{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T04:17:12Z","timestamp":1791173832209,"version":"4.1.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2007,9,21]],"date-time":"2007-09-21T00:00:00Z","timestamp":1190332800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurooncol"],"published-print":{"date-parts":[[2007,10,18]]},"DOI":"10.1007\/s11060-007-9397-0","type":"journal-article","created":{"date-parts":[[2007,9,20]],"date-time":"2007-09-20T03:06:17Z","timestamp":1190257577000},"page":"207-211","source":"Crossref","is-referenced-by-count":122,"title":["Temozolomide and methotrexate for primary central nervous system lymphoma in the elderly"],"prefix":"10.1007","volume":"85","author":[{"given":"Antonio M. P.","family":"Omuro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc","family":"Taillandier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Chinot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Carnin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryline","family":"Barrie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khe","family":"Hoang-Xuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2007,9,21]]},"reference":[{"issue":"24","key":"9397_CR1","doi-asserted-by":"crossref","first-page":"4471","DOI":"10.1200\/JCO.2003.08.900","volume":"21","author":"LM DeAngelis","year":"2003","unstructured":"DeAngelis LM (2003) Primary central nervous system lymphoma: a curable brain tumor. J Clin Oncol 21(24):4471\u20134473","journal-title":"J Clin Oncol"},{"issue":"6 Suppl 19","key":"9397_CR2","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1053\/j.seminoncol.2003.11.032","volume":"30","author":"K Hoang-Xuan","year":"2003","unstructured":"Hoang-Xuan K, Chinot OL, Taillandier L (2003) Treatment of primary central nervous system lymphoma in the elderly. Semin Oncol 30(6 Suppl 19):53\u201357","journal-title":"Semin Oncol"},{"issue":"17","key":"9397_CR3","doi-asserted-by":"crossref","first-page":"3144","DOI":"10.1200\/JCO.2000.18.17.3144","volume":"18","author":"LE Abrey","year":"2000","unstructured":"Abrey LE, Yahalom J, DeAngelis LM (2000) Treatment for primary CNS lymphoma: the next step. J Clin Oncol 18(17):3144\u20133150","journal-title":"J Clin Oncol"},{"issue":"1","key":"9397_CR4","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1212\/01.WNL.0000148641.98241.5E","volume":"64","author":"AM Omuro","year":"2005","unstructured":"Omuro AM, DeAngelis LM, Yahalom J et\u00a0al (2005) Chemoradiotherapy for primary CNS lymphoma: an intent-to-treat analysis with complete follow-up. Neurology 64(1):69\u201374","journal-title":"Neurology"},{"issue":"10","key":"9397_CR5","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1001\/archneur.62.10.1595","volume":"62","author":"AM Omuro","year":"2005","unstructured":"Omuro AM, Ben-Porat LS, Panageas KS et\u00a0al (2005) Delayed neurotoxicity in primary central nervous system lymphoma. Arch Neurol 62(10):1595\u20131600","journal-title":"Arch Neurol"},{"issue":"1","key":"9397_CR6","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1200\/JCO.2002.20.1.231","volume":"20","author":"EM Bessell","year":"2002","unstructured":"Bessell EM, Lopez-Guillermo A, Villa S et al (2002) Importance of radiotherapy in the outcome of patients with primary CNS lymphoma: an analysis of the CHOD\/BVAM regimen followed by two different radiotherapy treatments. J Clin Oncol 20(1):231\u2013236","journal-title":"J Clin Oncol"},{"issue":"6","key":"9397_CR7","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1002\/ana.20495","volume":"57","author":"U Herrlinger","year":"2005","unstructured":"Herrlinger U, Kuker W, Uhl M et\u00a0al (2005) NOA-03 trial of high-dose methotrexate in primary central nervous system lymphoma: final report. Ann Neurol 57(6):843\u2013847","journal-title":"Ann Neurol"},{"issue":"6","key":"9397_CR8","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1200\/JCO.2003.03.036","volume":"21","author":"T Batchelor","year":"2003","unstructured":"Batchelor T, Carson K, O\u2019Neill A et\u00a0al (2003) Treatment of primary CNS lymphoma with methotrexate and deferred radiotherapy: a report of NABTT 96\u201307. J Clin Oncol 21(6):1044\u20131049","journal-title":"J Clin Oncol"},{"key":"9397_CR9","doi-asserted-by":"crossref","unstructured":"Omuro AM, Abrey LE (2006) Chemotherapy for primary central nervous system lymphoma. Neurosurg Focus 21(5):E12. Available via http:\/\/www.aans.org\/education\/journal\/neurosurgical\/Nov06\/21\u201315\u201312-1063.pdf","DOI":"10.3171\/foc.2006.21.5.13"},{"issue":"3","key":"9397_CR10","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1200\/JCO.2001.19.3.742","volume":"19","author":"C Soussain","year":"2001","unstructured":"Soussain C, Suzan F, Hoang-Xuan K et\u00a0al (2001) Results of intensive chemotherapy followed by hematopoietic stem-cell rescue in 22 patients with refractory or recurrent primary CNS lymphoma or intraocular lymphoma. J Clin Oncol 19(3):742\u2013749","journal-title":"J Clin Oncol"},{"key":"9397_CR11","doi-asserted-by":"crossref","unstructured":"Montemurro M, Kiefer T, Schuler F et\u00a0al (2006) Primary central nervous system lymphoma treated with high-dose methotrexate, high-dose busulfan\/thiotepa, autologous stem-cell transplantation and response-adapted whole-brain radiotherapy: results of the multicenter Ostdeutsche Studiengruppe Hamato-Onkologie OSHO-53 phase II study. Ann Oncol (in press), DOI 10.1093\/annonc\/mdl1458","DOI":"10.1093\/annonc\/mdl458"},{"issue":"6","key":"9397_CR12","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/sj.bmt.1705452","volume":"38","author":"P Colombat","year":"2006","unstructured":"Colombat P, Lemevel A, Bertrand P et\u00a0al (2006) High-dose chemotherapy with autologous stem cell transplantation as first-line therapy for primary CNS lymphoma in patients younger than 60\u00a0years: a multicenter phase II study of the GOELAMS group. Bone Marrow Transplant 38(6):417\u2013420","journal-title":"Bone Marrow Transplant"},{"issue":"24","key":"9397_CR13","doi-asserted-by":"crossref","first-page":"3865","DOI":"10.1200\/JCO.2006.06.2117","volume":"24","author":"G Illerhaus","year":"2006","unstructured":"Illerhaus G, Marks R, Ihorst G et\u00a0al (2006) High-dose chemotherapy with autologous stem-cell transplantation and hyperfractionated radiotherapy as first-line treatment of primary CNS lymphoma. J Clin Oncol 24(24):3865\u20133870","journal-title":"J Clin Oncol"},{"issue":"24","key":"9397_CR14","doi-asserted-by":"crossref","first-page":"4489","DOI":"10.1200\/JCO.2003.04.056","volume":"21","author":"H Pels","year":"2003","unstructured":"Pels H, Schmidt-Wolf IGH, Glasmacher A et\u00a0al (2003) Primary central nervous system lymphoma: results of a pilot and phase II study of systemic and intraventricular chemotherapy with deferred radiotherapy. J Clin Oncol 21(24):4489\u20134495","journal-title":"J Clin Oncol"},{"issue":"7","key":"9397_CR15","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1093\/jnci\/92.7.575","volume":"92","author":"M Reni","year":"2000","unstructured":"Reni M, Ferreri AJ, Landoni C et\u00a0al (2000) Salvage therapy with temozolomide in an immunocompetent patient with primary brain lymphoma. J Natl Cancer Inst 92(7):575\u2013576","journal-title":"J Natl Cancer Inst"},{"issue":"6","key":"9397_CR16","first-page":"4121","volume":"24","author":"HM Strik","year":"2004","unstructured":"Strik HM, Spreer A, Nagel H et\u00a0al (2004) Clinical response following adjuvant temozolomide in a patient with primary cerebral lymphoma. Anticancer Res 24(6):4121\u20134125","journal-title":"Anticancer Res"},{"issue":"11","key":"9397_CR17","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1016\/j.ejca.2004.03.008","volume":"40","author":"M Reni","year":"2004","unstructured":"Reni M, Mason W, Zaja F et\u00a0al (2004) Salvage chemotherapy with temozolomide in primary CNS lymphomas: preliminary results of a phase II trial. Eur J Cancer 40(11):1682\u20131688","journal-title":"Eur J Cancer"},{"issue":"10","key":"9397_CR18","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1212\/WNL.58.10.1573","volume":"58","author":"U Herrlinger","year":"2002","unstructured":"Herrlinger U, Kuker W, Platten M et\u00a0al (2002) First-line therapy with temozolomide induces regression of primary CNS lymphoma. Neurology 58(10):1573\u20131574","journal-title":"Neurology"},{"issue":"2","key":"9397_CR19","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1023\/A:1019682400415","volume":"59","author":"KA Lerro","year":"2002","unstructured":"Lerro KA, Lacy J (2002) Case report: a patient with primary CNS lymphoma treated with temozolomide to complete response. J Neurooncol 59(2):165\u2013168","journal-title":"J Neurooncol"},{"issue":"22","key":"9397_CR20","doi-asserted-by":"crossref","first-page":"5034","DOI":"10.1200\/JCO.2005.13.524","volume":"23","author":"LE Abrey","year":"2005","unstructured":"Abrey LE, Batchelor TT, Ferreri AJM et\u00a0al (2005) Report of an international workshop to standardize baseline evaluation and response criteria for primary CNS lymphoma. J Clin Oncol 23(22):5034\u20135043","journal-title":"J Clin Oncol"},{"issue":"36","key":"9397_CR21","doi-asserted-by":"crossref","first-page":"5711","DOI":"10.1200\/JCO.2006.08.2941","volume":"24","author":"LE Abrey","year":"2006","unstructured":"Abrey LE, Ben-Porat L, Panageas KS et\u00a0al (2006) Primary central nervous system lymphoma: the memorial Sloan-Kettering cancer center prognostic model. J Clin Oncol 24(36):5711\u20135715","journal-title":"J Clin Oncol"},{"issue":"2","key":"9397_CR22","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1200\/JCO.2003.09.139","volume":"21","author":"AJ Ferreri","year":"2003","unstructured":"Ferreri AJ, Blay JY, Reni M et\u00a0al (2003) Prognostic scoring system for primary CNS lymphomas: the International Extranodal Lymphoma Study Group experience. J Clin Oncol 21(2):266\u2013272","journal-title":"J Clin Oncol"},{"issue":"Suppl 2 II","key":"9397_CR23","first-page":"23","volume":"253","author":"A Juergens","year":"2006","unstructured":"Juergens A, Pels H, Schlegel U et\u00a0al (2006) Primary central nervous system lymphoma: results of a pilot and phase II study of systemic and intraventricular chemotherapy with deferred radiotherapy- final report. J Neurol 253(Suppl 2)II:23\u201324","journal-title":"J Neurol"},{"issue":"14","key":"9397_CR24","doi-asserted-by":"crossref","first-page":"2726","DOI":"10.1200\/JCO.2003.11.036","volume":"21","author":"K Hoang-Xuan","year":"2003","unstructured":"Hoang-Xuan K, Taillandier L, Chinot O et\u00a0al (2003) Chemotherapy alone as initial treatment for primary CNS lymphoma in patients older than 60\u00a0years: a multicenter phase II study (26952) of the European Organization for Research and Treatment of Cancer Brain Tumor Group. J Clin Oncol 21(14):2726\u20132731","journal-title":"J Clin Oncol"},{"issue":"3","key":"9397_CR25","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1093\/annonc\/mdi075","volume":"16","author":"K Jahnke","year":"2005","unstructured":"Jahnke K, Korfel A, Martus P et\u00a0al (2005) High-dose methotrexate toxicity in elderly patients with primary central nervous system lymphoma. Ann Oncol 16(3):445\u2013449","journal-title":"Ann Oncol"},{"issue":"10","key":"9397_CR26","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1056\/NEJMoa043331","volume":"352","author":"ME Hegi","year":"2005","unstructured":"Hegi ME, Diserens AC, Gorlia T et\u00a0al (2005) MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 352(10):997\u20131003","journal-title":"N Engl J Med"}],"container-title":["Journal of Neuro-Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11060-007-9397-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11060-007-9397-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11060-007-9397-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:19:04Z","timestamp":1559348344000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11060-007-9397-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9,21]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,10,18]]}},"alternative-id":["9397"],"URL":"https:\/\/doi.org\/10.1007\/s11060-007-9397-0","relation":{},"ISSN":["0167-594X","1573-7373"],"issn-type":[{"value":"0167-594X","type":"print"},{"value":"1573-7373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,9,21]]}}}