{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T23:04:40Z","timestamp":1785539080106,"version":"3.56.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurooncol"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1007\/s11060-026-05595-3","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T04:54:48Z","timestamp":1778561688000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Stereotactic radiosurgery for pediatric craniopharyngiomas: a multicenter retrospective study"],"prefix":"10.1007","volume":"177","author":[{"given":"Luigi","family":"Albano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Losa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaetano Giulio","family":"Vitale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jheremy Sebastian","family":"Reyes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella","family":"Del Vecchio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriella","family":"Pozzobon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei","family":"Fodor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Acerno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constantinos George","family":"Hadjipanayis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Di Muzio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina Raffaella","family":"Barzaghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John C.","family":"Flickinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Mortini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence Dade","family":"Lunsford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Niranjan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,12]]},"reference":[{"key":"5595_CR1","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1210\/er.2013-1115","volume":"35","author":"HL Muller","year":"2014","unstructured":"Muller HL (2014) Craniopharyngioma Endocr Rev 35:513\u2013543. https:\/\/doi.org\/10.1210\/er.2013-1115","journal-title":"Craniopharyngioma Endocr Rev"},{"key":"5595_CR2","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1111\/j.1365-2265.2005.02231.x","volume":"62","author":"N Karavitaki","year":"2005","unstructured":"Karavitaki N, Brufani C, Warner JT, Adams CB, Richards P, Ansorge O, Shine B, Turner HE, Wass JA (2005) Craniopharyngiomas in children and adults: systematic analysis of 121 cases with long-term follow-up. Clin Endocrinol (Oxf) 62:397\u2013409. https:\/\/doi.org\/10.1111\/j.1365-2265.2005.02231.x","journal-title":"Clin Endocrinol (Oxf)"},{"key":"5595_CR3","doi-asserted-by":"publisher","first-page":"293","DOI":"10.3171\/2012.7.PEDS11436","volume":"10","author":"AJ Clark","year":"2012","unstructured":"Clark AJ, Cage TA, Aranda D, Parsa AT, Auguste KI, Gupta N (2012) Treatment-related morbidity and the management of pediatric craniopharyngioma: a systematic review. J Neurosurg Pediatr 10:293\u2013301. https:\/\/doi.org\/10.3171\/2012.7.PEDS11436","journal-title":"J Neurosurg Pediatr"},{"key":"5595_CR4","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1159\/000493061","volume":"34","author":"A Niranjan","year":"2019","unstructured":"Niranjan A, Lunsford LD (2019) The Role of Leksell Radiosurgery in the Management of Craniopharyngiomas. Prog Neurol Surg 34:166\u2013172. https:\/\/doi.org\/10.1159\/000493061","journal-title":"Prog Neurol Surg"},{"key":"5595_CR5","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1007\/s00381-005-1202-9","volume":"21","author":"T Tomita","year":"2005","unstructured":"Tomita T, Bowman RM (2005) Craniopharyngiomas in children: surgical experience at Children\u2019s Memorial Hospital. Childs Nerv Syst 21:729\u2013746. https:\/\/doi.org\/10.1007\/s00381-005-1202-9","journal-title":"Childs Nerv Syst"},{"key":"5595_CR6","doi-asserted-by":"publisher","first-page":"848","DOI":"10.1159\/000506902","volume":"110","author":"L Albano","year":"2020","unstructured":"Albano L, Losa M, Flickinger J, Mortini P, Minniti G (2020) Radiotherapy of Parasellar Tumours. Neuroendocrinology 110:848\u2013858. https:\/\/doi.org\/10.1159\/000506902","journal-title":"Neuroendocrinology"},{"key":"5595_CR7","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1159\/000163383","volume":"22","author":"T Kobayashi","year":"2009","unstructured":"Kobayashi T (2009) Long-term results of gamma knife radiosurgery for 100 consecutive cases of craniopharyngioma and a treatment strategy. Prog Neurol Surg 22:63\u201376. https:\/\/doi.org\/10.1159\/000163383","journal-title":"Prog Neurol Surg"},{"key":"5595_CR8","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1007\/s11102-018-0903-5","volume":"21","author":"M Losa","year":"2018","unstructured":"Losa M, Pieri V, Bailo M, Gagliardi F, Barzaghi LR, Gioia L, Del Vecchio A, Bolognesi A, Mortini P (2018) Single fraction and multisession Gamma Knife radiosurgery for craniopharyngioma. Pituitary 21:499\u2013506. https:\/\/doi.org\/10.1007\/s11102-018-0903-5","journal-title":"Pituitary"},{"key":"5595_CR9","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1007\/s10143-009-0186-4","volume":"32","author":"G Minniti","year":"2009","unstructured":"Minniti G, Esposito V, Amichetti M, Enrici RM (2009) The role of fractionated radiotherapy and radiosurgery in the management of patients with craniopharyngioma. Neurosurg Rev 32:125\u2013132 discussion 132. https:\/\/doi.org\/10.1007\/s10143-009-0186-4","journal-title":"Neurosurg Rev"},{"key":"5595_CR10","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.ijrobp.2009.07.1693","volume":"78","author":"A Niranjan","year":"2010","unstructured":"Niranjan A, Kano H, Mathieu D, Kondziolka D, Flickinger JC, Lunsford LD (2010) Radiosurgery for craniopharyngioma. Int J Radiat Oncol Biol Phys 78:64\u201371. https:\/\/doi.org\/10.1016\/j.ijrobp.2009.07.1693","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"5595_CR11","doi-asserted-by":"publisher","first-page":"613","DOI":"10.3171\/jns.2002.97.supplement","volume":"97","author":"E Ulfarsson","year":"2002","unstructured":"Ulfarsson E, Lindquist C, Roberts M, Rahn T, Lindquist M, Thoren M, Lippitz B (2002) Gamma knife radiosurgery for craniopharyngiomas: long-term results in the first Swedish patients. J Neurosurg 97:613\u2013622. https:\/\/doi.org\/10.3171\/jns.2002.97.supplement","journal-title":"J Neurosurg"},{"key":"5595_CR12","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1530\/EJE-11-0158","volume":"165","author":"HL Muller","year":"2011","unstructured":"Muller HL, Gebhardt U, Teske C, Faldum A, Zwiener I, Warmuth-Metz M, Pietsch T, Pohl F, Sorensen N, Calaminus G, Study Committee of K (2011) Post-operative hypothalamic lesions and obesity in childhood craniopharyngioma: results of the multinational prospective trial KRANIOPHARYNGEOM 2000 after 3-year follow-up. Eur J Endocrinol 165:17\u201324. https:\/\/doi.org\/10.1530\/EJE-11-0158","journal-title":"Eur J Endocrinol"},{"key":"5595_CR13","doi-asserted-by":"publisher","first-page":"94","DOI":"10.3171\/ped.2006.104.2.5","volume":"104","author":"TE Merchant","year":"2006","unstructured":"Merchant TE, Kiehna EN, Kun LE, Mulhern RK, Li C, Xiong X, Boop FA, Sanford RA (2006) Phase II trial of conformal radiation therapy for pediatric patients with craniopharyngioma and correlation of surgical factors and radiation dosimetry with change in cognitive function. J Neurosurg 104:94\u2013102. https:\/\/doi.org\/10.3171\/ped.2006.104.2.5","journal-title":"J Neurosurg"},{"key":"5595_CR14","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.radonc.2014.11.035","volume":"114","author":"BJ Greenfield","year":"2015","unstructured":"Greenfield BJ, Okcu MF, Baxter PA, Chintagumpala M, Teh BS, Dauser RC, Su J, Desai SS, Paulino AC (2015) Long-term disease control and toxicity outcomes following surgery and intensity modulated radiation therapy (IMRT) in pediatric craniopharyngioma. Radiother Oncol 114:224\u2013229. https:\/\/doi.org\/10.1016\/j.radonc.2014.11.035","journal-title":"Radiother Oncol"},{"key":"5595_CR15","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1093\/neuonc\/noae204","volume":"27","author":"ES Murphy","year":"2025","unstructured":"Murphy ES, Sahgal A, Regis J, Levivier M, Fariselli L, Gorgulho A, Ma L, Pollock B, Yomo S, Sheehan J, Paddick I, Suh JH, Saxena A, Ahmed MA, Kotecha R (2025) Pediatric cranial stereotactic radiosurgery: Meta-analysis and international stereotactic radiosurgery society practice guidelines. Neuro Oncol 27:517\u2013532. https:\/\/doi.org\/10.1093\/neuonc\/noae204","journal-title":"Neuro Oncol"},{"key":"5595_CR16","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1016\/j.ijrobp.2013.06.2047","volume":"87","author":"JA Leavitt","year":"2013","unstructured":"Leavitt JA, Stafford SL, Link MJ, Pollock BE (2013) Long-term evaluation of radiation-induced optic neuropathy after single-fraction stereotactic radiosurgery. Int J Radiat Oncol Biol Phys 87:524\u2013527. https:\/\/doi.org\/10.1016\/j.ijrobp.2013.06.2047","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"5595_CR17","doi-asserted-by":"publisher","first-page":"S28","DOI":"10.1016\/j.ijrobp.2009.07.1753","volume":"76","author":"C Mayo","year":"2010","unstructured":"Mayo C, Martel MK, Marks LB, Flickinger J, Nam J, Kirkpatrick J (2010) Radiation dose-volume effects of optic nerves and chiasm. Int J Radiat Oncol Biol Phys 76:S28\u201335. https:\/\/doi.org\/10.1016\/j.ijrobp.2009.07.1753","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"5595_CR18","doi-asserted-by":"publisher","unstructured":"Albano L, Losa M, Barzaghi LR, Niranjan A, Siddiqui Z, Flickinger JC, Lunsford LD, Mortini P (2021) Gamma Knife Radiosurgery for Pituitary Tumors: A Systematic Review and Meta-Analysis. Cancers (Basel) 13. https:\/\/doi.org\/10.3390\/cancers13194998","DOI":"10.3390\/cancers13194998"},{"key":"5595_CR19","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1227\/neu.0000000000002886","volume":"95","author":"L Albano","year":"2024","unstructured":"Albano L, Losa M, Barzaghi LR, Barrile E, Bindal SK, Wei Z, Pompeo E, Villanacci F, Del Vecchio A, Flickinger JC, Niranjan A, Mortini P, Lunsford LD (2024) Single Versus Fractionated Gamma Knife Radiosurgery for Nonfunctioning Pituitary Adenomas Close to the Optic Pathway: A Multicenter Propensity Score Matched Study. Neurosurgery 95:357\u2013364. https:\/\/doi.org\/10.1227\/neu.0000000000002886","journal-title":"Neurosurgery"},{"key":"5595_CR20","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1007\/s11060-021-03806-7","volume":"154","author":"A Ogino","year":"2021","unstructured":"Ogino A, Niranjan A, Kano H, Flickinger JC, Lunsford LD (2021) Optimizing stereotactic radiosurgery in patients with recurrent or residual craniopharyngiomas. J Neurooncol 154:113\u2013120. https:\/\/doi.org\/10.1007\/s11060-021-03806-7","journal-title":"J Neurooncol"},{"key":"5595_CR21","doi-asserted-by":"publisher","unstructured":"Kobayashi T, Tanaka T, Kida Y (1994) Stereotactic gamma radiosurgery of craniopharyngiomas. Pediatr Neurosurg 21 Suppl 169\u201374. https:\/\/doi.org\/10.1159\/000120865","DOI":"10.1159\/000120865"},{"key":"5595_CR22","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1093\/neuonc\/3.3.159","volume":"3","author":"SM Chiou","year":"2001","unstructured":"Chiou SM, Lunsford LD, Niranjan A, Kondziolka D, Flickinger JC (2001) Stereotactic radiosurgery of residual or recurrent craniopharyngioma, after surgery, with or without radiation therapy. Neuro Oncol 3:159\u2013166. https:\/\/doi.org\/10.1093\/neuonc\/3.3.159","journal-title":"Neuro Oncol"},{"key":"5595_CR23","doi-asserted-by":"publisher","first-page":"e6973","DOI":"10.7759\/cureus.6973","volume":"12","author":"T Tsugawa","year":"2020","unstructured":"Tsugawa T, Kobayashi T, Hasegawa T, Iwai Y, Matsunaga S, Yamamoto M, Hayashi M, Kenai H, Kano T, Mori H, Nagano O, Hasegawa S, Inoue A, Nagatomo Y, Onoue S, Sato M, Yasuda S (2020) Gamma Knife Surgery for Residual or Recurrent Craniopharyngioma After Surgical Resection: A Multi-institutional Retrospective Study in Japan. Cureus 12:e6973. https:\/\/doi.org\/10.7759\/cureus.6973","journal-title":"Cureus"},{"key":"5595_CR24","doi-asserted-by":"publisher","first-page":"e187","DOI":"10.1016\/j.ijrobp.2012.10.030","volume":"85","author":"TE Merchant","year":"2013","unstructured":"Merchant TE, Kun LE, Hua CH, Wu S, Xiong X, Sanford RA, Boop FA (2013) Disease control after reduced volume conformal and intensity modulated radiation therapy for childhood craniopharyngioma. Int J Radiat Oncol Biol Phys 85:e187\u2013192. https:\/\/doi.org\/10.1016\/j.ijrobp.2012.10.030","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"5595_CR25","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.1002\/pbc.22884","volume":"56","author":"KM Winkfield","year":"2011","unstructured":"Winkfield KM, Tsai HK, Yao X, Larson E, Neuberg D, Pomeroy SL, Ullrich NJ, Cohen LE, Kieran MW, Scott RM, Goumnerova LC, Marcus KJ (2011) Long-term clinical outcomes following treatment of childhood craniopharyngioma. Pediatr Blood Cancer 56:1120\u20131126. https:\/\/doi.org\/10.1002\/pbc.22884","journal-title":"Pediatr Blood Cancer"},{"key":"5595_CR26","doi-asserted-by":"publisher","unstructured":"Indelicato DJ, Bradley JA, Sandler ES, Aldana PR, Sapp A, Gains JE, Crellin A, Rotondo RL (2017) Clinical outcomes following proton therapy for children with central nervous system tumors referred overseas. Pediatr Blood Cancer 64. https:\/\/doi.org\/10.1002\/pbc.26654","DOI":"10.1002\/pbc.26654"},{"key":"5595_CR27","doi-asserted-by":"publisher","first-page":"1480","DOI":"10.1016\/j.ijrobp.2021.02.045","volume":"110","author":"RB Jimenez","year":"2021","unstructured":"Jimenez RB, Ahmed S, Johnson A, Thomas H, Depauw N, Horick N, Tansky J, Evans CL, Pulsifer M, Ebb D, Butler WE, Fullerton B, Tarbell NJ, Yock TI, MacDonald SM (2021) Proton Radiation Therapy for Pediatric Craniopharyngioma. Int J Radiat Oncol Biol Phys 110:1480\u20131487. https:\/\/doi.org\/10.1016\/j.ijrobp.2021.02.045","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"5595_CR28","doi-asserted-by":"publisher","first-page":"103837","DOI":"10.1016\/j.clon.2025.103837","volume":"42","author":"M Bischoff","year":"2025","unstructured":"Bischoff M, Beckhaus J, Khalil DA, Sen F, Frisch S, Koska B, Kiewert C, Bison B, Kortmann RD, Friedrich C, Muller HL, Timmermann B (2025) Neuroendocrine Deficits and Weight Development Before and After Proton Therapy in Children With Craniopharyngioma. Clin Oncol (R Coll Radiol) 42:103837. https:\/\/doi.org\/10.1016\/j.clon.2025.103837","journal-title":"Clin Oncol (R Coll Radiol)"},{"key":"5595_CR29","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/s11060-024-04914-w","volume":"172","author":"Y Miao","year":"2025","unstructured":"Miao Y, Wu D, Li Y, Ji Y, Sang Y (2025) Radiation therapy for childhood-onset craniopharyngioma: systematic review and meta-analysis. J Neurooncol 172:89\u201398. https:\/\/doi.org\/10.1007\/s11060-024-04914-w","journal-title":"J Neurooncol"}],"container-title":["Journal of Neuro-Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11060-026-05595-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11060-026-05595-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11060-026-05595-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T07:59:38Z","timestamp":1779782378000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11060-026-05595-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["5595"],"URL":"https:\/\/doi.org\/10.1007\/s11060-026-05595-3","relation":{},"ISSN":["0167-594X","1573-7373"],"issn-type":[{"value":"0167-594X","type":"print"},{"value":"1573-7373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"25 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"146"}}