{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T20:39:51Z","timestamp":1762375191783},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2007,7,17]],"date-time":"2007-07-17T00:00:00Z","timestamp":1184630400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2007,7,17]],"date-time":"2007-07-17T00:00:00Z","timestamp":1184630400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurooncol"],"published-print":{"date-parts":[[2008,1]]},"DOI":"10.1007\/s11060-007-9450-z","type":"journal-article","created":{"date-parts":[[2007,7,17]],"date-time":"2007-07-17T00:08:05Z","timestamp":1184630885000},"page":"123-132","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Transient cerebral hypoperfusion enhances intraarterial carmustine deposition into brain tissue"],"prefix":"10.1007","volume":"86","author":[{"given":"Shailendra","family":"Joshi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua J.","family":"Etu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond F.","family":"Suckow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas B.","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven J.","family":"Feinmark","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey N.","family":"Bruce","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert L.","family":"Fine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2007,7,17]]},"reference":[{"issue":"3","key":"9450_CR1","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1097\/00130404-200305000-00009","volume":"9","author":"D Senger","year":"2003","unstructured":"Senger D, Cairncross JG, Forsyth PA (2003) Long-term survivors of glioblastoma: statistical aberration or important unrecognized molecular subtype?[see comment]. Cancer J 9(3):214\u2013221","journal-title":"Cancer J"},{"issue":"10","key":"9450_CR2","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1593\/neo.05307","volume":"7","author":"S Wemmert","year":"2005","unstructured":"Wemmert S, Ketter R, Rahnenfuhrer J, Beerenwinkel N, Strowitzki M, Feiden W, Hartmann C, Lengauer T, Stockhammer F, Zang KD, Meese E, Steudel WI, von Deimling A, Urbschat S (2005) Patients with high-grade gliomas harboring deletions of chromosomes 9p and 10q benefit from temozolomide treatment. Neoplasia 7(10):883\u2013893","journal-title":"Neoplasia"},{"issue":"1","key":"9450_CR3","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1007\/s11060-006-9159-4","volume":"80","author":"P Sampath","year":"2006","unstructured":"Sampath P, Rhines LD, DiMeco F, Tyler BM, Park MC, Brem H et al (2006) Interstitial docetaxel (Taxotere), carmustine and combined interstitial therapy: a novel treatment for experimental malignant glioma. J Neurooncol 80(1):9\u201317","journal-title":"J Neurooncol"},{"issue":"2","key":"9450_CR4","doi-asserted-by":"publisher","first-page":"e2","DOI":"10.3171\/foc.2003.14.2.3","volume":"14","author":"WA Hall","year":"2003","unstructured":"Hall WA, Rustamzadeh E, Asher AL (2003) Convection-enhanced delivery in clinical trials. Neurosurg Focus 14(2):e2","journal-title":"Neurosurg Focus"},{"issue":"3","key":"9450_CR5","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1002\/ana.410140310","volume":"14","author":"EA Neuwelt","year":"1983","unstructured":"Neuwelt EA, Glasberg M, Frenkel E, Barnett P, (1983) Neurotoxicity of chemotherapeutic agents after blood-brain barrier modification: neuropathological studies. Ann Neurol 14(3):316\u2013324","journal-title":"Ann Neurol"},{"issue":"2","key":"9450_CR6","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1093\/jnci\/80.2.84","volume":"80","author":"RL Dedrick","year":"1988","unstructured":"Dedrick RL (1988) Arterial drug infusion: pharmacokinetic problems and pitfalls. J Natl Cancer Inst 80(2):84\u201389","journal-title":"J Natl Cancer Inst"},{"key":"9450_CR7","first-page":"1045","volume-title":"Neuroradiology","author":"J Pile-Spellman","year":"1996","unstructured":"Pile-Spellman J (1996) Endovascular therapeutic neuroradiology (Chapter 18). In: Taveras JM (ed) Neuroradiology, 3rd edn. Williams and Wilkins, Baltimore, pp 1045\u20131179","edition":"3"},{"issue":"2","key":"9450_CR8","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1097\/00008506-200604000-00004","volume":"18","author":"S Joshi","year":"2006","unstructured":"Joshi S, Wang M, Etu J, Nishanian EV (2006) Comparison of intracarotid anesthetics for EEG silence. J Neurosurg Anesthesiol 18(2):112\u2013118","journal-title":"J Neurosurg Anesthesiol"},{"issue":"2","key":"9450_CR9","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1097\/00000542-200602000-00014","volume":"104","author":"S Joshi","year":"2006","unstructured":"Joshi S, Wang M, Etu JJ, Nishanian EV, Pile-Spellman J (2006) Cerebral blood flow affects dose requirements of intracarotid propofol for electrocerebral silence. Anesthesiology 104(2):290\u2013298, discussion 5A","journal-title":"Anesthesiology"},{"issue":"7","key":"9450_CR10","first-page":"877","volume":"70","author":"WD Henner","year":"1986","unstructured":"Henner WD, Peters WP, Eder JP, Antman K, Schnipper L, Frei E III (1986) Pharmacokinetics and immediate effects of high-dose carmustine in man. Cancer Treat Rep 70(7):877\u2013880","journal-title":"Cancer Treat Rep"},{"issue":"2","key":"9450_CR11","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1161\/01.STR.25.2.501","volume":"25","author":"JS Lee","year":"1994","unstructured":"Lee JS, Hamilton MG, Zabramski JM (1994) Variations in the anatomy of the rabbit cervical carotid artery. Stroke 25(2):501\u2013503","journal-title":"Stroke"},{"issue":"1","key":"9450_CR12","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/BF01054276","volume":"17","author":"DJ Stewart","year":"1993","unstructured":"Stewart DJ, Grahovac Z, Hugenholtz H, DaSilva V, Richard MT, Benoit B, Belanger G, Russell N (1993) Feasibility study of intraarterial vs intravenous cisplatin, BCNU, and teniposide combined with systemic cisplatin, teniposide, cytosine arabinoside, glycerol and mannitol in the treatment of primary and metastatic brain tumors. J Neurooncol 17(1):71\u201379","journal-title":"J Neurooncol"},{"issue":"2","key":"9450_CR13","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1007\/BF01078489","volume":"24","author":"DJ Stewart","year":"1995","unstructured":"Stewart DJ, Dahrouge S, Wee M, Aitken S, Hugenholtz H (1995) Intraarterial cisplatin plus intravenous doxorubicin for inoperable recurrent meningiomas. J Neurooncol 24(2):189\u2013194","journal-title":"J Neurooncol"},{"issue":"1","key":"9450_CR14","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1007\/BF00177438","volume":"30","author":"SJ Hassenbusch","year":"1996","unstructured":"Hassenbusch SJ, Anderson JH, Colvin OM (1996) Predicted and actual BCNU concentrations in normal rabbit brain during intraarterial and intravenous infusions. J Neurooncol 30(1):7\u201318","journal-title":"J Neurooncol"},{"issue":"3","key":"9450_CR15","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1097\/01.WCB.0000107731.66603.18","volume":"24","author":"S Joshi","year":"2004","unstructured":"Joshi S, Wang M, Hartl R (2004) Retinal Discoloration test. J Cereb Blood Flow Metab 24(3):305\u2013308","journal-title":"J Cereb Blood Flow Metab"},{"issue":"6","key":"9450_CR16","doi-asserted-by":"publisher","first-page":"1816","DOI":"10.1213\/01.ane.0000202523.94060.47","volume":"102","author":"S Joshi","year":"2006","unstructured":"Joshi S, Wang M, Etu JJ, Pile-Spellman J (2006) Bolus configuration affects dose requirements of intracarotid propofol for electroencephalographic silence. Anesth Analg 102(6):1816\u20131822","journal-title":"Anesth Analg"},{"issue":"3","key":"9450_CR17","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1213\/01.ANE.0000160583.42078.B2","volume":"101","author":"S Joshi","year":"2005","unstructured":"Joshi S, Wang M, Etu JJ, Pile-Spellman J. (2005) Reducing cerebral blood flow increases the duration of electroencephalographic silence by intracarotid thiopental. Anesth Analg 101(3):851\u2013858","journal-title":"Anesth Analg"},{"issue":"7","key":"9450_CR18","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1002\/jps.2600840711","volume":"84","author":"SJ Hassenbusch","year":"1995","unstructured":"Hassenbusch SJ, Colvin OM, Anderson JH (1995) Determination of nitrosourea compounds in brain tissue by gas chromatography and electron capture detection. J Pharm Sci 84(7):840\u2013842","journal-title":"J Pharm Sci"},{"issue":"2","key":"9450_CR19","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/0378-4347(95)00430-0","volume":"677","author":"JG Supko","year":"1996","unstructured":"Supko JG, Phillips LR, Malspeis L (1996) Specific high-performance liquid chromatographic assay with ultraviolet detection for the determination of 1-(2-chloroethyl)-3-sarcosinamide-1-nitrosourea in plasma. J Chromatogr B Biomed Appl 677(2):351\u2013362","journal-title":"J Chromatogr B Biomed Appl"},{"issue":"4","key":"9450_CR20","doi-asserted-by":"publisher","first-page":"1140","DOI":"10.1213\/01.ANE.0000147510.25610.9C","volume":"100","author":"R Hartl","year":"2005","unstructured":"Hartl R et al (2005) Pial arterial response to topical verapamil in acute closed cranial windows in rabbits. Anesth Analg 100(4):1140\u20131146","journal-title":"Anesth Analg"},{"issue":"6","key":"9450_CR21","doi-asserted-by":"publisher","first-page":"1498","DOI":"10.1213\/01.ane.0000264089.72804.54","volume":"104","author":"M Wang","year":"2007","unstructured":"Wang M, Joshi S (2007) Electrocerebral silence after intracarotid propofol is a function of transit time. Anesth Analg 104(6):1498\u20131503","journal-title":"Anesth Analg"},{"issue":"Suppl 2","key":"9450_CR22","first-page":"27","volume":"65","author":"J Fenstermacher","year":"1981","unstructured":"Fenstermacher J, Gazendam J (1981) Intra-arterial infusions of drugs and hyperosmotic solutions as ways of enhancing CNS chemotherapy. Cancer Treat Rep 65(Suppl 2):27\u201337","journal-title":"Cancer Treat Rep"},{"key":"9450_CR23","unstructured":"Allman JM (1999) The evolution of big brains, 1st edn. Evolving brains in Scientific American Library, New York, pp 158\u2013208"},{"issue":"5","key":"9450_CR24","doi-asserted-by":"crossref","first-page":"763","DOI":"10.3171\/jns.1991.74.5.0763","volume":"74","author":"SC Saris","year":"1991","unstructured":"Saris SC, Blasberg RG, Carson RE, deVroom HL, Lutz R, Dedrick RL, Pettigrew K, Chang R, Doppman J, Wright DC et al (1991) Intravascular streaming during carotid artery infusions. Demonstration in humans and reduction using diastole-phased pulsatile administration. J Neurosurg 74(5):763\u2013772","journal-title":"J Neurosurg"},{"issue":"5","key":"9450_CR25","doi-asserted-by":"crossref","first-page":"721","DOI":"10.3171\/jns.1987.67.5.0721","volume":"67","author":"SC Saris","year":"1987","unstructured":"Saris SC, Shook DR, Blasberg RG, Dedrick RL, Doppman JL, Bankiewicz KS, Blacklock JB, Oldfield EH (1987) Carotid artery mixing with diastole-phased pulsed drug infusion. J Neurosurg 67(5):721\u2013725","journal-title":"J Neurosurg"},{"issue":"2","key":"9450_CR26","doi-asserted-by":"publisher","first-page":"277","DOI":"10.3171\/jns.1986.64.2.0277","volume":"64","author":"RJ Lutz","year":"1986","unstructured":"Lutz RJ, Dedrick RL, Boretos JW, Oldfield EH, Blacklock JB, Doppman JL (1986) Mixing studies during intracarotid artery infusions in an in vitro model. J Neurosurgery 64(2):277\u2013283","journal-title":"J Neurosurgery"},{"issue":"4","key":"9450_CR27","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1097\/00006123-199904000-00117","volume":"44","author":"J Pile-Spellman","year":"1999","unstructured":"Pile-Spellman J, Young WL, Joshi S, Duong H, Vang MC, Hartmann A, Kahn RA, Rubin DA, Prestigiacomo CJ, Ostapkovich ND (1999) Adenosine-induced cardiac pause for endovascular embolization of cerebral arteriovenous malformations: technical case report. Neurosurgery 44(4):881\u2013886","journal-title":"Neurosurgery"},{"issue":"4","key":"9450_CR28","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1097\/00000542-200010000-00021","volume":"93","author":"T Hashimoto","year":"2000","unstructured":"Hashimoto T, Young WL, Aagaard BD, Joshi S, Ostapkovich ND, Pile-Spellman J (2000) Adenosine-induced ventricular asystole to induce transient profound systemic hypotension in patients undergoing endovascular therapy: dose-response characteristics. Anesthesiology 93(4):998\u20131001","journal-title":"Anesthesiology"},{"issue":"3","key":"9450_CR29","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1007\/BF00165608","volume":"1","author":"BH Smith","year":"1983","unstructured":"Smith BH, Vaughan M, Greenwood MA, Kornblith PL, Robinson A, Shitara N, McKeever PE (1983) Membrane and cytoplasmic changes in 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU)-sensitive and resistant human malignant glioma-derived cell lines. J Neurooncol 1(3):237\u2013248","journal-title":"J Neurooncol"},{"issue":"3","key":"9450_CR30","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1148\/radiology.218.3.r01mr41724","volume":"218","author":"YP Gobin","year":"2001","unstructured":"Gobin YP, Cloughesy TF, Chow KL, Duckwiler GR, Sayre JW, Milanese K, Vinuela F (2001) Intraarterial chemotherapy for brain tumors by using a spatial dose fractionation algorithm and pulsatile delivery. Radiology 218(3):724\u2013732","journal-title":"Radiology"},{"issue":"3","key":"9450_CR31","first-page":"293","volume":"69","author":"EH Oldfield","year":"1985","unstructured":"Oldfield EH, Dedrick RL, Chatterji DC, Yeager RL, Girton ME, Kornblith PL, Doppman JL (1985) Arterial drug infusion with extracorporeal removal. II. Internal carotid carmustine in the rhesus monkey. Cancer Treat Rep 69(3):293\u2013303","journal-title":"Cancer Treat Rep"},{"issue":"3","key":"9450_CR32","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1021\/tx00033a020","volume":"6","author":"MR Davis","year":"1993","unstructured":"Davis MR, Kassahun K, Jochheim CM, Brandt KM, Baillie TA (1993) Glutathione and N-acetylcysteine conjugates of 2-chloroethyl isocyanate. Identification as metabolites of N,N\u2032-bis(2-chloroethyl)-N-nitrosourea in the rat and inhibitory properties toward glutathione reductase in vitro. Chemical Res Toxicol 6(3):376\u2013383","journal-title":"Chemical Res Toxicol"}],"container-title":["Journal of Neuro-Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11060-007-9450-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11060-007-9450-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11060-007-9450-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11060-007-9450-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,15]],"date-time":"2022-05-15T19:40:08Z","timestamp":1652643608000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11060-007-9450-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7,17]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["9450"],"URL":"https:\/\/doi.org\/10.1007\/s11060-007-9450-z","relation":{},"ISSN":["0167-594X","1573-7373"],"issn-type":[{"value":"0167-594X","type":"print"},{"value":"1573-7373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,7,17]]},"assertion":[{"value":"8 January 2007","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 June 2007","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 July 2007","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}