{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T21:21:05Z","timestamp":1784582465314,"version":"3.55.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"National Science and Technology Council, Taiwan","award":["111-2926-I-075-501-G"],"award-info":[{"award-number":["111-2926-I-075-501-G"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurooncol"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1007\/s11060-023-04512-2","type":"journal-article","created":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T11:02:16Z","timestamp":1700478136000},"page":"343-351","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Treatment and survival of patients with small cell lung cancer and brain metastasis"],"prefix":"10.1007","volume":"165","author":[{"given":"Chi-Lu","family":"Chiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huai-Che","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Ting","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yung-Hung","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan-Hung","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsiu-Mei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuh-Min","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,11,20]]},"reference":[{"key":"4512_CR1","doi-asserted-by":"publisher","first-page":"1921","DOI":"10.1002\/cncr.30000","volume":"122","author":"PH Goncalves","year":"2016","unstructured":"Goncalves PH, Peterson SL, Vigneau FD, Shore RD, Quarshie WO, Islam K, Schwartz AG, Wozniak AJ, Gadgeel SM (2016) Risk of brain metastases in patients with nonmetastatic Lung cancer: analysis of the Metropolitan Detroit Surveillance, Epidemiology, and end results (SEER) data. Cancer 122:1921\u20131927. https:\/\/doi.org\/10.1002\/cncr.30000","journal-title":"Cancer"},{"key":"4512_CR2","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1002\/1097-0142(19830201)51:3<529::aid-cncr2820510327>3.0.co;2-0","volume":"51","author":"FR Hirsch","year":"1983","unstructured":"Hirsch FR, Paulson OB, Hansen HH, Larsen SO (1983) Intracranial metastases in small cell carcinoma of the lung. Prognostic aspects. Cancer 51:529\u2013533. https:\/\/doi.org\/10.1002\/1097-0142(19830201)51:3<529::aid-cncr2820510327>3.0.co;2-0","journal-title":"Cancer"},{"key":"4512_CR3","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.lungcan.2014.07.020","volume":"86","author":"M Riihim\u00e4ki","year":"2014","unstructured":"Riihim\u00e4ki M, Hemminki A, Fallah M, Thomsen H, Sundquist K, Sundquist J, Hemminki K (2014) Metastatic sites and survival in Lung cancer. Lung Cancer 86:78\u201384. https:\/\/doi.org\/10.1016\/j.lungcan.2014.07.020","journal-title":"Lung Cancer"},{"key":"4512_CR4","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.lungcan.2016.09.010","volume":"101","author":"D Bernhardt","year":"2016","unstructured":"Bernhardt D, Bozorgmehr F, Adeberg S, Opfermann N, von Eiff D, Rieber J, Kappes J, Foerster R, K\u00f6nig L, Thomas M, Debus J, Steins M, Rieken S (2016) Outcome in patients with small cell Lung cancer re-irradiated for brain metastases after prior prophylactic cranial irradiation. Lung Cancer 101:76\u201381. https:\/\/doi.org\/10.1016\/j.lungcan.2016.09.010","journal-title":"Lung Cancer"},{"key":"4512_CR5","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.ijrobp.2006.08.019","volume":"67","author":"GM Videtic","year":"2007","unstructured":"Videtic GM, Adelstein DJ, Mekhail TM, Rice TW, Stevens GH, Lee SY, Suh JH (2007) Validation of the RTOG recursive partitioning analysis (RPA) classification for small-cell lung cancer-only brain metastases. Int J Radiat Oncol Biol Phys 67:240\u2013243. https:\/\/doi.org\/10.1016\/j.ijrobp.2006.08.019","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"4512_CR6","doi-asserted-by":"publisher","first-page":"1441","DOI":"10.6004\/jnccn.2021.0058","volume":"19","author":"AKP Ganti","year":"2021","unstructured":"Ganti AKP, Loo BW, Bassetti M, Blakely C, Chiang A, D\u2019Amico TA, D\u2019Avella C, Dowlati A, Downey RJ, Edelman M, Florsheim C, Gold KA, Goldman JW, Grecula JC, Hann C, Iams W, Iyengar P, Kelly K, Khalil M, Koczywas M, Merritt RE, Mohindra N, Molina J, Moran C, Pokharel S, Puri S, Qin A, Rusthoven C, Sands J, Santana-Davila R, Shafique M, Waqar SN, Gregory KM, Hughes M (2021) Small cell Lung Cancer, Version 2.2022, NCCN Clinical Practice guidelines in Oncology. J Natl Compr Cancer Network: JNCCN 19:1441\u20131464. https:\/\/doi.org\/10.6004\/jnccn.2021.0058","journal-title":"J Natl Compr Cancer Network: JNCCN"},{"key":"4512_CR7","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1056\/NEJMoa071780","volume":"357","author":"B Slotman","year":"2007","unstructured":"Slotman B, Faivre-Finn C, Kramer G, Rankin E, Snee M, Hatton M, Postmus P, Collette L, Musat E, Senan S (2007) Prophylactic cranial irradiation in extensive small-cell Lung cancer. N Engl J Med 357:664\u2013672. https:\/\/doi.org\/10.1056\/NEJMoa071780","journal-title":"N Engl J Med"},{"key":"4512_CR8","doi-asserted-by":"publisher","first-page":"e199135","DOI":"10.1001\/jamanetworkopen.2019.9135","volume":"2","author":"O Gjyshi","year":"2019","unstructured":"Gjyshi O, Ludmir EB, Pezzi TA, Boyce-Fappiano D, Dursteler AE, Mitin T, Lin SH (2019) Evolving practice patterns in the use of prophylactic cranial irradiation for extensive-stage small cell Lung Cancer. JAMA Netw open 2:e199135\u2013e199135. https:\/\/doi.org\/10.1001\/jamanetworkopen.2019.9135","journal-title":"JAMA Netw open"},{"key":"4512_CR9","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1016\/s1470-2045(17)30230-9","volume":"18","author":"T Takahashi","year":"2017","unstructured":"Takahashi T, Yamanaka T, Seto T, Harada H, Nokihara H, Saka H, Nishio M, Kaneda H, Takayama K, Ishimoto O, Takeda K, Yoshioka H, Tachihara M, Sakai H, Goto K, Yamamoto N (2017) Prophylactic cranial irradiation versus observation in patients with extensive-disease small-cell Lung cancer: a multicentre, randomised, open-label, phase 3 trial. Lancet Oncol 18:663\u2013671. https:\/\/doi.org\/10.1016\/s1470-2045(17)30230-9","journal-title":"Lancet Oncol"},{"key":"4512_CR10","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/s13014-022-01994-8","volume":"17","author":"YJ Lim","year":"2022","unstructured":"Lim YJ, Song C, Kim HJ (2022) Survival impact of prophylactic cranial irradiation in small-cell Lung cancer in the modern era of magnetic resonance imaging staging. Radiation Oncol (London England) 17:26. https:\/\/doi.org\/10.1186\/s13014-022-01994-8","journal-title":"Radiation Oncol (London England)"},{"key":"4512_CR11","doi-asserted-by":"publisher","unstructured":"Lee CC, Hsu SPC, Lin CJ, Wu HM, Chen YW, Luo YH, Chiang CL, Hu YS, Chung WY, Shiau CY, Guo WY, Hung-Chi Pan D, Yang HC (2019) Epidermal growth factor receptor mutations: association with favorable local Tumor control following Gamma Knife Radiosurgery in patients with non-small cell Lung cancer and brain metastases. J Neurosurg 1\u20138. https:\/\/doi.org\/10.3171\/2019.4.jns19446","DOI":"10.3171\/2019.4.jns19446"},{"key":"4512_CR12","doi-asserted-by":"publisher","first-page":"2483","DOI":"10.1001\/jama.295.21.2483","volume":"295","author":"H Aoyama","year":"2006","unstructured":"Aoyama H, Shirato H, Tago M, Nakagawa K, Toyoda T, Hatano K, Kenjyo M, Oya N, Hirota S, Shioura H, Kunieda E, Inomata T, Hayakawa K, Katoh N, Kobashi G (2006) Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial. JAMA 295:2483\u20132491. https:\/\/doi.org\/10.1001\/jama.295.21.2483","journal-title":"JAMA"},{"key":"4512_CR13","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1016\/s1470-2045(22)00271-6","volume":"23","author":"K Gaebe","year":"2022","unstructured":"Gaebe K, Li AY, Park A, Parmar A, Lok BH, Sahgal A, Chan KKW, Erickson AW, Das S (2022) Stereotactic radiosurgery versus whole brain radiotherapy in patients with intracranial metastatic Disease and small-cell Lung cancer: a systematic review and meta-analysis. Lancet Oncol 23:931\u2013939. https:\/\/doi.org\/10.1016\/s1470-2045(22)00271-6","journal-title":"Lancet Oncol"},{"key":"4512_CR14","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1093\/neuros\/nyz428","volume":"87","author":"CP Cifarelli","year":"2020","unstructured":"Cifarelli CP, Vargo JA, Fang W, Liscak R, Guseynova K, Warnick RE, Lee CC, Yang HC, Borghei-Razavi H, Maiti T, Siddiqui ZA, Yuan JC, Grills IS, Mathieu D, Touchette CJ, Cordeiro D, Chiang V, Hess J, Tien CJ, Faramand A, Kano H, Barnett GH, Sheehan JP, Lunsford LD (2020) Role of Gamma Knife Radiosurgery in Small Cell Lung Cancer: a multi-institutional Retrospective Study of the International Radiosurgery Research Foundation (IRRF). Neurosurgery 87:664\u2013671. https:\/\/doi.org\/10.1093\/neuros\/nyz428","journal-title":"Neurosurgery"},{"key":"4512_CR15","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1080\/0284186x.2018.1562207","volume":"58","author":"W Jiang","year":"2019","unstructured":"Jiang W, Haque W, Verma V, Butler B, Teh BS (2019) Stereotactic radiosurgery for brain metastases from newly diagnosed small cell Lung cancer: practice patterns and outcomes. Acta Oncol (Stockholm Sweden) 58:491\u2013498. https:\/\/doi.org\/10.1080\/0284186x.2018.1562207","journal-title":"Acta Oncol (Stockholm Sweden)"},{"key":"4512_CR16","doi-asserted-by":"publisher","first-page":"1599","DOI":"10.1016\/j.mayocp.2019.01.034","volume":"94","author":"S Wang","year":"2019","unstructured":"Wang S, Zimmermann S, Parikh K, Mansfield AS, Adjei AA (2019) Current diagnosis and management of small-cell Lung Cancer. Mayo Clin Proc 94:1599\u20131622. https:\/\/doi.org\/10.1016\/j.mayocp.2019.01.034","journal-title":"Mayo Clin Proc"},{"key":"4512_CR17","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1038\/nrclinonc.2017.71","volume":"14","author":"JK Sabari","year":"2017","unstructured":"Sabari JK, Lok BH, Laird JH, Poirier JT, Rudin CM (2017) Unravelling the biology of SCLC: implications for therapy. Nat Rev Clin Oncol 14:549\u2013561. https:\/\/doi.org\/10.1038\/nrclinonc.2017.71","journal-title":"Nat Rev Clin Oncol"},{"key":"4512_CR18","doi-asserted-by":"publisher","first-page":"2220","DOI":"10.1056\/NEJMoa1809064","volume":"379","author":"L Horn","year":"2018","unstructured":"Horn L, Mansfield AS, Szczesna A, Havel L, Krzakowski M, Hochmair MJ, Huemer F, Losonczy G, Johnson ML, Nishio M, Reck M, Mok T, Lam S, Shames DS, Liu J, Ding B, Lopez-Chavez A, Kabbinavar F, Lin W, Sandler A, Liu SV (2018) First-line atezolizumab plus chemotherapy in extensive-stage small-cell Lung Cancer. N Engl J Med 379:2220\u20132229. https:\/\/doi.org\/10.1056\/NEJMoa1809064","journal-title":"N Engl J Med"},{"key":"4512_CR19","doi-asserted-by":"publisher","first-page":"1929","DOI":"10.1016\/s0140-6736(19)32222-6","volume":"394","author":"L Paz-Ares","year":"2019","unstructured":"Paz-Ares L, Dvorkin M, Chen Y, Reinmuth N, Hotta K, Trukhin D, Statsenko G, Hochmair MJ, Ozguroglu M, Ji JH, Voitko O, Poltoratskiy A, Ponce S, Verderame F, Havel L, Bondarenko I, Kazarnowicz A, Losonczy G, Conev NV, Armstrong J, Byrne N, Shire N, Jiang H, Goldman JW (2019) Durvalumab plus platinum-etoposide versus platinum-etoposide in first-line treatment of extensive-stage small-cell Lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial. Lancet (London England) 394:1929\u20131939. https:\/\/doi.org\/10.1016\/s0140-6736(19)32222-6","journal-title":"Lancet (London England)"},{"key":"4512_CR20","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1016\/j.jtho.2019.12.109","volume":"15","author":"HC Chung","year":"2020","unstructured":"Chung HC, Piha-Paul SA, Lopez-Martin J, Schellens JHM, Kao S, Miller WH Jr., Delord JP, Gao B, Planchard D, Gottfried M, Zer A, Jalal SI, Penel N, Mehnert JM, Matos I, Bennouna J, Kim DW, Xu L, Krishnan S, Norwood K, Ott PA (2020) Pembrolizumab after two or more lines of previous therapy in patients with recurrent or metastatic SCLC: results from the KEYNOTE-028 and KEYNOTE-158 studies. J Thorac Oncol 15:618\u2013627. https:\/\/doi.org\/10.1016\/j.jtho.2019.12.109","journal-title":"J Thorac Oncol"},{"key":"4512_CR21","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1016\/j.ijrobp.2018.02.175","volume":"101","author":"E Schapira","year":"2018","unstructured":"Schapira E, Hubbeling H, Yeap BY, Mehan WA Jr., Shaw AT, Oh K, Gainor JF, Shih HA (2018) Improved overall survival and Locoregional Disease Control with concurrent PD-1 pathway inhibitors and stereotactic radiosurgery for Lung Cancer patients with brain metastases. Int J Radiat Oncol Biol Phys 101:624\u2013629. https:\/\/doi.org\/10.1016\/j.ijrobp.2018.02.175","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"4512_CR22","doi-asserted-by":"publisher","unstructured":"Chiou GY, Chiang CL, Yang HC, Shen CI, Wu HM, Chen YW, Chen CJ, Luo YH, Hu YS, Lin CJ, Chung WY, Shiau CY, Guo WY, Pan DH, Lee CC (2021) Combined stereotactic radiosurgery and tyrosine kinase inhibitor therapy versus tyrosine kinase inhibitor therapy alone for the treatment of non-small cell Lung cancer patients with brain metastases. J Neurosurg 1\u20138. https:\/\/doi.org\/10.3171\/2021.9.jns211373","DOI":"10.3171\/2021.9.jns211373"},{"key":"4512_CR23","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1007\/s11060-018-2980-8","volume":"140","author":"CC Lee","year":"2018","unstructured":"Lee CC, Chou CL, Chen CJ, Yang HC, Wu HM, Shiau CY, Pan DH, Chung WY (2018) Stereotactic radiosurgery for hypervascular intracranial tumors. J Neurooncol 140:547\u2013558. https:\/\/doi.org\/10.1007\/s11060-018-2980-8","journal-title":"J Neurooncol"},{"key":"4512_CR24","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/s0360-3016(99)00507-6","volume":"47","author":"E Shaw","year":"2000","unstructured":"Shaw E, Scott C, Souhami L, Dinapoli R, Kline R, Loeffler J, Farnan N (2000) Single dose radiosurgical treatment of recurrent previously irradiated primary brain tumors and brain metastases: final report of RTOG protocol 90 \u2013 05. Int J Radiat Oncol Biol Phys 47:291\u2013298. https:\/\/doi.org\/10.1016\/s0360-3016(99)00507-6","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"4512_CR25","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1097\/coc.0000000000000867","volume":"44","author":"R Rittberg","year":"2021","unstructured":"Rittberg R, Banerji S, Kim JO, Rathod S, Dawe DE (2021) Treatment and Prevention of Brain metastases in Small Cell Lung Cancer. Am J Clin Oncol 44:629\u2013638. https:\/\/doi.org\/10.1097\/coc.0000000000000867","journal-title":"Am J Clin Oncol"},{"key":"4512_CR26","doi-asserted-by":"publisher","first-page":"1929","DOI":"10.1016\/s0140-6736(19)32222-6","volume":"394","author":"L Paz-Ares","year":"2019","unstructured":"Paz-Ares L, Dvorkin M, Chen Y, Reinmuth N, Hotta K, Trukhin D, Statsenko G, Hochmair MJ, \u00d6zg\u00fcro\u011flu M, Ji JH, Voitko O, Poltoratskiy A, Ponce S, Verderame F, Havel L, Bondarenko I, Kazarnowicz A, Losonczy G, Conev NV, Armstrong J, Byrne N, Shire N, Jiang H, Goldman JW (2019) Durvalumab plus platinum-etoposide versus platinum-etoposide in first-line treatment of extensive-stage small-cell Lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial. Lancet (London England) 394:1929\u20131939. https:\/\/doi.org\/10.1016\/s0140-6736(19)32222-6","journal-title":"Lancet (London England)"},{"key":"4512_CR27","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.1001\/jamaoncol.2020.1271","volume":"6","author":"CG Rusthoven","year":"2020","unstructured":"Rusthoven CG, Yamamoto M, Bernhardt D, Smith DE, Gao D, Serizawa T, Yomo S, Aiyama H, Higuchi Y, Shuto T, Akabane A, Sato Y, Niranjan A, Faramand AM, Lunsford LD, McInerney J, Tuanquin LC, Zacharia BE, Chiang V, Singh C, Yu JB, Braunstein S, Mathieu D, Touchette CJ, Lee CC, Yang HC, Aizer AA, Cagney DN, Chan MD, Kondziolka D, Bernstein K, Silverman JS, Grills IS, Siddiqui ZA, Yuan JC, Sheehan JP, Cordeiro D, Nosaki K, Seto T, Deibert CP, Verma V, Day S, Halasz LM, Warnick RE, Trifiletti DM, Palmer JD, Attia A, Li B, Cifarelli CP, Brown PD, Vargo JA, Combs SE, Kessel KA, Rieken S, Patel S, Guckenberger M, Andratschke N, Kavanagh BD, Robin TP (2020) Evaluation of first-line Radiosurgery vs whole-brain radiotherapy for small cell Lung Cancer Brain metastases: the FIRE-SCLC Cohort Study. JAMA Oncol 6:1028\u20131037. https:\/\/doi.org\/10.1001\/jamaoncol.2020.1271","journal-title":"JAMA Oncol"},{"key":"4512_CR28","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1016\/j.ijrobp.2021.10.008","volume":"112","author":"RO Kowalchuk","year":"2022","unstructured":"Kowalchuk RO, Niranjan A, Lee CC, Yang HC, Liscak R, Guseynova K, Tripathi M, Kumar N, Peker S, Samanci Y, Hess J, Chiang V, Iorio-Morin C, Mathieu D, Pikis S, Wei Z, Lunsford LD, Trifiletti DM, Sheehan JP (2022) Reirradiation with Stereotactic Radiosurgery after local or marginal recurrence of Brain metastases from previous Radiosurgery. Int J Radiat Oncol Biol Phys 112:726\u2013734. https:\/\/doi.org\/10.1016\/j.ijrobp.2021.10.008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"4512_CR29","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1007\/s11060-019-03323-8","volume":"145","author":"C Iorio-Morin","year":"2019","unstructured":"Iorio-Morin C, Mercure-Cyr R, Figueiredo G, Touchette CJ, Masson-C\u00f4t\u00e9 L, Mathieu D (2019) Repeat stereotactic radiosurgery for the management of locally recurrent brain metastases. J Neurooncol 145:551\u2013559. https:\/\/doi.org\/10.1007\/s11060-019-03323-8","journal-title":"J Neurooncol"},{"key":"4512_CR30","doi-asserted-by":"publisher","first-page":"1825","DOI":"10.1007\/s00432-022-04121-y","volume":"149","author":"J Chang","year":"2023","unstructured":"Chang J, Jing X, Hua Y, Geng K, Li R, Lu S, Zhu H, Zhang Y (2023) Programmed cell death 1 pathway inhibitors improve the overall survival of small cell Lung cancer patients with brain metastases. J Cancer Res Clin Oncol 149:1825\u20131833. https:\/\/doi.org\/10.1007\/s00432-022-04121-y","journal-title":"J Cancer Res Clin Oncol"},{"key":"4512_CR31","doi-asserted-by":"publisher","first-page":"2893","DOI":"10.1200\/jco.22.02823","volume":"41","author":"L Paz-Ares","year":"2023","unstructured":"Paz-Ares L, Champiat S, Lai WV, Izumi H, Govindan R, Boyer M, Hummel HD, Borghaei H, Johnson ML, Steeghs N, Blackhall F, Dowlati A, Reguart N, Yoshida T, He K, Gadgeel SM, Felip E, Zhang Y, Pati A, Minocha M, Mukherjee S, Goldrick A, Nagorsen D, Hashemi Sadraei N, Owonikoko TK (2023) Tarlatamab, a first-in-class DLL3-Targeted bispecific T-Cell engager, in recurrent small-cell Lung Cancer: an Open-Label, phase I study. J Clin Oncology: Official J Am Soc Clin Oncol 41:2893\u20132903. https:\/\/doi.org\/10.1200\/jco.22.02823","journal-title":"J Clin Oncology: Official J Am Soc Clin Oncol"},{"key":"4512_CR32","doi-asserted-by":"publisher","first-page":"932105","DOI":"10.3389\/fonc.2022.932105","volume":"12","author":"A Manzo","year":"2022","unstructured":"Manzo A, Sforza V, Carillio G, Palumbo G, Montanino A, Sandomenico C, Costanzo R, Esposito G, Laudato F, Mercadante E, La Manna C, Muto P, Totaro G, De Cecio R, Picone C, Piccirillo MC, Pascarella G, Normanno N, Morabito A (2022) Lurbinectedin in small cell Lung cancer. Front Oncol 12:932105. https:\/\/doi.org\/10.3389\/fonc.2022.932105","journal-title":"Front Oncol"}],"container-title":["Journal of Neuro-Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11060-023-04512-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11060-023-04512-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11060-023-04512-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:27:03Z","timestamp":1701390423000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11060-023-04512-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["4512"],"URL":"https:\/\/doi.org\/10.1007\/s11060-023-04512-2","relation":{},"ISSN":["0167-594X","1573-7373"],"issn-type":[{"value":"0167-594X","type":"print"},{"value":"1573-7373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"15 October 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 November 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 November 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Institutional Review Board of Taipei Veterans General Hospital, Taiwan (approval number: 2023-06-016CC).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was waived due to retrospective design.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not appliable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"CLC has received honoraria from AstraZeneca, Boehringer Ingelheim, Pfizer, and Roche. YHL has received honoraria from AstraZeneca, Boehringer Ingelheim, and Pfizer.YMC has received honoraria from Boehringer Ingelheim, Eli Lilly, Roche\/Genentech\/Chugai, MSD, Pfizer, Novartis, BMS, Ono Pharmaceutical, AstraZeneca, and Takeda Oncology and provided advisory services to Boehringer Ingelheim, Eli Lilly, Roche\/Chugai, MSD, AstraZeneca, and Takeda Oncology.The other authors declare no conflicts of interest relevant to the content of this manuscript.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}