{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T09:26:26Z","timestamp":1774776386148,"version":"3.50.1"},"reference-count":63,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2015,5,6]],"date-time":"2015-05-06T00:00:00Z","timestamp":1430870400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2015,5,6]],"date-time":"2015-05-06T00:00:00Z","timestamp":1430870400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100004787","name":"The Research Council","doi-asserted-by":"publisher","award":["RC\/AGR\/FOOD\/11\/01"],"award-info":[{"award-number":["RC\/AGR\/FOOD\/11\/01"]}],"id":[{"id":"10.13039\/501100004787","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004351","name":"Sultan Qaboos University","doi-asserted-by":"publisher","award":["IG\/AGR\/FOOD\/14\/01"],"award-info":[{"award-number":["IG\/AGR\/FOOD\/14\/01"]}],"id":[{"id":"10.13039\/501100004351","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurochem Res"],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.1007\/s11064-015-1593-2","type":"journal-article","created":{"date-parts":[[2015,5,5]],"date-time":"2015-05-05T16:04:23Z","timestamp":1430841863000},"page":"1283-1293","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Dietary Supplementation of Walnut Partially Reverses 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Induced Neurodegeneration in a Mouse Model of Parkinson\u2019s Disease"],"prefix":"10.1007","volume":"40","author":[{"given":"Musthafa Mohamed","family":"Essa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selvaraju","family":"Subash","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chinnasamy","family":"Dhanalakshmi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thamilarasan","family":"Manivasagam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samir","family":"Al-Adawi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilles J.","family":"Guillemin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arokiasamy Justin","family":"Thenmozhi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,5,6]]},"reference":[{"key":"1593_CR1","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/S1474-4422(06)70471-9","volume":"5","author":"LM de Lau","year":"2006","unstructured":"de Lau LM, Breteler MM (2006) Epidemiology of Parkinson\u2019s disease. Lancet Neurol 5:525\u2013535","journal-title":"Lancet Neurol"},{"key":"1593_CR2","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1016\/S0896-6273(03)00568-3","volume":"39","author":"W Dauer","year":"2003","unstructured":"Dauer W, Przedborski S (2003) Parkinson\u2019s disease: mechanisms and models. Neuron 39:889\u2013909","journal-title":"Neuron"},{"key":"1593_CR3","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1007\/BF01291788","volume":"103","author":"M Gerlach","year":"1996","unstructured":"Gerlach M, Riederer P (1996) Animal models of Parkinson\u2019s disease: an empirical comparison with the phenomenology of the disease in man. J Neural Transm 103:987\u20131041","journal-title":"J Neural Transm"},{"key":"1593_CR4","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1007\/s007020100004","volume":"108","author":"N Schmidt","year":"2001","unstructured":"Schmidt N, Ferger B (2001) Neurochemical findings in the MPTP model of Parkinson\u2019s disease. J Neural Transm 108:1263\u20131282","journal-title":"J Neural Transm"},{"key":"1593_CR5","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1080\/01635580802065302","volume":"60","author":"WE Hardman","year":"2008","unstructured":"Hardman WE, Ion G (2008) Suppression of implanted MDA-MB231 human breast cancer growth in nude mice by dietary walnut. Nutr Cancer 60:666\u2013674","journal-title":"Nutr Cancer"},{"key":"1593_CR6","doi-asserted-by":"publisher","first-page":"4444","DOI":"10.1021\/jf8002174","volume":"56","author":"H Shimoda","year":"2008","unstructured":"Shimoda H, Tanaka J, Kikuchi M, Fukuda T, Ito H, Hatano T, Yoshida T (2008) Walnut polyphenols prevent liver damage induced by carbon tetrachloride and d-galactosamine: hepatoprotective hydrolyzable tannins in the kernel pellicles of walnut. J Agric Food Chem 56:4444\u20134449","journal-title":"J Agric Food Chem"},{"key":"1593_CR7","doi-asserted-by":"publisher","first-page":"2554","DOI":"10.1001\/jama.288.20.2554","volume":"288","author":"R Jiang","year":"2002","unstructured":"Jiang R, Manson JE, Stamfer MJ, Liu S, Willett WC, Hu FB (2002) Nut and pea nut butter consumption and risk of type 2 diabetes in women. JAMA 288:2554\u20132560","journal-title":"JAMA"},{"key":"1593_CR8","first-page":"683","volume":"13","author":"S Gandev","year":"2007","unstructured":"Gandev S (2007) Budding and grafting of the walnut (Juglans regia L.) and their effectiveness in Bulgaria. Bulg J Agric Sci 13:683\u2013689","journal-title":"Bulg J Agric Sci"},{"key":"1593_CR9","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1093\/jn\/130.2.171","volume":"130","author":"M Iwamoto","year":"2000","unstructured":"Iwamoto M, Sato M, Kono M, Hirooka Y, Saka K, Takeshita A, Imaizumi K (2000) Walnuts lower serum cholesterol in Japanese men and women. J Nutr 130:171\u2013176","journal-title":"J Nutr"},{"key":"1593_CR10","doi-asserted-by":"publisher","first-page":"1609","DOI":"10.1161\/01.CIR.0000124477.91474.FF","volume":"109","author":"E Ros","year":"2004","unstructured":"Ros E, Nnez I, Perez-Heras A, Merce S, Gilabert R, Casals E, Deulofeu R (2004) Walnut diet improves endothelial functions in hypercholesterolemic subject. Circulation 109:1609\u20131614","journal-title":"Circulation"},{"key":"1593_CR11","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/1475-2891-7-13","volume":"7","author":"KJ Spaccarotella","year":"2008","unstructured":"Spaccarotella KJ, Kris-Etherton PM, Stone WL, Bagshaw DM, Fishell VK, West SG, Lawrence FR, Hartman TJ (2008) The effect of walnut intake on factors related to prostate and vascular health in older men. Nutr J 7:13","journal-title":"Nutr J"},{"issue":"4","key":"1593_CR12","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.3233\/JAD-140675","volume":"42","author":"B Muthaiyah","year":"2014","unstructured":"Muthaiyah B, Essa MM, Lee M, Chauhan V, Kaur K, Chauhan A (2014) Dietary supplementation of walnut improves memory deficits and learning skills in mouse model of Alzheimer\u2019s disease. J Alzheimers Dis 42(4):1397\u20131405. doi: 10.3233\/JAD-140675","journal-title":"J Alzheimers Dis"},{"key":"1593_CR13","doi-asserted-by":"publisher","first-page":"4853","DOI":"10.1021\/jf0478354","volume":"53","author":"C Crews","year":"2005","unstructured":"Crews C, Hough P, Godward J, Brereton P, Lees M, Guiet S, Winkelmann W (2005) Study of the main constituents of some authentic walnut oils. J Agric Food Chem 53:4853\u20134860","journal-title":"J Agric Food Chem"},{"key":"1593_CR14","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/685909","author":"N Braidy","year":"2013","unstructured":"Braidy N, Subash S, Essa MM, Vaishnav R, Al-Adawi S, Al-Asmi A, Al-Senawi H, Alobaidy AAR, Lakhtakia R, Guillemin GJ (2013) Neuroprotective effects of a variety of pomegranate juice extracts (PJE) against MPTP-induced cytotoxicity and oxidative stress in human primary neurons. Oxid Med Cell Longev. doi: 10.1155\/2013\/685909","journal-title":"Oxid Med Cell Longev"},{"key":"1593_CR15","doi-asserted-by":"publisher","unstructured":"Maraldi M, Vauzour D, Angeloni C (2014) Dietary polyphenols and their effects on cell biochemistry and pathophysiology. Oxid Med Cell Longev 2014:576363. doi: 10.1155\/2014\/576363","DOI":"10.1155\/2014\/576363"},{"key":"1593_CR16","doi-asserted-by":"publisher","first-page":"2096","DOI":"10.1007\/s11064-011-0533-z","volume":"36","author":"B Muthaiyah","year":"2011","unstructured":"Muthaiyah B, Essa MM, Chauhan C, Chauhan V (2011) Protective effects of walnut extract against amyloid beta peptide-induced cell death and oxidative stress in PC12 cells. Neurochem Res 36:2096\u20132103","journal-title":"Neurochem Res"},{"issue":"3","key":"1593_CR17","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1159\/000354917","volume":"27","author":"G Park","year":"2014","unstructured":"Park G, Kim HG, Hong SP, Kim SY, Oh MS (2014) Walnuts (seeds of Juglandis sinensis L.) protect human epidermal keratinocytes against UVB-induced mitochondria-mediated apoptosis through upregulation of ROS elimination pathways. Skin Pharmacol Physiol 27(3):132\u2013140. doi: 10.1159\/000354917 Epub 2014 Jan 11","journal-title":"Skin Pharmacol Physiol"},{"key":"1593_CR18","unstructured":"International Union of Pure and Applied Chemistry (IUPAC) (1992) Standard methods for the analysis of oils, fats and derivatives (1st Suppl. to 7th ed., Enlarged ed.). Blackwell Scientific Publications, Oxford (Methods 2201, 2205, 2432, 2301, 2302, 2324, and 2507)"},{"key":"1593_CR19","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1002\/ejlt.201100039","volume":"113","author":"P Calvo","year":"2011","unstructured":"Calvo P, Casta\u00f1o \u00c1L, Hern\u00e1ndez MT, Gonz\u00e1lez-G\u00f3mez D (2011) Effects of microcapsule constitution into the quality of microencapsulated walnut oil. Eur J Lipid Sci Technol 113:1273\u20131280","journal-title":"Eur J Lipid Sci Technol"},{"key":"1593_CR20","doi-asserted-by":"publisher","first-page":"4898","DOI":"10.1021\/jf010321+","volume":"49","author":"S Burkhardt","year":"2001","unstructured":"Burkhardt S, Xian Tan D, Manchester LC, Hardeland R, Reiter RJ (2001) Detection and quantification of the antioxidant melatonin in Montmorency and Balaton tart cherries (Prunus cerasus). J Agric Food Chem 49:4898\u20134902","journal-title":"J Agric Food Chem"},{"key":"1593_CR21","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1016\/j.foodchem.2004.04.014","volume":"90","author":"VLAG Lima","year":"2005","unstructured":"Lima VLAG, M\u00e9lo EA, Maciel MIS, Prazeres FG, Musser RS, Lima DES (2005) Total phenolic and carotenoid content in acerola genotypes harvested at three ripening stages. Food Chem 90:565\u2013568","journal-title":"Food Chem"},{"key":"1593_CR22","doi-asserted-by":"crossref","first-page":"144","DOI":"10.5344\/ajev.1965.16.3.144","volume":"16","author":"VL Singleton","year":"1965","unstructured":"Singleton VL, Rossi JA Jr (1965) Colorimetry of total phenolics with phosphomolybdic phosphotungstic acid reagents. Am J Enol Vitic 16:144\u2013158","journal-title":"Am J Enol Vitic"},{"key":"1593_CR23","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1007\/s12640-009-9061-x","volume":"16","author":"N Schintu","year":"2009","unstructured":"Schintu N, Frau L, Ibba M, Garau A, Carboni E, Carta AR (2009) Progressive dopaminergic degeneration in the chronic MPTPp mouse model of Parkinson\u2019s disease. Neurotox Res 16:127\u2013139","journal-title":"Neurotox Res"},{"key":"1593_CR24","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1111\/j.1600-0773.1993.tb01345.x","volume":"72","author":"P Rojas","year":"1993","unstructured":"Rojas P, Rios C (1993) Increased striatal lipid peroxidation after inter cerbro ventricular MPP+ administration to mice. Pharmacol Toxicol 72:364\u2013368","journal-title":"Pharmacol Toxicol"},{"key":"1593_CR25","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.jns.2006.06.018","volume":"249","author":"M Mohanasundari","year":"2006","unstructured":"Mohanasundari M, Srinivasan MS, Sethupathy S, Sabesan M (2006) Enhanced neuroprotective effect by combination of bromocriptine and Hypericumperforatum extract against MPTP-induced neurotoxicity in mice. J Neurol Sci 249:140\u2013144","journal-title":"J Neurol Sci"},{"key":"1593_CR26","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.neulet.2009.02.044","volume":"454","author":"S Rajasankar","year":"2009","unstructured":"Rajasankar S, Manivasagam T, Surendran S (2009) Ashwagandha leaf extract: a potential agent in treating oxidative damage and physiological abnormalities seen in a mouse model of Parkinson\u2019s disease. Neurosci Lett 454:11\u201315","journal-title":"Neurosci Lett"},{"key":"1593_CR27","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/j.cbi.2013.09.016","volume":"206","author":"M Kavitha","year":"2013","unstructured":"Kavitha M, Nataraj J, Essa MM, Memon MA, Manivasagam T (2013) Mangiferin attenuates MPTP induced dopaminergic neurodegeneration and improves motor impairment, redox balance and Bcl-2\/Bax expression in experimental Parkinson\u2019s disease mice. Chem Biol Interact 206:239\u2013247","journal-title":"Chem Biol Interact"},{"key":"1593_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0378-8741(00)00309-3","volume":"74","author":"A Bhattacharya","year":"2001","unstructured":"Bhattacharya A, Ghosal S, Bhattacharya SK (2001) Antioxidant effect of Withania somnifera glycol withanolides in chronic foot-shock stress induced perturbations of oxidative free radical scavenging enzymes and lipid peroxidation in rat frontal cortex and striatum. J Ethnopharmacol 74:1\u201316","journal-title":"J Ethnopharmacol"},{"key":"1593_CR29","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1159\/000136485","volume":"11","author":"DJ Jollow","year":"1974","unstructured":"Jollow DJ, Mitchell JR, Zampaglione N, Gillette JR (1974) Bromobenzene induced liver necrosis: protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite. Pharmacology 11:151\u2013169","journal-title":"Pharmacology"},{"key":"1593_CR30","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0076-6879(84)05016-3","volume":"105","author":"H Aebi","year":"1984","unstructured":"Aebi H (1984) Catalase in vitro. Methods Enzymol 105:121\u2013126","journal-title":"Methods Enzymol"},{"key":"1593_CR31","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1006\/abbi.1993.1458","volume":"305","author":"Y Yamamoto","year":"1993","unstructured":"Yamamoto Y, Takahashi K (1993) Glutathione peroxidase isolated from plasma reduces phospholipid hydroperoxide. Arch Biochem Biophys 305:541\u2013545","journal-title":"Arch Biochem Biophys"},{"key":"1593_CR32","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S0076-6879(84)05064-3","volume":"105","author":"LW Oberley","year":"1984","unstructured":"Oberley LW, Spitz DR (1984) Assay of superoxide dismutase activity in tumor tissue. Methods Enzymol 105:457\u2013464","journal-title":"Methods Enzymol"},{"key":"1593_CR33","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1046\/j.1471-4159.1999.0731127.x","volume":"73","author":"SB Berman","year":"1999","unstructured":"Berman SB, Hastings TG (1999) Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson\u2019s disease. J Neurochem 73:1127\u20131137","journal-title":"J Neurochem"},{"key":"1593_CR34","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/0076-6879(67)10055-4","volume":"10","author":"TE King","year":"1967","unstructured":"King TE, Howard RL (1967) Preparations and properties of soluble NADH dehydrogenases from cardiac muscle. Methods Enzymol 10:275\u2013294","journal-title":"Methods Enzymol"},{"key":"1593_CR35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/neuro.24.003.2009","volume":"1","author":"G Patki","year":"2009","unstructured":"Patki G, Che Y, Lau Y (2009) Mitochondrial dysfunction in the striatum of aged chronic mouse model of Parkinson\u2019s disease. Front Aging Neurosci 1:1\u20139","journal-title":"Front Aging Neurosci"},{"key":"1593_CR36","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1007\/s00394-007-0647-x","volume":"46","author":"L Davis","year":"2007","unstructured":"Davis L, Stonehouse W, Loots DT, Mukuddem-Petersen J, van der Westhuizen F, Hanekom SJ, Jerling JC (2007) The effects of high walnut and cashew nut diets on the antioxidant status of subjects with metabolic syndrome. Eur J Nutr 46:155\u2013164","journal-title":"Eur J Nutr"},{"key":"1593_CR37","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1177\/107424849900400403","volume":"4","author":"D Li","year":"1999","unstructured":"Li D, Saldeen T, Romeo F, Mehta JL (1999) Relative effects of alpha- and gamma-tocopherol on low-density lipoprotein oxidation and superoxide dismutase and nitric oxide synthase activity and protein expression in rats. J Cardiovasc Pharmacol Ther 4:219\u2013226","journal-title":"J Cardiovasc Pharmacol Ther"},{"key":"1593_CR38","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.foodchem.2005.07.033","volume":"98","author":"M Kornsteiner","year":"2006","unstructured":"Kornsteiner M, Wagner KH, Elmadfa I (2006) Tocopherol and total phenolics in 10 different nut types. Food Chem 98:381\u2013387","journal-title":"Food Chem"},{"key":"1593_CR39","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1016\/j.nut.2005.02.005","volume":"21","author":"RJ Reiter","year":"2005","unstructured":"Reiter RJ, Manchester LC, Dun-xian Tan MD (2005) Melatonin in walnuts: influence on levels of melatonin and total antioxidant capacity of blood. Nutrition 21:920\u2013924","journal-title":"Nutrition"},{"issue":"1","key":"1593_CR40","doi-asserted-by":"crossref","first-page":"105","DOI":"10.3233\/JAD-2009-1127","volume":"18","author":"L Ji","year":"2009","unstructured":"Ji L, Chauhan A, Wegiel J, Essa MM, Chauhan V (2009) Gelsolin is proteolytically cleaved in the brains of individuals with Alzheimer\u2019s disease. J Alzheimers Dis 18(1):105\u2013111","journal-title":"J Alzheimers Dis"},{"key":"1593_CR41","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.neulet.2009.02.044","volume":"454","author":"S RajaSankar","year":"2009","unstructured":"RajaSankar S, Manivasagam T, Surendran S (2009) Ashwagandha leaf extract: a potential agent in treating oxidative damage and physiological abnormalities seen in a mouse model of Parkinson\u2019s disease. Neurosci Lett 454:11\u201315","journal-title":"Neurosci Lett"},{"key":"1593_CR42","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1016\/S0306-4522(96)00545-3","volume":"77","author":"NA Tatton","year":"1997","unstructured":"Tatton NA, Kish SJ (1997) In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining. Neuroscience 77:1037\u20131048","journal-title":"Neuroscience"},{"key":"1593_CR43","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1007\/s11011-013-9416-0","volume":"28","author":"GG Ortiz","year":"2013","unstructured":"Ortiz GG, Pacheco-Mois\u00e9s FP, G\u00f3mez-Rodr\u00edguez VM, Gonz\u00e1lez-Renovato ED, Torres-S\u00e1nchez ED, Ram\u00edrez-Anguiano AC (2013) Fish oil, melatonin and vitamin E attenuates midbrain cyclooxygenase-2 activity and oxidative stress after the administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Metab Brain Dis 28:705\u2013709","journal-title":"Metab Brain Dis"},{"key":"1593_CR44","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/j.neuint.2010.06.020","volume":"57","author":"HA Khan","year":"2010","unstructured":"Khan HA (2010) Selenium\u00a0partially reverses the depletion of striatal dopamine and its metabolites in\u00a0MPTP-treated C57BL mice. Neurochem Int 57:489\u2013491","journal-title":"Neurochem Int"},{"key":"1593_CR45","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1046\/j.0022-3042.2001.00676.x","volume":"80","author":"W Duan","year":"2002","unstructured":"Duan W, Ladenheim B, Cutler RG, Kruman II, Cadet JL, Mattson MP (2002) Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson\u2019s disease. J Neurochem 80:101\u2013110","journal-title":"J Neurochem"},{"key":"1593_CR46","doi-asserted-by":"publisher","first-page":"1401","DOI":"10.1016\/j.pnpbp.2009.07.018","volume":"33","author":"M Bousquet","year":"2009","unstructured":"Bousquet M, Gibrat C, Saint-Pierre M, Julien C, Calon F, Cicchetti F (2009) Modulation of brain-derived neurotrophic factor as a potential neuroprotective mechanism of action of omega-3 fatty acids in a parkinsonian animal model. Prog Neuropsychopharmacol Biol Psychiatry 33:1401\u20131408","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"1593_CR47","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.pbb.2013.01.017","volume":"104","author":"G Park","year":"2013","unstructured":"Park G, Park YJ, Yang HO, Oh MS (2013) Ropinirole protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity in mice via anti-apoptotic mechanism. Pharmacol Biochem Behav 104:163\u2013168","journal-title":"Pharmacol Biochem Behav"},{"key":"1593_CR48","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/S0166-4328(01)00309-6","volume":"125","author":"M Sedelis","year":"2001","unstructured":"Sedelis M, Schwarting RK, Huston JP (2001) Behavioral phenotyping of the MPTP mouse model of Parkinson\u2019s disease. Behav Brain Res 125:109\u2013125","journal-title":"Behav Brain Res"},{"key":"1593_CR49","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.brainres.2011.11.021","volume":"1433","author":"A Anandhan","year":"2012","unstructured":"Anandhan A, Tamilselvam K, Radhiga T, Rao S, Essa MM, Manivasagam T (2012) Theaflavin, a black tea polyphenol, protects nigral dopaminergic neurons against chronic MPTP\/probenecid induced Parkinson\u2019s disease. Brain Res 1433:104\u2013113","journal-title":"Brain Res"},{"key":"1593_CR50","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1007\/BF02260967","volume":"7","author":"A Fredriksson","year":"1994","unstructured":"Fredriksson A, Archer T (1994) MPTP-induced behavioural and biochemical deficits: a parametric analysis. J Neural Transm Park Dis Dement Sect 7:123\u2013132","journal-title":"J Neural Transm Park Dis Dement Sect"},{"key":"1593_CR51","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1126\/science.6610213","volume":"224","author":"RE Heikkila","year":"1984","unstructured":"Heikkila RE, Hess A, Duvoisin RC (1984) Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice. Science 224:1451\u20131453","journal-title":"Science"},{"key":"1593_CR52","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1038\/nrn1883","volume":"7","author":"MB Youdim","year":"2006","unstructured":"Youdim MB, Edmondson D, Tipton KF (2006) The therapeutic potential of monoamine oxidase inhibitors. Nat Rev Neurosci 7:295\u2013309","journal-title":"Nat Rev Neurosci"},{"key":"1593_CR53","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.neuint.2008.07.001","volume":"53","author":"G Petrosillo","year":"2008","unstructured":"Petrosillo G, Matera M, Casanova G, Ruggiero FM, Paradies G (2008) Mitochondrial dysfunction in rat brain with aging involvement of complex I, reactive oxygen species and cardiolipin. Neurochem Int 53:126\u2013131","journal-title":"Neurochem Int"},{"key":"1593_CR54","doi-asserted-by":"publisher","first-page":"2142","DOI":"10.1111\/j.1471-4159.1990.tb05809.x","volume":"55","author":"AHV Schapira","year":"1990","unstructured":"Schapira AHV, Mann VM, Cooper JM, Dexter D, Daniel SE, Jenner P, Clark JB, Marsden CD (1990) Anatomic and disease specificity of NADH CoQ, reductase (complex I) deficiency in Parkinson\u2019s disease. J Neurochem 55:2142\u20132145","journal-title":"J Neurochem"},{"key":"1593_CR55","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1096\/fasebj.12.10.905","volume":"12","author":"D Muralikrishnan","year":"1998","unstructured":"Muralikrishnan D, Mohanakumar KP (1998) Neuroprtotection by bromocriptine against 1-methy1 4-pheny1 1,2,3,6 tetrahydrophyridine induced neurotoxicity in mice. FASEB J 12:905\u2013912","journal-title":"FASEB J"},{"key":"1593_CR56","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1111\/j.1745-7254.2005.00019.x","volume":"26","author":"X Chen","year":"2005","unstructured":"Chen X, Zhou Y, Chen Y, Zhu Y, Fang F, Chen L (2005) Ginsenoside Rg1 reduces MPTP induced substantia nigra neuron loss by suppressing oxidative stress. Acta Pharmacol Sin 26:56\u201362","journal-title":"Acta Pharmacol Sin"},{"key":"1593_CR57","first-page":"157","volume":"10","author":"A Rajeswari","year":"2006","unstructured":"Rajeswari A (2006) Curcumin protects mouse brain from oxidative stress caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Eur Rev Med Pharmacol Sci 10:157\u2013161","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"1593_CR58","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1002\/ana.410360305","volume":"36","author":"J Sian","year":"1994","unstructured":"Sian J, Dexter DT, Lees AJ, Daniel S, Agid Y, Javoy-Agid F, Jenner P, Marsden CD (1994) Alterations in glutathione levels in Parkinson\u2019s disease and other neurodegenerative disorders affecting basal ganglia. Ann Neurol 36:348\u2013355","journal-title":"Ann Neurol"},{"key":"1593_CR59","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1093\/ajcn\/84.1.95","volume":"84","author":"BL Halvorsen","year":"2006","unstructured":"Halvorsen BL, Carlsen MH, Phillips KM, B\u00f8hn SK, Holte K, Jacobs DR Jr, Blomhoff R (2006) Content of redox-active compounds (ie, antioxidants) in foods consumed in the United States. Am J Clin Nutr 84:95\u2013135","journal-title":"Am J Clin Nutr"},{"key":"1593_CR60","doi-asserted-by":"publisher","first-page":"3316","DOI":"10.1016\/j.fct.2010.08.029","volume":"48","author":"N Mishra","year":"2010","unstructured":"Mishra N, Dubey A, Mishra R, Barik N (2010) Study on antioxidant activity of common dry fruits. Food Chem Toxicol 48:3316\u20133320","journal-title":"Food Chem Toxicol"},{"issue":"13","key":"1593_CR61","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/1475-2891-13-4","volume":"10","author":"EH Haddad","year":"2014","unstructured":"Haddad EH, Gaban-Chong N, Oda K, Sabat\u00e9 J (2014) Effect of a walnut meal on postprandial oxidative stress and antioxidants in healthy individuals. Nutr J 10(13):4","journal-title":"Nutr J"},{"key":"1593_CR62","first-page":"155","volume":"4","author":"M Asadi-Shekaari","year":"2012","unstructured":"Asadi-Shekaari M, Kalantaripour TP, Nejad FA, Namazian E, Eslami A (2012) The anticonvulsant and neuroprotective effects of walnuts on the neurons of rat brain cortex. Avicenna J Med Biotechnol 4:155\u2013158","journal-title":"Avicenna J Med Biotechnol"},{"key":"1593_CR63","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1179\/1476830512Y.0000000023","volume":"16","author":"AN Carey","year":"2013","unstructured":"Carey AN, Fisher DR, Joseph JA, Shukitt-Hale dB (2013) The ability of walnut extract and fatty acids to protect against the deleterious effects of oxidative stress and inflammation in hippocampal cells. Nutr Neurosci 16:13\u201320","journal-title":"Nutr Neurosci"}],"updated-by":[{"DOI":"10.1007\/s11064-019-02887-1","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2019,10,18]],"date-time":"2019-10-18T00:00:00Z","timestamp":1571356800000}}],"container-title":["Neurochemical Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11064-015-1593-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11064-015-1593-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11064-015-1593-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11064-015-1593-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T03:28:04Z","timestamp":1691638084000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11064-015-1593-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,6]]},"references-count":63,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["1593"],"URL":"https:\/\/doi.org\/10.1007\/s11064-015-1593-2","relation":{"correction":[{"id-type":"doi","id":"10.1007\/s11064-019-02887-1","asserted-by":"object"}]},"ISSN":["0364-3190","1573-6903"],"issn-type":[{"value":"0364-3190","type":"print"},{"value":"1573-6903","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,6]]},"assertion":[{"value":"3 February 2015","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 April 2015","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 April 2015","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 May 2015","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 October 2019","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The original version of this article unfortunately contains an error in Fig. 2a (4th image for walnut). This has been corrected by publishing this erratum.","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}}]}}