{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T08:14:39Z","timestamp":1788250479511,"version":"build-2803163510"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurooncol"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1007\/s11060-026-05733-x","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T16:32:36Z","timestamp":1785861156000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Longitudinal connectomics-based tractometry for characterizing white matter reorganization following brain tumor surgery: a proof-of-concept case series"],"prefix":"10.1007","volume":"179","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0032-5310","authenticated-orcid":false,"given":"Shoaib A.","family":"Syed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatimah M.","family":"Coppin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Latzman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching-Ling","family":"Teng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyar","family":"Bahadir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I\u00f1igo L.","family":"Sistiaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Schulder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3047-945X","authenticated-orcid":false,"given":"Randy S.","family":"D\u2019Amico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,4]]},"reference":[{"key":"5733_CR1","doi-asserted-by":"publisher","first-page":"2365063","DOI":"10.1155\/2016\/2365063","volume":"2016","author":"NW Kong","year":"2016","unstructured":"Kong NW, Gibb WR, Tate MC (2016) Neuroplasticity: Insights from Patients Harboring Gliomas. Neural Plast 2016:2365063. https:\/\/doi.org\/10.1155\/2016\/2365063","journal-title":"Neural Plast"},{"key":"5733_CR2","doi-asserted-by":"publisher","first-page":"711646","DOI":"10.3389\/fneur.2021.711646","volume":"12","author":"NB Dadario","year":"2021","unstructured":"Dadario NB, Brahimaj B, Yeung J, Sughrue ME (2021) Reducing the Cognitive Footprint of Brain Tumor Surgery. Front Neurol 12:711646 Published 2021 Aug 16. https:\/\/doi.org\/10.3389\/fneur.2021.711646","journal-title":"Front Neurol"},{"issue":"4","key":"5733_CR3","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1016\/j.ijrobp.2023.12.053","volume":"119","author":"J Sheehan","year":"2024","unstructured":"Sheehan J, Trifiletti D, Keole S (2024) Unlocking the Power of Connectomes for Image-Guided Cranial Interventions. Int J Radiat Oncol Biol Phys 119(4):1133\u20131136. https:\/\/doi.org\/10.1016\/j.ijrobp.2023.12.053","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"5733_CR4","doi-asserted-by":"publisher","unstructured":"Boerger TF, Pahapill P, Butts AM, Arocho-Quinones E, Raghavan M, Krucoff MO (2023) Large-scale brain networks and intra-axial tumor surgery: a narrative review of functional mapping techniques, critical needs, and scientific opportunities. Front Hum Neurosci 17:1170419. Published 2023 Jul 13. https:\/\/doi.org\/10.3389\/fnhum.2023.1170419","DOI":"10.3389\/fnhum.2023.1170419"},{"key":"5733_CR5","doi-asserted-by":"publisher","first-page":"108760","DOI":"10.1016\/j.clineuro.2025.108760Shah","volume":"249","author":"HA Shah","year":"2025","unstructured":"Shah HA, Duehr J, Abramyan A et al (2025) Enhancing brain tumor surgery precision with multimodal connectome imaging: Structural and functional connectivity in language-dominant areas. Clin Neurol Neurosurg 249:108760. https:\/\/doi.org\/10.1016\/j.clineuro.2025.108760Shah","journal-title":"Clin Neurol Neurosurg"},{"issue":"2","key":"5733_CR6","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1007\/s11060-025-05383-5","volume":"176","author":"IL Sistiaga","year":"2025","unstructured":"Sistiaga IL, Chen J, Mittelman L et al (2025) Connectomics in brain tumor surgery: large-scale clinical feasibility and hypothesis-generating tractometry findings. J Neurooncol 176(2):129 Published 2025 Dec 19. https:\/\/doi.org\/10.1007\/s11060-025-05383-5","journal-title":"J Neurooncol"},{"key":"5733_CR7","doi-asserted-by":"publisher","first-page":"119391","DOI":"10.1016\/j.neuroimage.2022.119391Basile","volume":"258","author":"GA Basile","year":"2022","unstructured":"Basile GA, Bertino S, Nozais V et al (2022) White matter substrates of functional connectivity dynamics in the human brain. NeuroImage 258:119391. https:\/\/doi.org\/10.1016\/j.neuroimage.2022.119391Basile","journal-title":"NeuroImage"},{"issue":"20","key":"5733_CR8","doi-asserted-by":"publisher","first-page":"4524","DOI":"10.1093\/cercor\/bhab500","volume":"32","author":"DN Bullock","year":"2022","unstructured":"Bullock DN, Hayday EA, Grier MD, Tang W, Pestilli F, Heilbronner SR (2022) A taxonomy of the brain\u2019s white matter: twenty-one major tracts for the 21st century. Cereb Cortex 32(20):4524\u20134548. https:\/\/doi.org\/10.1093\/cercor\/bhab500","journal-title":"Cereb Cortex"},{"issue":"6","key":"5733_CR9","first-page":"1258","volume":"27","author":"M Lazar","year":"2006","unstructured":"Lazar M, Alexander AL, Thottakara PJ, Badie B, Field AS (2006) White matter reorganization after surgical resection of brain tumors and vascular malformations. AJNR Am J Neuroradiol 27(6):1258\u20131271","journal-title":"AJNR Am J Neuroradiol"},{"issue":"13","key":"5733_CR10","doi-asserted-by":"publisher","first-page":"3326","DOI":"10.3390\/cancers15133326","volume":"15","author":"AA Manan","year":"2023","unstructured":"Manan AA, Yahya NA, Taib NHM, Idris Z, Manan HA (2023) The Assessment of White Matter Integrity Alteration Pattern in Patients with Brain Tumor Utilizing Diffusion Tensor Imaging: A Systematic Review. Cancers (Basel) 15(13):3326. https:\/\/doi.org\/10.3390\/cancers15133326. Published 2023 Jun 24","journal-title":"Cancers (Basel)"},{"key":"5733_CR11","doi-asserted-by":"publisher","unstructured":"Correia MM, Newcombe VFJ, Williams GB (2011) Contrast-to-noise ratios for indices of anisotropy obtained from diffusion MRI: a study with standard clinical b-values at 3T. Neuroimage 57:1103\u20131115. https:\/\/doi.org\/10.1016\/j.neuroimage.2011.03.004 Correia","DOI":"10.1016\/j.neuroimage.2011.03.004"},{"issue":"7\u20138","key":"5733_CR12","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1002\/nbm.782","volume":"15","author":"C Beaulieu","year":"2002","unstructured":"Beaulieu C (2002) The basis of anisotropic water diffusion in the nervous system - a technical review. NMR Biomed 15(7\u20138):435\u2013455. https:\/\/doi.org\/10.1002\/nbm.782","journal-title":"NMR Biomed"},{"issue":"3","key":"5733_CR13","first-page":"356","volume":"25","author":"BJ Jellison","year":"2004","unstructured":"Jellison BJ, Field AS, Medow J, Lazar M, Salamat MS, Alexander AL (2004) Diffusion tensor imaging of cerebral white matter: a pictorial review of physics, fiber tract anatomy, and tumor imaging patterns. AJNR Am J Neuroradiol 25(3):356\u2013369","journal-title":"AJNR Am J Neuroradiol"},{"issue":"1","key":"5733_CR14","doi-asserted-by":"publisher","first-page":"18369","DOI":"10.1038\/s41598-020-75617-1","volume":"10","author":"F Zhai","year":"2020","unstructured":"Zhai F, Liu J, Su N et al (2020) Disrupted white matter integrity and network connectivity are related to poor motor performance. Sci Rep 10(1):18369 Published 2020 Oct 27. https:\/\/doi.org\/10.1038\/s41598-020-75617-1","journal-title":"Sci Rep"},{"issue":"5","key":"5733_CR15","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.tics.2017.03.003","volume":"21","author":"FG Hillary","year":"2017","unstructured":"Hillary FG, Grafman JH (2017) Injured Brains and Adaptive Networks: The Benefits and Costs of Hyperconnectivity. Trends Cogn Sci 21(5):385\u2013401. https:\/\/doi.org\/10.1016\/j.tics.2017.03.003","journal-title":"Trends Cogn Sci"},{"key":"5733_CR16","doi-asserted-by":"publisher","first-page":"102435","DOI":"10.1016\/j.nicl.2020.102435","volume":"28","author":"E Cargnelutti","year":"2020","unstructured":"Cargnelutti E, Ius T, Skrap M, Tomasino B (2020) What do we know about pre- and postoperative plasticity in patients with glioma? A review of neuroimaging and intraoperative mapping studies. Neuroimage Clin 28:102435. https:\/\/doi.org\/10.1016\/j.nicl.2020.102435","journal-title":"Neuroimage Clin"},{"key":"5733_CR17","doi-asserted-by":"publisher","first-page":"1992","DOI":"10.1007\/s11682-022-00669-y","volume":"16","author":"T Xu","year":"2022","unstructured":"Xu T, Chen F, Zhang L et al (2022) Study on the changes of Structural Covariance Network in post-traumatic stress disorder. Brain Imaging Behav 16:1992\u20132000. https:\/\/doi.org\/10.1007\/s11682-022-00669-y","journal-title":"Brain Imaging Behav"},{"issue":"9","key":"5733_CR18","doi-asserted-by":"publisher","first-page":"3072","DOI":"10.1093\/brain\/awaf151","volume":"148","author":"N Mongay-Ochoa","year":"2025","unstructured":"Mongay-Ochoa N, Gonzalez-Escamilla G, Fleischer V et al (2025) Structural covariance analysis for neurodegenerative and neuroinflammatory brain disorders. Brain 148(9):3072\u20133084. https:\/\/doi.org\/10.1093\/brain\/awaf151","journal-title":"Brain"},{"key":"5733_CR19","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/j.neuroimage.2017.12.060","volume":"171","author":"R Romero-Garcia","year":"2018","unstructured":"Romero-Garcia R, Whitaker KJ, V\u00e1\u0161a F et al (2018) Structural covariance networks are coupled to expression of genes enriched in supragranular layers of the human cortex. NeuroImage 171:256\u2013267. https:\/\/doi.org\/10.1016\/j.neuroimage.2017.12.060","journal-title":"NeuroImage"},{"issue":"3","key":"5733_CR20","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1093\/cercor\/bhn102","volume":"19","author":"G Gong","year":"2009","unstructured":"Gong G, He Y, Concha L et al (2009) Mapping anatomical connectivity patterns of human cerebral cortex using in vivo diffusion tensor imaging tractography. Cereb Cortex 19(3):524\u2013536. https:\/\/doi.org\/10.1093\/cercor\/bhn102","journal-title":"Cereb Cortex"},{"issue":"5","key":"5733_CR21","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1038\/nrn3465","volume":"14","author":"A Alexander-Bloch","year":"2013","unstructured":"Alexander-Bloch A, Giedd JN, Bullmore E (2013) Imaging structural co-variance between human brain regions. Nat Rev Neurosci 14(5):322\u2013336","journal-title":"Nat Rev Neurosci"},{"key":"5733_CR22","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1007\/s11060-026-05578-4","volume":"177","author":"L Mittelman","year":"2026","unstructured":"Mittelman L, Sistiaga IL, Seenarine N et al (2026) Connectome-guided resection of deep-seated brain tumors using tubular retractors: matched cohort outcomes and exploratory quantitative tractometry. J Neurooncol 177:109. https:\/\/doi.org\/10.1007\/s11060-026-05578-4","journal-title":"J Neurooncol"},{"issue":"6","key":"5733_CR23","doi-asserted-by":"publisher","first-page":"e306","DOI":"10.1227\/ons.0000000000000239","volume":"22","author":"AJ Dicpinigaitis","year":"2022","unstructured":"Dicpinigaitis AJ, Feldstein E, Gandhi CD, Hanft S (2022) Letter: Early Experience Using Omniscient Neurotechnology Fiber Tracking Software for Resection of Intra-Axial Brain Tumors. Oper Neurosurg 22(6):e306\u2013e308. https:\/\/doi.org\/10.1227\/ons.0000000000000239","journal-title":"Oper Neurosurg"},{"issue":"suppl1","key":"5733_CR24","doi-asserted-by":"publisher","first-page":"S436","DOI":"10.1093\/ons\/opy267","volume":"15","author":"AK Conner","year":"2018","unstructured":"Conner AK, Briggs RG, Sali G et al (2018) A Connectomic Atlas of the Human Cerebrum-Chap. 13: Tractographic Description of the Inferior Fronto-Occipital Fasciculus. Oper Neurosurg 15(suppl1):S436\u2013S443. https:\/\/doi.org\/10.1093\/ons\/opy267","journal-title":"Oper Neurosurg"},{"key":"5733_CR25","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.dcn.2015.06.003","volume":"14","author":"IR Olson","year":"2015","unstructured":"Olson IR, Von Der Heide RJ, Alm KH, Vyas G (2015) Development of the uncinate fasciculus: Implications for theory and developmental disorders. Dev Cogn Neurosci 14:50\u201361. https:\/\/doi.org\/10.1016\/j.dcn.2015.06.003","journal-title":"Dev Cogn Neurosci"},{"key":"5733_CR26","doi-asserted-by":"publisher","first-page":"672665","DOI":"10.3389\/fnhum.2021.672665","volume":"15","author":"MV Ivanova","year":"2021","unstructured":"Ivanova MV, Zhong A, Turken A, Baldo JV, Dronkers NF (2021) Functional Contributions of the Arcuate Fasciculus to Language Processing. Front Hum Neurosci 15:672665 Published 2021 Jun 25. https:\/\/doi.org\/10.3389\/fnhum.2021.672665","journal-title":"Front Hum Neurosci"},{"key":"5733_CR27","doi-asserted-by":"publisher","unstructured":"Herbet G, Maheu M, Costi E, Lafargue G, Duffau H (2016) Mapping neuroplastic potential in brain-damaged patients. Brain 139:829\u2013844. https:\/\/doi.org\/10.1093\/brain\/awv394","DOI":"10.1093\/brain\/awv394"},{"issue":"8","key":"5733_CR28","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1016\/S1474-4422(05)70140-X","volume":"4","author":"H Duffau","year":"2005","unstructured":"Duffau H (2005) Lessons from brain mapping in surgery for low-grade glioma: insights into associations between tumour and brain plasticity. Lancet Neurol 4(8):476\u2013486. https:\/\/doi.org\/10.1016\/S1474-4422(05)70140-X","journal-title":"Lancet Neurol"},{"issue":"5","key":"5733_CR29","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1177\/1971400917720829","volume":"30","author":"G Silva","year":"2017","unstructured":"Silva G, Citterio A (2017) Hemispheric asymmetries in dorsal language pathway white-matter tracts: A magnetic resonance imaging tractography and functional magnetic resonance imaging study. Neuroradiol J 30(5):470\u2013476. https:\/\/doi.org\/10.1177\/1971400917720829","journal-title":"Neuroradiol J"},{"key":"5733_CR30","doi-asserted-by":"publisher","unstructured":"Castellanos NP, Bajo R, Cuesta P et al (2011) Alteration and reorganization of functional networks: a new perspective in brain injury study. Front Hum Neurosci 5:90. Published 2011 Sep 21. https:\/\/doi.org\/10.3389\/fnhum.2011.00090","DOI":"10.3389\/fnhum.2011.00090"},{"issue":"11","key":"5733_CR31","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.3390\/brainsci15111217","volume":"15","author":"JA Kuipers","year":"2025","unstructured":"Kuipers JA, Hoffman NH, Carrick FR, Jemni M (2025) Reconnecting Brain Networks After Stroke: A Scoping Review of Conventional, Neuromodulatory, and Feedback-Driven Rehabilitation Approaches. Brain Sci 15(11):1217. https:\/\/doi.org\/10.3390\/brainsci15111217","journal-title":"Brain Sci"},{"issue":"13","key":"5733_CR32","doi-asserted-by":"publisher","first-page":"2174","DOI":"10.3390\/cancers17132174","volume":"17","author":"PS Mart\u00ednez Lozada","year":"2025","unstructured":"Mart\u00ednez Lozada PS, Pozo Neira J, Leon-Rojas JE (2025) From Tumor to Network: Functional Connectome Heterogeneity and Alterations in Brain Tumors\u2014A Multimodal Neuroimaging Narrative Review. Cancers 17(13):2174. https:\/\/doi.org\/10.3390\/cancers17132174","journal-title":"Cancers"},{"key":"5733_CR33","doi-asserted-by":"publisher","first-page":"100307","DOI":"10.1016\/j.ynirp.2025.100307","volume":"6","author":"K Bullens","year":"2026","unstructured":"Bullens K, Sleurs C, Blommaert J et al (2026) Altered structural networks and cognitive functioning in long-term survivors of pediatric brain tumors. Neuroimage Rep 6:100307","journal-title":"Neuroimage Rep"},{"issue":"1","key":"5733_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1162\/netn_a_00339","volume":"8","author":"CJ Stam","year":"2024","unstructured":"Stam CJ (2024) Hub overload and failure as a final common pathway in neurological brain network disorders. Netw Neurosci 8(1):1\u201323 Published 2024 Apr 1. https:\/\/doi.org\/10.1162\/netn_a_00339","journal-title":"Netw Neurosci"},{"issue":"1","key":"5733_CR35","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1038\/nrneurol.2016.185","volume":"13","author":"MT Makale","year":"2017","unstructured":"Makale MT, McDonald CR, Hattangadi-Gluth JA, Kesari S (2017) Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours. Nat Rev Neurol 13(1):52\u201364. https:\/\/doi.org\/10.1038\/nrneurol.2016.185","journal-title":"Nat Rev Neurol"}],"container-title":["Journal of Neuro-Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11060-026-05733-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11060-026-05733-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11060-026-05733-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T07:27:03Z","timestamp":1788247623000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11060-026-05733-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["5733"],"URL":"https:\/\/doi.org\/10.1007\/s11060-026-05733-x","relation":{},"ISSN":["0167-594X","1573-7373"],"issn-type":[{"value":"0167-594X","type":"print"},{"value":"1573-7373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"21 June 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 July 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 August 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This retrospective case series was performed under institutional review board approval (IRB# 21-0008). This study followed principles outlined in the Declaration of Helsinki and the Preferred Reporting of Case Series in Surgery (PROCESS) 2023 guidelines. All patients provided written informed consent for surgical intervention and imaging studies.","order":1,"name":"Ethics","label":"Human ethics and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"28"}}