{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T18:04:28Z","timestamp":1751565868104,"version":"3.37.3"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"1-2","license":[{"start":{"date-parts":[[2023,1,7]],"date-time":"2023-01-07T00:00:00Z","timestamp":1673049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,1,7]],"date-time":"2023-01-07T00:00:00Z","timestamp":1673049600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mycopathologia"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1007\/s11046-022-00705-x","type":"journal-article","created":{"date-parts":[[2023,1,7]],"date-time":"2023-01-07T09:06:47Z","timestamp":1673082407000},"page":"51-61","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Genotypic Diversity and Antifungal Susceptibility of Clinical Isolates of Cryptococcus Gattii Species Complex from Argentina"],"prefix":"10.1007","volume":"188","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6985-2699","authenticated-orcid":false,"given":"Constanza Giselle","family":"Taverna","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara Abigail","family":"Arias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7547-5172","authenticated-orcid":false,"given":"Carolina","family":"Firacative","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mat\u00edas Ezequiel","family":"Vivot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanda","family":"Szusz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter","family":"Vivot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana","family":"Mazza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susana Beatriz","family":"C\u00f3rdoba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina Elena","family":"Canteros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,1,7]]},"reference":[{"key":"705_CR1","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.fgb.2015.02.009","volume":"78","author":"F Hagen","year":"2015","unstructured":"Hagen F, Khayhan K, Theelen B, Kolecka A, Polacheck I, Sionov E, et al. Recognition of seven species in the Cryptococcus gattii\/Cryptococcus neoformans species complex. Fungal Genet Biol. 2015;78:16\u201348.","journal-title":"Fungal Genet Biol"},{"key":"705_CR2","doi-asserted-by":"publisher","first-page":"e02306","DOI":"10.1128\/mBio.02306-19","volume":"10","author":"RA Farrer","year":"2019","unstructured":"Farrer RA, Chang M, Davis MJ, van Dorp L, Yang D-H, Shea T, et al. A new lineage of Cryptococcus gattii (VGV) discovered in the Central Zambezian Miombo Woodlands. MBio. 2019;10:e02306-19.","journal-title":"MBio"},{"key":"705_CR3","unstructured":"Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases. Cryptococcus gattii infection statistics [Internet]. https:\/\/www.cdc.gov\/fungal\/diseases\/cryptococcosis-gattii\/statistics.html. Accessed 4 May 2022"},{"key":"705_CR4","doi-asserted-by":"publisher","first-page":"42","DOI":"10.3201\/eid1301.060827","volume":"13","author":"L MacDougall","year":"2007","unstructured":"MacDougall L, Kidd SE, Galanis E, Mak S, Leslie MJ, Cieslak PR, et al. Spread of Cryptococcus gattii in British Columbia, Canada, and detection in the Pacific Northwest, USA. Emerg Infect Dis. 2007;13:42\u201350.","journal-title":"Emerg Infect Dis"},{"key":"705_CR5","doi-asserted-by":"publisher","first-page":"e1000850","DOI":"10.1371\/journal.ppat.1000850","volume":"6","author":"EJ Byrnes","year":"2010","unstructured":"Byrnes EJ, Li W, Lewit Y, Ma H, Voelz K, Ren P, et al. Emergence and pathogenicity of highly virulent Cryptococcus gattii genotypes in the northwest United States. PLoS Pathog. 2010;6:e1000850.","journal-title":"PLoS Pathog"},{"key":"705_CR6","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1016\/j.micinf.2011.05.009","volume":"13","author":"EJ Byrnes","year":"2011","unstructured":"Byrnes EJ, Bartlett KH, Perfect JR, Heitman J. Cryptococcus gattii: an emerging fungal pathogen infecting humans and animals. Microbes Infect. 2011;13:895\u2013907.","journal-title":"Microbes Infect"},{"key":"705_CR7","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1007\/s11908-011-0181-0","volume":"13","author":"EJ Byrnes","year":"2011","unstructured":"Byrnes EJ, Marr KA. The outbreak of Cryptococcus gattii in Western North America: epidemiology and clinical issues. Curr Infect Dis Rep. 2011;13:256\u201361.","journal-title":"Curr Infect Dis Rep"},{"key":"705_CR8","doi-asserted-by":"publisher","first-page":"1620","DOI":"10.3201\/eid1910.130441","volume":"19","author":"JR Harris","year":"2013","unstructured":"Harris JR, Lockhart SR, Sondermeyer G, Vugia DJ, Crist MB, D\u2019Angelo MT, et al. Cryptococcus gattii infections in multiple states outside the US Pacific Northwest. Emerg Infect Dis. 2013;19:1620\u20136.","journal-title":"Emerg Infect Dis"},{"key":"705_CR9","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1007\/s11046-011-9475-x","volume":"173","author":"KH Bartlett","year":"2012","unstructured":"Bartlett KH, Cheng P-Y, Duncan C, Galanis E, Hoang L, Kidd S, et al. A decade of experience: Cryptococcus gattii in British Columbia. Mycopathologia. 2012;173:311\u20139.","journal-title":"Mycopathologia"},{"key":"705_CR10","first-page":"865","volume":"59","author":"Centers for Disease Control and Prevention (CDC)","year":"2010","unstructured":"Centers for Disease Control and Prevention (CDC). Emergence of Cryptococcus gattii\u2013Pacific Northwest, 2004\u20132010. MMWR Morb Mortal Wkly Rep. 2010;59:865\u20138.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"705_CR11","doi-asserted-by":"publisher","first-page":"17258","DOI":"10.1073\/pnas.0402981101","volume":"101","author":"SE Kidd","year":"2004","unstructured":"Kidd SE, Hagen F, Tscharke RL, Huynh M, Bartlett KH, Fyfe M, et al. A rare genotype of Cryptococcus gattii caused the cryptococcosis outbreak on Vancouver Island (British Columbia, Canada). Proc Natl Acad Sci U S A. 2004;101:17258\u201363.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"705_CR12","doi-asserted-by":"publisher","first-page":"251","DOI":"10.3201\/eid1602.090900","volume":"16","author":"E Galanis","year":"2010","unstructured":"Galanis E, MacDougall L, Kidd S, Morshed M. Epidemiology of Cryptococcus gattii, British Columbia, Canada, 1999\u20132007. Emerg Infect Dis. 2010;16:251\u20137.","journal-title":"Emerg Infect Dis"},{"key":"705_CR13","doi-asserted-by":"publisher","first-page":"1188","DOI":"10.1093\/cid\/cir723","volume":"53","author":"JR Harris","year":"2011","unstructured":"Harris JR, Lockhart SR, Debess E, Marsden-Haug N, Goldoft M, Wohrle R, et al. Cryptococcus gattii in the United States: clinical aspects of infection with an emerging pathogen. Clin Infect Dis. 2011;53:1188\u201395.","journal-title":"Clin Infect Dis"},{"key":"705_CR14","doi-asserted-by":"publisher","first-page":"e170554","DOI":"10.1590\/0074-02760170554","volume":"113","author":"C Firacative","year":"2018","unstructured":"Firacative C, Lizarazo J, Illnait-Zaragoz\u00ed MT, Casta\u00f1eda E, Latin American Cryptococcal Study Group. The status of cryptococcosis in Latin America. Mem Inst Oswaldo Cruz. 2018;113:e170554.","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"705_CR15","doi-asserted-by":"publisher","first-page":"e0270821","DOI":"10.1128\/mBio.02708-21","volume":"12","author":"D-H Yang","year":"2021","unstructured":"Yang D-H, England MR, Salvator H, Anjum S, Park Y-D, Marr KA, et al. Cryptococcus gattii species complex as an opportunistic pathogen: underlying medical conditions associated with the infection. MBio. 2021;12:e0270821.","journal-title":"MBio"},{"key":"705_CR16","doi-asserted-by":"publisher","first-page":"980","DOI":"10.1128\/CMR.00126-13","volume":"27","author":"SC-A Chen","year":"2014","unstructured":"Chen SC-A, Meyer W, Sorrell TC. Cryptococcus gattii infections. Clin Microbiol Rev. 2014;27:980\u20131024.","journal-title":"Clin Microbiol Rev"},{"key":"705_CR17","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1007\/s11046-021-00577-7","volume":"186","author":"EC Francisco","year":"2021","unstructured":"Francisco EC, de Jong AW, Hagen F. Cryptococcosis and Cryptococcus. Mycopathologia. 2021;186:729\u201331.","journal-title":"Mycopathologia"},{"key":"705_CR18","doi-asserted-by":"publisher","first-page":"683670","DOI":"10.3389\/fcimb.2021.683670","volume":"11","author":"N Hong","year":"2021","unstructured":"Hong N, Chen M, Xu J. Molecular markers reveal epidemiological patterns and evolutionary histories of the human pathogenic Cryptococcus. Front Cell Infect Microbiol. 2021;11:683670.","journal-title":"Front Cell Infect Microbiol"},{"key":"705_CR19","doi-asserted-by":"publisher","first-page":"1648","DOI":"10.1002\/elps.11501601273","volume":"16","author":"W Meyer","year":"1995","unstructured":"Meyer W, Mitchell TG. Polymerase chain reaction fingerprinting in fungi using single primers specific to minisatellites and simple repetitive DNA sequences: strain variation in Cryptococcus neoformans. Electrophoresis. 1995;16:1648\u201356.","journal-title":"Electrophoresis"},{"key":"705_CR20","doi-asserted-by":"publisher","first-page":"5139","DOI":"10.1128\/AAC.00746-10","volume":"54","author":"F Hagen","year":"2010","unstructured":"Hagen F, Illnait-Zaragozi M-T, Bartlett KH, Swinne D, Geertsen E, Klaassen CHW, et al. In vitro antifungal susceptibilities and amplified fragment length polymorphism genotyping of a worldwide collection of 350 clinical, veterinary, and environmental Cryptococcus gattii isolates. Antimicrob Agents Chemother. 2010;54:5139\u201345.","journal-title":"Antimicrob Agents Chemother"},{"key":"705_CR21","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1099\/00221287-147-4-891","volume":"147","author":"T Boekhout","year":"2001","unstructured":"Boekhout T, Theelen B, Diaz M, Fell JW, Hop WCJ, Abeln ECA, et al. Hybrid genotypes in the pathogenic yeast Cryptococcus neoformans. Microbiology (Reading). 2001;147:891\u2013907.","journal-title":"Microbiology (Reading)"},{"key":"705_CR22","doi-asserted-by":"publisher","first-page":"189","DOI":"10.3201\/eid0902.020246","volume":"9","author":"W Meyer","year":"2003","unstructured":"Meyer W, Casta\u00f1eda A, Jackson S, Huynh M, Casta\u00f1eda E, IberoAmerican Cryptococcal Study Group. Molecular typing of IberoAmerican Cryptococcus neoformans isolates. Emerg Infect Dis. 2003;9:189\u201395.","journal-title":"Emerg Infect Dis"},{"key":"705_CR23","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1080\/13693780902953886","volume":"47","author":"W Meyer","year":"2009","unstructured":"Meyer W, Aanensen DM, Boekhout T, Cogliati M, Diaz MR, Esposto MC, et al. Consensus multi-locus sequence typing scheme for Cryptococcus neoformans and Cryptococcus gattii. Med Mycol. 2009;47:561\u201370.","journal-title":"Med Mycol"},{"key":"705_CR24","doi-asserted-by":"publisher","first-page":"e9124","DOI":"10.1371\/journal.pone.0009124","volume":"5","author":"M-T Illnait-Zaragozi","year":"2010","unstructured":"Illnait-Zaragozi M-T, Mart\u00ednez-Mach\u00edn GF, Fern\u00e1ndez-Andreu CM, Boekhout T, Meis JF, Klaassen CHW. Microsatellite typing of clinical and environmental Cryptococcus neoformans var grubii isolates from cuba shows multiple genetic lineages. PLOS ONE. 2010;5:e9124.","journal-title":"PLOS ONE"},{"key":"705_CR25","doi-asserted-by":"publisher","first-page":"e00342","DOI":"10.1128\/mBio.00342-10","volume":"2","author":"CA D\u2019Souza","year":"2011","unstructured":"D\u2019Souza CA, Kronstad JW, Taylor G, Warren R, Yuen M, Hu G, et al. Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts. MBio. 2011;2:e00342-00310.","journal-title":"MBio"},{"key":"705_CR26","first-page":"183","volume":"52","author":"CG Taverna","year":"2020","unstructured":"Taverna CG, Bosco-Borgeat ME, Mazza M, Vivot ME, Davel G, Canteros CE, et al. Frequency and geographical distribution of genotypes and mating types of Cryptococcus neoformans and Cryptococcus gattii species complexes in Argentina. Rev Argent Microbiol. 2020;52:183\u20138.","journal-title":"Rev Argent Microbiol"},{"key":"705_CR27","doi-asserted-by":"publisher","first-page":"282","DOI":"10.3390\/jof7040282","volume":"7","author":"C Firacative","year":"2021","unstructured":"Firacative C, Meyer W, Casta\u00f1eda E. Cryptococcus neoformans and Cryptococcus gattii species complexes in Latin America: a map of molecular types, genotypic diversity, and antifungal susceptibility as reported by the Latin American cryptococcal study group. J Fungi (Basel). 2021;7:282.","journal-title":"J Fungi (Basel)"},{"key":"705_CR28","doi-asserted-by":"publisher","first-page":"e20180419","DOI":"10.1590\/0037-8682-0419-2018","volume":"52","author":"A Berejnoi","year":"2019","unstructured":"Berejnoi A, Taverna CG, Mazza M, Vivot M, Isla G, C\u00f3rdoba S, et al. First case report of cryptococcosis due to Cryptococcus decagattii in a pediatric patient in Argentina. Rev Soc Bras Med Trop. 2019;52:e20180419.","journal-title":"Rev Soc Bras Med Trop"},{"key":"705_CR29","volume-title":"The yeasts a taxonomic study","author":"CP Kurtzman","year":"2011","unstructured":"Kurtzman CP, Fell JW, Boekhout T, Robert V. Methods for isolation, phenotypic characterization and maintenance of yeasts. In: Kurtzman CP, Fell JW, Teun B, editors. The yeasts a taxonomic study. 5th ed. Amsterdam: Elsevier; 2011.","edition":"5"},{"key":"705_CR30","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1093\/mmy\/myy021","volume":"57","author":"CG Taverna","year":"2019","unstructured":"Taverna CG, Mazza M, Bueno NS, Alvarez C, Amigot S, Andreani M, et al. Development and validation of an extended database for yeast identification by MALDI-TOF MS in Argentina. Med Mycol. 2019;57:215\u201325.","journal-title":"Med Mycol"},{"key":"705_CR31","first-page":"95","volume":"41","author":"TA Hall","year":"1999","unstructured":"Hall TA. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95\/98\/NT. Nucl Acids Symp Ser. 1999;41:95\u20138.","journal-title":"Nucl Acids Symp Ser"},{"key":"705_CR32","doi-asserted-by":"publisher","first-page":"1870","DOI":"10.1093\/molbev\/msw054","volume":"33","author":"S Kumar","year":"2016","unstructured":"Kumar S, Stecher G, Tamura K. MEGA7: molecular evolutionary genetics analysis version 7.0 for bigger datasets. Mol Biol Evol. 2016;33:1870\u20134.","journal-title":"Mol Biol Evol"},{"key":"705_CR33","doi-asserted-by":"publisher","first-page":"e0004861","DOI":"10.1371\/journal.pntd.0004861","volume":"10","author":"C Firacative","year":"2016","unstructured":"Firacative C, Roe CC, Malik R, Ferreira-Paim K, Escand\u00f3n P, Sykes JE, et al. MLST and whole-genome-based population analysis of Cryptococcus gattii VGIII links clinical, veterinary and environmental strains, and reveals divergent serotype specific sub-populations and distant ancestors. PLoS Negl Trop Dis. 2016;10:e0004861.","journal-title":"PLoS Negl Trop Dis"},{"key":"705_CR34","doi-asserted-by":"publisher","first-page":"3299","DOI":"10.1093\/molbev\/msx248","volume":"34","author":"J Rozas","year":"2017","unstructured":"Rozas J, Ferrer-Mata A, S\u00e1nchez-DelBarrio JC, Guirao-Rico S, Librado P, Ramos-Onsins SE, et al. DnaSP 6: DNA sequence polymorphism analysis of large data sets. Mol Biol Evol. 2017;34:3299\u2013302.","journal-title":"Mol Biol Evol"},{"key":"705_CR35","doi-asserted-by":"publisher","first-page":"2007","DOI":"10.1128\/JCM.38.5.2007-2009.2000","volume":"38","author":"S Chaturvedi","year":"2000","unstructured":"Chaturvedi S, Rodeghier B, Fan J, McClelland CM, Wickes BL, Chaturvedi V. Direct PCR of Cryptococcus neoformans MATalpha and MATa pheromones to determine mating type, ploidy, and variety: a tool for epidemiological and molecular pathogenesis studies. J Clin Microbiol. 2000;38:2007\u20139.","journal-title":"J Clin Microbiol"},{"key":"705_CR36","doi-asserted-by":"publisher","first-page":"1410","DOI":"10.1128\/EC.4.8.1410-1419.2005","volume":"4","author":"LT Campbell","year":"2005","unstructured":"Campbell LT, Fraser JA, Nichols CB, Dietrich FS, Carter D, Heitman J. Clinical and environmental isolates of Cryptococcus gattii from Australia that retain sexual fecundity. Eukaryot Cell. 2005;4:1410\u20139.","journal-title":"Eukaryot Cell"},{"key":"705_CR37","unstructured":"Arendrup, MC, Meletiadis, J, Mouton, JW, Lagrou, K, Petr Hamal, Guinea, J, et al. EUCAST DEFINITIVE DOCUMENT E.DEF 7.3.2. Method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for yeasts. [Internet], 2020 http:\/\/www.eucast.org."},{"key":"705_CR38","doi-asserted-by":"publisher","first-page":"3107","DOI":"10.1128\/AAC.06252-11","volume":"56","author":"A Espinel-Ingroff","year":"2012","unstructured":"Espinel-Ingroff A, Chowdhary A, Cuenca-Estrella M, Fothergill A, Fuller J, Hagen F, et al. Cryptococcus neoformans-Cryptococcus gattii species complex: an international study of wild-type susceptibility endpoint distributions and epidemiological cutoff values for amphotericin B and flucytosine. Antimicrob Agents Chemother. 2012;56:3107\u201313.","journal-title":"Antimicrob Agents Chemother"},{"key":"705_CR39","doi-asserted-by":"publisher","first-page":"5898","DOI":"10.1128\/AAC.01115-12","volume":"56","author":"A Espinel-Ingroff","year":"2012","unstructured":"Espinel-Ingroff A, Aller AI, Canton E, Casta\u00f1\u00f3n-Olivares LR, Chowdhary A, Cordoba S, et al. Cryptococcus neoformans\u2013Cryptococcus gattii species complex: an international study of wild-type susceptibility endpoint distributions and epidemiological cutoff values for fluconazole, itraconazole, posaconazole, and voriconazole. Antimicrob Agents Chemother. 2012;56:5898\u2013906.","journal-title":"Antimicrob Agents Chemother"},{"key":"705_CR40","doi-asserted-by":"publisher","first-page":"141","DOI":"10.3390\/jof8020141","volume":"8","author":"KMT Astvad","year":"2022","unstructured":"Astvad KMT, Arikan-Akdagli S, Arendrup MC. A pragmatic approach to susceptibility classification of yeasts without EUCAST clinical breakpoints. J Fungi (Basel). 2022;8:141.","journal-title":"J Fungi (Basel)"},{"key":"705_CR41","unstructured":"The European Committee on Antimicrobial Susceptibility Testing. Overview of antifungal ECOFFs and clinical breakpoints for yeasts, moulds and dermatophytes using the EUCAST E.Def 7.3, E.Def 9.4 and E.Def 11.0 procedures. Version 3. [Internet]. 2022. http:\/\/www.eucast.org."},{"key":"705_CR42","doi-asserted-by":"publisher","first-page":"e1004285","DOI":"10.1371\/journal.ppat.1004285","volume":"10","author":"DJ Springer","year":"2014","unstructured":"Springer DJ, Billmyre RB, Filler EE, Voelz K, Pursall R, Mieczkowski PA, et al. Cryptococcus gattii VGIII isolates causing infections in HIV\/AIDS patients in Southern California: identification of the local environmental source as arboreal. PLoS Pathog. 2014;10:e1004285.","journal-title":"PLoS Pathog"},{"key":"705_CR43","doi-asserted-by":"publisher","first-page":"e3272","DOI":"10.1371\/journal.pntd.0003272","volume":"8","author":"J Lizarazo","year":"2014","unstructured":"Lizarazo J, Escand\u00f3n P, Agudelo CI, Firacative C, Meyer W, Casta\u00f1eda E. Retrospective study of the epidemiology and clinical manifestations of Cryptococcus gattii infections in Colombia from 1997\u20132011. PLoS Negl Trop Dis. 2014;8:e3272.","journal-title":"PLoS Negl Trop Dis"},{"key":"705_CR44","doi-asserted-by":"publisher","first-page":"e37566","DOI":"10.1371\/journal.pone.0037566","volume":"7","author":"C Firacative","year":"2012","unstructured":"Firacative C, Trilles L, Meyer W. MALDITOF MS enables the rapid identification of the major molecular types within the Cryptococcus neoformans\/C. gattii species complex. PLoS ONE. 2012;7:e37566.","journal-title":"PLoS ONE"},{"key":"705_CR45","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1080\/13693780802227290","volume":"47","author":"N Refojo","year":"2009","unstructured":"Refojo N, Perrotta D, Brudny M, Abrantes R, Hevia AI, Davel G. Isolation of Cryptococcus neoformans and Cryptococcus gattii from trunk hollows of living trees in Buenos Aires City. Argent Med Mycol. 2009;47:177\u201384.","journal-title":"Argent Med Mycol"},{"key":"705_CR46","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1111\/myc.12084","volume":"56","author":"M Mazza","year":"2013","unstructured":"Mazza M, Refojo N, Bosco-Borgeat ME, Taverna CG, Trovero AC, Rog\u00e9 A, et al. Cryptococcus gattii in urban trees from cities in North-Eastern Argentina. Mycoses. 2013;56:646\u201350.","journal-title":"Mycoses"},{"key":"705_CR47","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1016\/j.riam.2013.06.005","volume":"31","author":"ME Cattana","year":"2014","unstructured":"Cattana ME, de Sosa L\u00c1 M, Fern\u00e1ndez M, Rojas F, Mangiaterra M, Giusiano G. Native trees of the Northeast Argentine: natural hosts of the Cryptococcus neoformans\u2013Cryptococcus gattii species complex. Rev Iberoam Micol. 2014;31:188\u201392.","journal-title":"Rev Iberoam Micol"},{"key":"705_CR48","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1128\/JCM.41.2.703-711.2003","volume":"41","author":"CL Halliday","year":"2003","unstructured":"Halliday CL, Carter DA. Clonal reproduction and limited dispersal in an environmental population of Cryptococcus neoformans var. gattii isolates from Australia. J Clin Microbiol. 2003;41:703\u201311.","journal-title":"J Clin Microbiol."},{"key":"705_CR49","doi-asserted-by":"publisher","first-page":"e16936","DOI":"10.1371\/journal.pone.0016936","volume":"6","author":"F Carriconde","year":"2011","unstructured":"Carriconde F, Gilgado F, Arthur I, Ellis D, Malik R, van de Wiele N, et al. Clonality and \u03b1-a recombination in the Australian Cryptococcus gattii VGII population\u2013an emerging outbreak in Australia. PLoS ONE. 2011;6:e16936.","journal-title":"PLoS ONE"},{"key":"705_CR50","doi-asserted-by":"publisher","first-page":"e74737","DOI":"10.1371\/journal.pone.0074737","volume":"8","author":"SR Lockhart","year":"2013","unstructured":"Lockhart SR, Iqbal N, Harris JR, Grossman NT, DeBess E, Wohrle R, et al. Cryptococcus gattii in the United States: genotypic diversity of human and veterinary isolates. PLoS ONE. 2013;8:e74737.","journal-title":"PLoS ONE"},{"key":"705_CR51","doi-asserted-by":"publisher","first-page":"89","DOI":"10.2147\/IDR.S57686","volume":"8","author":"A Espinel-Ingroff","year":"2015","unstructured":"Espinel-Ingroff A, Kidd SE. Current trends in the prevalence of Cryptococcus gattii in the United States and Canada. Infect Drug Resist. 2015;8:89\u201397.","journal-title":"Infect Drug Resist"},{"key":"705_CR52","doi-asserted-by":"publisher","first-page":"132","DOI":"10.3389\/fmicb.2018.00132","volume":"9","author":"VA Barcellos","year":"2018","unstructured":"Barcellos VA, Martins LMS, Fontes ACL, Reuwsaat JCV, Squizani ED, de Sousa Ara\u00fajo GR, et al. Genotypic and phenotypic diversity of Cryptococcus gattii VGII clinical isolates and its impact on virulence. Front Microbiol. 2018;9:132.","journal-title":"Front Microbiol"},{"key":"705_CR53","doi-asserted-by":"publisher","first-page":"1126","DOI":"10.1093\/mmy\/myaa019","volume":"58","author":"AM Vilas-B\u00f4as","year":"2020","unstructured":"Vilas-B\u00f4as AM, Andrade-Silva LE, Ferreira-Paim K, Mora DJ, Ferreira TB, de Santos DA, et al. High genetic variability of clinical and environmental Cryptococcus gattii isolates from Brazil. Med Mycol. 2020;58:1126\u201337.","journal-title":"Med Mycol."},{"key":"705_CR54","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/s11046-018-0313-2","volume":"184","author":"FH Maruyama","year":"2019","unstructured":"Maruyama FH, de Paula DAJ, de Menezes I, G, Favalessa OC, Hahn RC, de Almeida A do BPF, et al. Genetic diversity of the Cryptococcus gattii species complex in Mato Grosso State, Brazil. Mycopathologia. 2019;184:45\u201351.","journal-title":"Mycopathologia"},{"key":"705_CR55","doi-asserted-by":"publisher","first-page":"e71148","DOI":"10.1371\/journal.pone.0071148","volume":"8","author":"F Hagen","year":"2013","unstructured":"Hagen F, Ceresini PC, Polacheck I, Ma H, van Nieuwerburgh F, Gabald\u00f3n T, et al. Ancient dispersal of the human fungal pathogen Cryptococcus gattii from the Amazon rainforest. PLoS ONE. 2013;8:e71148.","journal-title":"PLoS ONE"},{"key":"705_CR56","doi-asserted-by":"publisher","first-page":"e0004885","DOI":"10.1371\/journal.pntd.0004885","volume":"10","author":"ACP Souto","year":"2016","unstructured":"Souto ACP, Bonfietti LX, Ferreira-Paim K, Trilles L, Martins M, Ribeiro-Alves M, et al. Population genetic analysis reveals a high genetic diversity in the Brazilian Cryptococcus gattii VGII population and shifts the global origin from the Amazon rainforest to the semi-arid desert in the Northeast of Brazil. PLoS Negl Trop Dis. 2016;10:e0004885.","journal-title":"PLoS Negl Trop Dis"},{"key":"705_CR57","doi-asserted-by":"publisher","first-page":"e01464","DOI":"10.1128\/mBio.01464-14","volume":"5","author":"DM Engelthaler","year":"2014","unstructured":"Engelthaler DM, Hicks ND, Gillece JD, Roe CC, Schupp JM, Driebe EM, et al. Cryptococcus gattii in North American Pacific Northwest: whole-population genome analysis provides insights into species evolution and dispersal. MBio. 2014;5:e01464-01414.","journal-title":"MBio"},{"key":"705_CR58","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1093\/mmy\/myab041","volume":"59","author":"C Firacative","year":"2021","unstructured":"Firacative C, Escand\u00f3n P. Antifungal susceptibility of clinical Cryptococcus gattii isolates from Colombia varies among molecular types. Med Mycol. 2021;59:1122\u20135.","journal-title":"Med Mycol"},{"key":"705_CR59","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1093\/mmy\/myy161","volume":"57","author":"G-HA Lee","year":"2019","unstructured":"Lee G-HA, Arthur I, Merritt A, Leung M. Molecular types of Cryptococcus neoformans and Cryptococcus gattii in Western Australia and correlation with antifungal susceptibility. Med Mycol. 2019;57:1004\u201310.","journal-title":"Med Mycol"},{"key":"705_CR60","unstructured":"M59 epidemiological cutoff values for antifungal susceptibility testing, 3rd Edition. Clinical and Laboratory Standards Institute, Wayne, 2022"}],"container-title":["Mycopathologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11046-022-00705-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11046-022-00705-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11046-022-00705-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T22:06:35Z","timestamp":1683756395000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11046-022-00705-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,7]]},"references-count":60,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["705"],"URL":"https:\/\/doi.org\/10.1007\/s11046-022-00705-x","relation":{},"ISSN":["0301-486X","1573-0832"],"issn-type":[{"type":"print","value":"0301-486X"},{"type":"electronic","value":"1573-0832"}],"subject":[],"published":{"date-parts":[[2023,1,7]]},"assertion":[{"value":"19 July 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 December 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 January 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This is an observational study. No ethical approval is required.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}