation of cellular senescence. Sci Adv 6:1\u201311. https:\/\/doi.org\/10.1126\/sciadv.aay3909","journal-title":"Sci Adv"},{"key":"12912_CR61","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1038\/s12276-023-00966-6","volume":"55","author":"JJ Park","year":"2023","unstructured":"Park JJ, Oh K, Lee GW et al (2023) Defining regorafenib as a senomorphic drug: therapeutic potential in the age-related lung disease emphysema. Exp Mol Med 55:794\u2013805. https:\/\/doi.org\/10.1038\/s12276-023-00966-6","journal-title":"Exp Mol Med"},{"key":"12912_CR62","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1038\/s41419-022-05020-3","volume":"13","author":"C Ji","year":"2022","unstructured":"Ji C, Zhang M, Hu J et al (2022) The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer. Cell Death Dis 13:577. https:\/\/doi.org\/10.1038\/s41419-022-05020-3","journal-title":"Cell Death Dis"},{"key":"12912_CR63","doi-asserted-by":"publisher","first-page":"1398","DOI":"10.1038\/s41418-024-01333-2","volume":"31","author":"JJ Park","year":"2024","unstructured":"Park JJ, Lee SJ, Baek M et al (2024) FRMD6 determines the cell fate towards senescence: involvement of the Hippo-YAP-CCN3 axis. Cell Death Differ 31:1398\u20131409. https:\/\/doi.org\/10.1038\/s41418-024-01333-2","journal-title":"Cell Death Differ"},{"key":"12912_CR64","doi-asserted-by":"publisher","unstructured":"Kolasangiani R, Farzanian K, Chen Y et al (2025) Conformational response of \u03b1IIb\u03b23 and \u03b1V\u03b23 integrins to force. Structure 33:289\u2013299. https:\/\/doi.org\/10.1016\/j.str.2024.11.016","DOI":"10.1016\/j.str.2024.11.016"},{"key":"12912_CR65","doi-asserted-by":"publisher","unstructured":"Swaminathan V, Bidone TC (2025) Stabilization of adhesions controls F-actin architecture in mechanotransduction.Commun Mater 6:288. https:\/\/doi.org\/10.1038\/s43246-025-01006-8","DOI":"10.1038\/s43246-025-01006-8"},{"key":"12912_CR66","doi-asserted-by":"publisher","first-page":"5897","DOI":"10.1039\/d0na00623h","volume":"2","author":"F Valle","year":"2020","unstructured":"Valle F, Tortorella S, Scala A et al (2020) Amphiphilic cationic cyclodextrin nanovesicles: A versatile cue for guiding cell adhesion. Nanoscale Adv 2:5897\u20135904. https:\/\/doi.org\/10.1039\/d0na00623h","journal-title":"Nanoscale Adv"},{"key":"12912_CR67","doi-asserted-by":"publisher","first-page":"7241","DOI":"10.1021\/acs.jpcb.1c01347","volume":"125","author":"P Kumari","year":"2021","unstructured":"Kumari P, Faraone A, Kelley EG, Benedetto A (2021) Stiffening Effect of the [Bmim][Cl] Ionic Liquid on the Bending Dynamics of DMPC Lipid Vesicles. J Phys Chem B 125:7241\u20137250. https:\/\/doi.org\/10.1021\/acs.jpcb.1c01347","journal-title":"J Phys Chem B"},{"key":"12912_CR68","doi-asserted-by":"publisher","first-page":"e20200419","DOI":"10.1083\/jcb.20200419812072020c","volume":"219","author":"M Benito-Jard\u00f3n","year":"2021","unstructured":"Benito-Jard\u00f3n M, Strohmeyer N, Otega-Sanch\u00eds S et al (2021) Correction: \u03b1v-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation. J Cell Biol 219:e20200419. https:\/\/doi.org\/10.1083\/jcb.20200419812072020c","journal-title":"J Cell Biol"},{"key":"12912_CR69","doi-asserted-by":"publisher","first-page":"14348","DOI":"10.1038\/ncomms14348","volume":"8","author":"M Bharadwaj","year":"2017","unstructured":"Bharadwaj M, Strohmeyer N, Colo GP et al (2017) \u03b1V-class integrins exert dual roles on \u03b15\u03b21 integrins to strengthen adhesion to fibronectin. Nat Commun 8:14348. https:\/\/doi.org\/10.1038\/ncomms14348","journal-title":"Nat Commun"},{"key":"12912_CR70","doi-asserted-by":"publisher","unstructured":"Zhuo P, Li Q, Yang B et al (2025) Interaction of integrin \u03b1v\u03b23 and fibronectin under fluid shear forces: implications for tumor cell adhesion and migration. Front Cell Dev Biol 13:1\u201312. https:\/\/doi.org\/10.3389\/fcell.2025.1512672","DOI":"10.3389\/fcell.2025.1512672"},{"key":"12912_CR71","doi-asserted-by":"publisher","first-page":"7110","DOI":"10.1021\/acsnano.7b02755","volume":"11","author":"L Cao","year":"2017","unstructured":"Cao L, Nicosia J, Larouche J et al (2017) Detection of an Integrin-Binding Mechanoswitch within Fibronectin during Tissue Formation and Fibrosis. ACS Nano 11:7110\u20137117. https:\/\/doi.org\/10.1021\/acsnano.7b02755","journal-title":"ACS Nano"},{"key":"12912_CR72","doi-asserted-by":"publisher","first-page":"e0218893","DOI":"10.1371\/journal.pone.0218893","volume":"14","author":"G Yalak","year":"2019","unstructured":"Yalak G, Shiu J-Y, Schoen I et al (2019) Phosphorylated fibronectin enhances cell attachment and upregulates mechanical cell functions. PLoS ONE 14:e0218893. https:\/\/doi.org\/10.1371\/journal.pone.0218893","journal-title":"PLoS ONE"},{"key":"12912_CR73","doi-asserted-by":"publisher","unstructured":"Liu X, Liu J, Wang Y et al (2025) The mechanical response of vinculin. Sci Adv 11:6949. https:\/\/doi.org\/10.1126\/sciadv.ady6949","DOI":"10.1126\/sciadv.ady6949"},{"key":"12912_CR74","doi-asserted-by":"publisher","unstructured":"Deng W, Carr RL, Kaul RR et al (2025) Consolidation of cell-ECM adhesion through direct talin-mediated actin linkage is essential for mouse embryonic morphogenesis. Commun Biol 8:948. https:\/\/doi.org\/10.1038\/s42003-025-08294-3","DOI":"10.1038\/s42003-025-08294-3"},{"key":"12912_CR75","doi-asserted-by":"publisher","first-page":"7509","DOI":"10.1021\/acs.langmuir.8b02841","volume":"35","author":"RJ Leiphart","year":"2019","unstructured":"Leiphart RJ, Chen D, Peredo AP et al (2019) Mechanosensing at Cellular Interfaces. Langmuir 35:7509\u20137519. https:\/\/doi.org\/10.1021\/acs.langmuir.8b02841","journal-title":"Langmuir"},{"key":"12912_CR76","doi-asserted-by":"publisher","first-page":"5307","DOI":"10.1021\/acs.langmuir.1c03048","volume":"38","author":"AC Chang","year":"2022","unstructured":"Chang AC, Uto K, Abdellatef SA, Nakanishi J (2022) Precise Tuning and Characterization of Viscoelastic Interfaces for the Study of Early Epithelial-Mesenchymal Transition Behaviors. Langmuir 38:5307\u20135314. https:\/\/doi.org\/10.1021\/acs.langmuir.1c03048","journal-title":"Langmuir"},{"key":"12912_CR77","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1016\/j.bpj.2022.01.006","volume":"121","author":"Q Yu","year":"2022","unstructured":"Yu Q, Holmes WR, Thiery JP et al (2022) Cortical tension initiates the positive feedback loop between cadherin and F-actin. Biophys J 121:596\u2013606. https:\/\/doi.org\/10.1016\/j.bpj.2022.01.006","journal-title":"Biophys J"},{"key":"12912_CR78","doi-asserted-by":"publisher","first-page":"113353","DOI":"10.1016\/j.jbiomech.2026.113353","volume":"204","author":"R Ganguly","year":"2026","unstructured":"Ganguly R, Choudhury S, Gupta A et al (2026) Finite element modelling for elucidating surface topography influence on cell-substrate interaction on fatty acid-modified PCL substrate. J Biomech 204:113353. https:\/\/doi.org\/10.1016\/j.jbiomech.2026.113353","journal-title":"J Biomech"},{"key":"12912_CR79","doi-asserted-by":"publisher","unstructured":"Caluori G, Pribyl J, Pesl M et al (2018) Advanced and Rationalized Atomic Force Microscopy Analysis Unveils Specific Properties of Controlled Cell Mechanics. Front Physiol 9:1121. https:\/\/doi.org\/10.3389\/fphys.2018.01121","DOI":"10.3389\/fphys.2018.01121"},{"key":"12912_CR80","doi-asserted-by":"publisher","first-page":"5847","DOI":"10.1021\/acs.biomac.3c00871","volume":"24","author":"H Xu","year":"2023","unstructured":"Xu H, Duan S, Hu Y et al (2023) Rapid Regulation of Cardiomyocytes Adhesion on Substrates with Varied Modulus via Mechanical Cues. Biomacromolecules 24:5847\u20135858. https:\/\/doi.org\/10.1021\/acs.biomac.3c00871","journal-title":"Biomacromolecules"},{"key":"12912_CR81","doi-asserted-by":"publisher","first-page":"e1011500","DOI":"10.1371\/journal.pcbi.1011500","volume":"19","author":"KS Honasoge","year":"2023","unstructured":"Honasoge KS, Karag\u00f6z Z, Goult BT et al (2023) Force-dependent focal adhesion assembly and disassembly: A computational study. PLoS Comput Biol 19:e1011500. https:\/\/doi.org\/10.1371\/journal.pcbi.1011500","journal-title":"PLoS Comput Biol"},{"key":"12912_CR82","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1016\/j.molcel.2019.06.012","volume":"75","author":"PD Zamore","year":"2020","unstructured":"Becker WR, Ober-Reynolds B, Jouravleva K, Jolly SM, Zamore PD, Greenleaf WJ. (2020) High-Throughput Analysis Reveals Rules for Target RNA Binding and Cleavage by AGO2. Mol Cell 75:741\u2013755. https:\/\/doi.org\/10.1016\/j.molcel.2019.06.012","journal-title":"Mol Cell"},{"key":"12912_CR83","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1016\/j.actbio.2020.12.014","volume":"121","author":"S Deguchi","year":"2021","unstructured":"Deguchi S, Kato A, Wu P et al (2021) Heterogeneous role of integrins in fibroblast response to small cyclic mechanical stimulus generated by a nanoporous gold actuator. Acta Biomater 121:418\u2013430. https:\/\/doi.org\/10.1016\/j.actbio.2020.12.014","journal-title":"Acta Biomater"},{"key":"12912_CR84","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1126\/sciadv.abj4990","volume":"29","author":"K Miyazawa","year":"2023","unstructured":"Miyazawa K, Penedo M, Furusho H et al (2023) Nanoendoscopy-AFM for Visualizing Intracellular Nanostructures of Living Cells. Microsc Microanal 29:782. https:\/\/doi.org\/10.1126\/sciadv.abj4990","journal-title":"Microsc Microanal"},{"key":"12912_CR85","doi-asserted-by":"publisher","first-page":"5695","DOI":"10.1021\/acsabm.3c00833","volume":"6","author":"C-H Lin","year":"2023","unstructured":"Lin C-H, Tang X, Chen P, Luo S-C (2023) Unraveling the Adhesion Behavior of Different Cell Lines on Biomimetic PEDOT Interfaces: The Role of Surface Morphology and Antifouling Properties. ACS Appl Bio Mater 6:5695\u20135707. https:\/\/doi.org\/10.1021\/acsabm.3c00833","journal-title":"ACS Appl Bio Mater"},{"key":"12912_CR86","doi-asserted-by":"publisher","first-page":"7331","DOI":"10.1038\/s41467-023-43225-y","volume":"14","author":"A Joshi","year":"2023","unstructured":"Joshi A, Walimbe A, Avni A et al (2023) Single-molecule FRET unmasks structural subpopulations and crucial molecular events during FUS low-complexity domain phase separation. Nat Commun 14:7331. https:\/\/doi.org\/10.1038\/s41467-023-43225-y","journal-title":"Nat Commun"},{"key":"12912_CR87","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11249-024-01952-3","volume":"73","author":"G Violano","year":"2025","unstructured":"Violano G, Demelio GP, Afferrante L (2025) Sliding Viscoelastic Contacts: Reciprocating Adhesive Contact Mechanics and Hysteretic Loss. Tribol Lett 73:1\u201310. https:\/\/doi.org\/10.1007\/s11249-024-01952-3","journal-title":"Tribol Lett"},{"key":"12912_CR88","doi-asserted-by":"publisher","unstructured":"Zhu J, Tian Y, Tian L et al (2020) Mechanobiology Analysis of Manifold Live Cells in Vitro with Atomic Force Acoustic Microscopy. ACS Appl Bio Mater 3:1210\u20131215. https:\/\/doi.org\/10.1021\/acsabm.9b01105","DOI":"10.1021\/acsabm.9b01105"},{"key":"12912_CR89","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1021\/acs.langmuir.1c01973","volume":"38","author":"M Luo","year":"2022","unstructured":"Luo M, Yang W, Cartwright TN et al (2022) Simultaneous Measurement of Single-Cell Mechanics and Cell-to-Materials Adhesion Using Fluidic Force Microscopy. Langmuir 38:620\u2013628. https:\/\/doi.org\/10.1021\/acs.langmuir.1c01973","journal-title":"Langmuir"},{"key":"12912_CR90","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1021\/acsbiomaterials.9b01189","volume":"6","author":"S Paiva","year":"2020","unstructured":"Paiva S, Joanne P, Migdal C et al (2020) Polyacrylamide Hydrogels with Rigidity-Independent Surface Chemistry Show Limited Long-Term Maintenance of Pluripotency of Human Induced Pluripotent Stem Cells on Soft Substrates. ACS Biomater Sci Eng 6:340\u2013351. https:\/\/doi.org\/10.1021\/acsbiomaterials.9b01189","journal-title":"ACS Biomater Sci Eng"},{"key":"12912_CR91","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1038\/s43246-024-00444-0","volume":"5","author":"N Mittal","year":"2024","unstructured":"Mittal N, Michels EB, Massey AE et al (2024) Myosin-independent stiffness sensing by fibroblasts is regulated by the viscoelasticity of flowing actin. Commun Mater 5:6. https:\/\/doi.org\/10.1038\/s43246-024-00444-0","journal-title":"Commun Mater"},{"key":"12912_CR92","doi-asserted-by":"publisher","first-page":"114351","DOI":"10.1016\/j.matdes.2025.114351","volume":"256","author":"Y Li","year":"2025","unstructured":"Li Y, Shi J, Li G et al (2025) Roughness-driven compressive sensing AFM for accurate nanoscale surface characterization in functional material systems. Mater Des 256:114351. https:\/\/doi.org\/10.1016\/j.matdes.2025.114351","journal-title":"Mater Des"}],"container-title":["Molecular Biology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-026-12912-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11033-026-12912-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-026-12912-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T10:09:46Z","timestamp":1792231786000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11033-026-12912-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,17]]},"references-count":92,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["12912"],"URL":"https:\/\/doi.org\/10.1007\/s11033-026-12912-6","relation":{},"ISSN":["0301-4851","1573-4978"],"issn-type":[{"value":"0301-4851","type":"print"},{"value":"1573-4978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,17]]},"assertion":[{"value":"5 May 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.The authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interestsCompeting interests","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":3,"name":"Ethics","label":"Consent to Participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors agreed to submit the manuscript for publication.","order":4,"name":"Ethics","label":"Consent to Publish","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"1756"}}