{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T22:40:37Z","timestamp":1792017637222,"version":"4.4.0"},"reference-count":56,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2013,2,22]],"date-time":"2013-02-22T00:00:00Z","timestamp":1361491200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurochem Res"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1007\/s11064-013-1005-4","type":"journal-article","created":{"date-parts":[[2013,2,21]],"date-time":"2013-02-21T07:28:57Z","timestamp":1361431737000},"page":"972-980","source":"Crossref","is-referenced-by-count":105,"title":["Neuroprotective Role of Withania somnifera Root Extract in Maneb\u2013Paraquat Induced Mouse Model of Parkinsonism"],"prefix":"10.1007","volume":"38","author":[{"given":"Jay","family":"Prakash","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satyndra Kumar","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shikha","family":"Chouhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Surya Pratap","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,2,22]]},"reference":[{"key":"1005_CR1","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/S0896-6273(03)00568-3","volume":"39","author":"W Dauer","year":"2003","unstructured":"Dauer W, Przedborski S (2003) Parkinson\u2019s disease: mechanisms and models. Neuron 39:889\u2013909","journal-title":"Neuron"},{"key":"1005_CR2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4061\/2011\/617472","volume":"2011","author":"RB Mounsey","year":"2010","unstructured":"Mounsey RB, Teismann P (2010) Mitochondrial dysfunction in Parkinson\u2019s disease pathogenesis and neuroprotection. Parkinsons Dis 2011:1\u201318","journal-title":"Parkinsons Dis"},{"key":"1005_CR3","first-page":"2","volume":"4","author":"S Fahn","year":"2000","unstructured":"Fahn S (2000) The spectrum of levodopa-induced dyskinesias. Ann Neurol 4:2\u201311","journal-title":"Ann Neurol"},{"key":"1005_CR4","first-page":"69","volume":"43","author":"MP Singh","year":"2006","unstructured":"Singh MP, Patel S, Dikshit M, Gupta YK (2006) Contribution of genomics and proteomics in understanding the role of modifying factors in Parkinson\u2019s disease. Indian J Biochem Biophys 43:69\u201381","journal-title":"Indian J Biochem Biophys"},{"key":"1005_CR5","first-page":"19","volume":"53","author":"C Singh","year":"2007","unstructured":"Singh C, Ahmad I, Kumar A (2007) Pesticides and metals induced Parkinson\u2019s disease: involvement of free radicals and oxidative stress. Cell Mol Biol 53:19\u201328","journal-title":"Cell Mol Biol"},{"key":"1005_CR6","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0006-8993(00)02496-3","volume":"873","author":"M Thiruchelvam","year":"2000","unstructured":"Thiruchelvam M, Brockel BJ, Richfield EK, Baggs RB, Cory-Slechta DA (2000) Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: environmental risk factors for Parkinson\u2019s disease? Brain Res 873:225\u2013234","journal-title":"Brain Res"},{"key":"1005_CR7","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1289\/ehp.7570","volume":"113","author":"DA Cory-Slechta","year":"2005","unstructured":"Cory-Slechta DA, Thiruchelvam M, Barlow BK, Richfield EK (2005) Developmental pesticide models of the Parkinson disease phenotype. Environ Health Perspect 113:1263\u20131270","journal-title":"Environ Health Perspect"},{"key":"1005_CR8","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.brainres.2006.01.060","volume":"1081","author":"S Patel","year":"2006","unstructured":"Patel S, Singh V, Kumar A, Gupta YK, Singh MP (2006) Status of antioxidant defense system and expression of toxicant responsive genes in striatum of maneb-and paraquat-induced Parkinson\u2019s disease phenotype in mouse: mechanism of neurodegeneration. Brain Res 1081:9\u201318","journal-title":"Brain Res"},{"key":"1005_CR9","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s00441-004-0937-z","volume":"318","author":"VN Uversky","year":"2004","unstructured":"Uversky VN (2004) Neurotoxicant-induced animal models of Parkinson\u2019s disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration. Cell Tissue Res 318:225\u2013241","journal-title":"Cell Tissue Res"},{"key":"1005_CR10","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s00441-004-0938-y","volume":"318","author":"S Andreas","year":"2004","unstructured":"Andreas S (2004) Classic toxin-induced animal models of Parkinson\u2019s disease: 6-OHDA and MPTP. Cell Tissue Res 318:215\u2013224","journal-title":"Cell Tissue Res"},{"key":"1005_CR11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4061\/2011\/658083","volume":"2011","author":"JA Potashkin","year":"2011","unstructured":"Potashkin JA, Blume SR, Runkle NK (2011) Limitations of animal models of Parkinson\u2019s. Parkinsons Dis 2011:1\u20137","journal-title":"Parkinsons Dis"},{"key":"1005_CR12","first-page":"1","volume":"829","author":"S Yadav","year":"2012","unstructured":"Yadav S, Dixit A, Agrawal S, Singh A, Srivastava G, Singh AK, Srivastava PK, Prakash O, Singh MP (2012) Rodent models and contemporary molecular techniques: notable feats yet incomplete explanations of Parkinson\u2019s disease pathogenesis. Mol Neurobiol 829:1\u20138","journal-title":"Mol Neurobiol"},{"key":"1005_CR13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2202-10-88","volume":"10","author":"M Somayajulu-Ni\u0163u","year":"2009","unstructured":"Somayajulu-Ni\u0163u M, Sandhu JK, Cohen J, Sikorska M, Sridhar TS, Matei A, Borowy-Borowski H, Pandey S (2009) Paraquat induces oxidative stress, neuronal loss in substantia nigra region and parkinsonism in adult rats: neuroprotection and amelioration of symptoms by water soluble formulation of coenzyme Q10. BMC Neurosci 10:1\u201312","journal-title":"BMC Neurosci"},{"key":"1005_CR14","first-page":"336","volume":"84","author":"J Zhang","year":"2003","unstructured":"Zhang J, Fitsanakis VA, Gu G, Jing D, Ao M, Amarnath V, Montine TJ (2003) Manganese ethylene-bis-dithiocarbamate and selective dopaminergic neurodegeneration in rat: a link through mitochondrial dysfunction. J Neuro-chem 84:336\u2013346","journal-title":"J Neuro-chem"},{"key":"1005_CR15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0006-8993(98)01192-5","volume":"823","author":"AI Brooks","year":"1999","unstructured":"Brooks AI, Chadwick CA, Gelbard HA, Cory-Slechta DA, Federoff HJ (1999) Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss. Brain Res 823:1\u201310","journal-title":"Brain Res"},{"key":"1005_CR16","doi-asserted-by":"crossref","first-page":"9207","DOI":"10.1523\/JNEUROSCI.20-24-09207.2000","volume":"20","author":"M Thiruchelvam","year":"2000","unstructured":"Thiruchelvam M, Richfield EK, Baggs RB, Tank AW, Cory-Slechta DA (2000) The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implica-tions for Parkinson\u2019s disease. J Neurosci 20:9207\u20139214","journal-title":"J Neurosci"},{"key":"1005_CR17","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1007\/s11064-010-0176-5","volume":"35","author":"SP Gupta","year":"2010","unstructured":"Gupta SP, Patel S, Yadav S, Singh AK, Singh S, Singh MP (2010) Involvement of nitric oxide in maneb and paraquat-induced Parkinson\u2019s disease phenotype in mouse: is there any link with lipid peroxidation? Neurochem Res 35:1206\u20131213","journal-title":"Neurochem Res"},{"key":"1005_CR18","first-page":"334","volume":"5","author":"LC Mishra","year":"2000","unstructured":"Mishra LC, Singh BB, Dagenais S (2000) Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev 5:334\u2013346","journal-title":"Altern Med Rev"},{"key":"1005_CR19","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1309\/XLNDTE289WAQYK0Y","volume":"121","author":"SMH Sadrzadeh","year":"2004","unstructured":"Sadrzadeh SMH, Saffari Y (2004) Iron and brain disorders. Am J Clin Pathol 121:64\u201370","journal-title":"Am J Clin Pathol"},{"key":"1005_CR20","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/0166-2236(85)90010-4","volume":"8","author":"B Halliwell","year":"1985","unstructured":"Halliwell B, Gutteridge JMC (1985) Oxygen radicals and the nervous system. Trends Neurosci 8:22\u201329","journal-title":"Trends Neurosci"},{"key":"1005_CR21","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0378-4274(98)00399-3","volume":"105","author":"M Kale","year":"1999","unstructured":"Kale M, Rathore N, John S, Bhatnagar D (1999) Lipid peroxidative damage on pyrethroid exposure and alterations in antioxidant status in rat erythrocytes: a possible involvement of reactive oxygen species. Toxicol Lett 105:197\u2013205","journal-title":"Toxicol Lett"},{"key":"1005_CR22","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/S0022-510X(00)00329-4","volume":"176","author":"N Nagashayana","year":"2000","unstructured":"Nagashayana N, Sankarankutty P, Nampoothiri MR, Mohan PK, Mohanakumar KP (2000) Association of L-DOPA with recovery following ayurveda medication in Parkinson\u2019s disease. J Neurol Sci 176:124\u2013127","journal-title":"J Neurol Sci"},{"key":"1005_CR23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0027265","volume":"6","author":"A Konar","year":"2011","unstructured":"Konar A, Shah N, Singh R, Saxena N, Kaul SC, Wadhwa R, Thakur MK (2011) Protective role of Ashwagandha leaf extract and its component with an one on scopolamine-induced changes in the brain and brain-derived cells. PLoS One 6:1\u201311","journal-title":"PLoS One"},{"key":"1005_CR24","doi-asserted-by":"crossref","first-page":"10608","DOI":"10.3390\/ijms130810608","volume":"13","author":"S Koppula","year":"2012","unstructured":"Koppula S, Kumar H, More SV, Kim BW, Kim IS, Choi DK (2012) Recent advances on the neuroprotective potential of antioxidants in experimental models of Parkinson\u2019s disease. Int J Mol Sci 13:10608\u201310629","journal-title":"Int J Mol Sci"},{"key":"1005_CR25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-8741(00)00309-3","volume":"74","author":"A Bhattacharya","year":"2001","unstructured":"Bhattacharya A, Ghosal S, Bhattacharya SK (2001) Anti-oxidant effect of Withania somnifera glycowithanolides in chronic footshock stress-induced perturbations of oxidative free radical scavenging enzymes and lipid peroxidation in rat frontal cortex and striatum. J Ethnopharmacol 74:1\u20136","journal-title":"J Ethnopharmacol"},{"key":"1005_CR26","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0378-8741(94)01119-2","volume":"44","author":"A Grandhi","year":"1994","unstructured":"Grandhi A, Mujumdar AM, Patwardhan B (1994) A comparative pharmacological investigation of Ashwagandha and Ginseng. J Ethnopharmacol 44:13\u201315","journal-title":"J Ethnopharmacol"},{"key":"1005_CR27","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/j.pnpbp.2007.09.011","volume":"32","author":"SK Kulkarni","year":"2008","unstructured":"Kulkarni SK, Dhir A (2008) Withania somnifera: an Indian ginseng. Prog Neuro Pharmacol Biol Psychiatry 32:1093\u20131105","journal-title":"Prog Neuro Pharmacol Biol Psychiatry"},{"key":"1005_CR28","first-page":"1715","volume":"13","author":"T Kuboyama","year":"2002","unstructured":"Kuboyama T, Tohda C, Zhao J, Nakamura N, Hattori M, Komatsu K (2002) Axon or dendrite predominant outgrowth induced by constituents from Ashwagandha. Neuro Rep 13:1715\u20131720","journal-title":"Neuro Rep"},{"key":"1005_CR29","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1159\/000085384","volume":"14","author":"C Tohda","year":"2005","unstructured":"Tohda C, Kuboyama T, Komatsu K (2005) Search for natural products related to regeneration of the neuronal network. Neurosignals 14:34\u201345","journal-title":"Neurosignals"},{"key":"1005_CR30","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.neulet.2009.02.044","volume":"454","author":"S Rajasankar","year":"2009","unstructured":"Rajasankar S, Manivasagam T, Surendran S (2009) Ashwagandha leaf extract: a potential agent in treating oxidative damage and physiological abnormalities seen in a mouse model of Parkinson\u2019s disease. Neurosci Lett 454:11\u201315","journal-title":"Neurosci Lett"},{"key":"1005_CR31","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.jep.2009.08.003","volume":"125","author":"S Rajasankara","year":"2009","unstructured":"Rajasankara S, Manivasagam T, Sankar V, Prakash S, Muthusamy R, Krishnamurti A, Surendran S (2009) Withania somnifera root extract improves catecholamines and physiological abnormalities seen in a Parkinson\u2019s disease model mouse. J Ethnopharmacol 125:369\u2013373","journal-title":"J Ethnopharmacol"},{"key":"1005_CR32","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.devbrainres.2004.07.003","volume":"153","author":"S Surendran","year":"2004","unstructured":"Surendran S, Shihabuddin LS, Clarke J, Taksir TV, Stewart GR, Parsons G, Yang W, Tyring SK, Michals-Matalon K, Matalon R (2004) Mouse neural progenitor cells differentiate into oligodendrocytes in the brain of a knockout mouse model of Canavan disease. Brain Res Dev Brain Res 153:19\u201327","journal-title":"Brain Res Dev Brain Res"},{"key":"1005_CR33","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.jns.2006.06.018","volume":"249","author":"M Mohanasundari","year":"2006","unstructured":"Mohanasundari M, Srinivasan MS, Sethupathy S, Sabesan M (2006) Enhanced neuroprotective effect by combination of bromocriptine and Hypericum perforatum extract against MPTP-induced neurotoxicity in mice. J Neurol Sci 249:140\u2013144","journal-title":"J Neurol Sci"},{"key":"1005_CR34","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0278-5846(88)90038-3","volume":"12","author":"M Pisa","year":"1998","unstructured":"Pisa M (1998) Regional specialization of motor functions in the rat striatum: implications for the treatment of Parkinsonism. Prog Neuro Pharmacol Biol Psychiatry 12:217\u2013224","journal-title":"Prog Neuro Pharmacol Biol Psychiatry"},{"key":"1005_CR35","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0165-0270(02)00360-6","volume":"123","author":"JL Tillerson","year":"2003","unstructured":"Tillerson JL, Miller GW (2003) Grid performance test to measure behavioral impairment in the MPTP-treated-mouse model of parkinsonism. J Neurosci Methods 123:189\u2013200","journal-title":"J Neurosci Methods"},{"key":"1005_CR36","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","volume":"95","author":"H Ohkawa","year":"1979","unstructured":"Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351\u2013358","journal-title":"Anal Biochem"},{"key":"1005_CR37","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/S0076-6879(96)68016-1","volume":"268","author":"DL Granger","year":"1996","unstructured":"Granger DL, Taintor RR, Boockvar KS, Hibbs JB (1996) Measurement of nitrate and nitrite in biological samples using nitrate reductase and Greiss reaction. Methods Enzymol 268:142\u2013151","journal-title":"Methods Enzymol"},{"key":"1005_CR38","first-page":"389","volume":"47","author":"AK Sinha","year":"1972","unstructured":"Sinha AK (1972) Colorimetric assay of catalase. Anal Chem 47:389\u2013394","journal-title":"Anal Chem"},{"key":"1005_CR39","doi-asserted-by":"crossref","first-page":"950","DOI":"10.3109\/10715762.2010.492832","volume":"44","author":"A Kumar","year":"2010","unstructured":"Kumar A, Ahmad I, Shukla S, Singh BK, Patel DK, Pandey HP, Singh C (2010) Effect of zinc and paraquat co-exposure on neurodegeneration: modulation of oxidative stress and expression of metallothioneins, toxicant responsive and transporter genes in rats. Free Radic Res 44:950\u2013965","journal-title":"Free Radic Res"},{"key":"1005_CR40","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.neurobiolaging.2010.02.018","volume":"33","author":"AK Singh","year":"2012","unstructured":"Singh AK, Tiwari MN, Upadhyay G, Patel DK, Singh D, Prakash O, Singh MP (2012) Long-term exposure to cypermethrin induces nigrostriatal dopaminergic neurodegeneration in adult rats: postnatal exposure enhances the susceptibility during adulthood. Neurobiol Aging 33:404\u2013415","journal-title":"Neurobiol Aging"},{"key":"1005_CR41","doi-asserted-by":"crossref","first-page":"10918","DOI":"10.1073\/pnas.191107398","volume":"98","author":"H Mochizuki","year":"2001","unstructured":"Mochizuki H, Hayakawa H, Migita M, Shibata M, Tanaka R, Suzuki A, Shimo-Nakanishi Y, Urabe T, Yamada M, Tamayose K, Shimada T, Miura M, Mizuno Y (2001) An AAV-derived Apaf-1 dominant negative inhibitor prevents MPTP toxicity as antiapoptotic gene therapy for Parkinson\u2019s disease. Proc Natl Acad Sci USA 98:10918\u201310923","journal-title":"Proc Natl Acad Sci USA"},{"key":"1005_CR42","first-page":"502","volume":"6","author":"PM Kidd","year":"2000","unstructured":"Kidd PM (2000) Parkinson\u2019s disease as multifactorial oxidative neurodegeneration: implications for integrative management. Altern Med Rev 6:502\u2013529","journal-title":"Altern Med Rev"},{"key":"1005_CR43","first-page":"975","volume":"7","author":"S Rajasankar","year":"2007","unstructured":"Rajasankar S, Manivasagam T, Albert Singh T, Krishnamurti A, Ramanathan M (2007) Prophylactic effect of Withania somonifera against MPTP induced Parkin-son\u2019s disease in mice. Cell Tissue Res 7:975\u2013979","journal-title":"Cell Tissue Res"},{"key":"1005_CR44","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/0006-8993(91)90170-Z","volume":"554","author":"RK Schwarting","year":"1991","unstructured":"Schwarting RK, Bonatz AE, Carey RJ, Huston JP (1991) Relationships between indices of behavioral asymmetries and neurochemical changes following mesencephalic 6-hydroxydopamine injections. Brain Res 554:46\u201355","journal-title":"Brain Res"},{"key":"1005_CR45","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0165-0270(01)00485-X","volume":"113","author":"PO Fernagut","year":"2002","unstructured":"Fernagut PO, Diguet E, Labattu B, Tison F (2002) A simple method to measure stride length as an index of nigrostriatal dysfunction in mice. J Neurosci Methods 113:123\u2013130","journal-title":"J Neurosci Methods"},{"key":"1005_CR46","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1046\/j.1471-4159.2003.01531.x","volume":"84","author":"KS Zafar","year":"2003","unstructured":"Zafar KS, Sayeed I, Siddiqui A, Ahmad M, Salim S, Islam F (2003) Dose-dependent protective effect of selenium in partial lesion model of Parkinson\u2019s disease: neurobehavioral and neurochemical evidences. J Neurochem 84:438\u2013446","journal-title":"J Neurochem"},{"key":"1005_CR47","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1191\/0960327106ht635oa","volume":"25","author":"M Ahmad","year":"2006","unstructured":"Ahmad M, Yousuf S, Khan MB, Saleem S, Ishrat T, Hoda Md N, Islam F (2006) Protective effects of ethanolic extract of delphinium denudatumin a rat model of Parkinson\u2019s disease. Human Expt Toxicol 25:361\u2013368","journal-title":"Human Expt Toxicol"},{"key":"1005_CR48","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1111\/j.1471-4159.1989.tb07264.x","volume":"52","author":"DT Dexter","year":"1989","unstructured":"Dexter DT, Wells FR, Lees AJ, Agid F, Agid Y, Jenner P, Marsden CD (1989) Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson\u2019s disease. J Neurochem 52:1830\u20131836","journal-title":"J Neurochem"},{"key":"1005_CR49","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1002\/(SICI)1098-1136(199910)28:1<13::AID-GLIA2>3.0.CO;2-L","volume":"28","author":"H Noack","year":"1999","unstructured":"Noack H, Possel H, Rethfeldt C, Keilhoff G, Wolf G (1999) Peroxynitrite med-iated damage and lowered superoxide tolerance in primary cor-tical glial cultures after induction of the inducible isoform of NOS. Glia 28:13\u201324","journal-title":"Glia"},{"key":"1005_CR50","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.tox.2004.11.023","volume":"208","author":"A Denicola","year":"2005","unstructured":"Denicola A, Radi R (2005) Peroxynitrite and drug-dependent toxicity. Toxicology 208:273\u2013288","journal-title":"Toxicology"},{"key":"1005_CR51","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.tox.2004.11.033","volume":"208","author":"F Antunes","year":"2005","unstructured":"Antunes F, Nunes C, Laranjinha J, Cadenas E (2005) Redox interactions of nitric oxide with dopamine and its derivatives. Toxicology 208:207\u2013212","journal-title":"Toxicology"},{"key":"1005_CR52","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1089\/acm.2004.10.971","volume":"10","author":"GC Jagetia","year":"2004","unstructured":"Jagetia GC, Malagi KJ, Baliga MS, Venkatesh P, Veruva RR (2004) Triphala, an ayurvedic rasayana drug, protects mice against radiation-induced lethality by free-radical scavenging. J Altern Complement Med 10:971\u2013978","journal-title":"J Altern Complement Med"},{"key":"1005_CR53","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1007\/s11064-009-9987-7","volume":"34","author":"M Bhatnagar","year":"2009","unstructured":"Bhatnagar M, Sharma D, Salvi M (2009) Neuroprotective effects of Withania somnifera dunal.: a possible mechanism. Neurochem Res 34:1975\u20131983","journal-title":"Neurochem Res"},{"key":"1005_CR54","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1080\/10715760802513733","volume":"42","author":"I Ahmad","year":"2008","unstructured":"Ahmad I, Kumar A, Shukla S, Prasad Pandey H, Singh C (2008) The involvement of nitric oxide in maneb- and paraquat-induced oxidative stress in rat polymorphonuclear leukocytes. Free Radic Res 42:849\u2013862","journal-title":"Free Radic Res"},{"key":"1005_CR55","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1007\/s11064-011-0682-0","volume":"37","author":"S Yadav","year":"2011","unstructured":"Yadav S, Gupta SP, Srivastava G, Srivastava PK, Singh MP (2011) Role of secondary mediators in caffeine-mediated neuroprotection in maneb and paraquat induced Parkinson\u2019s disease phenotype in the mouse. Neurochem Res 37:875\u2013884","journal-title":"Neurochem Res"},{"key":"1005_CR56","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.neulet.2008.05.116","volume":"441","author":"Y Cheng","year":"2008","unstructured":"Cheng Y, He G, Mu X, Zhang T, Li X, Hu J, Xu B, Du G (2008) Neuroprotective effect of baicalein against MPTP neurotoxicity: behavioral, biochemical and immunohistochemical profile. Neurosci Lett 441:16\u201320","journal-title":"Neurosci Lett"}],"container-title":["Neurochemical Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11064-013-1005-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11064-013-1005-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11064-013-1005-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,10]],"date-time":"2019-07-10T00:06:09Z","timestamp":1562717169000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11064-013-1005-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,22]]},"references-count":56,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["1005"],"URL":"https:\/\/doi.org\/10.1007\/s11064-013-1005-4","relation":{},"ISSN":["0364-3190","1573-6903"],"issn-type":[{"value":"0364-3190","type":"print"},{"value":"1573-6903","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,22]]}}}