{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T18:51:11Z","timestamp":1715971871701},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2016,7,9]],"date-time":"2016-07-09T00:00:00Z","timestamp":1468022400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurooncol"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1007\/s11060-016-2205-y","type":"journal-article","created":{"date-parts":[[2016,7,9]],"date-time":"2016-07-09T06:41:30Z","timestamp":1468046490000},"page":"405-413","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Expression of p40 (\u2206Np63) protein in meningiomas, an unexpected finding: immunohistochemical study and evaluation of its possible prognostic role"],"prefix":"10.1007","volume":"129","author":[{"given":"Elia","family":"Guadagno","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marialaura","family":"Del Basso De Caro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Pignatiello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Concetta","family":"Sciammarella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Solari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Cappabianca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Maiuri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flavia","family":"Dones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,7,9]]},"reference":[{"key":"2205_CR1","first-page":"164","volume-title":"WHO classification of tumours of the central nervous system","author":"A Perry","year":"2007","unstructured":"Perry A, Louis DN, Scheithauer BW et al (2007) Meningiomas. In: Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (eds) WHO classification of tumours of the central nervous system. IARC, Lyon, pp\u00a0164\u2013172"},{"key":"2205_CR2","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1097\/00000478-199712000-00008","volume":"21","author":"A Perry","year":"1997","unstructured":"Perry A, Stafford SL, Scheithauer BW et al (1997) Meningioma grading: an analysis of histologic parameters. Am J Surg Pathol 21:1455\u20131465","journal-title":"Am J Surg Pathol"},{"key":"2205_CR3","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/j.1440-1789.2007.00750.x","volume":"27","author":"J Bruna","year":"2007","unstructured":"Bruna J, Brell M, Ferrer I et al (2007) Ki67 proliferative index predicts clinical outcome in patients with atypical or anaplastic meningioma. Neuropathology 27:114\u2013120","journal-title":"Neuropathology"},{"key":"2205_CR4","first-page":"37","volume":"25","author":"V Karja","year":"2006","unstructured":"Karja V, Alafuzoff I (2006) Protein p62 common in invaginations in benign meningioma- a possible predictor of malignancy. ClinNeuropathol 25:37\u201343","journal-title":"ClinNeuropathol"},{"key":"2205_CR5","first-page":"203","volume":"125","author":"HP Hahn","year":"2006","unstructured":"Hahn HP, Bundock EA, Hornick JL (2006) Immunohistochemical staining for claudin-1 can help distiguishmeningiomas from histologic mimics. Am J ClinPathol 125:203\u2013208","journal-title":"Am J ClinPathol"},{"key":"2205_CR6","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1093\/jnen\/59.10.872","volume":"59","author":"A Perry","year":"2000","unstructured":"Perry A, Cai DX, Scheithauer BW et al (2000) Merlin, DAL-1, and progesterone receptor expression in clinico-pathologic subsets of meningioma: a correlative immunohistochemical study of 175 cases. J Neuropathol Exp Neurol 59:872\u2013879","journal-title":"J Neuropathol Exp Neurol"},{"key":"2205_CR7","doi-asserted-by":"crossref","first-page":"210","DOI":"10.3171\/jns.2004.101.2.0210","volume":"101","author":"O Al-Mefty","year":"2004","unstructured":"Al-Mefty O, Kadri PA, Pravdenkova S et al (2004) Malignant progression in meningioma: documentation of a series and analysis of cytogenetic findings. J Neurosurg 101:210\u2013218","journal-title":"J Neurosurg"},{"key":"2205_CR8","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1093\/jnen\/60.6.628","volume":"60","author":"DX Cai","year":"2001","unstructured":"Cai DX, Banerjee R, Scheithauer BW et al (2001) Chromosome 1p and 14q FISH analysis, in clinicopathologic subsets of meningioma; diagnostic and prognostic implications. J Neuropathol Exp Neurol 60:628\u2013636","journal-title":"J Neuropathol Exp Neurol"},{"key":"2205_CR9","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djv377","author":"F Sahm","year":"2015","unstructured":"Sahm F, Schrimpf D, OlarAet al (2015)TERT promoter mutations and risk of recurrence in meningioma. J Natl Cancer Inst. doi: 10.1093\/jnci\/djv377","journal-title":"J Natl Cancer Inst"},{"issue":"4","key":"2205_CR10","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1227\/NEU.0b013e3181eb95b7","volume":"67","author":"A Vranic","year":"2010","unstructured":"Vranic A, Poponic M, Cor A et al (2010) Mitotic count, brain invasion, and location are independent predictors of recurrence-free survival in primary atypical and malignant meningiomas: a study of 86 patients. Neurosurg 67(4):1124\u20131132","journal-title":"Neurosurg"},{"key":"2205_CR11","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/s11864-004-0038-y","volume":"5","author":"KP McMullen","year":"2004","unstructured":"McMullen KP, Stieber VW (2004) Meningioma: current treatment options and future directions. Curr Treat Options Oncl 5: 499\u2013509","journal-title":"Curr Treat Options Oncl"},{"issue":"4","key":"2205_CR12","doi-asserted-by":"crossref","first-page":"376","DOI":"10.4103\/0028-3886.141248","volume":"62","author":"S Kumar","year":"2014","unstructured":"Kumar S, Kakkar A, Suri V et al (2014) Evaluation of 1p and 14q status, MIB-1 labeling index and progesterone receptor immunoexpression in meningiomas: adjuncts to histopathological grading and predictors of aggressive behavior. Neurol India 62(4):376\u2013382","journal-title":"Neurol India"},{"key":"2205_CR13","first-page":"142","volume":"48","author":"N Shayanfar","year":"2010","unstructured":"Shayanfar N, Mashayekh M, Mohammadpour M (2010) Expression of progestrone receptor and proliferative marker Ki 67 in various grades of meningioma. Acta Med Iran 48:142\u2013147","journal-title":"Acta Med Iran"},{"key":"2205_CR14","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1038\/sj.onc.1201500","volume":"15","author":"H Schmale","year":"1997","unstructured":"Schmale H, Bamberger C (1997) A novel protein with strong homology to the tumor suppressor p53. Oncogene 15:1367","journal-title":"Oncogene"},{"key":"2205_CR15","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S1097-2765(00)80275-0","volume":"2","author":"A Yang","year":"1998","unstructured":"Yang A, Kagdah M, Wang Y et al (1998) p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death inducing, and dominan-negative activities. Mol Cell 2:305\u2013315","journal-title":"Mol Cell"},{"key":"2205_CR16","first-page":"337","volume":"12","author":"SI Meredith","year":"2001","unstructured":"Meredith SI, Kaelin WG (2001) P53 family update: p73 and p63 develop their own identities. Cell Growth Diff 12:337\u2013349","journal-title":"Cell Growth Diff"},{"key":"2205_CR17","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1054\/bjoc.2000.1735","volume":"84","author":"M Senoo","year":"2001","unstructured":"Senoo M, Tsuchiya I, Matsumura Y et al (2001) Transcriptional dysregulation of the p73L\/p63\/p51\/p40\/KET gene in human squamous cell carcinoma: expression of \u2206Np73 L, a novel dominant-negative isoform, and loss of expression of the potential tumour suppressor p51. Br J Cancer 84:1235\u20131241","journal-title":"Br J Cancer"},{"key":"2205_CR18","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/19531","volume":"398","author":"AA Mills","year":"1999","unstructured":"Mills AA, Zheng B, Wang XJ et al (1999) p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 398:708\u2013713","journal-title":"Nature"},{"key":"2205_CR19","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1038\/19539","volume":"398","author":"A Yang","year":"1999","unstructured":"Yang A, Schweitzer R, Sun D et al (1999) p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 398:714\u2013718","journal-title":"Nature"},{"key":"2205_CR20","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1093\/carcin\/21.2.153","volume":"21","author":"PA Hall","year":"2000","unstructured":"Hall PA, Campbell SJ, O\u2019Neill M et al (2000) The expression of the p53 homologue, p63\u03b1 and \u2206Np63\u03b1 in normal and neoplastic cells. Carcinogenesis 21:153\u2013160","journal-title":"Carcinogenesis"},{"key":"2205_CR21","doi-asserted-by":"crossref","first-page":"3156","DOI":"10.1073\/pnas.061032098","volume":"13","author":"G Pellegrini","year":"2001","unstructured":"Pellegrini G, Dellambra E, Golisano O et al (2001) p63 identifieskeratinocytestemcells. Proc Natl Acad Sci USA 13:3156\u20133161","journal-title":"Proc Natl Acad Sci USA"},{"key":"2205_CR22","first-page":"1769","volume":"157","author":"S Signoretti","year":"2000","unstructured":"Signoretti S, Waltgreny D, Dilks J et al (2000) p63 is a prostate basal cell marker and is required fr prostate development. AmJPathol 157:1769\u20131775","journal-title":"AmJPathol"},{"key":"2205_CR23","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1097\/00000478-200108000-00010","volume":"25","author":"BarbareschiM","year":"2001","unstructured":"BarbareschiM, Pecciarini L, Cangi MG et al (2001) P63, a p53 homologue, is a selective marker of myoepitelial cells of the human breast. Am J SurgPathol 25:1054\u20131060","journal-title":"Am J SurgPathol"},{"key":"2205_CR24","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1002\/path.1231","volume":"198","author":"K Nylander","year":"2002","unstructured":"Nylander K, Vojtesek B, Nenutil R et al (2002) Differential expression of p63 isoforms in normal tissues and neoplastic cells. J Pathol 198:417\u2013427","journal-title":"J Pathol"},{"key":"2205_CR25","first-page":"411A","volume":"23","author":"G Pelosi","year":"2010","unstructured":"Pelosi G, Sonzogni A, Papotti M, et al (2010) Different prevalence of transactivating (TA) p63 and nonTAp63 isoforms in pulmonary adenocarcinomas: a useful diagnostic tool. Mod Pathol 23:411A\u2013412A","journal-title":"Mod Pathol"},{"key":"2205_CR26","first-page":"S335","volume":"6","author":"G Pelosi","year":"2011","unstructured":"Pelosi G, fabbri A, Rossi G et al (2011) A two-hit minimalist diagnostic algorithm based on p40 (deltaNp63) and TTF1 immunostaining upon small biopsy\/cell block samples for differentiating main subtypes of non- small cell lung cancer and sparing material. J Thor Oncol 6:S335\u2013S336","journal-title":"J Thor Oncol"},{"key":"2205_CR27","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/modpathol.2011.173","volume":"25","author":"JA Bishop","year":"2012","unstructured":"Bishop JA, Teruya-Feldstein J, Westra WH et al (2012) p40 (\u2206Np63) is superior to p63 for the diagnosis of pulmonary squamous cell carcinoma. Mod Pathol 25:405\u2013415","journal-title":"Mod Pathol"},{"key":"2205_CR28","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s00428-003-0857-4","volume":"443","author":"M Chilosi","year":"2003","unstructured":"Chilosi M, Zamo A, Brighenti A et al (2003) Constitutive expression of DeltaN-p63alpha isoform in human thymus and thymic epithelial tumors. Virchows Arch 443:175\u2013183","journal-title":"Virchows Arch"},{"key":"2205_CR29","doi-asserted-by":"crossref","first-page":"5462","DOI":"10.1073\/pnas.97.10.5462","volume":"97","author":"K Hibi","year":"2000","unstructured":"Hibi K, Trink B, Patturajan M et al (2000) AIS is an oncogene amplified in squamous cell carcinoma. Proc Natl Acad Sci USA 97:5462\u20135467","journal-title":"Proc Natl Acad Sci USA"},{"key":"2205_CR30","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/S0046-8177(03)00342-3","volume":"34","author":"H Geddert","year":"2003","unstructured":"Geddert H, Kiel S, Heep HJ et al (2003) The role of p63 and delta Np63 (p40) protein expression and gene amplification in esophageal carcinogenensis. Hum Pathol 34:850\u2013856","journal-title":"Hum Pathol"},{"key":"2205_CR31","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1016\/j.ajpath.2010.11.061","volume":"178","author":"O Karni-Schmidt","year":"2011","unstructured":"Karni-Schmidt O, Castillo-Martin M, Huaishen T et al (2011) Distinct expression profiles of p63 variants during urothelial development and bladder cancer progression. Am J Pathol 178:1350\u20131360","journal-title":"Am J Pathol"},{"key":"2205_CR32","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1097\/01.pas.0000130325.66448.a1","volume":"28","author":"IM Shih","year":"2004","unstructured":"Shih IM, Kurman RJ (2004) P63 expression is useful in the distinction of epithelioid trophoblastic subpopulations. Am J Surg Pathol 28:1177\u20131183","journal-title":"Am J Surg Pathol"},{"key":"2205_CR33","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1177\/1066896907306772","volume":"16","author":"EJ Rushing","year":"2008","unstructured":"Rushing EJ, Olsen C, Man YG (2008) Correlation of p63 immunoreactivity with tumor grade in meningiomas. Int J Surg Pathol 16:38\u201342","journal-title":"Int J Surg Pathol"},{"issue":"4","key":"2205_CR34","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1177\/1066896911434549","volume":"20","author":"SuchiM","year":"2012","unstructured":"SuchiM, Deepali J, Subimal R et al (2012) Correlation of p63 Protein expression with histological grade of meningioma: an immunohistochemical study. Int J Surg Pathol 20(4):349\u2013354","journal-title":"Int J Surg Pathol"},{"key":"2205_CR35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/2016.1.JNS151842","volume":"8","author":"A Nanda","year":"2016","unstructured":"Nanda A, Bir SC, Maiti TK et al (2016) Relevance of Simpson grading system and recurrence-free survival after surgery for World Health Organization grade I meningioma. J Neurosurg 8:1\u201311","journal-title":"J Neurosurg"},{"key":"2205_CR36","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.3171\/2010.3.JNS091971","volume":"113","author":"ME Sughrue","year":"2010","unstructured":"Sughrue ME, Kane AJ, Shangari G et al (2010) The relevance of Simpson Grade I and II resection in modern neurosurgical treatment of World Health Organization Grade I meningiomas. J Neurosurg 113:1029\u20131035","journal-title":"J Neurosurg"},{"key":"2205_CR37","first-page":"466","volume":"25","author":"L LoMuzio","year":"2007","unstructured":"LoMuzio L, Campisi G, Farina A (2007) Effect of p63 expression on survival in oral squamous cell carcinoma. Cancer Invest 25:466\u2013469","journal-title":"Cancer Invest"},{"key":"2205_CR38","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1034\/j.1600-0714.2000.290901.x","volume":"29","author":"K Nylander","year":"2000","unstructured":"Nylander K, Dabelsteen E, Hall PA (2000) The p53 molecule and its role in squamous cell carcinomas of the head and neck. J Oral Pathol Med 29:413\u2013425","journal-title":"J Oral Pathol Med"},{"key":"2205_CR39","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1097\/00005072-198609000-00008","volume":"45","author":"R O\u2019Rahilly","year":"1986","unstructured":"O\u2019Rahilly R, Muller F (1986) The meninges in human development. J Neuro Pathol Exp Neurol 45:588\u2013608","journal-title":"J Neuro Pathol Exp Neurol"},{"key":"2205_CR40","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.acthis.2010.09.005","volume":"113","author":"J Petricevic","year":"2011","unstructured":"Petricevic J, Forempoher G, OstohicLjerka (2011) Expression of nestin, mesothelin and epithelial membrane antigen (EMA) in developing and adult human meninges and meningiomas. Acta Histochemica 113:703\u2013711","journal-title":"Acta Histochemica"},{"key":"2205_CR41","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.cell.2007.02.045","volume":"129","author":"M Senoo","year":"2007","unstructured":"Senoo M, Pinto F, Crum CP et al (2007) P63 is essential for the proliferative potential of stem cells in stratified epithelia. Cell 129:523\u2013536","journal-title":"Cell"},{"key":"2205_CR42","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.humpath.2014.11.011","volume":"46","author":"K Uchida","year":"2015","unstructured":"Uchida K, Ross H, Lotan T et al (2015) \u2206Np63 (p40) expression in prostatic adenocarcinoma with diffuse p63 positivity. Hum Pathol 46:384\u2013389","journal-title":"Hum Pathol"}],"container-title":["Journal of Neuro-Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11060-016-2205-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11060-016-2205-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11060-016-2205-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T18:06:55Z","timestamp":1498327615000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11060-016-2205-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,9]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["2205"],"URL":"https:\/\/doi.org\/10.1007\/s11060-016-2205-y","relation":{},"ISSN":["0167-594X","1573-7373"],"issn-type":[{"value":"0167-594X","type":"print"},{"value":"1573-7373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,9]]}}}