{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T08:17:56Z","timestamp":1794385076575,"version":"4.9.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T00:00:00Z","timestamp":1752537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T00:00:00Z","timestamp":1752537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Maltepe University"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurooncol"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>Spinal ependymomas are the most common intramedullary spinal cord tumors, with surgical resection being the primary treatment modality. This study aimed to evaluate the prognostic value of preoperative MRI features in predicting motor deficits in patients undergoing surgery for spinal ependymomas.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>We retrospectively analyzed 71 patients with histopathologically confirmed spinal ependymomas who underwent surgical resection between 2009 and 2021. Preoperative MRI features\u2014including tumor volume, cystic components, syrinx formation, intratumoral hemorrhage, and longitudinal tumor extension\u2014were assessed. Motor strength was recorded pre- and postoperatively. Statistical analysis included univariate comparisons and multivariate logistic regression to identify independent predictors of neurological deficits.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Preoperative motor weakness was significantly associated with syrinx formation (<jats:italic>p<\/jats:italic>\u2009=\u20090.012), intratumoral hemorrhage (<jats:italic>p<\/jats:italic>\u2009=\u20090.015), and greater tumor length (<jats:italic>p<\/jats:italic>\u2009=\u20090.037). Postoperative motor deterioration was significantly correlated with intratumoral hemorrhage (<jats:italic>p<\/jats:italic>\u2009=\u20090.025), increased tumor volume (<jats:italic>p<\/jats:italic>\u2009=\u20090.007), and longitudinal extension (<jats:italic>p<\/jats:italic>\u2009=\u20090.001). In multivariate analysis, the number of vertebral levels involved was the only independent predictor of postoperative motor weakness (OR\u2009=\u20091.737; 95% CI: 1.063\u20132.838; <jats:italic>p<\/jats:italic>\u2009=\u20090.028). No independent predictors were identified for preoperative weakness, although syrinx formation showed a trend toward significance.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Preoperative MRI findings\u2014particularly intratumoral hemorrhage, syrinx formation, and longitudinal extension\u2014are associated with motor deficits in spinal ependymomas. However, only longitudinal tumor extension was an independent predictor of postoperative neurological deterioration. These findings highlight the importance of comprehensive radiological assessment in preoperative planning and risk stratification. Small sample size and short-term postoperative assessment represent important limitations of this study.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s11060-025-05134-6","type":"journal-article","created":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T09:49:00Z","timestamp":1752572940000},"page":"313-322","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The role of MRI patterns in predicting neurologic deficits in spinal ependymomas"],"prefix":"10.1007","volume":"175","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2325-3903","authenticated-orcid":false,"given":"Caner","family":"Sar\u0131kaya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4312-5685","authenticated-orcid":false,"given":"Cumhur Kaan","family":"Yalt\u0131r\u0131k","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3135-849X","authenticated-orcid":false,"given":"Ey\u00fcp","family":"Varol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2945-743X","authenticated-orcid":false,"given":"Evren","family":"Y\u00fcvr\u00fck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4353-9068","authenticated-orcid":false,"given":"Mehmet Re\u015fit","family":"\u00d6nen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6784-4270","authenticated-orcid":false,"given":"Sait","family":"Naderi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,15]]},"reference":[{"key":"5134_CR1","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1186\/1756-0500-7-908","volume":"7","author":"A Bostrom","year":"2014","unstructured":"Bostrom A, Kanther NC, Grote A, Bostrom J (2014) Management and outcome in adult intramedullary spinal cord tumours: a 20-year single institution experience. 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All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional and national research committee, as well as the 1964 Helsinki Declaration and its later amendments.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Due to the retrospective nature of the study, formal informed consent was waived by the ethics committee. However, patient data confidentiality and privacy were strictly maintained throughout the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}