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There is a paucity of literature examining what patients require expedited versus elective surgery. This single-center retrospective study describes complications, utilization, and survival by pathway.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Adults with WHO grade 3\u20134 gliomas undergoing primary resection (2021\u20132026) were classified as urgent (admitted without a planned resection date) or scheduled (discharged and readmitted for planned surgery, or managed exclusively as an outpatient). Primary outcomes were 30-day complications and days alive at home within 30 days of admission for resection (DAH-30). Secondary outcomes were progression free and overall survival. Survival was analyzed with propensity-score overlap weighting and Cox regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 166 patients, 122 underwent urgent resection and 44 scheduled resections; 40 of 44 (91%) proceeded as planned. Urgent patients more often had midline shift (62% vs. 32%), less often seizure (15% vs. 39%), and lower Karnofsky scores (70 vs. 80); all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009\u2264\u20090.002. They had longer index hospitalizations (median 8 vs. 3 days,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and fewer days at home (median 15 vs. 27; adjusted difference\u2009\u2212\u20098.9 days, 95% CI\u2009\u2212\u200912.9 to \u2212\u20094.8). Complication rates (36% vs. 30%; adjusted OR 1.15, 95% CI 0.52\u20132.62) and overall survival (median 15.4 vs. 19.0 months,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.758) did not differ detectably.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Scheduled resection identified a distinct population, recognizable at initial evaluation by preserved performance status and the absence of midline shift. These patients spent more days at home and required shorter hospitalizations; no harm signal was observed. These data suggest that a substantial proportion of patients with newly diagnosed presumed high grade gliomas can be managed effectively in an expedited, outpatient basis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s11060-026-05841-8","type":"journal-article","created":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T13:01:09Z","timestamp":1792674069000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Urgent versus scheduled resection in high-grade glioma: patient selection and healthcare utilization in a single-center cohort"],"prefix":"10.1007","volume":"180","author":[{"given":"Danny A.","family":"Mahmoudi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trent","family":"Kite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail","family":"McKenna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sami","family":"Shaikh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Praveer S.","family":"Vyas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Herbst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney E.","family":"Wegner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Karlovits","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander C.","family":"Whiting","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"Shepard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,22]]},"reference":[{"key":"5841_CR1","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1093\/neuonc\/noab106","volume":"23","author":"DN Louis","year":"2021","unstructured":"Louis DN, Perry A, Wesseling P et al (2021) The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. 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Figure\u00a0\n                      \n                      \u00a0C reports the four scheduled-crossover patients individually; the values shown were reviewed to ensure that potentially identifying detail was sufficiently limited, and the Institutional Review Board waiver covers their publication.","order":3,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study is reported in accordance with the STROBE statement for observational research.","order":4,"name":"Ethics","label":"Reporting guideline","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"M.J.S is a consultant for GT Medical Technologies Inc.","order":5,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"29"}}