{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T04:01:23Z","timestamp":1780459283479,"version":"3.54.1"},"reference-count":151,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T00:00:00Z","timestamp":1686182400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T00:00:00Z","timestamp":1686182400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurochem Res"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1007\/s11064-023-03963-3","type":"journal-article","created":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T15:02:06Z","timestamp":1686236526000},"page":"2969-2982","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Novel Mechanisms of Perioperative Neurocognitive Disorders: Ferroptosis and Pyroptosis"],"prefix":"10.1007","volume":"48","author":[{"given":"Hang","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongmei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Te","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoqing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,6,8]]},"reference":[{"issue":"7","key":"3963_CR1","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1016\/j.jalz.2016.03.005","volume":"12","author":"SK Inouye","year":"2016","unstructured":"Inouye SK, Marcantonio ER, Kosar CM, Tommet D, Schmitt EM, Travison TG, Saczynski JS, Ngo LH, Alsop DC, Jones RN (2016) The short-term and long-term relationship between delirium and cognitive trajectory in older surgical patients. Alzheimers Dement 12(7):766\u2013775","journal-title":"Alzheimers Dement"},{"key":"3963_CR2","doi-asserted-by":"crossref","unstructured":"Daiello LA, Racine AM, Yun Gou R, Marcantonio ER, Xie Z, Kunze LJ, Vlassakov KV, Inouye SK, Jones RN, Alsop D, Travison T, Arnold S, Cooper Z, Dickerson B, Fong T, Metzger E, Pascual-Leone A, Schmitt EM, Shafi M, Cavallari M, Dai W, Dillon ST, McElhaney J, Guttmann C, Hshieh T, Kuchel G, Libermann T, Ngo L, Press D, Saczynski J, Vasunilashorn S, O'Connor M, Kimchi E, Strauss J, Wong B, Belkin M, Ayres D, Callery M, Pomposelli F, Wright J, Schermerhorn M, Abrantes T, Albuquerque A, Bertrand S, Brown A, Callahan A, D'Aquila M, Dowal S, Fox M, Gallagher J, Anna Gersten R, Hodara A, Helfand B, Inloes J, Kettell J, Kuczmarska A, Nee J, Nemeth E, Ochsner L, Palihnich K, Parisi K, Puelle M, Rastegar S, Vella M, Xu G, Bryan M, Guess J, Enghorn D, Gross A, Gou Y, Habtemariam D, Isaza I, Kosar C, Rockett C, Tommet D, Gruen T, Ross M, Tasker K, Gee J, Kolanowski A, Pisani M, de Rooij S, Rogers S, Studenski S, Stern Y, Whittemore A, Gottlieb G, Orav J, Sperling R, Group* SS (2019) Postoperative delirium and postoperative cognitive dysfunction: overlap and divergence. Anesthesiology 131(3):477\u2013491","DOI":"10.1097\/ALN.0000000000002729"},{"issue":"6884","key":"3963_CR3","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/S0140-6736(55)92689-1","volume":"269","author":"PD Bedford","year":"1955","unstructured":"Bedford PD (1955) Adverse cerebral effects of anaesthesia on old people. Lancet 269(6884):259\u2013263","journal-title":"Lancet"},{"key":"3963_CR4","doi-asserted-by":"crossref","unstructured":"Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG, Nomenclature Consensus Working G (2018) Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018. Br J Anaesth 121(5):1005\u20131012","DOI":"10.1016\/j.bja.2017.11.087"},{"key":"3963_CR5","doi-asserted-by":"crossref","unstructured":"Needham MJ, Webb CE, Bryden DC (2017) Postoperative cognitive dysfunction and dementia: what we need to know and do. Br J Anaesth 119(suppl_1):i115\u2013i125","DOI":"10.1093\/bja\/aex354"},{"key":"3963_CR6","doi-asserted-by":"publisher","first-page":"112","DOI":"10.3389\/fnagi.2015.00112","volume":"7","author":"G Androsova","year":"2015","unstructured":"Androsova G, Krause R, Winterer G, Schneider R (2015) Biomarkers of postoperative delirium and cognitive dysfunction. Front Aging Neurosci 7:112","journal-title":"Front Aging Neurosci"},{"issue":"2","key":"3963_CR7","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1097\/ALN.0000000000000958","volume":"124","author":"MS Avidan","year":"2016","unstructured":"Avidan MS, Evers AS (2016) The fallacy of persistent postoperative cognitive decline. Anesthesiology 124(2):255\u2013258","journal-title":"Anesthesiology"},{"key":"3963_CR8","doi-asserted-by":"publisher","first-page":"175628642211143","DOI":"10.1177\/17562864221114356","volume":"15","author":"X Yang","year":"2022","unstructured":"Yang X, Huang X, Li M, Jiang Y, Zhang H (2022) Identification of individuals at risk for postoperative cognitive dysfunction (POCD). Ther Adv Neurol Disord 15:17562864221114356","journal-title":"Ther Adv Neurol Disord"},{"key":"3963_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2019.110791","volume":"130","author":"X Lin","year":"2020","unstructured":"Lin X, Chen Y, Zhang P, Chen G, Zhou Y, Yu X (2020) The potential mechanism of postoperative cognitive dysfunction in older people. Exp Gerontol 130:110791","journal-title":"Exp Gerontol"},{"issue":"26","key":"3963_CR10","doi-asserted-by":"publisher","first-page":"11908","DOI":"10.7150\/thno.50616","volume":"10","author":"J Zhang","year":"2020","unstructured":"Zhang J, Zhu S, Jin P, Huang Y, Dai Q, Zhu Q, Wei P, Yang Z, Zhang L, Liu H, Xu G, Chen L, Gu E, Zhang Y, Wen L, Liu X (2020) Graphene oxide improves postoperative cognitive dysfunction by maximally alleviating amyloid beta burden in mice. Theranostics 10(26):11908\u201311920","journal-title":"Theranostics"},{"key":"3963_CR11","doi-asserted-by":"crossref","unstructured":"Peden CJ, Miller TR, Deiner SG, Eckenhoff RG, Fleisher LA, Members of the Perioperative Brain Health Expert P (2021) Improving perioperative brain health: an expert consensus review of key actions for the perioperative care team. Br J Anaesth 126(2):423\u2013432","DOI":"10.1016\/j.bja.2020.10.037"},{"issue":"5","key":"3963_CR12","doi-asserted-by":"publisher","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","volume":"149","author":"SJ Dixon","year":"2012","unstructured":"Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE, Patel DN, Bauer AJ, Cantley AM, Yang WS, Morrison B 3rd, Stockwell BR (2012) Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell 149(5):1060\u20131072","journal-title":"Cell"},{"issue":"2","key":"3963_CR13","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.cell.2017.09.021","volume":"171","author":"BR Stockwell","year":"2017","unstructured":"Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascon S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, Zhang DD (2017) Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease. Cell 171(2):273\u2013285","journal-title":"Cell"},{"issue":"2","key":"3963_CR14","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1038\/nrmicro2070","volume":"7","author":"T Bergsbaken","year":"2009","unstructured":"Bergsbaken T, Fink SL, Cookson BT (2009) Pyroptosis: host cell death and inflammation. Nat Rev Microbiol 7(2):99\u2013109","journal-title":"Nat Rev Microbiol"},{"issue":"11","key":"3963_CR15","doi-asserted-by":"publisher","first-page":"2453","DOI":"10.1084\/jem.20190545","volume":"216","author":"P Orning","year":"2019","unstructured":"Orning P, Lien E, Fitzgerald KA (2019) Gasdermins and their role in immunity and inflammation. J Exp Med 216(11):2453\u20132465","journal-title":"J Exp Med"},{"key":"3963_CR16","doi-asserted-by":"publisher","first-page":"68","DOI":"10.3389\/fncel.2020.00068","volume":"14","author":"Y Fang","year":"2020","unstructured":"Fang Y, Gao S, Wang X, Cao Y, Lu J, Chen S, Lenahan C, Zhang JH, Shao A, Zhang J (2020) Programmed cell deaths and potential crosstalk with blood-brain barrier dysfunction after hemorrhagic stroke. Front Cell Neurosci 14:68","journal-title":"Front Cell Neurosci"},{"issue":"15","key":"3963_CR17","doi-asserted-by":"publisher","first-page":"8363","DOI":"10.3390\/ijms23158363","volume":"23","author":"E Paldino","year":"2022","unstructured":"Paldino E, Fusco FR (2022) Emerging role of NLRP3 inflammasome\/pyroptosis in Huntington\u2019s disease. Int J Mol Sci 23(15):8363","journal-title":"Int J Mol Sci"},{"issue":"3","key":"3963_CR18","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1007\/s10571-022-01250-3","volume":"43","author":"R Atabaki","year":"2022","unstructured":"Atabaki R, Khaleghzadeh-Ahangar H, Esmaeili N, Mohseni-Moghaddam P (2022) Role of pyroptosis, a pro-inflammatory programmed cell death, in epilepsy. Cell Mol Neurobiol 43(3):1049\u20131059","journal-title":"Cell Mol Neurobiol"},{"issue":"7","key":"3963_CR19","doi-asserted-by":"publisher","first-page":"4880","DOI":"10.1007\/s12035-018-1403-3","volume":"56","author":"A Weiland","year":"2019","unstructured":"Weiland A, Wang Y, Wu W, Lan X, Han X, Li Q, Wang J (2019) Ferroptosis and its role in diverse brain diseases. Mol Neurobiol 56(7):4880\u20134893","journal-title":"Mol Neurobiol"},{"key":"3963_CR20","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1016\/j.intimp.2018.12.019","volume":"67","author":"S Wang","year":"2019","unstructured":"Wang S, Yuan YH, Chen NH, Wang HB (2019) The mechanisms of NLRP3 inflammasome\/pyroptosis activation and their role in Parkinson\u2019s disease. Int Immunopharmacol 67:458\u2013464","journal-title":"Int Immunopharmacol"},{"key":"3963_CR21","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2021.105640","volume":"169","author":"Y Wang","year":"2021","unstructured":"Wang Y, Guan X, Gao CL, Ruan W, Zhao S, Kai G, Li F, Pang T (2021) Medioresinol as a novel PGC-1alpha activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARalpha-GOT1 axis. Pharmacol Res 169:105640","journal-title":"Pharmacol Res"},{"key":"3963_CR22","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2022.889765","volume":"16","author":"X Chen","year":"2022","unstructured":"Chen X, Pang X, Yeo AJ, Xie S, Xiang M, Shi B, Yu G, Li C (2022) The molecular mechanisms of ferroptosis and its role in blood-brain barrier dysfunction. Front Cell Neurosci 16:889765","journal-title":"Front Cell Neurosci"},{"key":"3963_CR23","doi-asserted-by":"publisher","first-page":"4295208","DOI":"10.1155\/2022\/4295208","volume":"2022","author":"S Gao","year":"2022","unstructured":"Gao S, Zhou L, Lu J, Fang Y, Wu H, Xu W, Pan Y, Wang J, Wang X, Zhang J, Shao A (2022) Cepharanthine attenuates early brain injury after subarachnoid hemorrhage in mice via inhibiting 15-lipoxygenase-1-mediated microglia and endothelial cell ferroptosis. Oxid Med Cell Longev 2022:4295208","journal-title":"Oxid Med Cell Longev"},{"key":"3963_CR24","doi-asserted-by":"publisher","first-page":"175909142211332","DOI":"10.1177\/17590914221133236","volume":"14","author":"S Liu","year":"2022","unstructured":"Liu S, Gao X, Zhou S (2022) New target for prevention and treatment of neuroinflammation: microglia iron accumulation and ferroptosis. ASN Neuro 14:17590914221133236","journal-title":"ASN Neuro"},{"key":"3963_CR25","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2022.922331","volume":"16","author":"X Wu","year":"2022","unstructured":"Wu X, Wan T, Gao X, Fu M, Duan Y, Shen X, Guo W (2022) Microglia pyroptosis: a candidate target for neurological diseases treatment. Front Neurosci 16:922331","journal-title":"Front Neurosci"},{"issue":"1","key":"3963_CR26","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.tins.2019.11.005","volume":"43","author":"BA McKenzie","year":"2020","unstructured":"McKenzie BA, Dixit VM, Power C (2020) Fiery cell death: pyroptosis in the central nervous system. Trends Neurosci 43(1):55\u201373","journal-title":"Trends Neurosci"},{"issue":"1","key":"3963_CR27","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1186\/s12974-022-02570-3","volume":"19","author":"Y Song","year":"2022","unstructured":"Song Y, Wu Z, Xue H, Zhao P (2022) Ferroptosis is involved in regulating perioperative neurocognitive disorders: emerging perspectives. J Neuroinflammation 19(1):219","journal-title":"J Neuroinflammation"},{"issue":"1","key":"3963_CR28","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1038\/s41420-022-01068-4","volume":"8","author":"Z Wu","year":"2022","unstructured":"Wu Z, Tan J, Lin L, Zhang W, Yuan W (2022) microRNA-140-3p protects hippocampal neuron against pyroptosis to attenuate sevoflurane inhalation-induced post-operative cognitive dysfunction in rats via activation of HTR2A\/ERK\/Nrf2 axis by targeting DNMT1. Cell Death Discov 8(1):290","journal-title":"Cell Death Discov"},{"issue":"4","key":"3963_CR29","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1016\/j.molcel.2021.12.001","volume":"82","author":"R Rodriguez","year":"2022","unstructured":"Rodriguez R, Schreiber SL, Conrad M (2022) Persister cancer cells: Iron addiction and vulnerability to ferroptosis. Mol Cell 82(4):728\u2013740","journal-title":"Mol Cell"},{"issue":"22","key":"3963_CR30","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202100997","volume":"8","author":"X Yao","year":"2021","unstructured":"Yao X, Li W, Fang D, Xiao C, Wu X, Li M, Luo Z (2021) Emerging roles of energy metabolism in ferroptosis regulation of tumor cells. Adv Sci (Weinh) 8(22):e2100997","journal-title":"Adv Sci (Weinh)"},{"issue":"11","key":"3963_CR31","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.1164\/rccm.202106-1445OC","volume":"205","author":"E Diaz-Garcia","year":"2022","unstructured":"Diaz-Garcia E, Garcia-Tovar S, Alfaro E, Jaureguizar A, Casitas R, Sanchez-Sanchez B, Zamarron E, Fernandez-Lahera J, Lopez-Collazo E, Cubillos-Zapata C, Garcia-Rio F (2022) Inflammasome activation: a keystone of proinflammatory response in obstructive sleep apnea. Am J Respir Crit Care Med 205(11):1337\u20131348","journal-title":"Am J Respir Crit Care Med"},{"issue":"10","key":"3963_CR32","doi-asserted-by":"publisher","first-page":"2843","DOI":"10.1038\/s41418-021-00859-z","volume":"28","author":"X Chen","year":"2021","unstructured":"Chen X, Kang R, Kroemer G, Tang D (2021) Organelle-specific regulation of ferroptosis. Cell Death Differ 28(10):2843\u20132856","journal-title":"Cell Death Differ"},{"key":"3963_CR33","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.cytogfr.2022.01.006","volume":"64","author":"N Ebrahimi","year":"2022","unstructured":"Ebrahimi N, Adelian S, Shakerian S, Afshinpour M, Chaleshtori SR, Rostami N, Rezaei-Tazangi F, Beiranvand S, Hamblin MR, Aref AR (2022) Crosstalk between ferroptosis and the epithelial-mesenchymal transition: Implications for inflammation and cancer therapy. Cytokine Growth Factor Rev 64:33\u201345","journal-title":"Cytokine Growth Factor Rev"},{"key":"3963_CR34","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2022.811196","volume":"10","author":"Z Yang","year":"2022","unstructured":"Yang Z, Shi J, Chen L, Fu C, Shi D, Qu H (2022) Role of pyroptosis and ferroptosis in the progression of atherosclerotic plaques. Front Cell Dev Biol 10:811196","journal-title":"Front Cell Dev Biol"},{"issue":"3","key":"3963_CR35","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1038\/s41418-022-00941-0","volume":"29","author":"J Chen","year":"2022","unstructured":"Chen J, Li X, Ge C, Min J, Wang F (2022) The multifaceted role of ferroptosis in liver disease. Cell Death Differ 29(3):467\u2013480","journal-title":"Cell Death Differ"},{"issue":"1","key":"3963_CR36","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20211405","volume":"219","author":"S Bauernfried","year":"2022","unstructured":"Bauernfried S, Hornung V (2022) Human NLRP1: from the shadows to center stage. J Exp Med 219(1):e20211405","journal-title":"J Exp Med"},{"issue":"7521","key":"3963_CR37","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1038\/nature13683","volume":"514","author":"J Shi","year":"2014","unstructured":"Shi J, Zhao Y, Wang Y, Gao W, Ding J, Li P, Hu L, Shao F (2014) Inflammatory caspases are innate immune receptors for intracellular LPS. Nature 514(7521):187\u2013192","journal-title":"Nature"},{"issue":"7575","key":"3963_CR38","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1038\/nature15514","volume":"526","author":"J Shi","year":"2015","unstructured":"Shi J, Zhao Y, Wang K, Shi X, Wang Y, Huang H, Zhuang Y, Cai T, Wang F, Shao F (2015) Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Nature 526(7575):660\u2013665","journal-title":"Nature"},{"issue":"6418","key":"3963_CR39","doi-asserted-by":"publisher","first-page":"1064","DOI":"10.1126\/science.aau2818","volume":"362","author":"P Orning","year":"2018","unstructured":"Orning P, Weng D, Starheim K, Ratner D, Best Z, Lee B, Brooks A, Xia S, Wu H, Kelliher MA, Berger SB, Gough PJ, Bertin J, Proulx MM, Goguen JD, Kayagaki N, Fitzgerald KA, Lien E (2018) Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death. Science 362(6418):1064\u20131069","journal-title":"Science"},{"issue":"7799","key":"3963_CR40","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1038\/s41586-020-2071-9","volume":"579","author":"Z Zhang","year":"2020","unstructured":"Zhang Z, Zhang Y, Xia S, Kong Q, Li S, Liu X, Junqueira C, Meza-Sosa KF, Mok TMY, Ansara J, Sengupta S, Yao Y, Wu H, Lieberman J (2020) Gasdermin E suppresses tumour growth by activating anti-tumour immunity. Nature 579(7799):415\u2013420","journal-title":"Nature"},{"issue":"22","key":"3963_CR41","doi-asserted-by":"publisher","first-page":"4579","DOI":"10.1016\/j.molcel.2021.09.003","volume":"81","author":"J Hou","year":"2021","unstructured":"Hou J, Hsu JM, Hung MC (2021) Molecular mechanisms and functions of pyroptosis in inflammation and antitumor immunity. Mol Cell 81(22):4579\u20134590","journal-title":"Mol Cell"},{"key":"3963_CR42","doi-asserted-by":"crossref","unstructured":"Yan B, Ai Y, Sun Q, Ma Y, Cao Y, Wang J, Zhang Z, Wang X (2021) Membrane damage during ferroptosis is caused by oxidation of phospholipids catalyzed by the oxidoreductases POR and CYB5R1. Mol Cell 81(2):355\u2013369 e310","DOI":"10.1016\/j.molcel.2020.11.024"},{"issue":"3","key":"3963_CR43","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/j.chembiol.2008.02.010","volume":"15","author":"WS Yang","year":"2008","unstructured":"Yang WS, Stockwell BR (2008) Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells. Chem Biol 15(3):234\u2013245","journal-title":"Chem Biol"},{"issue":"4","key":"3963_CR44","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1016\/j.bbrc.2020.07.032","volume":"531","author":"Y Wang","year":"2020","unstructured":"Wang Y, Liu Y, Liu J, Kang R, Tang D (2020) NEDD4L-mediated LTF protein degradation limits ferroptosis. Biochem Biophys Res Commun 531(4):581\u2013587","journal-title":"Biochem Biophys Res Commun"},{"key":"3963_CR45","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.590226","volume":"8","author":"X Chen","year":"2020","unstructured":"Chen X, Yu C, Kang R, Tang D (2020) Iron metabolism in ferroptosis. Front Cell Dev Biol 8:590226","journal-title":"Front Cell Dev Biol"},{"issue":"14","key":"3963_CR46","doi-asserted-by":"publisher","first-page":"e00010-19","DOI":"10.1128\/MCB.00010-19","volume":"39","author":"M Fujimaki","year":"2019","unstructured":"Fujimaki M, Furuya N, Saiki S, Amo T, Imamichi Y, Hattori N (2019) Iron supply via NCOA4-mediated ferritin degradation maintains mitochondrial functions. Mol Cell Biol 39(14):e00010-19","journal-title":"Mol Cell Biol"},{"issue":"7","key":"3963_CR47","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1016\/j.tem.2021.04.010","volume":"32","author":"A Ajoolabady","year":"2021","unstructured":"Ajoolabady A, Aslkhodapasandhokmabad H, Libby P, Tuomilehto J, Lip GYH, Penninger JM, Richardson DR, Tang D, Zhou H, Wang S, Klionsky DJ, Kroemer G, Ren J (2021) Ferritinophagy and ferroptosis in the management of metabolic diseases. Trends Endocrinol Metab 32(7):444\u2013462","journal-title":"Trends Endocrinol Metab"},{"issue":"23","key":"3963_CR48","doi-asserted-by":"publisher","first-page":"2604","DOI":"10.1182\/blood.2020007971","volume":"136","author":"CC Philpott","year":"2020","unstructured":"Philpott CC (2020) Iron on the move: mobilizing liver iron via NCOA4. Blood 136(23):2604\u20132605","journal-title":"Blood"},{"issue":"9","key":"3963_CR49","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1038\/cr.2016.95","volume":"26","author":"M Gao","year":"2016","unstructured":"Gao M, Monian P, Pan Q, Zhang W, Xiang J, Jiang X (2016) Ferroptosis is an autophagic cell death process. Cell Res 26(9):1021\u20131032","journal-title":"Cell Res"},{"issue":"34","key":"3963_CR50","doi-asserted-by":"publisher","first-page":"E4966","DOI":"10.1073\/pnas.1603244113","volume":"113","author":"WS Yang","year":"2016","unstructured":"Yang WS, Kim KJ, Gaschler MM, Patel M, Shchepinov MS, Stockwell BR (2016) Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis. Proc Natl Acad Sci USA 113(34):E4966-4975","journal-title":"Proc Natl Acad Sci USA"},{"issue":"5","key":"3963_CR51","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1038\/s41556-019-0305-6","volume":"21","author":"B Chu","year":"2019","unstructured":"Chu B, Kon N, Chen D, Li T, Liu T, Jiang L, Song S, Tavana O, Gu W (2019) ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway. Nat Cell Biol 21(5):579\u2013591","journal-title":"Nat Cell Biol"},{"key":"3963_CR52","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2021.108840","volume":"703","author":"Y Saito","year":"2021","unstructured":"Saito Y (2021) Lipid peroxidation products as a mediator of toxicity and adaptive response\u2014the regulatory role of selenoprotein and vitamin E. Arch Biochem Biophys 703:108840","journal-title":"Arch Biochem Biophys"},{"issue":"23","key":"3963_CR53","doi-asserted-by":"publisher","first-page":"12757","DOI":"10.1021\/acs.chemrev.0c00761","volume":"120","author":"MK Foret","year":"2020","unstructured":"Foret MK, Lincoln R, Do Carmo S, Cuello AC, Cosa G (2020) Connecting the \u201cdots\u201d: from free radical lipid autoxidation to cell pathology and disease. Chem Rev 120(23):12757\u201312787","journal-title":"Chem Rev"},{"key":"3963_CR54","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.freeradbiomed.2018.09.008","volume":"133","author":"DA Stoyanovsky","year":"2019","unstructured":"Stoyanovsky DA, Tyurina YY, Shrivastava I, Bahar I, Tyurin VA, Protchenko O, Jadhav S, Bolevich SB, Kozlov AV, Vladimirov YA, Shvedova AA, Philpott CC, Bayir H, Kagan VE (2019) Iron catalysis of lipid peroxidation in ferroptosis: regulated enzymatic or random free radical reaction? Free Radic Biol Med 133:153\u2013161","journal-title":"Free Radic Biol Med"},{"issue":"10","key":"3963_CR55","doi-asserted-by":"publisher","first-page":"1690","DOI":"10.1038\/s41401-021-00700-w","volume":"42","author":"S Lu","year":"2021","unstructured":"Lu S, Wang XZ, He C, Wang L, Liang SP, Wang CC, Li C, Luo TF, Feng CS, Wang ZC, Chi GF, Ge PF (2021) ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and iron. Acta Pharmacol Sin 42(10):1690\u20131702","journal-title":"Acta Pharmacol Sin"},{"issue":"10","key":"3963_CR56","first-page":"3106","volume":"10","author":"W Lin","year":"2020","unstructured":"Lin W, Wang C, Liu G, Bi C, Wang X, Zhou Q, Jin H (2020) SLC7A11\/xCT in cancer: biological functions and therapeutic implications. Am J Cancer Res 10(10):3106\u20133126","journal-title":"Am J Cancer Res"},{"issue":"4","key":"3963_CR57","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1007\/s10637-021-01070-0","volume":"39","author":"MR Liu","year":"2021","unstructured":"Liu MR, Zhu WT, Pei DS (2021) System Xc(-): a key regulatory target of ferroptosis in cancer. Invest New Drugs 39(4):1123\u20131131","journal-title":"Invest New Drugs"},{"issue":"21","key":"3963_CR58","doi-asserted-by":"publisher","first-page":"R1292","DOI":"10.1016\/j.cub.2020.09.068","volume":"30","author":"D Tang","year":"2020","unstructured":"Tang D, Kroemer G (2020) Ferroptosis. Curr Biol 30(21):R1292\u2013R1297","journal-title":"Curr Biol"},{"key":"3963_CR59","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.freeradbiomed.2020.02.027","volume":"152","author":"F Ursini","year":"2020","unstructured":"Ursini F, Maiorino M (2020) Lipid peroxidation and ferroptosis: the role of GSH and GPx4. Free Radic Biol Med 152:175\u2013185","journal-title":"Free Radic Biol Med"},{"key":"3963_CR60","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.160839","volume":"862","author":"J Liu","year":"2022","unstructured":"Liu J, Yang G, Zhang H (2022) Glyphosate-triggered hepatocyte ferroptosis via suppressing Nrf2\/GSH\/GPX4 axis exacerbates hepatotoxicity. Sci Total Environ 862:160839","journal-title":"Sci Total Environ"},{"issue":"9","key":"3963_CR61","doi-asserted-by":"publisher","first-page":"1790","DOI":"10.1038\/s41418-022-00966-5","volume":"29","author":"CG Hsu","year":"2022","unstructured":"Hsu CG, Chavez CL, Zhang C, Sowden M, Yan C, Berk BC (2022) The lipid peroxidation product 4-hydroxynonenal inhibits NLRP3 inflammasome activation and macrophage pyroptosis. Cell Death Differ 29(9):1790\u20131803","journal-title":"Cell Death Differ"},{"issue":"8","key":"3963_CR62","doi-asserted-by":"publisher","first-page":"1582","DOI":"10.1038\/s41418-022-00947-8","volume":"29","author":"T Xu","year":"2022","unstructured":"Xu T, Yu W, Fang H, Wang Z, Chi Z, Guo X, Jiang D, Zhang K, Chen S, Li M, Guo Y, Zhang J, Yang D, Yu Q, Wang D, Zhang X (2022) Ubiquitination of NLRP3 by gp78\/Insig-1 restrains NLRP3 inflammasome activation. Cell Death Differ 29(8):1582\u20131595","journal-title":"Cell Death Differ"},{"key":"3963_CR63","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1146\/annurev-immunol-101220-030653","volume":"40","author":"C Ross","year":"2022","unstructured":"Ross C, Chan AH, von Pein JB, Maddugoda MP, Boucher D, Schroder K (2022) Inflammatory caspases: toward a unified model for caspase activation by inflammasomes. Annu Rev Immunol 40:249\u2013269","journal-title":"Annu Rev Immunol"},{"issue":"40","key":"3963_CR64","doi-asserted-by":"publisher","first-page":"eaau4643","DOI":"10.1126\/sciimmunol.aau4643","volume":"4","author":"S Lee","year":"2019","unstructured":"Lee S, Ishitsuka A, Noguchi M, Hirohama M, Fujiyasu Y, Petric PP, Schwemmle M, Staeheli P, Nagata K, Kawaguchi A (2019) Influenza restriction factor MxA functions as inflammasome sensor in the respiratory epithelium. Sci Immunol 4(40):eaau4643","journal-title":"Sci Immunol"},{"issue":"4","key":"3963_CR65","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1007\/s00401-018-01957-y","volume":"137","author":"IC Stancu","year":"2019","unstructured":"Stancu IC, Cremers N, Vanrusselt H, Couturier J, Vanoosthuyse A, Kessels S, Lodder C, Brone B, Huaux F, Octave JN, Terwel D, Dewachter I (2019) Aggregated Tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo. Acta Neuropathol 137(4):599\u2013617","journal-title":"Acta Neuropathol"},{"key":"3963_CR66","doi-asserted-by":"crossref","unstructured":"Zhang P, Liu Y, Hu L, Huang K, Hong M, Wang Y, Fan X, Ulevitch RJ, Han J (2021) NLRC4 inflammasome-dependent cell death occurs by a complementary series of three death pathways and determines lethality in mice. Sci Adv 7(43):eabi9471","DOI":"10.1126\/sciadv.abi9471"},{"issue":"20","key":"3963_CR67","doi-asserted-by":"publisher","DOI":"10.1172\/JCI136329","volume":"131","author":"J Wu","year":"2021","unstructured":"Wu J, Raman A, Coffey NJ, Sheng X, Wahba J, Seasock MJ, Ma Z, Beckerman P, Laczko D, Palmer MB, Kopp JB, Kuo JJ, Pullen SS, Boustany-Kari CM, Linkermann A, Susztak K (2021) The key role of NLRP3 and STING in APOL1-associated podocytopathy. J Clin Invest 131(20):e136329","journal-title":"J Clin Invest"},{"issue":"19","key":"3963_CR68","doi-asserted-by":"publisher","first-page":"8281","DOI":"10.1021\/acs.nanolett.1c02790","volume":"21","author":"B Ding","year":"2021","unstructured":"Ding B, Sheng J, Zheng P, Li C, Li D, Cheng Z, Ma P, Lin J (2021) Biodegradable upconversion nanoparticles induce pyroptosis for cancer immunotherapy. Nano Lett 21(19):8281\u20138289","journal-title":"Nano Lett"},{"issue":"9","key":"3963_CR69","doi-asserted-by":"publisher","first-page":"2651","DOI":"10.1038\/s41418-020-0536-x","volume":"27","author":"J Liu","year":"2020","unstructured":"Liu J, Du S, Kong Q, Zhang X, Jiang S, Cao X, Li Y, Li C, Chen H, Ding Z, Liu L (2020) HSPA12A attenuates lipopolysaccharide-induced liver injury through inhibiting caspase-11-mediated hepatocyte pyroptosis via PGC-1alpha-dependent acyloxyacyl hydrolase expression. Cell Death Differ 27(9):2651\u20132667","journal-title":"Cell Death Differ"},{"issue":"1","key":"3963_CR70","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1111\/imr.12534","volume":"277","author":"SM Man","year":"2017","unstructured":"Man SM, Karki R, Kanneganti TD (2017) Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases. Immunol Rev 277(1):61\u201375","journal-title":"Immunol Rev"},{"issue":"7661","key":"3963_CR71","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1038\/nature22393","volume":"547","author":"Y Wang","year":"2017","unstructured":"Wang Y, Gao W, Shi X, Ding J, Liu W, He H, Wang K, Shao F (2017) Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin. Nature 547(7661):99\u2013103","journal-title":"Nature"},{"issue":"46","key":"3963_CR72","doi-asserted-by":"publisher","first-page":"E10888","DOI":"10.1073\/pnas.1809548115","volume":"115","author":"J Sarhan","year":"2018","unstructured":"Sarhan J, Liu BC, Muendlein HI, Li P, Nilson R, Tang AY, Rongvaux A, Bunnell SC, Shao F, Green DR, Poltorak A (2018) Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection. Proc Natl Acad Sci USA 115(46):E10888\u2013E10897","journal-title":"Proc Natl Acad Sci USA"},{"issue":"10","key":"3963_CR73","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1038\/s41556-020-0575-z","volume":"22","author":"J Hou","year":"2020","unstructured":"Hou J, Zhao R, Xia W, Chang CW, You Y, Hsu JM, Nie L, Chen Y, Wang YC, Liu C, Wang WJ, Wu Y, Ke B, Hsu JL, Huang K, Ye Z, Yang Y, Xia X, Li Y, Li CW, Shao B, Tainer JA, Hung MC (2020) PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis. Nat Cell Biol 22(10):1264\u20131275","journal-title":"Nat Cell Biol"},{"issue":"11","key":"3963_CR74","doi-asserted-by":"publisher","first-page":"2924","DOI":"10.1016\/j.celrep.2018.02.067","volume":"22","author":"H Kambara","year":"2018","unstructured":"Kambara H, Liu F, Zhang X, Liu P, Bajrami B, Teng Y, Zhao L, Zhou S, Yu H, Zhou W, Silberstein LE, Cheng T, Han M, Xu Y, Luo HR (2018) Gasdermin D exerts anti-inflammatory effects by promoting neutrophil death. Cell Rep 22(11):2924\u20132936","journal-title":"Cell Rep"},{"issue":"6494","key":"3963_CR75","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaz7548","volume":"368","author":"Z Zhou","year":"2020","unstructured":"Zhou Z, He H, Wang K, Shi X, Wang Y, Su Y, Wang Y, Li D, Liu W, Zhang Y, Shen L, Han W, Shen L, Ding J, Shao F (2020) Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells. Science 368(6494):eaaz7548","journal-title":"Science"},{"issue":"2","key":"3963_CR76","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1007\/s12031-018-1155-6","volume":"66","author":"JR Wu","year":"2018","unstructured":"Wu JR, Tuo QZ, Lei P (2018) Ferroptosis, a recent defined form of critical cell death in neurological disorders. J Mol Neurosci 66(2):197\u2013206","journal-title":"J Mol Neurosci"},{"issue":"2","key":"3963_CR77","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1007\/s12011-012-9564-9","volume":"151","author":"LN An","year":"2013","unstructured":"An LN, Yue Y, Guo WZ, Miao YL, Mi WD, Zhang H, Lei ZL, Han SJ, Dong L (2013) Surgical trauma induces iron accumulation and oxidative stress in a rodent model of postoperative cognitive dysfunction. Biol Trace Elem Res 151(2):277\u2013283","journal-title":"Biol Trace Elem Res"},{"key":"3963_CR78","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1016\/j.neuropharm.2016.09.004","volume":"111","author":"K Pan","year":"2016","unstructured":"Pan K, Li X, Chen Y, Zhu D, Li Y, Tao G, Zuo Z (2016) Deferoxamine pre-treatment protects against postoperative cognitive dysfunction of aged rats by depressing microglial activation via ameliorating iron accumulation in hippocampus. Neuropharmacology 111:180\u2013194","journal-title":"Neuropharmacology"},{"key":"3963_CR79","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.bbi.2015.08.002","volume":"51","author":"LL Qiu","year":"2016","unstructured":"Qiu LL, Ji MH, Zhang H, Yang JJ, Sun XR, Tang H, Wang J, Liu WX, Yang JJ (2016) NADPH oxidase 2-derived reactive oxygen species in the hippocampus might contribute to microglial activation in postoperative cognitive dysfunction in aged mice. Brain Behav Immun 51:109\u2013118","journal-title":"Brain Behav Immun"},{"issue":"1","key":"3963_CR80","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.exger.2012.03.010","volume":"48","author":"F Rosenfeldt","year":"2013","unstructured":"Rosenfeldt F, Wilson M, Lee G, Kure C, Ou R, Braun L, de Haan J (2013) Oxidative stress in surgery in an ageing population: pathophysiology and therapy. Exp Gerontol 48(1):45\u201354","journal-title":"Exp Gerontol"},{"key":"3963_CR81","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.jconrel.2021.04.013","volume":"334","author":"J Yang","year":"2021","unstructured":"Yang J, Ma S, Xu R, Wei Y, Zhang J, Zuo T, Wang Z, Deng H, Yang N, Shen Q (2021) Smart biomimetic metal organic frameworks based on ROS-ferroptosis-glycolysis regulation for enhanced tumor chemo-immunotherapy. J Control Release 334:21\u201333","journal-title":"J Control Release"},{"issue":"3","key":"3963_CR82","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.tcb.2015.10.014","volume":"26","author":"WS Yang","year":"2016","unstructured":"Yang WS, Stockwell BR (2016) Ferroptosis: death by lipid peroxidation. Trends Cell Biol 26(3):165\u2013176","journal-title":"Trends Cell Biol"},{"issue":"18","key":"3963_CR83","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.21037\/atm-21-4249","volume":"9","author":"L Cheng","year":"2021","unstructured":"Cheng L, Zhu X, Liu Y, Zhu K, Lin K, Li F (2021) ACSL4 contributes to sevoflurane-induced ferroptotic neuronal death in SH-SY5Y cells via the 5\u2019 AMP-activated protein kinase\/mammalian target of rapamycin pathway. Ann Transl Med 9(18):1454","journal-title":"Ann Transl Med"},{"issue":"1","key":"3963_CR84","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1186\/s12974-020-01777-6","volume":"17","author":"J Wu","year":"2020","unstructured":"Wu J, Yang JJ, Cao Y, Li H, Zhao H, Yang S, Li K (2020) Iron overload contributes to general anaesthesia-induced neurotoxicity and cognitive deficits. J Neuroinflammation 17(1):110","journal-title":"J Neuroinflammation"},{"key":"3963_CR85","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2021.147328","volume":"1757","author":"M Wang","year":"2021","unstructured":"Wang M, Zuo Y, Li X, Li Y, Thirupathi A, Yu P, Gao G, Zhou C, Chang Y, Shi Z (2021) Effect of sevoflurane on iron homeostasis and toxicity in the brain of mice. Brain Res 1757:147328","journal-title":"Brain Res"},{"key":"3963_CR86","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2020.104693","volume":"135","author":"Y Zuo","year":"2020","unstructured":"Zuo Y, Li B, Xie J, Ma Z, Thirupathi A, Yu P, Gao G, Zhou J, Zhou C, Xu H, Chang Y, Shi Z (2020) Sevoflurane anesthesia during pregnancy in mice induces cognitive impairment in the offspring by causing iron deficiency and inhibiting myelinogenesis. Neurochem Int 135:104693","journal-title":"Neurochem Int"},{"key":"3963_CR87","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1016\/j.neuro.2016.04.015","volume":"60","author":"C Wang","year":"2017","unstructured":"Wang C, Liu F, Patterson TA, Paule MG, Slikker W Jr (2017) Relationship between ketamine-induced developmental neurotoxicity and NMDA receptor-mediated calcium influx in neural stem cell-derived neurons. Neurotoxicology 60:254\u2013259","journal-title":"Neurotoxicology"},{"key":"3963_CR88","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.ijdevneu.2016.01.008","volume":"54","author":"X Zhang","year":"2016","unstructured":"Zhang X, Shen F, Xu D, Zhao X (2016) A lasting effect of postnatal sevoflurane anesthesia on the composition of NMDA receptor subunits in rat prefrontal cortex. Int J Dev Neurosci 54:62\u201369","journal-title":"Int J Dev Neurosci"},{"issue":"8","key":"3963_CR89","doi-asserted-by":"publisher","first-page":"3582","DOI":"10.1523\/JNEUROSCI.1497-12.2013","volume":"33","author":"Y Chen","year":"2013","unstructured":"Chen Y, Khan RS, Cwanger A, Song Y, Steenstra C, Bang S, Cheah JH, Dunaief J, Shindler KS, Snyder SH, Kim SF (2013) Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity. J Neurosci 33(8):3582\u20133587","journal-title":"J Neurosci"},{"issue":"4","key":"3963_CR90","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1016\/j.neuron.2006.07.011","volume":"51","author":"JH Cheah","year":"2006","unstructured":"Cheah JH, Kim SF, Hester LD, Clancy KW, Patterson SE 3rd, Papadopoulos V, Snyder SH (2006) NMDA receptor-nitric oxide transmission mediates neuronal iron homeostasis via the GTPase Dexras1. Neuron 51(4):431\u2013440","journal-title":"Neuron"},{"key":"3963_CR91","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/s13041-016-0220-8","volume":"9","author":"RS White","year":"2016","unstructured":"White RS, Bhattacharya AK, Chen Y, Byrd M, McMullen MF, Siegel SJ, Carlson GC, Kim SF (2016) Lysosomal iron modulates NMDA receptor-mediated excitation via small GTPase, Dexras1. Mol Brain 9:38","journal-title":"Mol Brain"},{"key":"3963_CR92","doi-asserted-by":"publisher","first-page":"9800794","DOI":"10.1155\/2021\/9800794","volume":"2021","author":"H Zhang","year":"2021","unstructured":"Zhang H, Ostrowski R, Jiang D, Zhao Q, Liang Y, Che X, Zhao J, Xiang X, Qin W, He Z (2021) Hepcidin promoted ferroptosis through iron metabolism which is associated with DMT1 signaling activation in early brain injury following subarachnoid hemorrhage. Oxid Med Cell Longev 2021:9800794","journal-title":"Oxid Med Cell Longev"},{"issue":"9","key":"3963_CR93","doi-asserted-by":"publisher","first-page":"3727","DOI":"10.1182\/blood-2005-06-2259","volume":"107","author":"C Peyssonnaux","year":"2006","unstructured":"Peyssonnaux C, Zinkernagel AS, Datta V, Lauth X, Johnson RS, Nizet V (2006) TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens. Blood 107(9):3727\u20133732","journal-title":"Blood"},{"key":"3963_CR94","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2020.105239","volume":"163","author":"N Sumneang","year":"2021","unstructured":"Sumneang N, Apaijai N, Chattipakorn SC, Chattipakorn N (2021) Myeloid differentiation factor 2 in the heart: bench to bedside evidence for potential clinical benefits? Pharmacol Res 163:105239","journal-title":"Pharmacol Res"},{"issue":"11","key":"3963_CR95","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.23190","volume":"36","author":"H Shen","year":"2022","unstructured":"Shen H, Zhai L, Wang G (2022) Hepcidin regulates neuronal ferroptosis: a mechanism for postoperative cognitive dysfunction. J Biochem Mol Toxicol 36(11):e23190","journal-title":"J Biochem Mol Toxicol"},{"issue":"11","key":"3963_CR96","doi-asserted-by":"publisher","first-page":"1134","DOI":"10.1093\/abbs\/gmz104","volume":"51","author":"R Liu","year":"2019","unstructured":"Liu R, Li X, Zhao G (2019) Beclin1-mediated ferroptosis activation is associated with isoflurane-induced toxicity in SH-SY5Y neuroblastoma cells. Acta Biochim Biophys Sin (Shanghai) 51(11):1134\u20131141","journal-title":"Acta Biochim Biophys Sin (Shanghai)"},{"issue":"1\u20132","key":"3963_CR97","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/j.cell.2013.12.010","volume":"156","author":"WS Yang","year":"2014","unstructured":"Yang WS, SriRamaratnam R, Welsch ME, Shimada K, Skouta R, Viswanathan VS, Cheah JH, Clemons PA, Shamji AF, Clish CB, Brown LM, Girotti AW, Cornish VW, Schreiber SL, Stockwell BR (2014) Regulation of ferroptotic cancer cell death by GPX4. Cell 156(1\u20132):317\u2013331","journal-title":"Cell"},{"issue":"11\u201312","key":"3963_CR98","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1080\/10715762.2019.1666983","volume":"54","author":"J Fujii","year":"2020","unstructured":"Fujii J, Homma T, Kobayashi S (2020) Ferroptosis caused by cysteine insufficiency and oxidative insult. Free Radic Res 54(11\u201312):969\u2013980","journal-title":"Free Radic Res"},{"key":"3963_CR99","doi-asserted-by":"publisher","first-page":"486","DOI":"10.3389\/fnmol.2018.00486","volume":"11","author":"Y Xia","year":"2018","unstructured":"Xia Y, Sun X, Luo Y, Stary CM (2018) Ferroptosis contributes to isoflurane neurotoxicity. Front Mol Neurosci 11:486","journal-title":"Front Mol Neurosci"},{"issue":"13","key":"3963_CR100","doi-asserted-by":"publisher","first-page":"2399","DOI":"10.1021\/acschemneuro.1c00131","volume":"12","author":"L Zhao","year":"2021","unstructured":"Zhao L, Gong H, Huang H, Tuerhong G, Xia H (2021) Participation of mind bomb-2 in sevoflurane anesthesia induces cognitive impairment in aged mice via modulating ferroptosis. ACS Chem Neurosci 12(13):2399\u20132408","journal-title":"ACS Chem Neurosci"},{"key":"3963_CR101","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.pneurobio.2013.10.003","volume":"112","author":"MV Caldeira","year":"2014","unstructured":"Caldeira MV, Salazar IL, Curcio M, Canzoniero LM, Duarte CB (2014) Role of the ubiquitin-proteasome system in brain ischemia: friend or foe? Prog Neurobiol 112:50\u201369","journal-title":"Prog Neurobiol"},{"key":"3963_CR102","doi-asserted-by":"crossref","unstructured":"An Z, Chiang WC, Fernandez AF, Franco LH, He C, Huang SY, Lee E, Liu Y, Sebti S, Shoji-Kawata S, Sirasanagandla S, Wang RC, Wei Y, Zhao Y, Vega-Rubin-de-Celis S (2022) Beth Levine's legacy: from the discovery of BECN1 to therapies. A Mentees' perspective. Front Cell Dev Biol 10:891332","DOI":"10.3389\/fcell.2022.891332"},{"key":"3963_CR103","doi-asserted-by":"crossref","unstructured":"Song X, Zhu S, Chen P, Hou W, Wen Q, Liu J, Xie Y, Liu J, Klionsky DJ, Kroemer G, Lotze MT, Zeh HJ, Kang R, Tang D (2018) AMPK-mediated BECN1 phosphorylation promotes ferroptosis by directly blocking system X(c)(-) activity. Curr Biol 28(15):2388\u20132399 e2385","DOI":"10.1016\/j.cub.2018.05.094"},{"issue":"18","key":"3963_CR104","doi-asserted-by":"publisher","first-page":"22375","DOI":"10.18632\/aging.203544","volume":"13","author":"X Ge","year":"2021","unstructured":"Ge X, Zuo Y, Xie J, Li X, Li Y, Thirupathi A, Yu P, Gao G, Zhou C, Chang Y, Shi Z (2021) A new mechanism of POCD caused by sevoflurane in mice: cognitive impairment induced by cross-dysfunction of iron and glucose metabolism. Aging (Albany NY) 13(18):22375\u201322389","journal-title":"Aging (Albany NY)"},{"issue":"2","key":"3963_CR105","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/s41556-020-0461-8","volume":"22","author":"H Lee","year":"2020","unstructured":"Lee H, Zandkarimi F, Zhang Y, Meena JK, Kim J, Zhuang L, Tyagi S, Ma L, Westbrook TF, Steinberg GR, Nakada D, Stockwell BR, Gan B (2020) Energy-stress-mediated AMPK activation inhibits ferroptosis. Nat Cell Biol 22(2):225\u2013234","journal-title":"Nat Cell Biol"},{"issue":"11","key":"3963_CR106","doi-asserted-by":"publisher","first-page":"7781","DOI":"10.1021\/acs.nanolett.9b02795","volume":"19","author":"L Li","year":"2019","unstructured":"Li L, Sun S, Tan L, Wang Y, Wang L, Zhang Z, Zhang L (2019) Polystyrene nanoparticles reduced ROS and inhibited ferroptosis by triggering lysosome stress and TFEB nucleus translocation in a size-dependent manner. Nano Lett 19(11):7781\u20137792","journal-title":"Nano Lett"},{"issue":"3","key":"3963_CR107","doi-asserted-by":"publisher","first-page":"245","DOI":"10.2174\/1567202619666220802104426","volume":"19","author":"C Chen","year":"2022","unstructured":"Chen C, Zuo J, Zhang H (2022) Sevoflurane post-treatment mitigates oxygen-glucose deprivation-induced pyroptosis of hippocampal neurons by regulating the Mafb\/DUSP14 axis. Curr Neurovasc Res 19(3):245\u2013254","journal-title":"Curr Neurovasc Res"},{"issue":"1","key":"3963_CR108","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1186\/s12974-018-1137-1","volume":"15","author":"Z Wang","year":"2018","unstructured":"Wang Z, Meng S, Cao L, Chen Y, Zuo Z, Peng S (2018) Critical role of NLRP3-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment. J Neuroinflammation 15(1):109","journal-title":"J Neuroinflammation"},{"issue":"1","key":"3963_CR109","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1186\/s12974-018-1299-x","volume":"15","author":"L Yin","year":"2018","unstructured":"Yin L, Bao F, Wu J, Li K (2018) NLRP3 inflammasome-dependent pyroptosis is proposed to be involved in the mechanism of age-dependent isoflurane-induced cognitive impairment. J Neuroinflammation 15(1):266","journal-title":"J Neuroinflammation"},{"key":"3963_CR110","doi-asserted-by":"publisher","first-page":"426","DOI":"10.3389\/fncel.2018.00426","volume":"12","author":"Y Fan","year":"2018","unstructured":"Fan Y, Du L, Fu Q, Zhou Z, Zhang J, Li G, Wu J (2018) Inhibiting the NLRP3 inflammasome with MCC950 ameliorates isoflurane-induced pyroptosis and cognitive impairment in aged mice. Front Cell Neurosci 12:426","journal-title":"Front Cell Neurosci"},{"issue":"1","key":"3963_CR111","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.devcel.2016.03.002","volume":"37","author":"MJ Oudhoff","year":"2016","unstructured":"Oudhoff MJ, Braam MJS, Freeman SA, Wong D, Rattray DG, Wang J, Antignano F, Snyder K, Refaeli I, Hughes MR, McNagny KM, Gold MR, Arrowsmith CH, Sato T, Rossi FMV, Tatlock JH, Owen DR, Brown PJ, Zaph C (2016) SETD7 controls intestinal regeneration and tumorigenesis by regulating Wnt\/beta-catenin and Hippo\/YAP signaling. Dev Cell 37(1):47\u201357","journal-title":"Dev Cell"},{"issue":"11","key":"3963_CR112","doi-asserted-by":"publisher","first-page":"541","DOI":"10.5483\/BMBRep.2022.55.11.080","volume":"55","author":"SH Kim","year":"2022","unstructured":"Kim SH, Park J, Park JW, Hahm JY, Yoon S, Hwang IJ, Kim KP, Seo SB (2022) SET7-mediated TIP60 methylation is essential for DNA double-strand break repair. BMB Rep 55(11):541\u2013546","journal-title":"BMB Rep"},{"key":"3963_CR113","doi-asserted-by":"publisher","first-page":"960327121106149","DOI":"10.1177\/09603271211061497","volume":"41","author":"C Ma","year":"2022","unstructured":"Ma C, Yu X, Li D, Fan Y, Tang Y, Tao Q, Zheng L (2022) Inhibition of SET domain-containing (lysine methyltransferase) 7 alleviates cognitive impairment through suppressing the activation of NOD-like receptor protein 3 inflammasome in isoflurane-induced aged mice. Hum Exp Toxicol 41:9603271211061496","journal-title":"Hum Exp Toxicol"},{"issue":"1","key":"3963_CR114","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1186\/s12974-021-02233-9","volume":"18","author":"J Dai","year":"2021","unstructured":"Dai J, Li X, Wang C, Gu S, Dai L, Zhang J, Fan Y, Wu J (2021) Repeated neonatal sevoflurane induced neurocognitive impairment through NF-kappaB-mediated pyroptosis. J Neuroinflammation 18(1):180","journal-title":"J Neuroinflammation"},{"issue":"8","key":"3963_CR115","doi-asserted-by":"publisher","first-page":"2012","DOI":"10.1038\/jid.2015.119","volume":"135","author":"DJ Lee","year":"2015","unstructured":"Lee DJ, Du F, Chen SW, Nakasaki M, Rana I, Shih VFS, Hoffmann A, Jamora C (2015) Regulation and function of the caspase-1 in an inflammatory microenvironment. J Invest Dermatol 135(8):2012\u20132020","journal-title":"J Invest Dermatol"},{"issue":"12","key":"3963_CR116","doi-asserted-by":"publisher","first-page":"1012","DOI":"10.1016\/j.tibs.2016.09.002","volume":"41","author":"Y He","year":"2016","unstructured":"He Y, Hara H, Nunez G (2016) Mechanism and REGULATION of NLRP3 inflammasome activation. Trends Biochem Sci 41(12):1012\u20131021","journal-title":"Trends Biochem Sci"},{"issue":"7","key":"3963_CR117","doi-asserted-by":"publisher","first-page":"3621","DOI":"10.1172\/JCI130176","volume":"130","author":"L Ye","year":"2020","unstructured":"Ye L, Li G, Goebel A, Raju AV, Kong F, Lv Y, Li K, Zhu Y, Raja S, He P, Li F, Mwangi SM, Hu W, Srinivasan S (2020) Caspase-11-mediated enteric neuronal pyroptosis underlies Western diet-induced colonic dysmotility. J Clin Invest 130(7):3621\u20133636","journal-title":"J Clin Invest"},{"issue":"1","key":"3963_CR118","doi-asserted-by":"publisher","first-page":"197","DOI":"10.4049\/jimmunol.166.1.197","volume":"166","author":"F Marti","year":"2001","unstructured":"Marti F, Krause A, Post NH, Lyddane C, Dupont B, Sadelain M, King PD (2001) Negative-feedback regulation of CD28 costimulation by a novel mitogen-activated protein kinase phosphatase, MKP6. J Immunol 166(1):197\u2013206","journal-title":"J Immunol"},{"issue":"4","key":"3963_CR119","doi-asserted-by":"publisher","first-page":"1320","DOI":"10.1002\/hep.29616","volume":"67","author":"S Wang","year":"2018","unstructured":"Wang S, Yan ZZ, Yang X, An S, Zhang K, Qi Y, Zheng J, Ji YX, Wang PX, Fang C, Zhu XY, Shen LJ, Yan FJ, Bao R, Tian S, She ZG, Tang YD (2018) Hepatocyte DUSP14 maintains metabolic homeostasis and suppresses inflammation in the liver. Hepatology 67(4):1320\u20131338","journal-title":"Hepatology"},{"issue":"3","key":"3963_CR120","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/j.bbrc.2018.12.170","volume":"509","author":"S Jianrong","year":"2019","unstructured":"Jianrong S, Yanjun Z, Chen Y, Jianwen X (2019) DUSP14 rescues cerebral ischemia\/reperfusion (IR) injury by reducing inflammation and apoptosis via the activation of Nrf-2. Biochem Biophys Res Commun 509(3):713\u2013721","journal-title":"Biochem Biophys Res Commun"},{"issue":"12","key":"3963_CR121","first-page":"7101","volume":"24","author":"YY Que","year":"2020","unstructured":"Que YY, Zhu T, Zhang FX, Peng J (2020) Neuroprotective effect of DUSP14 overexpression against isoflurane-induced inflammatory response, pyroptosis and cognitive impairment in aged rats through inhibiting the NLRP3 inflammasome. Eur Rev Med Pharmacol Sci 24(12):7101\u20137113","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"3963_CR122","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2022.840143","volume":"16","author":"G Wei","year":"2022","unstructured":"Wei G, Zhang X, Cai C, Sheng J, Xu M, Wang C, Gu Q, Guo C, Chen F, Liu D, Qian F (2022) Dual-specificity phosphatase 14 regulates zebrafish hair cell formation through activation of p38 signaling pathway. Front Cell Neurosci 16:840143","journal-title":"Front Cell Neurosci"},{"issue":"2","key":"3963_CR123","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1007\/s00395-016-0536-7","volume":"111","author":"CY Li","year":"2016","unstructured":"Li CY, Zhou Q, Yang LC, Chen YH, Hou JW, Guo K, Wang YP, Li YG (2016) Dual-specificity phosphatase 14 protects the heart from aortic banding-induced cardiac hypertrophy and dysfunction through inactivation of TAK1-P38MAPK\/-JNK1\/2 signaling pathway. Basic Res Cardiol 111(2):19","journal-title":"Basic Res Cardiol"},{"issue":"5","key":"3963_CR124","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1080\/02713683.2020.1826976","volume":"46","author":"V Kumar","year":"2021","unstructured":"Kumar V, Ali Shariati M, Mesentier-Louro L, Jinsook OhA, Russano K, Goldberg JL, Liao YJ (2021) Dual specific phosphatase 14 deletion rescues retinal ganglion cells and optic nerve axons after experimental anterior ischemic optic neuropathy. Curr Eye Res 46(5):710\u2013718","journal-title":"Curr Eye Res"},{"issue":"21","key":"3963_CR125","doi-asserted-by":"publisher","first-page":"3508","DOI":"10.1016\/j.febslet.2009.10.010","volume":"583","author":"D Goven","year":"2009","unstructured":"Goven D, Boutten A, Lecon-Malas V, Boczkowski J, Bonay M (2009) Prolonged cigarette smoke exposure decreases heme oxygenase-1 and alters Nrf2 and Bach1 expression in human macrophages: roles of the MAP kinases ERK(1\/2) and JNK. FEBS Lett 583(21):3508\u20133518","journal-title":"FEBS Lett"},{"issue":"8\u20139","key":"3963_CR126","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1080\/15216540701225941","volume":"59","author":"S Hira","year":"2007","unstructured":"Hira S, Tomita T, Matsui T, Igarashi K, Ikeda-Saito M (2007) Bach1, a heme-dependent transcription factor, reveals presence of multiple heme binding sites with distinct coordination structure. IUBMB Life 59(8\u20139):542\u2013551","journal-title":"IUBMB Life"},{"key":"3963_CR127","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1016\/j.brainresbull.2017.01.016","volume":"130","author":"R Li","year":"2017","unstructured":"Li R, Zhang LM, Sun WB (2017) Erythropoietin rescues primary rat cortical neurons from pyroptosis and apoptosis via Erk1\/2-Nrf2\/Bach1 signal pathway. Brain Res Bull 130:236\u2013244","journal-title":"Brain Res Bull"},{"issue":"12","key":"3963_CR128","doi-asserted-by":"publisher","first-page":"2065","DOI":"10.1002\/jcb.24883","volume":"115","author":"AG Paquette","year":"2014","unstructured":"Paquette AG, Marsit CJ (2014) The developmental basis of epigenetic regulation of HTR2A and psychiatric outcomes. J Cell Biochem 115(12):2065\u20132072","journal-title":"J Cell Biochem"},{"issue":"3","key":"3963_CR129","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1002\/jnr.20732","volume":"83","author":"OO Polesskaya","year":"2006","unstructured":"Polesskaya OO, Aston C, Sokolov BP (2006) Allele C-specific methylation of the 5-HT2A receptor gene: evidence for correlation with its expression and expression of DNA methylase DNMT1. J Neurosci Res 83(3):362\u2013373","journal-title":"J Neurosci Res"},{"key":"3963_CR130","doi-asserted-by":"crossref","unstructured":"Marinova Z, Walitza S, Grunblatt E (2013) 5-HT2A serotonin receptor agonist DOI alleviates cytotoxicity in neuroblastoma cells: role of the ERK pathway. Prog Neuropsychopharmacol Biol Psychiatry 44:64\u201372","DOI":"10.1016\/j.pnpbp.2013.01.017"},{"issue":"4","key":"3963_CR131","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2021.167379","volume":"434","author":"Y Hu","year":"2022","unstructured":"Hu Y, Wang B, Li S, Yang S (2022) Pyroptosis, and its role in central nervous system disease. J Mol Biol 434(4):167379","journal-title":"J Mol Biol"},{"issue":"1","key":"3963_CR132","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1007\/s12035-022-03070-4","volume":"60","author":"W Wen-Yuan","year":"2022","unstructured":"Wen-Yuan W, Wan-Qing Y, Qi-Yun H, Yu-Si L, Shao-Jie Q, Jin-Tao L, Hui M, Fang C, Hui-Ling Y (2022) mTORC1-dependent and GSDMD-mediated pyroptosis in developmental sevoflurane neurotoxicity. Mol Neurobiol 60(1):116\u2013132","journal-title":"Mol Neurobiol"},{"issue":"5","key":"3963_CR133","doi-asserted-by":"publisher","first-page":"1413","DOI":"10.1080\/13813455.2020.1773860","volume":"128","author":"H Chen","year":"2022","unstructured":"Chen H, Peng Y, Wang L, Wang X (2022) Sevoflurane attenuates cognitive dysfunction and NLRP3-dependent caspase-1\/11-GSDMD pathway-mediated pyroptosis in the hippocampus via upregulation of SIRT1 in a sepsis model. Arch Physiol Biochem 128(5):1413\u20131420","journal-title":"Arch Physiol Biochem"},{"key":"3963_CR134","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2021.658860","volume":"13","author":"JH Kim","year":"2021","unstructured":"Kim JH, Jung H, Lee Y, Sohn JH (2021) Surgery performed under propofol anesthesia induces cognitive impairment and amyloid pathology in ApoE4 knock-in mouse model. Front Aging Neurosci 13:658860","journal-title":"Front Aging Neurosci"},{"issue":"2","key":"3963_CR135","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1007\/s11064-022-03754-2","volume":"48","author":"Z Ma","year":"2022","unstructured":"Ma Z, Ma Y, Cao X, Zhang Y, Song T (2022) Avenanthramide-C activates Nrf2\/ARE pathway and inhibiting ferroptosis pathway to improve cognitive dysfunction in aging rats. Neurochem Res 48(2):393\u2013403","journal-title":"Neurochem Res"},{"issue":"5","key":"3963_CR136","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1007\/s11064-021-03249-6","volume":"46","author":"H Gong","year":"2021","unstructured":"Gong H, Wan X, Zhang Y, Liang S (2021) Downregulation of HOTAIR reduces neuronal pyroptosis by targeting miR-455-3p\/NLRP1 axis in propofol-treated neurons in vitro. Neurochem Res 46(5):1141\u20131150","journal-title":"Neurochem Res"},{"key":"3963_CR137","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s12974-015-0238-3","volume":"12","author":"XY Zhang","year":"2015","unstructured":"Zhang XY, Cao JB, Zhang LM, Li YF, Mi WD (2015) Deferoxamine attenuates lipopolysaccharide-induced neuroinflammation and memory impairment in mice. J Neuroinflammation 12:20","journal-title":"J Neuroinflammation"},{"issue":"1","key":"3963_CR138","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1186\/s12974-016-0740-2","volume":"13","author":"Y Li","year":"2016","unstructured":"Li Y, Pan K, Chen L, Ning JL, Li X, Yang T, Terrando N, Gu J, Tao G (2016) Deferoxamine regulates neuroinflammation and iron homeostasis in a mouse model of postoperative cognitive dysfunction. J Neuroinflammation 13(1):268","journal-title":"J Neuroinflammation"},{"issue":"3","key":"3963_CR139","doi-asserted-by":"publisher","first-page":"1690","DOI":"10.1182\/blood-2007-07-102335","volume":"111","author":"YS Sohn","year":"2008","unstructured":"Sohn YS, Breuer W, Munnich A, Cabantchik ZI (2008) Redistribution of accumulated cell iron: a modality of chelation with therapeutic implications. Blood 111(3):1690\u20131699","journal-title":"Blood"},{"issue":"1","key":"3963_CR140","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1038\/s41420-021-00454-8","volume":"7","author":"P Liu","year":"2021","unstructured":"Liu P, Yuan J, Feng Y, Chen X, Wang G, Zhao L (2021) Ferroptosis contributes to isoflurane-induced neurotoxicity and learning and memory impairment. Cell Death Discov 7(1):72","journal-title":"Cell Death Discov"},{"key":"3963_CR141","doi-asserted-by":"publisher","first-page":"9268083","DOI":"10.1155\/2020\/9268083","volume":"2020","author":"D Liao","year":"2020","unstructured":"Liao D, Lv C, Cao L, Yao D, Wu Y, Long M, Liu N, Jiang P (2020) Curcumin attenuates chronic unpredictable mild stress-induced depressive-like behaviors via restoring changes in oxidative stress and the activation of Nrf2 signaling pathway in rats. Oxid Med Cell Longev 2020:9268083","journal-title":"Oxid Med Cell Longev"},{"issue":"13","key":"3963_CR142","doi-asserted-by":"publisher","first-page":"12943","DOI":"10.18632\/aging.103378","volume":"12","author":"H Dong","year":"2020","unstructured":"Dong H, Qiang Z, Chai D, Peng J, Xia Y, Hu R, Jiang H (2020) Nrf2 inhibits ferroptosis and protects against acute lung injury due to intestinal ischemia reperfusion via regulating SLC7A11 and HO-1. Aging (Albany NY) 12(13):12943\u201312959","journal-title":"Aging (Albany NY)"},{"key":"3963_CR143","doi-asserted-by":"publisher","first-page":"7272456","DOI":"10.1155\/2023\/7272456","volume":"2023","author":"L Li","year":"2023","unstructured":"Li L, Meng F, Li D (2023) Downregulation of Nrf2 in the hippocampus contributes to postoperative cognitive dysfunction in aged rats by sensitizing oxidative stress and neuroinflammation. Oxid Med Cell Longev 2023:7272456","journal-title":"Oxid Med Cell Longev"},{"key":"3963_CR144","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.brainresbull.2022.01.005","volume":"181","author":"D Hua","year":"2022","unstructured":"Hua D, Luo A, Wu Z, Huang C, Li S, Xu X, Xu J, Yang C, Wang D, Liu C (2022) Sulforaphane improves cognitive dysfunction after surgery and anesthesia in mice: the role of Keap1-Nrf2 signaling. Brain Res Bull 181:1\u201311","journal-title":"Brain Res Bull"},{"key":"3963_CR145","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.2147\/NDT.S364250","volume":"18","author":"Q Tang","year":"2022","unstructured":"Tang Q, Guo Q, Li K, Fei F (2022) VRT-043198 ameliorates surgery-induced neurocognitive disorders by restoring the NGF and BNDF expression in aged mice. Neuropsychiatr Dis Treat 18:1027\u20131037","journal-title":"Neuropsychiatr Dis Treat"},{"issue":"7717","key":"3963_CR146","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1038\/s41586-018-0372-z","volume":"560","author":"Z Zhong","year":"2018","unstructured":"Zhong Z, Liang S, Sanchez-Lopez E, He F, Shalapour S, Lin XJ, Wong J, Ding S, Seki E, Schnabl B, Hevener AL, Greenberg HB, Kisseleva T, Karin M (2018) New mitochondrial DNA synthesis enables NLRP3 inflammasome activation. Nature 560(7717):198\u2013203","journal-title":"Nature"},{"issue":"10","key":"3963_CR147","doi-asserted-by":"publisher","first-page":"5230","DOI":"10.4049\/jimmunol.1301490","volume":"191","author":"ME Heid","year":"2013","unstructured":"Heid ME, Keyel PA, Kamga C, Shiva S, Watkins SC, Salter RD (2013) Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation. J Immunol 191(10):5230\u20135238","journal-title":"J Immunol"},{"issue":"2","key":"3963_CR148","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/j.immuni.2013.08.001","volume":"39","author":"SS Iyer","year":"2013","unstructured":"Iyer SS, He Q, Janczy JR, Elliott EI, Zhong Z, Olivier AK, Sadler JJ, Knepper-Adrian V, Han R, Qiao L, Eisenbarth SC, Nauseef WM, Cassel SL, Sutterwala FS (2013) Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation. Immunity 39(2):311\u2013323","journal-title":"Immunity"},{"key":"3963_CR149","doi-asserted-by":"publisher","first-page":"251","DOI":"10.3389\/fncel.2020.00251","volume":"14","author":"Y Zuo","year":"2020","unstructured":"Zuo Y, Yin L, Cheng X, Li J, Wu H, Liu X, Gu E, Wu J (2020) Elamipretide attenuates pyroptosis and perioperative neurocognitive disorders in aged mice. Front Cell Neurosci 14:251","journal-title":"Front Cell Neurosci"},{"key":"3963_CR150","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.neuro.2022.09.007","volume":"93","author":"L Shu","year":"2022","unstructured":"Shu L, Du C (2022) PHLDA1 promotes sevoflurane-induced pyroptosis of neuronal cells in developing rats through TRAF6-mediated activation of Rac1. Neurotoxicology 93:140\u2013151","journal-title":"Neurotoxicology"},{"key":"3963_CR151","doi-asserted-by":"publisher","DOI":"10.1177\/10738584221100183","author":"S David","year":"2022","unstructured":"David S, Ryan F, Jhelum P, Kroner A (2022) Ferroptosis in neurological disease. Neuroscientist. https:\/\/doi.org\/10.1177\/10738584221100183","journal-title":"Neuroscientist"}],"container-title":["Neurochemical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11064-023-03963-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11064-023-03963-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11064-023-03963-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T10:15:35Z","timestamp":1693476935000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11064-023-03963-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,8]]},"references-count":151,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["3963"],"URL":"https:\/\/doi.org\/10.1007\/s11064-023-03963-3","relation":{},"ISSN":["0364-3190","1573-6903"],"issn-type":[{"value":"0364-3190","type":"print"},{"value":"1573-6903","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,8]]},"assertion":[{"value":"22 March 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 May 2023","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 June 2023","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 June 2023","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that there is no conflict of interest regarding the publication of this paper.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}