{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T16:59:44Z","timestamp":1788886784364,"version":"build-2803163510"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2006,3,23]],"date-time":"2006-03-23T00:00:00Z","timestamp":1143072000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurooncol"],"published-print":{"date-parts":[[2006,6]]},"DOI":"10.1007\/s11060-005-9076-y","type":"journal-article","created":{"date-parts":[[2006,3,22]],"date-time":"2006-03-22T05:19:20Z","timestamp":1143004760000},"page":"113-121","source":"Crossref","is-referenced-by-count":42,"title":["A genetic strategy to overcome the senescence of primary meningioma cell cultures"],"prefix":"10.1007","volume":"78","author":[{"given":"Gilson S.","family":"Baia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison L.","family":"Slocum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanette D.","family":"Hyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjan","family":"Misra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nouzhan","family":"Sehati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott R.","family":"VandenBerg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burt G.","family":"Feuerstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis F.","family":"Deen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael W.","family":"McDermott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Lal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,3,23]]},"reference":[{"key":"9076_CR1","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1097\/00019052-200412000-00008","volume":"17","author":"E Lusis","year":"2004","unstructured":"Lusis E, Gutmann DH (2004) Meningioma: an updateCurr Opin Neurol 17:687\u2013692","journal-title":"Curr Opin Neurol"},{"key":"9076_CR2","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1158\/0008-5472.CAN-04-0786","volume":"65","author":"VK Puduvalli","year":"2005","unstructured":"Puduvalli VK, Li JT, Chen L, McCutcheon IE (2005) Induction of apoptosis in primary meningioma cultures by fenretinideCancer Res 65:1547\u20131553","journal-title":"Cancer Res"},{"key":"9076_CR3","doi-asserted-by":"crossref","first-page":"441","DOI":"10.3171\/jns.2002.97.2.0441","volume":"97","author":"CM Dirven","year":"2002","unstructured":"Dirven CM, Grill J, Lamfers ML, Van der Valk P, Leonhart AM, Van Beusechem VW, Haisma HJ, Pinedo HM, Curiel DT, Vandertop WP, Gerritsen WR (2002) Gene therapy for meningioma: improved gene delivery with targeted adenovirusesJ Neurosurg 97:441\u2013449","journal-title":"J Neurosurg"},{"key":"9076_CR4","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3171\/jns.1999.91.1.0085","volume":"91","author":"K Ikeda","year":"1999","unstructured":"Ikeda K, Saeki Y, Gonzalez-Agosti C, Ramesh V, Chiocca EA (1999) Inhibition of NF2-negative and NF2-positive primary human meningioma cell proliferation by overexpression of merlin due to vector-mediated gene transferJ Neurosurg 91:85\u201392","journal-title":"J Neurosurg"},{"key":"9076_CR5","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1097\/00006123-199903000-00080","volume":"44","author":"J Shu","year":"1999","unstructured":"Shu J, Lee JH, Harwalkar JA, Oh-Siskovic S, Stacey DW, Golubic M (1999) Adenovirus-mediated gene transfer of dominant negative Ha-Ras inhibits proliferation of primary meningioma cellsNeurosurgery 44:579\u2013587","journal-title":"Neurosurgery"},{"key":"9076_CR6","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1227\/00006123-199009000-00008","volume":"27","author":"WH Lee","year":"1990","unstructured":"Lee WH, (1990) Characterization of a newly established malignant meningioma cell line of the human brain: IOMM-LeeNeurosurgery 27:389\u2013395","journal-title":"Neurosurgery"},{"key":"9076_CR7","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1002\/1097-0142(19891201)64:11<2243::AID-CNCR2820641110>3.0.CO;2-S","volume":"64","author":"K Tanaka","year":"1989","unstructured":"Tanaka K, Sato C, Maeda Y, Koike M, Matsutani M, Yamada K, Miyaki M (1989) Establishment of a human malignant meningioma cell line with amplified c-myc oncogeneCancer 64:2243\u20132249","journal-title":"Cancer"},{"key":"9076_CR8","first-page":"6090","volume":"54","author":"M Sasaki","year":"1994","unstructured":"Sasaki M, Honda T, Yamada H, Wake N, Barrett JC, Oshimura M (1994) Evidence for multiple pathways to cellular senescenceCancer Res 54:6090\u20136093","journal-title":"Cancer Res"},{"key":"9076_CR9","doi-asserted-by":"crossref","first-page":"4240","DOI":"10.1002\/j.1460-2075.1995.tb00098.x","volume":"14","author":"TM Bryan","year":"1995","unstructured":"Bryan TM, Englezou A, Gupta J, Bacchetti S, Reddel RR (1995) Telomere elongation in immortal human cells without detectable telomerase activityEMBO J 14:4240\u20134248","journal-title":"EMBO J"},{"key":"9076_CR10","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1038\/nm1197-1271","volume":"3","author":"TM Bryan","year":"1997","unstructured":"Bryan TM, Englezou A, Dalla-Pozza L, Dunham MA, Reddel RR (1997) Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell linesNat Med 3:1271\u20131274","journal-title":"Nat Med"},{"key":"9076_CR11","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.1016\/S0962-8924(01)02151-1","volume":"11","author":"J Campisi","year":"2001","unstructured":"Campisi J, (2001) Cellular senescence as a tumor-suppressor mechanism. Trends Cell Biol 11:S27\u2013S31","journal-title":"Trends Cell Biol"},{"key":"9076_CR12","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/23962","volume":"396","author":"T Kiyono","year":"1998","unstructured":"Kiyono T, Foster SA, Koop JI, McDougall JK, Galloway DA, Klingelhutz AJ (1998) Both Rb\/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cellsNature 396:84\u201388","journal-title":"Nature"},{"key":"9076_CR13","doi-asserted-by":"crossref","first-page":"636","DOI":"10.2307\/3579284","volume":"145","author":"N Gupta","year":"1996","unstructured":"Gupta N, Lamborn K, Deen DF (1996) A statistical approach for analyzing clonogenic survival dataRadiat Res 145:636\u2013640","journal-title":"Radiat Res"},{"key":"9076_CR14","doi-asserted-by":"crossref","first-page":"5070","DOI":"10.1158\/0008-5472.CAN-05-0240","volume":"65","author":"IC Cuevas","year":"2005","unstructured":"Cuevas IC, Slocum AL, Jun P, Costello JF, Bollen AW, Riggins GJ, McDermott MW, Lal A (2005) Meningioma transcript profiles reveal deregulated notch signaling pathwayCancer Res 65:5070\u20135075","journal-title":"Cancer Res"},{"key":"9076_CR15","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/ng754","volume":"29","author":"AM Snijders","year":"2001","unstructured":"Snijders AM, Nowak N, Segraves R, Blackwood S, Brown N, Conroy J, Hamilton G, Hindle AK, Huey B, Kimura K, Law S, Myambo K, Palmer J, Ylstra B, Yue JP, Gray JW, Jain AN, Pinkel D, Albertson DG (2001) Assembly of microarrays for genome-wide measurement of DNA copy numberNat Genet 29:263\u2013264","journal-title":"Nat Genet"},{"key":"9076_CR16","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1101\/gr.210902","volume":"12","author":"AN Jain","year":"2002","unstructured":"Jain AN, Tokuyasu TA, Snijders AM, Segraves R, Albertson DG, Pinkel D (2002) Fully automatic quantification of microarray image dataGenome Res 12:325\u2013332","journal-title":"Genome Res"},{"key":"9076_CR17","first-page":"239","volume":"22","author":"PM Howley","year":"1991","unstructured":"Howley PM, Munger K, Romanczuk H, Scheffner M, Huibregtse JM (1991) Cellular targets of the oncoproteins encoded by the cancer associated human papillomavirusesPrincess Takamatsu Symp 22:239\u2013248","journal-title":"Princess Takamatsu Symp"},{"key":"9076_CR18","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/S0002-9440(10)61737-3","volume":"159","author":"J Bostrom","year":"2001","unstructured":"Bostrom J, Meyer-Puttlitz B, Wolter M, Blaschke B, Weber RG, Lichter P, Ichimura K, Collins VP, Reifenberger G (2001) Alterations of the tumor suppressor genes CDKN2A (p16(INK4a)), p14(ARF), CDKN2B (p15(INK4b)), and CDKN2C (p18(INK4c)) in atypical and anaplastic meningiomasAm J Pathol 159:661\u2013669","journal-title":"Am J Pathol"},{"key":"9076_CR19","first-page":"7594","volume":"61","author":"AL Ducrest","year":"2001","unstructured":"Ducrest AL, Amacker M, Mathieu YD, Cuthbert AP, Trott DA, Newbold RF, Nabholz M, Lingner J (2001) Regulation of human telomerase activity: repression by normal chromosome 3 abolishes nuclear telomerase reverse transcriptase transcripts but does not affect c-Myc activityCancer Res 61:7594\u20137602","journal-title":"Cancer Res"},{"key":"9076_CR20","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/(SICI)1521-1878(199801)20:1<79::AID-BIES11>3.0.CO;2-5","volume":"20","author":"RM Evans","year":"1998","unstructured":"Evans RM (1998) Vimentin: the conundrum of the intermediate filament gene familyBioessays 20:79\u201386","journal-title":"Bioessays"},{"key":"9076_CR21","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0968-4328(98)00015-8","volume":"29","author":"ID Burdett","year":"1998","unstructured":"Burdett ID (1998) Aspects of the structure and assembly of desmosomesMicron 29:309\u2013328","journal-title":"Micron"},{"key":"9076_CR22","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/s00401-003-0736-8","volume":"106","author":"K Akat","year":"2003","unstructured":"Akat K, Mennel HD, Kremer P, Gassler N, Bleck CK, Kartenbeck J (2003) Molecular characterization of desmosomes in meningiomas and arachnoidal tissueActa Neuropathol (Berl) 106:337\u2013347","journal-title":"Acta Neuropathol (Berl)"},{"key":"9076_CR23","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1038\/ng771","volume":"29","author":"G Hodgson","year":"2001","unstructured":"Hodgson G, Hager JH, Volik S, Hariono S, Wernick M, Moore D, Nowak N, Albertson DG, Pinkel D, Collins C, Hanahan D, Gray JW (2001) Genome scanning with array CGH delineates regional alterations in mouse islet carcinomasNat Genet 29:459\u2013464","journal-title":"Nat Genet"},{"key":"9076_CR24","doi-asserted-by":"crossref","first-page":"2907","DOI":"10.1158\/1078-0432.CCR-04-0708","volume":"11","author":"A Misra","year":"2005","unstructured":"Misra A, Pellarin M, Nigro J, Smirnov I, Moore D, Lamborn KR, Pinkel D, Albertson DG, Feuerstein BG (2005) Array comparative genomic hybridization identifies genetic subgroups in grade 4 human astrocytomaClin Cancer Res 11:2907\u20132918","journal-title":"Clin Cancer Res"},{"key":"9076_CR25","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1007\/BF02281874","volume":"97","author":"LR Vitis De","year":"1996","unstructured":"De Vitis LR, Tedde A, Vitelli F, Ammannati F, Mennonna P, Bigozzi U, Montali E, Papi L (1996) Screening for mutations in the neurofibromatosis type 2 (NF2) gene in sporadic meningiomasHum Genet 97:632\u2013637","journal-title":"Hum Genet"},{"key":"9076_CR26","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1038\/22780","volume":"400","author":"WC Hahn","year":"1999","unstructured":"Hahn WC, Counter CM, Lundberg AS, Beijersbergen RL, Brooks MW, Weinberg RA (1999) Creation of human tumour cells with defined genetic elementsNature 400:464\u2013468","journal-title":"Nature"},{"key":"9076_CR27","first-page":"4956","volume":"61","author":"Y Sonoda","year":"2001","unstructured":"Sonoda Y, Ozawa T, Hirose Y, Aldape KD, McMahon M, Berger MS, Pieper RO (2001) Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytomaCancer Res 61:4956\u20134960","journal-title":"Cancer Res"},{"key":"9076_CR28","doi-asserted-by":"crossref","first-page":"303","DOI":"10.3171\/jns.2004.100.2.0303","volume":"100","author":"P Leuraud","year":"2004","unstructured":"Leuraud P, Dezamis E, Aguirre-Cruz L, Taillibert S, Lejeune J, Robin E, Mokhtari K, Boch AL, Cornu P, Delattre JY, Sanson M (2004) Prognostic value of allelic losses and telomerase activity in meningiomasJ Neurosurg 100:303\u2013309","journal-title":"J Neurosurg"},{"key":"9076_CR29","doi-asserted-by":"crossref","first-page":"832","DOI":"10.3171\/jns.2000.92.5.0832","volume":"92","author":"M Simon","year":"2003","unstructured":"Simon M, Park TW, Leuenroth S, Hans VH, Loning T, Schramm J (2003) Telomerase activity and expression of the telomerase catalytic subunit, hTERT, in meningioma progressionJ Neurosurg 92:832\u2013840","journal-title":"J Neurosurg"},{"key":"9076_CR30","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1038\/sj.onc.1205081","volume":"21","author":"AL Ducrest","year":"2002","unstructured":"Ducrest AL, Szutorisz H, Lingner J, Nabholz M (2002) Regulation of the human telomerase reverse transcriptase geneOncogene 21:541\u2013552","journal-title":"Oncogene"},{"key":"9076_CR31","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1038\/labinvest.3700307","volume":"85","author":"S Puttmann","year":"2005","unstructured":"Puttmann S, Senner V, Braune S, Hillmann B, Exeler R, Rickert CH, Paulus W Establishment of a benign meningioma cell line by hTERT-mediated immortalization Lab Invest 85 2005 1163\u20131171","journal-title":"Lab Invest"},{"key":"9076_CR32","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1023\/A:1013863630293","volume":"55","author":"M Simon","year":"2001","unstructured":"Simon M, Park TW, Koster G, Mahlberg R, Hackenbroch M, Bostrom J, Loning T, Schramm J (2001) Alterations of INK4a(p16-p14ARF)\/INK4b(p15) expression and telomerase activation in meningioma progressionJ Neurooncol 55:149\u2013158","journal-title":"J Neurooncol"},{"key":"9076_CR33","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1002\/(SICI)1098-2264(199712)20:4<419::AID-GCC15>3.0.CO;2-H","volume":"20","author":"KM Carlson","year":"1997","unstructured":"Carlson KM, Bruder C, Nordenskjold M, Dumanski JP (1997) 1p and 3p deletions in meningiomas without detectable aberrations of chromosome 22 identified by comparative genomic hybridizationGenes Chromosomes Cancer 20:419\u2013424","journal-title":"Genes Chromosomes Cancer"},{"key":"9076_CR34","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1097\/00001622-199507010-00011","volume":"7","author":"ML Smith","year":"1995","unstructured":"Smith ML, Fornace AJ (1995) Genomic instability and the role of p53 mutations in cancer cellsCurr Opin Oncol 7:69\u201375","journal-title":"Curr Opin Oncol"}],"container-title":["Journal of Neuro-Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11060-005-9076-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11060-005-9076-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11060-005-9076-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:18:52Z","timestamp":1559348332000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11060-005-9076-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3,23]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,6]]}},"alternative-id":["9076"],"URL":"https:\/\/doi.org\/10.1007\/s11060-005-9076-y","relation":{},"ISSN":["0167-594X","1573-7373"],"issn-type":[{"value":"0167-594X","type":"print"},{"value":"1573-7373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,3,23]]}}}