{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T12:33:47Z","timestamp":1766493227635},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2006,10,6]],"date-time":"2006-10-06T00:00:00Z","timestamp":1160092800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurochem Res"],"published-print":{"date-parts":[[2006,11,2]]},"DOI":"10.1007\/s11064-006-9171-2","type":"journal-article","created":{"date-parts":[[2006,10,5]],"date-time":"2006-10-05T18:39:29Z","timestamp":1160073569000},"page":"1191-1196","source":"Crossref","is-referenced-by-count":7,"title":["Down-regulation of Phospholipase D2 mRNA in Neonatal Rat Brainstem and Cerebellum after Hypoxia-Ischemia"],"prefix":"10.1007","volume":"31","author":[{"given":"Jeng-Hsiung F.","family":"Peng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yangzheng","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip G.","family":"Rhodes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2006,10,6]]},"reference":[{"key":"9171_CR1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0169-328X(94)00217-3","volume":"29","author":"EJ Beiharz","year":"1995","unstructured":"Beiharz EJ, Williams CE, Dragunow M, Sirimanne ES, Gluckman PD (1995) Mechanisms of delayed cell death following hypoxic-ischemic injury in immature rat: evidence for apoptosis during selective neuronal loss. Mol Brain Res 29:1\u201314","journal-title":"Mol Brain Res"},{"key":"9171_CR2","doi-asserted-by":"crossref","first-page":"26159","DOI":"10.1074\/jbc.272.42.26159","volume":"272","author":"DJ Bratton","year":"1997","unstructured":"Bratton DJ, Fadok VA, Richter DA, Kailey JM, Guthrie LA, Henson PM (1997) Appearance of phosphatidylserine on apoptotic cells requires calcium- mediated non-specific flip\u2013flop and is enhanced by loss of the aminophospholipid translocase. J Biol Chem 272:26159\u201326165","journal-title":"J Biol Chem"},{"issue":"5","key":"9171_CR3","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.1152\/japplphysiol.00630.2003","volume":"95","author":"JW Calvert","year":"2003","unstructured":"Calvert JW, Zhou C, Nanda A, Zhang JH (2003) Effect of hyperbaric oxygen on apoptosis in neonatal hypoxia-ischemia rat model. J Appl Physiol 95(5):2072\u20132080","journal-title":"J Appl Physiol"},{"key":"9171_CR4","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1161\/01.CIR.94.7.1713","volume":"94","author":"MV Cohen","year":"1996","unstructured":"Cohen MV, Liu Y, Liu GS, Wang P, Weinbrenner C, Cordis GA, Das DK, Downey JM (1996) Phospholipase D plays a role in ischemic preconditioning in rabbit heart. Circulation 94:1713\u20131718","journal-title":"Circulation"},{"key":"9171_CR5","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S1388-1981(02)00328-1","volume":"1585","author":"Z Cui","year":"2002","unstructured":"Cui Z, Houweling M (2002) Phosphatidylcholine and cell death. Biochim Biophys Acta 1585:87\u201396","journal-title":"Biochim Biophys Acta"},{"issue":"2","key":"9171_CR6","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0014-4886(87)90138-5","volume":"95","author":"BE Dwyer","year":"1987","unstructured":"Dwyer BE, Nishimura RN, Powell CL, Mailheau SL (1987) Focal protein synthesis inhibition in a model of neonatal hypoxic-ischemic brain. Exp Neurol 95(2):277\u2013289","journal-title":"Exp Neurol"},{"key":"9171_CR7","first-page":"789","volume":"1","author":"DA Foster","year":"2003","unstructured":"Foster DA, Xu L (2003) Phospholipase D in cell proliferation and cancer. Mol Cancer Res 1:789\u2013800","journal-title":"Mol Cancer Res"},{"issue":"17","key":"9171_CR8","doi-asserted-by":"crossref","first-page":"5035","DOI":"10.1016\/j.bmc.2005.04.071","volume":"13","author":"RG Hanshaw","year":"2005","unstructured":"Hanshaw RG, Smith BD (2005) New reagents for phosphatidylserine recognition and detection of apoptosis. Bioorg Med Chem 13(17):5035\u20135042","journal-title":"Bioorg Med Chem"},{"key":"9171_CR9","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/0006-8993(95)00145-G","volume":"676","author":"IE Hill","year":"1995","unstructured":"Hill IE, MacManus JP, Rasquinha I, Tuor UI (1995) DNA fragmentation indicative of apoptosis following unilateral cerebral hypoxia-ischemia in the neonatal rat. Brain Res 676:398\u2013403","journal-title":"Brain Res"},{"issue":"1\u20132","key":"9171_CR10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0014-5793(00)01707-5","volume":"477","author":"VE Kagan","year":"2000","unstructured":"Kagan VE, Fabisiak JP, Shvedova AA, Tyurina YY, Schor NF, Kawai K (2000) Oxidative signaling pathway for externalization of plasma membrane phosphatidylserine during apoptosis. FEBS Lett 477(1\u20132):1\u20137","journal-title":"FEBS Lett"},{"issue":"5","key":"9171_CR11","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1203\/01.pdr.0000214891.35363.6a","volume":"59","author":"MJ Lafemina","year":"2006","unstructured":"Lafemina MJ, Sheldon RA, Ferriero DM (2006) Acute hypoxia-ischemia results in hydrogen peroxide accumulation in neonatal but not adult mouse brain. Pediatr Res 59(5):680\u2013683","journal-title":"Pediatr Res"},{"key":"9171_CR12","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0014-2999(99)00933-4","volume":"390","author":"MH LeBlanc","year":"2000","unstructured":"LeBlanc MH, Feng YZ, Fratkin JD (2000) TPCK pretreatment reduces hypoxic-ischemic brain injury in the newborn rat. Eur J Pharmacol 390:249\u2013256","journal-title":"Eur J Pharmacol"},{"key":"9171_CR13","first-page":"1","volume":"36","author":"S Levine","year":"1960","unstructured":"Levine S (1960) Anoxic-ischemic encephalopathy in rats. Am J Pathol 36:1\u201317","journal-title":"Am J Pathol"},{"key":"9171_CR14","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0022-510X(98)00036-7","volume":"156","author":"Y Li","year":"1998","unstructured":"Li Y, Powers C, Jiang N, Chopp M (1998) Intact, injured, necrotic and apoptotic cells after focal cerebral ischemia in the rat. J Neurol Sci 156:119\u2013132","journal-title":"J Neurol Sci"},{"issue":"5","key":"9171_CR15","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.cmet.2006.03.007","volume":"3","author":"Z Li","year":"2006","unstructured":"Li Z, Agellon LB, Allen TM, Umeda M, Jewell L, Mason A, Vance DE (2006) The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis. Cell Metab 3(5):321\u2013331","journal-title":"Cell Metab"},{"issue":"2","key":"9171_CR16","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1212\/WNL.54.2.362","volume":"54","author":"O Miyamoto","year":"2000","unstructured":"Miyamoto O, Auer RN (2000) Hypoxia, hyperoxia, ischemia, and brain necrosis. Neurology 54(2):362\u2013371","journal-title":"Neurology"},{"issue":"1\u20132","key":"9171_CR17","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0009-3084(99)00027-4","volume":"98","author":"S Nakashima","year":"1999","unstructured":"Nakashima S, Nozawa Y (1999) Possible role of phospholipase D in differentiation and apoptosis. Chem Phys Lipids 98(1\u20132):153\u2013164","journal-title":"Chem Phys Lipids"},{"key":"9171_CR18","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1161\/01.STR.25.6.1247","volume":"25","author":"A Nishida","year":"1994","unstructured":"Nishida A, Emoto K, Shimizu M, Uozumi T, Yamawaki S (1994) Brain ischemia decreases phosphatidylcholine-phospholipase D but not phosphatidylinositol-phospholipase C in rats. Stroke 25:1247\u20131251","journal-title":"Stroke"},{"key":"9171_CR19","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s12094-012-0758-6","volume":"14","author":"H Oshimoto","year":"2003","unstructured":"Oshimoto H, Okamura S, Yoshida M, Mori M (2003) Increased activity and expression of phopholipase D2 in colorectal cancer. Oncol Res 14:31\u201337","journal-title":"Oncol Res"},{"key":"9171_CR20","first-page":"584","volume":"18","author":"JH Peng","year":"2000","unstructured":"Peng JH, Rhodes PG (2000) Developmental expression of phopholipase D2 mRNA in rat brain. Int J Dev Neurosci 18:584\u2013589","journal-title":"Int J Dev Neurosci"},{"key":"9171_CR21","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.devbrainres.2005.02.002","volume":"156","author":"JH Peng","year":"2005","unstructured":"Peng JH, Feng YZ, LeBlanc MH, Rhodes PG, Parker JC (2005) Apoptosis and necrosis in developing cerebellum and brainstem induced after focal cerebral hypoxia-ischemia injury. Dev Brain Res 156:87\u201392","journal-title":"Dev Brain Res"},{"issue":"14","key":"9171_CR22","doi-asserted-by":"crossref","first-page":"3103","DOI":"10.1097\/00001756-200009280-00013","volume":"11","author":"B Ramos","year":"2000","unstructured":"Ramos B, Salido GM, Campo ML, Claro E (2000) Inhibition of phosphatidylcholine synthesis precedes apoptosis induced by C2-ceramide: protection by exogenous phosphatidylcholine. Neuroreport 11(14):3103\u20133108","journal-title":"Neuroreport"},{"issue":"6","key":"9171_CR23","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1002\/cbf.1252","volume":"23","author":"C Rauch","year":"2005","unstructured":"Rauch C, Loughna PT (2005) Inward relocation of exogenous phosphatidylserine triggered by IGF-1 in non-apoptotic C2C12 cells is concentration dependent. Cell Biochem Funct 2005. 23(6):383\u2013388","journal-title":"Cell Biochem Funct 2005."},{"issue":"2","key":"9171_CR24","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/ana.410090206","volume":"9","author":"JE Rice III","year":"1981","unstructured":"Rice JE III, Vanucci RC, Brierley JB (1981) The influence of immunity on hypoxic-ischemic brain damage in the rat. Ann Neurol 9(2):131\u2013141","journal-title":"Ann Neurol"},{"key":"9171_CR25","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0165-3806(99)00189-3","volume":"120","author":"S Saito","year":"2000","unstructured":"Saito S, Sakagami H, Kondo H (2000) Localization of mRNAs for phospholipase D types 1 and 2 in the brain of developing and mature rat. Dev Brain Res 120:41\u201347","journal-title":"Dev Brain Res"},{"issue":"18","key":"9171_CR26","doi-asserted-by":"crossref","first-page":"8286","DOI":"10.1158\/0008-5472.CAN-04-1913","volume":"65","author":"F Sandra","year":"2005","unstructured":"Sandra F, Degli Esposti M, Ndebele K, Gona P, knight D, Rosenquist M, Khostavi-Far R (2005) Tumor necrosis factor-related apoptosis-inducing ligand alters mitochondrial membrane lipids. Cancer Res 65(18):8286\u20138297","journal-title":"Cancer Res"},{"issue":"19","key":"9171_CR27","doi-asserted-by":"crossref","first-page":"5056","DOI":"10.1111\/j.1742-4658.2005.04914.x","volume":"272","author":"MM Taylor","year":"2005","unstructured":"Taylor MM, MacDonald K, Morris AJ, McMaster CR (2005) Enhanced apoptosis through farnesol inhibition of phospholipase D signal transduction. FEBS J 272(19):5056\u20135063","journal-title":"FEBS J"},{"issue":"1","key":"9171_CR28","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0361-9230(98)00144-0","volume":"48","author":"UI Tuor","year":"1999","unstructured":"Tuor UI, Manley JJ, Fyfe C (1999) Dexamethasone effects on cerebral protein synthesis prior to and following hypoxia-ischemia in immature rat. Brain Res Bull 48(1):61\u201364","journal-title":"Brain Res Bull"},{"key":"9171_CR29","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1089\/152308604322899288","volume":"6","author":"YY Tyurina","year":"2004","unstructured":"Tyurina YY, Kawai K, Tyurin VA, Liu SX, Kagan VE, Fabisiak JP (2004) The plasma membrane is the site of selective phosphatidylserine oxidation during apoptosis: role of cytochrome C. Antioxid Redox Signal 6:209\u2013225","journal-title":"Antioxid Redox Signal"},{"key":"9171_CR30","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1023\/A:1009650917818","volume":"3","author":"SM Vabdeneijinde","year":"1998","unstructured":"Vabdeneijinde SM, Boshart L, Baehrecke EH, Dezeeuw CI, Reutelingsberger CPM, Vermeijkeers C (1998) Cell surface exposure of phosphatidylserine during apoptosis is phylogenetically conserved. Apoptosis 3:9\u201316","journal-title":"Apoptosis"},{"key":"9171_CR31","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1203\/00006450-199004000-00001","volume":"27","author":"RC Vannucci","year":"1994","unstructured":"Vannucci RC (1994) Experimental biology of cerebral hypoxia-ischemia: relation to perinatal brain damage. Pediatr Res 27:317\u2013326","journal-title":"Pediatr Res"},{"key":"9171_CR32","doi-asserted-by":"crossref","first-page":"3871","DOI":"10.1097\/00001756-199712220-00007","volume":"8","author":"M Walton","year":"1997","unstructured":"Walton M, Sirimanne E, Reutelingsberger C, Williams C, Gluckman P, Drafunow M (1997) Annexin labels apoptotic neurons following hypoxia- ischemia. Neuroreport 8:3871\u20133875","journal-title":"Neuroreport"},{"key":"9171_CR33","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1139\/o03-092","volume":"82","author":"MM Wright","year":"2004","unstructured":"Wright MM, Howe AG, Zaremberg V (2004) Cell membranes and apoptosis: role of cardiolipin, phosphatidylcholine, and anticancer lipid analogues. Biochem Cell Biol 82:18\u201326","journal-title":"Biochem Cell Biol"},{"issue":"23","key":"9171_CR34","doi-asserted-by":"crossref","first-page":"15862","DOI":"10.1074\/jbc.M600660200","volume":"281","author":"Y Zheng","year":"2006","unstructured":"Zheng Y, Rodrik V, Toschi A, Shi M, Hui L, Shen Y, Foster DA (2006) Phospholipase D couples survival and migration signals in stress response of human cancer cells. J Biol Chem 281(23):15862\u201315868","journal-title":"J Biol Chem"},{"key":"9171_CR35","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1046\/j.1471-4159.2000.0750819.x","volume":"75","author":"C Zhu","year":"2000","unstructured":"Zhu C, Wang X, Hagberg H, Blomgren K (2000) Correlation between caspase-3 activation and three different markers of DNA damage in neonatal cerebral hypoxia-ischemia. J Neurochem 75:819\u2013829","journal-title":"J Neurochem"},{"issue":"2","key":"9171_CR36","doi-asserted-by":"crossref","first-page":"R273","DOI":"10.1152\/ajpregu.00160.2003","volume":"286","author":"A Zovein","year":"2004","unstructured":"Zovein A, Flowers-Ziegler J, Thamotharan S, Shin D, Sankar R, Nguyen K, Gambhir S, Devaskar SU (2004) Postnatal hypoxic-ischemic brain injury alters mechanisms mediating neuronal glucose transport. Am J Physiol Regul Integr Comp Physiol 286(2):R273\u2013R282","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"9171_CR37","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1084\/jem.20032100","volume":"200","author":"J Zweigner","year":"2004","unstructured":"Zweigner J, Jackowski S, Smith SH, Van Der Merwe M, Weber JR, Tuomanen EI (2004) Bacterial inhibition of phosphatidylcholine synthesis triggers apoptosis in the brain. J Exp Med 200:99\u2013106","journal-title":"J Exp Med"}],"container-title":["Neurochemical Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11064-006-9171-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11064-006-9171-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11064-006-9171-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T04:34:25Z","timestamp":1559363665000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11064-006-9171-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,6]]},"references-count":37,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2006,11,2]]}},"alternative-id":["9171"],"URL":"https:\/\/doi.org\/10.1007\/s11064-006-9171-2","relation":{},"ISSN":["0364-3190","1573-6903"],"issn-type":[{"value":"0364-3190","type":"print"},{"value":"1573-6903","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,6]]}}}