{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:50:18Z","timestamp":1790704218849,"version":"4.1.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T00:00:00Z","timestamp":1687910400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T00:00:00Z","timestamp":1687910400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mycopathologia"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1007\/s11046-023-00757-7","type":"journal-article","created":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T17:02:01Z","timestamp":1687971721000},"page":"353-360","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The Epidemiology and Clinical Characteristics of Fungemia in a Tertiary Hospital in Southern China: A 6-Year Retrospective Study"],"prefix":"10.1007","volume":"188","author":[{"given":"Meini","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongmei","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianmin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongyan","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanqing","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaobo","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cunwei","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,6,28]]},"reference":[{"issue":"4","key":"757_CR1","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1179\/joc.2001.13.4.429","volume":"13","author":"G Kovacicova","year":"2001","unstructured":"Kovacicova G, Lovaszova M, Hanzen J, Roidova A, Mateicka F, Lesay M, Kr\u010dm\u00e9ry V. Persistent fungemia-Risk factors And outcome in 40 episodes. J Chemother. 2001;13(4):429\u201333.","journal-title":"J Chemother"},{"issue":"1","key":"757_CR2","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1186\/s13054-020-2766-1","volume":"24","author":"J Poissy","year":"2020","unstructured":"Poissy J, Damonti L, Bignon A, Khanna N, Von Kietzell M, Boggian K, Neofytos D, Vuotto F, Coiteux V, Artru F, Zimmerli S. Risk factors for candidemia: a prospective matched case-control study. Crit Care. 2020;24(1):109.","journal-title":"Crit Care"},{"issue":"5","key":"757_CR3","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1007\/s11046-011-9444-4","volume":"172","author":"CJ Seneviratne","year":"2011","unstructured":"Seneviratne CJ, et al. Antifungal susceptibility and virulence attributes of bloodstream isolates of Candida from Hong Kong and Finland. Mycopathologia. 2011;172(5):389\u201395.","journal-title":"Mycopathologia"},{"issue":"9","key":"757_CR4","doi-asserted-by":"publisher","first-page":"myac071","DOI":"10.1093\/mmy\/myac071","volume":"60","author":"T Kajihara","year":"2022","unstructured":"Kajihara T, et al. Distribution, trends, and antifungal susceptibility of Candida species causing candidemia in Japan, 2010\u20132019: a retrospective observational study based on national surveillance data. Med Mycol. 2022;60(9):myac071.","journal-title":"Med Mycol"},{"issue":"3","key":"757_CR5","doi-asserted-by":"publisher","first-page":"e0092022","DOI":"10.1128\/mbio.00920-22","volume":"13","author":"S Bretagne","year":"2022","unstructured":"Bretagne S, et al. Active surveillance program to increase awareness on invasive fungal diseases: the French RESSIF Network (2012 to 2018). mBio. 2022;13(3):e0092022.","journal-title":"mBio"},{"key":"757_CR6","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1590\/1806-9282.62.04.315","volume":"62","author":"LL Castro","year":"2016","unstructured":"Castro LL, Sch\u00fctze M, B\u00fccker DH, Vasconcellos LDS. Prevalence of fungemia in a tertiary hospital: analysis of the last decade. Rev Assoc M\u00e9d Bras. 2016;62:315\u20139.","journal-title":"Rev Assoc M\u00e9d Bras"},{"issue":"6","key":"757_CR7","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1093\/mmy\/myw017","volume":"54","author":"VA Gaona-Flores","year":"2016","unstructured":"Gaona-Flores VA, Campos-Navarro LA, Cervantes-Tovar RM, Alcal\u00e1-Mart\u00ednez E. The epidemiology of fungemia in an infectious diseases hospital in Mexico city: a 10-year retrospective review. Med Mycol. 2016;54(6):600\u20134.","journal-title":"Med Mycol."},{"issue":"4","key":"757_CR8","doi-asserted-by":"publisher","first-page":"e01827","DOI":"10.1128\/AAC.01827-20","volume":"65","author":"J D\u00edaz-Garc\u00eda","year":"2021","unstructured":"D\u00edaz-Garc\u00eda J, et al. Monitoring the epidemiology and antifungal resistance of yeasts causing fungemia in a tertiary care hospital in Madrid, Spain: any relevant changes in the last 13 years? Antimicrob Agents Chemother. 2021;65(4):e01827.","journal-title":"Antimicrob Agents Chemother"},{"issue":"2","key":"757_CR9","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1111\/myc.12852","volume":"62","author":"SY Lin","year":"2019","unstructured":"Lin SY, Lu PL, Tan BH, Chakrabarti A, Wu UI, Yang JH, Patel AK, Li RY, Watcharananan SP, Liu Z, Chindamporn A. The epidemiology of non-Candida yeast isolated from blood: the Asia surveillance study. Mycoses. 2019;62(2):112\u201320.","journal-title":"Mycoses"},{"issue":"2","key":"757_CR10","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1093\/mmy\/myw055","volume":"55","author":"M Fern\u00e1ndez-Ruiz","year":"2017","unstructured":"Fern\u00e1ndez-Ruiz M, Guinea J, Puig-Asensio M, Zaragoza \u00d3, Almirante B, Cuenca-Estrella M, Aguado JM, CANDIPOP Project; GEIH-GEMICOMED (SEIMC) and REIPI. Fungemia due to rare opportunistic yeasts: data from a population-based surveillance in Spain. Med Mycol. 2017;55(2):125\u201336.","journal-title":"Med Mycol"},{"issue":"3","key":"757_CR11","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1093\/jac\/dkx436","volume":"73","author":"A \u00c1lvarez-Ur\u00eda","year":"2018","unstructured":"\u00c1lvarez-Ur\u00eda A, Mu\u00f1oz P, Vena A, Guinea J, Marcos-Zambrano LJ, Escribano P, S\u00e1nchez-Carrillo C, Bouza E. Fungaemia caused by rare yeasts: incidence, clinical characteristics and outcome over 10 years. J Antimicrob Chemother. 2018;73(3):823\u20135.","journal-title":"J Antimicrob Chemother"},{"key":"757_CR12","doi-asserted-by":"publisher","first-page":"e169","DOI":"10.1017\/S0950268820001624","volume":"148","author":"H Li","year":"2020","unstructured":"Li H, et al. Epidemiological study of Trichosporon asahii infections over the past 23 years. Epidemiol Infect. 2020;148:e169.","journal-title":"Epidemiol Infect"},{"issue":"2","key":"757_CR13","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1111\/myc.12852","volume":"62","author":"SY Lin","year":"2019","unstructured":"Lin SY, et al. The epidemiology of non-Candida yeast isolated from blood: the Asia surveillance study. Mycoses. 2019;62(2):112\u201320.","journal-title":"Mycoses"},{"issue":"1","key":"757_CR14","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1186\/s12879-022-07848-8","volume":"22","author":"D Meyahnwi","year":"2022","unstructured":"Meyahnwi D, Siraw BB, Reingold A. Epidemiologic features, clinical characteristics, and predictors of mortality in patients with candidemia in Alameda County, California; a 2017\u20132020 retrospective analysis. BMC Infect Dis. 2022;22(1):843.","journal-title":"BMC Infect Dis"},{"issue":"3","key":"757_CR15","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1111\/myc.13211","volume":"64","author":"CL Keighley","year":"2021","unstructured":"Keighley CL, et al. Risk factors for candidaemia: A prospective multi-centre case-control study. Mycoses. 2021;64(3):257\u201363.","journal-title":"Mycoses"},{"issue":"6","key":"757_CR16","doi-asserted-by":"publisher","first-page":"597","DOI":"10.7883\/yoken.JJID.2022.181","volume":"75","author":"S Aydin","year":"2022","unstructured":"Aydin S, et al. Epidemiology of nosocomial candidemia, mortality, and antifungal resistance: 7-year experience in Turkey. Jpn J Infect Dis. 2022;75(6):597\u2013603.","journal-title":"Jpn J Infect Dis"},{"issue":"2","key":"757_CR17","doi-asserted-by":"publisher","first-page":"e0045321","DOI":"10.1128\/Spectrum.00453-21","volume":"9","author":"D Y\u0131lmaz-Ciftdo\u011fan","year":"2021","unstructured":"Y\u0131lmaz-Ciftdo\u011fan D, et al. Epidemiology of Candidemia in children over 7 years in a medical center in Turkey. Microbiol Spectr. 2021;9(2):e0045321.","journal-title":"Microbiol Spectr"},{"key":"757_CR18","doi-asserted-by":"publisher","first-page":"e277","DOI":"10.1017\/S0950268819001638","volume":"147","author":"W Zhang","year":"2019","unstructured":"Zhang W, et al. Epidemiology, risk factors and outcomes of Candida albicans vs. non-albicans candidaemia in adult patients in Northeast China. Epidemiol Infect. 2019;147:e277.","journal-title":"Epidemiol Infect"},{"issue":"1","key":"757_CR19","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1186\/s12879-018-3100-2","volume":"18","author":"JF Hsu","year":"2018","unstructured":"Hsu JF, et al. Comparison of the incidence, clinical features and outcomes of invasive candidiasis in children and neonates. BMC Infect Dis. 2018;18(1):194.","journal-title":"BMC Infect Dis"},{"issue":"1","key":"757_CR20","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1186\/s12879-016-2042-9","volume":"16","author":"J Chen","year":"2016","unstructured":"Chen J, et al. Epidemiology of and risk factors for neonatal candidemia at a tertiary care hospital in western China. BMC Infect Dis. 2016;16(1):700.","journal-title":"BMC Infect Dis"},{"issue":"3","key":"757_CR21","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1159\/000092189","volume":"15","author":"Z Zhiyong","year":"2006","unstructured":"Zhiyong Z, Mei K, Yanbin L. Disseminated Penicillium marneffei infection with fungemia and endobronchial disease in an AIDS patient in China. Med Princ Pract. 2006;15(3):235\u20137.","journal-title":"Med Princ Pract"},{"issue":"5\u20136","key":"757_CR22","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1007\/s11046-014-9855-0","volume":"179","author":"D Dong","year":"2015","unstructured":"Dong D, et al. Clinical and microbiological investigation of fungemia from four hospitals in China. Mycopathologia. 2015;179(5\u20136):407\u201314.","journal-title":"Mycopathologia"},{"issue":"1","key":"757_CR23","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1007\/s15010-021-01649-y","volume":"50","author":"J Cui","year":"2022","unstructured":"Cui J, et al. The proportion, species distribution and dynamic trends of bloodstream infection cases in a tertiary hospital in China, 2010\u20132019. Infection. 2022;50(1):121\u201330.","journal-title":"Infection"},{"issue":"12","key":"757_CR24","first-page":"952","volume":"51","author":"L Zhang","year":"2012","unstructured":"Zhang L, et al. The clinical characteristics of 70 cases of fungemia. Zhonghua Nei Ke Za Zhi. 2012;51(12):952\u20136.","journal-title":"Zhonghua Nei Ke Za Zhi"},{"issue":"4","key":"757_CR25","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1007\/s11046-018-0258-5","volume":"183","author":"S Lin","year":"2018","unstructured":"Lin S, et al. Candidemia in adults at a tertiary hospital in China: clinical characteristics, species distribution, resistance, and outcomes. Mycopathologia. 2018;183(4):679\u201389.","journal-title":"Mycopathologia"},{"key":"757_CR26","doi-asserted-by":"publisher","first-page":"2529171","DOI":"10.1155\/2021\/2529171","volume":"2021","author":"Y Bai","year":"2021","unstructured":"Bai Y, et al. Epidemiological characteristics and drug resistance of fungemia in general hospitals from 2010 to 2019. Biomed Res Int. 2021;2021:2529171.","journal-title":"Biomed Res Int"},{"issue":"5","key":"757_CR27","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1016\/j.cmi.2014.12.014","volume":"21","author":"YF Wang","year":"2015","unstructured":"Wang YF, et al. Serological surveillance for Penicillium marneffei infection in HIV-infected patients during 2004\u20132011 in Guangzhou, China. Clin Microbiol Infect. 2015;21(5):484\u20139.","journal-title":"Clin Microbiol Infect"},{"issue":"11","key":"757_CR28","doi-asserted-by":"publisher","first-page":"1387","DOI":"10.1111\/myc.13297","volume":"64","author":"H Kaur","year":"2021","unstructured":"Kaur H, et al. Fungaemia due to rare yeasts in paediatric intensive care units: A prospective study. Mycoses. 2021;64(11):1387\u201395.","journal-title":"Mycoses"},{"key":"757_CR29","volume-title":"Internal medicine","author":"J Ge","year":"2017","unstructured":"Ge J. Internal medicine. Beijing: People\u2019s Medical Publishing House; 2017."},{"key":"757_CR30","volume-title":"Infectious diseases","author":"L Li","year":"2017","unstructured":"Li L. Infectious diseases. Beijing: People\u2019s Medical Publishing House; 2017."},{"key":"757_CR31","volume-title":"Neurology","author":"J Jia","year":"2017","unstructured":"Jia J. Neurology. Beijing: People\u2019s Medical Publishing House; 2017."},{"issue":"4","key":"757_CR32","doi-asserted-by":"publisher","first-page":"281","DOI":"10.5847\/wjem.j.1920-8642.2021.04.005","volume":"12","author":"HY Wei","year":"2021","unstructured":"Wei HY, et al. Clinical characteristics and risk factors of Talaromyces marneffei infection in human immunodeficiency virus-negative patients: A retrospective observational study. World J Emerg Med. 2021;12(4):281\u20136.","journal-title":"World J Emerg Med"},{"key":"757_CR33","doi-asserted-by":"publisher","first-page":"701913","DOI":"10.3389\/fcimb.2021.701913","volume":"11","author":"ZT Li","year":"2021","unstructured":"Li ZT, et al. Serum Sphingolipids aiding the diagnosis of adult HIV-negative patients with Talaromyces marneffei infection. Front Cell Infect Microbiol. 2021;11:701913.","journal-title":"Front Cell Infect Microbiol"},{"issue":"3","key":"757_CR34","volume":"5","author":"JF Chan","year":"2016","unstructured":"Chan JF, et al. Talaromyces (Penicillium) marneffei infection in non-HIV-infected patients. Emerg Microbes Infect. 2016;5(3): e19.","journal-title":"Emerg Microbes Infect"},{"issue":"1\u20132","key":"757_CR35","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1007\/s11046-012-9577-0","volume":"175","author":"Y Hu","year":"2013","unstructured":"Hu Y, et al. Penicillium marneffei infection: an emerging disease in mainland China. Mycopathologia. 2013;175(1\u20132):57\u201367.","journal-title":"Mycopathologia"},{"issue":"5","key":"757_CR36","doi-asserted-by":"publisher","first-page":"E59","DOI":"10.1016\/j.ajic.2015.11.028","volume":"44","author":"XY Gong","year":"2016","unstructured":"Gong XY, et al. Invasive candidiasis in intensive care units in China: risk factors and prognoses of Candida albicans and non-albicans Candida infections. Am J Infect Control. 2016;44(5):E59\u201363.","journal-title":"Am J Infect Control"},{"issue":"12","key":"757_CR37","doi-asserted-by":"publisher","first-page":"1695","DOI":"10.1086\/599039","volume":"48","author":"DL Horn","year":"2009","unstructured":"Horn DL, et al. Epidemiology and outcomes of candidemia in 2019 patients: data from the prospective antifungal therapy alliance registry. Clin Infect Dis. 2009;48(12):1695\u2013703.","journal-title":"Clin Infect Dis"},{"issue":"4","key":"757_CR38","first-page":"988","volume":"72","author":"MI Xisto","year":"2017","unstructured":"Xisto MI, et al. Pan-azole-resistant Candida tropicalis carrying homozygous erg11 mutations at position K143R: a new emerging superbug? J Antimicrob Chemother. 2017;72(4):988\u201392.","journal-title":"J Antimicrob Chemother"},{"issue":"Pt 8","key":"757_CR39","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1099\/jmm.0.013227-0","volume":"59","author":"RJ Kothavade","year":"2010","unstructured":"Kothavade RJ, et al. Candida tropicalis: its prevalence, pathogenicity and increasing resistance to fluconazole. J Med Microbiol. 2010;59(Pt 8):873\u201380.","journal-title":"J Med Microbiol"},{"issue":"5","key":"757_CR40","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1016\/j.jmii.2010.08.011","volume":"44","author":"YC Lee","year":"2011","unstructured":"Lee YC, et al. Comparisons of clinical features and mortality of cryptococcal meningitis between patients with and without human immunodeficiency virus infection. J Microbiol Immunol Infect. 2011;44(5):338\u201345.","journal-title":"J Microbiol Immunol Infect"},{"issue":"1","key":"757_CR41","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1128\/JCM.01811-10","volume":"49","author":"MC Arendrup","year":"2011","unstructured":"Arendrup MC, et al. National surveillance of fungemia in Denmark (2004 to 2009). J Clin Microbiol. 2011;49(1):325\u201334.","journal-title":"J Clin Microbiol"},{"issue":"4","key":"757_CR42","doi-asserted-by":"publisher","first-page":"e01564","DOI":"10.1128\/JCM.01564-17","volume":"56","author":"KMT Astvad","year":"2018","unstructured":"Astvad KMT, et al. Update from a 12-Year Nationwide fungemia surveillance: increasing intrinsic and acquired resistance causes concern. J Clin Microbiol. 2018;56(4):e01564.","journal-title":"J Clin Microbiol"}],"container-title":["Mycopathologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11046-023-00757-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11046-023-00757-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11046-023-00757-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,29]],"date-time":"2023-07-29T05:20:15Z","timestamp":1690608015000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11046-023-00757-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,28]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["757"],"URL":"https:\/\/doi.org\/10.1007\/s11046-023-00757-7","relation":{},"ISSN":["0301-486X","1573-0832"],"issn-type":[{"value":"0301-486X","type":"print"},{"value":"1573-0832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,28]]},"assertion":[{"value":"27 December 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 May 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 June 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}