{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T08:43:09Z","timestamp":1788252189133,"version":"build-2803163510"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2019,2,25]],"date-time":"2019-02-25T00:00:00Z","timestamp":1551052800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100005153","name":"China National Funds for Distinguished Young Scientists","doi-asserted-by":"publisher","award":["81571971"],"award-info":[{"award-number":["81571971"]}],"id":[{"id":"10.13039\/501100005153","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005153","name":"China National Funds for Distinguished Young Scientists","doi-asserted-by":"publisher","award":["81271804"],"award-info":[{"award-number":["81271804"]}],"id":[{"id":"10.13039\/501100005153","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004607","name":"Natural Science Foundation of Guangxi Province","doi-asserted-by":"publisher","award":["2017GXNSFAA198004"],"award-info":[{"award-number":["2017GXNSFAA198004"]}],"id":[{"id":"10.13039\/501100004607","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004607","name":"Natural Science Foundation of Guangxi Province","doi-asserted-by":"publisher","award":["20150825"],"award-info":[{"award-number":["20150825"]}],"id":[{"id":"10.13039\/501100004607","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mycopathologia"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1007\/s11046-019-00325-y","type":"journal-article","created":{"date-parts":[[2019,2,25]],"date-time":"2019-02-25T04:24:49Z","timestamp":1551068689000},"page":"295-301","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["In Vitro Susceptibility of Berberine Combined with Antifungal Agents Against the Yeast Form of Talaromyces marneffei"],"prefix":"10.1007","volume":"184","author":[{"given":"Hong","family":"Luo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai-su","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-lu","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-yan","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Andrianopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le-min","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-qing","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-yang","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiu-ying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-jiao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian-min","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Joseph","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cun-wei","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,2,25]]},"reference":[{"issue":"8915","key":"325_CR1","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/S0140-6736(94)91287-4","volume":"344","author":"K Supparatpinyo","year":"1994","unstructured":"Supparatpinyo K, Khamwan C, Baosoung V, Nelson KE, Sirisanthana T. Disseminated Penicillium marneffei infection in southeast Asia. Lancet. 1994;344(8915):110\u20133.","journal-title":"Lancet"},{"issue":"1\u20132","key":"325_CR2","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1007\/s11046-012-9577-0","volume":"175","author":"Y Hu","year":"2013","unstructured":"Hu Y, Zhang J, Li X, Yang Y, Zhang Y, Ma J, et al. Penicillium marneffei infection: an emerging disease in mainland China. Mycopathologia. 2013;175(1\u20132):57\u201367. \n                    https:\/\/doi.org\/10.1007\/s11046-012-9577-0\n                    \n                  .","journal-title":"Mycopathologia"},{"issue":"3\u20134","key":"325_CR3","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/s11046-014-9787-8","volume":"178","author":"D Mo","year":"2014","unstructured":"Mo D, Li X, Wei L, Sun C, Liang H, Cao C. In vitro interactions of calcineurin inhibitors with conventional antifungal agents against the yeast form of Penicillium marneffei. Mycopathologia. 2014;178(3\u20134):217\u201320. \n                    https:\/\/doi.org\/10.1007\/s11046-014-9787-8\n                    \n                  .","journal-title":"Mycopathologia"},{"issue":"2","key":"325_CR4","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1093\/jac\/dkn494","volume":"63","author":"C Cao","year":"2009","unstructured":"Cao C, Liu W, Li R, Wan Z, Qiao J. In vitro interactions of micafungin with amphotericin B, itraconazole or fluconazole against the pathogenic phase of Penicillium marneffei. J Antimicrob Chemother. 2009;63(2):340\u20132. \n                    https:\/\/doi.org\/10.1093\/jac\/dkn494\n                    \n                  .","journal-title":"J Antimicrob Chemother"},{"key":"325_CR5","first-page":"741","volume":"7","author":"Y Chang","year":"1959","unstructured":"Chang Y. Effectiveness of berberine in bacillary dysentery. Zhonghua nei ke za zhi. 1959;7:741\u20133.","journal-title":"Zhonghua nei ke za zhi"},{"issue":"5","key":"325_CR6","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1142\/S0192415X14500669","volume":"42","author":"C Chen","year":"2014","unstructured":"Chen C, Yu Z, Li Y, Fichna J, Storr M. Effects of berberine in the gastrointestinal tract a review of actions and therapeutic implications. Am J Chin Med. 2014;42(5):1053\u201370. \n                    https:\/\/doi.org\/10.1142\/S0192415X14500669\n                    \n                  .","journal-title":"Am J Chin Med"},{"issue":"10","key":"325_CR7","doi-asserted-by":"publisher","first-page":"e109863","DOI":"10.1371\/journal.pone.0109863","volume":"9","author":"S Bang","year":"2014","unstructured":"Bang S, Kwon H, Hwang HS, Park KD, Kim SU, Bahn YS. 9-O-butyl-13-(4-isopropylbenzyl)berberine, KR-72, is a potent antifungal agent that inhibits the growth of Cryptococcus neoformans by regulating gene expression. PLoS ONE. 2014;9(10):e109863. \n                    https:\/\/doi.org\/10.1371\/journal.pone.0109863\n                    \n                  .","journal-title":"PLoS ONE"},{"issue":"3","key":"325_CR8","doi-asserted-by":"publisher","first-page":"1096","DOI":"10.1128\/AAC.50.3.1096-1099.2006","volume":"50","author":"H Quan","year":"2006","unstructured":"Quan H, Cao YY, Xu Z, Zhao JX, Gao PH, Qin XF, et al. Potent in vitro synergism of fluconazole and berberine chloride against clinical isolates of Candida albicans resistant to fluconazole. Antimicrob Agents Chemother. 2006;50(3):1096\u20139. \n                    https:\/\/doi.org\/10.1128\/AAC.50.3.1096-1099.2006\n                    \n                  .","journal-title":"Antimicrob Agents Chemother"},{"key":"325_CR9","unstructured":"Wayne (2008) Clinical and Laboratory Standards Institute (CLSI). Reference method for broth dilution antifungal susceptibility testing of yeasts. Approved standard, 3rd edn"},{"issue":"6","key":"325_CR10","doi-asserted-by":"publisher","first-page":"1392","DOI":"10.1128\/AAC.41.6.1392","volume":"41","author":"ME Klepser","year":"1997","unstructured":"Klepser ME, Wolfe EJ, Jones RN, Nightingale CH, Pfaller MA. Antifungal pharmacodynamic characteristics of fluconazole and amphotericin B tested against Candida albicans. Antimicrob Agents Chemother. 1997;41(6):1392\u20135.","journal-title":"Antimicrob Agents Chemother"},{"issue":"2","key":"325_CR11","first-page":"65","volume":"13","author":"Ning Xin-qiang CC-w","year":"2018","unstructured":"Ning Xin-qiang CC-w. Effects of SakA on the drug stress and virulence in Talaromyces marneffei. Chin J Mycol. 2018;13(2):65\u201370.","journal-title":"Chin J Mycol"},{"issue":"6","key":"325_CR12","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1016\/0022-3913(90)90298-Q","volume":"64","author":"K Nakamoto","year":"1990","unstructured":"Nakamoto K, Sadamori S, Hamada T. Effects of crude drugs and berberine hydrochloride on the activities of fungi. J Prosthet Dent. 1990;64(6):691\u20134.","journal-title":"J Prosthet Dent"},{"issue":"1","key":"325_CR13","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1177\/0022034511399286","volume":"23","author":"X Liu","year":"2011","unstructured":"Liu X, Han Y, Peng K, Liu Y, Li J, Liu H. Effect of traditional Chinese medicinal herbs on Candida spp. from patients with HIV\/AIDS. Adv Dent Res. 2011;23(1):56\u201360. \n                    https:\/\/doi.org\/10.1177\/0022034511399286\n                    \n                  .","journal-title":"Adv Dent Res"},{"issue":"3","key":"325_CR14","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1248\/bpb.28.541","volume":"28","author":"LEE Yhj-H","year":"2005","unstructured":"Yhj-H LEE. Berberine synergy with amphotericin B against disseminated candidiasis in mice. Biol Pharm Bull. 2005;28(3):541\u20134.","journal-title":"Biol Pharm Bull"},{"key":"325_CR15","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/j.biopha.2017.06.106","volume":"93","author":"G Shi","year":"2017","unstructured":"Shi G, Shao J, Wang T, Wu D, Wang C. Mechanism of berberine-mediated fluconazole-susceptibility enhancement in clinical fluconazole-resistant Candida tropicalis isolates. Biomed Pharmacother. 2017;93:709\u201312. \n                    https:\/\/doi.org\/10.1016\/j.biopha.2017.06.106\n                    \n                  .","journal-title":"Biomed Pharmacother"},{"issue":"1","key":"325_CR16","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.ijpharm.2018.04.014","volume":"544","author":"J Sun","year":"2018","unstructured":"Sun J, Bao H, Peng Y, Zhang H, Sun Y, Qi J, et al. Improvement of intestinal transport, absorption and anti-diabetic efficacy of berberine by using Gelucire44\/14: in vitro, in situ and in vivo studies. Int J Pharm. 2018;544(1):46\u201354. \n                    https:\/\/doi.org\/10.1016\/j.ijpharm.2018.04.014\n                    \n                  .","journal-title":"Int J Pharm"},{"key":"325_CR17","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1186\/1471-2334-13-464","volume":"13","author":"R Kawila","year":"2013","unstructured":"Kawila R, Chaiwarith R, Supparatpinyo K. Clinical and laboratory characteristics of penicilliosis marneffei among patients with and without HIV infection in Northern Thailand: a retrospective study. BMC Infect Dis. 2013;13:464. \n                    https:\/\/doi.org\/10.1186\/1471-2334-13-464\n                    \n                  .","journal-title":"BMC Infect Dis"},{"issue":"12","key":"325_CR18","doi-asserted-by":"publisher","first-page":"4535","DOI":"10.1128\/JCM.39.12.4535-4540.2001","volume":"39","author":"SS Wong","year":"2001","unstructured":"Wong SS, Wong KH, Hui WT, Lee SS, Lo JY, Cao L, et al. Differences in clinical and laboratory diagnostic characteristics of penicilliosis marneffei in human immunodeficiency virus (HIV)- and non-HIV-infected patients. J Clin Microbiol. 2001;39(12):4535\u201340. \n                    https:\/\/doi.org\/10.1128\/JCM.39.12.4535-4540.2001\n                    \n                  .","journal-title":"J Clin Microbiol"}],"container-title":["Mycopathologia"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11046-019-00325-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11046-019-00325-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11046-019-00325-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,22]],"date-time":"2019-09-22T13:42:09Z","timestamp":1569159729000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11046-019-00325-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,25]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["325"],"URL":"https:\/\/doi.org\/10.1007\/s11046-019-00325-y","relation":{},"ISSN":["0301-486X","1573-0832"],"issn-type":[{"value":"0301-486X","type":"print"},{"value":"1573-0832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,25]]},"assertion":[{"value":"8 November 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 February 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 February 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}